Dérivés de Quinazoline et de Quinoléine
Les quinazolines et les quinoléines sont des composés hétérocycliques azotés à structure aromatique qui jouent un rôle clé dans la synthèse de médicaments à activité anticancéreuse, antimicrobienne et anti-inflammatoire. Leurs dérivés présentent des modifications structurelles qui optimisent leur biodisponibilité et leur sélectivité, permettant ainsi le développement de nouveaux principes actifs pour diverses applications thérapeutiques. Ces composés sont utilisés dans la fabrication d’API destinés au traitement du cancer, des infections, des maladies neurodégénératives et cardiovasculaires. De plus, les dérivés de quinazoline et de quinoléine sont essentiels dans la recherche d’inhibiteurs enzymatiques et dans la conception de molécules bioactives innovantes.
Chez CymitQuimica, nous proposons des dérivés de quinazoline et de quinoléine de haute pureté pour des applications en synthèse chimique, développement pharmaceutique et biotechnologie.
65630 produits trouvés pour "Dérivés de Quinazoline et de Quinoléine"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
Adrafinil, (R)-
CAS :<p>Adrafinil (R)-isomer, former eugeroic for enhancing alertness, attention, and mood in elderly.</p>Formule :C15H15NO3SCouleur et forme :SolidMasse moléculaire :289.35Cibenzoline
CAS :Cibenzoline: antiarrhythmic, blocks KATP channels, minimizes LVPG, useful in hypertrophic cardiomyopathy studies.Formule :C18H18N2Couleur et forme :SolidMasse moléculaire :262.35Azelastine
CAS :<p>Azelastine (Azelastinum) is a phthalazine derivative, and is an histamine antagonist and mast cell stabilizer.</p>Formule :C22H24ClN3ODegré de pureté :99.35%Couleur et forme :White Crystal PowderMasse moléculaire :381.90Bifeprunox
CAS :Bifeprunox: potent antipsychotic, partial agonist at D2-like/5-HT1A receptors; treats schizophrenia.Formule :C24H23N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :385.46Isothipendyl
CAS :Isothipendyl is the first generation of H1 antagonists (antihistamines) and anticholinergics and has an effect on itching.Formule :C16H19N3SCouleur et forme :SolidMasse moléculaire :285.41Blonanserin HCl
CAS :Blonanserin is an antagonist of dopamine-D2 and serotonin-S2.Formule :C23H32Cl2FN3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :440.42Amorolfine
CAS :<p>Amorolfine is available in the nail lacquer and can be used to treat fungal nail infections.</p>Formule :C21H35NOCouleur et forme :White To Off-White Crystalline PowderMasse moléculaire :317.517Famotidine disulfide
CAS :<p>Famotidine disulfide blocks histamine, reduces acid, treats ulcers and GERD.</p>Formule :C10H14N8S4Couleur et forme :SolidMasse moléculaire :374.53(R)-Carvedilol
CAS :(R)-Carvedilol is a non-selective blocker of β/α-1. (R)-Carvedilol exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX).Formule :C24H26N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :406.47Benserazide
CAS :<p>Benserazide blocks dopa decarboxylase; paired with levodopa for Parkinson's to boost CNS dopamine levels and lower dosage.</p>Formule :C10H15N3O5Couleur et forme :SolidMasse moléculaire :257.24Batimastat sodium salt
CAS :Batimastat (BB-94) sodium salt is a broad-spectrum MMP inhibitor (IC50s: 3, 4, 4, 6, and 20 nM for MMP-1, MMP-2, MMP-9, MMP-7, and MMP-3).Formule :C23H31N3NaO4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :500.63NBI-42902
CAS :<p>NBI-42902 is a potent GnRH receptor antagonist (Ki=0.56 nm, Kd=0.19 nm), suppressing serum LH in macaques without causing histamine release.</p>Formule :C27H24F3N3O3Couleur et forme :SolidMasse moléculaire :495.49Chlophedianol Hydrochloride
CAS :<p>Chlophedianol hydrochloride: a cough suppressant for dry cough with antihistamine and local anesthetic traits; possibly anticholinergic at high doses.</p>Formule :C17H21Cl2NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :326.26Almokalant
CAS :<p>Almokalant: Class III antiarrhythmic, K+ channel blocker, inhibits Ikr current.</p>Formule :C18H28N2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :352.49Hemustine
CAS :<p>Hemustine is an inhibitor of human glutathione reductase and widely used as an anti-tumor agent.</p>Formule :C5H10ClN3O3Couleur et forme :SolidMasse moléculaire :195.6Evogliptin
CAS :<p>Evogliptin (DA-1229) is an oral DPP4 inhibitor effective in reducing blood sugar and liver inflammation.</p>Formule :C19H26F3N3O3Couleur et forme :SolidMasse moléculaire :401.42Evogliptin HCl
CAS :<p>Evogliptin (DA-1229), a DPP4 inhibitor, enhances insulin sensitivity and delays diabetes onset.</p>Formule :C19H27ClF3N3O3Couleur et forme :SolidMasse moléculaire :437.88Tropatepine
CAS :<p>Tropatepine: oral anticholinergic, treats extrapyramidal symptoms, anti-Parkinson's.</p>Formule :C22H23NSCouleur et forme :SolidMasse moléculaire :333.49Piribedil dihydrochloride
CAS :<p>dopamine agonist</p>Formule :C16H20Cl2N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :371.26(R)-ND-336
CAS :<p>(R)-ND-336: potent, selective MMP-9 inhibitor (K i = 19 nM); inhibits MMP-2 (127 nM), MMP-14 (119 nM); studied for diabetic foot ulcers.</p>Formule :C16H18ClNO3S2Couleur et forme :SolidMasse moléculaire :371.89Azatadine
CAS :<p>Azatadine is histamine and cholinergic inhibitor (IC50: 6.5 nM and 10 nM, respectively).</p>Formule :C20H22N2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :290.4Isopropamide
CAS :<p>Isopropamide (R5) is a long-acting anticholinergic for treating peptic ulcers and excessive gastric acid.</p>Formule :C23H33N2OCouleur et forme :SolidMasse moléculaire :353.52Deterenol Free Base
CAS :<p>Deterenol Free Base is a beta-adrenoceptor agonist.</p>Formule :C11H17NO2Couleur et forme :SolidMasse moléculaire :195.26Robenidine
CAS :<p>Robenidine, an anticoccidial guanidine, is used as an additive in rabbit fodder.</p>Formule :C15H13Cl2N5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :334.2Omeprazole Sodium
CAS :Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion.Formule :C17H18N3NaO3SDegré de pureté :99.84%Couleur et forme :Clear In WaterMasse moléculaire :367.4Ivaltinostat
CAS :<p>CG-200745 is a potent inhibitor of HDAC. CG200745 induces apoptosis and also inhibits the deacetylation of histone H3 and tubulin.</p>Formule :C24H33N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :427.54BR351
CAS :<p>BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).</p>Formule :C20H25FN2O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :424.49Thiochrome
CAS :<p>Thiochrome is a selective enhancer of M4 muscarinic receptor of acetylcholine (ACh) affinity.</p>Formule :C12H14N4OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :262.33Esreboxetine
CAS :<p>Esreboxetine( PNU-165442, (S,S) -reboxetine) is a selective inhibitor of norepinephrine reuptake.</p>Formule :C19H23NO3Couleur et forme :SolidMasse moléculaire :313.39Hexazinone
CAS :<p>Hexazinone: a triazine herbicide blocks photosynthesis by binding to D-1 protein in photosystem II.</p>Formule :C12H20N4O2Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :252.31Rufloxacin hydrochloride
CAS :<p>Rufloxacin HCl (MF-934 HCl): a fluoroquinolone that inhibits topoisomerase and B-cell differentiation.</p>Formule :C17H19ClFN3O3SDegré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :399.867TAK-875 Hemihydrate
CAS :TAK-875 Hemihydrate (Fasiglifam) is a selective GPR40 agonist with EC50 of 14 nM, 400-fold more potent than oleic acid.Formule :C29H32O7SH2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :533.631-Oxo mirtazapine
CAS :<p>1-Oxo mirtazapine is a metabolite of mirtazapine. It is a synthetic compound and is not found in nature. This product is a research and development impurity standard for the preparation of drug product, which has been synthesized to be highly pure. The material is used for drug development, including pharmacopoeia requirements for analytical studies and metabolism studies. 1-Oxo mirtazapine has been shown to have niche applications in pharmacopoeia and as an HPLC standard.</p>Formule :C17H17N3ODegré de pureté :Min. 95%Masse moléculaire :279.34 g/molPG-116800
CAS :<p>PG-116800 (PG-530742) is a matrix metalloproteinase (MMP) inhibitor. PG-116800 can be used in studies about the treatment of osteoarthritis.</p>Formule :C24H27N3O7SDegré de pureté :98.03% - 99.66%Couleur et forme :SolidMasse moléculaire :501.55Apixaban Impurity 6
CAS :<p>Please enquire for more information about Apixaban Impurity 6 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C26H26N4O5Degré de pureté :Min. 95%Masse moléculaire :474.51 g/molPramipexole EP Impurity C
CAS :<p>Pramipexole EP Impurity C is a synthetic impurity that is used as an impurity standard in the manufacture of Pramipexole EP. It is also used as a research and development tool for drug product, custom synthesis, CAS No. 1973461-14-1, and analytical studies. This compound has been shown to be a metabolite of Pramipexole EP and may have pharmacological properties. Pramipexole EP Impurity C has been found to inhibit the growth of certain bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA) isolates.</p>Formule :C20H32N6S2Degré de pureté :Min. 95%Vildagliptin carboxylic acid methyl ester
CAS :<p>Please enquire for more information about Vildagliptin carboxylic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C18H28N2O4Degré de pureté :Min. 95%Masse moléculaire :336.43 g/mol(S)-Rabeprazole sodium
CAS :<p>(S)-Rabeprazole sodium is an anticancer drug that acts as a kinase inhibitor. It is an analog of Rabeprazole and has been shown to inhibit the growth of cancer cells in vitro and in vivo. (S)-Rabeprazole sodium inhibits the activity of kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. (S)-Rabeprazole sodium has been tested against various types of cancer, including Chinese hamster ovary cells and tumor xenografts in mice. It has also been shown to inhibit elastin degradation, which is important for preventing metastasis of cancer cells. (S)-Rabeprazole sodium may be a promising candidate for the development of new anticancer drugs that target specific kinases and proteins involved in cancer cell growth and survival.</p>Formule :C18H21N3O3S•NaDegré de pureté :Min. 95%Masse moléculaire :382.43 g/molAmlodipine EP Impurity E maleate
CAS :<p>Amlodipine EP Impurity E maleate is a high purity and analytical grade chemical. It is a metabolite of Amlodipine, which is used in the treatment of hypertension. This chemical has been shown to be a natural product that is produced by the human body. It also has been shown to have pharmacological properties, such as anti-inflammatory and vasodilatory effects. The impurity standard for this compound is available from Sigma-Aldrich.br>br></p>Formule :C21H27ClN2O5•C4H4O4Degré de pureté :Min. 95%Masse moléculaire :538.98 g/molViloxazine
CAS :<p>Viloxazine (Viloxazin) (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and exhibits potent agonistic activity</p>Formule :C13H19NO3Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :237.29Gemigliptin
CAS :<p>Gemigliptin (LC15-0444) is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor(KD : 7.25 nM.)</p>Formule :C18H19F8N5O2Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :489.36Edoxaban
CAS :<p>Edoxaban: potent, selective FXa inhibitor; Ki 0.561 nM. Used as an oral anticoagulant for stroke prevention, also inhibits thrombin and FIXa.</p>Formule :C24H30ClN7O4SDegré de pureté :97.67% - 99.71%Couleur et forme :SolidMasse moléculaire :548.06Arimoclomol
CAS :<p>Arimoclomol (BRX-220 free base) is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (</p>Formule :C14H20ClN3O3Degré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :313.783-Trifluoroacetylamino linagliptin
CAS :<p>Please enquire for more information about 3-Trifluoroacetylamino linagliptin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C27H27F3N8O3Degré de pureté :Min. 95%Masse moléculaire :568.55 g/molPantoprazole sulphide
CAS :<p>Pantoprazole sulphide is a benzimidazole derivative that has been synthesized in an asymmetric synthesis. The purified compound was characterized by its nmr spectra, which showed the presence of the carboethoxy group and the chromatographic method. The compound belongs to a family of inhibitors known as benzimidazole derivatives and has shown inhibitory activity against a number of bacterial species including Staphylococcus aureus, Clostridium perfringens, and Mycobacterium tuberculosis. Pantoprazole sulphide has been used as an inhibitor to treat gastric acid pump disorders such as Zollinger-Ellison syndrome. It is also used for treating pathological conditions such as duodenal ulcers or gastroesophageal reflux disease.</p>Formule :C16H15F2N3O3SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :367.37 g/molCyamemazine
CAS :Cyamemazine is an antipsychotic compound with sedative and anxiolytic activity.Cyamemazine is a 5-HT3, 5-HT2A, and 5-HT2C receptor antagonist.Formule :C19H21N3SDegré de pureté :97.01%Couleur et forme :SolidMasse moléculaire :323.461-Fluoronaphthalene
CAS :<p>1-Fluoronaphthalene is a polyunsaturated compound that is used in analytical chemistry for the determination of test samples. It is an inhibitor of the enzyme IDO1, which plays an important role in the regulation of immune function, and has been shown to have anti-inflammatory properties. 1-Fluoronaphthalene can be synthesized by reacting n-dimethyl formamide with hydrogen fluoride and then adding a diazonium salt and hydrochloric acid. The UV absorption spectrum of 1-fluoronaphthalene displays a maximum at 248 nm. This compound binds to cation channels on cells, causing hyperpolarization.</p>Formule :C10H7FDegré de pureté :Min. 95%Masse moléculaire :146.16 g/molEltenac
CAS :<p>Eltenac, a cyclooxygenase (COX) inhibitor, is used potentially for the treatment of pain.</p>Formule :C12H9Cl2NO2SDegré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :302.18AGPS-IN-2i
CAS :AGPS-IN-2i inhibits alkylglycerol phosphate synthase, affecting ether lipid metabolism and reducing cancer cell migration and proliferation.Formule :C18H17F2N3O2Degré de pureté :98.92%Couleur et forme :SolidMasse moléculaire :345.34Givinostat hydrochloride
CAS :<p>Givinostat HCl (ITF2357 HCl) inhibits HDAC1/3 (IC50: 198/157 nM) with anti-inflammatory, anti-angiogenic, and antineoplastic properties.</p>Formule :C24H28ClN3O4Degré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :457.95
