Dérivés de Quinazoline et de Quinoléine
Les quinazolines et les quinoléines sont des composés hétérocycliques azotés à structure aromatique qui jouent un rôle clé dans la synthèse de médicaments à activité anticancéreuse, antimicrobienne et anti-inflammatoire. Leurs dérivés présentent des modifications structurelles qui optimisent leur biodisponibilité et leur sélectivité, permettant ainsi le développement de nouveaux principes actifs pour diverses applications thérapeutiques. Ces composés sont utilisés dans la fabrication d’API destinés au traitement du cancer, des infections, des maladies neurodégénératives et cardiovasculaires. De plus, les dérivés de quinazoline et de quinoléine sont essentiels dans la recherche d’inhibiteurs enzymatiques et dans la conception de molécules bioactives innovantes.
Chez CymitQuimica, nous proposons des dérivés de quinazoline et de quinoléine de haute pureté pour des applications en synthèse chimique, développement pharmaceutique et biotechnologie.
65941 produits trouvés pour "Dérivés de Quinazoline et de Quinoléine"
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3,5-Bis(chloromethyl)pyridine Hydrochloride
CAS :Produit contrôlé<p>Stability Unstable in Aqueous Solution<br>Applications 3,5-BIS(CHLOROMETHYL)PYRIDINE HCL (cas# 1210824-61-5) is a useful research chemical.<br></p>Formule :C7H7Cl2N•HClCouleur et forme :NeatMasse moléculaire :212.5Levetiracetam-d6
CAS :Produit contrôlé<p>Applications The labelled (S)-enantiomer of Etiracetam (E932970) and the ethyl analog of Piracetam (P500800). Used as an anticonvulsant.<br>References Gower, A.J., et al.: Eur. J. Pharmacol., 222, 193 (1992); Kasteleijn-Noist Trenite, D.G.A., et al.: Epilepsy Res., 25, 225 (1996); Patsalos, P.N., et al.: Pharmacol. Ther., 85, 77 (2000),<br></p>Formule :C82H6H8N2O2Couleur et forme :BeigeMasse moléculaire :176.252-(2-Methoxyethyl)phenol
CAS :Produit contrôlé<p>Applications 2-(2-Methoxyethyl)phenol is used as a stabilizer in the preparation of polysiloxane based coating compounds with good stability.<br></p>Formule :C9H12O2Couleur et forme :NeatMasse moléculaire :152.192-Cyano-3-(3-chlorophenylethyl)pyridine
CAS :Produit contrôléFormule :C14H11ClN2Couleur et forme :NeatMasse moléculaire :242.705-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione
CAS :Produit contrôlé<p>Applications 5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione is an impurity of the DPP-IV inhibitor Sitagliptin (S491000).<br>References Ye, F. et al.: Hech. Huax., 18, 767 (2010); Ahn, J.H, et al.: Bioorg. Med. Chem. Lett., 17, 2622 (2007);<br></p>Formule :C14H11F3O5Couleur et forme :NeatMasse moléculaire :316.23S-(+)-Atomoxetine Hydrochloride
CAS :Produit contrôlé<p>Impurity Atomoxetine EP Impurity B<br>Applications ent S-(+)-Atomoxetine Hydrochloride (Atomoxetine EP Impurity B) is an enatiomer of Atomoxetine, a Norepinephrine uptake blocker.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Robertson, D., et al.: J. Med. Chem., 31, 1412 (1988), Hwamg, et al.: Neurosci. Lett., 265, 151 (1999),<br></p>Formule :C17H21NO·ClHCouleur et forme :NeatMasse moléculaire :291.82Cinitapride
CAS :<p>Applications A novel prokinetic benzamide-stimulating gastrointestinal motility agent and antiucer agent. It acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors (1,2,3).<br>References (1) Alarcon de la Lastra, C. et al.: Pharmacol, 54, 193 (1997)(2) Robert, M. et al.: Drug Metab. Disp., 35, 1149 (2007)(3) Alarcon de la Lastra, C. et al.: Inflam. Res., 47, 131 (1998)<br></p>Formule :C21H30N4O4Couleur et forme :NeatMasse moléculaire :402.492-Nitroso Riluzole
Produit contrôlé<p>Applications 2-Nitroso Riluzole is an impurity of Riluzole (R510000); is a neuroprotective agent. Modulates glutamatergic transmission. A glutamate release inhibitor. An anticonvulsant. Neuroprotective agent.<br>References Mizoule, J., et al.: Neuropharmacology, 24, 767 (1985), Wahl, F., et al.: Eur. J. Pharmacol., 230, 209 (1993) Bensimon, G., et al.: N. Engl. J. Med., 330, 585 (1994)<br></p>Formule :C8H3F3N2O2SCouleur et forme :Dark GreenMasse moléculaire :248.1824-Chlorophenothiazine
CAS :Produit contrôlé<p>Applications Intermediate in the preparation of Prochlorperazine (P755800) and related compound.<br></p>Formule :C12H8ClNSCouleur et forme :NeatMasse moléculaire :233.72(6S)-N6-[3-[[(6S)-2-Amino-4,5,6,7-tetrahydro-6-benzothiazolyl]amino]-1-ethyl-2-methylpropyl]-4,5,6,7-tetrahydro-2,6-benzothiazolediamine
CAS :<p>Stability Hygroscopic<br>Applications (6S)-N6-[3-[[(6S)-2-Amino-4,5,6,7-tetrahydro-6-benzothiazolyl]amino]-1-ethyl-2-methylpropyl]-4,5,6,7-tetrahydro-2,6-benzothiazolediamine can be obtained from (-)-2-Amino-6-propionamido-tetrahydrobenzothiazole (A628150) and is the byproduct of process for the preparation of pramipexole and salts thereof by reductive amination of (diamino)tetrahydrobenzothiazole with propanal. It is also a Pramaxo Impurity C.<br>References Deo, K., et al.: Indian Pat. Appl. (2015), IN 2013MU02843 A<br></p>Formule :C20H32N6S2Degré de pureté :>80%Couleur et forme :NeatMasse moléculaire :420.6383(1R,3R)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carbo
CAS :Produit contrôlé<p>Applications (1R,3R)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Hydrochloride is an impurity of Tadalafil (T004500) and is a β-carboline derivative. (1R,3R)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Hydrochloride can be used to produce Tadalafil.<br>References Lek Pharmaceuticals d.d., Slovenia: Eur. Pat. Appl., EP 2107059 A1 20091007 (2009)<br></p>Formule :C19H16N2O4·HClCouleur et forme :Off White SolidMasse moléculaire :372.8L-threo-Methylphenidate Hydrochloride
CAS :Produit contrôlé<p>Applications Controlled substance. CNS stimulant. The less potent threo-enantiomer of Methylphenidate. The threo enantomers have shown that the pharmacological activity residues predominantly in the d-threo enantiomer.<br>References Greenblatt, E.N., et al.: J. Pharmacol. Exp. Ther., 131, 115 (1961), Padmanabhan, G.R., et al.: Anal. Profiles Drug Subs., 10, 473 (1981), Kuczenski, R., et al.: J. Pharmacol. Exp. Ther., 296, 876 (2001), Pelham, W.E., et al.: J. Consult. Clin. Psychol., 61, 506 (1993), Srinivas, N.R., et al.: Pharm. Res., 10, 14 (1993),<br></p>Formule :C14H19NO2·ClHCouleur et forme :NeatMasse moléculaire :269.77Methyl 2-Methyl-3-nitrobenzoate
CAS :Produit contrôlé<p>Applications Methyl 2-methyl-3-nitrobenzoate is used as a reagent to synthesize Lenalidomide (L328000). Lenalidomide is a compound that exhibits antimyeloma, anticancer and immunomodulatory activity and is used to treat patients with B-cell malignancies.<br>References Balaev, A., et al.: Pharm. Chem. J., 46, 676 (2013); Chanan-Khan, A. & Cheson, B.: J. Clin. Oncol., 26, 1544 (2008); Dredge, K., et al.: Microvasc. Res., 69, 56, 69 (2005); Palumbo, A., et al.: J. Clin. Oncol., 25, 4459 (2007)<br></p>Formule :C9H9NO4Couleur et forme :NeatMasse moléculaire :195.174-[((2R)-Hydroxy-3-phthalimido)propylamine]phenyl-3-morpholinone
CAS :Produit contrôléFormule :C21H21N3O5Couleur et forme :NeatMasse moléculaire :395.41Sulcotrione-d7
CAS :Produit contrôléFormule :C14D7H6ClO5SCouleur et forme :Light Yellow SolidMasse moléculaire :335.81Selexipag D-Mannitol Ester (>80%)
Produit contrôléFormule :C31H41N3O8Degré de pureté :>80%Couleur et forme :NeatMasse moléculaire :583.68O-Desethyl Resiquimod-d6
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications O-Desethyl Resiquimod-d6 is the labelled analogue of O-Desethyl Resiquimod (D228575), which is derived from its parent compound Resiquimod (R144680), which is an imidazoquinoline derivative that acts as an immune response modifier. Resiquimod shows antitumor and antiviral activity and is used in the treatment of skin lesions such as herpes simplex virus. Resiquimod is a toll-like receptor 9 (TLR7) agonist.<br>References Wu, J.J. et al.: Antivir. Res., 64, 79 (2004); Fife, K.H. et al.: Antimicrob. Agents Chemother., 52, 477 (2008); Szeimies, R.M. et al.: Brit. J. Dermatol., 159, 205 (2008);<br></p>Formule :C15H12D6N4O2Couleur et forme :NeatMasse moléculaire :292.37Manidipine
CAS :Produit contrôlé<p>Applications A dihydropyridine calcium channel blocker. Antihypertensive.<br>References Meguro, K., et al.: Chem. Pharm. Bull., 33, 3787 (1985), Mizuno, K., et al.: Curr. Ther. Res., 52, 248 (1992)<br></p>Formule :C35H38N4O6Couleur et forme :Off White PowderMasse moléculaire :610.703-(2-Chloroethyl)-9-hydroxy-2-methyl-4H-Pyrido[1,2-a]pyrimidin-4-one Hydrochloride
CAS :Formule :C11H11ClN2O2·ClHCouleur et forme :NeatMasse moléculaire :275.13Afatinib N-Oxide
Produit contrôlé<p>Applications Afatinib N-Oxide is a derivative of Afatinib {BIBW 2992) (B377000), an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder. An anilino-quinazoline that irreversibly inhibits EGFR and HER2 kinase activity.<br>References Ham, J. et al.: Cancer Cell., 29, 159 (2016);<br></p>Formule :C24H25ClFN5O4Couleur et forme :White SolidMasse moléculaire :501.94Solifenacin EP Impurity A Nitroso Impurity
Produit contrôléFormule :C15H14N2OCouleur et forme :NeatMasse moléculaire :238.29Ebastine N-Oxide
CAS :<p>Stability -20°C Freezer<br>Applications Ebastine N-Oxide is an impurity of Ebastine (E320000). Ebastine impurity F and G (mixture of cis/trans).<br>References Yardley, J., et al.: J. Med. Chem., 33, 2899 (1990), Johnson, R., et al.: J. Antibiot., 49, 788 (1996), Takekawa, K., et al.: Xenobiotica, 31, 11 (2001), Chen, Z., et al.: Bioorg. Med. Chem. Lett., 14, 5275 (2004),<br></p>Formule :C32H39NO3Couleur et forme :NeatMasse moléculaire :485.6631-Oxo Everolimus (~80%)
Produit contrôléFormule :C53H81NO14Degré de pureté :~80%Couleur et forme :NeatMasse moléculaire :956.211H-1-Ethyl Candesartan
CAS :Produit contrôlé<p>Applications Candesartan (C175575) impurity.<br></p>Formule :C26H24N6O3Couleur et forme :WhiteMasse moléculaire :468.51N-(3-Chloro-6,11-dihydro-6-methyl-5,5-dioxidodibenzo[c,f][1,2]thiazepin-11-yl)-β-alanine-d4
CAS :Produit contrôléFormule :C17H13D4ClN2O4SCouleur et forme :NeatMasse moléculaire :384.87Furagin-13C3
Produit contrôlé<p>Applications Furagin-13C3 is the isotope labelled analogue of the antibacterial Furagin (F863000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Agace, W., et al.: J. Clin. Invest., 92, 780 (1993); Lawrenson, R., et al.: J. Antimicrob. Chemother., 48, 895 (2001); Dalhoff, A., et al.: Lancet Infect. Dis., 3, 359 (2003); Thumbikat, P., et al.: J. Immunol., 176, 3080 (2006);<br></p>Formule :C713C3H8N4O5Couleur et forme :NeatMasse moléculaire :267.17rac O-Desmethyl Naproxen-d3
CAS :Produit contrôléFormule :C13D3H9O3Couleur et forme :Dark RedMasse moléculaire :219.25Isopropyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide (Piroxicam Impurity I)
CAS :Produit contrôlé<p>Impurity Piroxicam EP Impurity I<br>Applications Piroxicam impurity I.<br>References Lombardino, J., et al.: J. Med. Chem., 14, 1171 (1971), Turck, D., et al.: Clin. Drug Invest., 9, 270 (1995),<br></p>Formule :C12H13NO5SCouleur et forme :NeatMasse moléculaire :283.3Ketoconazole N-Oxide
CAS :Produit contrôlé<p>Applications Ketoconazole N-Oxide is an impure analogue of Ketoconazole (K186000) which inhibits cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo. Antimetastatic and antineoplastic activity. Orally active 5-lipoxygenase and thromboxane synthase inhibitor.<br>References Lambert, A., et al.: Biochem. Pharmacol., 35, 3999 (1986), Van Wauwe, J.P. and Janssen, P.A.J., J. Med. Chem., 32, 2231 (1989), Nardone, P.A., et al.: . Surg. Res., 44, 425 (1988), Tucker, W.F.G., et al.: Br. Med. J., 293, 882 (1986)<br></p>Formule :C26H28Cl2N4O5Couleur et forme :Off-WhiteMasse moléculaire :547.43Pimavanserin N-Oxide
CAS :Produit contrôlé<p>Applications Pimavanserin N-Oxide is an impurity of Pimavanserin (P441800), a drug used in the treatment of Parkinson’s disease and psychosis.<br>References Snigdha, S., et al.: J. Pharmacol. Exper. Ther., 332, 622 (2010); Meltzer, H., et al.: Neuropsychopharmacol., 35, 881 (2010);<br></p>Formule :C25H34FN3O3Couleur et forme :NeatMasse moléculaire :443.55Indomethacin Ethyl Ester
CAS :Produit contrôléFormule :C21H20ClNO4Couleur et forme :Off-WhiteMasse moléculaire :385.84Ethyl 2-[N-[(2'-Cyanobiphenyl-4-yl)methyl]amino]-3-nitrobenzoate
CAS :<p>Applications Ethyl 2-[N-[(2'-Cyanobiphenyl-4-yl)methyl]amino]-3-nitrobenzoate is a useful reagent in synthesis of candesartan cilexitil.<br>References Zhu, Y., et al.: Zhongguo Yaowu Huaxue Zazhi, 13, 31 (2003); Cao, R., et al.: Zhongguo Yiyao Gongye Zazhi, 34, 425 (2003);<br></p>Formule :C23H19N3O4Couleur et forme :NeatMasse moléculaire :401.412,4-Difluorobenzoic Acid
CAS :Produit contrôlé<p>Applications 2,4-Difluorobenzoic Acid (cas# 1583-58-0) is a compound useful in organic synthesis.<br></p>Formule :C7H4F2O2Couleur et forme :NeatMasse moléculaire :158.105-(4-methylphenyl)imidazolidine-2,4-dione
CAS :Produit contrôlé<p>Applications 5-(4-methylphenyl)imidazolidine-2,4-dione (cas# 69489-37-8) is a useful research chemical.<br></p>Formule :C10H10N2O2Couleur et forme :NeatMasse moléculaire :190.20cis-Hydroxy Solifenacin N-Oxide(Mixture of Diastereomers)
Produit contrôlé<p>Applications Solifenacin (S676700) metabolite.<br></p>Formule :C23H26N2O4Couleur et forme :NeatMasse moléculaire :394.46Everolimus Isomer C (>60%, contains everolimus)
CAS :Produit contrôlé<p>Stability Unstable in solution, revert back to Everolimus<br>Applications Everolimus Isomer C is an isomer of Everolimus (E945400), a derivative of Rapamycin (R124000). Everolimus inhibits cytokine-mediated lymphocyte proliferation.<br>References Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001); Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001); Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002)<br></p>Formule :C53H83NO14Couleur et forme :NeatMasse moléculaire :958.226,8-Dioxo Apalutamide
CAS :Produit contrôlé<p>Applications 6,8-Dioxo Apalutamide is an impurity of Apalutamide (A726120). Apalutamide is a second-generation antiandrogen used in the treatment of prostate cancer.<br>References Li, Huifang, et al.: J. of Chem. Info. and Model., 53(1), 123-130 (2013);Joseph, James D., et al.: Cancer Disc., 3(9), 1020-1029 (2013)<br></p>Formule :C21H15F4N5O3Couleur et forme :NeatMasse moléculaire :461.38Dehydro Silodosin
CAS :Produit contrôlé<p>Applications Dehydro Silodosin is an impurity of Silodosin (S465000).<br>References Moriyama., et al.: Eur. J. Pharmacol., 331, 39 (1997), Zhu, J., et al.: Br. J. Pharmacol., 131, 546 (2000),<br></p>Formule :C25H30F3N3O4Couleur et forme :NeatMasse moléculaire :493.524-Hydroxy Tolvaptan (Mixture of Diastereomers)
CAS :Produit contrôlé<p>Applications Diastereomeric mixture of 4-Hydroxy Tolvaptan is an impurity of Tolvaptan (T536650), a selective, competitive arginine vasopressin V2 receptor antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).<br>References Ohtani, T., et al.: Heterocycles, 69, 333 (2006);<br></p>Formule :C26H25ClN2O4Couleur et forme :NeatMasse moléculaire :464.94Repirinast (>80%)
CAS :Produit contrôléFormule :C20H21NO5Degré de pureté :>80%Couleur et forme :NeatMasse moléculaire :355.38Valdecoxib Sulfonic Acid
CAS :Produit contrôlé<p>Applications Valdecoxib Sulfonic Acid is a metabolite of the potent and specific inhibitor of cyclooxygenase-2, Valdecoxib (V090000).<br>References Zhang, J.I. et al.: Drug Metab. Dispos., 31, 491 (2003); Yuan, J.J. et al.: Drug Metab. Dispos., 30, 1013 (2002);<br></p>Formule :C16H13NO4SCouleur et forme :White To Off-WhiteMasse moléculaire :315.34N-Nitroso Niraparib
Produit contrôléFormule :C19H19N5O2Couleur et forme :NeatMasse moléculaire :349.39β-Tetralone
CAS :Produit contrôlé<p>Applications β-Tetralone is the 2-keto derivative of Tetralin. β-Tetralone was initially reported to be a metabolite of Tetralin but was later found to be just an artifact in the metabolism process. β-Tetralone is known to be biological marker in fossil fuels.<br>References Elliott, T.H. et al.: Biochem. J., 108, 551 (1968); Armstrong, D. et al.: Microchem. J., 57, 149 (1997);<br></p>Formule :C10H10OCouleur et forme :NeatMasse moléculaire :146.19N-(4-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
CAS :Produit contrôlé<p>Applications Intermediate in the preparation of Imatinib impurities. It is a COVID19-related research product.<br></p>Formule :C16H15N5Couleur et forme :NeatMasse moléculaire :277.323-[2-[4-(6-Fluoro-2-benzoxazolyl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (Risperidone Impurity)
CAS :Produit contrôléFormule :C23H27FN4O2Couleur et forme :NeatMasse moléculaire :410.48N-Nitroso Amodiaquine
Produit contrôléFormule :C20H21ClN4O2Couleur et forme :NeatMasse moléculaire :384.859Denitro Tolcapone
CAS :Produit contrôléFormule :C14H12O3Couleur et forme :NeatMasse moléculaire :228.24N-Desethyl N-Methyl Rivastigmine
CAS :Produit contrôlé<p>Impurity Rivastigmine EP Impurity B<br>Applications N-Desethyl N-Methyl Rivastigmine (Rivastigmine EP Impurity B) is an impurity of Rivastigmine (R541000), a brain selective acetylcholinesterase inhibitor. Nootropic.<br>References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993),<br></p>Formule :C13H20N2O2Couleur et forme :NeatMasse moléculaire :236.32Paliperidone N-Oxide
CAS :Produit contrôlé<p>Impurity Paliperidone USP Related Compound D<br>Applications One of the major degradation product of Risperidone in bulk drug and pharmaceutical dosage forms. Paliperidone USP Related Compound D.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Leysen, J., et al.: J. Pharmacol. Exp. Ther., 247, 661 (1988), Huang, M., et al.: Pharm. Drug Dispos., 54, 257 (1993), Smyth, W., et al.: Anal. Bioanal. Chem., 378, 1305 (2004),<br></p>Formule :C23H27FN4O4Couleur et forme :NeatMasse moléculaire :442.48Fluphenazine β-D-Glucuronide
CAS :Produit contrôléFormule :C28H34F3N3O7SCouleur et forme :NeatMasse moléculaire :613.653,3-Diphenyl-oxiranecarboxylic Acid Methyl Ester
CAS :<p>Applications Ambrisentan intermediate.<br>References Amberg, W., et al.: J. Med. Chem., 42, 3026 (1999),<br></p>Formule :C16H14O3Couleur et forme :NeatMasse moléculaire :254.28Vortioxetine Lactose Adduct
Produit contrôlé<p>Stability Hygroscopic<br>Applications Vortioxetine Lactose Adduct, is an impurity of Vortioxetine (V766000), a multimodal serotonergic agent that inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT (1,2,3).<br>References Paunovic, A. et al.: ACS Chem. Biol., 12, 132 (2017);<br></p>Formule :C30H42N2O10SCouleur et forme :NeatMasse moléculaire :622.73Hydroxy Ebastine-d5
CAS :Produit contrôlé<p>Applications A labelled metabolite of Ebastine.<br>References Hashizume, T., et al.: Drug Metab. Dispos., 29, 798 (2001), Hashizume, T., et al.: J. Pharmacol. Exp. Ther., 300, 298 (2002), Matsumoto, S., et al.: Xenobiotica, 33, 615 (2003), Chaikin, P., et al.: Br. J. Clin. Pharmacol., 59, 346 (2005),<br></p>Formule :C32H34D5NO3Couleur et forme :NeatMasse moléculaire :490.694-Desisopropyl-4-ethyl Nateglinide
CAS :Produit contrôlé<p>Applications D-phenylanaline derivative and an analog Nateglinide (N379375) with similar hypoglycemic activity.<br>References Shinkai, H. et al.: J. Med. Chem., 32, 1436 (1989);<br></p>Formule :C18H25NO3Couleur et forme :NeatMasse moléculaire :303.40Levomepromazine-D3 Sulfoxide
CAS :Produit contrôléFormule :C19D3H21N2O2SCouleur et forme :NeatMasse moléculaire :347.49(S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one
CAS :Produit contrôlé<p>Applications (S)-4-(4-(5-(AMINOMETHYL)-2-OXOOXAZOLIDIN-3-YL)PHENYL)MORPHOLIN-3-ONE (cas# 446292-10-0) is a useful research chemical.<br></p>Formule :C14H17N3O4Couleur et forme :White To Off-WhiteMasse moléculaire :291.30(R)-(+)-α-Methylbenzylamine (>85%)
CAS :Produit contrôléFormule :C8H11NDegré de pureté :>85%Couleur et forme :NeatMasse moléculaire :121.18DL-threo-Droxidopa-d3 Hydrochloride Salt Hydrate
CAS :Produit contrôlé<p>Applications DL-threo-Droxidopa-d3 Hydrochloride Salt Hydrate is an isotope labeled compound of DL-threo-Droxidopa (D689950), a synthetic amino acid precursor of Norepinephrine. An Antiparkinson.<br>References Bartholini, J., et al.: J. Pharmacol. Exp. Ther ., 193, 523 (1975), Kato, T., et al.: Biochem. Pharmacol., 36, 3051 (1987), Kawabata, A., et al.: Br J. Pharmacol., 111, 503 (1994)<br></p>Formule :C9H8D3NO5•HCl•x(H2O)Couleur et forme :NeatMasse moléculaire :216.2136461802Raltegravir Potassium Salt
CAS :Produit contrôléFormule :C20H20FN6O5·KCouleur et forme :NeatMasse moléculaire :482.51Des(methylpiperazinyl-N-methyl) Imatinib Dimer Impurity
CAS :<p>Applications Des(methylpiperazinyl-N-methyl) Imatinib Dimer is an impurity of Imatinib (Gleevec) (G407000). Imatinib impurity E. It is a COVID19-related research product.<br></p>Formule :C52H48N12O2Couleur et forme :White To Off-WhiteMasse moléculaire :873.0210-Acetyloxy Oxcarbazepine
CAS :Produit contrôlé<p>Applications An intermediate in the preparation of Carbamazepine metabolites.<br>References Heckendorn, R., et al.: Helv. Chimica Acta, 70, 1955 (1987),<br></p>Formule :C17H14N2O4Couleur et forme :NeatMasse moléculaire :310.30Eltenac-13C,d3
CAS :Produit contrôlé<p>Applications Labelled Eltenac (E507000). A nonsteroidal anti-inflammatory drug.<br>References Allen, A., et al.: Gut, 21, 249 (1980), Tobin, T., et al.: J. Vet. Pharmacol. Therap., 9, 1 (1986),<br></p>Formule :CC11H7Cl2D2NO2SCouleur et forme :NeatMasse moléculaire :302.18Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro Dasatinib
CAS :Produit contrôlé<p>Applications Intermediate in the preparation of Dasatinib metabolite, used in the treatment of cancers and immune diseases. It is a COVID19-related research product.<br></p>Formule :C16H13Cl2N5O2SCouleur et forme :NeatMasse moléculaire :410.28rac Methyl Efavirenz (Mixture of Diastereomers)
CAS :Produit contrôlé<p>Applications Efavirenz (E425000) potential synthetic impurity and degradation product.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Phelan, P., et al.: J. Chromatogr. Sci., 19, 13 (1981), Mangia, A., et al.: Anal. Chim. Acta., 149, 349 (1983), Careri, M., et al.: J. Chromatogr., 647, 79 (1993), van Beek, T., et al.: Phytochem. Anal., 6, 1 (1995),<br></p>Formule :C15H11ClF3NO2Couleur et forme :NeatMasse moléculaire :329.70(Z)-4-(2,4-Difluorobenzoyl)piperidine Oxime
CAS :Produit contrôlé<p>Applications Intermediate in the preparation of Risperidone (R525000) and it’s derivatives.<br></p>Formule :C12H14F2N2OCouleur et forme :NeatMasse moléculaire :240.2492N-Desmethyl Prochlorperazine-d8 Dimaleate
CAS :Produit contrôléFormule :C27H22D8ClN3O8SCouleur et forme :NeatMasse moléculaire :600.112-Des(5-methyl-1,3,4-oxadiazole-2-carboxamide) 2-(2-(2-Acetylhydrazinyl)-2-oxoacetamide) Raltegravir
CAS :<p>Applications 2-Des(5-methyl-1,3,4-oxadiazole-2-carboxamide) 2-(2-(2-Acetylhydrazinyl)-2-oxoacetamide) Raltegravir is an impurity of a potent human immunodeficiency virus (HIV) integrase inhibitor. A novel anti-AIDS drug.<br>References Wade, K., et al.: J. Pharmacol. Biomed. Anal., 8, 401 (1990), Hazuda, D., et al.: Science, 287, 646 (2000), Williams, J., et al.: Drug Metab. Dispos., 32, 1201 (2004), Duckett, C., et al.: Xenobiotica, 36, 59 (2006), Miners, J., et al.: Biochem. Pharmacol., 71, 1531 (2006), Summa, V., et al.: J. Med. Chem., 49, 6646 (2006),<br></p>Formule :C20H23FN6O6Couleur et forme :Off-WhiteMasse moléculaire :462.435-Chloro-6-(piperidin-1-yl)pyrimidine-2,4-diamine
CAS :Produit contrôlé<p>Applications 5-Chloro-6-(piperidin-1-yl)pyrimidine-2,4-diamine is used for biological studies and has potential use in pharmaceutical compositions.<br>References Xiang, F.: Faming Zhuanli Shenqing. 39 pp. (2019)<br></p>Formule :C9H14ClN5Couleur et forme :NeatMasse moléculaire :227.69Olanzapine Lactam Impurity
CAS :<p>Impurity Olanzapine ketolactam impurity<br>Applications A degradation product of Olanzapine (LY170053) (O253750) in solid oral formulations.<br>References Chakrabarti, J., et al.: J.Med. Chem., 25, 1133 (1982), Chafetz, L., et al.: J. Pharm. Sci., 73, 1186 (1984), Hartauer, K., et al.: Pharm. Dev. Technol., 5, 303 (2000),<br></p>Formule :C17H20N4O2Couleur et forme :NeatMasse moléculaire :312.37Perphenazine-d8 Dihydrochloride Salt (1.0 mg/mL in Methanol)
CAS :Formule :C21H18D8ClN3OS·2HClCouleur et forme :ColourlessMasse moléculaire :484.93N-Nitroso-(1S,2R)-ephedrine
CAS :Produit contrôléFormule :C10H14N2O2Couleur et forme :NeatMasse moléculaire :194.23(4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-2-(4-methoxyphenyl)-4-(trifluoromethyl)-2H-3,1-benzoxazine(Mixture of 2 Diastereomers)
CAS :Produit contrôlé<p>Applications An impurity arising in the synthesis of Efavirenz (E425000).<br>References Chen, C., et al.: Enantiomer, 4, 599 (1999), Young, S.D., et al.: Antimicrob. Ag. Chemother., 39, 2602 (1995),<br></p>Formule :C21H17ClF3NO2Couleur et forme :NeatMasse moléculaire :407.81N-Methyl-o-phenylenediamine, Dihydrochloride
CAS :Produit contrôléFormule :C7H10N2·2ClHCouleur et forme :NeatMasse moléculaire :195.09Homopiperazine
CAS :Produit contrôlé<p>Applications Homopiperazine acts as a corrosion inhibitor for iron. It has also been used in the preparation of potent H3 receptor antagonists for use as treatments for neurodegenerative conditions such as Alzheimer’s disease.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Granese, S. et al.: Corrosion., 44, 322 (1988); Pippel, D. et al.: Org. Proc. Res. Devel., 15, 638 (2011);<br></p>Formule :C5H12N2Couleur et forme :NeatMasse moléculaire :100.16Ofloxacin N-Oxide Hydrochloride
CAS :Produit contrôléFormule :C18H20FN3O5·ClHCouleur et forme :Off-WhiteMasse moléculaire :413.83Carmustine-D8-Nitroso
Produit contrôléFormule :C5HD8Cl2N3O2Couleur et forme :NeatMasse moléculaire :193.101Despropylrotigotine
CAS :Produit contrôléFormule :C16H19NOSCouleur et forme :NeatMasse moléculaire :273.393-(Dibenzo[b,e]oxepin-11(6H)yl)-N,N-dimethylpropan-1-amine Hydrochloride
CAS :Produit contrôlé<p>Applications 3-(Dibenzo[b,e]oxepin-11(6H)yl)-N,N-dimethylpropan-1-amine Hydrochloride is an impurity of Doxepin (D550000), which is used clinically to treat anxiety and depression and is classified as an antidepressant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ribbentrop, A., et al.: Arzneim.-Forsch., 15, 863 (1965); Hobbs, D.C., et al.: Biochem. Pharmacol., 18, 1941 (1969); Pinder, R.M., et al.: Drugs, 13, 161 (1977); Shrivastava, R.K., et al.: Clin. Ther., 7, 181 (1985)<br></p>Formule :C19H23NO•(HCl)Couleur et forme :NeatMasse moléculaire :281.393646(4S3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl)amino][4-[(trimethylsilyl)oxy]phenyl]methyl]-1-oxo-5-[(trimethylsilyl)oxy]pentyl]-4-phenyl-2-oxazolidinone
CAS :Produit contrôlé<p>Applications (4S3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl)amino][4-[(trimethylsilyl)oxy]phenyl]methyl]-1-oxo-5-[(trimethylsilyl)oxy]pentyl]-4-phenyl-2-oxazolidinone is used in the synthesis of Ezetimibe (E975000), an antihyperlipoproteinemic; a cholesterol absorption inhibitor.<br>References Bankowski, K., et. al.: Przemysl Chemiczny, 91, 289 (2012); van Heek, M., at al.: J. Pharmacol. Exp. Ther., 283, 157 (1997); van Heek, M., at al.: Brit. J. Pharmacol., 129, 1748 (2000)<br></p>Formule :C39H46F2N2O5Si2Couleur et forme :NeatMasse moléculaire :716.961[3-(9H-Carbazol-4-yloxy)-2-hydroxy]propyl Carvedilol
CAS :Produit contrôléFormule :C39H39N3O6Couleur et forme :NeatMasse moléculaire :645.74Olanzapine-d3 (1 mg/ml in Acetonitrile)
CAS :Produit contrôléFormule :C172H3H17N4SCouleur et forme :ColourlessMasse moléculaire :315.452-(4-(Methylsulfonamido)phenyl)acetic Acid
CAS :Produit contrôlé<p>Applications 2-(4-(Methylsulfonamido)phenyl)acetic Acid acts as a reagent for resiniferatoxin analogs preparation as metabolically stable TRPV1 agonists and potential analgesics. Preparation and structure-activity relationships of 2,6-diaryl-4-(phenacylamino)pyrimidines as selective adenosine A2A antagonists.<br>References Choi, H., et al.: Bioorg. Med. Chem. , 17, 690 (2009); Moorjani, M., et al.: Bioorg. Med. Chem. Lett., 18, 1269 (2008)<br></p>Formule :C9H11NO4SCouleur et forme :NeatMasse moléculaire :229.256-Amino-1-methyl-5-nitrosouracil
CAS :Produit contrôlé<p>Stability Light and temperature sensitive<br>Applications 6-Amino-1-methyl-5-nitrosouracil is known to exhibit anitmicrobial activity and form complexation with platinum (II).<br>References Gaballa, A.S., et al.: Molec. Biomolec. Spectro. 75A, 146 (2010);<br></p>Formule :C5H6N4O3Couleur et forme :NeatMasse moléculaire :170.134-Hydroxy Phenylbutazone
CAS :<p>Applications Impurity in the production of Phenylbutazone (P319570)<br>References Fricoteaux, R., et al.: J. Pharm. Biomed. Anal., 7, 1585 (1989), Segrestaa, J., et al.: Chem. Pharm. Bull., 50, 744 (2002),<br></p>Formule :C19H20N2O3Couleur et forme :White To Off-WhiteMasse moléculaire :324.37N-Triphenylmethyl-5-[4'-methylbiphenyl-2-yl]tetrazole
CAS :Produit contrôlé<p>Applications An intermediate in the preparation of Candesartan. Also used in the synthesis of novel biphenyltetrazole derivatives.<br>References Chao, S. et al.: J. Chin. Chem. Soc., 52, 539 (235);<br></p>Formule :C33H26N4Couleur et forme :NeatMasse moléculaire :478.59Hydroxy Saxagliptin
CAS :Produit contrôlé<p>Applications Hydroxy Saxagliptin is a metabolite of Saxagliptin (S143500).<br>References Patel, C. et al.: J. Clinic. Pharmacol., 50, 1211 (2010); Feng, J., et al.: J. Med. Chem., 50, 2297 (2007),:Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008);<br></p>Formule :C18H25N3O3Couleur et forme :NeatMasse moléculaire :331.41rac Methotrimeprazine Sulfoxide
CAS :Produit contrôlé<p>Applications A metabolite of Methotrimeprazine (M260785).<br>References Haddad, P., et al.: Drugs, 62, 1649 (2002),<br></p>Formule :C19H24N2O2SCouleur et forme :NeatMasse moléculaire :344.47rac trans-2-Phenylcyclopropylamine Hydrochloride
CAS :Produit contrôlé<p>Applications Non-selective MAO-A/B inhibitor.<br>References Stout, S.C., et al.: J. Pharmacol. Exp. Ther., 300, 1085 (2002),<br></p>Formule :C9H11N·ClHCouleur et forme :NeatMasse moléculaire :169.65(3S)-1-[2-(3-Ethenyl-4-hydroxyphenyl)ethyl]-α,α-diphenyl-3-pyrrolidineacetamide
CAS :Produit contrôléFormule :C28H30N2O2Couleur et forme :NeatMasse moléculaire :426.553-(Trifluoromethoxy)aniline
CAS :Produit contrôlé<p>Applications 3-(Trifluoromethoxy)aniline is reactant in the synthesis of pyrazolone-quinazolone hybrids as human hydroxyphenylpyruvate dioxygenase inhibitors which is a potential treatment for type I tyrosinemia.<br>References Xu, Y., et. al.: Bioorg. Med. Chem., 22, 5194 (2014)<br></p>Formule :C7H6F3NOCouleur et forme :NeatMasse moléculaire :177.12Methyl 4-Amino-3-methylbenzoate
CAS :Produit contrôlé<p>Applications Methyl 4-Amino-3-methylbenzoate is used in the synthesis of neuroprotective hydrazides used in the treatment of Alzheimer’s. It is also used in the research and development of diphenylamine-based retinoids.<br>References Chiruta, C. et al.: Bioorg. Med. Chem. Lett., 21, 2733 (2013); Ohta, K. et al.: Bioorg. Med. Chem. Lett., 23, 81 (2013);<br></p>Formule :C9H11NO2Couleur et forme :NeatMasse moléculaire :165.192-Methylisoindole-1,3-dione
CAS :Produit contrôlé<p>Applications Photoreduction of N-methylphthalimide (NMP) with 2,3-dimethyl-2-butene h and the selective electroreduction of N-methylphthalimide to 3-hydroxy-2-methyl-isoindolin-1-one have been studied.<br>References Mazzocchi, P., et al.: J. Am. Chem. Soc., 106, 7567 (1984); Villagran, C., et al.: Ultrasonics Sonochemistry, 12, 423 (2005)<br></p>Formule :C9H7NO2Couleur et forme :NeatMasse moléculaire :161.16N-Nitrosopendimethalin-d4
Produit contrôléFormule :C13H14D4N4O5Couleur et forme :NeatMasse moléculaire :337.367Moxonidine
CAS :Produit contrôlé<p>Applications Moxonidine is an antihypertensive agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rayment, S., et al.: Brit. J. Pharmacol., 160, 1727 (2010), Taksande, B., et al.: Eur. J. Pharmacol., 637, 89 (2010), Nasr, M., et al.: Vas. Pharmacol., 53, 53 (2010),<br></p>Formule :C9H12ClN5OCouleur et forme :NeatMasse moléculaire :241.682-epi-Darunavir
CAS :<p>Applications 2-epi-Darunavir is a stereoisomer to Darunavir (D193500), a second generation HIV-1-protease inhibitor; structurally similar to amprenavir. Antiviral. It is a COVID19-related research product.<br>References Rao, R.N., et. al.: J. Sep. Sci., 35, 2671 (2012); Koh, Y., et al.: Antimicrob. Agents Chemother., 47, 3123 (2003); Arasteh, K., et al.: AIDS, 19, 943 (2005); Surleraux, D.L.N.G., et al.: J. Med. Chem., 48, 1813 (2005)<br></p>Formule :C27H37N3O7SCouleur et forme :NeatMasse moléculaire :547.66
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