Dérivés de Quinazoline et de Quinoléine
Les quinazolines et les quinoléines sont des composés hétérocycliques azotés à structure aromatique qui jouent un rôle clé dans la synthèse de médicaments à activité anticancéreuse, antimicrobienne et anti-inflammatoire. Leurs dérivés présentent des modifications structurelles qui optimisent leur biodisponibilité et leur sélectivité, permettant ainsi le développement de nouveaux principes actifs pour diverses applications thérapeutiques. Ces composés sont utilisés dans la fabrication d’API destinés au traitement du cancer, des infections, des maladies neurodégénératives et cardiovasculaires. De plus, les dérivés de quinazoline et de quinoléine sont essentiels dans la recherche d’inhibiteurs enzymatiques et dans la conception de molécules bioactives innovantes.
Chez CymitQuimica, nous proposons des dérivés de quinazoline et de quinoléine de haute pureté pour des applications en synthèse chimique, développement pharmaceutique et biotechnologie.
65615 produits trouvés pour "Dérivés de Quinazoline et de Quinoléine"
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Iproniazid
CAS :Produit contrôlé<p>Applications Iproniazid is a hydrazine based drug used as an antidepressant. Iproniazid acts as an irreversible and nonselective monoamine oxidase inhibitor.<br>References Fagervall, I. et al.: Biochem. Pharmacol., 35, 1381 (1986); Horita, A.: Princ. Psychopharmacol., 279 (1970); O'Donnell, J.M. et al.: Psychopharmacology, 78, 214 (1982);<br></p>Formule :C9H13N3OCouleur et forme :White SolidMasse moléculaire :179.22Repirinast-d4
CAS :Produit contrôléFormule :C20H17D4NO5Couleur et forme :NeatMasse moléculaire :359.411-Nitroso-4-phenylpiperazine
CAS :Produit contrôlé<p>Applications Metabolite of N-Phenylpiperazine (P336040) found in wastewater treatment facilities.<br>References Jung, C. et al., Appl. Environ. Microb., 74, 6147 (2008)<br></p>Formule :C10H13N3OCouleur et forme :NeatMasse moléculaire :191.23Cilostazol-d4
CAS :Produit contrôlé<p>Applications Cilostazol-d4 is the labeled analogue of Cilostazol (C441500), a potent phosphodiesterase III A (PDE3A) inhibitor (IC50=0.2uM) and inhibitor of adenosine uptake. Has antimitogeni, antithrombotic, vasodilatory and cardiotonic properties in vivo. Also affects lipid levels in vivo.<br>References Suri, A., et al.: J. Clin. Pharmacol., 38, 144 (1998); Park, S.-W., et al.: Am. J. Cardiol., 84, 511 (1999); Tsuchikane, E., et al.: Circulation, 100, 21 (1999)<br></p>Formule :C20H23D4N5O2Couleur et forme :NeatMasse moléculaire :373.49D 13223-d4 (Flupirtine Metabolite)
CAS :Produit contrôlé<p>Applications The major active labelled metabolite of Flupirtine in human plasma. A potassium channel opener<br>References Niebch, G., et al.: Arzneim.-Forsch., 42, 1343 (1992), Friedel, H., et al.: Drugs, 45, 548 (1993), Fu, I., et al.: J. Pharm. Biomed. Anal., 18, 347 (1998),<br></p>Formule :C14H12D4ClFN4OCouleur et forme :NeatMasse moléculaire :314.78rac 6-Chloro-1,4-dihydro-4-(1-pentynyl)-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one
CAS :Produit contrôlé<p>Applications An Efavirenz (E425000) impurity.<br></p>Formule :C14H11ClF3NO2Couleur et forme :Off White SolidMasse moléculaire :317.693-Des(2-methoxyethyl) 3-(1-Methylethyl) Ester Nimodipine
CAS :Produit contrôlé<p>Impurity Nimodipine EP Impurity B<br>Applications 3-Des(2-methoxyethyl) 3-(1-Methylethyl) Ester Nimodipine (Nimodipine EP Impurity B) can be used in synthetic preparation of dihydropyridinedicarboxylic acid esters by methylimidazolium trifluoroacetate-catalyzed Hantzsch cyclocondensation reaction of oxo-carboxylic acid esters with aldehydes and ammonium acetate. It can also be used as an analyte for analytical study in developing and optimizing a validated isocratic reversed-phase high-performance liquid chromatograhy separation of nimodipine and impurities in tablets using experimental. design methodology. It is an impurity of the drug Nimodipine (N478200).<br>References Avalani, J. R., et al.: J. Chem. Sci., 124, 1091-1096 (2012); Barmpalexis, P., et al.: J. Pharmaceut. Biomed., 49, 1192-1202 (2009)<br></p>Formule :C21H26N2O6Couleur et forme :NeatMasse moléculaire :402.44ent-Rotigotine
CAS :<p>Applications It is a non-ergot dopamine agonist drug and is indicated for the treatment of Parkinson’s disease.<br>References Loschmann, P., et al.: Eur. J. Pharmacol., 166, 373 (1989), Edgar, D., et al.: J. Pharmacol. Exp. Ther., 283, 757 (1997), Ferreira, J., et al.: Lancet, 355, 1333 (2000), Arnulf, I., et al.: Neurology, 58, 1019 (2002), Wisor, J., et al.: Neuroscience, 132, 1027 (2005),<br></p>Formule :C19H25NOSCouleur et forme :Brown OilyMasse moléculaire :315.47Methylphenidate Carboxylic Acid Hydrochloride
CAS :Produit contrôlé<p>Applications O-Desmethyl Methylphenidate Carboxylic Acid is a derivative of Methylphenidate Hydrochloride (M325880), controlled substance (stimulant). CNS stimulant. Methylphenidate Carboxylic Acid Hydrochloride is a 4:1 Mixture of R533105 (DL-erythro Ritalinic Acid Hydrochloride) and R533110 (DL-threo-Ritalinic Acid Hydrochloride)<br>References Greenblatt, E.N., et al.: J. Pharmacol. Exp. Ther., 131, 115 (1961), Padmanabhan, G.R., Anal. Profiles Drug Subs., 10, 473 (1981), Srinivas, N.R., et al.: Pharm. Res., 10, 14 (1993),<br></p>Formule :C13H17NO2·HClCouleur et forme :Off-WhiteMasse moléculaire :255.742-(6-Methoxy-2-naphthyl)acetonitrile
CAS :Produit contrôlé<p>Applications 2-(6-Methoxy-2-naphthyl)acetonitrile (cas# 71056-96-7) is a compound useful in organic synthesis.<br></p>Formule :C13H11NOCouleur et forme :NeatMasse moléculaire :197.233,3'-Disulfanediylbis[(2S)-2-methylpropanoic] Acid
CAS :Produit contrôléFormule :C8H14O4S2Couleur et forme :NeatMasse moléculaire :238.322-Chloro-1,1,1-trimethoxyethane
CAS :Produit contrôlé<p>Applications 2-Chloro-1,1,1-trimethoxyethanen is a reactant in the synthesis of α-chloro-β-aminosulfinyl imidates as chiral building blocks<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Col0paert, F., et. al.: J. Org. Chem., 76, 2204 (2011)<br></p>Formule :C5H11ClO3Couleur et forme :NeatMasse moléculaire :154.59O-Desmethyl Indomethacin-d4
CAS :Produit contrôlé<p>Applications The major labelled metabolite of Indomethacin.<br>References Lewis, R., et al.: J. Clin. Invest., 53, 1607 (1974), Alvan, G., et al.: Clin. Pharmacol. Ther., 18, 364 (1975), Mungall, D., et al.: J. Pharm. Sci., 73, 1000 (1984), Baldwin, S., et al.: Xenobiotica, 25, 261 (1995),<br></p>Formule :C18H10D4ClNO4Couleur et forme :NeatMasse moléculaire :347.79N-Nitroso Amodiaquine
Produit contrôléFormule :C20H21ClN4O2Couleur et forme :NeatMasse moléculaire :384.8592-Des(5-methyl-1,3,4-oxadiazole-2-carboxamide) 2-(2-(2-Acetylhydrazinyl)-2-oxoacetamide) Raltegravir
CAS :<p>Applications 2-Des(5-methyl-1,3,4-oxadiazole-2-carboxamide) 2-(2-(2-Acetylhydrazinyl)-2-oxoacetamide) Raltegravir is an impurity of a potent human immunodeficiency virus (HIV) integrase inhibitor. A novel anti-AIDS drug.<br>References Wade, K., et al.: J. Pharmacol. Biomed. Anal., 8, 401 (1990), Hazuda, D., et al.: Science, 287, 646 (2000), Williams, J., et al.: Drug Metab. Dispos., 32, 1201 (2004), Duckett, C., et al.: Xenobiotica, 36, 59 (2006), Miners, J., et al.: Biochem. Pharmacol., 71, 1531 (2006), Summa, V., et al.: J. Med. Chem., 49, 6646 (2006),<br></p>Formule :C20H23FN6O6Couleur et forme :Off-WhiteMasse moléculaire :462.43Perampanel-d5 (1.0mg/ml in Acetonitrile)
CAS :Produit contrôléFormule :C23D5H10N3OCouleur et forme :ColourlessMasse moléculaire :354.421-(1H-Benzo[d]imidazol-2-yl)-3-methyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid Sodium Salt
CAS :<p>Applications 1-(1H-Benzo[d]imidazol-2-yl)-3-methyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid is an impurity of Rabeprazole. It is also a degradation product formed in stressed tablets of Rabeprazole sodium.<br>References Kommanaboyina, B., et al.: Drug Dev. Ind. Pharm., 25, 857 (1999); Carswel, C., et al.: Drugs, 61, 2327 (2001); Garcia, C., et al.: J. Pharm. Biomed. Anal., 46, 88 (2008)<br></p>Formule :C14H10N3NaO3Couleur et forme :NeatMasse moléculaire :291.24Valdecoxib Sulfonic Acid
CAS :Produit contrôlé<p>Applications Valdecoxib Sulfonic Acid is a metabolite of the potent and specific inhibitor of cyclooxygenase-2, Valdecoxib (V090000).<br>References Zhang, J.I. et al.: Drug Metab. Dispos., 31, 491 (2003); Yuan, J.J. et al.: Drug Metab. Dispos., 30, 1013 (2002);<br></p>Formule :C16H13NO4SCouleur et forme :White To Off-WhiteMasse moléculaire :315.34N-[4-[[(Z)-(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)phenylmethyl]amino]phenyl]-N,4-dimethyl-1-piperazineacetamide
CAS :Produit contrôlé<p>Applications N-[4-[[(Z)-(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)phenylmethyl]amino]phenyl]-N,4-dimethyl-1-piperazineacetamide was used in the study to discover a potent inhibitor of MELK that inhibits expression of the anti-apoptotic protein Mcl-1 and TNBC cell growth. N-[4-[[(Z)-(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)phenylmethyl]amino]phenyl]-N,4-dimethyl-1-piperazineacetamide is an impurity of Intedanib (I666650), which is an antitumor agent.<br>References Edupuganti, R., et al.: Bioorg. Med. Chem., 25, 2609 (2017); Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)<br></p>Formule :C29H31N5O2Couleur et forme :NeatMasse moléculaire :481.59N-[[N-Methyl-N-[(2-isopropyl]-4-thiazolyl)methyl)amino]carbonyl-L-valine Carboxylic Acid
CAS :Produit contrôlé<p>Impurity Ritonavir EP Impurity A<br>Applications N-[[N-Methyl-N-[(2-isopropyl]-4-thiazolyl)methyl)amino]carbonyl-L-valine Carboxylic Acid (Ritonavir EP Impurity A) is an intermediate in the synthesis of Ritonavir.<br>References Hamada, Y., et al.: Bioorg. Med. Chem., 10, 4155 (2002),<br></p>Formule :C14H23N3O3SCouleur et forme :NeatMasse moléculaire :313.42L-threo-Methylphenidate Hydrochloride
CAS :Produit contrôlé<p>Applications Controlled substance. CNS stimulant. The less potent threo-enantiomer of Methylphenidate. The threo enantomers have shown that the pharmacological activity residues predominantly in the d-threo enantiomer.<br>References Greenblatt, E.N., et al.: J. Pharmacol. Exp. Ther., 131, 115 (1961), Padmanabhan, G.R., et al.: Anal. Profiles Drug Subs., 10, 473 (1981), Kuczenski, R., et al.: J. Pharmacol. Exp. Ther., 296, 876 (2001), Pelham, W.E., et al.: J. Consult. Clin. Psychol., 61, 506 (1993), Srinivas, N.R., et al.: Pharm. Res., 10, 14 (1993),<br></p>Formule :C14H19NO2·ClHCouleur et forme :NeatMasse moléculaire :269.77MRX-2843
CAS :Produit contrôlé<p>Applications MRX-2843, is an orally available small-molecule inhibitor of both MERTK and FLT3.<br>References Minson, K. A. et al.: JCI Insight. 2016 Mar;1(3):e85630.;<br></p>Formule :C29H40N6OCouleur et forme :NeatMasse moléculaire :488.67Plerixafor-d4
CAS :Produit contrôlé<p>Stability Very Hygroscopic<br>Applications Labelled Plerixafor, it is a hematopoietic stem cell (HSC) mobilizer that inhibits the CXCR4 chemokine receptor and blocks binding of its ligand, stromal cell-derived factor-1-α (SDF-1-α). This agent was approved on Dec. 15, 2008, as treatment in combination with granulocyte-colony stimulating factor (G-CSF) to mobilize HSCs to the peripheral blood for collection and subsequent autologous transplantation in patients with non-Hodgkin's lymphoma (NHL) and multiple myeloma (MM).<br>References Xie, T., et al.: Science, 290, 328 (2000), Leone, D., et al.: J. Pharmacol. Exp. Ther., 305, 1150 (2003), Chigaev, A., et al.: J. Immunol. 178, 6828 (2007), Kiel, M., et al.: Cell Stem Cell, 1, 204 (2007),<br></p>Formule :C28H50D4N8Couleur et forme :Off White SolidMasse moléculaire :506.811,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid Diethyl Ester
CAS :Produit contrôléFormule :C19H22N2O6Couleur et forme :YellowMasse moléculaire :374.39DL-threo-Droxidopa-d3 Hydrochloride Salt Hydrate
CAS :Produit contrôlé<p>Applications DL-threo-Droxidopa-d3 Hydrochloride Salt Hydrate is an isotope labeled compound of DL-threo-Droxidopa (D689950), a synthetic amino acid precursor of Norepinephrine. An Antiparkinson.<br>References Bartholini, J., et al.: J. Pharmacol. Exp. Ther ., 193, 523 (1975), Kato, T., et al.: Biochem. Pharmacol., 36, 3051 (1987), Kawabata, A., et al.: Br J. Pharmacol., 111, 503 (1994)<br></p>Formule :C9H8D3NO5•HCl•x(H2O)Couleur et forme :NeatMasse moléculaire :216.2136461802Nicoboxil
CAS :Produit contrôlé<p>Applications Nicoboxil is a medication used in the treatment of acute non-specific low back pains.<br>References Gaubitz, M., et al.: Eur. J. Pain , 20, 263 (2016),<br></p>Formule :C12H17NO3Couleur et forme :ColourlessMasse moléculaire :223.274-O-Des(difluoromethyl) Roflumilast
CAS :Produit contrôléFormule :C16H14Cl2N2O3Couleur et forme :NeatMasse moléculaire :353.20Tipiracil Hydrochloride
CAS :Produit contrôlé<p>Applications Tipiracil Hydrochloride serves as a treatment for metastatic colorectal cancer (mCRC). A thymidine phosphorylase inhibitor.<br>References Sugita, K., et al.: Oncol., 91, 224-230 (2016); van der Velden, D. L., et al.: Clin. Cancer Res., 22, 2835-2839 (2016)<br></p>Formule :C9H11ClN4O2·(HCl)Couleur et forme :White To Off-WhiteMasse moléculaire :242.66 + (36.46)Varenicline-d2,15N2 Dihydrochloride
CAS :Produit contrôlé<p>Applications Varenicline-d2,15N2 Dihydrochloride, is the labelled dihydrochloride salt of Varenicline (V098492), a nicotinic α4β2 acetylcholine receptor partial agonist. Aids in smoking cessation.<br>References Benowitz, N., et al.: Clin. Pharmacol. Ther., 44, 23 (1988), Cohen, C., et al.: J. Pharmacol. Exp. Ther., 306, 407 (2003), Tapper, A., et al.: Science, 306, 1029 (2004), Coe, J., et al.: J. Med. Chem., 48, 3474 (2005), Obach, R., et al.: Drug Metab. Disp., 34, 121 (2006),<br></p>Formule :C13H13D2Cl2N15N2Couleur et forme :Light Beige SolidMasse moléculaire :288.183-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzenamine
CAS :Produit contrôlé<p>Stability Air Sensitive<br>Applications 3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzenamine is used in the preparation of c-Src and Abl inhibitors based on the scaffold present in Imatinib (G407000), used in the treatment of myelogenic leukemia. It is a COVID19-related research product.<br>References Seeliger, M. et al.: Canc. Res., 69, 2384 (2009); Schindler, T., et al.: Science, 289, 1938 (2000); Drucker, B.J., et al.: N. Engl. J. Med., 344, 1031 (2001)<br></p>Formule :C11H10N3F3Couleur et forme :NeatMasse moléculaire :241.21Methyl 5,6,7,8-Tetradehydro Risperidone
CAS :Produit contrôlé<p>Applications An internal standard for Risperidone (R525000).<br>References Jannssen, P.A.J., et al.: J. Pharmacol. Exp. Ther., 244, 685 (1988), Gelders, Y.G., et al.: Pharmacopsychiatry, 23, 206 (1990), Green, B.: Curr. Med. Res. Opin., 16, 57 (2000)<br></p>Formule :C24H25FN4O2Couleur et forme :White To Off WhiteMasse moléculaire :420.483-Ethynylaniline
CAS :Produit contrôlé<p>Stability Light Sensitive<br>Applications Reagent in the preparation of a metabolite of Erlotinib (E625000).<br></p>Formule :C8H7NCouleur et forme :Colourless To Dark RedMasse moléculaire :117.15Efavirenz 1-Desamine-1-oxy
Produit contrôlé<p>Applications Efavirenz 1-Desamine-1-oxy is an analog of Efavirenz (E425000), a nonnucleoside HIV-1 reverse transcriptase inhibitor. Antiviral.<br>References Young, S.D., et al.: Antimicrob. Ag. Chemother., 39, 2602 (1995)<br></p>Formule :C14H8ClF3O3Couleur et forme :NeatMasse moléculaire :316.66Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro Dasatinib
CAS :Produit contrôlé<p>Applications Intermediate in the preparation of Dasatinib metabolite, used in the treatment of cancers and immune diseases. It is a COVID19-related research product.<br></p>Formule :C16H13Cl2N5O2SCouleur et forme :NeatMasse moléculaire :410.28N-Ethylcarbamic Acid 3-[(1S)-1-(Dimethylamino)ethyl]phenyl Ester
CAS :Produit contrôléFormule :C13H20N2O2Couleur et forme :NeatMasse moléculaire :236.31Erismodegib
CAS :Produit contrôlé<p>Applications A potent, selective and orally bioavailable Smoothened (SMO) antagonist; it inhibits hedgehog (Hh) signaling pathway via antagonism of the Smoothened receptor (SMO). Antineoplastic. Potent Hedgehog inhibitor.<br>References Berman, D., et al.: Science, 297, 1559 (2002), Varjosalo, M., et al.: Cell, 133, 537 (2008), Theunissen, J., et al.: Cancer Res., 69, 6007 (2009),<br></p>Formule :C26H26F3N3O3Couleur et forme :NeatMasse moléculaire :485.507-Demethyl Ivabradine Hydrochloride
CAS :Produit contrôlé<p>Applications Ivabradine (I940500) metabolite.<br>References Duffull, S., et al.: Eur. J. Pharm. Sci., 10, 285 (2000), Portoles, A., et al.: J. Clin. Pharmacol., 46, 1195 (2006),<br></p>Formule :C26H34N2O5·HClCouleur et forme :NeatMasse moléculaire :491.02Clonidine
CAS :Produit contrôlé<p>Applications Clonidine is an α2-Adrenergic agonist. Antihypertensive; analgesic for neuropathic pain.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Roach, A.G., et al.: J. Pharmacol. Exp. Ther., 227, 421 (1983); Glassman, A.H., et al.: Science, 226, 864 (1984); Abounassif, A.M., et al.: Anal. Profiles Drug Subs. Excip., 21, 109 (1992);<br></p>Formule :C9H9Cl2N3Couleur et forme :NeatMasse moléculaire :230.092-((3-Fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid
CAS :Produit contrôlé<p>Applications 2-((3-Fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid (cas# 1289942-66-0) is a useful research chemical.<br></p>Formule :C12H15FN2O3Couleur et forme :NeatMasse moléculaire :254.26rac trans-2-Phenylcyclopropylamine Hydrochloride
CAS :Produit contrôlé<p>Applications Non-selective MAO-A/B inhibitor.<br>References Stout, S.C., et al.: J. Pharmacol. Exp. Ther., 300, 1085 (2002),<br></p>Formule :C9H11N·ClHCouleur et forme :NeatMasse moléculaire :169.65N’-Benzylidene-2-ethoxybenzimidohydrazide Hydroiodide
Produit contrôléFormule :C16H17N3O·HICouleur et forme :Off-WhiteMasse moléculaire :395.238(4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-2-(4-methoxyphenyl)-4-(trifluoromethyl)-2H-3,1-benzoxazine(Mixture of 2 Diastereomers)
CAS :Produit contrôlé<p>Applications An impurity arising in the synthesis of Efavirenz (E425000).<br>References Chen, C., et al.: Enantiomer, 4, 599 (1999), Young, S.D., et al.: Antimicrob. Ag. Chemother., 39, 2602 (1995),<br></p>Formule :C21H17ClF3NO2Couleur et forme :NeatMasse moléculaire :407.81N-Methyl Topiramate
CAS :Produit contrôlé<p>Impurity Topiramate N-methyl impurity<br>Applications N-Methyl Topiramate, is an impurity of Topiramate (T540250); which is an anticonvulsant (antiepilepsy) drug, that has been approved for weight loss by FDA.<br>References Maryanoff, B.E., et al.: J. Med. Chem., 30, 880 (1987), Bialer, M.: Clin. Pharmacokinet., 24, 441 (193),<br></p>Formule :C13H23NO8SCouleur et forme :NeatMasse moléculaire :353.39rac N-Desmethyl Mephenytoin-D5 (Major)
CAS :Produit contrôlé<p>Applications An anticonvulsant, hypnotic. A labelled metabolite of Mephentoin.A representative lot was 85% d5; 15% d4 1% d3 with no detectable d0.<br>References Karlaganis, G., et al.: Drug Metab. Dispos., 8, 173 (1980), Knabe, J., et al.: Arch. Phar., 313, 538 (1980),<br></p>Formule :C112H5H7N2O2Couleur et forme :NeatMasse moléculaire :209.26N-Nitroso-desethyl-Hydroxychloroquine
Produit contrôléFormule :C16H21ClN4O3Couleur et forme :NeatMasse moléculaire :336.817(R)-9-Hydroxy Risperidone
CAS :Produit contrôlé<p>Applications The R-enantiomer metabolite of Risperidone (R525000), a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tiberghien, F., et al.: Anticancer Drugs, 7, 568 (1996), Kansy, M., et al.: J. Med. Chem., 41, 1007 (1998), Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001), Kerr, K., et al.: J. Biol. Chem., 276, 8657 (2001), Doran, A., et al.: Drug Metab. Dispos., 33, 165 (2005),<br></p>Formule :C23H27FN4O3Couleur et forme :NeatMasse moléculaire :426.48Rilmazafone Hydrochloride
CAS :<p>Applications Rilmazafone Hydrochloride can be used in biological study of nitrazepam or rilmazafone hydrochloride combined with ethanol effects on human memory. It is also used as sleep aid medication.<br>References Suzuki, M., et al.: Neurosciences (Okayama, Japan), 20, 43 (1994)<br></p>Formule :C21H20Cl2N6O3·HClCouleur et forme :NeatMasse moléculaire :475.33 + (36.46)Risperidone 9-Ethylidenecarboxylate Hydrochloride
Produit contrôlé<p>Applications Risperidone 9-Ethylidenecarboxylate Hydrochloride, is the derivative of Risperidone (R525000), which is combined serotonin (5-HT2) and dopamine (D2) receptor antagonist, used for the treatment of schizophrenia, bipolar disorder and behavior problems in people with autism.<br>References Tiberghien, F., et al.: Anticancer Drugs, 7, 568 (1996), Kansy, M., et al.: J. Med. Chem., 41, 1007 (1998), Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001), Kerr, K., et al.: J. Biol. Chem., 276, 8657 (2001), Doran, A., et al.: Drug Metab. Dispos., 33, 165 (2005),<br></p>Formule :C25H27FN4O4Couleur et forme :NeatMasse moléculaire :466.503646N,N’-Desethylene Levofloxacin Hydrochloride
CAS :<p>Impurity Levofloxacin USP Related Compound E<br>Applications Levofloxacin (L360000) impurity. A photodegradation product of Levofloxacin (L360000) in aqueous solution. Levofloxacin USP Related Compound E.<br>References Yoshida, Y., et al.: Arzneim.-Forsch., 43, 601 (1993),<br></p>Formule :C16H18FN3O4·ClHCouleur et forme :Off White SolidMasse moléculaire :371.793-Chlorobenzyl Cyanide
CAS :Produit contrôlé<p>Applications 3-Chlorobenzyl Cyanide is a useful synthetic intermediate. It was used to design EGFR Tyrosine Kinase Inhibitors. It can also be used to synthesize imidoyl thioureas as non-nucleoside reverse transcriptase inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Traxler, P., et al.: J. Med. Chem., 42, 1018 (1999); Ludovici, D., et al.: Bioorg. Med. Chem. Lett., 11, 2225 (2001)<br></p>Formule :C8H6ClNCouleur et forme :NeatMasse moléculaire :151.593-Hydroxy-4-methoxybenzaldehyde
CAS :Produit contrôléFormule :C8H8O3Couleur et forme :NeatMasse moléculaire :152.15Zuclopenthixol (1 mg/mL In Methanol)
CAS :Formule :C22H25ClN2OSCouleur et forme :Single SolutionMasse moléculaire :400.96Denitro Tolcapone
CAS :Produit contrôléFormule :C14H12O3Couleur et forme :NeatMasse moléculaire :228.242-(Chloromethyl)-4-methoxy-3,5-dimethylpyridine Hydrochloride
CAS :Produit contrôlé<p>Impurity Omeprazole EP Impurity XI<br>Applications 2-(Chloromethyl)-4-methoxy-3,5-dimethylpyridine Hydrochloride (Omeprazole EP Impurity XI) is an intermediate in the production of the antiulcer agent Omeprazole.<br>References Roma, G., et al.: J. Med. Chem., 50, 2886 (2007), Hoffmann, S., et al.: Toxicol. Lett., 180, 9 (2008),<br></p>Formule :C9H12ClNO·ClHCouleur et forme :WhiteMasse moléculaire :222.11Flumequine Ethyl Ester
CAS :Produit contrôlé<p>Applications Flumequine Ethyl Ester is an impurity of Flumequine (F445000), a quinolone antibacterial.<br>References Stilwell, G., et al.: Antimicrob. Agents Chemother., 7, 483 (1975), Rohlfing, S.R., et al.: J. Antimicrob. Chemother., 3, 615 (1977),<br></p>Formule :C16H16FNO3Couleur et forme :NeatMasse moléculaire :289.306,8-Dioxo Apalutamide
CAS :Produit contrôlé<p>Applications 6,8-Dioxo Apalutamide is an impurity of Apalutamide (A726120). Apalutamide is a second-generation antiandrogen used in the treatment of prostate cancer.<br>References Li, Huifang, et al.: J. of Chem. Info. and Model., 53(1), 123-130 (2013);Joseph, James D., et al.: Cancer Disc., 3(9), 1020-1029 (2013)<br></p>Formule :C21H15F4N5O3Couleur et forme :NeatMasse moléculaire :461.383-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride
CAS :<p>Applications Sitagliptin intermediate.<br>References Mohri, K., et al.: Chem. Pharm. Bull., 30, 3097 (1982), Sarges, R., et al.: J. Med. Chem., 33, 2240 (1990), Cameron, M., et al.: J. Pharm. Biomed. Anal., 28, 137 (2002),<br></p>Formule :C6H7F3N4·ClHCouleur et forme :WhiteMasse moléculaire :228.603,5-Bis(chloromethyl)pyridine Hydrochloride
CAS :Produit contrôlé<p>Stability Unstable in Aqueous Solution<br>Applications 3,5-BIS(CHLOROMETHYL)PYRIDINE HCL (cas# 1210824-61-5) is a useful research chemical.<br></p>Formule :C7H7Cl2N•HClCouleur et forme :NeatMasse moléculaire :212.5Vortioxetine Lactose Adduct
Produit contrôlé<p>Stability Hygroscopic<br>Applications Vortioxetine Lactose Adduct, is an impurity of Vortioxetine (V766000), a multimodal serotonergic agent that inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT (1,2,3).<br>References Paunovic, A. et al.: ACS Chem. Biol., 12, 132 (2017);<br></p>Formule :C30H42N2O10SCouleur et forme :NeatMasse moléculaire :622.73Plerixafor Hydrochloride (1:8)
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Plerixafor Hydrochloride (1:8), is an immunostimulant used to mobilize hematopoietic stem cells in cancer patients. It is a hematopoietic stem cell (HSC) mobilizer that inhibits the CXCR4 chemokine receptor and blocks binding of its ligand, stromal cell-derived factor-1-α (SDF-1-α).<br>References Xie, T., et al.: Science, 290, 328 (2000), Leone, D., et al.: J. Pharmacol. Exp. Ther., 305, 1150 (2003), Chigaev, A., et al.: J. Immunol. 178, 6828 (2007), Kiel, M., et al.: Cell Stem Cell, 1, 204 (2007),<br></p>Formule :C28H54N8·8ClHCouleur et forme :NeatMasse moléculaire :794.47cis-Hydroxy Solifenacin N-Oxide(Mixture of Diastereomers)
Produit contrôlé<p>Applications Solifenacin (S676700) metabolite.<br></p>Formule :C23H26N2O4Couleur et forme :NeatMasse moléculaire :394.46Ketoconazole N-Oxide
CAS :Produit contrôlé<p>Applications Ketoconazole N-Oxide is an impure analogue of Ketoconazole (K186000) which inhibits cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo. Antimetastatic and antineoplastic activity. Orally active 5-lipoxygenase and thromboxane synthase inhibitor.<br>References Lambert, A., et al.: Biochem. Pharmacol., 35, 3999 (1986), Van Wauwe, J.P. and Janssen, P.A.J., J. Med. Chem., 32, 2231 (1989), Nardone, P.A., et al.: . Surg. Res., 44, 425 (1988), Tucker, W.F.G., et al.: Br. Med. J., 293, 882 (1986)<br></p>Formule :C26H28Cl2N4O5Couleur et forme :Off-WhiteMasse moléculaire :547.43Atazanavir-d9
CAS :Produit contrôlé<p>Applications Atazanavir-d9 is the deuterated analog of Atazanavir (A790051), a azapeptide HIV protease inhibitor derivative. Atazanavir have been investigated as potential treatment of human immunodeficiency virus (HIV) and for anticancer purposes.<br>References Musial, B.L., et al.: Am. J. Health Syst. Pharm., 61, 1365 (2004), Wood, R., et al.: J. Acquir. Immune Defic. Syndr., 36, 684 (2004),<br></p>Formule :C382H15H37N6O7Couleur et forme :NeatMasse moléculaire :719.95Lodoxamide
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Lodoxamide is an antiallergic drug that acts as a mast cell stabilizer. It is effective in the treatment of allergic conjunctivitis and in decreasing vascular permeability.<br>References Ciprandi, G., et al.: Allergy, 51(12), 946-951 (1996); Bayer, Atilla., et al.: Ophthalmologica, 217(2), 119-123 (2003)<br></p>Formule :C11H6ClN3O6Couleur et forme :NeatMasse moléculaire :311.63O-Desethyl Resiquimod-d6
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications O-Desethyl Resiquimod-d6 is the labelled analogue of O-Desethyl Resiquimod (D228575), which is derived from its parent compound Resiquimod (R144680), which is an imidazoquinoline derivative that acts as an immune response modifier. Resiquimod shows antitumor and antiviral activity and is used in the treatment of skin lesions such as herpes simplex virus. Resiquimod is a toll-like receptor 9 (TLR7) agonist.<br>References Wu, J.J. et al.: Antivir. Res., 64, 79 (2004); Fife, K.H. et al.: Antimicrob. Agents Chemother., 52, 477 (2008); Szeimies, R.M. et al.: Brit. J. Dermatol., 159, 205 (2008);<br></p>Formule :C15H12D6N4O2Couleur et forme :NeatMasse moléculaire :292.37Tadalafil Hydroxypiperidone
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Tadalafil Hydroxypiperidone, is an impurity of Tadalafil (T004500), a phosphodiesterase 5-inhibitor used for the treatment of erectile dysfunction.<br>References Carrier, S., et al.: Can. J. Urol., 10(1), 12 (2003), Doggrell, S.A., et al.: Expert Opin. Pharmacother., 6, 75 (2005), Forgue, S.T., et al.: Br. J. Clin. Pharmacol., 61, 280 (2005),<br></p>Formule :C22H19N3O6Couleur et forme :NeatMasse moléculaire :421.42-[[(3aR,4S,6R,6aS)-6-[[5-Amino-6-chloro-2-(propylthio)-4-pyrimidinyl]amino]tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol
CAS :Produit contrôlé<p>Applications 2-[[(3aR,4S,6R,6aS)-6-[[5-Amino-6-chloro-2-(propylthio)-4-pyrimidinyl]amino]tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol is used as a reagent in the synthesis of Ticagrelor (T437700) derivatives as antiplatelet agents.<br>References Zhang, H., et al.: Bioorg. Med. Chem. Lett., 22, 3598 (2012)<br></p>Formule :C17H27ClN4O4SCouleur et forme :NeatMasse moléculaire :418.94(R)-Desmethyl Citalopram Hydrochloride
CAS :Formule :C19H19FN2O·ClHCouleur et forme :NeatMasse moléculaire :346.83Lacidipine Monomethyl Ester
CAS :Produit contrôlé<p>Applications Lacidipine Monomethyl Ester is an impurity of Lacidipine (L098000); a dihydropyridine calcium channel blocker. Antihypertensive.<br>References Mohan, Arivozhi., et al.: J. AOAC Int., 94(6), 1800-1806 (2011); Safar, M., et al.: Clin. Pharmacol. Ther., 46, 94 (1989); Kharat, V.R., et al.: J. Pharm. Biomed. Anal., 28, 789 (2002); McCormack, A.J., et al.: Drugs, 63, 2327 (2003)<br></p>Formule :C25H31NO6Couleur et forme :NeatMasse moléculaire :441.524'-Desmethoxy-4'-chloro Moxonidine
CAS :Produit contrôlé<p>Impurity Moxonidine<br>Applications 4'-Desmethoxy-4'-chloro Moxonidine is an impurity of moxonidine.<br>References Milovanovic, S., et al.: J. Pharm. Biomed. Anal., 59, 151 (2012); Filipic, S., et al.: J. Liquid Chromatogr. Related Technol., 38, 1121 (2015)<br></p>Formule :C8H9Cl2N5Couleur et forme :NeatMasse moléculaire :246.10NAP 226-90-d6
CAS :Produit contrôléFormule :C102H6H9NOCouleur et forme :NeatMasse moléculaire :171.278-Hydroxy Efavirenz (~90%)
CAS :Produit contrôlé<p>Applications 8-Hydroxy Efavirenz is a metabolite of Efavirenz (E425000), a nonnucleoside HIV-1 reverse transcriptase inhibitor.<br>References Gorski, J., et al.: Biochem. Pharmacol., 47, 1643 (1994), Desta, Z., et al.: J. Pharmacol. Exp. Ther., 285, 428 (1998), Langmann, P., et al.: Eur. J. Med. Res., 7, 309(2002), Chang, T., et al.: Drug Metab. Dispos., 31, 7 (2003),<br></p>Formule :C14H9ClF3NO3Degré de pureté :~90%Couleur et forme :NeatMasse moléculaire :331.67Nitrofurantoin Monohydrate
CAS :Produit contrôlé<p>Applications 1-(((5-Nitrofuran-2-yl)methylene)amino)-imidazolidine-2,4-dione hydrate (CAS# 17140-81-7) is a useful research chemical compound.<br></p>Formule :C8H8N4O6Couleur et forme :YellowMasse moléculaire :256.185-(Ethoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3-pyridinecarboxylic Acid
CAS :Produit contrôléFormule :C17H18N2O6Couleur et forme :NeatMasse moléculaire :346.333-[2-[4-(6-Fluoro-2-benzoxazolyl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (Risperidone Impurity)
CAS :Produit contrôléFormule :C23H27FN4O2Couleur et forme :NeatMasse moléculaire :410.48N-(4-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
CAS :Produit contrôlé<p>Applications Intermediate in the preparation of Imatinib impurities. It is a COVID19-related research product.<br></p>Formule :C16H15N5Couleur et forme :NeatMasse moléculaire :277.325-Hydroxy Propranolol Hydrochloride
CAS :Produit contrôlé<p>Applications A metabolite of Propranolol.<br>References Otton, S., et al.: Br. J. Clin. Pharmacol., 30, 751 (1990), Fujita, S., et al.: J. Pharmacol. Exp. Ther., 264, 226 (1993), Bichara, N., et al.: Drug Metab. Dispos., 24, 112 (1996), Tasaki, T., et al.: J. Biochem., 123, 162 (1998),<br></p>Formule :C16H21NO3·HClCouleur et forme :NeatMasse moléculaire :311.804Loratadine-d5 (ethyl-d5)
CAS :Produit contrôlé<p>Applications Loratadine-d5 (ethyl-d5) (CAS# 1398065-63-8) is a useful isotopically labeled research compound.<br></p>Formule :C22D5H18ClN2O2Couleur et forme :NeatMasse moléculaire :387.924-Hydroxy Phenylbutazone
CAS :<p>Applications Impurity in the production of Phenylbutazone (P319570)<br>References Fricoteaux, R., et al.: J. Pharm. Biomed. Anal., 7, 1585 (1989), Segrestaa, J., et al.: Chem. Pharm. Bull., 50, 744 (2002),<br></p>Formule :C19H20N2O3Couleur et forme :White To Off-WhiteMasse moléculaire :324.371-(4-(4-(tert-Butyl)phenyl)-4-hydroxybutyl)-4-piperidinecarboxylic Acid Ethyl Ester
CAS :Produit contrôléFormule :C22H35NO3Couleur et forme :NeatMasse moléculaire :361.52N-Des(4-Fluorophenyl)-N-(3-chlorophenyl)-ezetimibe
CAS :Produit contrôléFormule :C24H21ClFNO3Couleur et forme :NeatMasse moléculaire :425.882-Hydroxy Imipramine β-D-Glucuronide
CAS :Produit contrôlé<p>Applications A metabolite of Imipramine.<br>References Gram, L.F., et al.: Clin. Pharmacol. Therap., 17, 555 (1975), Hackett, A.M., et al.: Xenobiotica, 14, 491 (1984), Chiba, M., et al.: Biochem. Pharmacol., 39, 367 (1990),<br></p>Formule :C25H32N2O7Couleur et forme :NeatMasse moléculaire :472.53Thiazol-5-ylmethyl ((2R,5R)-5-Amino-1,6-diphenylhexan-2-yl)carbamate Hydrochloride
CAS :Produit contrôlé<p>Applications Thiazol-5-ylmethyl ((2R,5R)-5-Amino-1,6-diphenylhexan-2-yl)carbamate Hydrochloride is an impurity of Cobicistat (C633150), a HIV protease inhibitor that has been coadministered with low-dose ritonavir (R535000) as a pharmacoenhancer.<br>References Von, H., Exp. Rev. Clin. Pharmacol., 5, 557 (2012); Lepist, E.I., et al.: Antimicrob. Agent. Chemother., 56, 5409 (2012); Orr, S.T.M., et al.: J. Med. Chem., 55, 4896 (2012)<br></p>Formule :C23H27N3O2S·HClCouleur et forme :NeatMasse moléculaire :446.0O-Desmethylsulpiride
CAS :Produit contrôléFormule :C14H21N3O4SCouleur et forme :NeatMasse moléculaire :327.401-(2,5-Dimethylphenyl)ethanol
CAS :Produit contrôlé<p>Applications 1-(2,5-Dimethylphenyl)ethanol can be used as a reagent in reactions or as a aroma compound<br>References Zhou, J., et al.: Yuanyi Xuebao., 37, 1621-1628 (2010)<br></p>Formule :C10H14OCouleur et forme :NeatMasse moléculaire :150.22Vortioxetine Hydrobromide (1 mg/mL in Methanol)
CAS :Formule :C18H22N2S·BrHCouleur et forme :Single SolutionMasse moléculaire :379.3584-(2-Pyridinyl)benzaldehyde
CAS :Produit contrôlé<p>Impurity Atazanavir Impurity (Pyridinyl Benzaldehyde)<br>Applications Reactive metabolite of atazanavir. Atazanavir Impurity; Pyridinyl Benzaldehyde impurity<br>References F. Li et al., Drug Metabolism and Disposition 39, 294 (2011)<br></p>Formule :C12H9NOCouleur et forme :NeatMasse moléculaire :183.21Haloperidol pyridinium Chloride Impurity
CAS :Produit contrôlé<p>Applications Haloperidol pyridinium Chloride is a neurotoxic pyridinium metabolite of haloperidol that is formed in the liver and found in the brain. Haloperidol pyridinium Chloride is a substrate for human organic cation transporters.<br>References Kang, H. et. al.: Drug Metab. Dispos., 34, 1145 (2006)<br></p>Formule :C21H18Cl2FNOCouleur et forme :NeatMasse moléculaire :390.28De(methypiperazinyl) Sildenafil Dimer Impurity
CAS :Produit contrôlé<p>Applications A related dimeric impurity of Sildenafil (S435000).<br></p>Formule :C34H38N8O6SCouleur et forme :NeatMasse moléculaire :686.78(3S)-1-[2-(3-Ethenyl-4-hydroxyphenyl)ethyl]-α,α-diphenyl-3-pyrrolidineacetamide
CAS :Produit contrôléFormule :C28H30N2O2Couleur et forme :NeatMasse moléculaire :426.55Verapamil Ethyl Methanethiosulfonate, Bromide
CAS :Produit contrôlé<p>Applications An analog of Verapamil. P Glycoprotein drug binding domain verapamil methanethiosulfonate. Useful for mapping the pore region of L-type calcium channels and Kv1.3 potassium channels.<br>References Loo, T., et al.: J. Biol. Chem., 270, 843 (1995), Sharom, F., et al.: J. Membr. Biol., 160, 161 (1997), Kim, R., et al.: J. Clin. Invest., 101, 289 (1998), Lee, C., et al.: Biochemistry., 37, 3594 (1998),<br></p>Formule :C30H45N2O6S2·BrCouleur et forme :NeatMasse moléculaire :673.725-(2-Fluorophenyl)-5-oxovaleric Acid
CAS :Produit contrôlé<p>Applications 5-(2-Fluorophenyl)-5-oxovaleric Acid is used as a reagent in the preparation of indole derivatives which act as cell protective agents. It is also used as a reagent in the catalytic N-nitroso aldol reaction of γ,δ-unsaturated δ-lactones.<br>References Yamamoto, I., et al.: Preparation of indole derivatives as cell protective agents, WO Patent 9745410, Dec 4, 1997; Yanagisawa, A., et al.: Org. Lett., 14, 2434 (2012);<br></p>Formule :C11H11FO3Couleur et forme :NeatMasse moléculaire :210.2XL518
CAS :Produit contrôlé<p>Applications A potent, selective, orally bioavailable inhibitor of MEK1, a component of the RAS/RAF/MEK/ERK pathway. It inhibits proliferation and stimulates apoptosis in a variety of human tumor cell lines. In preclinical xenograft models, oral administration of XL518 results in sustained inhibition of pERK in tumor tissue, but not brain tissue, leading to tumor growth inhibition and regression at well tolerated doses.<br>References Rosen, L.S. et al.: J. Clin. Oncol., 26, 14585 (2008);<br></p>Formule :C21H21F3IN3O2Couleur et forme :White To Off-WhiteMasse moléculaire :531.31Moxonidine
CAS :Produit contrôlé<p>Applications Moxonidine is an antihypertensive agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rayment, S., et al.: Brit. J. Pharmacol., 160, 1727 (2010), Taksande, B., et al.: Eur. J. Pharmacol., 637, 89 (2010), Nasr, M., et al.: Vas. Pharmacol., 53, 53 (2010),<br></p>Formule :C9H12ClN5OCouleur et forme :NeatMasse moléculaire :241.682-Methyl-5-nitroaniline
CAS :Produit contrôlé<p>Applications 2-Methyl-5-nitroaniline is used as a reagent in the synthesis of imatinib base derivatives which show antibacterial and antifungal activity. Also used as a reagent in the synthesis of pyrimidinylaminobenzene derivatives which exhibit antiproliferative activity against melanoma. Dyes and metabolites, Environmental Testing. It is a COVID19-related research product.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Patoliya, M.J., et al.: J. Chem., no vol., no pp. (2013); Kim, H.J., et al.: B. Korean Chem. Soc., 34, 2311 (2013)<br></p>Formule :C7H8N2O2Couleur et forme :YellowMasse moléculaire :152.15Anastrozole EP Impurity E (2-[3-(Cyanodimethylmethyl)-5-hydroxymethylphenyl]-2-methylpropionitrile)
CAS :Produit contrôlé<p>Impurity Anastrozole EP Impurity E<br>Applications 2-[3-(Cyanodimethylmethyl)-5-hydroxymethylphenyl]-2-methylpropionitrile (Anastrozole EP Impurity E ) is an impurity of Anastrozole (A637425), an aromatase inhibitor which functions as an antineoplastic (1,2). Anastrozole is used in post-menopausal women with advanced breast cancer.<br>References 1. Plourde, P. et al.: Breast Cancer Res Treat. 1994;30(1):103-112. Buzdar, A. et al.: Cancer. 1997 Feb 15;79(4):730-9.<br></p>Formule :C15H18N2OCouleur et forme :NeatMasse moléculaire :242.32(S)-(-)-O-Desmethyl Carvedilol
CAS :Produit contrôlé<p>Applications An optically active metabolite of Carvedilol (C184625), a nonselective ß-adrenergic blocker with α1-blocking activity. [α]D= -18.7 (c= 0.1 methanol)<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987), Fujimaki, M., et al.: Xenobiotica, 20, 1025 (1990), Ruffolo, R., et al.: Eur. J. Clin. Pharmacol., 38, S82 (1990), Clohs, L., et al.: J. Pharm. Biomed. Anal., 31, 407 (2003),<br></p>Formule :C23H24N2O4Couleur et forme :NeatMasse moléculaire :392.45Camostat Mesylate
CAS :Produit contrôléFormule :C20H22N4O5·CH4O3SCouleur et forme :NeatMasse moléculaire :494.52Desamino Imiquimod
CAS :Produit contrôléFormule :C14H15N3Couleur et forme :NeatMasse moléculaire :225.29Hydroxy Atrazine-d5
CAS :Produit contrôlé<p>Applications Labelled Hydroxy Atrazine (H828600). Hydroxy Atrazine is a major metabolite of Atrazine (A794600).<br>References Thurman, E., et al.: Environ. Sci. Technol., 26, 2440 (1992), Evgenidou, E., et al.: J. Agric. Food Chem., 50, 6423 (2002), Namiesnik, J., et al.: Anal. Bioanal. Chem., 381, 279 (2005), Hultgren, S., et al.: Anal. Bioanal. Chem., 393, 929 (2009),<br></p>Formule :C82H5H10N5OCouleur et forme :NeatMasse moléculaire :202.272-(4-(Methylsulfonamido)phenyl)acetic Acid
CAS :Produit contrôlé<p>Applications 2-(4-(Methylsulfonamido)phenyl)acetic Acid acts as a reagent for resiniferatoxin analogs preparation as metabolically stable TRPV1 agonists and potential analgesics. Preparation and structure-activity relationships of 2,6-diaryl-4-(phenacylamino)pyrimidines as selective adenosine A2A antagonists.<br>References Choi, H., et al.: Bioorg. Med. Chem. , 17, 690 (2009); Moorjani, M., et al.: Bioorg. Med. Chem. Lett., 18, 1269 (2008)<br></p>Formule :C9H11NO4SCouleur et forme :NeatMasse moléculaire :229.25N-Methyl-2-[[3-[(1Z)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide
CAS :Produit contrôlé<p>Applications N-Methyl-2-[[3-[(1Z)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide is an impurity of Axitinib (A794650), a tyrosine kinase inhibitor. Axitinib is used in cancer therapy.<br>References Wasser, K., et al.: Eur. Radiol., 13, 80 (2003), Park, J., et al.: Clin. Cancer Res., 8, 1172 (2002), Bergers, G., et al.: J. Clin. Invest., 111, 1287 (2003),<br></p>Formule :C22H18N4OSCouleur et forme :NeatMasse moléculaire :386.4695Ipidacrine-d9 (Major)
CAS :Produit contrôlé<p>Applications Ipidacrine-d9 (Major) is an isotopic analog of ipidacrine, which is used in biological studies as a possible treatment of toxic cognitive disorders.<br>References Fateev, I V., et al.: B. Exp. Biol. Med., 156, 353 (2014);<br></p>Formule :C12H8D9N2Couleur et forme :NeatMasse moléculaire :198.333,4-Dichloro Trazodone Dihydrochloride
CAS :Produit contrôlé<p>Applications 3,4-Dichloro Trazodone is the dichlorinated analogue and impurity of the antidepressant agent Trazodone (T718500).<br>References Pai, N.R. et al.: J. Chem. Pharmac. Res., 2, 458 (2010); Pai, N. et al.: Int. J. Pharmac. Sci. Rev. Res., 4, 180 (2010);<br></p>Formule :C19H21Cl2N5O•2HCiCouleur et forme :NeatMasse moléculaire :406.3123646Dimenhydrinate
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications An antihistamine with antiemetic properties used to prevent nausea and motion sicknes composed of two drugs 8-Chlorotheophylline (C411440) and Diphenhydramine (D486900).<br>References Sibel, K. et al.: Arzneim.-Forsch. , 52, 529 (2002); Pytel, J. et al.: Clin. Therap., 29, 84 (2007); Scholtz, A.W. et al.: Clin. Therap., 26, 866 (2004);<br></p>Formule :C17H21NO·C7H7ClN4O2Couleur et forme :NeatMasse moléculaire :469.966-Hydroxy-7-methoxy-4(1H)-quinazolinone
CAS :Produit contrôlé<p>Applications 6-Hydroxy-7-methoxy-4(1H)-quinazolinone is a reactant used in the preparation of 4-anilinoquinazoline derivatives that have shown antitumor activities. 6-Hydroxy-7-methoxy-4(1H)-quinazolinone was also used as a reactant in the synthetic preparation of 2-arylbenzothiazoles as kinase inhibitors.<br>References Chandregowda, V., et al.: Eur. J. Med. Chem., 44, 3046 (2009); Tasler, S., et al.: Bioorg. Med. Chem. Lett., 17, 6728 (2009);<br></p>Formule :C9H8N2O3Couleur et forme :BeigeMasse moléculaire :192.17Quetiapine Carboxylate Impurity
CAS :Produit contrôlé<p>Applications Quetiapine Carboxylate is an impurity of Quetiapine Hemifumarate (Q510000), an atypical antipsychotic agent used for the treatment of patients with schizophrenia, biopolar disorder and to treat major depressive disorder.<br>References Wetzel, H., et al.: Psychopharmacol., 119, 231 (1995); Bharathi, C., et al.: Pharmazie., 63, 14 (2008);<br></p>Formule :C22H25N3O4SCouleur et forme :Light Orange ColourMasse moléculaire :427.52Pamapimod
CAS :Produit contrôlé<p>Applications A selective inhibitor of the α-isoform of p38 MAP kinase. It is used in in treatment of patient with rheumatoid arthritis. Pamapimod was tolerable but not effective as Methotrexate.<br>References Guan, Z., et al.: J. Biol. Chem., 273, 12901 (1998), Lee, J., et al.: Pharmacol. Ther., 82, 389 (1999), Korb, A., et al.: Arthritis Rheum., 54, 2745 (2006),<br></p>Formule :C19H20F2N4O4Couleur et forme :WhiteMasse moléculaire :406.38(S,S)-Dihydro Bupropion β-D-Glucuronide
Produit contrôlé<p>Applications (S,S)-Dihydro Bupropion β-D-Glucuronide is a glucuronide metabolite of the drug Bupropion (B689625, HCl salt). Bupropion is a selective inhibitor of dopamine uptake.<br>References Soroko, F., et al.: J. Pharm. Pharmacol., 29, 769 (1977), Tucker, W.E., J. Clin. Psychiatry, 44, 60 (1983), Hsyu, P-H., et al.: J. Clin. Pharmacol., 37, 737 (1997), West, R., et al.: Expert Opin. Pharmacother., 4, 533 (2003),<br></p>Formule :C19H28ClNO7Couleur et forme :NeatMasse moléculaire :417.883-Amino-4-(2,4,5-trifluorophenyl)butanyl Sitagliptin
CAS :Produit contrôlé<p>Applications 3-Amino-4-(2,4,5-trifluorophenyl)butanyl Sitagliptin is an impurity of Sitagliptin (S490990). Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. It has recently been approved for the therapy of type II diabetes.<br>References Kim, D., et al.: J. Med. Chem., 48, 141 (2005), Ahren, B., et al.: Eur. J. Pharmacol., 521 164 (2005), Bergman, A., et al: Clin. Ther., 28, 55 (2006)<br></p>Formule :C26H23F9N6O2Couleur et forme :NeatMasse moléculaire :622.4854Levetiracetam-d6
CAS :Produit contrôlé<p>Applications The labelled (S)-enantiomer of Etiracetam (E932970) and the ethyl analog of Piracetam (P500800). Used as an anticonvulsant.<br>References Gower, A.J., et al.: Eur. J. Pharmacol., 222, 193 (1992); Kasteleijn-Noist Trenite, D.G.A., et al.: Epilepsy Res., 25, 225 (1996); Patsalos, P.N., et al.: Pharmacol. Ther., 85, 77 (2000),<br></p>Formule :C82H6H8N2O2Couleur et forme :BeigeMasse moléculaire :176.25Desalkyl Ebastine-d5
CAS :Produit contrôlé<p>Applications A labelled metabolite of Ebastine.<br>References Wiseman, L., et al.: Drugs, 51, 260 (1996), Takanori, H., et al.: Drug Metab. Dispos., 26, 566 (1998), Moss, A., et al.: Clin. Exp. Allergy 1999, 29, 200 (1999), Simons, F., et al.: Clin. Pharmacokinet., 36, 329 (1999), Hashizume, T., et al.: J. Pharmacol. Exp. Theor., 300, 298 (2002),<br></p>Formule :C18H16D5NOCouleur et forme :NeatMasse moléculaire :272.44-(Trifluoromethoxy)aniline
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications 4-(Trifluoromethoxy)aniline is used in the synthesis of anticancer agents and antitumor medicaments. Also, its an intermediate in the production of labelled Riluzole (R510000), a neuroprotective agent. Modulates glutamatergic transmission. A glutamate release inhibitor. An anticonvulsant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cilibrizzi, A., et al.: J. Med. Chem., 52, 5044 (2009), Verhaeghe, P., et al.: Bioorg. Med. Chem., 17, 4313 (2009), Chandregowda, V., et al.: Eur. J. Med. Chem., 44, 3046 (2009), Wahl, F., et al.: Eur. J. Pharmacol., 230, 209 (1993) Bensimon, G., et al.: N. Engl. J. Med., 330, 585 (1994); Piras, S. et al.: Eur. j. Med. Chem., 75, 169 (2014); Vyas, V. et al.: Eur. J. Med. Chem., 82, 385 (2014);<br></p>Formule :C7H6F3NOCouleur et forme :NeatMasse moléculaire :177.12Levomepromazine-D3 Sulfoxide
CAS :Produit contrôléFormule :C19D3H21N2O2SCouleur et forme :NeatMasse moléculaire :347.492,6-Dichloro-7-deazapurine
CAS :Produit contrôléFormule :C6H3Cl2N3Couleur et forme :NeatMasse moléculaire :188.01Paliperidone N-Oxide
CAS :Produit contrôlé<p>Impurity Paliperidone USP Related Compound D<br>Applications One of the major degradation product of Risperidone in bulk drug and pharmaceutical dosage forms. Paliperidone USP Related Compound D.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Leysen, J., et al.: J. Pharmacol. Exp. Ther., 247, 661 (1988), Huang, M., et al.: Pharm. Drug Dispos., 54, 257 (1993), Smyth, W., et al.: Anal. Bioanal. Chem., 378, 1305 (2004),<br></p>Formule :C23H27FN4O4Couleur et forme :NeatMasse moléculaire :442.48N-(2-Methyl-4-nitrophenyl)-4-(3-pyridinyl)-2-pyrimidinamine
CAS :Produit contrôlé<p>Applications Intermediate in the preparation of Imatinib impurities. It is a COVID19-related research product.<br>References Zimmermann., A., et al.: Bioorg. Med. Chem. Lett., 7, 187 (1997),<br></p>Formule :C16H13N5O2Couleur et forme :LightMasse moléculaire :307.31N-[(1S,2S,4S)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]carbamic Acid 5-Thiazolylmethyl Ester
CAS :Produit contrôlé<p>Impurity Ritonavir EP Impurity J<br>Applications N-[(1S,2S,4S)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]carbamic Acid 5-Thiazolylmethyl Ester (Ritonavir EP Impurity J) is an intermediate in the synthesis of Ritonavir (R535000), a selective HIV protease inhibitor used for the treatment of HIV infections and AIDS.<br>References Hamada, Y., et al.: Bioorg. Med. Chem., 10, 4155 (2002);<br></p>Formule :C28H35N3O5SCouleur et forme :White To Off-WhiteMasse moléculaire :525.66Benzil
CAS :<p>Applications Benzil is used in organic synthesis as a building block and in polymer chemistry as a photoinitiator. It has also been found to be an inhibitor of mammalian carboxylesterases.<br>References Encinas, M., et al.: J. Polym. Sci. A1., 22, 2469 (1984); Wadkins, R., et al.: J. Med. Chem., 48, 2906 (2005); Hicks, L., et al.: Bioorgan. Med. Chem., 15, 3801 (2007);<br></p>Formule :C14H10O2Couleur et forme :NeatMasse moléculaire :210.231-(1H-Benzo[d]imidazol-2-yl)-3-methyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid (>75%)
CAS :<p>Impurity Rabeprazole EP Impurity C<br>Applications 1-(1H-Benzo[d]imidazol-2-yl)-3-methyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid (>75%) (Rabeprazole EP Impurity C) is a Rabeprazole (R070500) impurity. A degradation product formed in stressed tablets of Rabeprazole sodium.<br>References Kommanaboyina, B., et al.: Drug Dev. Ind. Pharm., 25, 857 (1999), Carswel, C., et al.: Drugs, 61, 2327 (2001), Garcia, C., et al.: J. Pharm. Biomed. Anal., 46, 88 (2008),<br></p>Formule :C14H11N3O3Degré de pureté :>75%Couleur et forme :NeatMasse moléculaire :269.26Desacetyl Diltiazem-d4
CAS :Produit contrôlé<p>Applications A labelled metabolite of Diltiazem (D460620).<br></p>Formule :C20H20D4N2O3SCouleur et forme :NeatMasse moléculaire :376.51Elvitegravir-d6 (Major)
CAS :Produit contrôlé<p>Applications A novel labelled inhibitor of human immunodeficiency virus type 1 integrase.<br>References Chou, T., et al.: Eur. J. Biochem., 115, 207 (1981), Baba, M., et al.: Antimicrob. Agents Chemother., 31, 1613 (1987), Craigie, R., et al.: J. Biol. Chem., 276, 23213 (2001), Chen, X., et al.: J. Mol. Biol., 380, 504 (2008),<br></p>Formule :C23H17D6ClFNO5Couleur et forme :NeatMasse moléculaire :453.914-(Methylamino)-3-nitrobenzoic Acid
CAS :Produit contrôlé<p>Applications 4-(Methylamino)-3-nitrobenzoic Acid (cas# 41263-74-5) is a compound useful in organic synthesis.<br></p>Formule :C8H8N2O4Couleur et forme :NeatMasse moléculaire :196.16Bis(3-methylthien-2-yl)methanone
CAS :Produit contrôlé<p>Applications Bis(3-methylthien-2-yl)methanone is an impurity of Tiagabine (T436400), a GABA uptake inhibitor and nticonvulsant agent.<br>References Zhang, J.G., et al.: Chem. Res. Chin. Uni., 22, 351 (2006); Callen, G., et al.: Heterocycles., 39, 293 (1994);<br></p>Formule :C11H10OS2Couleur et forme :NeatMasse moléculaire :222.33N-[4-(Aminocarbonyl)-3-fluorophenyl]-2-methylalanine Methyl Ester
CAS :Produit contrôléFormule :C12H15FN2O3Couleur et forme :NeatMasse moléculaire :254.261-[6-(2-propenyl)-ergoline-8β-carbonyl]-3-methyl-perhydropyrimidine-2-one Methanolate
Produit contrôléFormule :C24H32N4O3Couleur et forme :NeatMasse moléculaire :424.54N’-[2-[2,4-(Dimethylphenyl)thio]phenyl] Vortioxetine
Produit contrôlé<p>Applications N’-[2-[2,4-Dimethylphenyl)thio]phenyl] Vortioxetine is an impurity of Vortioxetine (V766000, HBr salt) which is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT.<br>References Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011); Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012); Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013)<br></p>Formule :C32H34N2S2Couleur et forme :NeatMasse moléculaire :510.76N-Desethyl N-Methyl Rivastigmine
CAS :Produit contrôlé<p>Impurity Rivastigmine EP Impurity B<br>Applications N-Desethyl N-Methyl Rivastigmine (Rivastigmine EP Impurity B) is an impurity of Rivastigmine (R541000), a brain selective acetylcholinesterase inhibitor. Nootropic.<br>References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993),<br></p>Formule :C13H20N2O2Couleur et forme :NeatMasse moléculaire :236.32N-Sulfamoylethyl Naratriptan Pyridinium Chloride
CAS :Produit contrôlé<p>Impurity Naratriptan Impurity F<br>Stability Hygroscopic<br>Applications 4-[1,5-Bis-(2-methylsulfamoylethyl)-1H-indol-3-yl]-1-methylpyridinium Chloride is an impurity of Naratriptan (N378730).<br></p>Formule :C20H27ClN4O4S2Couleur et forme :NeatMasse moléculaire :487.042-Nitroso Riluzole
Produit contrôlé<p>Applications 2-Nitroso Riluzole is an impurity of Riluzole (R510000); is a neuroprotective agent. Modulates glutamatergic transmission. A glutamate release inhibitor. An anticonvulsant. Neuroprotective agent.<br>References Mizoule, J., et al.: Neuropharmacology, 24, 767 (1985), Wahl, F., et al.: Eur. J. Pharmacol., 230, 209 (1993) Bensimon, G., et al.: N. Engl. J. Med., 330, 585 (1994)<br></p>Formule :C8H3F3N2O2SCouleur et forme :Dark GreenMasse moléculaire :248.182Montelukast Cyclized Ether impurity
CAS :Produit contrôlé<p>Applications A cyclic ether impurity of antiasthmatic Montelukast (M568000).<br>References Egekeze, J.O. et al.: Anal. Chem., 67, 2292 (1995);<br></p>Formule :C29H26ClNOCouleur et forme :NeatMasse moléculaire :439.983-Hydroxy Anagrelide-13C3 (~80%)
CAS :Produit contrôlé<p>Applications 3-Hydroxy Anagrelide-13C3 is a major labelled metabolite of Anagrelide, an antithrombotic.<br>References Fleming, J., et al.: Thromb. Res., 15, 373 (1979), Gillespie, E., et al.: Biochem. Pharmacol., 37, 2866 (1988), Mazur, E., et al.: Blood, 79, 1931 (1992), Wang, G., et al.: Br. J. Pharmacol., 146, 324 (2005), Wagstaff, A., et al.: Drugs, 66, 111 (2006),<br></p>Formule :C713C3H7Cl2N3O2Degré de pureté :~80%Couleur et forme :NeatMasse moléculaire :275.07Losartan Carboxylic Acid Acyl-β-D-Glucuronide, 90%
CAS :Produit contrôlé<p>Applications A metabolite of Losartan (L470500).<br></p>Formule :C28H29ClN6O8Degré de pureté :90%Couleur et forme :NeatMasse moléculaire :613.02(S)-3-(Boc-amino)piperidine
CAS :Produit contrôlé<p>Applications Useful intermediate for the synthesis of a variety of chiral aminopiperidinyl quinolones as potent antibacterial agents against resistant pathogens; and alkynylpyrimidine amide derivatives as orally available inhibitors of Tie-2 kinase.<br>References Hu, X., et al.: J. Med. Chem., 46, 3655 (2003), Cee, V., et al.: J. Med. Chem., 50, 627 (2007),<br></p>Formule :C10H20N2O2Couleur et forme :NeatMasse moléculaire :200.28Everolimus Isomer C (>60%, contains everolimus)
CAS :Produit contrôlé<p>Stability Unstable in solution, revert back to Everolimus<br>Applications Everolimus Isomer C is an isomer of Everolimus (E945400), a derivative of Rapamycin (R124000). Everolimus inhibits cytokine-mediated lymphocyte proliferation.<br>References Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001); Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001); Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002)<br></p>Formule :C53H83NO14Couleur et forme :NeatMasse moléculaire :958.22Chlorpromazine-d6 Hydrochloride
CAS :Produit contrôlé<p>Applications Labelled Chlorpromazine (C424750). Used as an antiemetic; antipsychotic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Anden, N.-E., et al.: Eur. J. Pharmacol., 11, 303 (1970), Curzon, G., et al.: Trends Pharmacol. Sci., 11, 61 (1990),<br></p>Formule :C172H6H13ClN2S·ClHCouleur et forme :White To Light YellowMasse moléculaire :361.36Prochlorperazine Sulfoxide
CAS :Produit contrôlé<p>Applications A metabolite of Prochlorperazine.<br>References Finn, A., et al.: J. Clin. Pharmacol., 45, 1383 (2005),<br></p>Formule :C20H24ClN3OSCouleur et forme :NeatMasse moléculaire :389.943-Bromo-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one
CAS :Formule :C16H11BrN2OCouleur et forme :Light Brown To Dark BrownMasse moléculaire :327.183-Amino-5-chloro Salicylic Acid Methyl Ester
CAS :<p>Applications Intermediate in the preparation of Azasetron.<br>References Kawakita, T., et al.: Chem. Pharm. Bull., 40, 624 (1992),<br></p>Formule :C8H8ClNO3Couleur et forme :NeatMasse moléculaire :201.61Anastrozole Diacid
CAS :Produit contrôlé<p>Impurity Anastrozole Diacid Impurity<br>Applications Anastroloze Diacid is a derivative of Anastrozole (A637425), an aromatase inhibitor. Used as an antineoplastic. Anastrozole Diacid Imp<br>References Plourde, P.V., et al.: Breast Cancer Res. Treat., 30, 103 (1994), Buzdar, A.U., et al.: Cancer, 79, 730 (1997)<br></p>Formule :C17H21N3O4Couleur et forme :WhiteMasse moléculaire :331.372',6'-Dichloroacetanilide
CAS :Produit contrôléFormule :C8H7Cl2NOCouleur et forme :NeatMasse moléculaire :204.05(±)-Epinephrine-2,5,6,α,β,β-d6
CAS :Produit contrôlé<p>Applications (±)-Epinephrine-2,5,6,alpha,beta,beta-d6 (CAS# 1219803-77-6) is a useful isotopically labeled research compound.<br></p>Formule :C92H6H7NO3Couleur et forme :NeatMasse moléculaire :189.244'-Desmethoxy Omeprazole
CAS :Produit contrôlé<p>Applications 4'-Desmethoxy Omeprazole is one of two impurities in the synthesis of Esomeprazole, an anti-ulcerative drug for treatment of acid-related diseases.<br>References Liu, X., et al.: Lat. Am. J. Pharm., 34, 1265-1268 (2015);<br></p>Formule :C16H17N3O2SCouleur et forme :NeatMasse moléculaire :315.39Desmethyl-N-propyl Imiquimod
CAS :Produit contrôlé<p>Applications Desmethyl-N-propyl Imiquimod is a pharmacologically active compound related to Imiquimod (I475000), an immune response modifier. It stimulates the production of Interferon-a.<br>References Megyeri, K., et al.: Mol. Cell Biol., 15, 2207, (1995), Witt, P.L., et al.: Cancer Res., 53, 5176 (1993), Edwards, L., et al.: Arch. Dermatol., 134, 25 (1998); Gerster, J. et al.: J. Med. Chem., 48, 3481 (2005);<br></p>Formule :C13H14N4Couleur et forme :NeatMasse moléculaire :226.284-Chlorophenothiazine
CAS :Produit contrôlé<p>Applications Intermediate in the preparation of Prochlorperazine (P755800) and related compound.<br></p>Formule :C12H8ClNSCouleur et forme :NeatMasse moléculaire :233.72Olanzapine Thiolactam Impurity
CAS :Formule :C17H20N4OSCouleur et forme :Light YellowMasse moléculaire :328.43Oprozomib
CAS :Produit contrôlé<p>Applications Oprozomib is the second class of proteasome inhibitors with higher specificities and reduced toxicities, against head and neck squamous cell carcinoma.<br>References Zang, Y., et al.: Autophagy., 8, 1837 (2012); Zang, Y., et al.: Clin. Cancer. Res., 18, 5639 (2012); Mato, A.R., et al.: Oncologist., 17, 694 (2012); Zhou, H.J., et al.: J. Med. Chem., 52, 3028 (2009);<br></p>Formule :C25H32N4O7SCouleur et forme :NeatMasse moléculaire :532.61Hydroxy Saxagliptin
CAS :Produit contrôlé<p>Applications Hydroxy Saxagliptin is a metabolite of Saxagliptin (S143500).<br>References Patel, C. et al.: J. Clinic. Pharmacol., 50, 1211 (2010); Feng, J., et al.: J. Med. Chem., 50, 2297 (2007),:Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008);<br></p>Formule :C18H25N3O3Couleur et forme :NeatMasse moléculaire :331.413-(Trifluoromethoxy)aniline
CAS :Produit contrôlé<p>Applications 3-(Trifluoromethoxy)aniline is reactant in the synthesis of pyrazolone-quinazolone hybrids as human hydroxyphenylpyruvate dioxygenase inhibitors which is a potential treatment for type I tyrosinemia.<br>References Xu, Y., et. al.: Bioorg. Med. Chem., 22, 5194 (2014)<br></p>Formule :C7H6F3NOCouleur et forme :NeatMasse moléculaire :177.121-(3,4-Dimethylphenyl)ethanol
CAS :Produit contrôlé<p>Applications 1-(3,4-Dimethylphenyl)ethanol is an intermediate in the production of Medetomidine (M203250), α2-Adrenergic agonist. Sedative; analgesic.<br>References Kagechika, H., et al.: J. Med. Chem., 32, 1098 (1989), ; Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987),<br></p>Formule :C10H14OCouleur et forme :NeatMasse moléculaire :150.22Tavaborole (>90%)
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Tavaborole is a topical treatment of toenail onychomycosis.<br>References Toledo-Bahena, M.E. et. al.: J. Drugs Dermatol., 13, 1124 (2014)<br></p>Formule :C7H6BFO2Degré de pureté :>90%Couleur et forme :NeatMasse moléculaire :151.93(S)-5-Chloro-a-(cyclopropylethynyl)-2-[[(4-methoxyphenyl)methyl]amino]-a-(trifluoromethyl)benzenemethanol
CAS :Produit contrôlé<p>Applications (S)-5-Chloro-α-(cyclopropylethynyl)-2-[[(4-methoxyphenyl)methyl]amino]-α-(trifluoromethyl)benzenemethanol is the S enantiomer of rac-5-Chloro-α-(cyclopropylethynyl)-2-[[(4-methoxyphenyl)methyl]amino]-α-(trifluoromethyl)benzenemethanol (C365145). (S)-5-Chloro-α-(cyclopropylethynyl)-2-[[(4-methoxyphenyl)methyl]amino]-α-(trifluoromethyl)benzenemethanol is also an impurity of Efavirenz (E425000), an HIV-1 reverse transcriptase inhibitor.<br>References Pierce, M., et al.: J. Org. Chem., 63, 8536 (1998)<br></p>Formule :C21H19ClF3NO2Couleur et forme :NeatMasse moléculaire :409.834'-Nitro-3'-(trifluoromethyl)acetanilide
CAS :<p>Applications 4’-Nitro-3’-(trifluoromethyl)acetanilide is a metabolite of the nonsteroidal antiandrogen drug, Flutamide (F598850).<br>References Kang, P. et al.: Drug Metab. Dispos., 36, 1425 (2008); Takashima, E. et al.: Biol. Pharmac. Bull., 26, 1455 (2003); Katchen, B. et al.: J. Invest. Dermatol., 66, 379 (1976);<br></p>Formule :C9H7F3N2O3Couleur et forme :NeatMasse moléculaire :248.16Benzoin
CAS :Produit contrôlé<p>Applications Benzoin has been used as a catalyst in photoinitiation.<br>References Voll, D., et. al.: Macromolecules, 44, 2542 (2011)<br></p>Formule :C14H12O2Couleur et forme :Off-WhiteMasse moléculaire :212.24Haloperidol Octanoate
CAS :Produit contrôléFormule :C29H37ClFNO3Couleur et forme :NeatMasse moléculaire :502.065-(4'-Methyl-2-biphenyl)tetrazole-d4
CAS :Produit contrôlé<p>Applications Labelled Valsartan (V095750) impurity.<br>References Thai, H., et al.: J. Cardiovasc. Pharmacol., 50, 703 (2007), Lukas, J., et al.: Science, 313, 662 (2006),<br></p>Formule :C14H8D4N4Couleur et forme :Off-WhiteMasse moléculaire :240.301Methyl 4-Hydroxy-2-methyl-2H-Thieno[2,3-e]-1,2-thiazine-3-carboxylic Acid 1,1-Dioxide Ester
CAS :Formule :C9H9NO5S2Couleur et forme :NeatMasse moléculaire :275.30rac Viloxazine Hydrochloride
CAS :Produit contrôléFormule :C13H19NO3·ClHCouleur et forme :WhiteMasse moléculaire :273.76N-Nitroso Cyamemazine Impurity
Produit contrôléFormule :C18H18N4OSCouleur et forme :NeatMasse moléculaire :338.427Tianeptine Metabolite MC5-d4 Sodium Salt
CAS :Produit contrôlé<p>Applications Labelled, primary metabolite of Tianeptine.<br>References Dresse, A., et al.: J. Clin. Pharmacol., 28, 1115 (1988), Grislain, L., et al.: Drug Metab. Dispos., 18, 804 (1990),<br></p>Formule :C19H16D4ClN2NaO4SCouleur et forme :NeatMasse moléculaire :434.91Dimethylamine (40% aq.)
CAS :Produit contrôlé<p>Applications Dimethylamine (40% aq.) is a compound often used in industry as a precursor to Nitrosodimethylamine (N525625), a potent carcinogen that is produced during disinfection of wastewater effluent, and is also present in trace amounts in food and polluted air. Dimethylamine is also present in human urine and can be indicative of certain disorders.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gereke, A. & Sedlak, D.: Env. Sci. Tech., 37, 1331 (2003); Mitch, W., et al.: Env. Eng. Sci., 20, 389 (2003); Tsikas, D., et al.: J. Chromatogr. B, 851, 229 (2007)<br></p>Formule :C2H7NCouleur et forme :NeatMasse moléculaire :45.08Tofogliflozin
CAS :Produit contrôlé<p>Applications A novel, potent, and highly selective SGLT2 inhibitor that has been shown to improve glycemic control in diabetic mice and rats.<br></p>Formule :C22H26O6Couleur et forme :NeatMasse moléculaire :386.444-Desfluoro-2-Fluoro Droperidol
CAS :<p>Applications 4-Desfluoro-2-Fluoro Droperidol is an impurity of Droperidol (D679500), a D1, D2 dopamine receptor antagonist; butyrophenone antipsychotic and anti-emetic.<br>References Yelnosky, J., et al.: Toxicol. Appl. Pharmacol., 6, 37 (1964), Janicki, C.A., et al.: Anal. Profiles Drug Subs., 7, 171 (1978), Hamik, et al.: Cancer Chemother. Pharmacol., 24, 307 (1989), Heyer, E.J., et al.: Brain Res., 863, 20 (2000),<br></p>Formule :C22H22FN3O2Couleur et forme :NeatMasse moléculaire :379.4274N-(3-Chloro-6,11-dihydro-6-methyl-5,5-dioxidodibenzo[c,f][1,2]thiazepin-11-yl)-β-alanine-d4
CAS :Produit contrôléFormule :C17H13D4ClN2O4SCouleur et forme :NeatMasse moléculaire :384.87Methyl 4-Methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]benzoate
CAS :Produit contrôlé<p>Applications Methyl 4-methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]benzoate is an intermediate used in the synthesis of 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide (M326838), which is an impurity of Nilotinib (N465300), a possible agent in the treatment of chronic myelogenous leukemia.<br>References Corbin, A., et al.: J. Biol. Chem., 277, 32214 (2002); Golemovic, M., et al.: Clin. Cancer Res., 11, 4941 (2005); Gleixner, K., et al.: Blood, 107, 752 (2006); Nicolini, F., et al.: Leukemia, 20, 1061 (2006)<br></p>Formule :C18H16N4O2Couleur et forme :NeatMasse moléculaire :320.35(Z)-4-(2,4-Difluorobenzoyl)piperidine Oxime
CAS :Produit contrôlé<p>Applications Intermediate in the preparation of Risperidone (R525000) and it’s derivatives.<br></p>Formule :C12H14F2N2OCouleur et forme :NeatMasse moléculaire :240.24924-(4-Amino-1-oxoisoindolin-2-yl)-4-carbamoyl Butyric Acid
CAS :Produit contrôléFormule :C13H15N3O4Couleur et forme :Off WhiteMasse moléculaire :277.28Nintedanib Acetyl Impurity
CAS :Produit contrôlé<p>Applications An impurity of Nintedanib, which is an antifibrotic drug.<br>References Holdsworth, G.; et al.: Scientific Reports, 7, 1 (2017)<br></p>Formule :C26H23N3O4Couleur et forme :NeatMasse moléculaire :441.49Olopatadine-d6
CAS :Produit contrôléFormule :C21H17D6NO3Couleur et forme :NeatMasse moléculaire :343.461H-1-Ethyl-d5 Candesartan
CAS :Produit contrôlé<p>Applications Labelled Candesartan (C175575) impurity.<br></p>Formule :C26H19D5N6O3Couleur et forme :Off-White To Light YellowMasse moléculaire :473.543-Hydroxy-1-methyl-1-Azoniabicyclo[2.2.2]octane Bromide
CAS :Produit contrôlé<p>Applications 3-Hydroxy-1-methyl-1-Azoniabicyclo[2.2.2]octane is an impurity in the synthesis of Clidinium Bromide (C576250), an anticholinergic. Used as an antispasmodic.<br>References Zhang, L., et al.: Pharm. Res., 25, 1902 (2008), Sanderson, H., et al.: Toxicol Lett., 187, 84 (2009),<br></p>Formule :C8H16BrNOCouleur et forme :NeatMasse moléculaire :222.12Thiorphan Disulfide
CAS :Produit contrôlé<p>Applications Thiorphan Disulfide is an impurity of Racecadotril (R070600); an antidiarrheal and enkephalinase inhibitor that reduces the amount of water and electrolytes into the intestine.<br>References Cezard, J., et al.: Gastroenterol., 120, 799 (2001); Sato, T., et al.: J. Med. Chem., 51, 7705 (2008); Lakshmana, P., et al.: J. Pharm. Res., 8, 39 (2009); Fournie-Zaluski<br></p>Formule :C24H28N2O6S2Couleur et forme :NeatMasse moléculaire :504.62(S)-α-Hydroxy-β-methoxy-β-phenyl-benzenepropanoic Acid Methyl Ester
CAS :Produit contrôlé<p>Impurity Ambrisentan Hydroxyester Impurity<br>Applications (S)-α-Hydroxy-β-methoxy-β-phenyl-benzenepropanoic Acid Methyl Ester is an impurity in the synthesis of Ambrisentan (A575860), a nonpeptide endothelin ETA receptor antagonist. Antihypertensive. (Ambrisentan Hydroxyester Impurity)<br>References Riechers, H., et al.: J. Med. Chem., 39, 2123 (1996), Billman, G.E., et al.: Curr. Opin. Invest. Drugs, 3, 1483 (2002), Vatter, H., et al.: Clin. Neuropharmacol., 26, 73 (2003),<br></p>Formule :C17H18O4Couleur et forme :NeatMasse moléculaire :286.32(S)-(-)-Tolvaptan
CAS :Produit contrôlé<p>Applications An enantiomer of Tolvaptan. It is a selective, competitive arginine vasopressin V2 receptor antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).<br>References Paterna, S., et al.: Eur. J. Heart Fail, 2, 305 (2000), Udelson, J., et al.: Circulation, 104, 2417 (2001), Goldsmith, S., et al.: J. Am. Coll Cardiol., 46, 1785 (2005), Schrier, R., et al.: N. Engl. J. Med., 355, 2099 (2006),<br></p>Formule :C26H25ClN2O3Couleur et forme :Off White SolidMasse moléculaire :448.94Loxapine, Succinate
CAS :Produit contrôlé<p>Applications A D2/D4-Dopamine receptor antagonist. A serotonergic receptor antagonist. A dibenzoxazepine antipsychotic agent.<br>References Shen, Y., et al.: J. Biol. Chem., 268, 18200 (1993), Fiorella, D., et al.: Psychopharmacology, 121, 347 (1995), Glusa, E., et al.: Br. J. Pharmacol., 130, 692 (2000)<br></p>Formule :C18H18ClN3O·C4H6O4Couleur et forme :WhiteMasse moléculaire :445.90Hydroxy Celecoxib
CAS :Produit contrôlé<p>Applications A metabolite of Celecoxib (C251000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Penning, T., et al.: J. Med. Chem., 40, 1347 (1997), Paulson, S., et al.: Drug Metab. Dispos., 28, 308 (2000), Kirchheiner, J., et al.: Clin. Pharmacol. Ther., 71, 286 (2002),<br></p>Formule :C17H14F3N3O3SCouleur et forme :NeatMasse moléculaire :397.374-Ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydro-imidazo[5,1-f][1,2,4]-triazin-2-yl)benzene-sulfonyl Chloride
CAS :Produit contrôlé<p>Applications Vardenafil Intermediate.<br>References Terrett, N.K., et al.: Bioorg. Med. Chem. Lett., 6, 1819, (1996)<br></p>Formule :C17H19ClN4O4SCouleur et forme :NeatMasse moléculaire :410.884,5-Dehydro Apixaban
CAS :Produit contrôlé<p>Applications 4,5-Dehydro Apixaban is an impurity of Apixaban (A726700), a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation<br>References Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011)<br></p>Formule :C25H23N5O4Couleur et forme :NeatMasse moléculaire :457.48N-Nitroso Amodiaquine-D10
Produit contrôléFormule :C20D10H11ClN4O2Couleur et forme :NeatMasse moléculaire :394.921Nitroso Norquetiapine-d8
Produit contrôléFormule :C17D8H8N4OSCouleur et forme :NeatMasse moléculaire :348.449Levofloxacin Hydrochloride
CAS :Formule :C18H20FN3O4·(HCl)Couleur et forme :White To Light BeigeMasse moléculaire :361.37 + (36.46)Desmethyl Nintedanib Carboxylic Acid (Nintedanib Impurity A)
Produit contrôlé<p>Applications Desmethyl Nintedanib Carboxylic Acid is an impurity of Intedanib (I666650), which is an indolinone derivative potently blocking VEGF-, PDGF-, and FGF-receptor kinases. it is an indolinone as triple angiokinase inhibitors and an antitumor agent.<br>References Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)<br></p>Formule :C29H29N5O5Couleur et forme :NeatMasse moléculaire :527.57N,O-Diacetyl Pseudoephedrine
CAS :Produit contrôlé<p>Applications N,O-Diacetyl Pseudoephedrine is the diacetylated analogue of the non-selective adrenergic agonist Pseudoephedrine (P839350).<br></p>Formule :C14H19NO3Couleur et forme :NeatMasse moléculaire :249.314,6-Dichloro-2-(propylthio)pyrimidin-5-amine
CAS :Produit contrôlé<p>Applications Intermediate in the preparation of Ticagrelor (T437700) and reversible P2Y12 receptor antagonists.<br>References Zhang, H. et al.; Bioorg. Med. Chem. Lett. 22, 3598 (2012); Springthorpe, B. et al.; Bioorg. Med. Chem. Lett. 17, 6013 (2007)<br></p>Formule :C7H9Cl2N3SCouleur et forme :NeatMasse moléculaire :238.14(1R,3R)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carbo
CAS :Produit contrôlé<p>Applications (1R,3R)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Hydrochloride is an impurity of Tadalafil (T004500) and is a β-carboline derivative. (1R,3R)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Hydrochloride can be used to produce Tadalafil.<br>References Lek Pharmaceuticals d.d., Slovenia: Eur. Pat. Appl., EP 2107059 A1 20091007 (2009)<br></p>Formule :C19H16N2O4·HClCouleur et forme :Off White SolidMasse moléculaire :372.8rac Methotrimeprazine Sulfoxide
CAS :Produit contrôlé<p>Applications A metabolite of Methotrimeprazine (M260785).<br>References Haddad, P., et al.: Drugs, 62, 1649 (2002),<br></p>Formule :C19H24N2O2SCouleur et forme :NeatMasse moléculaire :344.47Rivaroxaban N-Hydrolyse N-5-Chlorothiophene-2-carbaldehyde
CAS :<p>Stability Hygroscopic<br>Applications Rivaroxaban N-Hydrolyse N-5-Chlorothiophene-2-carbaldehyde is an intermediate in synthesizing Rivaroxaban Pseudodimer (R538015), which is an impurity of Rivaroxaban (R538000), a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ansell, J., et al.: Drugs, 64, 1 (2004); Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005); Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005)<br></p>Formule :C24H21Cl2N3O7S2Couleur et forme :NeatMasse moléculaire :598.48S-(s)-Verapamil-D6
CAS :Produit contrôlé<p>Applications Labelled S-Verapamil (V124991). Both isomers inhibit the p-glycoprotein efflux pump in multidrug resistant tumor cells.<br>References Peroutka, S., et al.: J. Ann. Neurol, 23, 500 (1988), Eliason, J.F., et al.: Int. J. Cancer, 46, 113 (1990),<br></p>Formule :C27H33D6ClN2O4Couleur et forme :NeatMasse moléculaire :497.1(6S)-N6-[3-[[(6S)-2-Amino-4,5,6,7-tetrahydro-6-benzothiazolyl]amino]-1-ethyl-2-methylpropyl]-4,5,6,7-tetrahydro-2,6-benzothiazolediamine
CAS :<p>Stability Hygroscopic<br>Applications (6S)-N6-[3-[[(6S)-2-Amino-4,5,6,7-tetrahydro-6-benzothiazolyl]amino]-1-ethyl-2-methylpropyl]-4,5,6,7-tetrahydro-2,6-benzothiazolediamine can be obtained from (-)-2-Amino-6-propionamido-tetrahydrobenzothiazole (A628150) and is the byproduct of process for the preparation of pramipexole and salts thereof by reductive amination of (diamino)tetrahydrobenzothiazole with propanal. It is also a Pramaxo Impurity C.<br>References Deo, K., et al.: Indian Pat. Appl. (2015), IN 2013MU02843 A<br></p>Formule :C20H32N6S2Degré de pureté :>80%Couleur et forme :NeatMasse moléculaire :420.63836a-Naloxol
CAS :Produit contrôlé<p>Applications 6α-Naloxol is a metabolite of Naloxone (N285000), a specific opioid antagonist. Narcotic antagonist.<br>References Chatterjie, N., et al.: J. Med. Chem., 18, 490 (1975); Bilsky, E., et al.: J. Pharmacol. Exp. Ther., 277, 484 (1996); Blokhina, E., et al.: Eur. J, Pharmacol., 406, 227 (2000); Jasinski, D.R., et al.: J. Pharmacol. Exp. Ther., 157, 420 (1967); McNicholas, L.F., et al.: Drugs, 27, 81 (1984); Hasson, M.M.A., et al.: Anal. Profiles Drug Subs., 14, 453 (1985); Stowe, C., et al.: Ann. Pharmacother., 27, 447 (1993)<br></p>Formule :C19H23NO4Couleur et forme :NeatMasse moléculaire :329.39Dehydro Silodosin
CAS :Produit contrôlé<p>Applications Dehydro Silodosin is an impurity of Silodosin (S465000).<br>References Moriyama., et al.: Eur. J. Pharmacol., 331, 39 (1997), Zhu, J., et al.: Br. J. Pharmacol., 131, 546 (2000),<br></p>Formule :C25H30F3N3O4Couleur et forme :NeatMasse moléculaire :493.52rac N-Nitroso-N-Desmethyl Dapoxetine-D3
Produit contrôléFormule :C20D3H17N2O2Couleur et forme :NeatMasse moléculaire :323.4044-Chloro Perphenazine
CAS :Produit contrôlé<p>Applications 4-Chloro Perphenazine is an impurity of Perphenazine (P291100), an D2 dopamine receptor antagonist; α-adrenergic receptor antagonist and σ-receptor agonist; phenothiazine antipsychotic.<br>References Briggs, K., et al.: Toxicology, 231, 113 (2007), Toga, T., et al.: J. Pharmacol. Sci., 105, 207 (2007),<br></p>Formule :C21H26ClN3OSCouleur et forme :NeatMasse moléculaire :403.975-Chloro-N-methylthiophene-2-carboxamide
CAS :Produit contrôlé<p>Applications 5-Chloro-N-methylthiophene-2-carboxamide is an impurity of Rivaroxaban (R538000), which is a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.<br>References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),<br></p>Formule :C6H6ClNOSCouleur et forme :NeatMasse moléculaire :175.64Ambrisentan-d10
CAS :Produit contrôlé<p>Applications Ambrisentan-d10, is the labeled analogue of Ambrisentan (A575860), a nonpeptide endothelin ETA receptor antagonist. Antihypertensive.<br>References Riechers, H., et al.: J. Med. Chem., 39, 2123 (1996), Billman, G.E., et al.: Curr. Opin. Invest. Drugs, 3, 1483 (2002), Vatter, H., et al.: Clin. Neuropharmacol., 26, 73 (2003),<br></p>Formule :C22H12D10N2O4Couleur et forme :NeatMasse moléculaire :388.48
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