Dérivés des Purines et Pyrimidines
Les purines possèdent une structure bicyclique, composée d’un cycle à six membres fusionné avec un cycle à cinq membres, tous deux contenant des atomes d’azote à des positions clés. Les dérivés des purines, tels que l’adénine et la guanine, sont essentiels à la formation de l’ADN et de l’ARN. Ces composés ont des applications thérapeutiques dans le traitement du cancer et des maladies virales en inhibant la réplication cellulaire. Les pyrimidines, quant à elles, possèdent une structure monocyclique à six membres avec deux atomes d’azote. Leurs dérivés, tels que la cytosine, la thymine et l’uracile, sont également des composants essentiels de l’ADN et de l’ARN et sont utilisés en chimiothérapie et dans les traitements antiviraux.
Chez CymitQuimica, nous proposons des dérivés des purines et pyrimidines pour la recherche en biologie moléculaire, génomique et le développement de thérapies innovantes.
8896 produits trouvés pour "Dérivés des Purines et Pyrimidines"
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[6-(3-Aminomethyl-piperidin-1-yl)-pyrimidin-4-yl]-cyclopropyl-amine hydrochloride
CAS :Degré de pureté :95.0%Masse moléculaire :283.799987792968754-[6-(2-Methoxy-phenyl)-pyridin-3-yl]-pyrimidin-2-ylamine
Degré de pureté :95.0%Masse moléculaire :278.315002441406253-TERT-BUTYL-1-CYCLOHEXYL-1-(6-HYDROXYHEXYL)UREA
Degré de pureté :95.0%Masse moléculaire :298.471008300781252-Chloro-4,6-diphenylpyrimidine
CAS :Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :266.73001098632816-ethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
CAS :Degré de pureté :98%Masse moléculaire :140.141998291015622-[5-amino-3-(2-thienyl)-1H-pyrazol-1-yl]-5-ethyl-6-methylpyrimidin-4(3H)-one
CAS :Degré de pureté :95.0%Masse moléculaire :301.36999511718752-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)pyrimidine
CAS :Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :298.346008300781251-(3-Methylbut-2-en-1-yl)guanidine hydrochloride(1:x)
CAS :Degré de pureté :97.0%Masse moléculaire :163.6499938964846-hydroxy-5-nitro-1,2,3,4-tetrahydropyrimidine-2,4-dione
Degré de pureté :98%Masse moléculaire :173.08399963378906Ref: 10-F788415
1gÀ demander2gÀ demander5gÀ demander10gÀ demander25gÀ demander100mgÀ demander250mgÀ demander500mgÀ demander4,6-Diphenylpyrimidin-2-amine
CAS :Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :247.300994873046884-(Chloromethyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide
CAS :Degré de pureté :95+%Masse moléculaire :429.9100036621094ETHYL 2-(2,6-DICHLORO-9H-PURIN-9-YL)ACETATE
CAS :Degré de pureté :90.0%Masse moléculaire :275.08999633789068-(2,2,2-trifluoroethyl)-7H-purin-6-amine
CAS :Degré de pureté :97%Masse moléculaire :217.154998779296882-(1-naphthyl)pyrimidine-5-carbaldehyde
CAS :Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :234.25799560546875N-(4-Fluorobenzyl)-2-((R)-5-(3-methylureido)-2',4'-dioxo-2,3-dihydrospiro[indene-1,5'-oxazolidin]-3'-yl)-N-((S)-1,1,1-trifluoropropan-2-yl)acetamide
CAS :Degré de pureté :97.0%Masse moléculaire :536.1682827485-{[(4,6-dimethylpyrimidin-2-yl)thio]methyl}-4-(4-fluorophenyl)-4H-1,2,4-triazole-3-thiol
CAS :Degré de pureté :95.0%Masse moléculaire :347.0674656686-[(4-Nitrobenzyl)thio]-9-β-D-ribofuranosylpurine
CAS :Degré de pureté :98.0%Masse moléculaire :419.41000366210942,3-Diamino-6-(trifluoromethyl)-4(3H)-pyrimidinone
CAS :Formule :C5H5F3N4ODegré de pureté :99.0%Couleur et forme :SolidMasse moléculaire :194.1174-[2'-(7''-Deazaguanine)ethyl]benzoic acid N-hydroxysuccinimide ester
CAS :<p>4-[2'-(7''-Deazaguanine)ethyl]benzoic acid N-hydroxysuccinimide ester is a useful intermediate in the synthesis of 7''-deazaguanine, which is a key building block in the synthesis of DNA. 4-[2'-(7''-Deazaguanine)ethyl]benzoic acid N-hydroxysuccinimide ester is a versatile building block that can be used in the synthesis of complex compounds. It has been shown to react with amines, sulfonyl chlorides, and epoxides to form amides, sulfonamides, and epoxy amines respectively. The CAS number for this compound is 204257-65-8.</p>Formule :C19H17N5O5Degré de pureté :Min. 95%Masse moléculaire :395.37 g/molMethotrexate dimethylamide
CAS :<p>Methotrexate dimethylamide is a research and development impurity standard with high purity. It is a synthetic drug product that can be custom synthesized to meet the needs of the customer. Methotrexate dimethylamide has been used as an analytical standard for HPLC analysis and as a natural metabolite in metabolism studies. This compound is also known as 71074-44-7, CAS No. 71074-44-7, or Metabolite.</p>Formule :C22H27N9O4Degré de pureté :Min. 95%Masse moléculaire :481.51 g/molTenofovir disoproxil related compound B
CAS :<p>Tenofovir disoproxil related compound B is a peptidyl prodrug that is metabolized by esterases to tenofovir. It has been shown to be an effective agent against Mycobacterium tuberculosis and other bacterial species. Tenofovir disoproxil related compound B was also found to inhibit protein synthesis in Mycobacterium avium and Mycobacterium smegmatis, but not in Escherichia coli. This drug binds to the ribosome's 30S subunit, which blocks the binding of aminoacyl-tRNA and prevents the formation of peptide bonds. The mechanism of action for this drug is similar to that of the antibiotic erythromycin.</p>Formule :C8H9N5Degré de pureté :Min. 98 Area-%Masse moléculaire :175.19 g/molN-Acetylmemantine
CAS :<p>N-Acetylmemantine is a drug that inhibits the activity of acetylcholinesterase in the brain. It has been shown to inhibit cancer cell growth and induce apoptosis, as well as inhibit the reaction of hydrolysis of acetonitrile with hydrochloric acid in an organic solvent. N-Acetylmemantine is synthesized by heating ethylene in the presence of hydrochloric acid. The synthesis yields a white solid that consists mainly of N-acetylmethamphetamine. This drug interacts with cellular membranes, which may be due to its ability to react with cholesterol or phospholipids. The interaction leads to changes in membrane permeability, which can result in apoptosis.</p>Formule :C14H23NODegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :221.34 g/molPemetrexed related impurity 2
<p>Pemetrexed related impurity 2 is a drug product that is an analytical impurity found in the metabolite of pemetrexed. It has been shown to be naturally occurring and is not toxic at high doses. This impurity has been synthesized as an impurity standard for HPLC. Pemetrexed related impurity 2 is used in research and development studies for drug development, such as pharmacopoeia testing for high purity standards.</p>Formule :C20H21N5O8Degré de pureté :Min. 95%Masse moléculaire :459.41 g/molMemantine impurity IV
CAS :<p>Memantine impurity IV is a hydrolysis product of memantine. It appears as a white to off-white powder and has a molecular weight of 198.1 g/mol. Memantine impurity IV is an intermediate in the production of memantine and is therefore not used for any other purpose. The compound contains hydroxy groups, hydroxy, alcohols, and bridgehead groups which are efficient at hydrolyzing to form amino acids.</p>Formule :C12H21NO·HClDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :231.76 g/mol3-Amino-4-carbamoylpyrazole hemisulfate
CAS :<p>3-Amino-4-carbamoylpyrazole hemisulfate is a white to yellowish crystalline powder that is soluble in water and methanol. It is a condensation product of allopurinol and ethyl orthoformate with a molecular weight of 312.4. 3-Amino-4-carbamoylpyrazole hemisulfate can be used as an anti-inflammatory agent, but it has not been approved for medical use in the United States.</p>Formule :C4H6N4OH2O4SDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :175.16 g/molTenofovir isoproxil monoester
CAS :<p>Tenofovir isoproxil monoester is a prodrug of Tenofovir, which is an antiviral drug. Tenofovir prevents the growth of HIV by interfering with the synthesis of viral DNA. The process development stage involves converting Tenofovir to its disoproxil monoester form, which has been shown to have greater antiviral activity than Tenofovir alone. This conversion process involves condensing one molecule of fumarate with two molecules of tenofovir, forming tenofovir disoproxil fumarate (TFD). TFD can be converted back to Tenofovir using hydrolysis and hydrogenation. Impurities in TFD include isopropyl tenofovir and unidentified impurities that are not present in the parent drug, tenofovir. Tenofovir Disoproxil Fumarate was also shown to be more potent than TFD and is undergoing clinical trials for</p>Formule :C14H22N5O7PDegré de pureté :Min. 97 Area-%Couleur et forme :White/Off-White SolidMasse moléculaire :403.33 g/mol4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoic acid
CAS :<p>4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoic acid is a drug with low bioavailability. It is used to treat leishmaniasis, an infection caused by the parasite Leishmania. 4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoic acid inhibits the synthesis of folic acid by blocking the enzyme dihydrofolate reductase in the bacteria. This drug also has been shown to be effective against autoimmune diseases and inflammatory bowel disease. The terminal half-life of 4-[(2,4-diamino6 pteridinyl)methyl]methylamino benzoic acid is approximately 5 hours and it can be detected in urine for up to 12 hours after administration.</p>Formule :C15H15N7O2Degré de pureté :(1H-Nmr) Min. 95 Area-%Couleur et forme :Brown Yellow PowderMasse moléculaire :325.33 g/molAllopurinol impurity C
CAS :<p>Allopurinol impurity C is a product of the reaction between allopurinol and n-butyl alcohol, which occurs in the presence of sodium hydroxide solution and dimethylformamide. The reaction condition is heated to reflux for 12 hours, after which the mixture is filtered and concentrated under reduced pressure. The resultant crude product is purified by column chromatography with ethyl acetate and then recrystallized from methanol. The synthesis scheme can be found in Figure 1.</p>Formule :C6H6N6ODegré de pureté :Min. 95%Couleur et forme :Slightly Yellow PowderMasse moléculaire :178.15 g/molEthyl 3-aminopyrazole-4-carboxylate
CAS :<p>Ethyl 3-aminopyrazole-4-carboxylate is an anticancer drug that inhibits the growth of cancer cells by inhibiting protein synthesis. It has been shown to inhibit the activity of dpp-iv and pde5, which are enzymes involved in cellular proliferation. Ethyl 3-aminopyrazole-4-carboxylate has also been shown to have antiinflammatory properties, which may be due to inhibition of prostaglandin synthesis. <br>Ethyl 3-aminopyrazole-4-carboxylate is a multinuclear compound that reacts with nitrogen atoms from the pyrazoles to form a stable molecule. Dimethylformamide is used as a solvent for this reaction. The synthesis of ethyl 3-aminopyrazole-4-carboxylate starts with acetylation, which converts the carboxylic acid group into an acetic acid group. The acetic acid group reacts with ammonia and hydrogen cyan</p>Formule :C6H9N3O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :155.16 g/molN-(5-Aminopentyl) methotrexate amide
CAS :<p>N-(5-Aminopentyl) methotrexate amide is a fluorescent probe that is used to study the transport of drugs across cell membranes. It binds to the plasma membrane of cells and can be visualized with a fluorescence microscope. N-(5-Aminopentyl) methotrexate amide has been shown to bind to leukemia cells in murine leukemia models. It has a high affinity for drug-resistant cells, which makes it useful for studying drug resistance mechanisms. This probe can be used at nanomolar concentrations for imaging studies, as well as for measuring the uptake of drugs into cancer cells by flow cytometry.</p>Formule :C25H34N10O4Degré de pureté :Min. 95%Couleur et forme :Yellow PowderMasse moléculaire :538.6 g/mol(2-(Dimethylamino)pyrimidin-5-yl)boronic acid
CAS :Formule :C6H10BN3O2Degré de pureté :97%Couleur et forme :SolidMasse moléculaire :166.982-PYRIMIDINECARBOXYLIC ACID, 5-METHOXY-
CAS :Formule :C6H6N2O3Degré de pureté :95%Couleur et forme :SolidMasse moléculaire :154.125(R)-4-Phenyl-2-(pyrimidin-2-yl)-4,5-dihydrooxazole
CAS :Degré de pureté :97%Masse moléculaire :225.25100715-Ethynyl-2′-deoxyuridine
CAS :Formule :C11H12N2O5Degré de pureté :95%Couleur et forme :SolidMasse moléculaire :252.226(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-((2,2,10,10-tetramethyl-4,8-dioxo-3,9-dioxa-5,7-diazaundecan-6-ylidene)amino)pentanoic acid
CAS :Degré de pureté :95%Couleur et forme :SolidMasse moléculaire :596.68103032-Chloro-N,N-dimethylpyrimidin-5-amine
CAS :Formule :C6H8ClN3Degré de pureté :97%Masse moléculaire :157.6Methyl 2-(methylthio)pyrimidine-4-carboxylate
CAS :Degré de pureté :98%Masse moléculaire :184.21000674-Chloro-2-(trifluoromethyl)pyrimidine
CAS :Formule :C5H2ClF3N2Degré de pureté :98%Couleur et forme :LiquidMasse moléculaire :182.532-Chloro-5-ethnylpyrimidine
CAS :Formule :C6H3ClN2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :138.555-Bromo-2-(cyclopropylmethoxy)pyrimidine
CAS :Formule :C8H9BrN2ODegré de pureté :98%Masse moléculaire :229.077
![[6-(3-Aminomethyl-piperidin-1-yl)-pyrimidin-4-yl]-cyclopropyl-amine hydrochloride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF089101.webp&w=3840&q=75)
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![6-[(4-Nitrobenzyl)thio]-9-β-D-ribofuranosylpurine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF547423.webp&w=3840&q=75)
![4-[2'-(7''-Deazaguanine)ethyl]benzoic acid N-hydroxysuccinimide ester](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FFD20837.webp&w=3840&q=75)
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