Dérivés de Quinazoline et de Quinoléine
Les quinazolines et les quinoléines sont des composés hétérocycliques azotés à structure aromatique qui jouent un rôle clé dans la synthèse de médicaments à activité anticancéreuse, antimicrobienne et anti-inflammatoire. Leurs dérivés présentent des modifications structurelles qui optimisent leur biodisponibilité et leur sélectivité, permettant ainsi le développement de nouveaux principes actifs pour diverses applications thérapeutiques. Ces composés sont utilisés dans la fabrication d’API destinés au traitement du cancer, des infections, des maladies neurodégénératives et cardiovasculaires. De plus, les dérivés de quinazoline et de quinoléine sont essentiels dans la recherche d’inhibiteurs enzymatiques et dans la conception de molécules bioactives innovantes.
Chez CymitQuimica, nous proposons des dérivés de quinazoline et de quinoléine de haute pureté pour des applications en synthèse chimique, développement pharmaceutique et biotechnologie.
65630 produits trouvés pour "Dérivés de Quinazoline et de Quinoléine"
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N-[[(5S)-2-Oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-acetamide
CAS :Produit contrôlé<p>Applications N-[[(5S)-2-Oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-acetamide is an impurity of Rivaroxaban (R538000), which is a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.<br>References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),<br></p>Formule :C16H19N3O5Couleur et forme :NeatMasse moléculaire :333.34(±)-Albuterol-d3 (3-hydroxymethyl-d2; α-d1)
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications (±)-Albuterol-d3 (3-hydroxymethyl-d2; alpha-d1) (CAS# 1219798-60-3) is a useful isotopically labeled research compound.<br></p>Formule :C132H3H18NO3Couleur et forme :Off-WhiteMasse moléculaire :242.33Regorafenib
CAS :Produit contrôlé<p>Applications It inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent. Dual action VEGFR & Raf inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Leuner, C., et al.: Eur. J. Pharm. Biopharm., 50, 47 (2000),<br></p>Formule :C21H15ClF4N4O3Couleur et forme :Off White PowderMasse moléculaire :482.82Dehydro Aripiprazole
CAS :Produit contrôlé<p>Impurity Aripiprazole EP Impurity E; Aripiprazole USP Related Compound G<br>Applications Dehydro Aripiprazole (Aripiprazole EP Impurity E; Aripiprazole USP Related Compound G) is an impurity of Aripiprazole (A771000), a selective dopamine D2-receptor antagonist with dopamine autoreceptor agonist activity.<br>References Zeidan, T.A., et al.: Crystal. Growth. Design., 13, 2036 (2013); Nagasaka, Y., et al.: Biopharma. Drug. Dispo., 33, 304 (2012); Chen, X., et al.: J. Med. Chem., 55, 7141 (2012);<br></p>Formule :C23H25Cl2N3O2Couleur et forme :Off-WhiteMasse moléculaire :446.37Omeprazole sulfide N-Oxide
CAS :<p>Applications 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]thio]-1H-benzimidazole N-Oxide is a metabolite of Omeprazole (O635000), an proton inhibitor used as an antiulcerative agent.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983), Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984), Morii, M., et al.: J. Biol. chem., 268, 21553 (1993), Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Formule :C17H19N3O3SCouleur et forme :Off-WhiteMasse moléculaire :345.42Dehydro Amlodipine Oxalate
CAS :Produit contrôléFormule :C20H23ClN2O5·C2H2O4Couleur et forme :White To Off-WhiteMasse moléculaire :496.89(+/-)-4-Hydroxy Mephenytoin-d3
CAS :Produit contrôlé<p>Applications A deuterated CYP2C19 metabolite of Mephenytoin.<br>References Karlaganis, G., et al.: Drug Metab. Dispos., 8, 173 (1980)<br></p>Formule :C12H11D3N2O3Couleur et forme :White To Off-WhiteMasse moléculaire :237.274-(1-piperazinyl)quinazoline dihydrochloride dihydrate
Degré de pureté :95.0%Masse moléculaire :323.22000122070312,3:4,5-Bis-O-(1-methylethylidene)-β-D-fructopyranose 1-[[(diethylamino)carbonyl]sulfamate]
CAS :Produit contrôlé<p>Applications 2,3:4,5-Bis-O-(1-methylethylidene)-β-D-fructopyranose 1-[[(diethylamino)carbonyl]sulfamate] is an impurity of Topiramate (T540250), which is used as an anti-convulsant.<br>References Maryanoff, B.E., et al.: J. Med. Chem., 30, 880 (1987); Bialer, M.: Clin. Pharmacokinet., 24(6), 441-52 (1993)<br></p>Formule :C17H30N2O9SCouleur et forme :White To Off-WhiteMasse moléculaire :438.49rac FTY720 Phosphate
CAS :Produit contrôlé<p>Applications rac FTY720 is a sphingosine 1-phosphate receptor modular, ameliorates experimental autoimmune encephalomyelitis by inhibition of T cell infiltration.<br>References Igarashi, J., et al.: J. Biol. Chem., 275, 32363 (2000), Bandhuvula, P., et al.: J. Biol. Chem., 280, 33697 (2005),<br></p>Formule :C19H34NO5PCouleur et forme :NeatMasse moléculaire :387.45Thiophene
CAS :Produit contrôlé<p>Applications Thiophene is used as a building block of various organic molecules and pharmaceuticals providing functional properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Prasad, B. et al.: Chem. Comm., 48, 10434 (2012); Freitas, V. et al.: Struct. Chem., 24, 661 (2013);<br></p>Formule :C4H4SCouleur et forme :ColourlessMasse moléculaire :84.14FG 2216
CAS :Produit contrôlé<p>Applications FG 2216 is an erythropoietic agent which is orally active prolyl-hydroxylase inhibitor which increases erythropoietin production in end-stage kidney disease.<br>References Bernhardt, W., et al.: J. Am. Soc. Nephrol., 21, 2151 (2010)<br></p>Formule :C12H9ClN2O4Couleur et forme :WhiteMasse moléculaire :280.6645-Bromo-quinolin-8-ylamine hydrochloride
CAS :Formule :C9H8BrClN2Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :259.533-Hydroxy-5-methylisoxazole
CAS :Produit contrôléFormule :C4H5NO2Couleur et forme :White To OrangeMasse moléculaire :99.09N-(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)glycine
CAS :Produit contrôlé<p>Applications N-(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)glycine, is an impurity of Vildagliptin (V305000), a class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase.<br>References Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al.: Diabetes Care, 27, 2874 (2004), Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004),<br></p>Formule :C12H19NO3Couleur et forme :NeatMasse moléculaire :225.28Methyl 2-Iodobenzoate
CAS :Produit contrôlé<p>Stability Light Sensitive<br>Applications Methyl 2-Iodobenzoate is used as a reagent in the synthesis of Montelukast Sodium Salt (M568000); a selective leukotriene D4-receptor antagonist that is used as an antiasthmatic. Methyl 2-Iodobenzoate is also used as a reagent in the synthesis of isoquinolinone-based tricycles as polyribose polymerase-1 inhibitors.<br>References Bollikonda, S., et al.: J. Org. Chem., 80, 3891 (2015); Labelle, M., et al.: Bioorg. Med. Chem. Lett., 5, 283 (1995); Jones, T.R., et al.: Can. J. Physiol. Pharmacol., 73, 191 (1995); Markham, A. and Faulds, D.: Drugs, 56, 251 (1998); Chen, J., et al.: Bioorg. Med. Chem. Lett., 24, 2669 (2014)<br></p>Formule :C8H7IO2Couleur et forme :Colourless To Light YellowMasse moléculaire :262.0411-Morpholino-dibenzo[b,f][1,4]thiazepine
CAS :Produit contrôlé<p>Applications 11-Morpholino-dibenzo[b,f][1,4]thiazepine is part of a group of 11-(substituted-amino)dibenzo[b,f][1,4]thiazepine compounds that have analgesic and sedative properties.<br>References Schmutz, J. & Hunziker, F.: Patentschrift (Switz.), 7pp. (1969)<br></p>Formule :C17H16N2OSCouleur et forme :NeatMasse moléculaire :296.397-chloro-8-methyl-2-pyridin-4-ylquinoline-4-carboxylic acid
CAS :Degré de pureté :95.0%Masse moléculaire :298.7300109863281Flubendazole alcohol
CAS :Produit contrôlé<p>Applications Flubendazole alcohol is a metabolite of the anthelmintic Flubendazole (F418500).<br>References Meuldermans, W., et al.: Eur. J. Drug Metab. Pharmacokinet., 1, 35 (1976), Dusi, G., et al.: J. Pharmaceut. Biomed. Anal., 38, 375 (2005), Cvilink, V., et al.: Vet. Parasitol., 151, 242 (2008),<br></p>Formule :C16H14FN3O3Couleur et forme :White To Off-WhiteMasse moléculaire :315.301-(5-(BENZYLOXY)PYRIDIN-2-YL)CYCLOPROPANECARBOXYLIC ACID
Degré de pureté :95.0%Masse moléculaire :269.29998779296875N-Methyl β-Hydroxyl Phentermine
CAS :<p>Applications N-Methyl β-Hydroxyl Phentermine is derived from 2-Nitropropane (N519600), which is an oxidative stress-inducing agent and also a carcinogen. It is used in the induction of DNA polymerase β-dependent base excision repair in response to oxidative stress in the liver.<br>References Cabelof, D.C., et al.: Carcinogenesis,23, 1419 (2002); Kreis, P., et al.: Carcinogenesis, 21, 295 (2000)<br></p>Formule :C11H17NOCouleur et forme :Off-WhiteMasse moléculaire :179.26rac Penbutolol-d9
CAS :Produit contrôlé<p>Applications Labelled Penbutolol (P220500). A β-adrenoceptor antagonist. Antihypertensive.<br>References Armstrong, D., et al.: Anal. Chem., 66, 1473 (1994), Kato, M., et al.: J. Pharm. Biomed. Anal., 30, 1845 (2003),<br></p>Formule :C18H20D9NO2Couleur et forme :White To Off-WhiteMasse moléculaire :300.483-QUINOLINECARBOXYLIC ACID, 7-[(2-AMINOETHYL)AMINO]-1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-8-METHOXY-4-OXO-
CAS :Degré de pureté :97.0%Masse moléculaire :335.3349914550781Olaquindox
CAS :<p>Applications A growth stimulant.<br>References Barber, R.S., et al.: Anim. Feed Sci. Technol., 4, 117 (1979), Kwaga, J., et al.: Antimicrob. Agents Chemother., 34, 2423 (1990), Hugot, J., et al.: Lancet, 362, 2012 (2003),<br></p>Formule :C12H13N3O4Couleur et forme :NeatMasse moléculaire :263.25Desamino Imiquimod N-Oxide
CAS :Produit contrôlé<p>Impurity Imiquimod USP Related Compound B<br>Applications Desamino Imiquimod N-Oxide (Imiquimod USP Related Compound B) is a pharmacologically active compound related to Imiquimod (I475000), an immune response modifier. It stimulates the production of Interferon-a.<br>References Megyeri, K., et al.: Mol. Cell Biol., 15, 2207, (1995), Witt, P.L., et al.: Cancer Res., 53, 5176 (1993), Edwards, L., et al.: Arch. Dermatol., 134, 25 (1998); Gerster, J. et al.: J. Med. Chem., 48, 3481 (2005);<br></p>Formule :C14H15N3OCouleur et forme :NeatMasse moléculaire :241.29Etoricoxib N1’-Oxide
CAS :Produit contrôlé<p>Applications Etoricoxib N1’-Oxide is an impurity of Etoricoxib (E934100).<br>References Friesen, R., et al.: Bioorg. Med. Lett., 8, 2777 (1998), Botting, J., et al.: Drugs of Today, 35, 225 (19990, Talley, J., et al.: J. Med. Chem., 43, 775 (2000),<br></p>Formule :C18H15ClN2O3SCouleur et forme :NeatMasse moléculaire :374.84Sodium Azide
CAS :<p>Applications Sodium azide is commonly used as a preservative in aqueous laboratory reagents and biological samples. Sodium azide’s toxicity can be attributed to its role as a reversible inhibitor of mitochondrial respiration and insulin secretion in human pancreatic cells. Acts as a catalyst for: Oxidative decarboxylation & Michael addition reactions.Used as a reagent for synthesis of Blue fluorescent copolymers; Metal phosphonates & Arenes via aminations. Actively involved in regioselective synthesis of prianosin B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chang, S. & Lamm, S.: Int. J. Toxicol., 22, 175 (2003); Misler, S., et al.: Pflügers Archiv., 421, 289 (1992)<br></p>Formule :N3·NaCouleur et forme :White To Off-WhiteMasse moléculaire :65.01Nitrendipine Dipropyl Ester
CAS :<p>Applications Nitrendipine Dipropyl Ester is an analogue of the antihypertensive drug Nitrendipine (N490150). Also, Nitrendipine Dipropyl Ester is an impurity of antihypertensive Lercanidipine (L179000). Lercanidipine impurity B.<br>References Meyer, H., et al.: Arzneim.-Forsch., 31, 407 (1981),<br></p>Formule :C21H24N2O6Couleur et forme :NeatMasse moléculaire :400.421-(3-Chloropropyl)-1,3-dihydrobenzimidazol-2-one (>85%)
CAS :Produit contrôlé<p>Applications 1-(3-Chloropropyl)-1,3-dihydrobenzimidazol-2-one is a benzimidazole derivative used in the preparation of neuroleptic and antiallergic agents.<br>References Strupczewski, J. et al.: J. Med. Chem., 28, 761 (1985); Freter, K. et al.: Arzneim.-Forsch., 35, 272 (1985);<br></p>Formule :C10H11ClN2ODegré de pureté :~90%Couleur et forme :White To BeigeMasse moléculaire :210.663-Phenyl-5-vinyl-1,2,4-oxadiazole
CAS :<p>Stability Light Sensitive<br>Applications 3-Phenyl-5-vinyl-1,2,4-oxadiazole is a chemical reagent used in the synthesis of pharmaceutically active motifs.<br>References Burns, A. et al.: Org. Biomol. Chem., 8, 2777 (2010); Catanese, B. et al.: Exp. Mol. Path. Supp., 2, 28 (1963);<br></p>Formule :C10H8N2OCouleur et forme :NeatMasse moléculaire :172.183Methomyl
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Methomyl is a carbamate insecticide. Useful in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Armes, N., et al.: Bull. Entomol. Res., 86, 499 (1996); Shono, T., et al.: Pest. Biochem. Physiol., 75, 1 (2003)<br></p>Formule :C5H10N2O2SCouleur et forme :ColourlessMasse moléculaire :162.212-(3,4-Dichlorobenzoyl)-5-(1,3-dioxolan-2-yl)thiophene
CAS :Degré de pureté :97.0%Masse moléculaire :329.19000244140625Pyrrole-2-carboxaldehyde
CAS :Produit contrôléFormule :C5H5NOCouleur et forme :NeatMasse moléculaire :95.104-CHLORO-N-(PYRIDIN-2-YL)PYRIDIN-2-AMINE
CAS :Degré de pureté :90.0%Masse moléculaire :205.64999389648438Ref: 10-F531157
1gÀ demander2gÀ demander5gÀ demander10gÀ demander100mgÀ demander250mgÀ demander500mgÀ demander4-Diphenylmethoxypiperidine hydrochloride
CAS :<p>Stability Hygroscopic<br>Applications 4-Diphenylmethoxypiperidine, HCl<br></p>Formule :C18H21NO·ClHCouleur et forme :WhiteMasse moléculaire :303.83Rotigotine
CAS :<p>Rotigotine (1-Naphthalenol, 5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-) is an antiparkinson agent and dopamine receptor agonist.</p>Formule :C19H25NOSDegré de pureté :99.04% - 99.88%Couleur et forme :SolidMasse moléculaire :315.473-(1-Methanesulfonyl-3,5-dimethyl-1 H -pyrazol-4-yl)-propionic acid ethyl ester
CAS :Formule :C11H18N2O4SDegré de pureté :97%Couleur et forme :SolidMasse moléculaire :274.345-Naphthalen-1-yl-1H-pyrazole-3-carboxylic acid methyl ester
CAS :Degré de pureté :95.0%Masse moléculaire :252.27299499511724-Amino-1-ethylpyridin-2(1H)-one
CAS :Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :138.16999816894532-Pyridin-4-yl-2,3-dihydro-1H-quinazolin-4-one
CAS :Couleur et forme :SolidMasse moléculaire :225.251007080078123-Bromo-2-(chloromethyl)-6-fluoropyridine
CAS :Degré de pureté :95%Masse moléculaire :224.46000671386722-(2-Phenyl-2H-tetrazol-5-yl)pyridine
CAS :Degré de pureté :95.0%Masse moléculaire :223.23899841308594N-Nitroso Palbociclib 1
CAS :Produit contrôléFormule :C24H28N8O3Couleur et forme :NeatMasse moléculaire :476.542-(4-Bromonaphthalen-1-yl)-4,6-diphenyl-1,3,5-triazine
CAS :Degré de pureté :97%Masse moléculaire :438.32800292968754-[(quinolin-2-ylcarbonyl)amino]benzoic acid
CAS :Degré de pureté :95.0%Masse moléculaire :292.29400634765625seco-Ivabradine Amino Acid Sodium
CAS :Produit contrôléFormule :C27H37N2O6·NaCouleur et forme :NeatMasse moléculaire :486.60(5-amino-1-phenyl-1H-pyrazol-4-yl)(1H-indol-3-yl)methanone
CAS :Degré de pureté :95.0%Masse moléculaire :302.3370056152344
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