Dérivés de Quinazoline et de Quinoléine
Les quinazolines et les quinoléines sont des composés hétérocycliques azotés à structure aromatique qui jouent un rôle clé dans la synthèse de médicaments à activité anticancéreuse, antimicrobienne et anti-inflammatoire. Leurs dérivés présentent des modifications structurelles qui optimisent leur biodisponibilité et leur sélectivité, permettant ainsi le développement de nouveaux principes actifs pour diverses applications thérapeutiques. Ces composés sont utilisés dans la fabrication d’API destinés au traitement du cancer, des infections, des maladies neurodégénératives et cardiovasculaires. De plus, les dérivés de quinazoline et de quinoléine sont essentiels dans la recherche d’inhibiteurs enzymatiques et dans la conception de molécules bioactives innovantes.
Chez CymitQuimica, nous proposons des dérivés de quinazoline et de quinoléine de haute pureté pour des applications en synthèse chimique, développement pharmaceutique et biotechnologie.
65630 produits trouvés pour "Dérivés de Quinazoline et de Quinoléine"
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Linagliptin Methyl Dimer
CAS :Produit contrôlé<p>Applications Linagliptin Methyldimer is an impurity of Linagliptin (L465900). Linagliptin is a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.<br>References Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011); Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011)<br></p>Formule :C51H56N16O4Couleur et forme :NeatMasse moléculaire :957.095Roxatidine Acetate Hydrochloride
CAS :Produit contrôlé<p>Applications A histamine H2-receptor antagonist. It is used to inhibit gastric acid secretion; an antiulcer agent.<br>References Tarutani, M. et al.: Arzneim.-Forsch., 35, 703 (1985); Yagita, M. et al.: Therap. Res., 7, 96 (1987); Asai, M. et al.: Gek. Yak., 50, 922 (2008);<br></p>Formule :C19H28N2O4·ClHCouleur et forme :NeatMasse moléculaire :384.90Clozapine-d8
CAS :Produit contrôlé<p>Applications An antipsychotic.A representative lot was 92% d8, 8% d7.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Stille, et al: Farnaco, Ed. Prat., 26, 603 (1971), Hane, J.M., et al.: Psychopharmacol. Bull., 24, 62 (1988), Meltzer, H.Y.: J. Clin. Psychiatry, 55, Suppl. B, 47 (1994)<br></p>Formule :C18H11D8ClN4Couleur et forme :Light Yellow To YellowMasse moléculaire :334.871-(9H-Carbazol-4-yloxy)-3-(propan-2-ylamino)propan-2-ol
CAS :Produit contrôléFormule :C18H22N2O2Couleur et forme :Colourless Crystalline PowderMasse moléculaire :298.38rac-4-Hydroxy Propranolol Hydrochloride
CAS :<p>Stability Hygroscopic<br>Applications rac-4-Hydroxy Propranolol Hydrochloride is a metabolite of Propranolol.<br>References Walle, T., et al.: Drug Metab. Dispos., 13, 204 (1985), Mason, R., et al.: J. Med. Chem., 34, 869 (1991), Anderson, R., et al.: Biochem. Pharmacol., 52, 341 (1996), Hung, D., et al.: J. Pharmacol. Exp. Ther., 297, 780 (2001),<br></p>Formule :C16H21NO3·ClHCouleur et forme :NeatMasse moléculaire :311.802-Keto Crizotinib
CAS :Produit contrôlé<p>Applications 2-Keto Crizotinib is an impurity of Crizotinib (C785000), a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK). Crizotinib is a potential antitumor agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formule :C21H20Cl2FN5O2Couleur et forme :NeatMasse moléculaire :464.32Dehydro Aripiprazole-d8 Hydrochloride
CAS :Produit contrôléFormule :C232H8H17Cl2N3O2·ClHCouleur et forme :Off White SolidMasse moléculaire :490.88Noradrenalone Hydrochloride
CAS :Produit contrôlé<p>Applications Noradrenalone Hydrochloride is an intermediate of Norepinephrine (N674500), an antagonist of dibutyryl cyclic AMP in the regulation of narcosis. Norepinephrine modulates human dendritic cell activation by altering cytokine release.<br>References Strobel, G., et. al.: Eur. J. Biochem., 176, 397 (1988); Piguet, P., et al.: J. Exp. Med., 173, 673 (1991); Hosoi, J., et al.: Nature, 363, 159 (1993); Elenkov, I., et al.: Pharmacol. Rev., 52, 595 (2000); Kaplan, D., et al.: Immunity, 23, 611 (2005)<br></p>Formule :C8H10ClNO3Couleur et forme :Dark Yellow To Dark BrownMasse moléculaire :203.62Dimetridazole-d3
CAS :Produit contrôlé<p>Applications Labelled Dimetridazole (D479660). An antihistomonal agent. Antiprotozoal (Histomonas).<br>References Butler, K., et al.: J. Med. Chem., 10, 891 (1967), Mitrovic, M., et al.:; Antimicrob. Agents Chemother., 445, 1968, Mitrovic, M., et al.: Poult. Sci., 49, 86 (1970),<br></p>Formule :C52H3H4N3O2Couleur et forme :Off-WhiteMasse moléculaire :144.15(R)-Timolol
CAS :Produit contrôlé<p>Impurity Timolol EP Impurity A; Timolol BP Impurity A; Timolol USP Related Compound A<br>Applications (R)-Timolol (Timolol EP Impurity A; Timolol BP Impurity A; Timolol USP Related Compound A) is an antihypertensive agent that increases ocular blood flow and reduces intraocular pressure. (R)-Timolol is an β-adrenergic blocking agent that binds only to nonspecific sites in the particulate fraction of the heart, lungs, and brain.<br>References Rotmensch, H. et al.: J. Clinical. Pharmacol., 33, 544 (1993); Chiou, G. & Chen. Y., J. Ocular. Pharmacol., 8, 183 (1992); Chiou, G. et al.: J. Ocular. Pharmacol., 6, 23 (1990); Tocco, D. et al.: Drug Met. Disposit., 4, 323 (1976)<br></p>Formule :C13H24N4O3SCouleur et forme :NeatMasse moléculaire :316.42(1S,2S,3R,5S)-3-[[3-[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-7-yl]amino]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol
CAS :Produit contrôléFormule :C23H28F2N6O4SCouleur et forme :NeatMasse moléculaire :522.57Ethionamide-d3
CAS :Produit contrôlé<p>Applications Ethionamide-d3 is the isotope labelled analogue of Ethionamide (E890420), a antibacterial (tuberculostatic) agent.<br>References Banerjee, A., et al.: Science, 263, 227 (1994), Newton, G., et al.: J. Bacteriol., 178, 1990 (1996), Baulard, A., et al.: J. Biol. Chem., 275, 28326 (2000), Koledin, T., et al.: Arch. Microbiol., 178, 331 (2002), Cardoso, R., et al.: Antimicrob. Agents Chemother., 48, 3373 (2004),<br></p>Formule :C8H7D3N2SCouleur et forme :NeatMasse moléculaire :169.26(S)-Phenylephrine Hydrochloride
CAS :Formule :C9H13NO2·ClHCouleur et forme :NeatMasse moléculaire :203.673-Hydroxy-2-pyrone
CAS :Produit contrôlé<p>Applications 3-Hydroxy-2-pyrone<br></p>Formule :C5H4O3Couleur et forme :NeatMasse moléculaire :112.083-Hydroxy Loratadine
CAS :Produit contrôlé<p>Applications An intermediate for the preparation of 3-Hydroxy Desloratadine.<br></p>Formule :C22H23ClN2O3Couleur et forme :NeatMasse moléculaire :398.884-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-butanol
CAS :Produit contrôlé<p>Applications 4-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-butanol is a diphenylpyrazine derivative which belongs to a class of prostacyclin receptor agonists. It is an impurity of Selexipag (S253150) that is a potential drug for the treatment of various vascular disorders such as pulmonary arterial hypertension and arteriosclerosis obliterans.<br>References Asaki, T., et al.: Bioorg. Med. Chem., 15, 6692 (2007); Kuwano, K., et al.: J. Pharm. Exp. Ther., 322, 1181 (2007);<br></p>Formule :C23H27N3OCouleur et forme :NeatMasse moléculaire :361.48Tadalafil Ketolactam (>90%)
CAS :Produit contrôlé<p>Stability Hygroscopic, Unstable in Solution<br>Applications Tadalafil Ketolactam is a Tadalafil (T004500) impurity.<br></p>Formule :C22H19N3O6Degré de pureté :>90%Couleur et forme :NeatMasse moléculaire :421.4028Tipranavir
CAS :<p>Applications Nonpeptidic HIV protease inhibitor (NPPI). Antiviral.<br>References Poppe, S.M., et al.: Antimicrob. Agents Chemother., 41, 1058 (1997), McGregor, T.R., et al.: HIV Clin. Trials, 5, 371 (2004), Boffito, M., et al.: J. Clin. Pharmacol., 46, 130 (2006),<br></p>Formule :C31H33F3N2O5SCouleur et forme :NeatMasse moléculaire :602.661-Methyl-4-[5-(2-methylsulfamoylethyl)-1H-indol-3-yl]pyridinium Chloride
Produit contrôlé<p>Impurity Naratriptan pyridinium Impurity<br>Stability Hygroscopic<br>Applications Naratriptan (N378730) impurity.<br></p>Formule :C17H20ClN3O2SCouleur et forme :NeatMasse moléculaire :365.88Felodipine Ester Lactone
CAS :Produit contrôlé<p>Applications Felodipine Ester Lactone is an intemediate used in the synthesis of Dehydro Felodipine Ester Lactone (D229690), which is a metabolite of Felodipine (F232375).<br>References Wang, S.X. et al.: J. Pharmacol. Exp. Therap., 250, 632 (1989); Baeaernhielm, C. et al.: Drug Metab. Disp., 14, 613 (1986);<br></p>Formule :C17H15Cl2NO4Couleur et forme :NeatMasse moléculaire :368.214-[2-(Dimethylamino)ethoxy]benzonitrile
CAS :Produit contrôléFormule :C11H14N2OCouleur et forme :NeatMasse moléculaire :190.242Omeprazole Sulfone
CAS :<p>Impurity USP Omeprazole Related Compound A<br>Applications A metabolite of Omeprazole.<br></p>Formule :C17H19N3O4SCouleur et forme :White To Light BrownMasse moléculaire :361.42Urapidil Hydrochloride
CAS :<p>Applications α1-Adrenergic antagonist; derivative of Uracil (U801000). Antihypertensive.<br>References Eltze, M., et al.: Eur. J. Pharmacol., 59, 1 (1979), Barankay, A., et al.: Arzneim.-Forsch., 31, 849 (1981), Belz, G.G., et al.: Clin. Pharmacol. Ther., 37, 48 (1985),<br></p>Formule :C20H29N5O3·ClHCouleur et forme :NeatMasse moléculaire :423.94(S)-Naproxen Acyl-β-D-glucuronide
CAS :<p>Applications A metabolite of Naproxen.<br>References Boynton, C., et al.: J. Clin. Pharmacol., 28, 512 (1988), Jin, C., et al.: J. Pharmacol. Exp. Ther., 264, 475 (1993),King, C., et al.: Toxicol. Sci., 61, 49 (2001), Aresta, A., et al.: J. Pharm. Biomed. Anal., 39, 643 (2005),<br></p>Formule :C20H22O9Couleur et forme :NeatMasse moléculaire :406.38Bis-[Des(5-Chloro-2-carboxythienyl)] Rivaroxaban Phthalamide
CAS :Produit contrôléFormule :C36H36N6O10Couleur et forme :NeatMasse moléculaire :712.71Sitagliptin-d4 Phosphate
CAS :Produit contrôlé<p>Applications A trizolopyrazine dipeptidyl peptidase IV inhibitor. It has recently been approved for the therapy of type II diabetes.<br>References Kim, D., et al.: J. Med. Chem., 48, 141 (2005), Ahren, B., et al.: Eur. J. Pharmacol., 521 164 (2005), Bergman, A., et al: Clin. Ther., 28, 55 (2006).<br></p>Formule :C162H4H11F6N5O·H3O4PCouleur et forme :Off-WhiteMasse moléculaire :509.333-Methylisoquinoline
CAS :Formule :C10H9NDegré de pureté :95.0%Couleur et forme :Chunks,Crystalline PowderMasse moléculaire :143.1894-(3-((4-Chloro-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine
CAS :Degré de pureté :95+%Couleur et forme :SolidMasse moléculaire :337.79998779296875(S)-2-Aminobutanoic Acid Hydrochloride
CAS :Produit contrôlé<p>Applications (S)-2-Aminobutanoic Acid Hydrochloride is an intermediate in the synthesis of Levetiracetam (L331500), which is used as an anticonvulsant.<br>References Gower, A.J., et al.: Eur. J. Pharmacol., 222, 193 (1992); Kasteleijn-Noist Trenite, D.G.A., et al.: Epilepsy Res., 25, 225 (1996); Patsalos, P.N., et al.: Pharmacol. Ther., 85, 77 (2000)<br></p>Formule :C4H10ClNO2Couleur et forme :NeatMasse moléculaire :139.58L-Lysine Clonixinate
CAS :<p>Applications L-Lysine Clonixinate is a non-morphinic andalgesic.<br>References Krymchantowski, A., et al.: Curr. Ther. Res., 64, 505 (2003), Di Girolamo, G., et al.: Brit. J. Pharmacol., 141, 1234 (2004),<br></p>Formule :C13H11ClN2O2·C6H14N2O2Couleur et forme :Off WhiteMasse moléculaire :408.884-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluorobenzamide
CAS :Formule :C20H14F4N4O2SCouleur et forme :NeatMasse moléculaire :450.41Des(R)-3-Aminopiperidine Linagliptin
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications 7-(2-Butyn-1-yl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione is an impurity of Linagliptin (L465900), a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.<br>References Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011); Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011);<br></p>Formule :C20H18N6O2Couleur et forme :NeatMasse moléculaire :374.4Ezetimibe Phenoxy β-D-Glucuronide
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Phase-II metabolite of Ezetimibe, an antihyperlipoproteinemic. A Cholesterol absorption inhibitor.This compound is very hygroscopic. Handle with care.<br>References van Heek, M., at al.: J. Pharmacol. Exp. Ther., 283, 157 (1997), van Heek, M., at al.: Brit. J. Pharmacol., 129, 1748 (2000)<br></p>Formule :C30H29F2NO9Couleur et forme :White To Light BrownMasse moléculaire :585.55Ethyl 3-(4-Bromophenyl)-1-methyl1H-pyrazole-5-carboxylate
CAS :Formule :C13H13BrN2O2Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :309.1631-(4-Fluorophenyl)-4-(4-(pyridin-2-yl)piperazin-1-yl)butan-1-one
CAS :Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :327.40301513671875Cabozantinib L-Malate Salt
CAS :Produit contrôlé<p>Applications Cabozantinib is a small molecule C-Met modulator. Cabozantinib acts as a potent multitargeted VEGFR2, Met, FLT3, Tie2, Kit and Ret inhibitor with IC50 of 0.035, 1.8, 14.4, 14.3 and 4.6 nM for VEGFR2, Met, FLT3, Tie2 and Kit, respectively. Cabozantinib shows dose-dependent inhibition of tumor growth and tumor regression, associated with disruption of the tumor vasculature and extensive tumor cell apoptosis.<br>References Camp, R., et al.: Cancer, 86, 2259 (1999), Morello, S., et al.: J. Cell Physiol., 189, 285 (2001), Zhang, Y., et al.: Oncogene, 21, 217 (2002), Wells, S., et al.: J. Clin. Oncol., 28, 767 (2010),<br></p>Formule :C28H24FN3O5·C4H6O5Couleur et forme :NeatMasse moléculaire :635.597-Methoxy-1-naphthaleneethanamine Hydrochloride
CAS :Produit contrôléFormule :C13H15NO·ClHCouleur et forme :NeatMasse moléculaire :237.734-[4-[(5S)-5-Phthalimidomethyl-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone
CAS :Produit contrôléFormule :C22H19N3O6Couleur et forme :NeatMasse moléculaire :421.40Trimetazidine N-Carboxylic Acid Ethyl Ester
CAS :Produit contrôlé<p>Impurity Trimetazidine EP impurity H<br>Applications Trimetazidine N-Carboxylic Acid Ethyl Ester is impurity of Trimetazidine (T795610). Trimetazidine impurity H.<br>References Szwed, H., et al.: Clin. Drug Invest., 19, 1 (2000), Thoppil, S., et al.: J. Pharm. Biomed. Anal., 25, 15 (2001), Wang, Z., et al.: Pharmazie, 62, 27 (2007),<br></p>Formule :C17H26N2O5Couleur et forme :NeatMasse moléculaire :338.40Niclosamide Monohydrate
CAS :Produit contrôléFormule :C13H8Cl2N2O4·H2OCouleur et forme :WhiteMasse moléculaire :345.135Panobinostat Carboxylic Acid Methyl Ester Hydrochloride
CAS :Formule :C22H25ClN2O2Couleur et forme :Neat7-Hydroxy Chlorpromazine Hydrochloride
CAS :<p>Impurity Chlorpromazine 7-Hydroxy Impurity<br>Stability Hygroscopic<br>Applications 7-Hydroxychlorpromazine is the 7-hydroxy analogue and a major metabolite of the atypical antipsychotic Chlorpromazine (C424750).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jori, A. et al.: Int. J. Neuropharmacol., 5, 435 (1966); Shavit, S. et al.: Comm. Psychopharmacol., 4, 495 (1980);<br></p>Formule :C17H19ClN2OS·HClCouleur et forme :White To Light PurpleMasse moléculaire :371.32(Z)-2-(5-Fluoro-2-methyl-1-(4-(methylsulfinyl)benzylidene)-1H-inden-3-yl)acetic acid
CAS :Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :356.4100036621094Nintedanib Esylate
CAS :Formule :C31H33N5O4·C2H6O3SCouleur et forme :Light YellowMasse moléculaire :649.76Levetiracetam Carboxylic Acid
CAS :Produit contrôléFormule :C8H13NO3Couleur et forme :White To Off-WhiteMasse moléculaire :171.19Indazole-3-carboxylic Acid
CAS :Produit contrôlé<p>Applications Indazole-3-carboxylic Acid is an indole derivatives useful in treatment of pain and inflammation.<br>References Khanna P., et al.: Biochemistry, 40, 1441 (2001);<br></p>Formule :C8H6N2O2Couleur et forme :NeatMasse moléculaire :162.145(S)-Ibrutinib
CAS :Produit contrôlé<p>Stability Light Sensitive<br>Applications (S)-Ibrutinib is a highly selective Bruton’s tyrosine kinase (Btk) irreversible inhibitor.<br>References Pan, Z., et. al.: ChemMedChem, 2, 58 (2007)<br></p>Formule :C25H24N6O2Couleur et forme :NeatMasse moléculaire :440.5Methyl 3-((phenoxycarbonyl)amino)thiophene-2-carboxylate
CAS :Degré de pureté :95%Masse moléculaire :277.2900085449219Saxagliptin
CAS :Produit contrôlé<p>Stability Temperature Sensitive<br>Applications Saxagliptin is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.<br>References Feng, J., et al.: J. Med. Chem., 50, 2297 (2007), Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008), Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008),<br></p>Formule :C18H25N3O2Couleur et forme :White SolidMasse moléculaire :315.41Daprodustat
CAS :<p>Applications Daprodustat is a novel HIF (Hypoxia inducible factor)-prolyl hydroxylase inhibitor.<br>References Olson, E., et al.: Vasc. Med., 19, 473 (2014);<br></p>Formule :C19H27N3O6Couleur et forme :Off-WhiteMasse moléculaire :393.431-(4-(Trifluoromethoxy)phenyl)-2-thiourea
CAS :Produit contrôléFormule :C8H7F3N2OSCouleur et forme :NeatMasse moléculaire :236.21O-Desmethyl Diltiazem Hydrochloride
CAS :Produit contrôlé<p>Impurity Diltiazem EP Impurity C (HCl)<br>Applications A metabolite of Diltiazem (D460620), an antianginal, antihypertensive pharmaceutical. Diltiazem EP Impurity C (HCl).<br>References Li, R., et al.: J. Med. Chem., 35, 3246 (1992),<br></p>Formule :C21H25ClN2O4SCouleur et forme :NeatMasse moléculaire :436.955’-Carboxy Meloxicam
CAS :Produit contrôléFormule :C14H11N3O6S2Couleur et forme :NeatMasse moléculaire :381.382-Ethylbenzofuran
CAS :Produit contrôlé<p>Applications 2-Ethylbenzofuran is used in the synthesis of benzofurans as potential antianginal agents. They are also used in the preparation of 2-arylpyridines that are used in the synthesis of complexes with physical properties.<br>References Goldenberg, C. et al.: Eur. j. Med. Chem., 12, 81 (1977); Baloch, M. et al.: Eur. J. Med. Chem., 2012, 4454 (2012);<br></p>Formule :C10H10OCouleur et forme :NeatMasse moléculaire :146.19Apixaban
CAS :<p>Applications A potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.<br>References Luettgen, J. M., et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T., et al.: J. Thromb. Thrombol., 31, 310 (2011); Barrett, Y. C., et al.: Thromb. Haemos., 105, 181 (2011);<br></p>Formule :C25H25N5O4Couleur et forme :White To Off-WhiteMasse moléculaire :459.50Tetramethylurea
CAS :<p>Applications Tetramethylurea is an excellent solvent for organic substances, in particular aromatic compounds.<br>References Lüttringhaus, A., et al.: Angew. Chem. Int. Ed. Engl., 3, 260 (1964)<br></p>Formule :C5H12N2OCouleur et forme :NeatMasse moléculaire :116.16Ramelteon
CAS :Produit contrôlé<p>Applications Melatonin MT1/MT2 receptor agonist. Sedative, hypnotic.<br>References Yukuhiro, N., et al.: Brain Res., 59, 1027 (2004), Cajochen, C., et al.: Curr. Opin. Invest. Drugs, 6, 114 (2005), Kato, K., et al.: Neuropharmacology, 48, 301 (2005),<br></p>Formule :C16H21NO2Couleur et forme :NeatMasse moléculaire :259.341-Benzhydrylpiperazine
CAS :Produit contrôléFormule :C17H20N2Couleur et forme :White To BeigeMasse moléculaire :252.352,2-Diphenylhydantoic Acid
CAS :<p>Impurity Phenytoin USP Related Compound B<br>Applications 2,2-Diphenylhydantoic Acid is metabolite of Phenytoin, an anticonvulsant. Phenytoin USP Related Compound B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Van Espen, J., et al.: J. De. Pharma. De. Belgique., 7, 451 (1952); Stella, V., et al.: J. Org. Chem., 38, 1527 (1973);<br></p>Formule :C15H14N2O3Couleur et forme :NeatMasse moléculaire :270.28Etomidate
CAS :Produit contrôlé<p>Applications Etomidate is a hypnotic. Neuroprotective & Neuroresearch Products<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Goetz, E., et al.: Anaesthesist, 23, 331 (1974), Chang, Z. L., et al.: Anal. Profiles Drug Subs., 12, 191 (1983),<br></p>Formule :C14H16N2O2Couleur et forme :Off-WhiteMasse moléculaire :244.29Methocarbamol-d5
CAS :Produit contrôléFormule :C112H5H10NO5Couleur et forme :NeatMasse moléculaire :246.27Ertugliflozin
CAS :Produit contrôléFormule :C22H25ClO7Couleur et forme :NeatMasse moléculaire :436.885-Methyl-2-phenoxypyridine
CAS :Produit contrôléFormule :C12H11NOCouleur et forme :NeatMasse moléculaire :185.23Dimethylaminomethylfurylmethylthioethyl Ranitidine
CAS :Produit contrôlé<p>Impurity Ranitidine EP impurity A<br>Applications Dimethylaminomethylfurylmethylthioethyl Ranitidine (Ranitidine EP impurity A) is a Ranitidine (R120000) impurity.<br>References Evans, M., et al.: J. Pharm. Biomed. Anal., 7, 1 (1989), Mellors, J., et al.: Anal. Chem., 76, 5441 (2004),<br></p>Formule :C22H35N5O4S2Couleur et forme :NeatMasse moléculaire :497.67Hexametazidine
CAS :Produit contrôlé<p>Impurity Trimetazidine dihydrochloride EP impurity B<br>Applications Hexametazidine is an impurity of Trimetazidine (T795610). Trimetazidine impurity B. Hexametazidine can protect the myocardium from injury by ischemia and reperfusion.<br></p>Formule :C24H34N2O6Couleur et forme :NeatMasse moléculaire :446.54Palbociclib N-Aldehyde
CAS :Produit contrôlé<p>Applications Palbociclib N-Aldehyde is an intermediate in synthesizing Palbociclib N-β-D-Glucuronide Sodium Salt (P139910), a derivative of Palbociclib (P139900) which is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.<br>References Finn, R., et al.: Breast Cancer Res., 11, 5 (2009)<br></p>Formule :C25H29N7O3Couleur et forme :NeatMasse moléculaire :475.54Methyl 4-Acetamido-5-bromo-2-methoxybenzoate
CAS :Produit contrôlé<p>Applications Methyl 4-Acetamido-5-bromo-2-methoxybenzoate is an impurity of bromopride (B686645), which is an antimetic.<br>References Fontaine, J., et al.: Arch. Int. Pharmacodyn. Ther., 213, 322 (1975), Lucker, P.W., et al.: Arzneim.-Forsch., 33, 453 (1983)<br></p>Formule :C11H12BrNO4Couleur et forme :Off-WhiteMasse moléculaire :302.122,6-Di(1H-pyrazol-1-yl)-4,4'-bipyridine
CAS :Degré de pureté :98%Masse moléculaire :288.31399536132816-Bromo-4-phenyl-1H-quinazolin-2-one
CAS :Degré de pureté :95.0%Masse moléculaire :301.143005371093754-Desmethyl-4-ethylimidazolyl Nilotinib
CAS :Produit contrôléFormule :C29H24F3N7OCouleur et forme :Light Beige To Light BrownMasse moléculaire :543.54Propiconazole
CAS :Produit contrôlé<p>Applications Propiconazole is a systemic foliar fungicide. Agricultural fungicide. Useful in cannabis testing kits as a component of pesticide mixes (P698235).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Child, R., et al.: Plant Growth Regul., 13, 203 (1993), Jaleel, C., et al.: Plant Sci., 171, 271 (2006), Jaleel, C., et al.: Pestic Biochem. Physiol., 91, 170 (2008),<br></p>Formule :C15H17Cl2N3O2Couleur et forme :YellowMasse moléculaire :342.22Levofloxacin N-oxide
CAS :Produit contrôlé<p>Impurity Oxifloxacin EP Impurity F<br>Applications Levofloxacin N-oxide is an impurity of Ofloxacin (O245750), which is a fluorinated quinolone antibacterial.<br>References Horstkotter, C., et al.: J. Chromatography Biomed. Sci. Appli., 754, 169 (2001); Monk, J.P., et al.: Drugs, 33, 346 (1987), Drlica, K., Curr. Opin. Microbiol. 2, 504 (1990)<br></p>Formule :C18H20FN3O5Couleur et forme :NeatMasse moléculaire :377.372-Chloropyridine
CAS :Produit contrôlé<p>Applications 2-Chloropyridine (2-CPY) has been identified as a trace organic chemical in process streams, wastewater and even drinking water. Furthermore, it appears to be formed as a secondary pollutant during the decomposition of specific insecticides. 2-CPY was found to be genotoxic agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Demsia, G., et al.: Mutat. Res., 634, 32 (2007), Stapleton, D., et al.: Water Res., 43, 3964 (2009),<br></p>Formule :C5H4ClNCouleur et forme :NeatMasse moléculaire :113.54Hydroxy-2-phenylpropyl Carbamate
CAS :Produit contrôlé<p>Applications Hydroxy-2-phenylpropyl Carbamate is an impurity in the synthesis of Felbamate (F231000), an antiepileptic, structurally similar to meprobamate.<br>References Swinyard, E.A., et al.: Epilepsia, 27, 27 (1986), Remmel, R.P., et al.: Ther. Drug Monit., 12, 90 (1990), Sofia, R.D., et al.: Epilepsy Res. Suppl., 3, 103 (1991),<br></p>Formule :C10H13NO3Couleur et forme :NeatMasse moléculaire :195.22aR,4S-Brivaracetam
CAS :Produit contrôléFormule :C11H20N2O2Couleur et forme :NeatMasse moléculaire :212.29Nifedipine-d6
CAS :Produit contrôlé<p>Applications Used as an antihypertensive and antianginal. A labelled dihydorpyridine calcium channel blocker.<br>References Ali, S.L., et al.: Anal. Profiles Drug Subs., 18, 221 (1989), Soons, P.A., et al.: J. Pharm. Biomed. Anal., 9, 475 (1991), Brown, M.J., et al.: Lancet, 356, 366 (2000),<br></p>Formule :C172H6H12N2O6Couleur et forme :YellowMasse moléculaire :352.37N-Desmethyl Clozapine-d8
CAS :Produit contrôlé<p>Applications A major labelled metabolite of clozapine. A potent and selective 5-HT2C serotonin receptor antogonist.<br>References Kuoppamaki, M. et al.: Eur. J. Pharm. Mol. Pharm. Sect., 245, 179 (1993), Olessen, O.V., et al.: J. Chromatog., 622, 39 (1993), Pirmohamed, M., et al.: J. Pharmacol. Exp. Ther., 272, 984 (1995)<br></p>Formule :C172H8H9ClN4Couleur et forme :Light YellowMasse moléculaire :320.85Phenylbutazone-d9
CAS :Produit contrôléFormule :C192H9H11N2O2Couleur et forme :White To Light BrownMasse moléculaire :317.43Levofloxacin Ethyl Ester
CAS :Produit contrôlé<p>Impurity Levofloxacin USP Related Compound C<br>Applications Levofloxacin Ethyl Ester (Levofloxacin USP Related Compound C) is an impurity of Levofloxacin (L360000).<br>References Lalitha Devi, M. et al.: J. Pharrm. Biomed. ANal., 50, 710 (2009); Mehta, J. et al.: Int. J. PharmTech Res., 2, 1932 (2010);<br></p>Formule :C20H24FN3O4Couleur et forme :White To Off-WhiteMasse moléculaire :389.423,5,6-Trihydroxy-1-isopropylindole
CAS :Produit contrôlé<p>Applications 3,5,6-Trihydroxy-1-isopropylindole is an impurity of Isoproterenol (I874200), which is a non-selective beta-adrenergic agonist. Isoproterenol is used in the treatment of bradycardia; bronchodilator.<br>References Kikkawa, H. et al.: Biol. Pharmac. Bull., 17, 1047 (1994); Kral, P. et al.: Psychopharmacologia, 26, 79 (1972); Giles, R.E. et al.: J. Pharmacol. Exp. Ther., 186, 472 (1973);<br></p>Formule :C11H13NO3Couleur et forme :NeatMasse moléculaire :207.2267-(But-2-yn-1-yl)-3-methyl-8-(methylamino)-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione
CAS :Produit contrôlé<p>Applications 7-(But-2-yn-1-yl)-3-methyl-8-(methylamino)-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione is an impurity of Linagliptin (L465900), a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.<br>References Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011); Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011);<br></p>Formule :C21H21N7O2Couleur et forme :NeatMasse moléculaire :403.437N-(p-Chlorobenzoyl)-p-anisidine
CAS :Produit contrôlé<p>Applications N-(p-Chlorobenzoyl)-p-anisidine is a COX-1 inhibitor analgesics that do not cause gastric damage.<br>References Kakuta, H., et al.: J. Med. Chem., 51, 2400 (2008);<br></p>Formule :C14H12ClNO2Couleur et forme :White To Off-WhiteMasse moléculaire :261.7Salbutamon Hydrochloride
CAS :<p>Impurity Salbutamol EP Impurity J<br>Applications Salbutamon Hydrochloride (Salbutamol EP Impurity) is a related impurity of Albuterol (A514500) (Salbutamol) (EP).<br>References Price, A., et al.: Drugs, 38, 77 (1989), Beaulieu, N., et al.: J. Pharm. Biom. Anal., 8, 583 (1990), Sagar, K., et al.: J. Pharm. Biomed. Anal., 11, 533 (1993),<br></p>Formule :C13H19NO3·ClHCouleur et forme :NeatMasse moléculaire :273.76N-Nitrosonadolol
CAS :Formule :C17H26N2O5Couleur et forme :White To Off-WhiteMasse moléculaire :338.42-(3-Bromo-5-chlorophenyl)-4,6-diphenyl-1,3,5-triazine
CAS :Degré de pureté :97%Masse moléculaire :422.7099914550781(-)-trans-4-[4-(4’-Fluorophenyl)-3-piperidinylmethoxy]-2-methoxyphenol(Paroxetine metabolite)
CAS :Produit contrôléFormule :C19H22FNO3Couleur et forme :NeatMasse moléculaire :331.38(S)-Naproxen-d3
CAS :Produit contrôlé<p>Applications (S)-Naproxen-d3 is the labeled analogue of (S)-Naproxen (N377520), an anti-inflammatory, analgesic, antipyretic. A non-steroidal anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Harrison, I.T., et al.: J. Med. Chem., 13, 203 (1970)<br></p>Formule :C142H3H11O3Couleur et forme :NeatMasse moléculaire :233.28Dasatinib N-Oxide
CAS :<p>Applications An oxidative metabolite of Dasatinib (M5 metabolite). It is a COVID19-related research product.<br>References Cashman, J.R., et al.: Chem. Res. Toxicol., 8, 165 (1995), Aasmoe, L., et al.: Toxicol. Appl. Pharmacol., 150, 86 (1998), Galetin, A., et al.: J. Pharmacol. Exp. Ther., 314, 180 (2005), Christopher, L.J., et al.: Drug Metab. Dispos., 36, 1357 (2008),<br></p>Formule :C22H26ClN7O3SCouleur et forme :NeatMasse moléculaire :504.003-Methyl-5-hydroxypyrazole
CAS :Formule :C4H6N2ODegré de pureté :95%Couleur et forme :White powderMasse moléculaire :98.1053-CHLORO-5-PYRIDYL-6-PHENYLPYRIDAZINE
CAS :Degré de pureté :95.0%Masse moléculaire :267.72000122070312-Methyl-N-[3-(trifluoromethyl)phenyl]propanamide
CAS :Produit contrôléFormule :C11H12F3NOCouleur et forme :NeatMasse moléculaire :231.21
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