Dérivés du Benzimidazole et de l’Imidazole
Le benzimidazole est un composé constitué d’un noyau benzénique fusionné à un noyau imidazole, une structure à cinq membres contenant deux atomes d’azote. Les dérivés du benzimidazole, comme l’albendazole, sont connus pour leur activité antiparasitaire et antifongique, utilisés dans le traitement des infections parasitaires et de certaines maladies parasitaires chez les animaux et les humains. L’imidazole, quant à lui, est une structure à cinq membres avec deux atomes d’azote, présente dans divers composés biologiquement actifs. Les dérivés de l’imidazole, comme le métronidazole, possèdent des propriétés antimicrobiennes et antiparasitaires. Ces composés sont également utilisés dans l’industrie pharmaceutique pour le traitement des infections bactériennes, des maladies parasitaires et de certaines infections fongiques, ainsi qu’en chimie organique comme catalyseurs.
Chez CymitQuimica, nous proposons des benzimidazoles et des imidazoles de haute pureté pour la recherche en chimie médicinale, pharmacologie et biotechnologie.
10345 produits trouvés pour "Dérivés du Benzimidazole et de l’Imidazole"
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Trimebutine EP Impurity E-Nitroso
Produit contrôléFormule :C21H26N2O6Couleur et forme :NeatMasse moléculaire :402.4412-(Chloromethyl)-3,5-dimethylpyridine Hydrochloride
CAS :Produit contrôlé<p>Applications Intermediate in the preparation of Omeprazole metabolites<br></p>Formule :C8H10ClN·ClHCouleur et forme :NeatMasse moléculaire :192.096-Ethyl-5-fluoropyrimidin-4(3H)-one
CAS :Produit contrôlé<p>Applications A pyrimidine derivative used in the preparation of bio-active compounds such as broad-spectrum triazole antifungal agents.<br>References Butters, M. et al.: Org. Proc. Res. Dev., 5, 28 (2001); Tong, L. et al.: Zhong. Yao., 8, 280 (2010);<br></p>Formule :C6H7FN2OCouleur et forme :NeatMasse moléculaire :142.13Secnidazole Formate
Produit contrôléFormule :C8H11N3O4Couleur et forme :NeatMasse moléculaire :213.19(3S)-1-[2-(3-Ethenyl-4-hydroxyphenyl)ethyl]-α,α-diphenyl-3-pyrrolidineacetamide
CAS :Produit contrôléFormule :C28H30N2O2Couleur et forme :NeatMasse moléculaire :426.552,2'-Ethylenedianiline
CAS :Produit contrôlé<p>Applications 2,2'-Ethylenedianiline is used as a reagent to synthesize Oxcarbazepine (O869250), a broad-specturm, second-generation anticonvulsant drug that is used to treat partial and complex partial seizures in children and adults. 2,2'-Ethylenedianiline is also used as a reagent to prepare a series of triterpines (e.g. Lupeol [L474850]), compounds that have chemopreventative activity.<br>References Asmaa, M., et al.: Pac. J. Cancer Prevent., 15, 475 (2014); Kalis, M. & Huff, N.: Clin. Ther., 23, 680 (2001); Malke, S., et al.: Pharm. Sci., 69, 211 (2007); Schmidt, D. & Elger, C.: Epil. Beh., 5, 627 (2004)<br></p>Formule :C14H16N2Couleur et forme :NeatMasse moléculaire :212.29Voriconazole-d3 N-Oxide (~90%)
CAS :Produit contrôléFormule :C16D3H11F3N5O2Degré de pureté :~90%Couleur et forme :NeatMasse moléculaire :368.332-(2-Butyl)-4-{4-[4-(4-methyloxy-phenyl)-piperazin-1-yl]-phenyl}-2,4-dihydro-[1,2,4]-triazol-3-one
CAS :Produit contrôlé<p>Impurity Itraconazole EP Impurity A<br>Applications 2-(2-Butyl)-4-{4-[4-(4-methyloxy-phenyl)-piperazin-1-yl]-phenyl}-2,4-dihydro-[1,2,4]-triazol-3-one (Itraconazole EP Impurity A) is an intermediate of Itraconazole.<br></p>Formule :C23H29N5O2Couleur et forme :BeigeMasse moléculaire :407.51PD 224378
CAS :Produit contrôlé<p>Stability Very Hygroscopic<br>Applications PD 224378 is a lactose conjugate degradation product of pregabalin (P704800), a GABA analogue used as an anticonvulsant.<br>References Lovdahl, M.J., et al.: J. Pharma. Biomed. Anal., 28, 917 (2002);<br></p>Formule :C20H35NO11Couleur et forme :NeatMasse moléculaire :465.49Benzofuran-6-carboxylic Acid
CAS :Produit contrôlé<p>Applications Benzofuran-6-carboxylic Acid is a reagent in the development of potent LFA-1/ICAM antagonist SAR 118 as an opthalmic solution for treating dry eyes. Preparation of piperidinylpyrimidine derivatives as inhibitors of HIV-1 LTR activation.<br>References Zhong, M., et al.: ACS Med. Chem., 3, 203 (2012); Fujiwara, N., et al.: Bioorg. Med. Chem., 16, 9804 (2008)<br></p>Formule :C9H6O3Couleur et forme :NeatMasse moléculaire :162.14N-Nitroso Aryl Lurasidone
CAS :Produit contrôléFormule :C11H12N4OSCouleur et forme :NeatMasse moléculaire :248.312-(Ethylthio)ethanol
CAS :Produit contrôlé<p>Applications 2-(Ethylthio)ethanol is used to prepare aryldihydropyrimidinones as inhibitors of fatty acid transporter FATP4.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Blackburn, C., et al.: Bioorg. Med. Chem. Lett., 16, 3504 (2006)<br></p>Formule :C4H10OSCouleur et forme :NeatMasse moléculaire :106.19N-trifluoroacetyl Varenicline
CAS :Produit contrôlé<p>Applications 7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine is used to prepare varenicline, which is a smoking cessation. It is a Varenicline protected impurity.<br>References Coe, J., et al.: J. Med. Chem., 48, 3474 (2005) ;<br></p>Formule :C15H12F3N3OCouleur et forme :NeatMasse moléculaire :307.2705Oxybutynin-d10 Hydrochloride
CAS :Produit contrôlé<p>Applications Oxybutynin-d10 Hydrochloride is a labeled analogue of Oxybutynin Chloride (O868525), an inhibitor of proliferation and supresses gene expression in bladder smooth muscle cells.<br>References Park, J.M., et al.: J. Urol., 162, 1110 (1999); Watson, M., et al.: Brit. J. Pharmacol., 127, 590 (1999)<br></p>Formule :C22H22D10ClNO3Couleur et forme :NeatMasse moléculaire :404.014,4'-(1-Methylene) bis-Benzonitrile
CAS :Produit contrôlé<p>Applications 4,4'-(1-METHYLENE) BIS-BENZONITRILE (cas# 10466-37-2) is a useful research chemical.<br></p>Formule :C15H10N2Couleur et forme :White To Off-WhiteMasse moléculaire :218.252,4-Dicyano-3-(2-methylpropyl)-pentanediamide (Mixture of Diastereomers)
CAS :Produit contrôlé<p>Stability Hygrscopic<br>Applications 2,4-Dicyano-3-(2-methylpropyl)-pentanediamide is an impurity of Pregabalin (P704800), a GABA (A602920) analogue used as an anticonvulsant.<br>References Hoekstra, M.S., et al.: Org. Proc. Rec. Deve., 1, 26 (1997); Lowry, O., et al.: J. Biol. Chem., 193, 265 (1951); Gerlach, M., et al.: Brain Res., 741, 142 (1996); Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Formule :C11H16N4O2Couleur et forme :NeatMasse moléculaire :236.272-Chlorobenzotrichloride
CAS :Produit contrôlé<p>Applications 2-Chlorobenzotrichloride is a chlorinated toluene with mutagenicity.<br>References Mineki, S. et al.: Mat. technol., 23, 413 (2005); Matsushita, H. et al.: Indust. Health., 17, 199 (1979);<br></p>Formule :C7H4Cl4Couleur et forme :NeatMasse moléculaire :229.9210-Chloro Carbamazepine
CAS :<p>Applications 10-Chloro Carbamazepine is a derivative of Carbamazepine (C175840) which is used in treatment of pain associated with trigeminal neuralgia.<br>References Stenger, E.G., et al.: Med. Exp., 11, 191 (1964), Pynnonen, S., et al.: Ther. Drug Monit., 1, 409 (1979), Sidebottom, A., et al.: J. Clin. Pharm. Ther., 20, 31 (1995)<br></p>Formule :C15H11ClN2OCouleur et forme :White PowderMasse moléculaire :270.71(2-Chlorophenyl)diphenylmethane
CAS :Produit contrôlé<p>Applications (2-Chlorophenyl)diphenylmethane is a triarylmethane with antiproliferative activity. (2-Chlorophenyl)diphenylmethane is an impurity of the antifungal agent Clotrimazole (C587400).<br>References Al-Qawasmeh, R.A. et al.: Bioorg. Med. Chem. Lett., 14, 347 (2004);<br></p>Formule :C19H15ClCouleur et forme :NeatMasse moléculaire :278.78(2Z)-2-[Cyano(2,3-dichlorophenyl)methylene]hydrazinecarboximidamide
CAS :Produit contrôléFormule :C9H7Cl2N5Couleur et forme :NeatMasse moléculaire :256.09(2R,3R)-3-(2,4-Difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl methanesulfonate
CAS :Produit contrôléFormule :C13H15F2N3O4SCouleur et forme :NeatMasse moléculaire :347.34(Chloromethyl)cyclohexane
CAS :Produit contrôlé<p>Applications (Chloromethyl)cyclohexane is a common chemical reagent used in the synthesis of imidazole inhibitors of cytokine release which suppresses the response to tumor necrosis factor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Laufer, S. et al., J. Med. Chem., 45, 1695 (2002); Rabinowitz, M. et al.: J. Med. Chem., 44, 4252 (2001);<br></p>Formule :C7H13ClCouleur et forme :NeatMasse moléculaire :132.63Isopropyl Itraconazole
CAS :Produit contrôléFormule :C34H36Cl2N8O4Couleur et forme :NeatMasse moléculaire :691.61N-Nitroso Albendazole (mixtures of regional isomers)
Produit contrôléFormule :C13H16N4O3SCouleur et forme :NeatMasse moléculaire :616.71210,11-Dihydro Carbamazepine
CAS :Produit contrôléFormule :C15H14N2OCouleur et forme :WhiteMasse moléculaire :238.28Nitroguanidine (Wetted with water >20%)
CAS :Produit contrôlé<p>Applications Nitroguanidine is used in the prediction of heats of detonation of energetic compounds from their molecular structure. It is also used in the synthetic preparation of imidacloprid-d4 (I274992), which is a neonicotinoid.<br> E0<br>References Keshavarz, M.H., et al.: Propellant, Explosives, Pyrotechnics, 37, 93 (2012); Chauzat, M., et al.: Env. Entomol., 38, 514 (2009), Patial, A., et al.: Env. Ecol., 27, 320 (2009), Fernandez-Bayo, J., et al.: J. Agric., Food Chem., 57, 5435 (2009), Tomizawa, M., et al.: J. Med. Chem., 52, 3735 (2009), Chem. and Eng. News 90: 10 (2012)<br></p>Formule :CH4N4O2Couleur et forme :White To Off-WhiteMasse moléculaire :104.07Lurasidone Opened Imide (Mixture of Diastereomers)
CAS :Produit contrôlé<p>Applications Lurasidone Opened Imide is an impurity in the synthesis of Lurasidone (L474920) which is antipsychotic used for treatment of schizophrenia.<br>References Ishiyama, T., et al.: Eur. J. Pharmacol., 572, 160 (2007); Cole, P., et al.: Drugs of the Fut., 33, 316 (2008);<br></p>Formule :C28H38N4O3SCouleur et forme :NeatMasse moléculaire :510.69ent-Voriconazole
CAS :Produit contrôlé<p>Impurity Voriconazole EP Impurity D; Voriconazole USP Related Compound B<br>Applications ent-Voriconazole (Voriconazole USP Related Compound B; Voriconazole EP Impurity D) is the (2S,3R) enantiomer in Voriconazole (V760000) drug substance.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gage, R., et al.: J. Pharm. Biomed. Anal., 17, 1449 (1998), Owens, P., et al.: Enantiomer, 4, 79 (1999), Pehourcq, F., et al.: Biomed. Chromatogr., 18, 719 (2004), Sellers, J., et al.: J. Pharm. Biomed. Anal., 41, 1088 (2006),<br></p>Formule :C16H14F3N5OCouleur et forme :NeatMasse moléculaire :349.31Itraconazole Desethylene-seco-piperazine Di-N-formyl Impurity
CAS :Produit contrôlé<p>Applications Itraconazole Desethylene-seco-piperazine Di-N-formyl Impurity is a by-product in the synthesis of Itraconazole Desethylene-seco-piperazine Mono-N-formyl Impurity (I937520), which is an impurity of Itraconazole (I937500). Itraconazole is an orally active antimycotic structurally related to Ketoconazole. Antifungal. It is a COVID19-related research product.<br>References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984), Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989), Sugar, A.M.,et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993),<br></p>Formule :C35H36Cl2N8O6Couleur et forme :NeatMasse moléculaire :735.624,4'-Dibromobenzophenone
CAS :Produit contrôlé<p>Applications 4,4'-Dibromobenzophenone is a reagent used in the synthesis of polyelectrolytes which serve as fluorescent visualizers for intracellular imaging with good biocompatibility.<br>References Hu, R., et al.: Chem. Asian J., 8, 2436-2445 (2013)<br></p>Formule :C13H8Br2OCouleur et forme :Yellow Orange To BrownMasse moléculaire :340.01Lormetazepam
CAS :Produit contrôlé<p>Applications An analog of Lorazepam (L469850). Sedative, hypnotic.Controlled substance (depressant).<br>References Nudelman, A., et al.: J. Pharma. Sci., 63, 1886 (1974), Humpel, M., et al.: Eur. J. Drug Metab. Pharmacokinet., 4, 237 (1979), Girkin, R., et al.: Xenobiotica, 10, 401 (1980),<br></p>Formule :C16H12Cl2N2O2Couleur et forme :Light Yellow To Light GreenMasse moléculaire :335.181-(1H-Benzo[d]imidazol-2-yl)-3-methyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid Sodium Salt
CAS :<p>Applications 1-(1H-Benzo[d]imidazol-2-yl)-3-methyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid is an impurity of Rabeprazole. It is also a degradation product formed in stressed tablets of Rabeprazole sodium.<br>References Kommanaboyina, B., et al.: Drug Dev. Ind. Pharm., 25, 857 (1999); Carswel, C., et al.: Drugs, 61, 2327 (2001); Garcia, C., et al.: J. Pharm. Biomed. Anal., 46, 88 (2008)<br></p>Formule :C14H10N3NaO3Couleur et forme :NeatMasse moléculaire :291.244,4'-(Bromomethylene)dibenzonitrile
CAS :Produit contrôlé<p>Applications 4,4'-(1-Bromomethyl)bis-benzonitrile (CAS# 69545-39-7) is a useful research chemical compound.<br></p>Formule :C15H9BrN2Couleur et forme :NeatMasse moléculaire :297.1493-Isobutylglutaric Anhydride
CAS :Produit contrôléFormule :C9H14O3Couleur et forme :NeatMasse moléculaire :170.2057trans-Itraconazole
CAS :Produit contrôlé<p>Impurity Itraconazole EP Impurity E<br>Applications trans-Itraconazole (Itraconazole EP Impurity E) is a geometrical isomer of Itraconazole (I937500). It is a COVID19-related research product.<br>References Ahn, C., et al.: J. Korean Chem. Soc., 43, 676 (1999),<br></p>Formule :C35H38Cl2N8O4Couleur et forme :NeatMasse moléculaire :705.63N-[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl] Rabeprazole Sulfide
CAS :Produit contrôlé<p>Applications Rabeprazole (R070500) N-aralkyl impurity.<br>References Fujisaki, H., et al.: Biochem. Pharmacol., 42, 321 (1991), Morri, M., et al.: J. Biol. Chem., 268, 21553 (1993), Pingili, R., et al.: Pharmazie, 60, 814 (2005),<br></p>Formule :C29H36N4O4SCouleur et forme :NeatMasse moléculaire :536.6910-Bromo-5H-dibenzo[b,f]azepine-5-carboxamide
CAS :Produit contrôlé<p>Impurity Carbamazepine EP Impurity G<br>Applications 10-Bromo-5H-dibenzo[b,f]azepine-5-carboxamide is a Carbamazepine (C175840(P)) impurity, which has been used in treatment of pain associated with trigeminal neuralgia. It is an anticonvulsant, neuroprotective & neuroresearch product.<br>References Cry, T., et. al.: J. Assoc. Official Anal. Chem., 70, 836 (1987); Stenger, E.G., et al.: Med. Exp., 11, 191 (1964); Pynnonen, S., et al.: Ther. Drug Monit., 1, 409 (1979); Sidebottom, A., et al.: J. Clin. Pharm. Ther., 20, 31 (1995)<br></p>Formule :C15H11BrN2OCouleur et forme :NeatMasse moléculaire :315.164,9-Diisobutyl-1,6-diazecane-2,7-dione
CAS :Produit contrôlé<p>Applications 4,9-Diisobutyl-1,6-diazecane-2,7-dione is in impurity of rac-Pregabalin (P704800) which is a GABA analogue used as an anticonvulsant.<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Formule :C16H30N2O2Couleur et forme :NeatMasse moléculaire :282.426-Chloro-2-methyl-4-(2-fluorophenyl)quinazoline
CAS :Produit contrôlé<p>Applications 6-Chloro-2-methyl-4-(2-fluorophenyl)quinazoline is a photochemical decomposition product of Midazolam (M343000), an anesthetic, anticonvulsant, sedative and hypotic agent.<br>References Anderson, R., et al.: J. Pharma. Biomed. Anal., 13, 667 (1995); Anderson, R., et al: Am. Clin. Lab., 16, 25 (1997);<br></p>Formule :C15H10ClFN2Couleur et forme :NeatMasse moléculaire :272.702,5-Dichlorothiophen-3-yl Tioconazole Hydrochloride
CAS :Produit contrôléFormule :C16H12Cl4N2OS·ClHCouleur et forme :NeatMasse moléculaire :458.62Prazepam-d5
CAS :Produit contrôlé<p>Applications Prazepam-d5, is the labeled analogue of Prazepam (P702250), a benzodiazepine derivative drug having anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties.<br>References Shader R. I., et al.: Ciba. Found. Symp., (74), 141 (1979); Jacqmin, P., et al.: Neuropsychobiology, 19 (4), 186 (1988);<br></p>Formule :C192H5H12ClN2OCouleur et forme :NeatMasse moléculaire :329.831',4-Dihydroxy Midazolam
CAS :Produit contrôlé<p>Applications A metabolite of Midazolam (M343000).<br>References Soucek, P., et al.: Xenobiotica, 22, 83 (1992), Ghosal, A., et al.: Drug Metab. Dispos., 24, 940 (1996), Kobayashi, K., et al.: Biochem. Pharmacol., 63, 889 (2002),<br></p>Formule :C18H13ClFN3O2Couleur et forme :NeatMasse moléculaire :357.77Varenicline-d2,15N2 Dihydrochloride
CAS :Produit contrôlé<p>Applications Varenicline-d2,15N2 Dihydrochloride, is the labelled dihydrochloride salt of Varenicline (V098492), a nicotinic α4β2 acetylcholine receptor partial agonist. Aids in smoking cessation.<br>References Benowitz, N., et al.: Clin. Pharmacol. Ther., 44, 23 (1988), Cohen, C., et al.: J. Pharmacol. Exp. Ther., 306, 407 (2003), Tapper, A., et al.: Science, 306, 1029 (2004), Coe, J., et al.: J. Med. Chem., 48, 3474 (2005), Obach, R., et al.: Drug Metab. Disp., 34, 121 (2006),<br></p>Formule :C13H13D2Cl2N15N2Couleur et forme :Light Beige SolidMasse moléculaire :288.18Metopimazine
CAS :<p>Applications Metopimazine (MPZ) is used to prevent emesis during chemotherapies. Antiemetic.<br>References Catz, P., et al.: Int. J. Pharm., 58, 93 (1990), Sato, K., et al.: J. Pharm. Sci., 80, 104 (1991), Herrstedt, J., et al.: Cancer Chemother. Pharmacol., 33, 53 (1996), Sigsgaard, T., et al.: J. Clin. Onc., 19, 2091 (2001),<br></p>Formule :C22H27N3O3S2Couleur et forme :Off White SolidMasse moléculaire :445.60N-Methyl Omeprazole-d3 (Mixture of isomers with the methylated nitrogens of imidazole)
CAS :Produit contrôlé<p>Applications Labelled Omeprazole (O635000) impurity.<br>References Allenmark, S., et al.: Anal. Biochem., 136, 293 (1984), Besancon, M., et al.: J. Biol. Chem., 272, 22438 (1997),<br></p>Formule :C18H18D3N3O3SCouleur et forme :NeatMasse moléculaire :362.46rac N-Demethyl Promethazine-d3 Hydrochloride
CAS :Produit contrôlé<p>Applications Labelled Promethazine (P757000) impurity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Keipert, S., et al.: Pharmazie, 31, 296 (1976),<br></p>Formule :C16H16D3ClN2SCouleur et forme :NeatMasse moléculaire :309.87N-Desmethyl Dextrorphan β-D-O-Glucuronide
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications A labelled metabolite of Dextromethorphan.<br>References Gonzalez, F., et al.: Nature, 331, 442 (1988), Chen, S., et al.: Clin. Pharmacol. Ther., 60, 522 (1996), Hartter, S., et al.: Ther. Drug Monit., 18, 297 (1996), Garcia-Martin, E., et al.: Clin. Pharmacol. Ther., 71, 196 (2002),<br></p>Formule :C22H29NO7Couleur et forme :NeatMasse moléculaire :419.47
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