Stéroïdes et Dérivés
Les stéroïdes sont des composés organiques possédant une structure de quatre cycles fusionnés, connue sous le nom de noyau stéroïdien. Ce noyau peut être associé à divers groupes fonctionnels modifiant leurs propriétés et leurs fonctions biologiques. Les stéroïdes jouent un rôle clé dans la régulation des processus métaboliques et hormonaux. Ils sont utilisés en médecine pour traiter les troubles inflammatoires, les maladies auto-immunes et les déséquilibres hormonaux. De plus, certains dérivés stéroïdiens possèdent de puissantes propriétés anti-inflammatoires, comme les corticostéroïdes. Dans certaines thérapies spécifiques, ils sont utilisés pour réduire l’inflammation et soulager la douleur dans diverses maladies.
Chez CymitQuimica, nous proposons une variété de stéroïdes et de leurs dérivés pour la recherche et le développement pharmaceutique.
4949 produits trouvés pour "Stéroïdes et Dérivés"
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Calcipotriol EP Impurity H
<p>Calcipotriol EP Impurity H is an impurity found in calcipotriol EP. It is a metabolite of calcipotriol EP, which is the active ingredient in Dovonex. Calcipotriol EP Impurity H can be detected by HPLC with a retention time of 11.5 minutes and its purity can be determined by UV spectroscopy at 254 nm with a purity of >98%. Calcipotriol EP Impurity H can also be synthesized from natural or synthetic sources.</p>Formule :C54H78O5Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :807.19 g/molDefluoro atorvastatin calcium
CAS :<p>Defluoro atorvastatin calcium is a bulk drug that has been approved to be used as an adjunct to diet to reduce elevated cholesterol levels in adults. Defluoro atorvastatin calcium is the desfluoro-enantiomer of atorvastatin, which is a statin that inhibits the enzyme HMG-CoA reductase. This enzyme catalyzes the conversion of HMG-CoA to mevalonic acid, which is an early step in the synthesis of cholesterol. The fluoro group on defluoro atorvastatin calcium is not expected to have any significant effect on its potency or metabolic pathways and any impurities are not expected to have any therapeutic effect.</p>Formule :C66H70CaN4O10Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :1,119.36 g/molLevonorgestrel EP Impurity P
CAS :<p>Soluble in Chloroform & in Methanol Confirmed<br>Insoluble in Wate</p>Degré de pureté :90% minCouleur et forme :Off White or Beige SolidMasse moléculaire :312.45Difluoro atorvastatin
CAS :<p>Difluoro atorvastatin is a filtrate of atorvastatin, which is a cholesterol-lowering drug. It is synthesized by reacting butyric acid with atorvastatin in an organic solvent. The reaction solution was filtered to remove impurities and then purified by liquid chromatography. The product was characterized by diffraction and LC-MS analysis. Difluoro atorvastatin has a high purity and is suitable for further use in the preparation of pharmaceuticals.</p>Formule :C33H34F2N2O5Degré de pureté :Min. 95%Masse moléculaire :576.63 g/molAtorvastatin methyl ester
CAS :<p>Atorvastatin methyl ester is a statin drug that inhibits the synthesis of cholesterol and other lipids in the body. It is used to reduce high levels of low-density lipoprotein (LDL) cholesterol, which may lead to heart disease or stroke. Atorvastatin methyl ester has been shown to be effective in reducing the uptake of LDL cholesterol into cells by preventing the formation of LDL particles. This drug also decreases the production of biphosphate-containing phospholipids, which are essential for dendritic cell maturation. The crystalline polymorphs have been characterized by X-ray diffraction and microscopy. Impurities can be detected using ultraviolet spectroscopy, infrared spectroscopy, or nuclear magnetic resonance spectroscopy.</p>Formule :C34H37FN2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :572.67 g/mol(3R,5S)-Atorvastatin sodium salt
CAS :<p>(3R,5S)-Atorvastatin sodium salt is a synthetic compound that is used in the treatment of high cholesterol. It belongs to the class of statins, which are used for lowering blood cholesterol levels. The drug product contains at least 99% by weight of (3R,5S)-atorvastatin sodium salt. This product also has an analytical purity greater than 98%. It is metabolized via oxidation and hydroxylation to form metabolites that exhibit pharmacological activity similar to the parent molecule. (3R,5S)-Atorvastatin sodium salt is a natural product that can be found in plants such as yew trees. This drug has been shown to have niche applications in drug development and research and development.</p>Formule :C33H34FN2NaO5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :580.62 g/molFluticasone propionate EP Impurity F
CAS :<p>Fluticasone Propionate EP Impurity F is an impurity of Fluticasone Propionate. Fluticasone Propionate is a synthetic glucocorticoid used in the treatment of asthma and other allergic disorders. Impurity F is a metabolite of Fluticasone Propionate and has been detected in human plasma at low levels (5% of total fluticasone propionate). The metabolism of Fluticasone Propionate to Impurity F has been studied in rat, mouse, dog and man.<br>br>br><br>The following table summarizes the metabolic pathways that have been identified for this impurity:<br>br>br><br>Metabolism studies indicate that Impurity F is mainly metabolized by CYP3A4 to form conjugates with glucuronic acid or sulfates. It may also be hydrolyzed to form 5α-flurostan-3β,17β-d</p>Formule :C25H29F3O5SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :498.56 g/molAtorvastatin
CAS :<p>Orally active atorvastatin inhibits HMG-CoA reductase, lowers lipids, hinders SV-SMC cell growth, and can up thrombotic risk with clopidogrel.</p>Formule :C33H35FN2O5Degré de pureté :99.37% - 99.69%Couleur et forme :SolidMasse moléculaire :558.64Bexarotene
CAS :<p>Bexarotene (LGD1069) is a retinoid analogue that is used to treat the skin manifestations of cutaneous T cell lymphoma (CTCL).</p>Formule :C24H28O2Degré de pureté :99% - 99.65%Couleur et forme :White SolidMasse moléculaire :348.48Travoprost
CAS :<p>Travoprost (Fluprostenol isopropyl ester) is used to treat glaucoma and ocular hypertension,is a potent and selective FP prostaglandin receptor agonist.</p>Formule :C26H35F3O6Degré de pureté :97.39% - 99.58%Couleur et forme :Colorless OilMasse moléculaire :500.55(R)-4-((5S,7R,8R,9S,10S,12S,13R,14S,17R)-7,12-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
CAS :Degré de pureté :95%Masse moléculaire :392.5813-Ethyl-3-ethynyl-18,19-dinor-17α-pregna-3,5-dien-20-yn-17-ol(Levo Norgestrel Impurity)
CAS :Produit contrôlé<p>Impurity Levonorgestrel EP Impurity C<br>Applications 13-Ethyl-3-ethynyl-18,19-dinor-17α-pregna-3,5-dien-20-yn-17-ol (Levonorgestrel EP Impurity C) is an impurity of Levonorgestrel.<br></p>Formule :C23H28OCouleur et forme :NeatMasse moléculaire :320.476a-Hydroxy Levonorgestrel
CAS :<p>Impurity Levonorgestrel EP Impurity G<br>Applications 6α-Hydroxy Levonorgestrel (Levonorgestrel EP Impurity G) is a hydroxylated impurity of Norgestrel (N689500).<br>References Lin, Y., et al.: Biochim. Biophys. Acta, 218, 526 (1970), Smith, K., et al.: J. Steroid Biochem., 32, 445 (1989), Hu, S., et al.: Steroids, 60, 337 (1995),<br></p>Formule :C21H28O3Couleur et forme :White SolidMasse moléculaire :328.44(4S,cis)-1,1-Dimethylethyl-6-aminoethyl-2,2-dimethyl-1,3-dioxane-4-acetate
CAS :Produit contrôlé<p>Applications An impurity of Atorvastatin.<br>References Graul, A., et al.: Drugs Fut. 22, 956 (1997),<br></p>Formule :C14H27NO4Couleur et forme :NeatMasse moléculaire :273.3721-Carboxy Dexamethasone
CAS :<p>Applications 21-Carboxy Dexamethasone is a useful research chemical.<br>References Shepard, Allan R., ACS Chem. Biol., 3, 549-558(2013);<br></p>Formule :C22H27FO6Couleur et forme :White To Off-WhiteMasse moléculaire :406.4416-Methyl-17,20:20,21-bis[methylenebis(oxy)]-pregn-4-ene-3,11-dione
CAS :Produit contrôléFormule :C24H32O6Couleur et forme :NeatMasse moléculaire :416.516,7-Dihydrocanrenone
CAS :Produit contrôléFormule :C22H30O3Couleur et forme :NeatMasse moléculaire :342.47∆9,11-Dehydro-17α-cyanomethyl Estradiol
CAS :Produit contrôlé<p>Applications ∆9,11-Dehydro-17α-cyanomethyl estradiol is a metabolite of progestin dienogest (D441870), and is currently being investigated for progesterone-receptor binding, progestational, antiprogestational, estrogenic and antigonadotropic activities for the inhibition of fertility. It is also being considered a novel treatment for heavy menstrual bleeding.<br>References Oettel, M., et al.: Pharmazie, 41, 627 (1993); Kiley, J. & Shulman, L.: Int. J. Womens Health, 3, 281 (2011);<br></p>Formule :C20H23NO2Couleur et forme :NeatMasse moléculaire :309.40(16α)-16-Methyl-17,20:20,21-bis[methylenebis(oxy)]-pregna-1,4-diene-3,11-dione
CAS :Produit contrôléFormule :C24H30O6Couleur et forme :NeatMasse moléculaire :414.49Exemestane-13C,D3
CAS :Produit contrôlé<p>Applications Exemestane-13C,D3 is the labeled analogue of Exemestane (E957000), an antineoplastic (hormonal).<br>References Giudici, D., et al.: J. Steroid Biochem., 30, 391 (1988), Evans, T.R.J., et al.: Cancer Res., 52, 5933 (1992), Zilembo, N., et al.: Brit. J. Cancer, 72, 1007 (1995)<br></p>Formule :C1913CH21D3O2Couleur et forme :NeatMasse moléculaire :300.41(3aR,4R,5R,6aS)-4-Formyl-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl [1,1'-biphenyl]-4-carboxylate
CAS :Produit contrôlé<p>Applications (3aR,4R,5R,6aS)-4-Formyl-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl [1,1'-biphenyl]-4-carboxylate is an intermediate in the synthesis of Prostaglandin E2 (P838610), the most common and biologically potent of mammalian prostaglandins.<br>References Radeuchel, B., et al.: Tetrahedron. Lett., 633, 9 (1975);<br></p>Formule :C21H18O5Couleur et forme :NeatMasse moléculaire :350.3646(5E)-Calcipotriene
CAS :Produit contrôlé<p>Impurity Calcipotriol EP Impurity C<br>Stability Temperature Sensitive<br>Applications The trans-isomeric impurity of Calcipotriene (C144200) and a vitamin D3 analogue with antitumor effects.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wietrzyk, J. et al.: Anti-Cancer Drugs, 18, 447 (2007); Wietrzyk, J. et al.: Anticancer Res., 27, 3387 (2007); Filip, B. et al.: J. Ster. Biochem. Mol. Biol., 121, 399 (2010);<br></p>Formule :C27H40O3Couleur et forme :NeatMasse moléculaire :412.60rac 7-Methoxy Lasofoxifene
CAS :Produit contrôlé<p>Applications Lasofoxifene intermediate.<br>References Rosati, R., et al.: J. Med. Chem., 41, 2928 (1998),<br></p>Formule :C29H33NO2Couleur et forme :NeatMasse moléculaire :427.58Vitamin D3 b-D-Glucuronide, >90%
CAS :Produit contrôlé<p>Stability Temperature and Light Sensitive<br>Applications A metabolite of Vitamin D3.<br>References Bell, P.A., et al.: Biochem. J., et al.: 115, 663 (1969), Kumar, R.S., et al.: J. Clin. Invest., 65, 277 (1980), Shimada, K., et al.: Biol. Pharm. Bull., 19, 491 (1996),<br></p>Formule :C33H52O7Degré de pureté :>90%Couleur et forme :NeatMasse moléculaire :560.763-Oxo-4-aza-5a-androst-1-ene-17b-carboxylic Acid Methyl Ester
CAS :Produit contrôlé<p>Impurity Finasteride EP Impurity B<br>Applications 3-Oxo-4-aza-5α-αndrost-1-ene-17β-carboxylic Acid Methyl Ester (Finasteride EP Impurity B) is an impurity of Finasteride (F342000) and Dutasteride (D735000). An intermediate in the synthesis of Finasteride and Dutasteride, 5α-reductase inhibitors used for treatment of benign prostatic hyperplasia acne, seborrhea, female hirsutism, prostatitis, and prostatic carcinoma and other hyperandrogenetic related disorders. Finasteride impurity.<br>References Bakshi., et al.: J. Med. Chem., 38, 3189 (1995),<br></p>Formule :C20H29NO3Couleur et forme :White To Off-WhiteMasse moléculaire :331.45Estradiol 3-Valerate
CAS :Produit contrôlé<p>Applications Estradiols ester used in polymeric matrix for transdermal treatment of osteoporosis.<br>References Tripathi, V.N., et al.: Can. J. Animal Sci., 48, 449 (1968),<br></p>Formule :C23H32O3Couleur et forme :NeatMasse moléculaire :356.51Ciclesonide-d11 (Mixture of Diastereomers)
CAS :Produit contrôlé<p>Applications A labelled glucocorticoid microemulsion nasal preparation allergy inhibitor rhinitis.This compound is a mixture of diastereomers at the cyclohexyl acetal.<br>References Fukuoka, E., et al.: Chem. Pharm. Bull., 35, 2943 (1987), Schmitt, E., et al.: J. Pharm. Sci., 88, 291 (1999), Hancock, B., et al.: Pharm. Res., 17, 397 (2000), Hogan, S., et al.: Pharm. Res., 18, 112 (2001).<br></p>Formule :C32D11H33O7Couleur et forme :NeatMasse moléculaire :551.7611β,16α,17α,21-Tetrahydroxypregna-1,4-diene-3,20-dione-d3
Produit contrôlé<p>Applications A labelled metabolite of Budesonide (B689490), an antiinflammatory agent.<br>References Cserhati, T., et al.: J. Pharm. Biomed. Anal., 22, 25 (2000), Dilger, K., et al.: J. Clin. Pharmacol., 47, 1532 (2007), Buchwald, P., et al.: Steroids, 73, 193 (2008),<br></p>Formule :C21H25D3O6Couleur et forme :NeatMasse moléculaire :379.46Estriol 16a,17b-Diacetate
CAS :Produit contrôlé<p>Applications Estriol 16α,17β-Diacetate is a diacetate derivative of Estriol (E888960); an estrogenic metabolite considerably less potent than the hormone Estradiol (E888000).<br>References Marrian, et al.: Biochem. J., 23,1090 (1929); Huffman, et al.: J. Biol. Chem., 169, 167 (1947)<br></p>Formule :C22H28O5Couleur et forme :NeatMasse moléculaire :372.45(3aR,4R,5R,6aS)-Hexahydro-4-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]-2-oxo-2H-cyclopenta[b]furan-5-yl Ester [1,1'-Biphenyl]-4-carboxylic Acid
CAS :<p>Applications Latanoprost Enol is an impurity of Latanoprost (L177280), a prostaglandin analogue used to treat glaucoma and other degenerative diseases of the eye.<br>References Resul, B., et al.: J. Med. Chem., 36, 2242 (1993);<br></p>Formule :C31H30O5Couleur et forme :NeatMasse moléculaire :482.57Dexamethasone acetate monohydrate
CAS :<p>Dexamethasone acetate treats rheumatic issues, skin conditions, asthma, allergies, COPD, brain swelling, croup, TB adjunct.</p>Formule :C24H33FO7Couleur et forme :SolidMasse moléculaire :452.523-(N-Phenyl-N-methyl)aminoacrolein
CAS :<p>3-(N-Phenyl-N-methyl)aminoacrolein is a hydrophobic compound that has been shown to reversibly bind to serum albumin. This binding leads to a decrease in the lipid content of lipoproteins and a decrease in the rate of their metabolism. These effects are mediated by hydrophobic interactions with the hydrophobic regions of serum albumin. 3-(N-Phenyl-N-methyl)aminoacrolein also interacts with human serum albumin, which is involved in lipid transport and metabolism, and can be used as a contrast agent for X-ray diffraction studies.</p>Formule :C10H11NODegré de pureté :Min. 97 Area-%Couleur et forme :PowderMasse moléculaire :161.2 g/mol(4R)-4-[(1S,2S,5R,7R,10R,11S,14R,15R,16S)-5,16-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]pentanoic acid
CAS :Formule :C24H40O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :392.58Sodium taurodeoxycholate monohydrate
CAS :Formule :C26H46NNaO7SDegré de pureté :95%Masse moléculaire :539.73β-Hydroxy Tibolone (1mg/ml in Acetonitrile)
CAS :Produit contrôléFormule :C21H30O2Couleur et forme :Single SolutionMasse moléculaire :314.46D-Homoanalog of Triamcinolone
CAS :Produit contrôlé<p>Applications D-Homoanalog of Triamcinolone is a rearrangement product of the drug triamcinolone, an anti-inflammatory drug.<br>References Delaney, E. J.; et al.: Steroids, 59, 196 (1994)<br></p>Formule :C21H27FO6Couleur et forme :NeatMasse moléculaire :394.43Desogestrel
CAS :Produit contrôlé<p>Applications A progestogen with low androgenic potency.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Viinikka, L., et al.: Eur. J. Clin. Pharmacol., 15, 349 (1979), Bergink, E.W., et al.: J. Steroid Biochem., 14, 175 (1981)<br></p>Formule :C22H30OCouleur et forme :White To Off-WhiteMasse moléculaire :310.47(16α)-21-[(Ethoxycarbonyl)oxy]-17-hydroxy-16-methylpregna-1,4,9(11)-triene-3,20-dione
CAS :Produit contrôlé<p>Applications (16α)-21-[(Ethoxycarbonyl)oxy]-17-hydroxy-16-methylpregna-1,4,9(11)-triene-3,20-dione is an impurity of Dexamethasone (D298800), a glucocorticoid used as an anti-inflammatory agent.<br>References Spangler, M., et al.: Chromatographia, 54(5/6), 329-334 (2001);Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995)<br></p>Formule :C25H32O6Couleur et forme :NeatMasse moléculaire :428.526α-Hydroxy-21-desacetyl Deflazacort
CAS :Produit contrôlé<p>Applications The minor metabolite of Deflazacort.<br>References Bernareggi, A., et al.: J. Pharma. Biomed. Anal., 5, 177-81 (1987), Assandri, A., et al.: Xenobiotica, 13(3), 185 (1983), Martinelli, E., et al.: Drug Metab. Dispos., 7, 335 (1979),<br></p>Formule :C23H29NO6Couleur et forme :NeatMasse moléculaire :415.48Equilin-d4
CAS :Produit contrôléFormule :C182H4H16O2Couleur et forme :White SolidMasse moléculaire :272.376α-Hydroxy Budesonide
CAS :Produit contrôléFormule :C26H34O7Couleur et forme :NeatMasse moléculaire :458.5425-Hydroxy Vitamin D3 3,3'-Biotinylaminopropyl Ether
CAS :<p>Applications Vitamin D3 (V676045) analog.<br>References Roy, A., et al.: Steroids, 60, 530 (1995);<br></p>Formule :C40H65N3O4SCouleur et forme :NeatMasse moléculaire :684.0313β-Ethyl-11-methylenegon-4-en-17-one
CAS :Produit contrôlé<p>Applications Desogestrel intermediate.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bergink, E., et al.: J. Steroid Biochem., 14, 175 (1981), Phillips, A., et al.: Contraception, 36, 181 (1987)<br></p>Formule :C20H28OCouleur et forme :NeatMasse moléculaire :284.44N-Des(1,1-dimethylethyl) N-Cyclohexyl Finasteride
CAS :Produit contrôlé<p>Applications N-Des(1,1-dimethylethyl) N-Cyclohexyl Finasteride is an impurity of Finasteride (F342000); an inhibitor of 5α-reductase which is the enzyme that converts testosterone to the more potent androgen 5α-dihydrotestosterone.Also an antialopecia agent.<br>References Koronkowski, M.J., et al.: Pharmacotherapy, 13, 309 (1993); Tenover, J.L., et al.: Clin. Ther., 19, 243 (1997); McConnell, J.D., et al.: N. Engl. J. Med., 338, 557 (1998)<br></p>Formule :C25H38N2O2Couleur et forme :NeatMasse moléculaire :398.58Estradiol 3-Propyl Ether
CAS :Produit contrôléFormule :C21H30O2Couleur et forme :NeatMasse moléculaire :314.46[1S-(1α,3aBeta,4β,7aAlpha)]-4-[2-(2,5-Dihydroxyphenyl)ethyl]octahydro-1-hydroxy-7a-methyl-5H-inden-5-one
CAS :Produit contrôléFormule :C18H24O4Couleur et forme :NeatMasse moléculaire :304.38Desisobutyryl Ciclesonide
CAS :Produit contrôlé<p>Applications Preclinical profile of Ciclesonide, a novel corticosteroid for the treatment of asthma.<br>References Austin, R., et al.: Eur. Respir. J., 20, 1386 (2002), Belvisi, M.G., et al.: J. Pharmacol. Exp. Ther., 314, 568 (2005), Richter, K., et al.: J. Clin. Pharmacol., 45, 146 ( 2005).<br></p>Formule :C28H38O6Couleur et forme :White To Off-WhiteMasse moléculaire :470.60Prednicarbate
CAS :Produit contrôlé<p>Applications Topical anti-inflammatory agent. Glucocorticoid.<br>References Stache, U., et al.: Arzneim.-Forsch., 35, 1753 (1985),<br></p>Formule :C27H36O8Couleur et forme :Off-WhiteMasse moléculaire :488.5717β-Hydroxy Exemestane-d3 17-O-β-D-Glucuronide
CAS :Produit contrôlé<p>Applications 17β-Hydroxy Exemestane 17-O-β-D-Glucuronide is the glucuronidated conjugate of the hydroxy metabolite of Exemestane (E957000).<br>References Sun, D. et al.: Pharmacogen. Genom., 20, 575 (2010);<br></p>Formule :C26H31D3O8Couleur et forme :NeatMasse moléculaire :477.563-epi-25-Hydroxy Vitamin D3
CAS :<p>Stability Light Sensitive, Temperature Sensitive<br>Applications The epimer metabolite of Calcifediol or 25-hydroxyvitamin D3 (C125700).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sakaki, T., et al.: Eur. J. Biochem., 267, 6158 (2000), Kamao, M., et al.: J. Biol. Chem., 278, 1463 (2003),<br></p>Formule :C27H44O2Couleur et forme :NeatMasse moléculaire :400.641-(2,4-Dihydroxyphenyl)-2-(4-hydroxyphenyl)propan-1-one
CAS :Produit contrôlé<p>Applications 1-(2,4-Dihydroxyphenyl)-2-(4-hydroxyphenyl)propan-1-one is an antioxidant and also has anti cancer effects on human breast cancer MCF-7 cells and Hep3B human hepatocellular carcinoma cells.<br>References Choi, Eun Jeong, et al.: Mol. Med. Rep., 9(1), 328-332 (2014);Choi, Eun Jeong, et al.: Onco.Lett., 6(6), 1784-1788 (2013);Choi, Eun Jeong, et al.: Inter. J.of Mol. Med., 31(3), 726-730 (2013)<br></p>Formule :C15H14O4Couleur et forme :NeatMasse moléculaire :258.27Dexamethasone b-D-Glucuronide Sodium (>90%)
CAS :Produit contrôlé<p>Applications Sodium salt of Dexamethasone β-D-Glucuronide is a potential prodrug for colonic delivery of the antiinflammatory corticosteroid Dexamethasone.<br>References Fotsis, T., et al.: J. Steroid Biochem., 14, 457 (1981), Choi, M., et al.: Steroids, 65, 54 (2000); Haeberlin, B. et al.: Pharm Res., 10, 1553 (1993);<br></p>Formule :C28H36FNaO11Couleur et forme :NeatMasse moléculaire :590.57Tasimelteon
CAS :<p>Applications Tasimelteon is a novel drug, used in the treatment of non-24 hour sleep-wake disorder. It helps to correct the circadian rhythm disorder often seen in patients who are visually impaired.<br>References Lahon, J. et al.: World. J. Pharm. Res., 3, 1521 (2014);<br></p>Formule :C15H19NO2Couleur et forme :NeatMasse moléculaire :245.31696b-Hydroxylevonorgestrel
CAS :<p>Impurity Levonorgestrel EP Impurity H<br>Applications 6β-Hydroxylevonorgestrel (Levonorgestrel EP Impurity H) is an impurity from the synthesis of Levonorgestrel (N689510), an oral contraceptive.<br>References Hu. S.H., et al.: Steroids., 63, 88 (1998); Nash, H.A., et al.: J. Pharma. Sci., 93, 2420 (2004); Choudhary, M.I., et al.: Natural. Prod. Res., 20, 1074 (2006);<br></p>Formule :C21H28O3Couleur et forme :White To Light YellowMasse moléculaire :328.45a-Epoxyabiraterone Acetate
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications α-Epoxyabiraterone Acetate is an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.<br>References Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389(2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005)<br></p>Formule :C26H33NO3Couleur et forme :NeatMasse moléculaire :407.55Tetrahydrocortisol 21-Acetate
CAS :Produit contrôlé<p>Applications Cortisol derivative. A potential corticoid metabolite.<br>References Okihara, R. et al.; Chem. Pharm. Bull. 58, 344 (2010); Hosoda, H. et al.; Chem. Pharm. Bull. 32, 4023 (1984)<br></p>Formule :C23H36O6Couleur et forme :NeatMasse moléculaire :408.536-Hydroxymethyl Exemestane
CAS :Produit contrôlé<p>Applications A potential metabolite of Exemestane (E957000).<br>References Buzzetti, F., et al.: Steroids, 58, 527 (1993),<br></p>Formule :C20H24O3Couleur et forme :NeatMasse moléculaire :312.40b-Estradiol 17-Acetate
CAS :Produit contrôlé<p>Applications Protected Estradiol. Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References Miilunpohja, M., et al.: J. Steroid Biochem. Mol. Biol., 100, 59 (2006), Ikonomou, M., et al.: Environ. Toxicol. Chem., 27, 243 (2008),<br></p>Formule :C20H26O3Couleur et forme :NeatMasse moléculaire :314.421,2-Dihydro Triamcinolone
CAS :Produit contrôlé<p>Applications 1,2-Dihydro Triamcinolone is a derivative of Triamcinolone (T767165), a glucocorticoid, antiasthmatic (inhalant); antiallergic (nasal).<br>References Florey, K., et al.: Anal. Profiles Drug Subs., 1, 397 (1972); Bernstein, I.L., et al.: Chest, 81, 20 (1982);<br></p>Formule :C21H29FO6Couleur et forme :NeatMasse moléculaire :396.45Tixocortol
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Tixocortol is an anti-inflammatory agent. Tixocortol is used in fluorescent chemoaffinity labeling.<br>References Torossian, D.R., et al.: Arzneim.-Forsch., 31, 453 (1981),<br></p>Formule :C21H30O4SCouleur et forme :NeatMasse moléculaire :378.53Fluocinolone Acetonide-13C3
CAS :Produit contrôléFormule :C2113C3H30F2O6Couleur et forme :NeatMasse moléculaire :455.47Finasteride Carboxaldehyde
CAS :Produit contrôlé<p>Applications A metabolite of Finasteride (F342000) in human bile (M2 metabolite).<br>References Faller, B., et al.: Biochemistry, 32, 5705 (1993), Carlin, J.R., Drug Metab. Dispos., 25, 100 (1997), Bergman, E., et al.: Eur. J. Pharm. Sci., 29, 205 (2006),<br></p>Formule :C23H34N2O3Couleur et forme :NeatMasse moléculaire :386.53(11β)-9-Fluoro-11,21-dihydroxy-16-methyl-pregna-1,4,16-triene-3,20-dione
CAS :Produit contrôlé<p>Applications (11β)-9-Fluoro-11,21-dihydroxy-16-methyl-pregna-1,4,16-triene-3,20-dione is a derivative of Dexamethasone (D298800), an anti-inflammatory glucocorticoid.<br>References Kodelja, V., et al.: J. Immunol., 160, 1411 (1998), Metselaar, J., et al.: Arthritis Rheum., 48, 2059 (2003), Buttgereit, F., et al.: Arthritis Rheum., 50, 3408 (2004), Martinez, F., et al.: Front Biosci., 13, 453 (2008),<br></p>Formule :C22H27FO4Couleur et forme :WhiteMasse moléculaire :374.456a-9-Difluoroprednisolone-17-Carboxylate
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications 6α-9-Difluoroprednisolone-17-Carboxylate is an impurity of 6α,9α-Difluoroprednisolone (D446290), shown to increase metastases and increase glucocorticoid activity in C57/BL6 mice.<br>References Albert, D., Zeidman, I.: Cancer Res., 22, 1297 (1962)<br></p>Formule :C20H24F2O5Couleur et forme :NeatMasse moléculaire :382.46b-Chloro-17-acetoxy Progesterone
CAS :Produit contrôlé<p>Applications Progesterone (P755900) impurity.<br>References Liang, T., et al.: Biol. Chem., 256, 7998 (1981), Bratoeff, E., et al.: J. Steroid Biochem. Mol. Biol., 111, 275 (2008),<br></p>Formule :C23H31ClO4Couleur et forme :NeatMasse moléculaire :406.94317α-Hydroxyprogesterone Valerate
CAS :Produit contrôlé<p>Applications 17α-Hydroxy-progesterone Valerate acts as a synthetic Progesterone (P755900) reducing the chance of pre-term birth in women. Progesterone is a steroid hormone produced by the corpus luteum. Induces maturation and secretory activity of the uterine endothelium; suppresses ovulation<br>References Anderson, E., et al.: Breast Cancer Res., 4, 197 (2002), Lanari, C., et al.: Breast Cancer Res., 4, 240 (2002), Albrecht, E.D., et al.: Front. Biosci., 8, 416 (2003), Qiu, M., et al.: J. Steroid Biochem. Mol. Biol., 85, 147 (2003),<br></p>Formule :C26H38O4Couleur et forme :NeatMasse moléculaire :414.58E-Ospemifene
CAS :Produit contrôlé<p>Applications E-Ospemifene is the E-isomer of Ospemifene (O703000) and is useful for lowering serum cholesterol. It acts as a antiatherosclerotic and is also estrogen-like.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sodervall, M., et al.: PCT Int. Appl. WO 9942427 A1 19990826. Aug 26, 1999<br></p>Formule :C24H23ClO2Couleur et forme :NeatMasse moléculaire :378.8920-Hydroxydexamethasone
CAS :Produit contrôléFormule :C22H31FO5Couleur et forme :NeatMasse moléculaire :394.483-O-Benzyl Estriol
CAS :Produit contrôlé<p>Applications Protected Estriol.<br>References Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),<br></p>Formule :C25H30O3Couleur et forme :NeatMasse moléculaire :378.502-Hydroxy Estradiol 6-N3-Adenine
CAS :Produit contrôlé<p>Applications 2-Hydroxy Estradiol 6-N3-Adenine is a depurinating adduct that is created by the interaction of specific metabolites of estrogens in the body with DNA. Unfortunately, these adducts are endogeneous initiators of various human cancers, such as breast & prostate.<br>References Yang, L., et al.: Prostate, 69, 41 (2009); Zahid, M., et al.: Chem. Res. Toxicol., 19, 164 (2006); Zhang, Y., et al.: Metabol. Clin. Exp., 56, 887 (2007)<br></p>Formule :C23H27N5O3Couleur et forme :NeatMasse moléculaire :421.493-Oxo-4-aza-5-androstene-17β-carboxylic Acid
CAS :Produit contrôléFormule :C19H27NO3Couleur et forme :NeatMasse moléculaire :317.42Equilenin-d3
CAS :Produit contrôlé<p>Applications Isotope labelled Equilenin (E592400), which is a naturally occuring estrogenic steroidal hormone (1,2) isolated from urine of pregnant mares (3). Not found in human urine. Component of conjugated estrogenic hormones. Estrogen. This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Corbellini, A. et L.: Farmaco Sci. 1964 Nov;19:913-22.2. Stein, R. et al.: Tetrahedron 1970 Apr;26(8):1917-33.<br></p>Formule :C182H3H15O2Couleur et forme :White To Light BrownMasse moléculaire :269.3517β-Dihydro Equilin-16,16,17-d3
CAS :Produit contrôlé<p>Applications A labelled metabolite of Equilin (E592800).<br>References Enmark, E., et al.: J. Clin. Endocrinol. Metab., 82, 4258 (1997), Wang, Z., et al.: J. Med. Chem., 43, 2419 (2000), Jiang, X., et al.: Steroids, 71, 334 (2006),<br></p>Formule :C182H3H17O2Couleur et forme :NeatMasse moléculaire :271.37δ6-Fulvestrant
CAS :Produit contrôlé<p>Impurity Fulvestrant Impurity E;<br>Applications Fulvestrant (F862500) impurity E.<br></p>Formule :C32H45F5O3SCouleur et forme :NeatMasse moléculaire :604.75Dexamethasone Acetate Impurity E
CAS :<p>Applications Dexamethasone Acetate Impurity E is a pregn-4-ene derivative used in the preparation of antiallergic and antiinflammatory drugs.<br>References Nedelec, L., et al.: Ger. Offen. (1978)<br></p>Formule :C24H33FO6Couleur et forme :NeatMasse moléculaire :436.51Atorvastatin-d5 tert-Butyl Ester
CAS :Produit contrôlé<p>Applications Atorvastatin-d5 tert-Butyl Ester is the labeled analogue of Atorvastatin tert-Butyl Ester (A791740), an impurity arising in the synthesis of Atorvastatin (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)<br></p>Formule :C37H38D5FN2O5Couleur et forme :NeatMasse moléculaire :619.78Deflazacort-d3 (Major)
CAS :Produit contrôléFormule :C25H28D3NO6Couleur et forme :NeatMasse moléculaire :444.546β-Hydroxymethylandrosta-1,4-diene-3,17-dione
CAS :Produit contrôléFormule :C20H26O3Couleur et forme :White To Off-WhiteMasse moléculaire :314.42Equilin 3-O-β-D-Glucuronide Sodium Salt
CAS :Formule :C24H27NaO8Couleur et forme :NeatMasse moléculaire :466.46Testosterone-16,16,17-d3 Benzoate
CAS :Produit contrôléFormule :C26H29D3O3Couleur et forme :NeatMasse moléculaire :395.5616α-Hydroxypregna-4,9(11)-diene-3,20-dione
Produit contrôlé<p>Applications 16α-Hydroxypregna-4,9(11)-diene-3,20-dione is an intermediate in the synthesis of 16-Hydroxycorticosterone 20-Hydroxy-21-Acid (H918430), an oxidized derivative of corticosterone (C695700).<br>References Allen, G.R., et al.: J. Am. Chem. Soc., 81, 4968 (1959);<br></p>Formule :C21H28O3Couleur et forme :NeatMasse moléculaire :328.4521-Butyryloxy Budesonide
<p>Applications 21-Butyryloxy Budesonide is a derivative of Budesonide (B689490), a non-halogenated glucocorticoid related to triamcinolone hexacetonide.<br>References Ryrfeldt., A., et a.: J. Steroid Biochem., 10, 317 (1979); Roth, G., et al.: J. Pharm. Sci., 69, 766 (1980); Clissold, S.P., et al.: Drugs, 28, 485 (1984)<br></p>Formule :C29H40O7Couleur et forme :NeatMasse moléculaire :500.62Digitoxigenin Mono-β-D-digitoxoside
CAS :Produit contrôléFormule :C29H44O7Couleur et forme :White To Off-WhiteMasse moléculaire :504.66Testosterone-13C
CAS :Produit contrôléFormule :C1813CH28O2Couleur et forme :NeatMasse moléculaire :289.426β,17α-Dihydroxyprogesterone
CAS :Produit contrôléFormule :C21H30O4Couleur et forme :NeatMasse moléculaire :346.466-Dehydro Nandrolone Acetate
CAS :Produit contrôléFormule :C20H26O3Couleur et forme :NeatMasse moléculaire :314.42Boldione (1 mg/ml in Acetonitrile)
CAS :Produit contrôléFormule :C19H24O2Couleur et forme :Single SolutionMasse moléculaire :284.396-Deschloro Cyproterone Acetate
CAS :Produit contrôlé<p>(1β,2β)-17-(Acetyloxy)-1,2-dihydro-3'H-cyclopropa[1,2]pregna<br>-1,4,6-triene-3,20-dione; 17-Hydroxy-1 ,2 -methylenepregna<br>-4,6-diene-3,20-dione Acetate; Cyproterone Acetate EP<br>Impurity A<br></p>Formule :C24H30O4Couleur et forme :NeatMasse moléculaire :382.4934'-Nitro-3'-(trifluoromethyl)acetanilide
CAS :<p>Applications 4’-Nitro-3’-(trifluoromethyl)acetanilide is a metabolite of the nonsteroidal antiandrogen drug, Flutamide (F598850).<br>References Kang, P. et al.: Drug Metab. Dispos., 36, 1425 (2008); Takashima, E. et al.: Biol. Pharmac. Bull., 26, 1455 (2003); Katchen, B. et al.: J. Invest. Dermatol., 66, 379 (1976);<br></p>Formule :C9H7F3N2O3Couleur et forme :NeatMasse moléculaire :248.162-Methyl Ethynyl Estradiol
CAS :Produit contrôlé<p>Impurity Ethinylestradiol EP Impurity M<br>Applications 2-Methylethynylestradiol (Ethinylestradiol EP Impurity M) is a 17α-ethynyl steroid. 2-Methylethynylestradiol is an impurity of Ethynylestradiol (E685100).<br></p>Formule :C21H26O2Couleur et forme :NeatMasse moléculaire :310.43Testosterone-16,16,17-d3 3-Phenylpropionate
CAS :Produit contrôlé<p>Applications Testosterone-16,16,17-d3 17-Phenylpropionate, is the labeled analogue of Testosterone 17-Phenylpropionate (T155150), a Testosterone ester being misused by athletes in an attempt to improve sports performance. It can also be used as a therapy in glucocorticoid-treated patients to increase the circulating testosterone concentration.<br>References Shackleton, C. H. L., et al.: Steroids, 62 (7), 523 (1997); Reid, I. R., et al.: Archives Internal Med., 156 (11), 1173 (1996);<br></p>Formule :C28H33D3O3Couleur et forme :NeatMasse moléculaire :423.60
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