Dérivés de Quinazoline et de Quinoléine
Les quinazolines et les quinoléines sont des composés hétérocycliques azotés à structure aromatique qui jouent un rôle clé dans la synthèse de médicaments à activité anticancéreuse, antimicrobienne et anti-inflammatoire. Leurs dérivés présentent des modifications structurelles qui optimisent leur biodisponibilité et leur sélectivité, permettant ainsi le développement de nouveaux principes actifs pour diverses applications thérapeutiques. Ces composés sont utilisés dans la fabrication d’API destinés au traitement du cancer, des infections, des maladies neurodégénératives et cardiovasculaires. De plus, les dérivés de quinazoline et de quinoléine sont essentiels dans la recherche d’inhibiteurs enzymatiques et dans la conception de molécules bioactives innovantes.
Chez CymitQuimica, nous proposons des dérivés de quinazoline et de quinoléine de haute pureté pour des applications en synthèse chimique, développement pharmaceutique et biotechnologie.
65578 produits trouvés pour "Dérivés de Quinazoline et de Quinoléine"
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Desfluoro Ezetimibe
CAS :Produit contrôlé<p>Impurity Ezetimibe Desfluoroaniline Analog (USP)<br>Stability Hygroscopic<br>Applications An impurity of the cholesterol absorption inhibitor Ezetimibe (E975000). Ezetimibe Desfluoroaniline Analog (USP).<br>References Anon.: IP.com J., 7, 4 (2007);<br></p>Formule :C24H22FNO3Couleur et forme :White To Off-WhiteMasse moléculaire :391.437-Hydroxy-4-(3-pyridyl)coumarin
CAS :Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :239.22999572753906Dichlorodenafil
CAS :Produit contrôlé<p>Applications Dichlorodenafil is an unapproved Sildenafil (S435001) functions by inhibiting the phosphodiesterase type 5 enzyme (PDE-5).<br>References Kim, J.Y., et al.: Chem. Pharm. Bull., 61, 572 (2013)<br></p>Formule :C19H20Cl2N4O2Couleur et forme :SolidMasse moléculaire :407.29Methyl 2-Iodobenzoate
CAS :Produit contrôlé<p>Stability Light Sensitive<br>Applications Methyl 2-Iodobenzoate is used as a reagent in the synthesis of Montelukast Sodium Salt (M568000); a selective leukotriene D4-receptor antagonist that is used as an antiasthmatic. Methyl 2-Iodobenzoate is also used as a reagent in the synthesis of isoquinolinone-based tricycles as polyribose polymerase-1 inhibitors.<br>References Bollikonda, S., et al.: J. Org. Chem., 80, 3891 (2015); Labelle, M., et al.: Bioorg. Med. Chem. Lett., 5, 283 (1995); Jones, T.R., et al.: Can. J. Physiol. Pharmacol., 73, 191 (1995); Markham, A. and Faulds, D.: Drugs, 56, 251 (1998); Chen, J., et al.: Bioorg. Med. Chem. Lett., 24, 2669 (2014)<br></p>Formule :C8H7IO2Couleur et forme :Colourless To Light YellowMasse moléculaire :262.04N-(pyridin-2-ylmethyl)-1,3-benzothiazol-2-amine
CAS :Degré de pureté :95.0%Masse moléculaire :241.30999755859375N-cyclopropyl-2-(piperazin-1-yl)nicotinamide
CAS :Degré de pureté :97%Masse moléculaire :246.31399536132812Clofentezine
CAS :Produit contrôlé<p>Applications Clofentezine is a mite growth regular and an tetrazine based acaricide. Clofentezine is used in agriculture for the protection of ornamentals, food and non-food crops in the field.Used as a standard for Pesticide detection. Clofentezine is used in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bakirci, G.T., et al.; Food. Chem., 135, 1901 (2012); Ay, R., et al.: Insect. Sci., 18, 503 (2011);<br></p>Formule :C14H8Cl2N4Couleur et forme :NeatMasse moléculaire :303.15N-Formyl Lenalidomide
CAS :Produit contrôléFormule :C14H13N3O4Couleur et forme :NeatMasse moléculaire :287.274-[2-(2-methoxyethoxy)ethoxy]-6-(pyridin-2-yl)-2,2'-bipyridine
CAS :Degré de pureté :95.0%Masse moléculaire :351.406005859375Tert-Butyl 4-(quinazolin-4-ylamino)piperidine-1-carboxylate
CAS :Masse moléculaire :328.4159851074219Ethyl 2-cyclopropyl-4-(4-fluorophenyl)quinoline-3-carboxylate
CAS :Degré de pureté :95.0%Masse moléculaire :335.377990722656255-Chloro-N-cyclohexylpentanamide
CAS :<p>Stability Hygroscopic<br>Applications 5-Chloro-N-cyclohexylpentanamide (cas# 15865-18-6) is a compound useful in organic synthesis.<br></p>Formule :C11H20ClNOCouleur et forme :NeatMasse moléculaire :217.736Domperidone N-Oxide
CAS :Produit contrôlé<p>Impurity Domperidone EP Impurity C<br>Stability Hygroscopic<br>Applications Domperidone N-Oxide (Domperidone EP Impurity C) is an oxygenated metabolite of the gastrokinetic and antinauseant drug Domperidone (D531100).<br>References Van Vaeck, L. et al.: Biomed. Env. Mass Spec., 16, 121 (1988);<br></p>Formule :C22H24ClN5O3Couleur et forme :White To Off-WhiteMasse moléculaire :441.914-(4-ethoxyphenyl)-3-(pyridin-3-yl)-4,5-dihydro-1H-1,2,4-triazole-5-thione
CAS :Degré de pureté :97%Masse moléculaire :298.35998535156251,3-Adamantanediol
CAS :Produit contrôlé<p>Applications 1,3-Adamantanediol is used in the synthesis of novel dimethacrylate as possible dental monomers for dental resin mixtures.<br>References Wang, K. et al.: Mat. Sci. Eng. Mat. Biol. Appl., 32, 1141 (2012); Horino, Y. et al.: J. Mol. Catal. A. Chem.,<br></p>Formule :C10H16O2Couleur et forme :NeatMasse moléculaire :168.239,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-one (90%)
CAS :Produit contrôlé<p>Applications Intermediate in the preparation of Ketotifen.<br></p>Formule :C13H10OSDegré de pureté :90%Couleur et forme :NeatMasse moléculaire :214.28rac-Talinolol
CAS :Produit contrôlé<p>Applications Selective β1-adrenergic blocker structurally related to Practolol. Antihypertensive; antiarrhythmic.<br>References Assmann, I., et al.: Curr. Med. Res. Opin., 13, 325 (1995), Trausch, B., et al.: Biopharm. Drug Dispos., 16, 403 (1995),<br></p>Formule :C20H33N3O3Couleur et forme :White To Light PinkMasse moléculaire :363.492-(2-nitrophenyl)-1,4-dihydroquinazolin-4-one
CAS :Degré de pureté :95%Masse moléculaire :267.24398803710943-(4-methylphenyl)-1-phenyl-1H-pyrazole-4-carboxylic acid
CAS :Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :278.31100463867191,1'-Bis(4-formylphenyl)-[4,4'-bipyridine]-1,1'-diium
CAS :Degré de pureté :98%Masse moléculaire :366.41900634765625S-Amisulpride
CAS :Produit contrôlé<p>Applications S-Amisulpride is an isomer of the antipsychotic Amisulpride (A633250). S-Amisulpride has been shown to produce a maximal increase in prolactin level similar to that of the racemic form of Amisulpride.<br>References Protais, P., et al.: Neuropharmacol., 24, 861 (1985); Perrault, G., et al.: J. Pharmacol. Exp. Ther., 280, 73 (1997); Marchese, G., et. al.: Eur. J. Pharmacol., 448, 263 (2002)<br></p>Formule :C17H27N3O4SCouleur et forme :NeatMasse moléculaire :369.48Moclobemide
CAS :Produit contrôlé<p>Applications A reversible monoamine oxidase inhibitor.<br>References Wiesel, F.A., et al.: Eur. J. Clin. Pharmacol., 28, 89 (1985), Burkard, W.P., et al.: J. Pharmacol. Exp. Ther., 248, 391 (1989)<br></p>Formule :C13H17ClN2O2Couleur et forme :WhiteMasse moléculaire :268.74Levofloxacin Carboxylic Acid (Levofloxacin Difluoro Impurity)
CAS :Produit contrôlé<p>Impurity Levofloxacin USP Related Compound B<br>Applications Levofloxacin intermediate.<br>References Liu, Bo; Y., et al.: Bioorg. Med. Chem., 13, 2451 (2005), Lalitha D., et al.: J. Pharm. Biomed. Anal., 50, 710 (2009),<br></p>Formule :C13H9F2NO4Couleur et forme :NeatMasse moléculaire :281.21a-Desmethyl Anastrozole(>90%)
CAS :Produit contrôlé<p>Impurity Anastrozole EP Impurity A<br>Applications α-Desmethyl Anastrozole (Anastrozole EP Impurity A) is an impurity of Anastrozole (A637425) (impurity B).<br></p>Formule :C16H17N5Degré de pureté :>90%Couleur et forme :ColourlessMasse moléculaire :279.342-{[4-methyl-5-(thiophen-2-yl)-4h-1,2,4-triazol-3-yl]sulfanyl}acetic acid
CAS :Degré de pureté :95+%Masse moléculaire :255.30999764'-Methylbiphenyl-2-carbonitrile
CAS :Produit contrôlé<p>Applications 4'-Methylbiphenyl-2-carbonitrile is an intermediate in the synthesis of glycogen synthase kinase-3 inhibitors with a selective sting for glycogen synthase kinase 3α.<br>References Lo Monte, F., et al.: J. Med. Chem., 55, 4407 (2012); Schaarschmidt, D., et al.: ACS. Catalysis., 1, 411 (2011);<br></p>Formule :C14H11NCouleur et forme :NeatMasse moléculaire :193.24(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (2R)-Hydroxy(phenyl)ethanoate
CAS :<p>Applications (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine is an intermediate in the preparation of orally active reversible P2Y12 receptor antagonists such as Ticagrelor (T437700)for the prevention of thrombosis.<br>References Springthorpe, B. et al.: Bioorg. Med. Chem. Lett., 17, 6013 (2007);<br></p>Formule :C9H9F2N·C8H8O3Couleur et forme :NeatMasse moléculaire :321.32cis-ent-Tadalafil
CAS :Produit contrôlé<p>Impurity Tadalafil EP Impurity C<br>Applications The (6S)-cis-enantiomer of Tadalafil (T004500). Tadalafil Impurity (6S,12aR)<br>References Aldridge, J., et al.: Br. Med. J., 318, 669 (1999), Daugan, A., et al.: J. Med. Chem., 46, 4533 (2003), Vredenbregt, M., et al.: J. Pharm. Biomed. Anal., 40, 840 (2006),<br></p>Formule :C22H19N3O4Couleur et forme :White To Off-WhiteMasse moléculaire :389.40Saccharin N-(2-Acetic Acid Isopropyl Ester)(Piroxicam Impurity F)
CAS :Produit contrôlé<p>Impurity Piroxicam EP Impurity F<br>Applications Piroxicam impurity F.<br>References Lombardino, J., et al.: J. Med. Chem., 14, 1171 (1971), Turck, D., et al.: Clin. Drug Invest., 9, 270 (1995),<br></p>Formule :C12H13NO5SCouleur et forme :NeatMasse moléculaire :283.30[3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]methanol
CAS :Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :268.2909851074219(2-CHLOROPYRIDIN-4-YL)(1H-PYRROLO[3,2-C]PYRIDIN-3-YL)METHANONE
CAS :Degré de pureté :95.0%Masse moléculaire :257.679992675781254-{[(5Z)-3-[2-(3,4-dimethoxyphenyl)ethyl]-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}-2-methoxyphenyl thiophene-2-carboxylate
CAS :Masse moléculaire :541.6500244140625Hexametazidine
CAS :Produit contrôlé<p>Impurity Trimetazidine dihydrochloride EP impurity B<br>Applications Hexametazidine is an impurity of Trimetazidine (T795610). Trimetazidine impurity B. Hexametazidine can protect the myocardium from injury by ischemia and reperfusion.<br></p>Formule :C24H34N2O6Couleur et forme :NeatMasse moléculaire :446.541-(Pyrazin-2-yl)azetidin-3-amine dihydrochloride
CAS :Couleur et forme :Solid, Yellow solidMasse moléculaire :223.10000610351562Methyl 4-bromo-5-methyl-1H-pyrazole-3-carboxylate
CAS :Degré de pureté :95.0%Masse moléculaire :219.03799438476562Ref: 10-F214928
1gÀ demander2gÀ demander5gÀ demander10gÀ demander100mgÀ demander250mgÀ demander500mgÀ demander1-(1,3-Dimethyl-1H-pyrazol-4-yl)-4,4,4-trifluoro-butane-1,3-dione
CAS :Formule :C9H9F3N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :234.1784-Chloro-4'-fluorobutyrophenone
CAS :Produit contrôlé<p>Applications 4-Chloro-4'-fluorobutyrophenone (cas# 3874-54-2) is a compound useful in organic synthesis.<br></p>Formule :C10H10ClFOCouleur et forme :NeatMasse moléculaire :200.645,6-Dehydro-17a-Dutasteride
Produit contrôlé<p>Applications 5,6-Dehydro-17α-dutasteride is an epimer of 5,6-Dehydro-17β-dutasteride (D229560) an impurity in the synthesis of Dutasteride (D735000), a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.<br>References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995), Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999), Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005),<br></p>Formule :C27H28F6N2O2Couleur et forme :NeatMasse moléculaire :526.51N-(3-Morpholinopropyl) Gefitinib
CAS :Produit contrôlé<p>Applications N-(3-Morpholinopropyl) Gefitinib is a Gefitinib (G304000) impurity. It can also be synthesized from O-Desmorpholinopropyl Gefitinib (D296830).<br>References Anderson, N.G., et al.: Int. J. Cancer, 94, 774 (2001); Hirata, A., et al.: Cancer Res., 62, 2554 (2002); Kris, M.G., et al.: J. Am. Med. Assoc., 290, 2149 (2003); Tamura, K., et al.: Expert Opin. Pharmacother., 6, 985 (2005); Ranson, M., et al.: J. Clin. Oncology, 20, 2240 (2002); Mendelsohn, J., et al.: J. Clin. Oncology, 21, 2787 (2003); McKillop, D., et al.: Xenobiotica, 10, 917 (2004);<br></p>Formule :C29H37ClFN5O4Couleur et forme :NeatMasse moléculaire :574.087(R)-5-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole
CAS :Degré de pureté :95.0%Masse moléculaire :345.4200134277344N-Desmethyl Danofloxacin
CAS :<p>Applications A metabolite of Danofloxacin.<br>References Kiely, J.S., et al.: J. Med. Chem., 43, 656 (1991)<br></p>Formule :C18H18FN3O3Couleur et forme :NeatMasse moléculaire :343.353-methyl-1-(1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-1H-pyrazol-5-amine
CAS :Degré de pureté :95.0%Masse moléculaire :291.31799316406251-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
CAS :Produit contrôlé<p>Impurity Pethidine impurity B<br>Applications 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine is a dopaminergic neurotoxin that reportedly causes a severe and irreversible Parkinsonian condition in humans and monkeys.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Burns, R.S., et al.: Proc. Natl. Acad.Sci. USA, 80, 4546 (1983), Langston, J.W., et al.: Science, 219, 979 (1983), Mogi, M., et al.: Neurosci. Lett., 250, 25 (1998), Przedborski, S. and Jackson-Lewis, V., Mov. Disord., 13, 35 (1998),<br></p>Formule :C12H15NCouleur et forme :NeatMasse moléculaire :173.253-Phenyl-1-propanol
CAS :Produit contrôlé<p>Impurity Alverine EP Impurity B<br>Applications 3-Phenyl-1-propanol is used as a reagent in the synthesis of Dihydrocinnamyl Cilnidipine (D448605) and is a potent aroma biotransformation product.<br>References Bosse, A.K., et al.: Food Chem., 141, 2952 (2013)<br></p>Formule :C9H12OCouleur et forme :ColourlessMasse moléculaire :136.19N1,N3-Bis[2-(3,4-dimethoxyphenyl)ethyl]-N1,N3-dimethyl-1,3-propanediamine Dihydrochloride
CAS :Produit contrôlé<p>Impurity Verapamil EP Impurity A DIHCL<br>Stability Hygroscopic<br>Applications N1,N3-Bis[2-(3,4-dimethoxyphenyl)ethyl]-N1,N3-dimethyl-1,3-propanediamine Dihydrochloride (Verapamil EP Impurity A DIHCL) is an impurity of Verapamil (V125000), a calcium channel blocker. Antihypertensive; antianginal; antiarrhythmic (class IV).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Atlas, D, and Adler, M.: Proc. Natl. Acad. Sci. USA, 78, 1237 (1981), Janis, R., et al.: Adv. Drug. Res., 16, 309 (1987)<br></p>Formule :C25H38N2O4·2ClHCouleur et forme :NeatMasse moléculaire :503.51(R)-Tamsulosin-d4 Hydrochloride
CAS :Produit contrôlé<p>Applications (R)-Tamsulosin-d4 Hydrochloride is the labeled analogue of (R)-Tamsulosin Hydrochloride (T006350), a specific α1-adrenoceptor antagonist. It is used in the treatment of benign prostatic hypertrophy.<br>References Kawabe, K., et al.: J. Urol., 144, 908 (1990); Abrams, P., et al.: Br. J. Urol., 76, 325 (1995); Michel, M.C., Expert Opin. Pharmacother., 5, 151 (2004)<br></p>Formule :C20H25D4ClN2O5SCouleur et forme :NeatMasse moléculaire :449.04-Nitrophenethylamine Hydrochloride
CAS :Formule :C8H10N2O2·HClCouleur et forme :Light BeigeMasse moléculaire :166.18 + 36.46
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