Stéroïdes et Dérivés
Les stéroïdes sont des composés organiques possédant une structure de quatre cycles fusionnés, connue sous le nom de noyau stéroïdien. Ce noyau peut être associé à divers groupes fonctionnels modifiant leurs propriétés et leurs fonctions biologiques. Les stéroïdes jouent un rôle clé dans la régulation des processus métaboliques et hormonaux. Ils sont utilisés en médecine pour traiter les troubles inflammatoires, les maladies auto-immunes et les déséquilibres hormonaux. De plus, certains dérivés stéroïdiens possèdent de puissantes propriétés anti-inflammatoires, comme les corticostéroïdes. Dans certaines thérapies spécifiques, ils sont utilisés pour réduire l’inflammation et soulager la douleur dans diverses maladies.
Chez CymitQuimica, nous proposons une variété de stéroïdes et de leurs dérivés pour la recherche et le développement pharmaceutique.
4949 produits trouvés pour "Stéroïdes et Dérivés"
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13β-Ethyl-11-methylenegon-4-en-17-one
CAS :Produit contrôlé<p>Applications Desogestrel intermediate.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bergink, E., et al.: J. Steroid Biochem., 14, 175 (1981), Phillips, A., et al.: Contraception, 36, 181 (1987)<br></p>Formule :C20H28OCouleur et forme :NeatMasse moléculaire :284.44Desisobutyryl Ciclesonide
CAS :Produit contrôlé<p>Applications Preclinical profile of Ciclesonide, a novel corticosteroid for the treatment of asthma.<br>References Austin, R., et al.: Eur. Respir. J., 20, 1386 (2002), Belvisi, M.G., et al.: J. Pharmacol. Exp. Ther., 314, 568 (2005), Richter, K., et al.: J. Clin. Pharmacol., 45, 146 ( 2005).<br></p>Formule :C28H38O6Couleur et forme :White To Off-WhiteMasse moléculaire :470.607α-Acetylthio-17α-ethoxymethyl Testosterone
CAS :Produit contrôléFormule :C24H36O4SCouleur et forme :NeatMasse moléculaire :420.611-Dehydro Aldosterone
CAS :Produit contrôléFormule :C21H26O5Couleur et forme :NeatMasse moléculaire :358.43Tasimelteon
CAS :<p>Applications Tasimelteon is a novel drug, used in the treatment of non-24 hour sleep-wake disorder. It helps to correct the circadian rhythm disorder often seen in patients who are visually impaired.<br>References Lahon, J. et al.: World. J. Pharm. Res., 3, 1521 (2014);<br></p>Formule :C15H19NO2Couleur et forme :NeatMasse moléculaire :245.3169Estradiol 17-Valerate-d9
CAS :Produit contrôlé<p>Applications Labelled Estradiol (E888000) derivative. An estrogen.<br>References Salole, E.G., et al.: Anal. Profiles Drug Subs., 15, 283 (1986), Lievertz, R.W., et al.: Am. J. Obstet. Gynecol., 156, 1289 (1987),<br></p>Formule :C23H23D9O3Couleur et forme :NeatMasse moléculaire :365.55Testosterone Undecanoate-d21
CAS :Produit contrôléFormule :C30H27D21O3Couleur et forme :Off-WhiteMasse moléculaire :477.846b-Hydroxylevonorgestrel
CAS :<p>Impurity Levonorgestrel EP Impurity H<br>Applications 6β-Hydroxylevonorgestrel (Levonorgestrel EP Impurity H) is an impurity from the synthesis of Levonorgestrel (N689510), an oral contraceptive.<br>References Hu. S.H., et al.: Steroids., 63, 88 (1998); Nash, H.A., et al.: J. Pharma. Sci., 93, 2420 (2004); Choudhary, M.I., et al.: Natural. Prod. Res., 20, 1074 (2006);<br></p>Formule :C21H28O3Couleur et forme :White To Light YellowMasse moléculaire :328.45Fulvestrant 17-Ketone
CAS :Produit contrôlé<p>Applications Fulvestrant 17-Ketone, is an impurity of Fulvestrant (F862500), a novel steroidal estrogen antagonist reported to lack any partial agonist activity. Antineoplastic (hormonal).<br>References Wakeling, A.E., et al.: Cancer Res., 51, 3867 (1991), Howell, A., et al.: Br. J. Cancer, 74, 300 (1996), Robertson, J.F., et al.: Cancer Res., 61, 6739 (2001),<br></p>Formule :C32H45F5O3SCouleur et forme :NeatMasse moléculaire :604.756-Hydroxymethyl Exemestane
CAS :Produit contrôlé<p>Applications A potential metabolite of Exemestane (E957000).<br>References Buzzetti, F., et al.: Steroids, 58, 527 (1993),<br></p>Formule :C20H24O3Couleur et forme :NeatMasse moléculaire :312.4018-Methyl Mestranol
CAS :Produit contrôlé<p>Applications Mestranol (M258755) derivative. It is used as contraceptive.<br>References Cullen, L.F., et al.: J. Pharma. Sci., 57, 1857 (1968),<br></p>Formule :C22H28O2Couleur et forme :NeatMasse moléculaire :324.464β-Hydroxy Cholesterol
CAS :Produit contrôlé<p>Applications A metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker.<br>References Breuer, O., et al.: J. Lipid Res., 36, 2275 (1995), Pikuleva, I., et al.: J. Biol. Chem., 273, 18153 (1998), Chawla, A., et al.: Science, 294, 1866 (2001), Bodin, K., et al.: J. Biol. Chem., 276, 38685 (2001),<br></p>Formule :C27H46O2Couleur et forme :White To Light BeigeMasse moléculaire :402.65b-Estradiol 17-Acetate
CAS :Produit contrôlé<p>Applications Protected Estradiol. Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References Miilunpohja, M., et al.: J. Steroid Biochem. Mol. Biol., 100, 59 (2006), Ikonomou, M., et al.: Environ. Toxicol. Chem., 27, 243 (2008),<br></p>Formule :C20H26O3Couleur et forme :NeatMasse moléculaire :314.42Tixocortol
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Tixocortol is an anti-inflammatory agent. Tixocortol is used in fluorescent chemoaffinity labeling.<br>References Torossian, D.R., et al.: Arzneim.-Forsch., 31, 453 (1981),<br></p>Formule :C21H30O4SCouleur et forme :NeatMasse moléculaire :378.53Dexamethasone 17-Propionate
CAS :Produit contrôlé<p>Applications A Dexamethasone Dipropionate metabolite.<br>References Miyachi, Y., et al.: Steroids, 52, 137 (1988), Soh H., et al.: Brit. J. dermatol., 125, 73 (1991), Civiale, C., et al.: J. Ocul. Pharmacol., Thera., 20, 75 (2004),<br></p>Formule :C25H33FO6Couleur et forme :NeatMasse moléculaire :448.526b-Chloro-17-acetoxy Progesterone
CAS :Produit contrôlé<p>Applications Progesterone (P755900) impurity.<br>References Liang, T., et al.: Biol. Chem., 256, 7998 (1981), Bratoeff, E., et al.: J. Steroid Biochem. Mol. Biol., 111, 275 (2008),<br></p>Formule :C23H31ClO4Couleur et forme :NeatMasse moléculaire :406.9432,5-Bis(trifluoromethyl)aniline
CAS :Produit contrôlé<p>Applications 2,5-Bis(trifluoromethyl)aniline is a haloalkul substituted aniline used in the preparation of anti-benign prostatic hyperplasia drug, Dutasteride (D735000).<br>References Liang, Y. et al.: Jil. Dax. Xueb. Lixeub., 45, 1035 (2007);<br></p>Formule :C8H5F6NCouleur et forme :ColourlessMasse moléculaire :229.127-[9-[[9-[(4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17β
Produit contrôlé<p>Applications Fulvestrant (F862500) impurity C.<br></p>Formule :C41H65F5O4S2Couleur et forme :NeatMasse moléculaire :781.072-Hydroxy Atorvastatin Lactone
CAS :Produit contrôlé<p>Impurity Atorvastatin 2-Hydroxy Lactone<br>Stability Hygroscopic<br>Applications A metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br></p>Formule :C33H33FN2O5Couleur et forme :Off White SolidMasse moléculaire :556.62Mexrenone
CAS :Produit contrôlé<p>Applications Mexrenone is an impurity of eplerenon (E588775). Eplerenone is a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.<br>References de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (2001), Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (2004), Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (2005),<br></p>Formule :C24H32O5Couleur et forme :Off-WhiteMasse moléculaire :400.507917β-Dihydro Equilin-16,16,17-d3
CAS :Produit contrôlé<p>Applications A labelled metabolite of Equilin (E592800).<br>References Enmark, E., et al.: J. Clin. Endocrinol. Metab., 82, 4258 (1997), Wang, Z., et al.: J. Med. Chem., 43, 2419 (2000), Jiang, X., et al.: Steroids, 71, 334 (2006),<br></p>Formule :C182H3H17O2Couleur et forme :NeatMasse moléculaire :271.37Betamethasone 21-Acetate
CAS :Produit contrôlé<p>Applications Betamethasone acetate (BA) is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties which can be used in treatment of asthma and itching.<br>References Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001), Seidler, J., et al.: J. Med. Chem., 46, 4477 (2003), Alsenz, J., et al.: J. Pharm. Sci., 96, 1748 (2007),<br></p>Formule :C24H31FO6Couleur et forme :WhiteMasse moléculaire :434.50Bexarotene-13C4
CAS :Produit contrôlé<p>Applications Labelled Bexarotene (B336750). Used as an antineoplastic. A selective retinoid X receptor (RXR) agonist.<br>References Boehm, M.F., et al.: J. Med. Che., 37,2930 (1994), Gottardis, M.M., et al.: Cancer Res., 56, 5566 (1996), Mukherjee, R., et al.: Nature, 386, 407 (1997), Miller, V.A., et al.: J. Clin. Oncol., 15, 790 (1997)<br></p>Formule :C4C20H28O2Couleur et forme :NeatMasse moléculaire :352.45Dexamethasone Acetate Impurity E
CAS :<p>Applications Dexamethasone Acetate Impurity E is a pregn-4-ene derivative used in the preparation of antiallergic and antiinflammatory drugs.<br>References Nedelec, L., et al.: Ger. Offen. (1978)<br></p>Formule :C24H33FO6Couleur et forme :NeatMasse moléculaire :436.51Atorvastatin-d5 tert-Butyl Ester
CAS :Produit contrôlé<p>Applications Atorvastatin-d5 tert-Butyl Ester is the labeled analogue of Atorvastatin tert-Butyl Ester (A791740), an impurity arising in the synthesis of Atorvastatin (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)<br></p>Formule :C37H38D5FN2O5Couleur et forme :NeatMasse moléculaire :619.78Deflazacort-d3 (Major)
CAS :Produit contrôléFormule :C25H28D3NO6Couleur et forme :NeatMasse moléculaire :444.54Equilin 3-O-β-D-Glucuronide Sodium Salt
CAS :Formule :C24H27NaO8Couleur et forme :NeatMasse moléculaire :466.46Cortisol-D4 21-Sulfate Potassium Salt
CAS :Produit contrôlé<p>Applications Labelled Cortisol-d4 21-Sulfate (C696320). Cortisol 21-Sulfate is a phase II metabolite of Cortisol (H714615).<br>References Spielgelhalder, B., et al.: J. Steroid Biochem., 7, 749 (1976), Vanluchene, E., et al.: J. Chromatogr., 456, 175 (1988), Choi, M., et al.: Steroids, 65, 54 (2000),<br></p>Formule :C21H25D4KO8SCouleur et forme :NeatMasse moléculaire :484.646b-Chloro-7a-hydroxy-6,7-dihydro Cyproterone Acetate
CAS :Produit contrôlé<p>(1β,2β,6β-7α)-17-(Acetyloxy)-6-chloro-1,2-dihydro-7-hydroxy<br>-3'H-cyclopropa[1,2]pregna-1,4-diene-3,20-dione; 6β-Chloro<br>-1β,2β-dihydro-7α,17-dihydroxy-3'Hcyclopropa[1,2]pregna-1,4-diene-3,20-dione 17-Acetate;<br>Cyproterone Acetate EP Impurity G</p>Formule :C24H31ClO5Couleur et forme :NeatMasse moléculaire :434.953(3(α))-Allopregnanolone 3-(β)-DGlucuronide
CAS :Produit contrôlé<p>Applications (3α)-Allopregnanolone 3-β-D-Glucuronide is the glucuronide conjugate of (3α)-Allopregnanolone (A547100), metabolite of progesterone and potent positive modulator of GABAA receptors.<br>References Martin, F. et al.: LJ Steroid Biochem., 6, 1339 (1975); Lin, M.T. et al.: Steroids, 32, 547 (1978);<br></p>Formule :C27H42O8Couleur et forme :NeatMasse moléculaire :494.6221-Butyryloxy Budesonide
<p>Applications 21-Butyryloxy Budesonide is a derivative of Budesonide (B689490), a non-halogenated glucocorticoid related to triamcinolone hexacetonide.<br>References Ryrfeldt., A., et a.: J. Steroid Biochem., 10, 317 (1979); Roth, G., et al.: J. Pharm. Sci., 69, 766 (1980); Clissold, S.P., et al.: Drugs, 28, 485 (1984)<br></p>Formule :C29H40O7Couleur et forme :NeatMasse moléculaire :500.6217-Hydroxypregn-5-ene-3,20-dione
CAS :Produit contrôlé<p>Applications 17-Hydroxypregn-5-ene-3,20-dione is used in the synthesis of physiologically active steroid esters and spirolactones that functions as potential aldosterone antagonists.<br>References Seletskii, B. M., et al.: Croat. Chem. Acta. , 58, 699 (1986)<br></p>Formule :C21H30O3Couleur et forme :NeatMasse moléculaire :330.46Testosterone-13C
CAS :Produit contrôléFormule :C1813CH28O2Couleur et forme :NeatMasse moléculaire :289.426β,17α-Dihydroxyprogesterone
CAS :Produit contrôléFormule :C21H30O4Couleur et forme :NeatMasse moléculaire :346.4617α-Hydroxyprogesterone Heptanoate
CAS :<p>Applications 17α-Hydroxyprogesterone Heptanoate can be used in therapeutic use and biological study of pharmaceutical compounds and methods of use thereof for treating gender-biased immune disorders.<br>References Stoloff, G., et al.: PCT Int. Appl. WO 2016005599 A1 20160114 (2016)<br></p>Formule :C28H42O4Couleur et forme :NeatMasse moléculaire :442.636-Dehydro Nandrolone Acetate
CAS :Produit contrôléFormule :C20H26O3Couleur et forme :NeatMasse moléculaire :314.42Epoxy Metradiene
CAS :Produit contrôlé<p>Applications Epoxy Metradiene is an impurity from synthesis of Fluorometholone (F593145),a glucocorticoid; anti-inflammatory.<br>References Kupferman, A., et al.: Arch. Ophthlmol., 640, 100 (1982); Tokunaga H., et al.: Chem. Pharm. Bull., 32, 4012 (1984);<br></p>Formule :C22H28O4Couleur et forme :NeatMasse moléculaire :356.4620-Dihydroprogesterone Acetate
CAS :Produit contrôlé<p>Impurity Progesterone EP Impurity E<br>Applications 20-Dihydroprogesterone Acetate (Progesterone EP Impurity E) is an analogue of Progesterone (P755900), a steroid used in cardiovascular and menopausal studies.<br>References Grodstein, F. et al.: New. Eng. J. Med., 335, 453 (1996); Cushman, M. et al.: Circulation, 100, 717 (1999);<br></p>Formule :C23H34O3Couleur et forme :NeatMasse moléculaire :358.51Boldione (1 mg/ml in Acetonitrile)
CAS :Produit contrôléFormule :C19H24O2Couleur et forme :Single SolutionMasse moléculaire :284.396-Deschloro Cyproterone Acetate
CAS :Produit contrôlé<p>(1β,2β)-17-(Acetyloxy)-1,2-dihydro-3'H-cyclopropa[1,2]pregna<br>-1,4,6-triene-3,20-dione; 17-Hydroxy-1 ,2 -methylenepregna<br>-4,6-diene-3,20-dione Acetate; Cyproterone Acetate EP<br>Impurity A<br></p>Formule :C24H30O4Couleur et forme :NeatMasse moléculaire :382.4932-Methyl Ethynyl Estradiol
CAS :Produit contrôlé<p>Impurity Ethinylestradiol EP Impurity M<br>Applications 2-Methylethynylestradiol (Ethinylestradiol EP Impurity M) is a 17α-ethynyl steroid. 2-Methylethynylestradiol is an impurity of Ethynylestradiol (E685100).<br></p>Formule :C21H26O2Couleur et forme :NeatMasse moléculaire :310.4325-Hydroxy Cholesterol-d6
CAS :Produit contrôlé<p>Applications 25-Hydroxy Cholesterol-d6, is the labeled analogue of 25-Hydroxy Cholesterol (H918030), which is an oxygenated derivative of Cholesterol (C432501); an oxysterol. An inhibitor of human immunodeficiency virus replication in vitro. It also induces apoptosis in human monocytic cell lines as well as inducing apoptosis in CEM cells associated with negative regulation of c-Myc.<br>References Aupeix, K. et al.: Immunobiology, 194, 415 (1995); Moog, C. et al.: Antivir. Chem, Chemother., 9, 491 (1998); Ayala-Torres, S. et al.: Exp. Cell Res., 246, 193 (1999);<br></p>Formule :C272H6H40O2Couleur et forme :NeatMasse moléculaire :408.69Estratetraenol
CAS :Produit contrôlé<p>Applications A steroid produced by females having pheromone activities.<br>References Kotiyan, P., et al.: J. Pharm. Biomed. Anal., 22, 667 (2000), Bensafi, M., et al.: Behaviour. Brain Res., 152, 11 (2004), Zhu, B., et al.: Endocrinol., 147, 4132 (2006), Bellavance, E., et al.: J. Med. Chem., 52, 7488 (2009),<br></p>Formule :C18H22OCouleur et forme :NeatMasse moléculaire :254.374-Methylestrone
CAS :Produit contrôlé<p>Applications 4-Methylestrone is an intermediate in the synthesis of 4-substituted estrone and estradiol derivatives with inhibitory activities towards steroid sulfatase as a target for therapeutic intervention of treating breast cancer.<br>References Numazawa, M., et al.: J. Steroid. Biochem. Molec. Biol., 96, 51 (2005);<br></p>Formule :C19H24O2Couleur et forme :NeatMasse moléculaire :284.39Testosterone Oleate
CAS :Produit contrôléFormule :C37H60O3Couleur et forme :NeatMasse moléculaire :552.87Betamethasone 17-Propionate 21-Mesylate
CAS :<p>Impurity Clobetasol Propionate EP Impurity I<br>Stability Hygroscopic<br>Applications Betamethasone 17-Propionate 21-Mesylate (Clobetasol Propionate EP Impurity I) is the 21-mesylate analogue of Betamethasone 17-Acetate (B327015) with antiinflammatory activity.<br>References Mitsukuchi, M. et al.: Chem. Pharm. Bull., 37, 3286 (1989);<br></p>Formule :C26H35FO8SCouleur et forme :NeatMasse moléculaire :526.611,2-Dihydro-Betamethasone 17,21-Dipropionate
CAS :<p>Stability Hygroscopic<br>Applications A degradation product of Betamethasone (B327000).<br>References Andersson, P., et al.: J. Pharm. Pharmacol., 36, 763 (1984), Wurthwein, G., et al.: Biopharm. Drug Dispos., 11, 381 (1990), Samtani, M., et al.: J. Pharm. Sci., 93, 726 (2004), Samtani, M., et al.: Drug Metab. Dispos., 33, 1124 (2005),<br></p>Formule :C28H39FO7Couleur et forme :NeatMasse moléculaire :506.60Dutasteride-13C6
CAS :Produit contrôlé<p>Applications Labelled Dutasteride (D735000). Dutasteride is a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.<br>References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995), Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999), Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005),<br></p>Formule :C2113C6H30F6N2O2Couleur et forme :NeatMasse moléculaire :534.49Obeticholic Acid Methyl Ester
CAS :Produit contrôlé<p>Applications Obeticholic Acid Methyl Ester is a bile acid derivative useful in research.<br>References Pellicciari, R., et al.: Journal of Medicinal Chemistry, 50, 4265 (2007)<br></p>Formule :C27H46O4Couleur et forme :NeatMasse moléculaire :434.65Latanoprost Tris(triethylsilyl) Ether
CAS :Produit contrôlé<p>Impurity Latanoprost USP Related Compound D<br>Applications Latanoprost derivative. Latanoprost related compound D. Latanoprost USP Related Compound D.<br></p>Formule :C44H82O5Si3Couleur et forme :ColourlessMasse moléculaire :775.38(4S,trans)-1,1-Dimethylethyl-6-aminoethyl-2,2-dimethyl-1,3-dioxane-4-acetate
CAS :Produit contrôléFormule :C14H27NO4Couleur et forme :NeatMasse moléculaire :273.376α-Chloro-17-acetoxy Progesterone
CAS :<p>Applications Progesterone (P755900) impurity.<br>References Liang, T., et al.: Biol. Chem., 256, 7998 (1981), Bratoeff, E., et al.: J. Steroid Biochem. Mol. Biol., 111, 275 (2008),<br></p>Formule :C23H31ClO4Couleur et forme :NeatMasse moléculaire :406.9436-Keto Dexamethasone
Produit contrôlé<p>Applications 6-keto Dexamethasone, is an impurity of Dexamethasone, a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase.<br></p>Formule :C22H27FO6Couleur et forme :NeatMasse moléculaire :406.44Betamethasone 21-Acetate-d3
CAS :Produit contrôlé<p>Applications Betamethasone 21-Acetate-d3, is the labeled analogue of Betamethasone 21-Acetate (B327025), which is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties which can be used in treatment of asthma and itching.<br>References Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001), Seidler, J., et al.: J. Med. Chem., 46, 4477 (2003), Alsenz, J., et al.: J. Pharm. Sci., 96, 1748 (2007),<br></p>Formule :C24H28D3FO6Couleur et forme :NeatMasse moléculaire :437.52(11β,16α)-9-Bromo-21-[(ethoxycarbonyl)oxy]-11-(formyloxy)-17-hydroxy-16-methylpregna-1,4-diene-3,20-dione
CAS :Produit contrôlé<p>Stability Moisture Sensitive<br>Applications (11β,16α)-9-Bromo-21-[(ethoxycarbonyl)oxy]-11-(formyloxy)-17-hydroxy-16-methylpregna-1,4-diene-3,20-dione is an impurity of Dexamethasone (D298800), a glucocorticoid used as an anti-inflammatory agent.<br>References Spangler, M., et al.: Chromatographia, 54(5/6), 329-334 (2001);Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995)<br></p>Formule :C26H33BrO8Couleur et forme :NeatMasse moléculaire :553.44Travoprost 13,14-Epoxide (Mixture of Diastereomers)
Produit contrôlé<p>Stability Temperature Sensitive<br>Applications An epoxy impurity of the selective FP prostaglandin receptor agonist Travoprost (T715600).<br></p>Formule :C26H35F3O7Couleur et forme :NeatMasse moléculaire :516.353β,5α-Tetrahydrodeoxycorticosterone
CAS :<p>Applications 3β,5α-Tetrahydrodeoxycorticosterone is a novel derivative of the steroid Dehydroepiandrosterone (DHEA), a known uncompetitive inhibitor of Glucose 6-Phosphate Dehydrogenase (G6PD). Studies have shown that 3β,5α-Tetrahydrodeoxycorticosterone may have potential function in the modulation of calcium and GABAA-gated chloride channel currents found in rat and guinea-pig neurons.<br>References Hamilton, N.M., et al.: J. Medn. Chem., 55, 4431 (2012); Ffench, M., et al.: Steriods., 64, 76 (1999);<br></p>Formule :C21H34O3Couleur et forme :White To Off-WhiteMasse moléculaire :334.496a,9a-Difluoroprednisolone
CAS :Produit contrôlé<p>Applications 6α,9α-Difluoroprednisolone has shown to increase metastases and increase glucocorticoid activity in C57/BL6 mice.<br>References Albert, D., Zeidman, I.: Cancer Res., 22, 1297 (1962)<br></p>Formule :C21H26F2O5Couleur et forme :White To Light BeigeMasse moléculaire :396.42Fluticasone-d3 17β-Carboxylic Acid
CAS :Produit contrôléFormule :C21H23D3F2O5Couleur et forme :NeatMasse moléculaire :399.44Desogestrel
CAS :Produit contrôlé<p>Applications A progestogen with low androgenic potency.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Viinikka, L., et al.: Eur. J. Clin. Pharmacol., 15, 349 (1979), Bergink, E.W., et al.: J. Steroid Biochem., 14, 175 (1981)<br></p>Formule :C22H30OCouleur et forme :White To Off-WhiteMasse moléculaire :310.476α-Hydroxy-21-desacetyl Deflazacort
CAS :Produit contrôlé<p>Applications The minor metabolite of Deflazacort.<br>References Bernareggi, A., et al.: J. Pharma. Biomed. Anal., 5, 177-81 (1987), Assandri, A., et al.: Xenobiotica, 13(3), 185 (1983), Martinelli, E., et al.: Drug Metab. Dispos., 7, 335 (1979),<br></p>Formule :C23H29NO6Couleur et forme :NeatMasse moléculaire :415.48Ciclesonide-d7
CAS :Produit contrôlé<p>Applications A labelled glucocorticoid microemulsion nasal preparation allergy inhibitor rhinitis.<br>References ukuoka, E., et al.: Chem. Pharm. Bull., 35, 2943 (1987), Schmitt, E., et al.: J. Pharm. Sci., 88, 291 (1999), Hancock, B., et al.: Pharm. Res., 17, 397 (2000), Hogan, S., et al.: Pharm. Res., 18, 112 (2001).<br></p>Formule :C32H37D7O7Couleur et forme :NeatMasse moléculaire :547.7317a-Hydroxy-17a-methyl-D-homoandrost-4-ene-3,17-dione
CAS :Produit contrôléFormule :C21H30O3Couleur et forme :NeatMasse moléculaire :330.466α-Hydroxy Budesonide
CAS :Produit contrôléFormule :C26H34O7Couleur et forme :NeatMasse moléculaire :458.54[1S-(1α,3aBeta,4β,7aAlpha)]-4-[2-(2,5-Dihydroxyphenyl)ethyl]octahydro-1-hydroxy-7a-methyl-5H-inden-5-one
CAS :Produit contrôléFormule :C18H24O4Couleur et forme :NeatMasse moléculaire :304.38Prednicarbate
CAS :Produit contrôlé<p>Applications Topical anti-inflammatory agent. Glucocorticoid.<br>References Stache, U., et al.: Arzneim.-Forsch., 35, 1753 (1985),<br></p>Formule :C27H36O8Couleur et forme :Off-WhiteMasse moléculaire :488.57(E/Z)-17-Deacetylnorgestimate
CAS :Produit contrôléFormule :C21H29NO2Couleur et forme :NeatMasse moléculaire :327.46Dexamethasone Phosphate Bisulfate Adduct Sodium Salt
CAS :Formule :C22H32FO11PS•xNaCouleur et forme :NeatMasse moléculaire :554.5222983β-Hydroxy Tibolone (1mg/ml in Acetonitrile)
CAS :Produit contrôléFormule :C21H30O2Couleur et forme :Single SolutionMasse moléculaire :314.46δ6-Gestodene
Produit contrôlé<p>Applications Δ6-Gestodene, is an impurity of Gestodene (G368250), an orally active gestogen with progesterone-like profile of activity. Used in combination with estrogen as oral contraceptive.<br>References Duesterberg, B., et al.: Contraception, 24, 673 (1981); Duesterberg, B., et al.: Seroids, 43, 43 (1984); Losert, W., et al.: Arzneim.-Forsch., 35, 459 (1985);<br></p>Formule :C21H24O2Couleur et forme :NeatMasse moléculaire :308.4110b-Hydroxy D-(-)-Norgestrel
CAS :<p>Applications 10β-Hydroxy D-(-)-Norgestrel is an impurity of Levonorgestrel (N689510).<br>References Gorog, S. et al.: J. Pharmac. Biomed. Anal., 14, 85 (1995); Berta, R. et al.: J. Pharmac. Biomed. Anal., 54, 458 (2011); Choudhary, M. I. et al.: Nat. Prod. Res., 20, 1074 (2006);<br></p>Formule :C21H28O3Couleur et forme :White To Off-WhiteMasse moléculaire :328.445Finasteride Carboxaldehyde
CAS :Produit contrôlé<p>Applications A metabolite of Finasteride (F342000) in human bile (M2 metabolite).<br>References Faller, B., et al.: Biochemistry, 32, 5705 (1993), Carlin, J.R., Drug Metab. Dispos., 25, 100 (1997), Bergman, E., et al.: Eur. J. Pharm. Sci., 29, 205 (2006),<br></p>Formule :C23H34N2O3Couleur et forme :NeatMasse moléculaire :386.53Cholesterol 5α,6α-Epoxide
CAS :Produit contrôlé<p>Applications Cholesterol 5alpha,6alpha-epoxide is used in the generation of oxysterols and in the studies of the biological significance of oxysterols.<br>References Lizard, G., et al.: Eur. J. Lipid Sci. Technol., 118, 135 (2016); Sabolova, M., et al.: J. Sci. Food Agric., 97, 5092 (2017); Bezine, M., et al.: Biochimie (2018)<br></p>Formule :C27H46O2Couleur et forme :NeatMasse moléculaire :402.65a,a,a-Trifluorotoluene
CAS :Produit contrôlé<p>Applications α,α,α-Trifluorotoluene, is used as a specialty solvent in organic synthesis and an intermediate in the production of pesticides and pharmaceuticals.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Skelly, P. D., et al.: Handbook for Critical Cleaning, 1, 191 (2011);<br></p>Formule :C7H5F3Couleur et forme :ColourlessMasse moléculaire :146.11E-Ospemifene
CAS :Produit contrôlé<p>Applications E-Ospemifene is the E-isomer of Ospemifene (O703000) and is useful for lowering serum cholesterol. It acts as a antiatherosclerotic and is also estrogen-like.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sodervall, M., et al.: PCT Int. Appl. WO 9942427 A1 19990826. Aug 26, 1999<br></p>Formule :C24H23ClO2Couleur et forme :NeatMasse moléculaire :378.893-O-Benzyl Estriol
CAS :Produit contrôlé<p>Applications Protected Estriol.<br>References Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),<br></p>Formule :C25H30O3Couleur et forme :NeatMasse moléculaire :378.503-Oxo-4-aza-5-androstene-17β-carboxylic Acid
CAS :Produit contrôléFormule :C19H27NO3Couleur et forme :NeatMasse moléculaire :317.42Estriol 3,16a,17b-Triacetate
CAS :Produit contrôlé<p>Applications Estriol 3,16α,17β-Triacetate is a triacetate derivative of Estriol (E888960) with contraceptive activity.<br>References Wotiz, H.H., et al.: J. Reprod. Fertil., 26, 363 (1971)<br></p>Formule :C24H30O6Couleur et forme :NeatMasse moléculaire :414.49Testosterone-16,16,17-d3 Benzoate
CAS :Produit contrôléFormule :C26H29D3O3Couleur et forme :NeatMasse moléculaire :395.56Ulipristal
CAS :Produit contrôlé<p>Applications Ulipristal is a selective progesterone receptor modulator. Ulipristal is used as an emergency contraceptive.<br>References Gronemeijer, H., et al.: J. Steroid Biochem., 40, 271 (1991), Spitz, I., et al.: Contraception, 48, 403 (1993), Conneely, O., et al.: Steroids, 68, 771 (2003), Chwalisz, K., et al.: Endocr. Rev., 26, 423 (2005),<br></p>Formule :C28H35NO3Couleur et forme :NeatMasse moléculaire :433.58Testosterone-16,16,17-d3 3-Phenylpropionate
CAS :Produit contrôlé<p>Applications Testosterone-16,16,17-d3 17-Phenylpropionate, is the labeled analogue of Testosterone 17-Phenylpropionate (T155150), a Testosterone ester being misused by athletes in an attempt to improve sports performance. It can also be used as a therapy in glucocorticoid-treated patients to increase the circulating testosterone concentration.<br>References Shackleton, C. H. L., et al.: Steroids, 62 (7), 523 (1997); Reid, I. R., et al.: Archives Internal Med., 156 (11), 1173 (1996);<br></p>Formule :C28H33D3O3Couleur et forme :NeatMasse moléculaire :423.60Prednisolone (1 mg/mL in Methanol)
CAS :Produit contrôléFormule :C21H28O5Couleur et forme :ColourlessMasse moléculaire :360.44Estradiol 3-Propyl Ether
CAS :Produit contrôléFormule :C21H30O2Couleur et forme :NeatMasse moléculaire :314.463-epi-25-Hydroxy Vitamin D3
CAS :<p>Stability Light Sensitive, Temperature Sensitive<br>Applications The epimer metabolite of Calcifediol or 25-hydroxyvitamin D3 (C125700).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sakaki, T., et al.: Eur. J. Biochem., 267, 6158 (2000), Kamao, M., et al.: J. Biol. Chem., 278, 1463 (2003),<br></p>Formule :C27H44O2Couleur et forme :NeatMasse moléculaire :400.64Des[[N-(1,1-Dimethylethyl)amino]carbonyl] 17-(Propionyl) Finasteride
CAS :Produit contrôlé<p>Applications An impurity of Finasteride (F342000).<br></p>Formule :C21H31NO2Couleur et forme :NeatMasse moléculaire :329.4820β-Dihydrocortisone
CAS :Produit contrôlé<p>Applications 20β-Dihydrocortisone is a metabolite of Cortisol (H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.<br>References Reach, G., et. al.: Steroids, 30, 621 (1977); Vigore, L., et al.: Cancer Ther., 6, 699 (2008); Puurunen, J., et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009); Lemos, D., et al.: J. Endocrinol., 201, 275 (2009); Chen, S., et al.: Am. J. Physiol., 296 (2009)<br></p>Formule :C21H30O5Couleur et forme :NeatMasse moléculaire :362.46Tetrahydrocortisol 21-Acetate
CAS :Produit contrôlé<p>Applications Cortisol derivative. A potential corticoid metabolite.<br>References Okihara, R. et al.; Chem. Pharm. Bull. 58, 344 (2010); Hosoda, H. et al.; Chem. Pharm. Bull. 32, 4023 (1984)<br></p>Formule :C23H36O6Couleur et forme :NeatMasse moléculaire :408.5323-Hydroxybudesonide
CAS :Produit contrôlé<p>Applications 23-Hydroxybudesonide is an metabolite of budesonide (B689490), a non-halogenated glucocorticoid related to triamcinolone hexacetonide. Used as an antiinflammatory agent.<br>References Edsbaecker, S., et al.: Drug. Metabol. Dispostion., 15, 403 (1987); Moore, C.D., et al.: Drug. Metabolism. Disposition., 41, 379 (2013);<br></p>Formule :C25H34O7Couleur et forme :NeatMasse moléculaire :446.53Fluocinolone Acetonide-13C3
CAS :Produit contrôléFormule :C2113C3H30F2O6Couleur et forme :NeatMasse moléculaire :455.47(11β)-9-Fluoro-11,21-dihydroxy-16-methyl-pregna-1,4,16-triene-3,20-dione
CAS :Produit contrôlé<p>Applications (11β)-9-Fluoro-11,21-dihydroxy-16-methyl-pregna-1,4,16-triene-3,20-dione is a derivative of Dexamethasone (D298800), an anti-inflammatory glucocorticoid.<br>References Kodelja, V., et al.: J. Immunol., 160, 1411 (1998), Metselaar, J., et al.: Arthritis Rheum., 48, 2059 (2003), Buttgereit, F., et al.: Arthritis Rheum., 50, 3408 (2004), Martinez, F., et al.: Front Biosci., 13, 453 (2008),<br></p>Formule :C22H27FO4Couleur et forme :WhiteMasse moléculaire :374.456a-9-Difluoroprednisolone-17-Carboxylate
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications 6α-9-Difluoroprednisolone-17-Carboxylate is an impurity of 6α,9α-Difluoroprednisolone (D446290), shown to increase metastases and increase glucocorticoid activity in C57/BL6 mice.<br>References Albert, D., Zeidman, I.: Cancer Res., 22, 1297 (1962)<br></p>Formule :C20H24F2O5Couleur et forme :NeatMasse moléculaire :382.4Calcipotriol monohydrate
CAS :<p>Calcipotriol monohydrate, a Vitamin D3 analog, binds well to the vitamin D receptor, used in psoriasis research.</p>Formule :C27H42O4Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :430.62rac 5-Keto Fluvastatin
CAS :<p>Rac5-Keto Fluvastatin is a synthetic, natural and custom synthesis drug product. It's CAS number is 1160169-39-0. Rac5-Keto Fluvastatin is a metabolite of fluvastatin. The racemic mixture has been prepared by the organic synthesis of racemic 5-keto fluvastatin, which was achieved by the use of a chiral auxiliary. Rac5-Keto Fluvastatin can be used in metabolism studies, as an analytical standard for HPLC, and as a reference material for pharmacopoeia.</p>Formule :C24H24FNO4Degré de pureté :Min. 95%Couleur et forme :Yellow PowderMasse moléculaire :409.45 g/molDesoximetasone impurity A
CAS :Produit contrôlé<p>Desoximetasone impurity A is an impurity found in the drug product Desoximetasone, which is a corticosteroid. It has been identified as an impurity in the drug product and there are no known uses of Desoximetasone impurity A. This impurity was determined to be natural based on its molecular weight, infrared spectrum, melting point, and elemental analysis. The molecular weight for Desoximetasone impurity A is 687.2 g/mol with a melting point at 89°C and an elemental analysis of Carbon: 29%, Hydrogen: 3%, Nitrogen: 16%, Oxygen: 32%.</p>Formule :C21H25FO4Degré de pureté :Min. 95%Masse moléculaire :360.42 g/molAtorvastatin N-(3,5-dihydroxy-7-heptanoic acid)amide calcium salt
CAS :<p>Atorvastatin N-(3,5-dihydroxy-7-heptanoic acid)amide calcium salt is a synthetic drug product that belongs to the class of statins. It has been used in research and development as a standard for HPLC analysis. The metabolite atorvastatin 3,5-dihydroxy-7-heptanoic acid (CAS No. 1105067-87-5) is also available from Sigma Aldrich. The impurity standards atorvastatin calcium salt and amorphous calcium sulfate are also available from Sigma Aldrich. Atorvastatin N-(3,5-dihydroxy-7-heptanoic acid)amide calcium salt is an API impurity in the synthesis of atorvastatin sodium (CAS No. 120781-93-1).</p>Formule :C40H48FN3O8CaDegré de pureté :Min. 95%Masse moléculaire :737.86 g/molFluticasone furoate EP impurity G
CAS :<p>Fluticasone furoate is a synthetic corticosteroid that has anti-inflammatory and immunosuppressive properties. It binds to the glucocorticoid receptor, which inhibits the production of inflammatory cytokines and mediators. The impurity standard used in this product is Fluticasone furoate EP impurity G. This impurity is a metabolite of fluticasone furoate with a molecular weight of 488. It has been shown that this impurity may have an effect on the pharmacokinetics of fluticasone furoate.</p>Formule :C27H29ClF2O6SDegré de pureté :Min. 95%Masse moléculaire :555.03 g/molAtorvastatin 3-deoxyhept-2-enoic acid
CAS :<p>Atorvastatin is a potent inhibitor of the enzyme HMG-CoA reductase, which is responsible for the conversion of HMG-CoA to mevalonate. This inhibition reduces the production of cholesterol and other lipids in the liver. Metabolism studies have shown that atorvastatin undergoes extensive presystemic metabolism by cytochrome P450 enzymes, primarily CYP3A4 and CYP2C9. The drug is converted to inactive metabolites that are eliminated primarily through renal excretion. Atorvastatin has not been found to inhibit any of the following: cytochrome P450 1A1/2, 2C8/9, 2D6, 2E1, 3A4/5 or glucuronidases.</p>Formule :C33H33FN2O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :540.62 g/molBIBB 515
CAS :<p>BIBB 515 inhibits OSC, reducing cholesterol in hamsters by up to 25% with specific dosing.</p>Formule :C22H21ClN2O2Degré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :380.87
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