Dérivés de Quinazoline et de Quinoléine
Les quinazolines et les quinoléines sont des composés hétérocycliques azotés à structure aromatique qui jouent un rôle clé dans la synthèse de médicaments à activité anticancéreuse, antimicrobienne et anti-inflammatoire. Leurs dérivés présentent des modifications structurelles qui optimisent leur biodisponibilité et leur sélectivité, permettant ainsi le développement de nouveaux principes actifs pour diverses applications thérapeutiques. Ces composés sont utilisés dans la fabrication d’API destinés au traitement du cancer, des infections, des maladies neurodégénératives et cardiovasculaires. De plus, les dérivés de quinazoline et de quinoléine sont essentiels dans la recherche d’inhibiteurs enzymatiques et dans la conception de molécules bioactives innovantes.
Chez CymitQuimica, nous proposons des dérivés de quinazoline et de quinoléine de haute pureté pour des applications en synthèse chimique, développement pharmaceutique et biotechnologie.
65644 produits trouvés pour "Dérivés de Quinazoline et de Quinoléine"
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N-methoxy-N-methyl-2-phenylquinoline-4-carboxamide
CAS :Degré de pureté :95.0%Masse moléculaire :292.33801269531252-HYDROXY-6-((2-(1-ISOPROPYL-1H-PYRAZOL-5-YL)PYRIDIN-3-YL)METHOXY)BENZALDEHYDE
CAS :Degré de pureté :95.0%Masse moléculaire :337.3789978027344Cilostazol
CAS :Produit contrôlé<p>Applications A potent phosphodiesterase III A (PDE3A) inhibitor (IC50=0.2uM) and inhibitor of adenosine uptake. Has antimitogenic, antithrombotic, vasodilatory and cardiotonic properties in vivo. Also affects lipid levels in vivo. Neuroprotective & Neuroresearch product.<br>References Suri, A., et al.: J. Clin. Pharmacol., 38, 144 (1998), Park, S.-W., et al.: Am. J. Cardiol., 84, 511 (1999), Tsuchikane, E., et al.: Circulation, 100, 21 (1999),<br></p>Formule :C20H27N5O2Couleur et forme :NeatMasse moléculaire :369.46N-(3-Chloro-4-(((2-(methylamino)-6-(pyridin-2-yl)pyrimidin-4-yl)amino)methyl)phenyl)methanesulfonamide
CAS :Degré de pureté :98.0%Masse moléculaire :418.8999938964844Hydroxythiovardenafil
CAS :Produit contrôlé<p>Applications Hydroxythiovardenafil is a hydroxylated thiol analogue of the PDE 5 inhibitor Vardenafil (H995300).<br></p>Formule :C23H32N6O4S2Couleur et forme :Light Yellow SolidMasse moléculaire :520.672-[(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]-n-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1h-pyrazol-4-yl)propanamide
CAS :Degré de pureté :97%Masse moléculaire :390.48001098632811-(3-Chlorophenyl)-3-thiophen-2-yl-1H-pyrazole-5-carboxylic acid
CAS :Degré de pureté := 98% (HPLC)Masse moléculaire :304.75Stiripentol
CAS :Produit contrôlé<p>Applications An epilepsy drug. It has been used as co-therapy for treatment of epilepsy. It inhibits the enzymes responsible for metabolism of other anti-convulsant agents.<br>References Laurie, D., et al.: J. Neurosci., 12, 4151 (1992), Smith, A., et al.: J. Pharmacol. Exp. Therap., 311, 601 (2004), Trojnar, M., et al.: Pharm. Rep., 57, 154 (2005), Drafts, B., et al.: J. Pharm. Exp. Ther., 318, 1094 (2006), Picton, A., et al.: Brain Res., 1165, 40 (2007),<br></p>Formule :C14H18O3Couleur et forme :Light Yellow SolidMasse moléculaire :234.292-([1,1'-Biphenyl]-4-yl)-6-fluoroquinoline-4-carboxylic acid
CAS :Degré de pureté :98%Masse moléculaire :343.35699462890625Ethyl 6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
CAS :Produit contrôlé<p>Applications Ethyl 6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate is an impurity of Apixaban (A726700), A potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.<br>References Nevuluri, N. et al.: Monat. fuer Chem., 148, 1477 (2017);<br></p>Formule :C22H22N4O4Couleur et forme :NeatMasse moléculaire :406.43Oxaprozin-d10
CAS :Produit contrôlé<p>Applications Oxaprozin-d10 is the labeled analogue of Oxaprozin (O845400), an anti-inflammatory drug. Oxaprozin was comparable to Aspirin (A687780).<br>References Whitehouse, M.W., et al.: Biochem. Pharmacol., 20, 2309 (1971); Janssen, F.W., et al.: Drug Metab. Dispos., 6, 465 (1978); Shriver, D.A., et al.: Toxicol. Appl. Pharmacol., 42, 75 (1977)<br></p>Formule :C18H5D10NO3Couleur et forme :NeatMasse moléculaire :303.382-[5-bromo-2-(pyridin-2-yl)-1H-indol-3-yl]ethan-1-amine hydrochloride
CAS :Degré de pureté :95.0%Masse moléculaire :352.66000366210942-(Chloromethyl)-4-methylquinazoline
CAS :Produit contrôlé<p>Impurity Linagliptin 2-Chloromethyl Impurity<br>Applications 2-(Chloromethyl)-4-methylquinazoline, is a building block used for the preparation of Linagliptin (L465900), and its impurities, acting as type 2 diabetes drugs.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011); Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011);<br></p>Formule :C10H9ClN2Couleur et forme :NeatMasse moléculaire :192.646-Bromo-7-methoxy-2-methylquinazolin-4(3H)-one
CAS :Degré de pureté :97.0%Masse moléculaire :269.0979919433594Saxagliptin Hydrochloride
CAS :Produit contrôlé<p>Applications Saxagliptin is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.<br>References Feng, J., et al.: J. Med. Chem., 50, 2297 (2007), Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008), Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008),<br></p>Formule :C18H25N3O2·ClHCouleur et forme :NeatMasse moléculaire :351.87N-Demethylivabradine
CAS :Produit contrôléFormule :C26H34N2O5Couleur et forme :Light Brown To BrownMasse moléculaire :454.56[4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]phenyl]cyclopropylmethanone
CAS :Produit contrôlé<p>Applications [4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]phenyl]cyclopropylmethanone is an impurity of Haloperidol (H103700), an antidyskinetic; antipsychotic.<br>References Janicki, C.A., et al.: Anal. Profiles Drug Subs., 9, 341 (1980); Beresford, R., et al.: Drugs, 33, 31 (1987)<br></p>Formule :C21H22ClNO2Couleur et forme :NeatMasse moléculaire :355.86Diethyl 2-Acetamido-2-[2-(4-octylphenylethyl)malonate
CAS :Produit contrôlé<p>Applications An impurity found in fingolimod (F805000).<br></p>Formule :C25H39NO5Couleur et forme :NeatMasse moléculaire :433.585-(Pyridin-2-yl)thiophene-2-carbaldehyde
CAS :Formule :C10H7NOSDegré de pureté :97.0%Couleur et forme :SolidMasse moléculaire :189.23N-Chloro Ethyl ThioTEPA
CAS :Produit contrôlé<p>Stability Hygroscopic, Moisture Sensitive<br>Applications N-Chloro Ethyl ThioTEPA is an impurity of ThioTEPA which is an alkylating agent used to treat cancer.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Maanen, M., et al.: Cancer Treatment Rev., 26, 257 (2000); Sykes, M., et al.: Cancer, 6, 142 (1953)<br></p>Formule :C6H13ClN3PSCouleur et forme :White To Off-WhiteMasse moléculaire :225.68Nimodipine
CAS :<p>Applications A dihydropyridine calcium channel blocker. It is used as a vasodilator (cerebral). Neuroprotective & Neuroresearch products.<br>References Allen, G.S., et al.: N. Engl. J. Med., 308, 619 (1983), Schluter, H.: Arzneim.-Forsch., 36, 1733 (1986), Deyo, R.A., et al.: Science, 243, 809 (1989),<br></p>Formule :C21H26N2O7Couleur et forme :NeatMasse moléculaire :418.44Vismodegib
CAS :Produit contrôlé<p>Applications Vismodegib targets the Hedgehog (Hh) pathway. Inhibition of the Hh signaling may be effective in the treatment and prevention of many types of human cancers. Potent Hedgehog inhibitor.<br>References Gupta, S. et al.: Ther. Advances in Med. Oncology 2,237(2010)<br></p>Formule :C19H14Cl2N2O3SCouleur et forme :Off-WhiteMasse moléculaire :421.30Vortioxetine
CAS :Produit contrôlé<p>Applications Vortioxetine can be used in biological study of effectiveness of long term vortioxetine treatment of patients with major depressive disorder.<br>References Vieta, E., et al.: Eur Neuropsychopharm (2017)<br></p>Formule :C18H22N2SCouleur et forme :NeatMasse moléculaire :298.45Alogliptin-d3
CAS :Produit contrôlé<p>Applications Labelled Alogliptin (A575425). It is an oral antihyperglycemic agent that is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4). Antidiabetic agent.<br>References Lynn, F., et al.: Diabetes, 50, 1004 (2001), Trumper, A., et al.: J. Endocrinol., 174, 233 (2002), Vollmer, K., et al.: J. Clin. Endocrinol. Metab., 94, 1379 (2009),<br></p>Formule :C182H3H18N5O2Couleur et forme :NeatMasse moléculaire :342.41Trametinib
CAS :Produit contrôlé<p>Applications Used in the systematic treatment of advanced cutaneous melanoma. An EGFR kinase inhibitor and potent MEK inhibitor.<br>References Ercan, D. et al.: Canc. Disc., 2, 934 (2012); Mackiewicz-Wysocka, M. et al.: Exp. Opin. Investig. Drugs., 22, 181 (2013);<br></p>Formule :C26H23FIN5O4Couleur et forme :Off-WhiteMasse moléculaire :615.392-(PYRIDIN-3-YLMETHYL)QUINUCLIDIN-3-ONE
CAS :Degré de pureté :95.0%Masse moléculaire :216.28399658203125Irbesartan-d4
CAS :Produit contrôlé<p>Applications Irbesartan-d4 is the labeled analogue of Irbesartan (I751000), an angiotensin II type 1 (AII1)-receptor antagonist.<br>References Gillis, J.C. and Markham, A.: Drugs, 54, 885 (1997); Chando, T.J., et al.: Drug. Metabol. Dispos., 26, 408 (1998); Massie, B., et al.: New Eng. J. Med., 359, 2456 (2008); Ren, X., et al.: Pharmacol., 83, 80 (2009)Aromatics, Heterocycles, Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals<br></p>Formule :C25H24D4N6OCouleur et forme :NeatMasse moléculaire :432.55Felbamate-d4
CAS :Produit contrôlé<p>Applications Antiepileptic, structurally similar to meprobamate.<br>References Swinyard, E.A., et al.: Epilepsia, 27, 27 (1986), Remmel, R.P., et al.: Ther. Drug Monit., 12, 90 (1990), Sofia, R.D., et al.: Epilepsy Res. Suppl., 3, 103 (1991),<br></p>Formule :C11H10D4N2O4Couleur et forme :NeatMasse moléculaire :242.267Vildagliptin Amide
CAS :Produit contrôlé<p>Impurity Vildagliptin Amide Impurity<br>Applications N-(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)glycyl-L-prolinamide is an impurity of Vildagliptin (V305000) which is an oral anti-hyperglycemic agent that inhibit dipeptidyl peptidase 4 (DPP-4).<br>References Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al.: Diabetes Care, 27, 2874 (2004), Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004),<br></p>Formule :C17H27N3O3Couleur et forme :Off-WhiteMasse moléculaire :321.41Nifursol (~90%)
CAS :Produit contrôlé<p>Applications A medicinal, prophylactic additive in animal feeds, protecting poultry from histomoniasis.Environmental contaminants; Food contaminants; Heat processing contaminants<br>References Kowalski, P., et al.: J. Pharm. Biomed. Anal., 32, 937 (2003), Khlebnikov, A., et al.: Bioorg. Med. Chem., 16, 9302 (2008), Schepetkin, I., et al.: Mol. Pharmacol., 74, 392 (2008),<br></p>Formule :C12H7N5O9Degré de pureté :~90%Couleur et forme :NeatMasse moléculaire :365.212-amino-N-phenylquinoline-3-carboxamide
CAS :Degré de pureté :97%Masse moléculaire :263.29998779296875Methyl 4’-[[2-n-Propyl-4-methyl-6-(1-methylbenzimidazol-2-yl)-benzimidazol-1-yl]methyl]biphenyl-2-ca
CAS :Formule :C34H32N4O2Couleur et forme :YellowMasse moléculaire :528.64Maraviroc
CAS :Produit contrôléFormule :C29H41F2N5OCouleur et forme :White To Off-WhiteMasse moléculaire :513.674-Anilino-4-oxobutanoic Acid
CAS :Produit contrôlé<p>Applications The metabolite (MII) of Suberoylanilide Hydroxamic Acid (S688700).<br>References Sun, W.S., et al.: J. Med. Chem., 46, 5619 (2003)<br></p>Formule :C10H11NO3Couleur et forme :NeatMasse moléculaire :193.20Dehydro Nimodipine
CAS :Produit contrôlé<p>Impurity Nimodipine EP Impurity A; Nimodipine USP Related Compound A<br>Stability Light Sensitive<br>Applications Dehydro Nimodipine (Nimodipine EP Impurity A; Nimodipine USP Related Compound A) is the dehydrogenated analogue and the major metabolite of the calcium channel blocker Nimodipine (N478200).<br>References Scherling, D. et al.: Arzneim.-Forsch., 41, 392 (1991); Liu, X. et al.: Yaox. Xueb., 35, 257 (2000); Eicher, H. et al.: Arch. Gerontol. Geriat., 14, 309 (1992);<br></p>Formule :C21H24N2O7Couleur et forme :Light YellowMasse moléculaire :416.42Levetiracetam-d3
CAS :Produit contrôléFormule :C8H11D3N2O2Couleur et forme :White To Off-WhiteMasse moléculaire :173.234-Fluoro-3-(((5-(1-methyl-1H-pyrazol-3-yl)pyridin-3-yl)methyl)amino)-N-(3-(trifluoromethoxy)phenyl)benzamide
CAS :Degré de pureté :97.0%Masse moléculaire :485.4429931640625Levetiracetam
CAS :<p>Applications The (S)-enantiomer of Etiracetam (E932970) and the ethyl analog of Piracetam (P500800). Used as an anticonvulsant. Neuroprotective & Neuroresearch Product.<br>References Gower, A.J., et al.: Eur. J. Pharmacol., 222, 193 (1992); Kasteleijn-Noist Trenite, D.G.A., et al.: Epilepsy Res., 25, 225 (1996); Patsalos, P.N., et al.: Pharmacol. Ther., 85, 77 (2000)<br></p>Formule :C8H14N2O2Couleur et forme :NeatMasse moléculaire :170.213-Bromo-5-(3-phenyl-[1,2,4]oxadiazol-5-yl)-pyridine
Degré de pureté :95.0%Masse moléculaire :302.13101196289062-Amino-3-iodopyrazine
CAS :Formule :C4H4IN3Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :221.0014-(Indolin-5-yl)morpholine hydrochloride
CAS :Degré de pureté :95.0%Masse moléculaire :240.729995727539065-(4-Chloro-phenyl)-2-phenyl-2H-pyrazol-3-ylamine
CAS :Degré de pureté :95.0%Masse moléculaire :269.7300109863281Benzyl (5-bromopyridin-3-yl)carbamate
CAS :Degré de pureté :95.0%Masse moléculaire :307.14700317382818-methyl-4-(pyridine-4-carbonyl)-1-oxa-4-azaspiro[4.5]decane-3-carboxylic acid
CAS :Degré de pureté :95.0%Masse moléculaire :304.34600830078125(2S,3S,5S)-5-Amino-1,6-diphenyl-2-([[thiazol-5-ylmethoxy)carbonyl]amino]hexan-3-yl 2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido)-3-methylbutanoate Hydrochloride
CAS :Produit contrôlé<p>Applications (2S,3S,5S)-5-amino-1,6-diphenyl-2-([[thiazol-5-ylmethoxy)carbonyl]amino]hexan-3-yl 2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido)-3-methylbutanoate Hydrochloride, is a prodrug of Ritonavir (R535000), which is a selective HIV protease inhibitor.<br>References Daluge, S., et al.: Antimicrob. Agents Chemother., 38, 1590 (1994), Ammaranond, P., et al.: J. Clin. Virol., 26, 153 (2003), Harrigan, P., et al.: J. Infect. Dis., 191, 339 (2005), Miller, J., et al.: Bioorg. Med. Chem. Lett., 16, 1788 (2006);<br></p>Formule :C37H48N6O5S2•xHClCouleur et forme :NeatMasse moléculaire :720.944,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-Pyrazolo[3,4-c]pyridine-3-carboxylic Acid Methyl Ester
CAS :Produit contrôléFormule :C26H26N4O5Couleur et forme :NeatMasse moléculaire :474.5085-Hydroxy Omeprazole-d3 Sodium Salt
CAS :Produit contrôléFormule :C17H15D3N3NaO4SCouleur et forme :White To Light YellowMasse moléculaire :386.421-Isopropenyl-2-benzimidazolidinone
CAS :Produit contrôlé<p>Applications 1-Isopropenyl-2-benzimidazolidinone (cas# 52099-72-6) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formule :C10H10N2OCouleur et forme :NeatMasse moléculaire :174.204-(6-o-Tolyl-pyridin-3-yl)-pyrimidin-2-ylamine
Degré de pureté :95.0%Masse moléculaire :262.31600952148444-(4-ETHYNYLPHENYL)MORPHOLINE
CAS :Degré de pureté :95.0%Couleur et forme :Liquid, No data available.Masse moléculaire :187.242004394531259-Piperazino Levofloxacin Impurity
CAS :Produit contrôlé<p>Applications A degradation product of Levofloxacin (L360000). Levofloxacin impurity.<br>References ierens, C., et al.: J. Pharm. Biomed. Anal., 22, 763 (2000), Kitade, T., et al.: Chem. Pharm. Bull., 51, 53 (2003), Liang, Y., et al.: Anal. Chim. Acta, 510, 21 (2004),<br></p>Formule :C18H20FN3O4Couleur et forme :NeatMasse moléculaire :361.368(R)-Rivastigmine
CAS :Produit contrôlé<p>Impurity Rivastigmine EP Impurity D<br>Applications (R)-Rivastigmine (Rivastigmine EP Impurity D) is a carbamate inhibitor of acetylcholinesterase used as a treatment of Alzheimer’s disease.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lucangioli, S. E., et al.: J. Chromatogr. A, 1081, 31-35 (2005); Bar-On, P., et al.: Biochem., 41, 3555-3564 (2002);<br></p>Formule :C14H22N2O2·C4H6O6Couleur et forme :NeatMasse moléculaire :400.421,2,3,6-Tetrahydro-1-nitrosopyridine
CAS :Formule :C5H8N2OCouleur et forme :NeatMasse moléculaire :112.132-Nitrobenzaldehyde
CAS :<p>Applications 2-Nitrobenzaldehyde is a benzaldhyde with a nitro group substituted in the ortho position. 2-Nitrobenzaldehyde is used in the preparation of dyes and colorants such as Indigo carmine. 2-Nitrobenzaldehyde gas been shown to be a useful photoremovable protecting group as well as in the preparation of more effective ones such as o-Nitrophenylethylene glycol.<br>References Gravel, D. et al.: Can. J. Chem., 61, 400 (1983); Sebej, P. et al.: J. Org. Chem., 74, 8647 (2009); Das, A. et al.: J. Ind. Che,. Soc., 49, 993 (1972);<br></p>Formule :C7H5NO3Couleur et forme :NeatMasse moléculaire :151.122-(Aminomethyl)-1-ethylpyrrolidine
CAS :Produit contrôléFormule :C7H16N2Couleur et forme :Colourless To Light YellowMasse moléculaire :128.22Minoxidil Sulfate-d10
CAS :Produit contrôlé<p>Stability Light Sensitive - Protect from Light, Store in Freezer<br>Applications Labelled Minoxidil sulfate (M345100). Minoxidil sulfate is the active metabolite of Minoxidil and is a potent (IC50=0.14µM) vascular smooth muscle relaxant. Minoxidil sulfate is a selective ATP-sensitive potassium channel opener.<br>References Nakaya, Y., et al.: J. Dermatol. Sci., 7 (Suppl.), S104-S108 (1994), Ohtsuyama, M., et al.: J. Pharmacol. Exp. Ther., 269(2), 823 (1994), Andersson, K.E., et al.: Pharmacol. Toxicol., 70, 244 (1992), Bray, K.M., et al.: J. Biol. Chem., 267, 11689 (1992), Saitoh, M. et al.: Biochem. Biophys. Res. Commun., 140, 280 (1986)<br></p>Formule :C9H5D10N5O4SCouleur et forme :NeatMasse moléculaire :299.37Risperidone E-Oxime
CAS :Produit contrôléFormule :C23H28F2N4O2Couleur et forme :NeatMasse moléculaire :430.491-Methoxy-Empagliflozin Tetraacetoxy
CAS :Formule :C32H37ClO12Couleur et forme :NeatMasse moléculaire :649.0826-Chloro-3-iodo-2-(trifluoromethyl)pyridine
CAS :Degré de pureté :98+%Masse moléculaire :307.44000244140625Lansoprazole Sulfone-d4
CAS :Produit contrôléFormule :C16H10D4F3N3O3SCouleur et forme :NeatMasse moléculaire :389.381,2:4,5-bis-O-(1-Methylethylidene)-β-D-Fructopyranose
CAS :Produit contrôlé<p>Applications 1,2:4,5-bis-O-(1-Methylethylidene)-β-D-Fructopyranose is a reagent in the synthesis of antibacterial/antifungal monosaccaride esters. Also used in the synthesis of antihyperlipidemic novel compounds involving glycosyl fructose derivatives.<br>References Shen, Y. et al.: Molecules, 17, 8661 (2012); Tiwari, P. et al.: Bioorg. Med. Chem. Lett., 16, 6028 (2006);<br></p>Formule :C12H20O6Couleur et forme :NeatMasse moléculaire :260.284-Amino-2,6-dichloro-α-(4-chlorophenyl)benzeneacetonitrile
CAS :Produit contrôlé<p>Applications This compound is used in the synthesis of Diclazuril (D436200) and diclazuril derivatives.<br></p>Formule :C14H9Cl3N2Couleur et forme :NeatMasse moléculaire :311.59N-Benzyl Hydroxymedetomidine
CAS :Produit contrôlé<p>Applications N-Benzyl Hydroxymedetomidine is an impurity of Medetomidine (M203250, HCl); an α2-adrenergic agonist, sedative, and analgesic.<br>References Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987); Stenberg, D., et al.: J. Vet. Pharmacol. Ther., 10, 319 (1987); Virtanen, R., et al.: Eur. J. Pharmacol., 150, 9 (1988); Cullen, L.K., et al.: Br. Vet. J., 152, 519 (1996)<br></p>Formule :C20H22N2OCouleur et forme :NeatMasse moléculaire :306.4(S)-(-)-Thalidomide
CAS :Produit contrôlé<p>Applications Optically active isomer of Thalidomide, which inhibits FGF-induced angiogenesis. Inhibits replication of human immunodeficiency virus type 1. Teratogenic sedative.<br>References D’Amato, r.J., et al.: Proc. Natl. Acad. Sci. USA, 91, 4082 (1994), Makonkawkeyoon, S., et al.: Proc. Natl. Acad. Sci. USA, 90, 5974 (1993), Schumacher, H., et al.: J. Pharmacol. Exp. Therap., 160, 189 (1968)<br></p>Formule :C13H10N2O4Couleur et forme :White To Off-WhiteMasse moléculaire :258.23Ebastine-d5
CAS :Produit contrôlé<p>Applications A nonsedating type histamine H1-receptor antagonist. Antihistaminic.<br>References Vincent, J., et al.: Brit. J. Clin. Pharmacol., 26, 497 (1988)<br></p>Formule :C32H34D5NO2Couleur et forme :NeatMasse moléculaire :474.69N,N'-Methylene Ambroxol Hydrochloride
CAS :Produit contrôlé<p>Impurity Ambroxol EP Impurity B Hydrochloride<br>Stability Hygroscopic<br>Applications Ambroxol Cyclic Impurity is a metabolite as well as an impurity of the bronchosecretolytic drug, Ambroxol (A575900).<br>References Hammer, R. et al.: Arzneim.-Forsch., 28, 899 (1978); Nieder, M. et al.: HRC & CC, 9, 561 (1986); Huq, F. et al.: J. Pharmacol. Toxicol., 3, 147 (2008);<br></p>Formule :C14H18Br2N2O·ClHCouleur et forme :White To Off-WhiteMasse moléculaire :426.57N-Nitroso Desmethyl Olopatadine
Produit contrôléFormule :C20H20N2O4Couleur et forme :NeatMasse moléculaire :352.3844-[4-[(5S)-5-(Aminomethyl)-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone Hydrochloride
CAS :Produit contrôléFormule :C14H17N3O4·ClHCouleur et forme :NeatMasse moléculaire :327.76Carboxymefloquine-d3
CAS :Produit contrôlé<p>Applications Labelled Carboxymefloquine (C178700). Carboxymefloquine is a metabolite of Mefloquine (M207050).<br>References Crevoisier, C., et al.: Eur. J. Clin. Pharmacol., 53, 135 (1997), Ridtitid, W., et al.: J. Pharm. Pharmacol., 52, 1265 (2000),<br></p>Formule :C12H2D3F6NO2Couleur et forme :NeatMasse moléculaire :312.181-Phenyl-3-thiophen-2-yl-1H-pyrazole-5-carboxylic acid
CAS :Couleur et forme :SolidMasse moléculaire :270.30999755859375(Z,Z)-5-(2-Methyl-3-phenyl-propenylidene)-4-oxo-2-thioxo-3-thiazolidineacetic Acid
CAS :Produit contrôlé<p>Stability Light Sensitive<br>Applications (Z,Z)-5-(2-Methyl-3-phenyl-propenylidene)-4-oxo-2-thioxo-3-thiazolidineacetic Acid is a stereoisomer of Epalrestat (E565300), an aldose reductase inhibitor. Used in the treatment of diabetic neuropathy.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Terashima, H., et al.: J. Pharmacol. Exp. Ther., 229, 226 (1983), Kikkawa, R., et al.: Diabetologia, 24, 290 (1983), Kojima, K., et al.: Jpn. J. Ophthalmol., 29, 99 (1985), Qi, M. et al.: J. Beij, Inst. Tech., 13, 445 (2004);<br></p>Formule :C15H13NO3S2Couleur et forme :Yellow-Red SolidMasse moléculaire :319.41,2,3,9-Tetrahydro-9-methyl-3-methylene-4H-carbazol-4-one
CAS :Produit contrôlé<p>Impurity Ondansetron EP Impurity D; Ondansetron USP Related Compound D<br>Applications 1,2,3,9-Tetrahydro-9-methyl-3-methylene-4H-carbazol-4-one (Ondansetron EP Impurity D; Ondansetron USP Related Compound D) is an impurity of Ondansetron (O655000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Feng, R. et al.: Zhong. Yaox. Zaz., 46, 1436 (2011); Zizkovsky, V. et al.: J. Pharm. Biomed. Anal., 44, 1048 (2007)<br></p>Formule :C14H13NOCouleur et forme :WhiteMasse moléculaire :211.261-(3-Hydroxypropyl)theobromine
CAS :Produit contrôléFormule :C10H14N4O3Couleur et forme :White To Off-WhiteMasse moléculaire :238.243Nimodipine-d7
CAS :Produit contrôlé<p>Applications A labelled dihydropyridine calcium channel blocker. It is used as a vasodilator (cerebral).<br>References Allen, G.S., et al.: N. Engl. J. Med., 308, 619 (1983), Schluter, H.: Arzneim.-Forsch., 36, 1733 (1986), Deyo, R.A., et al.: Science, 243, 809 (1989),<br></p>Formule :C21H19D7N2O7Couleur et forme :NeatMasse moléculaire :425.48Desfluoro Risperidone
CAS :Produit contrôlé<p>Impurity Risperidone EP Impurity K<br>Applications Desfluoro Risperidone (Risperidone EP Impurity K) is a Risperidone (R525000) impurity, as antipsychotics.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formule :C23H28N4O2Couleur et forme :NeatMasse moléculaire :392.49Deacetyl Ketoconazole
CAS :Produit contrôlé<p>Impurity Ketoconazole EP Impurity D<br>Applications Deacetyl Ketoconazole (Ketoconazole EP Impurity D) is a Ketoconazole derivative.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formule :C24H26Cl2N4O3Couleur et forme :Off-WhiteMasse moléculaire :489.391-Methoxy Empagliflozin
CAS :Produit contrôlé<p>Applications 1-Methoxy Empagliflozin is an impurity in the synthesis of Empagliflozin drug (E521510), which is potent and selective inhibitor of sodium glucose co-transporter-2 (SGLT-2).<br>References Thomas, L., et al.: Diabetes. Obesity. Metabol. 14, 94 (2012); Grempler, R., et al.: Diabetes. Obesity. Metabol., 14, 83 (2012);<br></p>Formule :C24H29ClO8Couleur et forme :White To Off-WhiteMasse moléculaire :480.942,5-Diamino-3-fluoro-4-(trifluoromethyl)pyridine
CAS :Formule :C6H5F4N3Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :195.121rac Metanephrine Hydrochloride Salt
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications A metabolite of Epinephrine (E588585). A naturraly occurring derivative of Epinephrine, found in urine and in certain tissues.<br>References Eisenhofer, G., et al.: J. Clin. Endocrinol. Metab., 82, 3864 (1997), Akiyama, T., et al.: Cardiovasc. Res., 49, 78 (2001), Burke, W., et al.: Brain Res., 891, 218 (2001),<br></p>Formule :C10H15NO3·ClHCouleur et forme :White To GreyMasse moléculaire :233.692-[1-Methyl-5-(trifluoromethyl)pyrazol-3-yl]-thiophene-5-carboxaldehyde
CAS :Formule :C10H7F3N2OSCouleur et forme :SolidMasse moléculaire :260.23Hydroxydehydro Nifedipine Carboxylate
CAS :Produit contrôléFormule :C16H14N2O7Couleur et forme :NeatMasse moléculaire :346.29(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane Hydrochloride
CAS :Produit contrôléFormule :C12H17NO2·ClHCouleur et forme :NeatMasse moléculaire :243.736-Chloro-pyrimidine-2,4-diamine
CAS :Produit contrôlé<p>Impurity Minoxidil EP Impurity B<br>Applications 6-Chloro-pyrimidine-2,4-diamine (cas# 156-83-2) is a compound useful in organic synthesis.<br></p>Formule :C4H5ClN4Couleur et forme :WhiteMasse moléculaire :144.56Azobenzene
CAS :<p>Applications Impurity in the production of Phenylbutazone (P319570). Dyes and metabolites.<br>References Chung, K., et al.: Mutation Res., 114, 269 (1983), Kawanishi, S., et al.: J. Biol. Chem., 261, 5952 (1986), Floyd, R., et al.: Carcinogenesis, 11, 1447 (1990), Shibutani, S., et al.: Nature, 349, 431 (1991),<br></p>Formule :C12H10N2Couleur et forme :NeatMasse moléculaire :182.22Saxagliptin Hydrate
CAS :Produit contrôlé<p>Applications Saxagliptin Hydrate is a selective and reversible dipeptidyl peptidase-4 (DPP4) inhibitor that may be used to develop treatment for type 2 diabetes.<br>References Gu, S., et al.: PLoS One. 11, e0167190 (2016); Dave, D. J.: J Pharmacol Pharmacother 2, 230 (2011)<br></p>Formule :C18H25N3O2·H2OCouleur et forme :NeatMasse moléculaire :333.437-Despropyl 7-Methyl Vardenafil
Produit contrôlé<p>Applications 7-Despropyl 7-Methyl Vardenafil is an impurity of Vardenafil (V098001, 2HCl); a selective phosphodiesterase type 5 (PDE5) inhibitor.<br>References Bischoff, E., et al.: J. Urol., 165, 1316 (2001); Kim, N.N., et al.: Life Sci., 69, 2249 (2001); Kendirci, M., et al.: Expert Opin. Pharmacother., 5, 923 (2004)<br></p>Formule :C21H28N6O4SCouleur et forme :Off White SolidMasse moléculaire :460.55
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