Stéroïdes et Dérivés
Les stéroïdes sont des composés organiques possédant une structure de quatre cycles fusionnés, connue sous le nom de noyau stéroïdien. Ce noyau peut être associé à divers groupes fonctionnels modifiant leurs propriétés et leurs fonctions biologiques. Les stéroïdes jouent un rôle clé dans la régulation des processus métaboliques et hormonaux. Ils sont utilisés en médecine pour traiter les troubles inflammatoires, les maladies auto-immunes et les déséquilibres hormonaux. De plus, certains dérivés stéroïdiens possèdent de puissantes propriétés anti-inflammatoires, comme les corticostéroïdes. Dans certaines thérapies spécifiques, ils sont utilisés pour réduire l’inflammation et soulager la douleur dans diverses maladies.
Chez CymitQuimica, nous proposons une variété de stéroïdes et de leurs dérivés pour la recherche et le développement pharmaceutique.
4949 produits trouvés pour "Stéroïdes et Dérivés"
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Limaprost
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Limaprost is an analog of Prostaglandin E1 with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is used as an antianginal.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tsuboi, T., et al.: Arch. Int. Pharmacodyn., 247, 89 (1980), Adaikan, P.G., et al.: Prostaglandins Med., 6, 449 (1981), Kottegoda, S.R., et al.: Prostaglandins Leukotrienes Med., 8, 343 (1982), Ishizaki, T., et al.: Chest, 85, 382 (1984),<br></p>Formule :C22H36O5Couleur et forme :NeatMasse moléculaire :380.5217α-Dihydro Equilin
CAS :Produit contrôlé<p>Applications A metabolite of Equilin (E592800).<br>References Enmark, E., et al.: J. Clin. Endocrinol. Metab., 82, 4258 (1997), Wang, Z., et al.: J. Med. Chem., 43, 2419 (2000), Jiang, X., et al.: Steroids, 71, 334 (2006),<br></p>Formule :C18H22O2Couleur et forme :NeatMasse moléculaire :270.37Estrone-d2
CAS :Produit contrôlé<p>Applications Isotope labelled Estrone (E889050), which is a metabolite of 17β-Estradiol (E888000). During the metabolism, it is in rapid equilibrium with Estriol (E888960) and 17β-Estradiol (E888000) (1). Causes the feminization of male fish at human and animal waste sites (2).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Both, D. et al.: Anal. Prof. Drug Subst. 1983 12 pp135-1892. Goodman-Gruen, D. et al.: J. Clin. Endocrinol. Metab. 1996 Aug;81(8):2999-3003.<br></p>Formule :C182H2H20O2Couleur et forme :Off-WhiteMasse moléculaire :272.3817-epi-Ethynyl Estradiol
CAS :Produit contrôlé<p>Impurity Ethinylestradiol EP Impurity A<br>Applications 17-epi-Ethynyl Estradiol (Ethinylestradiol EP Impurity A) is the epimer derivative of Ethynyl Estradiol (E685100). An impurity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pomper, M., et al: J. Med. Chem., 33, 3143 (1990), Vulliet, E., et al.: Anal. Bioanal. Chem., 387, 2143 (2007), Muller, M., et al.: Environ. Toxicol. Chem., 27, 1649 (2008),<br></p>Formule :C20H24O2Couleur et forme :White To Off-WhiteMasse moléculaire :296.40Dexamethasone-biotin
CAS :Produit contrôlé<p>Applications Dexamethasone-biotin is biotin labelled Dexamethasone. Dexamethasone is a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase.<br>References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995), Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999), Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999)<br></p>Formule :C36H53FN4O6SCouleur et forme :NeatMasse moléculaire :688.895-β-Pregnane-3-α,20-α-diol
CAS :<p>Applications 5β-Pregnane-3α,20α-diol is a metabolite of Progesterone (P755900).<br>References Beall, et al.: Biochem. J., 31, 35 (1937), Okuda, A., et al.: J. Biol. Chem., 259, 7519 (1984), Russell, D., et al.: Biochemistry, 31, 4737 (1992), Kondo, K., et al.: Eur. J. Biochem., 219, 357 (1994), Westerbacka, J., et al.: J. Clin. Endocrinol. Metab., 88, 4924 (2003),<br></p>Formule :C21H36O2Couleur et forme :White To Off-WhiteMasse moléculaire :320.5122-Hydroxy Mifepristone
CAS :Produit contrôlé<p>Applications A metabolite of Mifepristone.<br>References Heikinheimo, O., et al.: J. Steroid Biochem., 26, 279 (1987), Brogden, R., et al.: Drugs, 45, 384 (1993), Shi, Y., et al.: Contraception, 48, 133 (1993), Jang, G., et al.: Biochem. Pharmacol., 52, 753 (1996), Gainer, E., et al.: Steroids, 68, 1005 (2003),<br></p>Formule :C29H35NO3Couleur et forme :NeatMasse moléculaire :445.59Triamcinolone Hexacetonide
CAS :Produit contrôlé<p>Applications Triamcinolone Hexacetonide is the Intra-articular glucocorticoid treatment for rheumatoid arthritis.<br>References Abd-El-Barr, M.M., et al.: J. Ocul. Pharmacol. Ther., 24, 197 (2007); Eberhard, B.A., et al.: J. Rheumatol., 31, 2507 (2004);<br></p>Formule :C30H41FO7Couleur et forme :WhiteMasse moléculaire :532.64Testosterone Enanthate-d3
CAS :Produit contrôlé<p>Applications Isotope labelled testosterone enanthate is a derivative of testosterone (T155000), the principal hormone of the testes, produced by the interstitial cells.<br>References Janjic, M.M., et al.: Reproduct. Toxicol., 34, 686 (2012); Lacreuse, A., et al.: Physiol. Behaviour., 106, 229 (2012);<br></p>Formule :C26H37D3O3Couleur et forme :Colourless To Off-WhiteMasse moléculaire :403.61Cholesterol 3-Acetate-d7
CAS :Produit contrôléFormule :C29H41D7O2Couleur et forme :NeatMasse moléculaire :435.736α-Hydroxy Progesterone (>80%)
CAS :Produit contrôléFormule :C21H30O3Degré de pureté :>80%Couleur et forme :NeatMasse moléculaire :330.46Estrone-d4
CAS :Produit contrôlé<p>Applications Isotope labelled Estrone (E889050), which is a metabolite of 17β-Estradiol (E888000). During the metabolism, it is in rapid equilibrium with Estriol (E888960) and 17β-Estradiol (E888000) (1). Causes the feminization of male fish at human and animal waste sites (2).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Both, D. et al.: Anal. Prof. Drug Subst. 1983 12 pp135-1892. Goodman-Gruen, D. et al.: J. Clin. Endocrinol. Metab. 1996 Aug;81(8):2999-3003.<br></p>Formule :C18D4H18O2Couleur et forme :White SolidMasse moléculaire :274.39Mifepristone-d3
CAS :Produit contrôlé<p>Applications A labelled progesterone receptor antagonist with partial agonist activity. Abortifacient.<br>References Healy, D.L., et al.: J. Clin. Endocrinol. Metab., 57, 863 (1983), Rauch, M., et al.: Eur. J. Biochem., 148, 213 (1985), Baulieu, E.E., et al.: Science, 245, 1351 (1989), Brogden, R.N., et al.: Drugs, 45, 384 (1993)<br></p>Formule :C29D3H32NO2Couleur et forme :Light Yellow SolidMasse moléculaire :432.61Triamcinolone Furetonide
CAS :Produit contrôléFormule :C33H35FO8Couleur et forme :NeatMasse moléculaire :578.62Flurandrenolone Acetate
CAS :<p>Impurity Fluocinolone Acetonide EP Impurity G<br>Applications Flurandrenolone Acetate, is the derivative of Flurandrenolide (F598650), which is a Glucocorticoid, used as an antipsoriatic.<br>References Pearlman, R., et al.: Int. J. Pharm., 18, 53 (1984), Neufeld, E., et al.: J. Chromatogr., 718, 273 (1998),<br></p>Formule :C26H35FO7Couleur et forme :NeatMasse moléculaire :478.55Dienogest-d8 (major)
CAS :Produit contrôlé<p>Applications Dienogest-d8 (major) is labelled derivative of 19-Nortestosterone. It is used in combination with estrogen as oral contraceptive.<br>References Hubner, M., et al.: Arzneim.-Forsch., 30, 401 (1980), Spona, J., et al.: Contraception, 56, 185 (1997), Foster, R.H., et al.: Drugs, 56, 825 (1998)<br></p>Formule :C20H17D8NO2Couleur et forme :Light YellowMasse moléculaire :319.47Paricalcitol
CAS :Produit contrôlé<p>Stability Light Sensitive, Temperature Sensitive<br>Applications Synthetic analog of vitamin D. Antihyperparathyroid.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sidek, H., et al.: Biochim. Biophys. Acta, 801, 26 (1984), Ciftci, M., et al.: J. Pharmacol., 54, 275 (2002),<br></p>Formule :C27H44O3Couleur et forme :NeatMasse moléculaire :416.64Testosterone Sulfate-d3 Triethylamine Salt
CAS :Produit contrôlé<p>Applications The labelled analogue of a metabolite of Testosterone (T155000). It is a urinary metabolite of Androstenedione (A637550) in patients with Addison's disease and also used as a marker in blood plasma for detection of prostate cancer.<br>References Lokhov, P.G. et al.: Metabolomics, 6, 156 (2010); Bonnaire, Y. et al.: J. Anal. Toxicol., 19, 175 (1995); Tamm, J. et al.: Steroids, 8, 659 (1966);<br></p>Formule :C25H40D3NO5SCouleur et forme :Off-WhiteMasse moléculaire :472.7Estradiol Enanthate
CAS :<p>Applications Estradiol Enanthate has been used as an injectable contraceptive.<br>References Coutinho, E.M., et. al.: Contraception, 73, 249 (2006)<br></p>Formule :C25H36O3Couleur et forme :BeigeMasse moléculaire :384.5511-Deoxy Prednisolone
CAS :Produit contrôlé<p>Impurity Prednisolone EP Impurity J<br>Applications 11-Deoxy Prednisolone (Prednisolone EP Impurity J) is a Prednisolone (P703740) derivative as a corticosteroid.<br>References Kobayashi, Y., et al.: Biol. Pharm. Bull., 16, 1175 (1993), Ogata, M., et al.: J. Pharm. Sci., 87, 91 (1998), Hou, S., et al.: J. Pharm. Biomed. Anal., 24, 371 (2001),<br></p>Formule :C21H28O4Couleur et forme :Light BrownMasse moléculaire :344.445β-Dihydrocortisol-d6
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications 5β-Dihydrocortisol-d6 is an isotope labelled analog of 5β-Dihydrocortisol (D448595). 5β-Dihydrocortisol, is a derivative of Cortisol (H714615), which is a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland.<br>References Vigore, L., et al.: Cancer Ther., 6, 699 (2008), Puurunen, J., et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009), Lemos, D., et al.: J. Endocrinol., 201, 275 (2009), Chen, S., et al.: Am. J. Physiol., 296 (2009),<br></p>Formule :C21H26D6O5Couleur et forme :NeatMasse moléculaire :370.51Betamethasone 17-Valerate
CAS :Produit contrôlé<p>Applications Betamethasone 17-Valerate is a corticosteroid with anti-inflammatory properties. Topical application of Betamethasone 17-Valerate has been shown to inhibit heat-induced vasodilatation in man.<br>References Banfi, S. et al.: Curr. Ther. Res., 19, 126 (1976); Ahluwalia, A. et al.: Br. J. Dermatol., 128, 45 (1993);<br></p>Formule :C27H37FO6Couleur et forme :WhiteMasse moléculaire :476.5817β-Estradiol-d3 17-Acetate
CAS :Produit contrôlé<p>Applications Protected Estradiol.<br>References Miilunpohja, M., et al.: J. Steroid Biochem. Mol. Biol., 100, 59 (2006), Ikonomou, M., et al.: Environ. Toxicol. Chem., 27, 243 (2008),<br></p>Formule :C20H23D3O3Couleur et forme :NeatMasse moléculaire :317.44Testosterone 17-O-Acetate
CAS :Produit contrôlé<p>Applications An Androgen.Controlled substance.<br>References Alikhan, A., et al.: J. App. Toxicol., 29, 590 (2009), Christy H., et al.: J. Steroid Biochem. Mol. Biol., 116, 171 (2009), Li, C., et al.: Steroids, 75, 859 (2010),<br></p>Formule :C21H30O3Couleur et forme :NeatMasse moléculaire :330.4617α-Hydroxy Progesterone-d8
CAS :Produit contrôlé<p>Applications Labelled 17α-Hydroxyprogesterone (H952330). 17α-Hydroxy Progesterone is a metabolite of Progesterone. It was isolated from adrenal glands.<br>References Pfiffner, N., et al.: J. Biol. Chem., 132, 459 (1940), Florey, K., et al.: Anal. Profiles Drug Subs.,4, 209 (1975),<br></p>Formule :C212H8H22O3Couleur et forme :Off-WhiteMasse moléculaire :338.5117β-Estradiol-16,16,17-d3 3-Benzoate
CAS :Produit contrôlé<p>Applications 17beta-Estradiol-16,16,17-d3 3-Benzoate (CAS# 1192354-74-7) is a useful isotopically labeled research compound.<br></p>Formule :C25H25D3O3Couleur et forme :NeatMasse moléculaire :379.514-Hydroxy Estrone
CAS :Produit contrôléFormule :C18H22O3Couleur et forme :Light Brown SolidMasse moléculaire :286.37Estradiol-13C2 17-Benzoate
CAS :<p>Applications Estradiol-13C2 17-Benzoate is an intermediate in the synthesis of 17β-Estradiol-13C2 (E888003). Isotope labelled 17β-Estradiol (E888000) is the major estrogen (1) secreted by the premenopausal ovary (2).<br></p>Formule :C2313C2H28O3Degré de pureté :>90%Couleur et forme :NeatMasse moléculaire :378.47Fluocinolone Acetonide-21-aldehyde
CAS :<p>Impurity Fluocinolone Acetonide EP Impurity D<br>Stability Hygroscopic<br>Applications Fluocinolone acetonide-21-aldehyde, is a derivative of Fluocinolone Acetonide (F455800), which is a Corticosteroid, used in dermatology to reduce skin inflammation and relieve itching.<br>References Sammul, et al.: J. Assoc. Off. Agric. Chem., 47, 952 (1964), Emerson, M.V., et al.: BioDrugs, 21, 245 (2007),<br></p>Formule :C24H28F2O6Couleur et forme :White To Light YellowMasse moléculaire :450.47Aldosterone-d7 (Major)
CAS :Produit contrôléFormule :C21H21D7O5Couleur et forme :NeatMasse moléculaire :367.49Clobetasone 17-Propionate
CAS :Produit contrôlé<p>Impurity Clobetasone Butyrate EP Impurity H<br>Applications Clobetasone-17-propionate is derived from Clobetasol (Clobetasol Propionate EP Impurity G) (C583490), which is a topical corticosteroid. Glucocorticoid; anti-inflammatory.<br>References Olsen, E.A., et al.: J. Am. Acad. Dermatol., 15, 246 (1986)<br></p>Formule :C25H30ClFO5Couleur et forme :NeatMasse moléculaire :464.95Oxandrolone
CAS :Produit contrôlé<p>Applications A synthetic, anabolic steroid. Used to promote muscle growth and combat involuntary weight loss. It has also been used to treat cases of osteoporosis.<br>References Cadwallader, A., et al.: Mol. Pharm., 7, 689 (2010), Amundson, E., et al.: J. Clin. Endocrinol. Metabol., 95, 1355 (2010), Bovee, T., et al.: J. Steroid Biochem. Mol. Biol., 118, 85 (2010), Fourches, D., et al.: Chem. Res. Toxicol., 23, 171 (2010),<br></p>Formule :C19H30O3Couleur et forme :White To Off-WhiteMasse moléculaire :306.44Testosterone Enanthate
CAS :Produit contrôlé<p>Applications Testosterone Enanthate is a derivative of testosterone (T155000), the principal hormone of the testes, produced by the interstitial cells.<br>References Janjic, M.M., et al.: Reproduct. Toxicol., 34, 686 (2012); Lacreuse, A., et al.: Physiol. Behaviour., 106, 229 (2012);<br></p>Formule :C26H40O3Couleur et forme :Colourless To Off-WhiteMasse moléculaire :400.594’-Hydroxy Dutasteride
Produit contrôlé<p>Applications 4’-Hydroxy Dutasteride is an impurity of Dutasteride (D735000), a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.<br>References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995), Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999), Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005)<br></p>Formule :C27H30F6N2O3Couleur et forme :NeatMasse moléculaire :544.53(7α,11α,12α,17α)-11,12-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Lactone, Methyl Ester
CAS :<p>Applications (7α,11α,12α,17α)-11,12-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Lactone, Methyl Ester is an impurity of eplerenone (E588775). Eplerenone is a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.<br>References de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (2001), Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (2004), Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (2005),<br></p>Formule :C24H30O6Couleur et forme :NeatMasse moléculaire :414.491Travoprost
CAS :<p>Stability Light Sensitive<br>Applications Travoprost is a selective FP prostaglandin receptor agonist used to treat glaucoma (1,2).<br>References (1) Hellberg, M.R., et al.: J. Ocul. Pharmacol. Ther., 17, 421 (2001) (2) Schuman, J.S., et al.: Am. J. Ophthalmol., 140, 242 (2005)<br></p>Formule :C26H35F3O6Couleur et forme :Colourless To BeigeMasse moléculaire :500.556-Defluoro-6-oxo-fluticasone Propionate
<p>Stability Temperature Sensitive<br>Applications 6-Defluro-6-oxo-fluticasone Propionate is a derivative of Flumethasone (F455000), a glucocorticoid, anti-inflammatory.<br>References Matuszewski, B, et al.: Anal. Chem., 75, 3019 (2003), Fekete, S., et al.: J. Pharm. Biomed. Anal., 49, 64 (2009),<br></p>Formule :C25H30F2O6SCouleur et forme :Off-WhiteMasse moléculaire :496.566-Keto Ethynyl Estradiol
CAS :Produit contrôlé<p>Impurity Ethinylestradiol EP Impurity G<br>Applications An oxidative tranformation product of Norethindrone Acetate (N675990) and Ethynyl Estradiol (E685100).<br>References Ekhato, I.V. et al.: Steroids, 67, 165 (2002); Lane. P.A. et al.: J. Pharmac. Sci., 76, 44 (1987);<br></p>Formule :C20H22O3Couleur et forme :Light Yellow To Light BrownMasse moléculaire :310.3925-Hydroxy Vitamin D3 3-Sulfate Sodium Salt (90%)
CAS :Produit contrôlé<p>Stability Light Sensitive, Temperature Sensitive<br>Applications 25-Hydroxyvitamin D3 3-Sulfate is a metabolite of 24,25-Dihydroxyvitamin D3 and 25-Hydroxyvitamin D3 (C125700).<br>References Higashi, T. et al.: Steroids, 65, 281 (2000); Higashi, T. et al.: Ann. Clin. Biochem., 36, 43 (1999);<br></p>Formule :C27H43NaO5SDegré de pureté :90%Couleur et forme :NeatMasse moléculaire :502.68Testosterone-2,2,4,6,6-d5 (1 mg/ml in Acetonitrile)
CAS :Produit contrôléFormule :C192H5H23O2Couleur et forme :ColourlessMasse moléculaire :293.46Triamcinolone
CAS :Formule :C21H27FO6Couleur et forme :White To Light YellowMasse moléculaire :394.43(-)-Estra-4,9-diene-3,17-dione
CAS :Produit contrôlé<p>Applications A potential metabolite of STS 557 (Dienogest)(D441870). A steroid with antiglucocorticoid activity.<br>References Kloosterboer, H., et al.: J. Steroid Biochem., 31, 567 (1988),<br></p>Formule :C18H22O2Couleur et forme :NeatMasse moléculaire :270.375β-Dihydro Progesterone-d8
CAS :Produit contrôlé<p>Applications 5β-Dihydro Progesterone-d8 is labelled which is labelled 5β-Dihydro Progesterone (D449280), a metabolite of the neuroactive steroid Progesterone (PROG) (P755900).<br>References Wiebe, J., et al.: Cancer Res., 60, 936 (2000), Lacasa, D., et al.: J. Biol. Chem., 276, 11512 (2001), Johansson, I., et al.: Brain Res., 934, 125 (2002), Leonhardt, S., et al.: Steroids, 68, 761 (2003),<br></p>Formule :C21H24D8O2Couleur et forme :NeatMasse moléculaire :324.53Dexamethasone 21-Mesylate
CAS :Produit contrôlé<p>Stability Moisture Sensitive<br>Applications Dexamethasone 21-Mesylate is a derivative of Dexamethasone (D298800), a glucocorticoid used as an anti-inflammatory agent.<br>References Kim, T.H., et al.: J. Nanosci. Nanotech., 13, 7325 (2013); Joshi, T., et al.: Brit. J. Pharmacol., 172, 1360 (2015);<br></p>Formule :C23H31FO7SCouleur et forme :NeatMasse moléculaire :470.55Mifepristone
CAS :Produit contrôlé<p>Applications Mifepristone is a progesterone receptor antagonist with partial agonist activity. Abortifacient.<br>References Healy, D.L., et al.: J. Clin. Endocrinol. Metab., 57, 863 (1983), Rauch, M., et al.: Eur. J. Biochem., 148, 213 (1985), Baulieu, E.E., et al.: Science, 245, 1351 (1989), Brogden, R.N., et al.: Drugs, 45, 384 (1993)<br></p>Formule :C29H35NO2Couleur et forme :White To Light YellowMasse moléculaire :429.594-Hydroxy Ospemifene (Ospemifene Impurity)
CAS :<p>Applications 4-Hydroxy Ospemifene is an Ospemifene (O703000) impurity, used to treat dyspareunia. It is a selective estrogen receptor modulator (SERM) acting similarly to an estrogen.<br>References Rutanen, E., et al.: Menopause, 10, 433 (2003);<br></p>Formule :C24H23ClO3Couleur et forme :NeatMasse moléculaire :394.89Digitoxin-21,23,23-d3
CAS :Produit contrôlé<p>Applications Isotope labelled Digitoxin (D445950), is used as a cardiotonic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Foerster, et al.: Arch. Int. Pharmacodyn. Ther., 159, 1 (1966), Jakovljevic, I.M., Anal. Profiles Drug Subs., 3, 149 (1974)<br></p>Formule :C41H61D3O13Degré de pureté :90%Couleur et forme :NeatMasse moléculaire :767.96Desmosterol-d6
CAS :Produit contrôlé<p>Applications A labelled metabolite of Cholesterol (C432501).<br>References Marx, J., et al.: Science, 294, 508 (2001), Plosch, T., et al.: J. Biol. Chem., 277, 33870 (2002), Lund, E., et al.: J .Biol. Chem., 278, 22980 (2003),<br></p>Formule :C272H6H38OCouleur et forme :NeatMasse moléculaire :390.67Testosterone Undecanoate-d3
CAS :Produit contrôlé<p>Applications A Labelled metabolite of Testosterone (T155000). It is a promising androgen for male hormonal contraception.CONTROLLED SUBSTANCE<br>References Glass, A., et al.: J. Clin. Endocrinol. Metab., 45, 1211 (1977), Behre, H., et al.: Eur. J. Endocrinol., 140, 414 (1999), Nieschlag, E., et al.: Steroids, 68, 965 (2003), Wang, C., et al.: J. Clin. Endocrinol. Metab., 91, 460 (2006),<br></p>Formule :C30H45D3O3Couleur et forme :NeatMasse moléculaire :459.729,11-Didehydrooestriol
CAS :Produit contrôlé<p>Impurity Estriol EP Impurity A<br>Stability Hygroscopic<br>Applications 9,11-Didehydrooestriol (Estriol EP Impurity A) is an impurity of Estriol (E888960), a metabolite of Estradiol (E888000). An estrogenic metabolite considerably less potent than the hormone Estradiol (E888000).<br>References Marrian, et al.: Biochem. J., 23,1090 (1929), Huffman, et al.: J. Biol. Chem., 169, 167 (1947),<br></p>Formule :C18H22O3Couleur et forme :Off-WhiteMasse moléculaire :286.3719-Hydroxy Cholesterol
CAS :<p>Applications A metabolite of Cholesterol. Cholesterol oxidation product having cytotoxicity effects.<br>References Higley, N., et al.: Food Chem. Toxicol., 22, 983 (1984), Emanuel, H., et al.: J. Food Sci., 56, 843 (1991), Kilsdonk, E., et al.: J. Lipid Res., 36, 505 (1995), Cantwell, H., et al.: Cell Biol. Toxicol., 14, 401 (1998),<br></p>Formule :C27H46O2Couleur et forme :NeatMasse moléculaire :402.65(Z)-Guggulsterone
CAS :Produit contrôlé<p>Applications (Z)-Guggulsterone acts as an α-glucosidase inhibitor also known as a hypolipidemic agent.<br>References Yang, D. et al.: J. Lipid Res., 53, 529 (2012); El-Mekkawy, S. et al.: Nat. Prod. Res., 27, 146 (2013);<br></p>Formule :C21H28O2Couleur et forme :NeatMasse moléculaire :312.45(16β)-17,21-Dihydroxy-16β-methyl-pregna-1,4,9(11)-triene-3,20-dione
CAS :Produit contrôlé<p>Impurity Betamethasone EP Impurity C<br>Applications (16β)-17,21-Dihydroxy-16β-methyl-pregna-1,4,9(11)-triene-3,20-dione (Betamethasone EP Impurity C) is used in biological studies to perform preclinical characterization of VBP15, a novel anti-inflammatory delta 9,11 steroid. This compound is also used in analytical studies to determine the stability from reversed-phase high performance liquid chromatography (RP-HPLC) to separate low levels of dexamethasone and other related compounds from betametasone, which is an active pharmaceutical ingredient.<br>References Reeves, E.K.M., et al.: Bioorg., Med. Chem., 21, 2241 (2013), Xiong, Y., et al.: J. Pharm. Biomed. Anal., 49, 646 (2009)<br></p>Formule :C22H28O4Couleur et forme :NeatMasse moléculaire :356.46Testosterone Undecylenate
CAS :Produit contrôlé<p>Applications Testosterone Undecylenate is an ester metabolite of Testosterone (T155000), which is the main hormone of the testes, produced by the interstitial cells. It is a major circulating androgen; converted by 5α-reductase in androgen-dependent target tissues to 5α-dehydrotestosterone that is required for normal male sexual differentiation. Also converted by aromatization to Estradiol.<br>References McFarland, K., et al.: Science, 245, 494 (1989); Heckert, L., et al.: Mol. Endocrinol., 12, 1499 (1998); Themmen, A., et al.: Endocr. Rev. 21, 551 (2000); Kumar, R., et al.: Biol. Reprod., 65, 710 (2001);<br></p>Formule :C30H46O3Couleur et forme :NeatMasse moléculaire :454.684Digitoxin
CAS :<p>Stability Hygroscopic<br>Applications Cardiotonic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Foerster, et al.: Arch. Int. Pharmacodyn. Ther., 159, 1 (1966), Jakovljevic, I.M., Anal. Profiles Drug Subs., 3, 149 (1974)<br></p>Formule :C41H64O13Couleur et forme :White To Off-WhiteMasse moléculaire :764.9420(α)-Dihydro Pregnenolone
CAS :<p>Applications 20α-Dihydro Pregnenolone is a metabolite of Pregnenolone (P712200).<br>References Purdy, R., et al.: J. Med. Chem., 33, 1572 (1990), Bixo, M., et al.: Brain Res., 764, 173 (1997), Huang, X., et al.: J. Biol. Chem., 275, 29452 (2000),<br></p>Formule :C21H34O2Couleur et forme :NeatMasse moléculaire :318.49Testosterone 17-Isobutyrate
CAS :Produit contrôlé<p>Applications Testosterone ester.<br>References Zarzycki, P., et al.: Anal. Bioanal. Chem., 391, 2219 (2008), Talarovicova, A., et al.: Hormon. Behav., 55, 235 (2009),<br></p>Formule :C23H34O3Couleur et forme :Off-WhiteMasse moléculaire :358.51Flurandrenolide
CAS :Produit contrôlé<p>Applications Glucocorticoid; antipsoriatic.<br>References Pearlman, R., et al.: Int. J. Pharm., 18, 53 (1984), Neufeld, E., et al.: J. Chromatogr., 718, 273 (1998),<br></p>Formule :C24H33FO6Couleur et forme :NeatMasse moléculaire :436.51Finasteride Carboxylic Acid Methyl Ester
CAS :Produit contrôlé<p>Applications Finasteride Carboxylic Acid Methyl Ester is an metabolite of Finasteride (F342000), an inhibitor of 5α-reductase, the enzyme which converts testosterone to the more potent androgen, 5α-dihydrotestosterone.<br>References Koronkowski, M.J., et al.: Pharmacotherapy, 13, 309 (1993), Tenover, J.L., et al.: Clin. Ther., 19, 243 (1997), McConnell, J.D., et al.: N. Engl. J. Med., 338, 557 (1998),<br></p>Formule :C24H36N2O4Couleur et forme :NeatMasse moléculaire :416.554Dexamethasone Acid Ethyl Ester
CAS :<p>Applications Dexamethasone Acid Ethyl Ester is a derivative of Dexamethasone (D298800), a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase.<br>References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995), Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999), Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999)<br></p>Formule :C23H31FO5Couleur et forme :Off-WhiteMasse moléculaire :406.49BGP 15
CAS :Produit contrôlé<p>Applications BGP 15 is a calcipotriene-based vitamin D3 analog that inhibits poly(ADP-ribose) polymerasesis (PARP), a class of enzymes that regulate DNA repair and apoptosis (1). BGP 15 is also a cardioprotective agent (2). Also, BPG 15 improves mitochondrial function, protects neurons from dying in vitro and in vivo, and promotes cardiac innervation in vivo.<br>References (1) Berkovich, L., et al.: Anticancer Drugs. 21, 609 (2010) (2) Szabados, E., et al. Biochem Pharmacol. 59, 937 (2000)<br></p>Formule :C14H22N4O2·2HClCouleur et forme :NeatMasse moléculaire :351.272-Hydroxy-17β-estradiol
CAS :<p>Applications A metabolite of Estradiol.<br>References Bucala, R., et al.: J. Clin. Endocrinol. Metab., 60, 841 (1985), Telang, N., et al.: Anticancer Res., et al.: 11, 1021 (1991), Seeger, H., et al.: Med. Sci. Res., 26, 481 (1998), Bolton, J., et al.: Chem. Res. Toxicol., 13, 135 (2000),<br></p>Formule :C18H24O3Couleur et forme :Light Yellow To Dark YellowMasse moléculaire :288.38Prednisolone Tebutate
CAS :Produit contrôlé<p>Applications Prednisolone Tebutate is an anaesthetic corticosteroid.<br>References Lewis, A. et al.: Agents and Actions, 10, 258 (1980); Myers, S. et al.: Arthris. Rheum., 28, 1275 (1985);<br></p>Formule :C27H38O6Couleur et forme :NeatMasse moléculaire :458.595,24-Stigmastadienol
CAS :Produit contrôléFormule :C29H48OCouleur et forme :NeatMasse moléculaire :412.691Diethylstilbestrol Dipropionate
CAS :<p>Applications Diethylstilbestrol dipropionate<br></p>Formule :C24H28O4Couleur et forme :White To Off-WhiteMasse moléculaire :380.48Oleandrin
CAS :<p>Applications Cardiotonic; diuretic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sreenivasan, Y., et al.: Biochem. Pharmacol., 66, 2223 (2003), Ni, D., et al.: J. Exp. Ther. Oncol., 2, 278 (2002), Langford, S.D., Toxicology, 109,1 (1996),<br></p>Formule :C32H48O9Couleur et forme :White To Off-WhiteMasse moléculaire :576.7217-Iodo-androsta-5,16-diene-3β-ol
CAS :Produit contrôlé<p>Impurity Abiraterone Impurity 5<br>Applications 17-Iodo-androsta-5,16-diene-3β-ol is an analog of Abiraterone (A108490) and is used as a reagent in the synthesis of C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens which exhibit antitumor activity. Abiraterone Impurity 5<br>References Handratta, V.D., et al.: J. Med. Chem., 48, 2972 (2005)<br></p>Formule :C19H27IOCouleur et forme :White To Off-WhiteMasse moléculaire :398.32Cyproterone-d4
CAS :Produit contrôlé<p>Applications Labelled Cyproterone (C989090). An antiandrogen, suppresses Testosterone and its metabolites. Derivatives of Cyproterone are administered to patients suffering from hypersexuality and to help facilitate the sexual transformation of male-to-female transsexuals.<br>References Gracia, T., et al.: Toxicol. App. Pharmacol., 225, 142 (2007), Ahlin, G., et al.: J. Med. Chem., 51, 5932 (2008), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Bovee, T., et al.: J. Steroid Biochem. Mol. Biol., 118, 85 (2010),<br></p>Formule :C22H23D4ClO3Couleur et forme :NeatMasse moléculaire :378.9316α-Homo 2-(Hydroxymethyl)betamethasone
CAS :Produit contrôléFormule :C22H29FO5Couleur et forme :NeatMasse moléculaire :392.461Progesterone 3-(O-carboxymethyl)oxime
CAS :Produit contrôlé<p>Applications Progesterone 3-(O-carboxymethyl)oxime is used in microtitre plate enzyme immunoassays (EIAs) for progesterone.<br></p>Formule :C23H33NO4Couleur et forme :NeatMasse moléculaire :387.512Fluvastatin
CAS :<p>Fluvastatin (XU-62320) is an HMG-CoA reductase inhibitor used to lower plasma cholesterol levels and prevent cardiovascular disease.</p>Formule :C24H26FNO4Degré de pureté :98.94%Couleur et forme :SolidMasse moléculaire :411.47Palovarotene
CAS :Produit contrôlé<p>Applications Palovarotene, is a highly selective retinoic acid receptor gamma (RAR-γ) agonist that is under investigation as a potential treatment for emphysema.<br>References Hind, M., et al.: Curr. Opinion Invest. Drugs, 10(11), 1243 (2009); Stolk, J., et al.: Therap. advances Respi. dise., 4, 319 (2010);<br></p>Formule :C27H30N2O2Couleur et forme :NeatMasse moléculaire :414.54Testosterone Laurate
CAS :Produit contrôléFormule :C31H50O3Couleur et forme :White To Off-WhiteMasse moléculaire :470.73δ1-Adrenosterone
CAS :Produit contrôlé<p>Applications Δ1-Adrenosterone is a derivative of Adrenosterone (A305600), and is suspected to have some inhibitory effects on estrogen biosynthesis in human placental microsomes. Δ1-Adrenosterone also has potential androgenic anabolic and antiuterotropic activity.<br>References Lodge, B., et al.: Can. J. Pharm. Sci., 10, 107 (1975); Lodge, B., et al.: Can. J. Pharm. Sci., 11, 95 (1976); Schwarzel, W., et al.: Endocrinology, 92, 866 (1973)<br></p>Formule :C19H22O3Couleur et forme :NeatMasse moléculaire :298.386α-Methyl-9α-fluoro-11β,17α-dihydroxyprogesterone
CAS :Produit contrôlé<p>Applications 6α-Methyl-9α-fluoro-11β,17α-dihydroxyprogesterone is an impurity of Fluorometholone (F593145), a glucocorticoid; anti-inflammatory.<br>References Kupferman, A., et al.: Arch. Ophthlmol., 640, 100 (1982), Tokunaga H., et al.: Chem. Pharm. Bull., 32, 4012 (1984),<br></p>Formule :C22H31FO4Couleur et forme :NeatMasse moléculaire :378.48Bexarotene
CAS :Produit contrôlé<p>Applications Bexarotene is a selective retinoid X receptor (RXR) agonist and an antineoplastic agent (1,2,3).<br>References (1) Boehm, M.F., et al.: J. Med. Che., 37,2930 (1994) (2) Gottardis, M.M., et al.: Cancer Res., 56, 5566 (1996) (3) Mukherjee, R., et al.: Nature, 386, 407 (1997)<br></p>Formule :C24H28O2Couleur et forme :NeatMasse moléculaire :348.48Limaprost-d3 (>90%)
CAS :Produit contrôlé<p>Applications Labelled Limaprost (L461500). Limaprost is an analog of Prostaglandin E1 with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is used as an antianginal.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tsuboi, T., et al.: Arch. Int. Pharmacodyn., 247, 89 (1980), Adaikan, P.G., et al.: Prostaglandins Med., 6, 449 (1981), Kottegoda, S.R., et al.: Prostaglandins Leukotrienes Med., 8, 343 (1982), Ishizaki, T., et al.: Chest, 85, 382 (1984),<br></p>Formule :C22H33D3O5Degré de pureté :>90%Couleur et forme :NeatMasse moléculaire :383.541(10)-Dehydro-4(5)-dihydro D-(-)-Norgestrel
Produit contrôlé<p>Applications Norgestrel (N689500) impurity.<br></p>Formule :C21H28O2Couleur et forme :NeatMasse moléculaire :312.455α-Androstanedione
CAS :Produit contrôlé<p>Applications 5α-Androstanedione is a metabolite of Androstendione (A637550). 5α-Androstanedione is an important intermediate in the conversion of Androstenedione to Androstanolone (A637540).<br>References Milewich, L., et al.: J. Steroid Chem., 16, 81 (1982); Stanczyk, F. Z., et al.: J. Steroid Biochem. Mol. Biol., 37, 129 (990);<br></p>Formule :C19H28O2Couleur et forme :NeatMasse moléculaire :288.42Betamethasone 17-Acetate
CAS :Produit contrôléFormule :C24H31FO6Couleur et forme :NeatMasse moléculaire :434.5o-Flutamide
CAS :Produit contrôlé<p>Impurity Flumazenil EP Impurity F<br>Applications o-Flutamide is an isomer of Flutamide (F598850), a nonsteroidal antiandrogen drug; antineoplastic (hormonal).<br>References Neri, et al.: Endocrinology, 91, 427 (1972), Sogani, P.C., et al.: J. Urol., 122, 640 (1979), Greenway, B.A., et al.: Br. Med. J., 316, 1935 (1998),<br></p>Formule :C11H11F3N2O3Couleur et forme :NeatMasse moléculaire :276.21(11b,16a)-9-Fluoro-11,21,21-trihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
CAS :Produit contrôléFormule :C24H31FO7Couleur et forme :Light YellowMasse moléculaire :450.504-Fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-N,β-diphenyl-benzenebutanamide
CAS :Produit contrôlé<p>Impurity Atorvastatin Diketo Amide Impurity<br>Applications An Atorvastatin intermediate. Atorvastatin is a selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Winters, R., et al.: J. Med. Chem., 36, 1735 (1993), Hagmann, W., et al.: Bioorg. Med. Chem. Lett., 10, 1975 (2000), Istvan, E., et al.: Science, 292, 1160 (2001)<br></p>Formule :C26H24FNO3Couleur et forme :White To Off-WhiteMasse moléculaire :417.476-Oxo D-(-)-Norgestrel
CAS :Produit contrôlé<p>Impurity Levonorgestrel EP Impurity J<br>Applications 6-Oxo D-(-)-Norgestrel (Levonorgestrel EP Impurity J) is an impurity of D-(-)-Norgestrel (N689510).<br></p>Formule :C21H26O3Couleur et forme :NeatMasse moléculaire :326.43(3a)-Allopregnanolone
CAS :Produit contrôlé<p>Applications (3α)-Allopregnanolone acts as a GABAA receptor positive allosteric modulator. (3α)-Allopregnanolone is a metabolite of Progesterone (P755900). (3α)-Allopregnanolone is a neuroactive steroid present in the blood and also the brain. In 2019, the US Food and Drug Administration approved (3α)-Allopregnanolone as an intravenous infusion for treating postpartum depression.<br>References Puja, G. et al.: Neuron, 4, 759 (1990); Belelli, D. et ael. Neurosteroid, 6, 565 (2006); Viapiano, M. et al.: Neurochem. Res., 23, 155 (1998);<br></p>Formule :C21H34O2Couleur et forme :White To Off-WhiteMasse moléculaire :318.49(25R)-26-Hydroxycholesterol
CAS :Produit contrôlé<p>Applications (25R)-26-Hydroxycholesterol is a desmosterol metabolite that is found in the brain. 26-Hydroxycholesterol has been used as a biomarker for carbon cycling in the northwestern Mediterranean Sea.<br>References Meljon, A., et. al.: J. Lipid Res., 53, 2469 (2012); Christodoulou, S., et. al.: Marine Chem., 113, 25 (2009)<br></p>Formule :C27H46O2Couleur et forme :NeatMasse moléculaire :402.652(6a,11b,16a)-21-(Acetyloxy)-6,9-difluoro-11,16,17-trihydroxypregna-1,4-diene-3,20-dione
CAS :Produit contrôlé<p>Applications (6α,11β,16α)-21-(Acetyloxy)-6,9-difluoro-11,16,17-trihydroxypregna-1,4-diene-3,20-dione is an impurity of Fluocinolone Acetonide, Glucocorticoid; anti-inflammatory.<br>References Sammul, et al.: J. Assoc. Off. Agric. Chem., 47, 952 (1964), Emerson, M.V., et al.: BioDrugs, 21, 245 (2007),<br></p>Formule :C23H28F2O7Couleur et forme :NeatMasse moléculaire :454.466a-Hydroxy Gestrinone
CAS :Produit contrôléFormule :C21H24O3Couleur et forme :NeatMasse moléculaire :324.419α-Fluoro-11β-hydroxy-16-β-methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2’-[4’-chloro-5’-ethylfuran-3’(2’H)-one
CAS :<p>Impurity Clobetasol Propionate EP Impurity J<br>Applications 9α-Fluoro-11β-hydroxy-16-β-methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2’-[4’-chloro-5’-ethylfuran-3’(2’H)-one (Clobetasol Propionate EP Impurity J) is an impurity in the synthesis of Clobetasol 17-Propionate (C583500), a topical corticosteroid. Glucocorticoid; anti-inflammatory.<br>References Olsen, E.A., et al.: J. Am. Acad. Dermatol., 15, 246 (1986),<br></p>Formule :C25H30ClFO4Couleur et forme :NeatMasse moléculaire :448.95Desmosterol
CAS :<p>Applications A metabolite of Cholesterol (C432501).<br>References Marx, J., et al.: Science, 294, 508 (2001), Plosch, T., et al.: J. Biol. Chem., 277, 33870 (2002), Lund, E., et al.: J .Biol. Chem., 278, 22980 (2003),<br></p>Formule :C27H44OCouleur et forme :White To Off-WhiteMasse moléculaire :384.6417-Deoxy Cortienic Acid
CAS :<p>Applications 17-Deoxy Cortienic Acid was used in the synthetic preparation of macrolactonolides, a class of potential antiinflammatory drugs.<br>References Tomaskovic, L., et al.: Bioorg. Med. Chem., 21, 321 (2013); Little, R.J., et al.: Pharma. Res., 16, 961 (1999); Manz. B., et al.: J. Steroid. Biochem., 17, 335 (1982);<br></p>Formule :C20H28O4Couleur et forme :NeatMasse moléculaire :332.434-[(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]benzoic Acid
CAS :Produit contrôlé<p>Applications 4-[(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]benzoic Acid is used in the preparation of pentamethylnaphthylmethylbenzoates as a selective retinoid X receptor ligands that induce apoptosis in leukemia cells.<br>References Boehm, M.F., et al.: J. Med. Chem., 38, 3146-55 (1995); Furmie, J.K., et al.: ChemMedChem, 7, 1551-66 (2012)<br></p>Formule :C23H26O3Couleur et forme :NeatMasse moléculaire :350.45Pregnenolone-d4
CAS :Produit contrôlé<p>Applications Pregnenolone-d4, is the labeled analogue of the Pregnenolone (P712200), which is a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens.<br>References Bjondahl, K., et al.: Med. Biol., 54, 454 (1976), Geick, A., et al.: J. Biol. Chem., 276, 14581 (2001), Johnson, D., et al.: Toxicol. Sci., 66, 16 (2002), Abe, C., et al.: Lipids, 42, 637 (2007),<br></p>Formule :C212H4H28O2Couleur et forme :Off-WhiteMasse moléculaire :320.50Norethindrone-2,2,4,6,6,10-D6
CAS :Produit contrôlé<p>Applications Isotope labelled Norethindrone (N676000), a labelled progesterone in combination with acetate used as an oral contraceptive (1,2). It is reasonably anticipated to be a human carcinogen. Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Shroff, A. et al.: Anal. Profiles Drug Subst. 1975 ; 4;268-2932. Singh, H. et al.: Am. J .Obstet. Gynecol. 1979 Oct 1;135(3):409-14<br></p>Formule :C20D6H20O2Couleur et forme :NeatMasse moléculaire :304.46Dexamethasone-d3
CAS :Produit contrôlé<p>Applications Dexamethasone-d3 is the labelled form of Dexamethasone (D298800), which is a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T-cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase.<br>References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995), Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999), Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999)<br></p>Formule :C22H26D3FO5Couleur et forme :Off-White To Light BeigeMasse moléculaire :395.485,6-trans-Vitamin D3, ~90%
CAS :Produit contrôlé<p>Impurity Cholecalciferol EP Impurity A<br>Stability Light Sensitive, Temperature Sensitive<br>Applications 5,6-trans-Vitamin D3 (Cholecalciferol EP Impurity A) is the major photoisomer of Vitamin D3 analog, as an impurity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bikle, D., et al.: Biochemistry, 25, 1545 (1986), Webb, A., et al.: J. Clin. Endocrinol. Metab., 68, 882 (1989), Baran, D., et al.: J. Cell Biochem., 50, 124 (1992), Tian, X., et al.: J. Biol. Chem., 268, 14888 (1993),<br></p>Formule :C27H44ODegré de pureté :~90%Couleur et forme :White To Light YellowMasse moléculaire :384.6420b-Dihydroprogesterone
CAS :Produit contrôlé<p>Impurity Progesterone EP Impurity C<br>Applications 20β-Dihydroprogesterone (Progesterone EP Impurity C) is an impurity of Progesterone (P755900), a steroid hormone secreted by the corpus luteum. Progesterone have various significant physiological roles, such as inducing the maturation and secretory activities of the uterine endothelium and the suppression of ovulation. Progesterone is also implicated in the etiology of breast cancer.<br>References Anderson, E., et al.: Breast Cancer Res., 4, 197 (2002), Lanari, C., et al.: Breast Cancer Res., 4, 240 (2002), Albrecht, E.D., et al.: Front. Biosci., 8, 416 (2003), Qiu, M., et al.: J. Steroid Biochem. Mol. Biol., 85, 147 (2003),<br></p>Formule :C21H32O2Couleur et forme :White To Off-WhiteMasse moléculaire :316.48
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