Dérivés des Purines et Pyrimidines
Les purines possèdent une structure bicyclique, composée d’un cycle à six membres fusionné avec un cycle à cinq membres, tous deux contenant des atomes d’azote à des positions clés. Les dérivés des purines, tels que l’adénine et la guanine, sont essentiels à la formation de l’ADN et de l’ARN. Ces composés ont des applications thérapeutiques dans le traitement du cancer et des maladies virales en inhibant la réplication cellulaire. Les pyrimidines, quant à elles, possèdent une structure monocyclique à six membres avec deux atomes d’azote. Leurs dérivés, tels que la cytosine, la thymine et l’uracile, sont également des composants essentiels de l’ADN et de l’ARN et sont utilisés en chimiothérapie et dans les traitements antiviraux.
Chez CymitQuimica, nous proposons des dérivés des purines et pyrimidines pour la recherche en biologie moléculaire, génomique et le développement de thérapies innovantes.
8895 produits trouvés pour "Dérivés des Purines et Pyrimidines"
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1-Methyl-nicotinamide Iodide
CAS :Produit contrôlé<p>Applications A nicotinic acid derivative which shows a dopaminergic neurotoxicity.<br>References Rollema, H., et al.: J. Med. Chem., 33, 2221 (1990),<br></p>Formule :C7H9IN2OCouleur et forme :NeatMasse moléculaire :264.064-Hydroxythiobenzamide
CAS :<p>Applications 4-Hydroxythiobenzamide is used in the synthesis of PPARα agonists used in increasing HDLc levels. Also used in the synthesis of potent CDK5 inhibitors in the treatment of Alzheimer’s disease.<br>References Sierra, M. et al.: J. Med. Chem., 50, 685 (2007); Zhong, W. et al.: Bioorg. Med. Chem. Lett., 17, 5384 (2007);<br></p>Formule :C7H7NOSCouleur et forme :NeatMasse moléculaire :153.2Didesmethyl Zolmitriptan (90%)
CAS :Produit contrôlé<p>Applications A metabolite of Zolmitriptan (Z639000).<br>References Buckingham, J., et al.: J. Med. Chem., 38, 3566 (1995),<br></p>Formule :C14H17N3O2Degré de pureté :90%Couleur et forme :NeatMasse moléculaire :259.30Iso Rizatriptan
CAS :Produit contrôlé<p>Impurity Rizatriptan EP Impurity C<br>Applications Iso Rizatriptan (Rizatriptan EP Impurity C) is a potential impurity of Rizatriptan. A regioisomer of Rizatriptan.<br>References Dill, K., et al.: J. Phys. Chem., 91, 1980 (1987), Cole, L., et al.: Anal. Chem., 64, 1317 (1992), Street, L., et al.: J. Med. Chem., 1995, 38, 1799<br></p>Formule :C15H19N5Couleur et forme :NeatMasse moléculaire :269.34Telbivudine
CAS :Produit contrôlé<p>Applications Nucleoside analog; specific inhibitor of hepatitis B virus (HBV) replication. Antiviral.<br>References Standring, D.N., et al.: Antiviral. Chem. Chemother., 12, 119 (2001), Hernandez-Santiago, B., et al.: Antimicrob. Agents Chemother., 46, 1728 (2002), Lai, C.-L., et al.: Hepatology, 40, 719 (2004), Han, S.-H.B., et al.: Expert Opin. Invest. Drugs, 14, 511 (2005),<br></p>Formule :C10H14N2O5Couleur et forme :White To Off-WhiteMasse moléculaire :242.231,2,3-Triphenylguanidine
CAS :Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :287.3659973144531Chloromethyl Methyl Carbonate
CAS :Produit contrôlé<p>Applications A reagent used in the preparation of prodrugs of diacidic nonpeptide angiotensin II antagonist as well as pyrrolothiazole platelet activating factor antagonist.<br>References Aungst, B.J. et al.: Pharmac. Res., 12, 763 (1996); Davidsen, S.K. et al.: J. Med. Chem., 37, 4423 (1994);<br></p>Formule :C3H5ClO3Couleur et forme :NeatMasse moléculaire :124.52L-Aspartyl-L-phenylalanine Hydrochloride
CAS :Produit contrôlé<p>Applications L-Aspartyl-L-phenylalanine is an impurity of Thiamine (T344185). Thiamine Impurity B.<br>References Aluwihare, L., et al.: Science, 308, 1007 (2005), Koch, B., et al.: Anal. Chem., 79, 1758 (2007), Reemtsma, T., et al.: Environ. Sci. Technol., 42, 1430 (2008),<br></p>Formule :C13H16N2O5xHClCouleur et forme :NeatMasse moléculaire :280.28Sumatriptan Succinate
CAS :Produit contrôlé<p>Applications Sumatriptan Succinate is a selective 5-HT1B/1D-receptor agonist with anticonvulsant properties (1,2). Sumatriptan Succinate is used for migraine relief (2).<br>References (1) Razzaque, Z., et al.: Br J Clin Pharmacol. 47, 75 (1999) (2) Cady, R. K., et al.: J Headache Pain. 18, 17 (2017)<br></p>Formule :C14H21N3O2S·C4H6O4Couleur et forme :White To Off-WhiteMasse moléculaire :413.492-Hydrazino Adenosine
CAS :Produit contrôlé<p>Stability Moisture Sensitive<br>Applications A useful synthetic intermediate for making potent and selective coronary vasodilators.<br>References Niiya, K., et al.: J. Med. Chem., 35, 4557 (1992)<br></p>Formule :C10H15N7O4Couleur et forme :NeatMasse moléculaire :297.27Caffeine-d3 (7-methyl-d3)
CAS :Produit contrôlé<p>Applications Caffeine-d3 (7-methyl-d3) (CAS# 26351-04-2) is a useful isotopically labeled research compound.<br></p>Formule :C8D3H7N4O2Couleur et forme :White To Off-WhiteMasse moléculaire :197.209Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate
CAS :<p>Applications Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate is an impurity of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.<br>References Vallu, V., et. al.: Anal. Chem. Indian J., 14, 339 (2014); Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)<br></p>Formule :C18H20N2O3SCouleur et forme :NeatMasse moléculaire :344.43Iopamidol-D3
CAS :Produit contrôlé<p>Applications Labelled nonionic radiocontrast medium. Diagnostic aid (radiopaque medium).<br>References Drayer, B., et al.: Am. J. Neuroradiol., 3, 59 (1982), Molyneux, A.J., et al.: Br. J. Radiol., 55, 117 (1982), Sovak, M., et al.: Radiology, 142, 115 (1982), Felder, E., et al.: Anal. Profiles Drug Subs., 17, 115 (1988),<br></p>Formule :C17H19D3I3N3O8Couleur et forme :Off-WhiteMasse moléculaire :780.104-(6-BROMOINDOLIN-1-YL)PYRIMIDIN-2-AMINE HCL
Degré de pureté :95.0%Masse moléculaire :327.60998535156253-(Formylamino)-1H-pyrazole-4-carboxamide
CAS :Produit contrôlé<p>Impurity Allopurinol EP Impurity B / Allopurinol USP Related Compound B<br>Stability Hygroscopic<br>Applications 3-(Formylamino)-1H-pyrazole-4-carboxamide (Allopurinol EP Impurity B) is an impurity of Allopurinol (A547300) with inhibitory effects on human hypoxanthine phosphoribosyltransferase.<br>References Krenitzky, T.A. et al.: J. Biol. Chem., 244, 1263 (1969);<br></p>Formule :C5H6N4O2Couleur et forme :White To Off-WhiteMasse moléculaire :154.127(6-Methoxy-2-methylsulfanyl-pyrimidin-4-yl)-piperidin-4-yl-amine hydrochloride
CAS :Degré de pureté :95.0%Masse moléculaire :290.809997558593751,2,3,9-Tetrahydro-3-(1H-imidazol-1-ylmethyl)-9-methyl-4H-carbazol-4-one (Ondansetron Impurity G)
CAS :Produit contrôlé<p>Applications 1,2,3,9-Tetrahydro-3-(1H-imidazol-1-ylmethyl)-9-methyl-4H-carbazol-4-one is an metabolite of Ondansetron (O655000), is a selective 5-hydroxytryptamine3 (5-HT3) receptor antagonist that has been introduced to clinical practice as an antiemetic for cancer treatment-induced and anesthesia-related nausea and vomiting.<br>References Kris, M.G., et al.: J. Clin. Oncol., 6, 659 (1988), Faris, P..L., et al.: Lances, 355, 792 (2000), Ye, J.H., et al.: CNS Drug Reviews., 7, 199 (2001);<br></p>Formule :C17H17N3OCouleur et forme :White To Off-WhiteMasse moléculaire :279.342-Amino-5-ethynylpyrimidine
CAS :Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :119.12699890136719Orotic Acid-15N2 Monohydrate
CAS :<p>Applications Orotic Acid-15N2 Monohydrate is a labelled analogue of Orotic Acid Monohydrate (O691500(P)), which is used in the preparation of therapeutic agents for chronic obstructive pulmonary disease (COPD) treatment.<br>References Furukawa, S.: PCT Int. Appl. (2009), WO 2009069291 A1<br></p>Formule :C5H415N2O4·H2OCouleur et forme :NeatMasse moléculaire :177.09Methotrexate a-Methyl Ester (>90%)
CAS :Produit contrôlé<p>Impurity Methotrexate EP Impurity I<br>Applications Methotrexate α-methyl ester is an impurity of Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),<br></p>Formule :C21H24N8O5Degré de pureté :>90%Couleur et forme :NeatMasse moléculaire :468.471,3,5-Trimethyladamantane
CAS :Produit contrôlé<p>Applications An alkyladamantane derivative that are biotransformed via strains of Pseudomonas. It is used to study alkyladamantane adsorption on graphitized thermal carbon black.<br>References Yashkin, S.N. et al.: Rus. Che,. Bull., 57, 2472 (2008); Slepen’kin, A. et al.: Nefeckhim., 33, 406 (1993);<br></p>Formule :C13H22Couleur et forme :NeatMasse moléculaire :178.31Methotrexate-d3
CAS :Produit contrôlé<p>Applications Labelled Methotrexate (M260675). A Folic acid antagonist. Used as a antineoplastic and antirheumatic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),<br></p>Formule :C20H19D3N8O5Couleur et forme :NeatMasse moléculaire :457.464-(3,4-dimethylphenyl)-6-(3-methoxyphenyl)pyrimidin-2-amine
CAS :Degré de pureté :95.0%Masse moléculaire :305.3810119628906Pirimiphos-methyl, 90%
CAS :Produit contrôlé<p>Applications Pirimiphos-methyl is a phosphorothioate used as an insecticide. Pirimiphos-methyl is commonly used for mosquito control as well as control of greenhouse crop pests and stored-product insects.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Deighton, J. et al.: Mosq. News, 34, 163 (1974); LaHue, D.W.: J. Econ. Entomol., 68, 236 (1975); Antonious, G.F. et al.: J. Entomol. Sci., 30, 191 (1995):<br></p>Formule :C11H20N3O3PSDegré de pureté :90%Couleur et forme :ColourlessMasse moléculaire :305.331,7-Dimethyluric Acid
CAS :Produit contrôlé<p>Applications A metabolite of Caffeine.<br>References Kalow, W., et al.: Clin. Pharmacol. Ther., 53, 503 (1993), Sharma, S., et al.: Cancer Res., 54, 5848 (1994), Sugawara, M., et al.: J. Biol. Chem., 275, 16473 (2000), Takeda, M., et al.: J. Pharmacol. Exp. Ther., 302, 666 (2002),<br></p>Formule :C7H8N4O3Couleur et forme :NeatMasse moléculaire :196.164-(Chloromethyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide
CAS :Degré de pureté :95+%Masse moléculaire :429.9100036621094N-(4-((4-Chloro-6-((5-methyl-1H-pyrazol-3-yl)amino)pyrimidin-2-yl)thio)phenyl)cyclopropanecarboxamide
CAS :Degré de pureté :95.0%Masse moléculaire :400.8900146484375N-(4-Fluorobenzyl)-2-((R)-5-(3-methylureido)-2',4'-dioxo-2,3-dihydrospiro[indene-1,5'-oxazolidin]-3'-yl)-N-((S)-1,1,1-trifluoropropan-2-yl)acetamide
CAS :Degré de pureté :97.0%Masse moléculaire :536.1682827488-Descarboxamido-8-cyano Temozolomide
CAS :Produit contrôlé<p>Applications 8-Descarboxamido-8-cyano Temozolomide is a useful synthetic intermediate in the synthesis of Temozolomide (T017775); an imidazotetrazine alkylating agent and antineoplastic.<br>References Newlands, E.S., et al.: Cancer Treat. Rev., 23, 35 (1997); Kim, C., et al.: J. Biol. Chem., 274, 1233 (1999); Hait, W., et al.: Cancer Res., 69, 1263 (2009); Wang, Y., et al.: J. Org. Chem., 62, 7288 (1997)<br></p>Formule :C6H4N6OCouleur et forme :Light Yellow To Light BrownMasse moléculaire :176.14(6R)-5,6,7,8-Tetrahydrobiopterin Dihydrochloride
CAS :<p>Stability Hygroscopic<br>Applications Tetrahydrobiopterin is a naturally occurring essential cofactor of the three aromatic amino acid hydroxylase enzymes, used in the degradation of amino acid phenylalanine and in the biosynthesis of the neurotransmitters serotonin, melatonin, dopamine, norepinephrine , epinephrine, and is a cofactor for the production of nitric oxide by the nitric oxide synthases. Chemically, its structure is that of a reduced pteridine derivative.<br>References Levy, Harvey L., et al.: Lancet, 370, 504 (2007); Isojima, Yasushi., et al.: Proc Natl Acad Sci USA .,106, 15744 (2009); Burton, B. K., et al.: J. Inherit. Metab. Dis., 30, 700 (2007)<br></p>Formule :C9H15N5O3·2(HCl)Couleur et forme :White To Off-WhiteMasse moléculaire :241.25 + 2(36.46)Febuxostat-d7
CAS :Produit contrôlé<p>Applications Febuxostat-d7, is the labeled analogue of Febuxostat-d7 (F229000), a Xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout.<br>References Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993), Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003), Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005), Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005),<br></p>Formule :C16H9D7N2O3SCouleur et forme :NeatMasse moléculaire :323.422-Chloro-N-piperidin-4-ylpyrimidin-4-amine hydrochloride
CAS :Degré de pureté :97.0%Masse moléculaire :249.139999389648443-Nitropyridine
CAS :Produit contrôlé<p>Applications Used in the novel synthesis of biologically active nitro heterocyclic compounds.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pawar, N., et al.: Eur. J. Pharm. Sci., 21, 115 (2004), Badgujar, D., et al.: J. Sci. Ind. Res., 66, 250 (2007),<br></p>Formule :C5H4N2O2Couleur et forme :NeatMasse moléculaire :124.102-Fluoroadenosine
CAS :Produit contrôlé<p>Applications 2-Fluoroadenosine is a fluorinated analog of Adenoside (A280400) nucleotide.<br>References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010); Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010);<br></p>Formule :C10H12FN5O4Couleur et forme :NeatMasse moléculaire :285.236-(4-CHLOROPHENYL)-2-METHYLPYRIMIDIN-4-AMINE
CAS :Degré de pureté :95.0%Masse moléculaire :219.6699981689453Tenofovir Monohydrate
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Tenofovir Monohydrate is an HIV-1 RT inhibitor and antiretroviral drug.<br>References Zhao, Z., et al.: Method for preparing medical salts and/or derivatives of tenofovir disoproxil, and their application for preventing and/or treating HBV and HIV/AIDS infections, CN 101574356 (2009);<br></p>Formule :C9H14N5O4P·H2OCouleur et forme :NeatMasse moléculaire :305.23Methyl 4-((6-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidin-4-yl)oxy)benzoate
CAS :Degré de pureté :97.0%Masse moléculaire :324.33999633789065-{[(4,6-dimethylpyrimidin-2-yl)thio]methyl}-4-(4-fluorophenyl)-4H-1,2,4-triazole-3-thiol
CAS :Degré de pureté :95.0%Masse moléculaire :347.067465668Paraxanthine-d3
CAS :Produit contrôlé<p>Applications Paraxanthine-d3, is the labeled analogue of Paraxanthine (P192500), an adenosine receptor ligand and a major metabolite of caffeine.<br>References Proc. Natl. Acad. Sci. USA 78, 3260 (1981); Cell Mol. Neurobiol., 3, 69 (1983); Eur. J. Pharmacol., 179, 295 (1990)<br></p>Formule :C72H3H5N4O2Couleur et forme :NeatMasse moléculaire :183.181,3-Dimethyladamantane
CAS :<p>Impurity Memantine Related Compound A (1,3-Dimethyladamantane)<br>Applications 1,3-Dimethyladamantane is a dimethylated adamantane derivative. Memantine impurity A. Memantine Related Compound A (1,3-Dimethyladamantane).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formule :C12H20Couleur et forme :NeatMasse moléculaire :164.29Ethyl 2-Chloracetoacetate
CAS :<p>Applications Ethyl 2-Chloracetoacetate is used in the preparation of oxazoles and thiazoles as agonists for peroxisome proliferator-activated receptor δ. It is also used to synthesize dimethylimidazothiadiazolecarbohydrazides with anticancer activities.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sznaidman, M., et al.: Bioorg. Med. chem. Lett., 13, 1517 (2003); Terzioglu, N., et al.: Eur. J. Med. Chem., 38, 781 (2003)<br></p>Formule :C6H9ClO3Couleur et forme :NeatMasse moléculaire :164.594-(2,4-dimethoxyphenyl)-6-(3,4-dimethylphenyl)pyrimidin-2-amine
CAS :Degré de pureté :95.0%Masse moléculaire :335.4070129394531N'-Methyl-N,N-diphenylurea
CAS :<p>Impurity Temozolomide USP Related Compound B<br>Applications N'-Methyl-N,N-diphenylurea is used in the stabilization of thermal propellants. Temozolomide USP Related Compound B.<br>References Bohn, M. et al.: Prop. Exp. Pyro.,et al.: 19, 266 (1994); Muthurajan, H. et al.: J. Hazard. Mat., 133, 30 (2006);<br></p>Formule :C14H14N2OCouleur et forme :NeatMasse moléculaire :226.276-CHLORO-1-(4-METHOXYBENZYL)-3-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE
CAS :Degré de pureté :95.0%Masse moléculaire :280.7099914550781Chloromethyl Propyl Carbonate
CAS :Produit contrôlé<p>Applications Chloromethyl Propyl Carbonate (cas# 35273-90-6) is a compound useful in organic synthesis.<br></p>Formule :C5H9ClO3Couleur et forme :Colourless OilyMasse moléculaire :152.583,5,3',5'-Tetraiodo Thyrolactic Acid (~90%)
CAS :Produit contrôlé<p>Stability Hygroscopic, Temperature sensitive<br>Applications 3,5,3',5'-Tetraiodo Thyrolactic Acid is a thyroid hormone analogue. A Thyroxine (T425600) analogue.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Horst, C., et al.: Biochem. J., 261, 945 (1989); Kvetny, J., et al.: Horm. Metab. Res., 24, 322 (1992); Yamauchi, K., et al.: J. Biol. Chem., 274, 8460 (1999); Davis, P., et al.: J. Endocrinol. Invest., 25, 377 (2002);<br></p>Formule :C15H10I4O5Degré de pureté :~90%Couleur et forme :BeigeMasse moléculaire :777.851-Methyluric Acid-d3
CAS :Produit contrôlé<p>Applications A labelled metabolite of Theophylline.<br>References Chen, Y., et al.: Clin. Exper. Pharmacol. Physiol., 36, 828 (2009), Yu, C., et al.: J. Bacteriol., 191, 4624 (2009), Jetter, A., et al.: Eur. J. Clin. Pharmacol., 65, 411 (2009),<br></p>Formule :C62H3H3N4O3Couleur et forme :NeatMasse moléculaire :185.16N-Demethyl Ondansetron
CAS :<p>Applications A metabolite of Ondansetron (O655000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bayliss, M., et al: Xenobiotica, 24, 231 (1994), Atkins, W., et al.: J. Biol. Chem., 277, 33258 (2002), De Graaf, I., et al.: Drug Metab. Dispos., 30, 1129 (2002),<br></p>Formule :C17H17N3OCouleur et forme :White To BrownMasse moléculaire :279.344-([1,1'-Biphenyl]-4-yl)-6-chloro-2-phenylpyrimidine
CAS :Degré de pureté :95.0%Masse moléculaire :342.8299865722656N,N'-Di-Boc-guanidine
CAS :Degré de pureté :99.0%Couleur et forme :Solid, Crystalline Powder or PowderMasse moléculaire :259.30599975585943-Descyano Febuxostat
CAS :Produit contrôlé<p>Applications 3-Descyano Febuxostat is an impurity of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.<br>References Kadivar, M.H., et. al.: J. Pharmaceut. Biomed. Anal., 56, 749 (2011); Vallu, V., et. al.: Anal. Chem. Indian J., 14, 339 (2014); Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)<br></p>Formule :C15H17NO3SCouleur et forme :NeatMasse moléculaire :291.371-(3-(BENZO[D]THIAZOL-2-YL)-4-HYDROXYPHENYL)-3-PHENYLUREA
CAS :Degré de pureté :95.0%Masse moléculaire :361.42001342773444-(Benzylamino)-2-((3-chloro-4-hydroxyphenethyl)amino)pyrimidine-5-carboxamide
CAS :Degré de pureté :95.0%Masse moléculaire :397.85998535156252,4,6-Trichloro-5-(4-chlorophenyl)pyrimidine
CAS :Degré de pureté :98%Masse moléculaire :293.95999145507814-(6-o-Tolyl-pyridin-3-yl)-pyrimidin-2-ylamine
Degré de pureté :95.0%Masse moléculaire :262.31600952148446-Methyl-2-(pyridin-4-yl)pyrimidin-4(3H)-one
CAS :Degré de pureté :95.0%Masse moléculaire :187.20199584960938N4-(Benzo[d][1,3]dioxol-5-ylmethyl)-6-(3-methoxyphenyl)pyrimidine-2,4-diamine
CAS :Degré de pureté :95.0%Masse moléculaire :350.37799072265625Ref: 10-F431587
5mgÀ demander10mgÀ demander25mgÀ demander50mgÀ demander100mgÀ demander250mgÀ demanderFmoc N-Hydroxysuccinimide Ester
CAS :<p>Stability Moisture Sensitive<br>Applications Used in conjunction with Isothiocyanate to conduct partial Edman Degradation on biologically active peptides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Heidenreich, O., et al.: J. Biol. Chem., 269, 2131 (1994), Kothe, U., et al.: Anal. Biochem., 356, 148 (2006), Thakkar, A., et al.: Anal. Chem., 78, 5935 (2006),<br></p>Formule :C19H15NO5Couleur et forme :NeatMasse moléculaire :337.33Tenofovir Diphosphate Triethylamine Salt (Mixture of Diastereomers)
CAS :<p>Stability Very Hygroscopic<br>Applications A metabolite of Tenofovir (T018500).<br>References Hazra, R., et al.: Antimicrob. Agents Chemother., 48, 124 (2004), Piketty, C., et al.: Antivir. Ther., 11, 213 (2006), Molto, J., et al.: Ther. Drug Monit., 29, 648 (2007),<br></p>Formule :C9H16N5O10P3·C6H15NCouleur et forme :Off-White To Light YellowMasse moléculaire :447.17(3aS,4S,6R,6aR)-6-(6-Amino-2-chloro-9H-purin-9-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole-4-carboxylic acid
CAS :Degré de pureté :97.0%Masse moléculaire :355.739990234375(E)-N-(4-(N-(4,6-dimethylpyrimidin-2-yl)sulfamoyl)phenyl)-3-(p-tolyl)acrylamide
CAS :Degré de pureté :98%Masse moléculaire :422.5[1-(5-Bromopyrimidin-2-yl)piperidin-3-yl]methanol
CAS :Degré de pureté :95.0%Masse moléculaire :272.14599609375Methyl 2-(2-((6-(2-cyanophenoxy)pyrimidin-4-yl)oxy)phenyl)acetate
CAS :Degré de pureté :98%Masse moléculaire :361.356994628906253-Descyano-3-formyl Febuxostat
CAS :Formule :C16H17NO4SCouleur et forme :NeatMasse moléculaire :319.382-Mercapto-3-methyl-3H-purin-6(9H)-one
CAS :Degré de pureté :97.0%Masse moléculaire :182.19999694824227-BROMO-2-(3-(PYRIMIDIN-2-YL)PHENETHYL)ISOINDOLIN-1-ONE
CAS :Degré de pureté :95.0%Masse moléculaire :394.27200317382812,4-Pteridinediamine-6-methanol
CAS :Produit contrôléFormule :C7H8N6OCouleur et forme :NeatMasse moléculaire :192.186-Amino-1,3-dipropyl-5-nitrosouracil
CAS :Produit contrôlé<p>Stability Stable at RT<br>Applications An intermediate used for the sythesis of xanthine derivatives.<br>References Daly, J.W., et al.: J. Med. Chem., 28, 487 (1985), Erickson, R.H., et al.: J. Med. Chem., 34, 3405 (1991),<br></p>Formule :C10H16N4O3Couleur et forme :NeatMasse moléculaire :240.265-Acetylamino-6-formylamino-3-methyluracil
CAS :Produit contrôlé<p>Applications Metabolite of Caffeine (C080100).<br>References Grant, D.M., et al.: Clin. Pharm. and Ther., 33, 591 (1983),<br></p>Formule :C8H10N4O4Couleur et forme :Light Yellow SolidMasse moléculaire :226.196-CHLORO-9-(2-FLUOROBENZYL)-9H-PURINE
CAS :Degré de pureté :95.0%Masse moléculaire :262.67001342773445-Bromo-N-(diphenylmethylene)-2-pyrimidinamine
CAS :Degré de pureté :95+%Masse moléculaire :338.2080078125Doxofylline
CAS :Produit contrôlé<p>Applications Doxofylline is a xanthine molecule that appears to be both bronchodilator and anti-inflammatory with an improved therapeutic window over conventional xanthines such as Theophylline and the evidence supporting the effects of Doxofylline in the treatment of lung diseases.<br>References Franzone, J., et al.: Drugs Exp. Clin. Res., 14, 479 (1988), Nicholson, C., et al.: Pulm. Pharmacol., 7, 1 (1994), Sullivan, P., et al.: Lancet, 343, 1006 (1994),<br></p>Formule :C11H14N4O4Couleur et forme :NeatMasse moléculaire :266.256-Amino-1-propyl-1H-pyrimidine-2,4-dione
CAS :Degré de pureté :95%Masse moléculaire :169.18400573730475-Cyclopropyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one
CAS :Formule :C7H8N2OSDegré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :168.21N4-Methylene Zolmitriptan
CAS :Produit contrôlé<p>Applications Zolmitriptan (Z639000) impurity.<br></p>Formule :C17H21N3O2Couleur et forme :NeatMasse moléculaire :299.374-(6-p-Tolyl-pyridin-3-yl)-pyrimidin-2-ylamine
Degré de pureté :95.0%Masse moléculaire :262.31600952148442-(5-amino-3-cyclopropyl-1H-pyrazol-1-yl)-5-ethyl-6-methylpyrimidin-4(3H)-one
CAS :Degré de pureté :95.0%Masse moléculaire :259.312988281257-Hydroxy DAMPA
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications A metabolite of DAMPA.<br>References Bleyer, W., et al.: Cancer, 41, 36 ( 1978), Abelson, H., et al.: J. Clin. Oncol., 1, 208 (1983), Fabre, G., et al.: Biochem. Pharmacol., 35, 1325 (1986), Widemann, B., et al.: Clin. Chem., 45, 223 (1999),<br></p>Formule :C15H15N7O3Couleur et forme :YellowMasse moléculaire :341.324-Dimethylaminobutyraldehyde Diethyl Acetal
CAS :Produit contrôlé<p>Impurity Zolmitriptan USP Related Compound H<br>Applications 4-Dimethylaminobutyraldehyde Diethyl Acetal (Zolmitriptan USP Related Compound H) is used in the preparation of N,N-Dimethyltryptamines, 5-HT1D receptor agonists, for medicinal treatments such as antimigraine drugs.<br>References Chen, C. et al.: J. Org. Chem., 59, 3738 (1994);<br></p>Formule :C11H23NO2Couleur et forme :NeatMasse moléculaire :189.34-(Imidazo[1,2-a]pyridin-3-yl)pyrimidin-2-amine
CAS :Degré de pureté :95+%Masse moléculaire :211.22799682617188N-[[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]hydroxyphosphinyl]-D-alanine 1-Methylethyl Ester
CAS :Produit contrôlé<p>Applications N-[[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]hydroxyphosphinyl]-D-alanine 1-Methylethyl Ester prorug of PMPA, phenyl monophosphoramidate, and is a Tenofovir (T018500) derivative, an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007), Lee, W. et al.: Antimicrob. Agents Chemother., 49, 1898 (2005);<br></p>Formule :C15H25N6O5PDegré de pureté :>85%Couleur et forme :NeatMasse moléculaire :400.37N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-3-methylbenzamide
CAS :Masse moléculaire :396.4700012207031MTIC-d3
CAS :Produit contrôlé<p>Applications A labelled metabolite of Temozolomide, an antineoplastic.<br></p>Formule :C5H5D3N6OCouleur et forme :Off White SolidMasse moléculaire :171.18N2-ISOBUTYRYL-2'-O-METHYL-GUANOSINE
CAS :Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :367.361999511718754-(2H-1,3-benzodioxol-5-yl)-6-(3,4-dimethylphenyl)pyrimidin-2-amine
CAS :Degré de pureté :95.0%Masse moléculaire :319.3640136718754-(3,4-dimethylphenyl)-6-(2-fluorophenyl)pyrimidin-2-amine
CAS :Degré de pureté :95.0%Masse moléculaire :293.34500122070312-Methylimidazole
CAS :<p>Applications 2-Methylimidazole is a monomethylated imidazole that can be used as a building block in the preparation of a wide range of biologically active compounds. 2-Methylimidazole as well as other imidazoles can be use as catalyst for refolding of enhanced coloured fluorescent protein. 2-Methylimidazole has been identified as a byproduct of fermentation and is detected in foods and mainstream and side-stream tobacco smoke.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shi, R. et al.: Arch. Biochem. Biophys., 459, 122 (2007); Chan, P.C. et al.: Arch. Toxicol., 82, 399 (2008); Nishie, K. et al.: Toxicol. Appl. Pharmacol., 14, 301 (1969);<br></p>Formule :C4H6N2Couleur et forme :NeatMasse moléculaire :82.104-Ethoxy-3-(3-pyridin-2-yl-ureido)benzenesulfonyl chloride
CAS :Formule :C14H14ClN3O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :355.79Theophylline-13C2d6
CAS :Produit contrôlé<p>Applications Labelled Theophylline is a xanthine derivative with diuretic, cardiac stimulant and smooth muscle relaxant activities; isomeric with theobromine. Small amounts occur in tea. Bronchodilator.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cohen, J.L., et al.: Anal. Profiles Drug Subs., 4, 466 (1975), Svedmyr, K., et al.: Allergy, 37, 111 (1982),<br></p>Formule :C513C2H2D6N4O2Couleur et forme :NeatMasse moléculaire :188.19Mono-POC Tenofovir
CAS :<p>Stability Hygroscopic<br>Applications An impurity of Tenofovir Disoproxil (T018505(P)), which is an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. It is used as an anti-HIV agent and an antiviral.<br>References Gan, L., et al.: Drug Metab. Dispos., 24, 344 (1996), Annaert, P., et al.: Pharm. Res., 14, 492 (1997), Naesens, L., et al.: Antimicrob. Agents Chemother., 42, 1568 (1998), Shaw, J. P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007)<br></p>Formule :C14H22N5O7PCouleur et forme :White To Light BeigeMasse moléculaire :403.33Febuxostat
CAS :<p>Applications Xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.<br>References Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993), Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003), Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005), Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005),<br></p>Formule :C16H16N2O3SCouleur et forme :White To Off-WhiteMasse moléculaire :316.376-Bromo-3-(2-chloro-5-(trifluoromethyl)pyrimidin-4-yl)-1-(phenylsulfonyl)-1H-indole
CAS :Degré de pureté :97%Masse moléculaire :516.7199707031254-(3-bromophenyl)-6-(3,4-dimethylphenyl)pyrimidin-2-amine
CAS :Degré de pureté :95.0%Masse moléculaire :354.2510070800781
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