Dérivés de Quinazoline et de Quinoléine
Les quinazolines et les quinoléines sont des composés hétérocycliques azotés à structure aromatique qui jouent un rôle clé dans la synthèse de médicaments à activité anticancéreuse, antimicrobienne et anti-inflammatoire. Leurs dérivés présentent des modifications structurelles qui optimisent leur biodisponibilité et leur sélectivité, permettant ainsi le développement de nouveaux principes actifs pour diverses applications thérapeutiques. Ces composés sont utilisés dans la fabrication d’API destinés au traitement du cancer, des infections, des maladies neurodégénératives et cardiovasculaires. De plus, les dérivés de quinazoline et de quinoléine sont essentiels dans la recherche d’inhibiteurs enzymatiques et dans la conception de molécules bioactives innovantes.
Chez CymitQuimica, nous proposons des dérivés de quinazoline et de quinoléine de haute pureté pour des applications en synthèse chimique, développement pharmaceutique et biotechnologie.
65576 produits trouvés pour "Dérivés de Quinazoline et de Quinoléine"
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Ritodrine
CAS :<p>Ritodrine (DU21220) is a β-adrenergic agonist as well as an effective uterine relaxant that can be used in arrest premature labor research[1] [2].</p>Formule :C17H21NO3Couleur et forme :SolidMasse moléculaire :287.35Mefenidil
CAS :<p>Mefenidil (McN-2378), a selective cerebral vasodilator, was shown to increase CBF in healthy brains without stimulating O2 uptake in a dog anesthesia model.</p>Formule :C12H11N3Degré de pureté :98.27%Couleur et forme :SolidMasse moléculaire :197.24AZD-1656
CAS :<p>AZD-1656 is a glucokinase activator (GKA) that can cause dose-limiting hypoglycemia in normal animals used in embryofetal development studies and type 2</p>Formule :C24H26N6O5Degré de pureté :97.07% - 99.37%Couleur et forme :SolidMasse moléculaire :478.5Brasofensine
CAS :<p>Brasofensine, a benztoalkane MA reuptake inhibitor, shows promise for Parkinson's and Alzheimer's.</p>Formule :C16H20Cl2N2OCouleur et forme :SolidMasse moléculaire :327.25Bufuralol
CAS :<p>Bufuralol (Ro 3-4787) is a 尾-adrenergic receptor blocker with a certain degree of sympathomimetic effects and can be used to study cardiovascular diseases.</p>Formule :C16H23NO2Degré de pureté :98.26%Couleur et forme :SolidMasse moléculaire :261.36Celiprolol hydrochloride
CAS :Celiprolol hydrochloride (Selectrol) is a cardioselective beta-1 adrenergic antagonist that has intrinsic sympathomimetic activity.Formule :C20H33N3O4·HClCouleur et forme :White Crystalline SolidMasse moléculaire :415.96Apratastat
CAS :<p>Apratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-α converting enzyme (TACE) and matrix metalloproteinases (MMPs)</p>Formule :C17H22N2O6S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :414.5ONO 4817
CAS :<p>ONO-4817 suppresses MMPs, limiting plaque progression and aortic hyperplasia in hyperlipidemic rabbits.</p>Formule :C22H28N2O6Couleur et forme :SolidMasse moléculaire :416.47ROCK2-IN-7
CAS :<p>ROCK2 inhibitor is a chemical compound associated with the therapeutic management of psoriasis.</p>Formule :C26H28FN5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :445.53KB-R7785
CAS :<p>KB-R7785 is a novel ADAM12/MMP inhibitor improving heart function and insulin sensitivity by blocking HB-EGF and TNF-alpha.</p>Formule :C18H27N3O4Couleur et forme :SolidMasse moléculaire :349.42XL-784
CAS :<p>XL-784 is a selective MMP inhibitor with low IC50s for MMP-1,2,3,8,9,13, modulating extracellular matrix remodeling, tumor invasion, and metastasis in cancer.</p>Formule :C42H42Cl2F4MgN6O16S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1122.15RU 58668
CAS :<p>Pure antiestrogen that downregulates estrogen receptor expression</p>Formule :C34H43F5O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :658.76LX7101
CAS :<p>LX7101 is an effective inhibitor of LIMK and ROCK2 (IC50: 24, 1.6, and 10 nM for LIMK1, LIMK2, and ROCK2, respectively). It also inhibits PKA (IC50 <1 nM).</p>Formule :C23H29N7O3Degré de pureté :99.08%Couleur et forme :SolidMasse moléculaire :451.52(Rac)-Lonafarnib
CAS :<p>(Rac)-Lonafarnib is a racemic FTase inhibitor, effective against H-ras, K-ras, N-ras (IC50: 1.9, 5.2, 2.8 nM), and has anti-HDV properties.</p>Formule :C27H31Br2ClN4O2Couleur et forme :SolidMasse moléculaire :638.82Bufuralol (hydrochloride)
CAS :<p>Bufuralol hydrochloride is a potent, non-selective, orally active β-blocker with partial agonist effects and a CYP2D6 probe.</p>Formule :C16H24ClNO2Couleur et forme :SolidMasse moléculaire :297.82MMP13-IN-3
CAS :<p>MMP13-IN-3 is an oral, selective MMP-13 inhibitor with IC50 of 1 nM, >1000x selective, for osteoarthritis treatment.</p>Formule :C24H22N4O5Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :446.46Gepirone
CAS :<p>Gepirone is a 5-HT1A receptor agonist belonging to the buspirone family. Gepirone HCl possesses greater selectivity for the 5-HT1A receptor than SSRIs.</p>Formule :C19H29N5O2Degré de pureté :99.35% - 99.89%Couleur et forme :SolidMasse moléculaire :359.47FGIN-1-27
CAS :<p>FGIN-1-27 is a high-affinity agonist of the translocator protein and a specific peripheral benzodiazepine receptor (PBR) ligand(Ki = 5.0 nM).</p>Formule :C28H37FN2ODegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :436.6Quizalofop
CAS :<p>Quizalofop (Xylafop) is a reagent of biochemical.</p>Formule :C17H13ClN2O4Degré de pureté :97.14%Couleur et forme :SolidMasse moléculaire :344.75Yonkenafil
CAS :<p>Yonkenafil, a PDE5 inhibitor, may reduce stroke damage and aid in Alzheimer's treatment.</p>Formule :C24H33N5O4SCouleur et forme :SolidMasse moléculaire :487.61MMP-7-IN-2
CAS :<p>MMP-7-IN-2 acts as a selective and potent MMP7 inhibitor and can be used to study inflammatory responses and vascular-related diseases.</p>Formule :C28H40ClF3N6O9SDegré de pureté :97.82%Couleur et forme :SolidMasse moléculaire :729.17XL-784 free base
CAS :<p>XL-784 free base selectively inhibits MMPs with IC50: MMP-1 (1.9µM), MMP-2 (0.81nM), MMP-3 (120nM), MMP-8 (10.8nM), MMP-9 (18nM), MMP-13 (0.56nM).</p>Formule :C21H22ClF2N3O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :549.93Collagen proline hydroxylase inhibitor
CAS :<p>Collagen proline hydroxylase inhibitor is an inhibitor collagen proline hydroxylase and useful for antifibrotic proliferative agents.</p>Formule :C18H18N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :354.36Etidocaine Hydrochloride
CAS :<p>Etidocaine Hydrochloride (W19053) is a long-acting anesthetic and a blocker of the voltage-gated sodium channel.</p>Formule :C17H29ClN2ODegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :312.88LY52
CAS :<p>LY52 is a matrix metalloproteinase-2 inhibitor. It acts by suppressing tumor invasion and metastasis.</p>Formule :C22H24N4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :440.45ND-378
CAS :<p>ND-378 is a potent and selective inhibitor of MMP-2 with no inhibition on MMP-9 and MMP-14.</p>Formule :C18H19NO4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :377.48TP0556351
CAS :<p>TP0556351: potent MMP2 inhibitor with 0.2 nM IC50, reduces collagen in pulmonary fibrosis mice.</p>Formule :C50H70N10O16Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1067.15Z-PDLDA-NHOH
CAS :<p>Z-PDLDA-NHOH is a potent, specific vertebrate collagenase inhibitor [1].</p>Formule :C22H32N4O6Couleur et forme :SolidMasse moléculaire :448.51Dothiepin
CAS :<p>Dothiepin (Dosulepin; Dothep), an antidepressant with sedative/anxiolytic properties, preferentially inhibits noradrenaline over serotonin uptake, enhancing</p>Formule :C19H21NSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :295.44ICI 204448
CAS :<p>ICI 204448 is a potent and peripherally selective κ-opioid agonist.</p>Formule :C23H26Cl2N2O4Couleur et forme :SolidMasse moléculaire :465.37Ro 32-7315
CAS :<p>Ro 32-7315 is a selective inhibitor of ADAM17.</p>Formule :C22H35N3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :453.6Naxagolide free base
CAS :<p>Naxagolide is a sustained release formulation. It is a dopamine agonist.</p>Formule :C15H21NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :247.33Ubrogepant
CAS :<p>Ubrogepant (MK-1602) is an antagonist of calcitonin gene-related peptide receptor that can be used in the acute treatment of migraine studies.</p>Formule :C29H26F3N5O3Degré de pureté :99.452% - 99.78%Couleur et forme :SolidMasse moléculaire :549.54Inz-1
CAS :<p>Inz-1 is an effective and fungal-selective inhibitor of mitochondrial cytochrome bc1 with IC50s of 8.092 and 45.320 μM for yeast and human.</p>Formule :C16H14N2O2Degré de pureté :99.55% - 99.88%Couleur et forme :SolidMasse moléculaire :266.29Ro 31-9790
CAS :<p>Ro 31-9790 is a synthetic inhibitor of metalloproteinase (MMP).</p>Formule :C15H29N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :315.41Frovatriptan
CAS :<p>Frovatriptan, potent 5-HT 1B/D agonist, shows high cerebroselectivity and efficacy for migraine with aura.</p>Formule :C14H17N3OCouleur et forme :SolidMasse moléculaire :243.3Brilaroxazine
CAS :<p>Brilaroxazine (RP5063): multimodal dopamine/5-HT modulator, partial agonist at D2/D3/D4, 5-HT1A/2A, and antagonist at 5-HT2B/7.</p>Formule :C22H25Cl2N3O3Degré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :450.36Sitagliptin impurity E
CAS :<p>Sitagliptin impurity E is an inhibitor of dipeptidyl peptidase-4 (DPP-IV) that is used as a hypoglycemic agent. Sitagliptin impurity E has been shown to increase the glucose-lowering effect in diabetic patients with type 2 diabetes mellitus. It is also effective in reducing postprandial glucose and insulin levels. Sitagliptin impurity E has been shown to increase the concentration of insulin in plasma for up to 24 hours after administration, which suggests that it may be useful for the treatment of metabolic disorders such as obesity and type 2 diabetes mellitus.</p>Formule :C16H15F6N5ODegré de pureté :Min. 95%Masse moléculaire :407.31 g/mol4-[(2RS)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-benzaldehyde hydrochloride
CAS :<p>4-[(2RS)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-benzaldehyde hydrochloride is a drug product. It is used as an analytical standard and in the development of drugs. The metabolite of 4-[(2RS)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-benzaldehyde hydrochloride, 4-[(2RS)-2-hydroxy-3-[(1-methylethyl)amino]propoxy]-N-(4-nitrophenyl)benzamide, has been shown to inhibit the production of cytokines IL6 and TNFα by human monocytes, macrophages, and dendritic cells. Metabolism studies have shown that 4-[(2RS)-2-hydroxy-3-[(1-methylethyl)amino]propoxy]-N</p>Formule :C13H20ClNO3Degré de pureté :Min. 95%Masse moléculaire :273.76 g/mol1-(6-Chloro-9H-carbazol-2-yl)ethanone
CAS :<p>1-(6-Chloro-9H-carbazol-2-yl)ethanone is a chemical substance that belongs to the class of synthetic drugs. It is used as a pharmaceutical intermediate in the production of other chemical substances, including antibiotics and antihypertensives. 1-(6-Chloro-9H-carbazol-2-yl)ethanone has been shown to be metabolized by cytochrome P450 enzymes and by glucuronidases or esterases. This product can also be used as an impurity standard for HPLC analyses of fluoroquinolones.</p>Formule :C14H10ClNODegré de pureté :Min. 95%Masse moléculaire :243.69 g/mol7'-Methyl-2'-propyl-2,5'-bi-1H-benzimidazole
CAS :<p>7'-Methyl-2'-propyl-2,5'-bi-1H-benzimidazole (7'-MPB) is a benzimidazole derivative that is used as a medicine. It is made from recycled chemicals and has shown to have industrial applications as a catalyst for cyclization reactions. 7'-MPB is also used in the production of benzenesulfonic acid, which is an organic solvent. This chemical has been shown to be effective against high blood pressure, but has not been tested on humans yet. Telmisartan, which belongs to the angiotensin II receptor blocker class of drugs, can inhibit the synthesis of prostaglandins.</p>Formule :C18H18N4Degré de pureté :Min. 95%Masse moléculaire :290.36 g/molCollagen proline hydroxylase inhibitor-1
CAS :<p>Collagen proline hydroxylase inhibitor-1 具有抗纤维增生活性。</p>Formule :C24H21N5O4Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :443.45Elobixibat
CAS :<p>Elobixibat (A 3309) blocks IBAT in mice/humans/dogs (IC50: 0.13/0.53/5.8 nM); used for constipation research.</p>Formule :C36H45N3O7S2Degré de pureté :97.43% - 98.03%Couleur et forme :SolidMasse moléculaire :695.89Maralixibat Chloride
CAS :<p>Maralixibat Chloride (LUM001 chloride), an apical, sodium-dependent, bile acid transport inhibitor, prevents enterohepatic bile acid recirculation.</p>Formule :C40H56ClN3O4SDegré de pureté :99.19% - 99.65%Couleur et forme :SolidMasse moléculaire :710.41Aderamastat
CAS :<p>Aderamastat (FP-025) is an orally active matrix metalloproteinase 12 (MMP-12) inhibitor indicated for the study of allergic asthma, COPD and pulmonary fibrosis.</p>Formule :C21H18N2O4SDegré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :394.44Lumateperone
CAS :<p>Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).</p>Formule :C24H28FN3ODegré de pureté :99.68% - 99.91%Couleur et forme :SolidMasse moléculaire :393.52-Amino-5,6-dichloro-3(4H)-quinazoline acetic acid
CAS :<p>This is a synthetic, impurity standard for 2-Amino-5,6-dichloro-3-(4H)-quinazoline acetic acid (CAS No. 1159977-03-3) that can be used in the drug product development process. This product is available as a custom synthesis and as an analytical standard for HPLC. It is also available as a pharmacopoeia grade material. The compound has been shown to have niche applications in metabolism studies and natural products research.</p>Formule :C10H9Cl2N3O2Degré de pureté :Min. 95%Masse moléculaire :274.1 g/mol11,11'-(1,4-Piperazinediyl)bis-dibenzo[b,f][1,4]thiazepine
CAS :<p>11,11'-(1,4-Piperazinediyl)bis-dibenzo[b,f][1,4]thiazepine is a molecule that inhibits the replication of DNA and RNA in viruses. The structure of 11,11'-(1,4-Piperazinediyl)bis-dibenzo[b,f][1,4]thiazepine has been determined by X-ray crystallography. Hepatocyte cells were used for this study because they are important for the metabolism of drugs. This molecule binds to serine proteases and prevents them from functioning properly. It also inhibits the replication of hepatitis C virus and human immunodeficiency virus type 1 (HIV-1). 11,11'-(1,4-Piperazinediyl)bis-dibenzo[b,f][1,4]thiazepine can be used as a template for designing other molecules with antiviral</p>Formule :C30H24N4S2Degré de pureté :Min. 95%Couleur et forme :Yellow SolidMasse moléculaire :504.67 g/molRuDiOBn
CAS :<p>RuDiOBn exhibits low antioxidant activity by scavenging DPPH and ABTS free radicals with scavenging rates of 13.2% and 5.9% at a concentration of 100 μg/mL. It inhibits collagen glycation and reduces the formation of advanced glycation end-products (AGE) with an IC50 of 2.45 μg/mL. RuDiOBn also enhances fibroblast proliferation and migration, stimulates collagen synthesis, and aids in skin repair and regeneration while inhibiting collagenase.</p>Formule :C29H22O7Couleur et forme :SolidMasse moléculaire :482.481Vibegron
CAS :<p>Vibegron (MK-4618) is an effective and selective Beta 3 adrenergic receptor agonist, used to treat overactive bladder (OAB).</p>Formule :C26H28N4O3Couleur et forme :SolidMasse moléculaire :444.53UK-370106
CAS :<p>UK-370106 is a potent and highly selective inhibitor of MMP-3 with IC50 of 23 nM and MMP-12 with IC50 of 42 nM, and potently inhibits cleavage of [3H]-</p>Formule :C35H44N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :572.73Aclidinium
CAS :<p>Aclidinium, a dual-action compound, serves as a long-acting muscarinic antagonist and a β2-adrenoceptor (β2-AR) agonist, exhibiting bronchodilator properties. It effectively reduces lung hyperinflation, enhances lung function, and prolongs exercise endurance time. This compound is commonly utilized in studies focusing on chronic obstructive pulmonary disease (COPD).</p>Formule :C26H30NO4S2Couleur et forme :SolidMasse moléculaire :484.65Finafloxacin
CAS :<p>Finafloxacin is a pH-activated fluoroquinolone, most effective at pH 5.0-6.0, targeting bacterial topoisomerases, used for UTIs and H. pylori infections.</p>Formule :C20H19FN4O4Couleur et forme :SolidMasse moléculaire :398.39COTI-219
CAS :<p>COTI-219 is an oral inhibitor of KRAS with antitumor properties [1].</p>Formule :C17H18N6SCouleur et forme :SolidMasse moléculaire :338.43BAY-7598
CAS :<p>BAY-7598 is a potent, selective, and orally bioavailable MMP12 inhibitor (IC50s: 0.085, 0.67, and 1.1 nM for human/murine/rat MMP12).</p>Formule :C28H31N3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :505.56Arterolane
CAS :<p>Arterolane is an antimalarial compound. For against P. falciparum Ro73 and W2, the IC50s are both 1.1 nM.</p>Formule :C22H36N2O4Couleur et forme :SolidMasse moléculaire :392.533-Aminobenzene-1,2-diol
CAS :<p>3-Aminobenzene-1,2-diol (compound C8) is an inhibitor of matrix metalloproteinases (MMP), with IC50 values of 20, 26, 16, and 16.3 μM against MMP-2, MMP-8, MMP-9, and MMP-14, respectively.</p>Formule :C6H7NO2Couleur et forme :SolidMasse moléculaire :125.13ZK159222
CAS :<p>ZK159222 is an effective 1α,25-(OH)2D3 receptor (VDR) agonist. ZK159222 has a partial agonistic character.</p>Formule :C32H48O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :512.72CM-352
CAS :<p>CM-352 is a metalloproteinase inhibitor that reduces brain damage and improves functional recovery in rat models of cerebral hemorrhage.</p>Formule :C24H29N3O6SDegré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :487.57SD-2590 HCl
CAS :<p>SD-2590 HCl is an MMP-2,-3, -9, -8, 13, and -14 inhibitor.</p>Formule :C22H26ClF3N2O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :554.96SD-7300
CAS :<p>SD-7300 (SC-81490) functions as an orally active inhibitor targeting MMP-2, MMP-9, and MMP-13, exhibiting potent inhibition with K_i values of 0.03, 0.01, and 0.03 nM, respectively. By inhibiting these metalloproteinases, SD-7300 effectively reduces extracellular matrix degradation by tumor cells, thereby curbing their invasion and metastasis. Additionally, this compound acts as a dose-dependent inhibitor of mouse corneal angiogenesis and prevents interleukin-1-induced degradation of bovine cartilage. SD-7300 is applicable in the study of breast cancer.</p>Formule :C21H30F3N3O7SCouleur et forme :SolidMasse moléculaire :525.54UK 356618
CAS :<p>UK 356618 is a potent and selective inhibitor of matrix metalloprotease-3 (IC50: 5.9 nM).</p>Formule :C34H43N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :557.72OncoFAP
CAS :<p>OncoFAP is an ultra-high affinity fibroblast activating protein (FAP) ligand with potential tumour targeting.</p>Formule :C21H19F2N5O5Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :459.40Thioquinapiperifil dihydrochloride
CAS :<p>Thioquinapiperifil dihydrochloride is a potent, selective PDE-5 inhibitor (IC50: 0.074 nM) for research.</p>Formule :C24H29ClN6OSDegré de pureté :98.73%Couleur et forme :SolidMasse moléculaire :485.05Beloranib
CAS :<p>Beloranib is a fumagillin anticancer drug. Beloranib belongs to an angiogenesis inhibitor.</p>Formule :C29H41NO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :499.64Indinavir monohydrate
CAS :<p>Indinavir monohydrate is a potent and specific HIV protease inhibitor that appears to have good oral bioavailability.</p>Formule :C36H49N5O5Couleur et forme :SolidMasse moléculaire :631.82Lisuride
CAS :<p>Lisuride: an oral D2 dopamine agonist, ergot derivative, used in Parkinson's, migraine, and high prolactin research.</p>Formule :C20H26N4OCouleur et forme :SolidMasse moléculaire :338.45Faldaprevir
CAS :<p>Faldaprevir is an orally effective, selective, non-covalent HCV NS3/4A protease inhibitor with high inhibitory activity against HCV 1a and 1b genotype.</p>Formule :C40H49BrN6O9SDegré de pureté :99.04% - 99.19%Couleur et forme :SolidMasse moléculaire :869.82RJF02215
CAS :<p>RJF02215, an MMP-9 inhibitor, exhibits growth inhibitory activity against the ovarian cancer cell line SKOV3. It is utilized in tumor research.</p>Formule :C17H12ClN3OS3Couleur et forme :SolidMasse moléculaire :405.95(3S,4R)-Tofacitinib
CAS :<p>(3S,4R)-Tofacitinib is an less active enantiomer of Tofacitinib. Tofacitinib is a JAK3 inhibitor(IC50 : 1 nM).</p>Formule :C16H20N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :312.37Rodatristat
CAS :<p>Rodatristat is an effective tryptophan hydroxylase 1 and TPH2 inhibitor (IC50s: 33 nM and 7 nM, respectively).</p>Formule :C27H27ClF3N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :561.98PNU-248686A
CAS :<p>PNU-248686A is an inhibitor of matrix metalloproteinase (MMP).</p>Formule :C22H18ClNaO5S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :484.95HU-308
CAS :<p>HU-308, a synthetic cannabinoid analogue, is a highly selective agonist of the CB2 receptor. It demonstrates an affinity for the CB2 receptor that is over 440 times greater than its affinity for the CB1 receptor, which are predominantly found in immune cells. This compound plays a crucial role in modulating the immunosuppressive effects of the endocannabinoid system (ECS). Additionally, HU-308 possesses anti-inflammatory and neuroprotective properties, and it regulates the function of microglia. Its potential applications include research into neuroinflammation and retinal diseases.</p>Formule :C27H42O3Couleur et forme :SolidMasse moléculaire :414.62Tofogliflozin
CAS :<p>Tofogliflozin specifically inhibits SGLT2; IC50s are 2.9 nM (human), 14.9 nM (rat), 6.4 nM (mouse).</p>Formule :C22H26O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :386.44Tipelukast
CAS :<p>Tipelukast (KCA 757), an oral drug for asthma research, blocks leukotrienes and fights inflammation and fibrosis.</p>Formule :C29H38O7SDegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :530.67Quinagolide Free Base
CAS :<p>Quinagolide Free Base is a non-ergot dopamine D(2)-agonist.</p>Formule :C20H33N3O3SCouleur et forme :SolidMasse moléculaire :395.56Macitentan (n-butyl analogue)
CAS :<p>Macitentan n-butyl analogue, an oral ETA/ETB receptor blocker, may treat IPF and PAH.</p>Formule :C20H21Br2N5O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :587.29Tezosentan
CAS :<p>Tezosentan is an antagonist of the endothelin receptor (pA2s: 9.5, 7.7 for ETA and ETB receptors, respectively).</p>Formule :C27H27N9O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :605.63Quinapril
CAS :<p>Quinapril is an orally active, non-peptide, and non-thiol angiotensin-converting enzyme (ACE) inhibitor. It primarily blocks the conversion of angiotensin I to angiotensin II in both plasma and tissues. Upon enzymatic hydrolysis, Quinapril is converted into the pharmacologically active Quinaprilat and is effective in hypertension models.</p>Formule :C25H30N2O5Couleur et forme :SolidMasse moléculaire :438.516Neptinib
CAS :<p>Neptinib (NEP010), a derivative of Afatinib, exhibits enhanced antitumor properties and improved pharmacokinetics when administered orally. It demonstrates a notable suppression of tumor expansion in mouse models of non-small cell lung cancer harboring various EGFR mutations. Furthermore, Neptinib effectively inhibits the EGFR kinase family, exhibiting IC 50 values of 0.24 nM for EGFR wt, 7.25 nM for EGFR L858R/T790M, 0.46 nM for EGFR L858R, and 1.79 nM for EGFR T790M.</p>Formule :C22H23ClFN5O2Couleur et forme :SolidMasse moléculaire :443.90Aleglitazar
CAS :<p>Aleglitazar (R1439) (R1439) is a potent dual PPARα/γ agonist, with IC50s of 38 nM and 19 nM for human PPARa and PPARγ, respectively.</p>Formule :C24H23NO5SDegré de pureté :99.03%Couleur et forme :SolidMasse moléculaire :437.51Vecabrutinib
CAS :<p>Vecabrutinib (SNS-062) is a potent and noncovalent BTK and ITK inhibitor (Kd: 0.3 nM and 2.2 nM, respectively). Vecabrutinib displays an IC50 of 24 nM for ITK.</p>Formule :C22H24ClF4N7O2Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :529.92Obicetrapib
CAS :<p>Obicetrapib (AMG-899) is an inhibitor of cholesteryl ester transfer protein.</p>Formule :C32H31F9N4O5Degré de pureté :99.26% - >99.99%Couleur et forme :SolidMasse moléculaire :722.6(S)-Rasagiline
CAS :<p>(S)-Rasagiline is rasagiline S-isomer, and is an agent of anti-Parkinson.</p>Formule :C12H13NCouleur et forme :SolidMasse moléculaire :171.24Acetyl Rotigotine Hydrochloride ((S)-6-(propyl(2-(thiophen-2-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-yl acetate hydrochloride)
CAS :Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormule :C21H28ClNO2SCouleur et forme :Off-White SolidMasse moléculaire :393.15293Apremilast Related Compound E
CAS :Other aromatic organo-sulfur compounds (excluding pesticides)Formule :C22H24N2O7SCouleur et forme :Pale Yellow PowderMasse moléculaire :460.13042Methylbis(2-pyridylethyl)amine Hydrochloride (N-Methyl-N,N-bis(2-pyridin-2-yl-ethyl)amine trihydrochloride)
CAS :Compounds containing an unfused pyridine ring in the structure, nesoiFormule :C15H19N3·3HClCouleur et forme :Light Brown PowderMasse moléculaire :241.1579Apremilast
CAS :Other aromatic organo-sulfur compounds (excluding pesticides)Formule :C22H24N2O7SMasse moléculaire :460.13042Rivaroxaban Open Ring ((R)-5-chloro-N-(2-hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)thiophene-2-carboxamide)
CAS :Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormule :C18H20ClN3O4SCouleur et forme :Off-White SolidMasse moléculaire :409.0863Chlorothiophene carboxylic acid (5-chlorothiophene-2-carboxylic acid)
CAS :Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormule :C5H3ClO2SCouleur et forme :Off-White Pale Yellow SolidMasse moléculaire :161.95423Levetiracetam acid ((S)-2-(2-oxopyrrolidin-1-yl)butanoic acid)
CAS :<p>Lactams, nesoi</p>Formule :C8H13NO3Couleur et forme :Off-White SolidMasse moléculaire :171.08954Ezetimibe Ketone ((3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)azetidin-2-one)
CAS :Lactams, nesoiFormule :C24H19F2NO3Couleur et forme :White SolidMasse moléculaire :407.1333Ezetimibe Desfluoroaniline Analog ((3R,4S)-3-[(S)-3-(4-Fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one)
CAS :Lactams, nesoiFormule :C24H22FNO3Couleur et forme :White Off-White PowderMasse moléculaire :391.15837Dasatinib
CAS :Compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structureFormule :C22H26ClN7O2S·H2OMasse moléculaire :505.16629Everolimus System Suitability Mixture (This is a mixture of Everolimus, Everolimus oxepane isomer and 9-O-Hydroxyethyl Sirolimus)
Diagnostic or lab reagents on a backing, prepared diagnostic or lab reagents whether or not on a backing, whether or not in the form of kits, nesoiCouleur et forme :White Yellow PowderApremilast R-Enantiomer
CAS :Other aromatic organo-sulfur compounds (excluding pesticides)Formule :C22H24N2O7SCouleur et forme :White Off-White PowderMasse moléculaire :460.13042Ezetimibe Tetrahydropyran Analog ((2R,3R,6S)-N,6-bis(4-fluorophenyl)-2-(4-hydroxyphenyl)tetrahydro-2H-pyran-3-carboxamide)
CAS :Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoiFormule :C24H21F2NO3Couleur et forme :White Off-White SolidMasse moléculaire :409.14895Methoxyamiodarone ([2-[(1RS)-1-Methoxybutyl]benzofuran-3-yl][4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone) (DISCONTINUED)
CAS :Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoiFormule :C26H31I2NO4Couleur et forme :Colorless GelMasse moléculaire :675.03425Desmethoxy Omeprazole (2-(((3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-5-methoxy-1H-benzo[d]imidazole; 2-[(RS)-[(3,5-Dimethylpyridin-2-yl)methyl]sulfinyl]-5-methoxy-1H-benzimidazole) (DISCONTINUED)
CAS :Compounds containing an unfused pyridine ring in the structure, nesoiFormule :C16H17N3O2SCouleur et forme :White Off-White SolidMasse moléculaire :315.10415N-Acetyl-L-Leucine (Acetyl-L-leucine)
CAS :Acyclic amides (including acyclic carbamates) and their derivatives and salts thereof, nesoiFormule :C8H15NO3Couleur et forme :White PowderMasse moléculaire :173.10519Ezetimibe 2-Fluorobenzene Isomer ((3R,4S)-1-(4-fluorophenyl)-3-((S)-3-(2-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one)
CAS :Lactams, nesoiFormule :C24H21F2NO3Couleur et forme :White Off-White SolidMasse moléculaire :409.14895Dasatinib Related Compound A
CAS :Compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structureFormule :C22H26ClN7O3SMasse moléculaire :503.15064(4-Methylbenzoyl)trifluoroacetone (1,1,1-Trifluoro-4-hydroxy-4-(4-methylphenyl)-3-buten-2-one)
CAS :Ketones and quinones, w/not with other oxygen function,and their halogenated,sulfated,nitrated,or nitrosated derivatives, nesoiFormule :C11H9F3O2Couleur et forme :White SolidMasse moléculaire :230.05546Atazanavir Benzylidenehydrazine Carbamate (Methyl [(S)-1-{[(2S,3S)-3-hydroxy-1-phenyl-4-{1-[4-(pyridin-2-yl)benzyl]-2-[4-(pyridin-2-yl)benzylidene]hydrazinyl}butan-2-yl]amino}-3,3-dimethyl-1-oxobutan-2-yl]carbamate)
CAS :Compounds containing an unfused pyridine ring in the structure, nesoiFormule :C42H46N6O4Couleur et forme :Light Yellow SolidMasse moléculaire :698.35805(-)-3,4-Dihydroxynorephedrine
CAS :Formule :C9H13NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :183.2044Azilsartan Impurity 62
CAS :Formule :C14H16O8Couleur et forme :Off-White SolidMasse moléculaire :312.272,2,3,3,5,5,6,6-Octafluoro-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl] Morpholine
CAS :Formule :C7F15NOMasse moléculaire :399.06Metamizole EP Impurity E
CAS :Formule :C12H15N3O4SCouleur et forme :White To Off-White SolidMasse moléculaire :297.331Z,3E,5E,7E-Indocyanine Green Impurity 23 Sodium Salt
Formule :C42H46N2O6S2·NaMasse moléculaire :738.96 22.99Paroxetine Impurity 8
CAS :Formule :C13H18FNOCouleur et forme :Off-White SolidMasse moléculaire :223.29Clonidine Impurity 4 (Ethylenediamine p-toluenesulfonate)
CAS :Formule :C7H8O3S·C2H8N2Couleur et forme :White To Off-White SolidMasse moléculaire :172.20 60.10Cetirizine Glycerol Ester HCl
CAS :Formule :C24H31ClN2O5·HClCouleur et forme :White To Off-White SolidMasse moléculaire :462.97 36.46Etoricoxib Impurity 24
CAS :Formule :C3H4ClNOCouleur et forme :White To Off-White SolidMasse moléculaire :105.52Flupyradifurone-d5 (Major)
CAS :Formule :C12H6D5ClF2N2O2Couleur et forme :White To Off-White SolidMasse moléculaire :293.71MMP13-IN-2
CAS :<p>MMP13-IN-2 is a highly potent, selective, and orally active inhibitor of MMP-13. It demonstrates exceptional potency against MMP-13, with an IC50 value of 0.036 nM, and exhibits selectivities greater than 1,500-fold over MMP-1, 3, 7, 8, 9, 14, and TACE. Moreover, MMP13-IN-2 possesses the capability to effectively inhibit collagen release from cartilage in vitro. Consequently, MMP13-IN-2 holds great potential for advancing research on collagenase-related diseases.</p>Formule :C24H19FN6O4SCouleur et forme :SolidMasse moléculaire :506.51
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