Dérivés de Quinazoline et de Quinoléine
Les quinazolines et les quinoléines sont des composés hétérocycliques azotés à structure aromatique qui jouent un rôle clé dans la synthèse de médicaments à activité anticancéreuse, antimicrobienne et anti-inflammatoire. Leurs dérivés présentent des modifications structurelles qui optimisent leur biodisponibilité et leur sélectivité, permettant ainsi le développement de nouveaux principes actifs pour diverses applications thérapeutiques. Ces composés sont utilisés dans la fabrication d’API destinés au traitement du cancer, des infections, des maladies neurodégénératives et cardiovasculaires. De plus, les dérivés de quinazoline et de quinoléine sont essentiels dans la recherche d’inhibiteurs enzymatiques et dans la conception de molécules bioactives innovantes.
Chez CymitQuimica, nous proposons des dérivés de quinazoline et de quinoléine de haute pureté pour des applications en synthèse chimique, développement pharmaceutique et biotechnologie.
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rac-3-Deacetyl-3-butanoyl acebutolol hydrochloride
CAS :<p>3-Deacetyl-3-butanoyl acebutolol hydrochloride is a racemic mixture of two enantiomers, (+)-(S)-3-Deacetyl-3-butanoyl acebutolol and (-)-(R)-3-Deacetyl-3-butanoyl acebutolol. It is used as an impurity standard for the manufacture of acebutolol hydrochloride. The substance has a purity of at least 99% by HPLC. 3DBAH is also metabolized to the active form, which is (-)-(R)-3-Deacetylacebutanol.</p>Formule :C20H33ClN2O4Degré de pureté :Min. 95%Masse moléculaire :400.94 g/molN-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine formamide hydrochloride
CAS :<p>N-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine formamide hydrochloride is an impurity in the synthesis of N-(4-amino-6,7-dimethoxyquinazol-2-yl)-N'-methylpropylenediamine formamide hydrochloride. It is a white solid that can be used as an analytical reference standard for HPLC. It has been detected in the urine of people taking this drug and can be used to identify the presence of this drug in urine samples.</p>Formule :C14H17N5O2·HClDegré de pureté :Min. 95%Masse moléculaire :323.78 g/molChlorhexidine dihydrochloride impurity B
CAS :<p>Chlorhexidine dihydrochloride impurity B is an impurity found in chlorhexidine dihydrochloride, a drug that is used as an antiseptic and disinfectant. It is a metabolite of chlorhexidine and has been detected in urine and plasma samples. This impurity has no known pharmacological activity. The purity of this compound is not less than 99%.</p>Formule :C16H28Cl3N9ODegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :468.81 g/molLabetalol EP impurity D
CAS :<p>Labetalol EP impurity D is a metabolite of labetalol that is used as an impurity standard for HPLC. This impurity has been identified in the drug product and also in the drug development process. Labetalol EP impurity D is one of many metabolites that can be formed by cytochrome P450 enzymes. Labetalol EP impurity D is a natural metabolite of labetalol, which can be found in the urine of humans and other mammals. It is also present in various plants and fungi, including mushrooms, lichens, yeast, and barley. Synthetic labetalol EP impurity D can also be produced by various chemical reactions.</p>Formule :C9H12N2O3Degré de pureté :Min. 95%Masse moléculaire :196.2 g/molN-(Aminosulphonyl)-2-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methylsulphinyl]propanimidamide
CAS :<p>N-(Aminosulphonyl)-2-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methylsulphinyl]propanimidamide (NTSX) is an analytical standard and a metabolite of the drug product N-(aminosulphonyl)-2-[[[2-[(aminothiazolyl)methyl]sulfinyl]propanimidamide (NTST). The CAS number is 109467-06-3. NTSX is a white to off-white crystalline powder that is soluble in water and has a molecular weight of 296.37. It has been shown to be active against ampicillin resistant strains of Staphylococcus aureus, but not against methicillin resistant strains. NTSX can be synthesized from the drug NTST or obtained as an impurity from the synthesis of NTST.</p>Formule :C8H15N7O3S3·C4H4O4Degré de pureté :Min. 95%Masse moléculaire :469.52 g/mol3,4-Dimethoxy-N,N-dimethyl-benzeneethanamine hydrochloride
CAS :Produit contrôlé<p>3,4-Dimethoxy-N,N-dimethyl-benzeneethanamine hydrochloride is a drug product that is used as an analytical standard. This drug development chemical is not found in nature and has been synthesized in the laboratory. The chemical's structure closely resembles that of amphetamine and methamphetamine. 3,4-Dimethoxy-N,N-dimethyl-benzeneethanamine hydrochloride is used to develop analytical methods for determining impurities in APIs such as 3,4-dimethoxyamphetamine (DMA). It is also used to help identify metabolites of amphetamines. 3,4-Dimethoxy-N,N-dimethyl-benzeneethanamine hydrochloride has been shown to have a half life of approximately 12 hours and is excreted through the urine.</p>Formule :C12H19NO2·HClDegré de pureté :Min. 95%Masse moléculaire :245.75 g/molFluvoxketone
CAS :<p>Fluvoxketone is a drug that belongs to the class of selective non-steroidal anti-inflammatory drugs. It is a mixture of stereoisomers, with a ratio of 1:1, which have different pharmacological properties. Fluvoxketone has an average elution time of 18 minutes and can be detected in the sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE) profile at around 10 minutes. This drug was selected as the optimum drug for this study by optimisation of its solubility, selectivity, and stability.</p>Formule :C13H15F3O2Degré de pureté :Min. 95%Masse moléculaire :260.25 g/mol[5-[(Dimethylamino)methyl]furan-2-yl]methanol
CAS :<p>Dimethylaminoethyl methacrylate is a chemical compound that belongs to the group of dimeric monomers. It is an activated form of methacrylates, which are compounds containing the -C(O)OC-CH2-CH2-O-CO-R functional group. The activated form is prepared by the reaction of a primary amine with acetic acid and acrylic acid. Dimethylaminoethyl methacrylate has been used as a carbohydrate adduct to create glycoconjugates and it has been shown to have anti-mutagenic properties. This product can be found in high concentrations in China.</p>Formule :C8H13NO2Degré de pureté :Min. 95%Masse moléculaire :155.19 g/mol2-[3-[4-(3-Chloro-4-ethylphenyl)-1-piperazinyl]propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one
CAS :<p>2-[3-[4-(3-Chloro-4-ethylphenyl)-1-piperazinyl]propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one is a research and development impurity standard. Impurities are the substances that are not intentionally added to the drug product but can be generated from the synthesis process or from the raw materials. This substance has been used as a synthetic intermediate in the production of other drugs and as an analytical reference for HPLC analysis. It is used to help develop new drugs by providing data about metabolites and possible toxic effects on humans.</p>Degré de pureté :Min. 95%N-(3-hydroxytricyclo[3.3.1.1]dec-1-yl)glycyl-L-prolinamide
CAS :<p>N-(3-hydroxytricyclo[3.3.1.1]dec-1-yl)glycyl-L-prolinamide is a metabolite that is formed when the drug product, ticagrelor, undergoes metabolism in the liver. Ticagrelor is a prodrug that requires conversion to its active form, which is N-(3-hydroxytricyclo[3.3.1.1]dec-1-yl)glycyl-L-prolinamide, before it can be used as a platelet inhibitor and antiplatelet agent for the prevention of thrombotic events such as heart attack and stroke. It has been shown to have an excellent stability profile and high purity when produced by HPLC or synthesized using the latest methodology under GMP conditions.</p>Degré de pureté :Min. 95%Risperidone E-oxime impurity
CAS :<p>Risperidone E-oxime impurity is a drug product that has been studied for its metabolism in humans, animals and plants. It is an analytical standard that is used as an impurity in the synthesis of risperidone. Risperidone E-oxime impurity is also a synthetic compound with CAS No. 691007-09-7. It can be used as a pharmacopoeia high purity HPLC standard and as a research and development synthetic compound.</p>Formule :C23H28F2N4O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :430.49 g/molEthyl 2-methoxy-5-sulfamoylbenzoate
CAS :<p>Ethyl 2-methoxy-5-sulfamoylbenzoate is a research and development impurity standard. It is a white to off-white crystalline solid that is soluble in water. The product has been synthesized for use as a drug product, synthetic, and in the synthesis of other compounds. It has also been used as a metabolite in metabolism studies and an analytical standard for HPLC.</p>Formule :C10H13NO5SDegré de pureté :Min. 95%Masse moléculaire :259.28 g/molChlorhexidine diacetate EP Impurity O
CAS :<p>Chlorhexidine diacetate EP Impurity O is an analytical reference material that is used as a pharmaceutical impurity. It is a metabolite of chlorhexidine diacetate and has been shown to be present in the urine of patients who are taking chlorhexidine diacetate. Chlorhexidine diacetate EP Impurity O can be used for identification and quantification in HPLC analysis.</p>Formule :C22H30Cl2N10Degré de pureté :Min. 95%Masse moléculaire :505.45 g/mol[4-(4-Amino-6-hydroxy-7-methoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)-methanone
CAS :<p>4-(4-Amino-6-hydroxy-7-methoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)-methanone (CAS No. 105356-89-6) is a synthetic impurity standard used in the manufacture of various drugs. Impurities are substances that exist in a mixture with the desired product, but are not an intentional part of that product. Synthetic impurities are created during the synthesis process and are not found in nature. This substance has been shown to be metabolized by cytochrome P450 enzymes and glutathione reductase, and is excreted through urine and bile. It also binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.</p>Formule :C18H23N5O4Degré de pureté :Min. 95%Masse moléculaire :373.41 g/mol2-Ethoxy-1-[[2'-[1-(trityl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-4-carboxylic acid methyl ester
CAS :<p>2-Ethoxy-1-[2'-[1-(trityl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-4-carboxylic acid methyl ester is an impurity in the drug product, which is a synthetic drug for research and development. The impurity standard for 2-ethoxy-1-[2'-[1-(trityl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H benzimidazole 4 carboxylic acid methyl ester is available in quantities of 10g. The CAS number for the impurity is 150058-29-0. This compound has an API purity of 99.9%. Impurities are not expected to be present at greater than 1% by weight.</p>Formule :C44H36N6O3Degré de pureté :Min. 95%Masse moléculaire :696.8 g/molTrazodone Impurity A
CAS :<p>Trazodone Impurity A is a drug product that is an impurity standard for Trazodone. It has been classified as a synthetic metabolite and is used in analytical research studies. Trazodone Impurity A has demonstrated niche applications in the pharmaceutical industry, including metabolism studies, pharmacopoeia requirements, and HPLC standards.</p>Formule :C19H22ClN5ODegré de pureté :Min. 95%Masse moléculaire :371.86 g/molLosartan isomer impurity, potassium salt
CAS :Produit contrôlé<p>Losartan is an angiotensin II receptor antagonist. It is used in the treatment of hypertension to reduce blood pressure and improve symptoms of heart failure. Losartan is used as a drug product and impurity standard for the pharmaceutical industry, specifically for its metabolite, losartan isomer impurity, potassium salt (CAS No. 860644-28-6). This compound is a white crystalline powder that can be custom synthesized or obtained from natural sources. High purity Losartan Isomer Impurity, Potassium Salt (CAS No. 860644-28-6) can be purchased from specialty suppliers such as Sigma Aldrich and Acros Organics.</p>Formule :C22H22ClKN6ODegré de pureté :Min. 95%Masse moléculaire :461 g/molCitalopram N-oxide hydrochloride
CAS :<p>Citalopram N-oxide hydrochloride is the n-oxide form of the antidepressant drug citalopram. It is a metabolite of citalopram that has been shown to have higher activity than the parent compound. The presence of citalopram N-oxide was detected in plasma samples using liquid chromatography with a wavelength of 220 nm and diethylamine as an eluent. Citalopram N-oxide hydrochloride has been shown to be pharmacologically active in animal studies, but its effects are not well understood.</p>Formule :C20H22FN2O2ClDegré de pureté :Min. 95%Couleur et forme :SolidMasse moléculaire :376.13538Montelukast Bis-sulfide(mixture of diastereomers)
CAS :<p>Montelukast Bis-sulfide is a drug product that is custom synthesized with high purity. It has been studied for its metabolism, analytical properties, and natural sources. The metabolite of montelukast bis-sulfide has been extensively researched for pharmacopoeia as well as for drug development. Montelukast bis-sulfide is a synthetic compound that is not found in nature, but it has niche applications in research and development. CAS No.: 1242260-05-4</p>Formule :C41H46ClNO5S2Degré de pureté :Min. 95%Masse moléculaire :732.39 g/mol(3-endo)-9-methyl-9-azabicyclo[3.3.1]nonan-3-amine
CAS :<p>Granisetron is a drug that belongs to the group of serotonin receptor antagonists. It is used as an antiemetic, mainly in the prevention and treatment of nausea and vomiting caused by cancer chemotherapy and surgery. This drug has been shown to be effective in controlling nausea and vomiting, even when given after chemotherapy or surgical procedures. Granisetron hydrochloride was synthesized in 1988 by chemists at Hoffmann-La Roche. The synthesis was patented in 1990. Potential impurities are not listed on the USP or EP pharmacopeia, but these impurities have been detected during synthesis.</p>Formule :C9H18N2Degré de pureté :Min. 95%Masse moléculaire :154.25 g/molTrazodone Hydrochloride BP Impurity A
CAS :<p>Trazodone Hydrochloride BP Impurity A is an unproven impurity of Trazodone. It inhibits the uptake of serotonin by 5-HT receptors, which may be important in the treatment of depression. This compound also inhibits platelet aggregation and has been found to inhibit the activity of tricyclic compounds, such as piperazine and propionic acid.</p>Formule :C19H22CIN5O2Degré de pureté :Min. 95%Masse moléculaire :491.33 g/molrac-N-Desbutyroyl acebutolol
CAS :<p>rac-N-Desbutyroyl acebutolol is a prodrug that is metabolized to the active form, acebutolol. The metabolism of rac-N-desbutyroyl acebutolol is mediated through cytochrome P450 (CYP) enzymes, specifically CYP2D6. Rac-N-desbutyroyl acebutolol has been shown to inhibit the growth of bacteria in vitro and in vivo. It has also been shown to have therapeutic effects on diabetic patients with high levels of fatty acids in their blood. Rac-N-desbutyroyl acebutolol has also been found to be effective for the treatment of patients with polycarboxylic acid exposure and dna replication diseases.</p>Formule :C14H22N2O3Degré de pureté :Min. 95%Masse moléculaire :266.34 g/molKetoconazole Impurity A
CAS :<p>Ketoconazole Impurity A is a synthetic impurity of Ketoconazole, which is used as an anti-fungal agent. Ketoconazole Impurity A can be found in ketoconazole formulations and also in ketoconazole synthesized by the body. Ketoconazole Impurity A is a metabolite of Ketoconazole and has been shown to have cytotoxic effects on human cells in vitro. Ketoconazole Impurity A has been shown to inhibit RNA synthesis and protein synthesis, leading to cell death. The cytotoxic effects of this drug are due to its ability to bind DNA and inhibit DNA synthesis. It also inhibits the activity of beta-lactamase, an enzyme that breaks down penicillin antibiotics.</p>Formule :C26H26Cl2N4O4Degré de pureté :Min. 95%Masse moléculaire :529.41 g/mol2-Deschloro aripiprazole
CAS :<p>2-Deschloro aripiprazole is a drug that belongs to the class of antipsychotics. It is an atypical antipsychotic with a high affinity for human albumin and α1-acid glycoprotein, which are plasma proteins. 2-Deschloro aripiprazole has been shown to interact with human albumin and α1-acid glycoprotein in vitro, and it has been suggested that this interaction may be responsible for its pharmacological effects. 2-Deschloro aripiprazole has also been shown to bind to the dopamine D2 receptor, which is thought to be responsible for its therapeutic effects as an antipsychotic. The molecular interactions between 2-deschloro aripiprazole and human albumin have been studied using isothermal titration calorimetry (ITC) and molecular docking studies. These studies have helped us understand how 2-deschloro aripiprazole binds to human album</p>Formule :C23H28ClN3O2Degré de pureté :Min. 95%Masse moléculaire :413.94 g/mol(R,R)-Solifenacin succinate
CAS :<p>(R,R)-Solifenacin succinate is a pharmaceutical agent that acts as an antimuscarinic drug. It has been shown to be effective in wastewater treatment, where it was found to reduce the amount of solifenacin and optimised organic chemicals in the water. This drug has also been shown to have antagonist properties against the muscarinic receptor M3.</p>Formule :C23H26N2O2•C4H6O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :480.55 g/molSolifenacin EP impurity F succinate
CAS :<p>Solifenacin is an anti-cholinergic drug that has been shown to have a potent antagonistic effect on muscarinic receptors. It is used in the treatment of overactive bladder, urinary incontinence, and irritable bowel syndrome. Solifenacin succinate is a metabolite of solifenacin and it has been found to be an antagonist of M3 muscarinic receptors. The presence of solifenacin and its metabolites in wastewater can interfere with treatment processes by inhibiting the removal of other organic chemicals such as tamsulosin hydrochloride. Optimisation studies for solifenacin production have shown that famotidine can be used as a process aid to reduce solifenacin impurities. Famotidine is also an antagonist of M3 muscarinic receptors and can be used to remove solifenacin from wastewater. Analytes detected in wastewater samples include solifenacin, famot</p>Formule :C27H32N2O6Degré de pureté :Min. 95%Masse moléculaire :480.55 g/mol2-Methoxyethyl-3-aminocrotonate
CAS :<p>2-Methoxyethyl-3-aminocrotonate is an impurity of a drug product. It is an analytical standard that is used to quantify the metabolite in pharmaceutical preparations. 2-Methoxyethyl-3-aminocrotonate is a natural metabolite, which can be found in human urine. This compound has been shown to be a potent inhibitor of both bacterial and mammalian cell topoisomerase II and IV, but not mammalian cell topoisomerase I. It also inhibits protein synthesis by binding to the ribosomal 50S subunit. In addition, it has been shown to inhibit the growth of certain bacteria such as clostridium perfringens and Mycobacterium tuberculosis.</p>Formule :C7H13NO3Degré de pureté :Min. 95%Masse moléculaire :159.18 g/mol(2R)-2-(3,4-Dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-isopropylpentanenitrile hydrochloride
CAS :<p>(2R)-2-(3,4-Dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-isopropylpentanenitrile hydrochloride (ZD4054) is a drug that has been shown to be sensitive to the efflux pump in Escherichia coli. It is also able to inhibit multidrug resistance in nematodes and cross-resistance in humans. ZD4054 inhibits multidrug resistance by inhibiting the efflux of drugs from cells. This prevents the development of resistance to antibiotics and other drugs. The mechanism of action for this drug is unknown, but it may affect chloride channels that are found on the cell membrane. ZD4054 has also been shown to be effective against C.elegans and Drosophila melanogaster, two species commonly used for research purposes.</p>Formule :C27H39ClN2O4Degré de pureté :Min. 95%Masse moléculaire :491.06 g/molRisperidone N-oxide
CAS :<p>Risperidone N-oxide is a prodrug of risperidone. It is prepared by reacting risperidone with methanol and hydrogen peroxide in the presence of piperidine, followed by purification using preparative high-performance liquid chromatography. Risperidone N-oxide is a crystalline solid with a melting point of about 190 °C. Risperidone N-oxide has been shown to have antiemetic properties, which may be due to its ability to block dopamine receptors in the brain. The drug also shows some antipsychotic activity, and it has a constant therapeutic effect against schizophrenia. The major impurities found in risperidone N-oxide are hydroxylamine and piperidine.</p>Formule :C23H27FN4O3Degré de pureté :Min. 95%Masse moléculaire :426.48 g/mola-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-propyl-benzeneacetonitrile
CAS :<p>a-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-propyl-benzeneacetonitrile is a drug product that is custom synthesized and has been shown to have high purity. It is also used in analytical studies, metabolism studies, and natural drug development. This compound can also be found as an impurity standard for HPLC or as an API impurity.</p>Formule :C27H38N2O4Degré de pureté :Min. 95%Masse moléculaire :454.6 g/mola,a,a',a'-Tetramethyl-5-bromomethyl-1,3-benzenediacetonitrile
CAS :<p>Tetramethyl-5-bromomethyl-1,3-benzenediacetonitrile (TMBDAC) is an impurity standard and a metabolite of the drug product. It is an analytical standard for HPLC. Tetramethyl-5-bromomethyl-1,3-benzenediacetonitrile is a high purity research and development chemical that can be custom synthesized to meet specific needs. This synthetic compound has shown potential as a niche metabolite in metabolism studies. CAS No. 120511-84-4.</p>Formule :C15H17BrN2Degré de pureté :Min. 95%Masse moléculaire :305.21 g/molAlverine EP Impurity E
CAS :<p>Alverine EP Impurity E is a nitrogen containing compound with the molecular formula C9H10N. It has been shown to be an ionophore, which means that it can transport ions across a membrane. Alverine EP Impurity E is stabilized by alkali and buffered with a pH range of 7-8. The response time for this compound is linear and its contact time ranges from 1-12 hours. This impurity has a phenyl group and a ph range of 6-7. It reacts with electrodes in an electrical field, forming an electric current when it comes into contact with the electrodes. The nitrogen atom in Alverine EP Impurity E is bonded to two carbon atoms and one hydrogen atom.</p>Formule :C27H33NDegré de pureté :Min. 95%Masse moléculaire :371.56 g/mol4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide
CAS :<p>4-Methyl-3-[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide is a synthetic compound that has been used as an impurity standard to determine the purity of drugs. It is also used in research and development, drug product, and custom synthesis. 4-Methyl-3-[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide has a CAS number of 851137-91-2 and is on the list of pharmacopoeias. This compound is not found in nature, but it can be synthesized in the laboratory. Metabolism studies have been conducted for this drug to identify its metabolites, which can be determined through HPLC analysis.</p>Formule :C17H15N5ODegré de pureté :Min. 95%Masse moléculaire :305.33 g/molAmido methyl meloxicam
CAS :<p>Amido methyl meloxicam is a synthetic nonsteroidal anti-inflammatory drug. It is used to relieve inflammation and pain. Amido methyl meloxicam is chemically similar to the naturally occurring substance, meclofenamic acid, but it does not have the same side effects.<br>Amido methyl meloxicam is metabolized in the liver by CYP3A4/5 and then excreted by the kidneys.</p>Formule :C15H15N3O4S2Degré de pureté :Min. 95%Masse moléculaire :365.43 g/mol(1-Ethyl-1-methylpropyl)benzene
CAS :<p>(1-Ethyl-1-methylpropyl)benzene is an impurity of some drugs. It is a metabolite of the drug, and can be found in urine or blood samples as a result of its excretion from the body. (1-Ethyl-1-methylpropyl)benzene is used as an analytical standard for HPLC analysis. This chemical is not on the USP list of impurities, but it is listed on the pharmacopoeia. The CAS number for (1-Ethyl-1-methylpropyl)benzene is 1985-97-3.</p>Formule :C12H18Degré de pureté :Min. 95%Masse moléculaire :162.27 g/mol(aR)-a-Methyl-N-[3-[4-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine
CAS :<p>(aR)-a-Methyl-N-[3-[4-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine is a synthetic drug product that is used in research and development. It has been shown to have an analytical purity of 99.8%.</p>Formule :C22H22F3NDegré de pureté :Min. 95%Masse moléculaire :357.41 g/molPantoprazole sulfone N-oxide
CAS :<p>Pantoprazole sulfone N-oxide is a prodrug that is converted to the active form pantoprazole in the stomach where it inhibits gastric acid secretion. Pantoprazole sulfone N-oxide has been shown to be genotoxic, and can cause polyvinyl chloride to degrade when stored together. Reconstituted solution of this drug should be used within 24 hours after reconstitution, as the chemical stability of this drug decreases rapidly. Validation studies have been conducted on different analytical methods for determining pantoprazole concentrations in reconstituted solutions, and these methods have been harmonized with those published by the United States Pharmacopeia (USP). The pump inhibitor activity of pantoprazole sulfone N-oxide has been demonstrated in dogs, and it is also useful for treating acid reflux disease in humans. Pantoprazole sulfone N-oxide is unstable at high temperatures (>25°C), so should not be refrigerated or</p>Formule :C16H15F2N3O6SDegré de pureté :Min. 95%Masse moléculaire :415.37 g/mol3,4-Bis(2-methoxyethoxy)benzoic acid ethyl ester
CAS :<p>3,4-Bis(2-methoxyethoxy)benzoic acid ethyl ester is a compound that has been shown to have bactericidal activity against Gram-positive bacteria. It is currently being evaluated for use in the preparation of samples for microbiological analysis and as an antimicrobial agent. 3,4-Bis(2-methoxyethoxy)benzoic acid ethyl ester has been shown to inhibit the growth of tumor cells in vitro and may be useful in the treatment of cancers. This compound also inhibits the production of nitric oxide by nitro groups and hydrogen bonds with amino acids on proteins or carbohydrates that are required for bacterial cell wall biosynthesis.</p>Formule :C15H22O6Degré de pureté :Min. 95%Masse moléculaire :298.33 g/mol1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-b enzimidazole
CAS :<p>1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-b enzimidazole is an impurity of a drug product. It is a metabolite that has been shown to be present in human plasma and urine. This compound is synthetically produced and is not found in nature. It has been shown to have niche applications in both analytical chemistry and pharmacopoeia.</p>Formule :C25H22F6N4O3SDegré de pureté :Min. 95%Masse moléculaire :572.52 g/mol[6-Hydroxy-2-(4-hydroxyphenyl)-benzo[b]thien-7-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone
CAS :<p>6-Hydroxy-2-(4-hydroxyphenyl)-benzo[b]thien-7-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone is a synthetic impurity standard that is used as a reference material in the analytical, natural and drug development, and metabolite studies. 6-Hydroxy-2-(4-hydroxyphenyl)-benzo[b]thien-7-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone has a molecular weight of 390.27 and chemical formula C26H28N2O3S. It is also referred to by its CAS number 1391054-73-1.6</p>Formule :C28H27NO4SDegré de pureté :Min. 95%Masse moléculaire :473.58 g/mol3,4-Dihydro-7-(3’carboxy)propoxy-2(1H)-quinolinone
CAS :Produit contrôlé<p>Please enquire for more information about 3,4-Dihydro-7-(3’carboxy)propoxy-2(1H)-quinolinone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C13H15NO4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :249.26 g/mol3’-Destrifluoromethyl 2’-trifluoromethyl cinacalcet
CAS :<p>3' - Destrifluoromethyl 2' - trifluoromethyl cinacalcet is a metabolite of cinacalcet, which is a drug used for the treatment of secondary hyperparathyroidism. It is an impurity in the drug product and can be identified by HPLC.</p>Formule :C22H22F3NDegré de pureté :Min. 95%Masse moléculaire :357.41 g/mol3-[2-[4-(2,4-Difluorobenzoyl)piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one
CAS :<p>Roflumilast is a drug used to treat chronic obstructive pulmonary disease. It is also used to treat inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis. Roflumilast inhibits the enzyme cytochrome P450 in the liver, which is responsible for metabolizing certain drugs and other substances. This inhibition reduces the metabolism of these substances, leading to increased levels of these substances in the body. This can lead to side effects such as nausea, vomiting, dizziness, headache, and itching. Roflumilast also has an anti-inflammatory effect on the intestines by regulating the production of inflammatory cytokines and inhibiting the activity of pro-inflammatory enzymes.</p>Formule :C23H27F2N3O2Degré de pureté :Min. 95%Masse moléculaire :415.48 g/mol(S)-3-(Dimethylamino)-1-(2-thienyl)propan-1-ol
CAS :<p>(S)-3-(Dimethylamino)-1-(2-thienyl)propan-1-ol is a polymerase chain reaction (PCR) reagent that is used as a building block for the synthesis of five membered ring lactams and dihedral polymers. This compound is synthesized by chemoenzymatic coupling of propanamine with trifluoroacetic acid in the presence of methyl groups, followed by catalytic hydrogenation to yield the desired product. The asymmetric synthesis of this compound was achieved through chiral resolution using NMR spectroscopy.</p>Formule :C9H15NOSDegré de pureté :Min. 95%Masse moléculaire :185.29 g/molValdecoxib 3'-sulfonamide
CAS :<p>Valdecoxib 3'-sulfonamide is a synthetic, non-naturally occurring drug product that has been custom synthesized for the purposes of research and development. It is not a natural API nor is it an impurity standard. This compound has been developed as a new lead compound for pharmacological studies and drug development, with an emphasis on high purity standards. The CAS number for this compound is 1373038-56-2.</p>Formule :C16H14N2O3SDegré de pureté :Min. 95%Masse moléculaire :314.36 g/mol3-[2-[4-(6-Fluoro-2-benzoxazolyl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
CAS :<p>3-[2-[4-(6-Fluoro-2-benzoxazolyl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one is a synthetic compound that functions as a drug product. It is not found in nature and has been synthesized for use as an API impurity. The CAS number for this compound is 1005191-81-0. 3-[2-[4-(6-Fluoro-2 -benzoxazolyl)-1 -piperidinyl]ethyl]-6,7,8,9 tetrahydro 2 methyl 4H pyrido 1 2 a pyrimidin 4 one has been studied in metabolism studies. It is also known to have niche applications in analytical chemistry and research and development.</p>Formule :C23H27FN4O2Degré de pureté :Min. 95%Masse moléculaire :410.48 g/mol3'-Acetyl-4'-(2,3-epoxypropoxy)butyranilide
CAS :<p>3'-Acetyl-4'-(2,3-epoxypropoxy)butyranilide is an impurity found in the drug product of 3'-acetyl-4'-(2,3-epoxypropoxy)butyranilide hydrochloride. It has a molecular weight of 268.9 and chemical formula C12H18O6N2. 3'-Acetyl-4'-(2,3-epoxypropoxy)butyranilide is a synthetic compound that can be used as an analytical reference material for HPLC standardization or as an impurity standard for synthesis.</p>Formule :C15H19NO4Degré de pureté :Min. 95%Masse moléculaire :277.32 g/molN1-Losartanyl-losartan
CAS :<p>N1-Losartanyl-losartan is a new nonpolar, innovative pharmaceutical agent that fulfills the needs of pharmacological research. It has been shown to be pharmacologically active in vivo and in vitro. N1-Losartanyl-losartan has been shown to be genotoxic impurities, nitrosamines, and other impurities. N1-Losartanyl-losartan is an analytical method for the determination of valsartan and its metabolites. The analytical method uses supercritical fluid chromatography with mass spectroscopy detection (SFC/MSD).</p>Formule :C44H44Cl2N12ODegré de pureté :95%NmrMasse moléculaire :827.81 g/mol2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol N-oxide
CAS :<p>2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol N-oxide is a peroxide that is used in pharmaceutical preparations as an antioxidant. It is a white solid that is insoluble in water and has a molecular weight of 168.13. 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol N-oxide has been shown to be effective against the development of cholesterol gallstones and can be used as a prophylactic agent against cardiovascular disease. This compound also inhibits the oxidation of drugs by hydrogen peroxide and other oxidizing agents. 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)eth</p>Formule :C21H25N3O3SDegré de pureté :Min. 95%Couleur et forme :Tan to pale orange solid.Masse moléculaire :399.51 g/mol5-(Aminosulfonyl)-2-methoxy-benzoic acid methyl ester
CAS :<p>5-(Aminosulfonyl)-2-methoxy-benzoic acid methyl ester is a synthetic compound that is used for pharmaceutical preparations. It is typically prepared by the reaction of ethylene and chloroacetic acid in the presence of an organic solvent. The reaction time can be adjusted to produce the desired amount of 5-(aminosulfonyl)-2-methoxy-benzoic acid methyl ester. This synthetic compound has been shown to have a high yield, with minimal contaminating impurities. It has also been shown to be effective in both pharmaceutical dosage and calibration.</p>Formule :C9H11NO5SDegré de pureté :Min. 95%Masse moléculaire :245.25 g/molMethyl 3-aminocrotonate
CAS :<p>Methyl 3-aminocrotonate is an intermediate in the synthesis of pyridinedicarboxylic acid. It is a white powder with a melting point of 160-165°C and a boiling point of 263°C. Methyl 3-aminocrotonate is soluble in water, alcohols, ethers, chloroform, and benzene. It has been detected by its UV absorption at 227 nm. The detection sensitivity for this compound was found to be 0.1 ppm. This product has shown to produce calcium stearate as an acid conjugate.<br>Methyl 3-aminocrotonate is a molecule that contains a hydrogen bond between the hydroxyl group and the amine group on C3, which are both in close proximity to the carbonyl group on C2. This molecule exhibits intramolecular hydrogen bonding between two hydrogen atoms on different molecules. <br>The IR spectrum for methyl 3-aminoc</p>Formule :C5H9NO2Degré de pureté :Min. 95%Couleur et forme :White To Yellow SolidMasse moléculaire :115.13 g/mol4'-[(1,4'-Dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl][1,1'-biphenyl]-2-carboxamide
CAS :<p>Imatinib is a drug substance that belongs to the class of imidazole and phenylpiperidine derivatives. It is used in the treatment of leukemia and other cancers. Imatinib has been shown to inhibit tumor cell proliferation by inhibiting protein synthesis via inhibition of ribosomal activity, leading to cell death. Imatinib also inhibits the activation of PPARγ, an important transcription factor involved in lipid metabolism. The presence of impurities may affect the therapeutic efficacy or safety of this drug, so it is important to know what impurities are present in order to avoid unexpected side effects.</p>Formule :C33H31N5ODegré de pureté :Min. 95%Masse moléculaire :513.63 g/molChlorhexidine digluconate EP Impurity L
<p>Chlorhexidine digluconate EP Impurity L is a metabolite of chlorhexidine digluconate. It is an impurity found in the drug product, which is used for the treatment of skin and mucous membrane infections. The mechanism of action for chlorhexidine digluconate EP Impurity L is not known. However, it has been shown to be metabolized by CYP3A4 and CYP2C9 enzymes to form chlorhexidine acetate, a metabolite that inhibits bacterial growth, and hydrolyzed by esterases to form 2-hydroxychlorhexidine acetate. This metabolite has been found in the urine of rats following oral administration with chlorhexidine digluconate EP Impurity L.</p>Formule :C13H15ClN2O6Degré de pureté :Min. 95%Masse moléculaire :330.72 g/mol6-Amino-5-ethyl-5-phenyl-2,4(3H,5H)-pyrimidinedione
CAS :<p>Phenobarbital impurity B is an analytical reference material that is available as a HPLC standard and a CAS No. 58042-96-9. This material has been used in research and development of drugs, specifically as an API impurity for the drug product. Phenobarbital impurity B is a metabolite that can be found in the urine of patients taking phenobarbital. It has shown to have pharmacopoeia standards. Custom synthesis and natural are possible methods for obtaining this material. Synthetic is the most common method for generating this substance.</p>Formule :C12H13N3O2Degré de pureté :Min. 95%Masse moléculaire :231.25 g/mol3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]sulfinyl]-N-(aminosulfonyl)propanimidamide
CAS :<p>3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]sulfinyl]-N-(aminosulfonyl)propanimidamide is a drug product that is custom synthesized. It has a purity of ≥ 98% and is used in analytical, metabolism studies, natural drug development, pharmacopoeia, and research and development. 3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]sulfinyl]-N-(aminosulfonyl)propanimidamide has an impurity standard of 5% and can be found under CAS No. 90237-03-9.</p>Formule :C8H15N7O3S3Degré de pureté :Min. 95%Masse moléculaire :353.45 g/mol1-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-5-hydroxy-1-pentanone
CAS :<p>1-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-5-hydroxy-1-pentanone is a drug product that is used as an HPLC standard. It is a natural metabolite of the drug product 1-[4-(4-Amino-6,7-dimethoxyquinazolinyl)-1piperazinyl]-5hydroxypentane. The synthesis of this compound has been reported in the literature.<br>The impurity content of this compound meets the pharmacopoeia requirements for an analytical reference standard for API impurities.</p>Formule :C19H27N5O4Degré de pureté :Min. 95%Masse moléculaire :389.45 g/molIsopropyl 2-(3-nitrobenzilidene)acetoacetate
CAS :<p>This isopropyl 2-(3-nitrobenzylidene)acetoacetate is a reaction solution that can be used to produce the antihypertensive drug, methyldopa. The reaction time required for this solution to react is about two hours. This product also contains chloride and calcium antagonist, which are added as catalysts. The rate of this reaction depends on the temperature and concentration of organic solvent. Crotonic acid, dihedral, and the yield of this reaction depend on the purity of reagents. Impurities in this product include isobutyl and methylbenzene, but these are not harmful to human health. This product also contains piperazine and thionyl chloride as impurities.</p>Formule :C14H15NO5Degré de pureté :Min. 95%Masse moléculaire :277.27 g/molN2-Methyl alfuzosin hydrochloride (1:1)
CAS :<p>N2-Methyl alfuzosin hydrochloride (1:1) is a synthetic compound that is used as an impurity standard for the drug product Alfuzosin. It has been shown to be metabolized by the liver, and its metabolites are excreted through the bile. The N2-methyl group of this compound provides a marker for metabolism studies and it has been shown to inhibit bacterial growth in vitro.</p>Formule :C19H28ClN5O4Degré de pureté :Min. 95%Masse moléculaire :425.91 g/molAlfuzosin hydrochloride EP Impurity F hydrochloride
CAS :<p>Alfuzosin EP Impurity F hydrochloride is a drug product that is used as an analytical standard for Alfuzosin hydrochloride. It is a natural, synthetic, and impurity standard that exhibits similar chromatographic properties to the API. The CAS number of this impurity is 19216-68-3. This product has a niche market because it is used in metabolism studies. It also exhibits high purity and pharmacopoeia grade quality.</p>Formule :C12H16N4O2•HClDegré de pureté :Min. 95%Masse moléculaire :284.74 g/molN-(5,6-Dichloro-1,4-dihydro-2-quinazolinyl)-2,3-dihydroxypropanamide 2,2,2-trifluoroacetate
CAS :<p>N-(5,6-Dichloro-1,4-dihydro-2-quinazolinyl)-2,3-dihydroxypropanamide 2,2,2-trifluoroacetate is an analytical reference standard that can be used as a high purity drug product impurity in HPLC. It also has niche application as an API impurity and is a metabolite of the drug quinine.</p>Formule :C13H12Cl2F3N3O5Degré de pureté :Min. 95%Masse moléculaire :418.15 g/mol2-[[4-[2-(Cyclopropylmethoxy)ethyl]phenoxy]methyl]oxirane
CAS :<p>2-[4-[2-(Cyclopropylmethoxy)ethyl]phenoxy]methyloxirane is a metabolite of the drug product 2-[[4-[2-(Cyclopropylmethoxy)ethyl]phenoxy]methyl]oxirane. It is an impurity in the drug product, which is a pharmaceutical intermediate that has been shown to have pharmacological properties. The CAS number for this compound is 63659-17-6 and it has been assigned the Chemical Abstracts Service (CAS) number of 63659-17-6. This compound has been characterized using HPLC and GC/MS methods.</p>Formule :C15H20O3Degré de pureté :Min. 95%Masse moléculaire :248.32 g/mol4-Methyl-5-[(2-aminoethyl)thiomethyl]imidazole dihydrochloride
CAS :<p>4-Methyl-5-[(2-aminoethyl)thiomethyl]imidazole dihydrochloride is a synthetic drug product that has been purified to high purity. This compound is used as an analytical standard and impurity in the development of drugs. 4-Methyl-5-[(2-aminoethyl)thiomethyl]imidazole dihydrochloride is a metabolite of imidazole, which is a natural substance with unknown pharmacological activity. It has been found to be an impurity in the synthesis of various pharmaceuticals, including metronidazole and ampicillin. This product has not yet been evaluated for safety or efficacy in humans.</p>Formule :C7H13N3S·2HClDegré de pureté :Min. 95%Masse moléculaire :244.19 g/mol1,4-Bis(2,3,4-trimethoxybenzyl)piperazine
CAS :Produit contrôlé<p>1,4-Bis(2,3,4-trimethoxybenzyl)piperazine (1,4BTMP) is a piperazine derivative that has been shown to have inotropic properties. 1,4BTMP appears to increase the force of contraction of the heart muscle by increasing intracellular calcium levels. This drug may also be useful in the treatment of ventricular fibrillation and other arrhythmias. It has been shown that 1,4BTMP protects against lipid peroxidation induced by hydrogen chloride and hydrochloric acid in isolated rat hearts. In addition, this compound has been shown to inhibit creatine kinase activity and reduce lipid peroxide formation.</p>Formule :C24H34O6Degré de pureté :Min. 95%Masse moléculaire :418.52 g/mol1-[[2-[(2-Aminophenyl)amino]-5-methyl-3-thienyl]carbonyl]-4-methyl-piperazine
CAS :<p>Please enquire for more information about 1-[[2-[(2-Aminophenyl)amino]-5-methyl-3-thienyl]carbonyl]-4-methyl-piperazine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C17H22N4OSDegré de pureté :Min. 95%Masse moléculaire :330.45 g/molrac-Benzyl phenylephrone hydrochloride
CAS :Produit contrôlé<p>Rac-Benzyl phenylephrone hydrochloride is a synthetic compound that is not found in nature. It can be used as an analytical standard or a pharmacopoeia impurity standard. Rac-Benzyl phenylephrone hydrochloride has been shown to inhibit the activity of CYP3A4, an enzyme which metabolizes many drugs. As a result, it may be useful for drug development and research and could have applications in niche markets such as natural products.</p>Formule :C16H18ClNO2Degré de pureté :Min. 95%Masse moléculaire :291.77 g/mol(S)-5-Chloronaproxen
CAS :<p>(S)-5-Chloronaproxen is a synthetic drug product with a purity of 99.9%. It has been synthesized from natural, custom synthesis and analytical grade raw materials. Metabolism studies have been conducted to determine the metabolic pathways of (S)-5-chloronaproxen. The metabolite profile was analyzed by HPLC, and the impurity standard was developed for use in pharmacopoeia, niche research and development, and quality control laboratories.</p>Formule :C14H13ClO3Degré de pureté :Min. 95%Masse moléculaire :264.7 g/mol2-[(R)-[(1S)-2-Methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetic acid
CAS :<p>2-[(R)-[(1S)-2-Methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetic acid is a metabolite of the drug product, 2-[(S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinic acid. It is an impurity standard for the analytical determination of 2-[(S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinic acid in both drug products and in synthetic intermediates. The pharmacopoeia states that this compound should be present at less than or equal to 1% in drug products. This metabolite has been shown to have antiinflammatory activity.</p>Formule :C19H29O6PDegré de pureté :Min. 95%Masse moléculaire :384.4 g/mol2,12-Dihydro-1,3-dimethyl-9-methoxy-12-thioxobenzo [4,5] pyrido [1,2-c] imidazo [1,2-a] imidazol-2-one
CAS :<p>2,12-Dihydro-1,3-dimethyl-9-methoxy-12-thioxobenzo [4,5] pyrido [1,2-c] imidazo [1,2-a] imidazol-2-one is a synthetic compound that has not been evaluated in humans. This compound is an impurity standard for the synthesis of an API. The purity of this compound is >98% and it has been shown to be stable under acidic conditions.</p>Formule :C16H13N3O2SDegré de pureté :Min. 95%Masse moléculaire :311.36 g/mol5-Dimethylaminobutyryl citalopram
CAS :<p>5-Dimethylaminobutyryl citalopram is a metabolite of the antidepressant drug, Citalopram. It is used as an analytical impurity standard for Citalopram in HPLC and LCMS analysis. 5-Dimethylaminobutyryl citalopram is also a natural product of metabolism and may be found in humans. 5-Dimethylaminobutyryl citalopram has been shown to have similar pharmacological properties to Citalopram in animal studies, which include antihistamine effects and analgesic effects. This compound may be useful as a niche treatment for some patients who are resistant to other drugs.</p>Formule :C25H33FN2O2Degré de pureté :Min. 95%Masse moléculaire :412.54 g/mol4-[(2,3,4-Trimethoxyphenyl)methyl]-1-piperazinecarboxylic acid ethyl ester
CAS :<p>4-[(2,3,4-Trimethoxyphenyl)methyl]-1-piperazinecarboxylic acid ethyl ester is an impurity standard for HPLC. It is a white or off-white solid that is soluble in organic solvents. The compound has been shown to be a metabolite of the drug product, and can also be found as an impurity in the API. 4-[(2,3,4-Trimethoxyphenyl)methyl]-1-piperazinecarboxylic acid ethyl ester can be synthesized from 2,3,4-trimethoxybenzoic acid and 1-(2-chloroethyl)piperazine.</p>Formule :C17H26N2O5Degré de pureté :Min. 95%Masse moléculaire :338.4 g/mol(3R,5R)-Pitavastatin Calcium Salt
CAS :<p>(3R,5R)-Pitavastatin Calcium Salt is a drug product that is used in the development of pharmaceuticals. It is a synthetic compound with an impurity standard and a metabolite impurity. The CAS number for this product is 254452-96-5. (3R,5R)-Pitavastatin Calcium Salt has been shown to be metabolized by CYP2C9 and CYP2C8 enzymes, which may result in a decrease in potency or activity. This product also has been shown to have anti-inflammatory properties and inhibit the production of inflammatory mediators such as prostaglandins and leukotrienes. (3R,5R)-Pitavastatin Calcium Salt was prepared by solid phase synthesis using a fluorous biphasic approach.</p>Formule :C25H24FNO4CaDegré de pureté :Min. 95%Couleur et forme :White/Off-White SolidMasse moléculaire :441.5 g/molValdecoxib impurity I
CAS :<p>Valdecoxib impurity I is a synthetic compound that is used as an impurity standard for the drug product Valdecoxib. It has a CAS number of 1373038-59-5 and is used in HPLC analysis to detect the presence of metabolites. Valdecoxib impurity I has been shown to be a metabolite of Valdecoxib, but the metabolic pathway has not been elucidated.</p>Formule :C16H15N3O5S2Degré de pureté :Min. 95%Masse moléculaire :393.44 g/molN-[(3-Trifluoromethyl)phenyl)propyl] cinacalcet HCl
CAS :<p>N-[(3-Trifluoromethyl)phenyl)propyl] cinacalcet HCl is an analytical standard that is used as a HPLC impurity standard and an impurity in the synthesis of pharmaceutical drugs. It is also used as a pharmacopoeia reference material for the determination of purity, quality, and identity of drugs. This compound has been assigned a CAS number of 1271930-15-4 (free base). N-[(3-Trifluoromethyl)phenyl] propyl] cinacalcet HCl is one of the metabolites formed from cinacalcet hydrochloride, which is prescribed to treat secondary hyperparathyroidism in postmenopausal women.</p>Formule :C32H31F6N·HClDegré de pureté :Min. 95%Masse moléculaire :580.05 g/mol4'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxylic acid
CAS :<p>4'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxylic acid (4BMBCA) is a chemical compound that is used as an analytical method in drug discovery and development. It has been shown to have contraceptive properties, which may be due to its ability to inhibit the synthesis of progesterone. 4BMBCA has also been shown to reduce the development of primary tumors in mice. The drug is also able to cause stomatitis and show antimicrobial resistance in humans. Symptoms of this drug include fever, nausea, vomiting, diarrhea, headache, and stomatitis. 4BMBCA has been found by plasma mass spectrometry to be effective against several bacteria types including Staphylococcus aureus and Escherichia coli.</p>Formule :C14H11BrO2Degré de pureté :Min. 95%Masse moléculaire :291.14 g/molMirtazapine N-oxide
CAS :<p>Mirtazapine N-oxide is an antidepressant agent that is metabolized to mirtazapine. Mirtazapine N-oxide has been shown to have a linear response in the detection of serotonin in urine samples and has been used for pharmacokinetic studies, optimization, and clinical use. The enantiomer of mirtazapine N-oxide has been shown to be more potent than the racemic mixture. The drug is excreted unchanged into the urine with a half-life of 2 hours. Mirtazapine N-oxide can be detected in plasma for up to 24 hours after oral administration and may accumulate in certain tissues such as liver or kidney. This drug has also been shown to cause death in mice at very high doses.</p>Formule :C17H19N3ODegré de pureté :Min. 95%Masse moléculaire :281.35 g/molCinacalcet impurity E hydrochloride
CAS :<p>Cinacalcet is a drug product that is used for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease. It is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. Cinacalcet impurity E hydrochloride (CIN-E) is an analytical standard for use in HPLC as an impurity of cinacalcet. This compound has not been found to be pharmacologically active and its effects are unknown.</p>Formule :C22H25N·HClDegré de pureté :Min. 95%Masse moléculaire :339.9 g/molRegorafenib metabolite M2 oxide
CAS :<p>Regorafenib metabolite M2 oxide (M2O) is a cancer drug that is an inhibitor of multikinase. It was developed as a prodrug for regorafenib, which is used to treat patients with metastatic colorectal cancer and has been shown to be effective against other cancers, such as lung and pancreatic cancer. M2O inhibits the efflux of drugs from cells by binding to the transporter protein P-glycoprotein. This prevents the accumulation of toxic concentrations of regorafenib in cells, which are responsible for its side effects, such as diarrhea and liver damage. The uptake of M2O by cells is also inhibited by light and acidic conditions. Oral administration of M2O leads to increased exposure to regorafenib in the body because it is not metabolized by CYP3A4 enzymes.</p>Formule :C21H15ClF4N4O4Degré de pureté :Min. 95%Masse moléculaire :498.81 g/mol1-Desmethyl granisetron
CAS :Produit contrôlé<p>1-Desmethyl granisetron is an impurity found in the synthesis of granisetron hydrochloride. It is a white to off-white crystalline substance which is soluble in water, methanol, and ethanol. 1-Desmethyl granisetron has a molecular weight of 328.4 and exhibits efficient pharmacological properties similar to those of granisetron hydrochloride.</p>Formule :C17H22N4ODegré de pureté :Min. 95%Masse moléculaire :298.38 g/mol(RS)-N-[(1-Ethylpyrrolidin-2-yl)methyl]-2-hydroxy-5-sulphamoylbenzamide
CAS :<p>(RS)-N-[(1-Ethylpyrrolidin-2-yl)methyl]-2-hydroxy-5-sulphamoylbenzamide is a white to off-white crystalline powder. It is soluble in methanol and ethanol, but insoluble in water. It has an assay of >98% (HPLC), and a purity of >99% (HPLC). This compound is used as an analytical standard for the determination of impurities in other compounds. It is also used as a pharmacopoeia standard for the determination of metabolites in pharmaceutical preparations. This compound can be synthesized from either natural or synthetic sources.</p>Formule :C14H21N3O4SDegré de pureté :Min. 95%Masse moléculaire :327.4 g/molDutasteride EP impurity E
CAS :<p>Please enquire for more information about Dutasteride EP impurity E including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C27H30F6N2O2Degré de pureté :Min. 95%Masse moléculaire :528.54 g/mol(R)-Pramipexole 2HCl
CAS :Produit contrôlé<p>Dopamine (D2 and D3) receptor agonist; has anti-parkinsonian effects</p>Formule :C10H19Cl2N3SDegré de pureté :Min. 95%Masse moléculaire :283.067671,4-Bis[(tetrahydro-2-furanyl)carbonyl]-piperazine
CAS :<p>1,4-Bis[(tetrahydro-2-furanyl)carbonyl]-piperazine is a synthetic drug product. It is used as an analytical standard to help elucidate the metabolic pathway of drugs and their metabolites. This compound has been shown to be metabolized by various enzymes including CYP450, glutathione reductase, and esterases. It can also be synthesized from 1,4-dihydropyridine and 2-furancarboxaldehyde. The physical properties of 1,4-bis[(tetrahydro-2-furanyl)carbonyl]-piperazine are: white powder; mp 178°C; IR max 1710 cm−1 (CO); UV max 221 nm (EtOH). The impurities in this product are: 1-(2H)-Quinolinone (CAS No. 2467-94-1) which may have a maximum concentration</p>Formule :C14H22N2O4Degré de pureté :Min. 95%Masse moléculaire :282.34 g/mol5,6-Dehydro-17β-dutasteride
CAS :<p>5,6-Dehydro-17beta-dutasteride is a synthetic drug product that is used as an analytical standard for the determination of metabolites and impurities in pharmaceuticals. It also has been used as a natural metabolite, which can be found in human urine. 5,6-Dehydro-17beta-dutasteride is a metabolite of dutasteride, which is an antiandrogen medication for the treatment of benign prostatic hyperplasia (BPH). It is also known to inhibit the metabolism of other drugs such as ketoconazole and metoprolol.</p>Formule :C27H28F6N2O2Degré de pureté :Min. 95%Masse moléculaire :526.51 g/mol4',4'''-[(4'-Methyl-2'-propyl[2,6'-bi-1H-benzimidazole]-1,1'-diyl)bis(methylene)]bis[1,1'-biphenyl]-2-carboxylic acid
CAS :<p>4',4'''-[(4'-Methyl-2'-propyl[2,6'-bi-1H-benzimidazole]-1,1'-diyl)bis(methylene)]bis[1,1'-biphenyl]-2-carboxylic acid is an analytical reagent that is used in research and development as a drug product impurity standard. This compound has been shown to be metabolized by cytochrome P450 1A1 and 2C8 to form 4-hydroxybenzoic acid and 4,4''-[(4'-methyl-2' propyl-[2,6']bi-1H-benzimidazol-1,1' diyl)bis(methylene)]bis[3-(4-hydroxyphenyl)-propionic acid], respectively. 4',4''-[(4'-Methyl-2' propyl-[2,6']bi-1</p>Formule :C46H38N4O4Degré de pureté :Min. 95%Masse moléculaire :710.82 g/mol(+/-)N-Methyl-y-[3-(trifluoromethyl)-phenoxy]benzenepropanamine hydrochloride
CAS :<p>N-Methyl-y-[3-(trifluoromethyl)-phenoxy]benzenepropanamine hydrochloride is a synthetic drug product that has been shown to be metabolized in humans. It is an impurity standard for HPLC and analytical methods. This compound is used as a research chemical in the development of drugs, and is also used as a pharmacopoeia reference standard.</p>Formule :C17H18F3NO·HClDegré de pureté :Min. 95%Masse moléculaire :345.79 g/mol5-Ethyl-5-phenyl-2-(1-phenylpropyl)dihydropyrimidine-4,6(1H,5H)-dione
CAS :<p>5-Ethyl-5-phenyl-2-(1-phenylpropyl)dihydropyrimidine-4,6(1H,5H)-dione is an impurity in the drug product of the drug 5-[3-(3,4-dihydroisoquinolin-2(1H)-yl)propoxy]-2,2'-bis[N-(2-hydroxyethyl)]ethaneamine. It is an analytical standard for HPLC and can be used as a pharmacopoeia or custom synthesis. It is also a metabolite of the drug 5-[3-(3,4-dihydroisoquinolin-2(1H)-yl)propoxy]-2,2'-bis[N-(2-hydroxyethyl)]ethaneamine.</p>Formule :C21H24N2O2Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :336.43 g/mol3-[(1E)-2-[4-[[(2-Carboxyethyl)amino]carbonyl]phenyl]diazenyl] balsalazide
CAS :<p>3-[(1E)-2-[4-[[(2-Carboxyethyl)amino]carbonyl]phenyl]diazenyl] balsalazide is a white to off-white solid that is soluble in water and acidic solutions. It has an impurity level of less than 0.5%. The melting point of 3-[(1E)-2-[4-[[(2-Carboxyethyl)amino]carbonyl]phenyl]diazenyl] balsalazide is approximately 195°C. This compound has been shown to have antibiotic activity against a variety of bacteria, including methicillin resistant Staphylococcus aureus (MRSA).</p>Formule :C27H24N6O9Degré de pureté :Min. 95%Masse moléculaire :576.51 g/molEthosuximide impurity A
CAS :<p>Ethosuximide impurity A is a fluorinated compound that inhibits the enzyme acetylcholinesterase. It has been shown to inhibit the catalytic mechanism of acetylcholinesterase, which leads to its inhibitory effect on the enzyme. The compound does not have any structural similarity to the other known inhibitors of this enzyme. Ethosuximide impurity A has been shown to be an antimutagen and anticarcinogen in vitro, with a postulated mechanism of action that involves inhibition of a water molecule from binding to the active site.</p>Formule :C7H12O4Degré de pureté :Min. 95%Masse moléculaire :160.17 g/molBisoprolol impurity G
CAS :<p>Bisoprolol impurity G is a metabolite of bisoprolol. It is the standard for bisoprolol impurities and is used as an analytical reference material for the quality control of bisoprolol.</p>Formule :C19H33NO5Degré de pureté :Min. 95%Masse moléculaire :355.47 g/mol2-Amino-5,6-dichloro-3(4H)-quinazoline acetic acid hydrobromide
CAS :<p>2-Amino-5,6-dichloro-3(4H)-quinazoline acetic acid hydrobromide is a drug product that is Custom synthesized. It has a high purity and analytical quality. Metabolism studies have been conducted on this compound. Natural and synthetic sources are available for this compound. It is found in the Drug Development section of the pharmacopoeia. The CAS number for this compound is 1194434-39-3, and it has an Impurity Standard as well as an HPLC standard.</p>Formule :C10H10BrCl2N3O2Degré de pureté :Min. 95%Masse moléculaire :355.02 g/molRivaroxaban impurity 79
CAS :<p>Please enquire for more information about Rivaroxaban impurity 79 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C38H38N4O12Degré de pureté :Min. 95%Masse moléculaire :742.74 g/mol5-O-Desethyl amlodipine
CAS :<p>5-O-Desethyl amlodipine is a metabolite of amlodipine. It has been used as an analytical reference standard for the determination of amlodipine and its metabolites in human plasma and urine. 5-O-Desethyl amlodipine has been reported to be excreted in human breast milk at a concentration that is about 20% of that found in maternal plasma. The drug product is manufactured by HPLC and is classified as a high purity pharmaceutical drug, which means it is free from extraneous substances such as other drugs, proteins, or bacteria.</p>Formule :C18H21ClN2O5Degré de pureté :Min. 95%Masse moléculaire :380.82 g/mol(2S,4S)-4-Cyclohexyl-1-(1,3 dioxopentyl)-L-proline
CAS :Produit contrôlé<p>(4S)-4-Cyclohexyl-1-(1,3 dioxopentyl)-L-proline is a synthetic, non-natural amino acid. It is a metabolite of the pharmaceutical drug product (2,5-dioxohexahydro-2H-pyrrolo[3,4-c]pyrazol-1(2H)-yl)acetic acid and has been used as an analytical impurity standard. The chemical formula for (4S)-4-Cyclohexyl-1-(1,3 dioxopentyl)-L-proline is C13H24N2O6. This compound has been synthesized by reacting 4S - 1,3 - dioxopentane with L - proline in the presence of sodium amide. The synthesis was conducted in a solvent mixture of methylene chloride/dimethylformamide (1:1). The molecular</p>Formule :C16H25NO4Degré de pureté :Min. 95%Masse moléculaire :295.37 g/mol6,7,8,9-Tetrahydro-3-[2-[4-(6-methoxy-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
CAS :<p>A custom synthesis of 6,7,8,9-tetrahydro-3-[2-[4-(6-methoxy-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-2-methyl-4H-[1]pyrido[1,2-a]pyrimidin-4one<br>A synthetic analog of the natural product erythromycin A.<br>Metabolite: 3-[2-[4-(6-Methoxybenzo[d][1,3]dioxol-5(4H)-yl)-1piperidinyl)ethyl]-6,7,8,9 tetrahydro 4H pyrido [1',2' a] pyrimidin 4 one<br>Impurity: 1-(6 methoxy benzisoxazol 3 yl) piperidine<br>Custom synthesis: yes<br>High purity: yes</p>Formule :C24H30N4O3Degré de pureté :Min. 95%Masse moléculaire :422.52 g/mol(1RS)-1-(6-Methoxy-2-naphthyl)ethanol
CAS :<p>(1RS)-1-(6-Methoxy-2-naphthyl)ethanol is a multiphase test drug that exhibits reactive properties. It reacts with hydrogen to form hydrogen bonds and is insensitive to sephadex g-100. This compound also forms hydrogen bond with acetyl groups, which can be observed in the strain of the molecule. (1RS)-1-(6-Methoxy-2-naphthyl)ethanol has a primary alcohol group and can be easily acetylated. UV irradiation causes this compound to fluoresce, making it useful in kinetic studies.</p>Formule :C13H14O2Degré de pureté :Min. 95%Masse moléculaire :202.25 g/molN2-Losartanyl-losartan
CAS :<p>N2-Losartanyl-losartan is a drug product that has a CAS number of 230971-72-9. This product is an analytical standard for the metabolites of losartan, which is a drug used to treat high blood pressure and heart failure. Metabolism studies have shown that losartan is metabolized by hydroxylation, glucuronidation, and oxidation by cytochrome P450 enzymes. Losartan has also been found to be converted into an active metabolite in the body, which is called N2-hydroxy-losartan. It has been shown to be more potent than losartan at blocking angiotensin II receptors.</p>Formule :C44H44Cl2N12ODegré de pureté :Min. 95%Masse moléculaire :827.81 g/mol[6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl](4-hydroxyphenyl)-methanone
CAS :<p>MDM2 inhibitors are a class of cancer drugs that inhibit the activity of MDM2, which is an oncoprotein that prevents the degradation of p53. This inhibition leads to increased levels of p53 and the activation of its tumor-suppressing functions. The anti-cancer activity of this drug has been shown in a number of cancer cells, including human colon cancer cells, human prostate cancer cells, and murine leukemia cells. Furthermore, this drug has been shown to have synergistic effects when combined with other chemotherapeutic agents such as cisplatin and vincristine.</p>Formule :C21H14O4SDegré de pureté :Min. 95%Masse moléculaire :362.4 g/molSalbutamol Impurity D
CAS :<p>Salbutamol Impurity D is a chiral, metal chelator impurity of the drug substance Salbutamol. It is a prodrug that is hydrolyzed to its active form, salbutamol sulfate, in vivo. Salbutamol Impurity D binds to chloride ions and has been shown to be an interferent for many analytical methods. The reversed-phase chromatography retention time for Salbutamol Impurity D is about 10 minutes shorter than for Salbutamol sulfate.</p>Formule :C13H19NO3Degré de pureté :Min. 95%Masse moléculaire :237.29 g/molBrexpiprazole impurity 3
CAS :<p>Brexpiprazole impurity 3 is a drug product that has been custom synthesized for research purposes. The purity of this product is high and it has been analyzed using analytical methods. This product can be used to study the metabolism of brexpiprazole, which is an atypical antipsychotic medication. Brexpiprazole impurity 3 also has pharmacopoeia standards, which can be used to develop new drugs or as a quality control standard in research and development.</p>Formule :C25H27N3O3SDegré de pureté :Min. 95%Masse moléculaire :449.57 g/mol(3S,4S,3’S)-Ezetimibe
CAS :<p>Please enquire for more information about (3S,4S,3’S)-Ezetimibe including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C24H21F2NO3Degré de pureté :Min. 95%Masse moléculaire :409.43 g/mol
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