Dérivés des Purines et Pyrimidines
Les purines possèdent une structure bicyclique, composée d’un cycle à six membres fusionné avec un cycle à cinq membres, tous deux contenant des atomes d’azote à des positions clés. Les dérivés des purines, tels que l’adénine et la guanine, sont essentiels à la formation de l’ADN et de l’ARN. Ces composés ont des applications thérapeutiques dans le traitement du cancer et des maladies virales en inhibant la réplication cellulaire. Les pyrimidines, quant à elles, possèdent une structure monocyclique à six membres avec deux atomes d’azote. Leurs dérivés, tels que la cytosine, la thymine et l’uracile, sont également des composants essentiels de l’ADN et de l’ARN et sont utilisés en chimiothérapie et dans les traitements antiviraux.
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4-[1,5-Bis-(2-methylsulfamoylethyl)-1H-indol-3-yl]-1-methylpyridinium chloride
CAS :<p>Please enquire for more information about 4-[1,5-Bis-(2-methylsulfamoylethyl)-1H-indol-3-yl]-1-methylpyridinium chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C20H27N4O4S2•ClDegré de pureté :Min. 95%Masse moléculaire :487.04 g/molAllopurinol impurity A
CAS :<p>Allopurinol is an anticancer drug that is used to treat leukemia and other cancers. Allopurinol impurity A is a byproduct of the production of allopurinol, which has been shown to have anticancer properties. It has been shown to suppress the expression of suppressor genes and up-regulated genes in pancreatic cancer cells. This compound also induces apoptosis in orthotopic liver cells in a process involving activation of caspase 3 and suppression of Akt signaling.</p>Degré de pureté :Min. 95%2,4-Diamino-7-pteridinemethanol
CAS :<p>2,4-Diamino-7-pteridinemethanol (2,4-DPPM) is a drug product and an impurity found in the synthesis of 2,4-diamino-7-(2H)-pteridinone. 2,4-DPPM is a synthetic product that can be used as an analytical standard for the determination of aminopyrine in pharmaceuticals and other organic compounds. This compound has been used in pharmacological studies to investigate its effects on various enzymes associated with metabolism. It has also been used as an impurity standard for HPLC analysis of aminopyrine.</p>Formule :C7H8N6ODegré de pureté :Min. 95%Masse moléculaire :192.18 g/mol(S)-Tenofovir
CAS :<p>(S)-Tenofovir ((S)-PMPA) is the less active S-enantiomer of Tenofovir which is a nucleotide reverse transcriptase inhibitor.</p>Formule :C9H14N5O4PDegré de pureté :99.9%Couleur et forme :SolidMasse moléculaire :287.21Pemetrexed impurity C
CAS :<p>Pemetrexed is a drug product that belongs to the group of drugs called antifolate agents. It is used in the treatment of cancer and is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The impurity C is a natural metabolite that can be found in urine as well as in plasma. This impurity has not been identified as a major metabolite of pemetrexed.</p>Formule :C40H40N10O13Degré de pureté :Min. 95%Masse moléculaire :868.81 g/molAllopurinol impurity E
CAS :<p>This product is a synthetic impurity of Allopurinol. It is a cyclization reaction product of dimethylhydrazine and allopurinol in the presence of an organic solvent such as DMF.</p>Formule :C7H9N3O3Degré de pureté :Min. 95%Masse moléculaire :183.16 g/molZolmitriptan related compound D
CAS :<p>Zolmitriptan related compound D is a drug product that is an analytical impurity of the active ingredient, zolmitriptan. It is a synthetic compound and has been shown to be metabolized in vivo in humans. The chemical name for Zolmitriptan related compound D is 3-acetyl-5-(4-methoxyphenyl)-1H-indole-2,3-dione. This compound has been shown to have niche pharmacological properties that are not shared with other compounds in the same class, such as zolmitriptan.</p>Formule :C19H25N3O4Degré de pureté :Min. 95%Masse moléculaire :359.42 g/molAllopurinol Sodium
CAS :<p>Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.</p>Formule :C5H4N4NaODegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :159.13-(Formylamino)-1H-pyrazole-4-carboxamide
CAS :<p>This product is an organic compound that has a molecular formula of C6H7N3O2. It is a white solid with a melting point of 76.5 °C and an elution time of 7 minutes (range, 1-10 minutes). The detection method is based on the color change from yellow to blue in the presence of dimethylformamide (DMF). This product is used as a solvent for various chemical reactions and can be used in the synthesis of other products. 3-(Formylamino)-1H-pyrazole-4-carboxamide is used in analytical chemistry to determine substances such as pH, ionic strength, and concentration. In addition, this product can be used to quantify substances such as drugs or pharmaceuticals.</p>Formule :C5H6N4O2Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :154.13 g/molClopidogrel Impurity A
CAS :<p>Clopidogrel Impurity A is a medicine that is used for the prevention of heart attacks, strokes, and blood clots in people with an increased risk of these events. It is not intended to be used for immediate relief from sudden symptoms. Clopidogrel Impurity A is a substance that may be found in some preparations of clopidogrel. The presence of this substance can be detected by liquid chromatography-mass spectrometry (LC-MS/MS) methods. The structural analysis of this substance was determined using enantiomeric resolution and chromatographic methods. This impurity has been shown to have no effect on the bioavailability of the parent drug, clopidogrel, when given orally to Sprague-Dawley rats.</p>Formule :C15H15Cl2NO2SDegré de pureté :Min. 95%Masse moléculaire :344.26 g/molMercaptopurine impurity standard
CAS :<p>Mercaptopurine impurity standard is a drug product that is used as an analytical reference standard in the development of drugs. Mercaptopurine impurity standard is a natural metabolite of 6-mercaptopurine, which is used to treat leukemia and other forms of cancer. It has been shown to have an anti-inflammatory effect, but this has not been confirmed. Mercaptopurine impurity standard is a synthetic compound that is made synthetically for use as an impurity standard. It has also been shown to be metabolized by cytochrome P450 enzymes, glutathione reductase, or conjugation with glucuronic acid. Mercaptopurine impurity standard has been shown to be stable under acidic conditions and heat treatment at temperatures up to 200°C.</p>Degré de pureté :Min. 95%3,4-Dihydro naratriptan
CAS :<p>3,4-Dihydro naratriptan is a medicinal compound that is used as an anti-migraine drug. It is a hydrogenated form of the parent molecule naratriptan and has been shown to have a reaction time of about 30 minutes when catalyzed by palladium. The impurity, 3,4-dihydro naratriptan sulfonamide, has been found to be less potent than the target compound and can be eliminated from the synthesis by using catalytic hydrogenation. 3,4-Dihydro naratriptan sulfonamide can also be reduced by catalytic hydrogenation to yield 3,4-dihydro naratriptan.</p>Formule :C17H23N3O2SDegré de pureté :Min. 95%Masse moléculaire :333.45 g/mol1,3-Dihydro-6-methylfuro[3,4-c]pyridin-7-ol
CAS :<p>1,3-Dihydro-6-methylfuro[3,4-c]pyridin-7-ol is a compound that contains impurities such as fatty acids and uridine. It has been found to be an inhibitor of α-mangostin adduct formation with fatty acids. Additionally, it has been shown to inhibit the activity of GSK-3β, an enzyme involved in various cellular processes. This compound also exhibits inhibitory effects on monascus and safranal, two enzymes involved in the production of certain compounds. Furthermore, it has been found to inhibit calpain, an enzyme responsible for protein degradation. The compound can be used in various research applications involving electrode modification and polylysine immobilization. It may also have potential interactions with other drugs such as cefdinir.</p>Formule :C8H9NO2Degré de pureté :Min. 95%Masse moléculaire :151.16 g/mol5-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide - EP
CAS :<p>5-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide - EP is an impurity found in the synthetic process of iopamidol. It is a nonionic chemical that has been shown to be synthesized using the following methods: dichloride and synthetic. 5-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide - EP is used as a contrast agent for magnetic resonance imaging (MRI).</p>Formule :C14H18I3N3O6Degré de pureté :Min. 95%Masse moléculaire :705.02 g/molNeopterin
CAS :<p>D-(+)-Neopterin (D-(+)-Neopterin) is produced by human monocytes/macrophages upon stimulation with the cytokine interferon-γ.</p>Formule :C9H11N5O4Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :253.21Palonosetron
CAS :<p>Palonosetron, a 5-HT3 antagonist with Ki of 0.17 nM, is used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).</p>Formule :C19H24N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :296.41Ormetoprim
CAS :<p>Ormetoprim (Ro 5-9754), an antibiotic approved for use in the United States, is used to prevent the spread of disease in freshwater aquaculture.</p>Formule :C14H18N4O2Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :274.32Tenofovir diphosphate
CAS :<p>TFV-DP inhibits DNA polymerases, mimics dATP, and is used by HIV-1's reverse transcriptase.</p>Formule :C9H16N5O10P3Couleur et forme :SolidMasse moléculaire :447.17OXSI-2
CAS :<p>OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM.</p>Formule :C18H15N3O3SDegré de pureté :98%Couleur et forme :Dark Orange SolidMasse moléculaire :353.39Tenofovir exalidex
CAS :<p>Tenofovir exalidex (CMX 157) is a lipid-conjugated acyclic nucleotide analog of Tenofovir, demonstrating efficacy against wild-type and antiretroviral-resistant</p>Formule :C28H52N5O5PDegré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :569.72
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