Phosphates et Phosphonates Organiques
Les phosphates organiques sont des composés contenant un groupe phosphate (-PO₄) lié à un atome de carbone dans une structure organique, généralement en combinaison avec des alcools, des acides ou des amines. Ces composés sont utilisés dans la formulation des API pour améliorer la solubilité, la stabilité et la biodisponibilité des principes actifs. Les phosphates organiques jouent également un rôle dans la libération contrôlée des médicaments et dans l'amélioration de l'absorption de certains traitements.
Les phosphonates organiques contiennent un groupe phosphonate (-PO₃H₂) dans lequel l'atome de phosphore est lié à un atome de carbone et à deux groupes oxygène. Ces composés ont des propriétés pharmacologiques importantes, notamment dans l'inhibition des enzymes et la modulation des processus biochimiques. Les phosphonates organiques sont utilisés dans la production d'API ciblant le métabolisme osseux, les infections bactériennes ou les traitements antiviraux grâce à leurs effets biologiques spécifiques.
Chez CymitQuimica, nous proposons des phosphates et des phosphonates organiques pour la recherche en chimie médicinale, biochimie et développement de formulations avancées.
1201 produits trouvés pour "Phosphates et Phosphonates Organiques"
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Diatrizoic Acid Dihydrate
CAS :<p>Diatrizoic Acid Dihydrate is used as a radiocontrast compound. It is used for imaging the gastrointestinal tract in patients allergic to barium.</p>Formule :C11H13I3N2O6Couleur et forme :SolidMasse moléculaire :649.943α-Hydroxy Pravastatin Lactone-d3
CAS :Produit contrôlé<p>Applications A labelled metabolite of Pravastatin (P702000), a competitive inhibitor of HMG-CoA reductase.<br>References Serizawa, N., et al.: J. Antibiot., 36, 604 (1983), White, H.D, et al.: N. Engl. J. Med., 343, 317 (2000)<br></p>Formule :C23H31D3O6Couleur et forme :NeatMasse moléculaire :409.53Zofenoprilat Sodium Salt (90%)
CAS :<p>Stability Very Hygroscopic<br>Applications The active metabolite of Zofenopril, an ACE inhibitor.<br>References Cushman, D., et al.: Br. J. Clin. Pharmacol., 28, 115S (1989), Kelly, J., et al.: Clin. Pharmacokinet., 19, 177 (1990), Liu, X., et al.: Cardiv. Drugs Ther., 6, 437 (1992), Marzo, A., et al.: Arzneim.- Forsch., 49, 992 (1999), Subissi, A., et al.: Cardiv. Drug Rev., 17, 2 (1999),<br></p>Formule :C15H18NNaO3S2Degré de pureté :90%Couleur et forme :White SolidMasse moléculaire :347.433-Bromo-2-methylpropionic Acid
CAS :<p>Impurity Captopril EP Impurity D<br>Stability Hygroscopic<br>Applications 3-Bromo-2-methylpropionic Acid (Captopril EP Impurity D) is used in the preparation of captopril selenium analogs as antioxidants and ACE inhibitors used as antihypertensive drugs.<br>References Bhuyan, B. et al.: Org. Biomol. Chem., 9, 1356 (2011);<br></p>Formule :C4H7BrO2Couleur et forme :Colourless LiquidMasse moléculaire :167.003,3'-Disulfanediylbis[(2S)-2-methylpropanoic] Acid
CAS :Produit contrôléFormule :C8H14O4S2Couleur et forme :NeatMasse moléculaire :238.32Deferasirox-d4
CAS :Produit contrôlé<p>Applications Labelled orally active tridentate iron chelator.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hershko, C., et al.: Blood, 97, 1115 (2001), Galanello, R., et al.: J. Clin. Pharmacol., 43, 565 (2003), Nick, H., et al.: Curr. Med. Chem., 10, 1065 (2003),<br></p>Formule :C212H4H11N3O4Couleur et forme :NeatMasse moléculaire :377.39Minodronic Acid
CAS :Produit contrôlé<p>Applications Minodronic acid is developed for osteoporosis treatment.<br>References Tanishima, S., et al.: Clin. Interv. Aging, 8, 185 (2013)<br></p>Formule :C9H12N2O7P2Couleur et forme :NeatMasse moléculaire :322.15Malathion (Diethyl-d10)
CAS :Produit contrôlé<p>Applications Malathion (Diethyl-d10) is used as one of the substances for the clean-up step in post-harvest pesticide residue analysis.<br>References Ucles, A., et al.: Talanta, 144, 51 (2015)<br></p>Formule :C102H10H9O6PS2Couleur et forme :Light YellowMasse moléculaire :340.42Hydroxy Cyclophosphamide Semicarbazone-d4 (>80%)
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Isotope labelled Aldophosphamide Semicarbazone is a major metabolite of cyclophosphamide (C988580), a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity.This compound is suitable for aldehyde dehydrogenase (ALDH) related research.<br>References Struck, R.F., et al.: Cancer. Rsch., 34, 2933 (1947); Wheeler, A.G., et al.: Toxicol. Appl. Pharmacol., 4, 324 (1962), Fraiser, L.H., et al.: Drugs, 42, 781 (1991), Colvin, O.M., et al.: Curr. Pharmaceut. Design, 5, 555 (1999),<br></p>Formule :C8H14D4Cl2N5O3PDegré de pureté :>80%Couleur et forme :NeatMasse moléculaire :338.16Fenthion Sulfone-d6
CAS :Produit contrôlé<p>Applications Labelled Fenthion Sulfone (F278015). Fenthion Sulfone is a metabolite of the organothiophosphate insecticide Fenthion (F278000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Oh, C., et al.: Bull Environ. Contam. Toxicol., 78, 314 (2007); Wang, W., et al.: Anal. Chim. Acta, 602, 211 (2007);<br></p>Formule :C10H9D6O5PS2Couleur et forme :NeatMasse moléculaire :316.36N-Nitroso Cilazapril (Phenyl-D5)
CAS :Produit contrôléFormule :C22D5H25N4O6Couleur et forme :NeatMasse moléculaire :451.528m-Salicylic Acid
CAS :Produit contrôlé<p>Applications m-Salicylic Acid is widely used in organic synthesis. It is also an important active metabolite of aspirin (A187780).<br>References Haynes, M., et al.: CRC H.b Chem. Phys., 92, 306 (2011)<br></p>Formule :C7H6O3Couleur et forme :Off-WhiteMasse moléculaire :138.12Hydroxy Cyclophosphamide Semicarbazone (80%)
CAS :Produit contrôlé<p>Applications Aldophosphamide Semicarbazone is a major metabolite of cyclophosphamide (C988580), a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity.This compound is suitable for aldehyde dehydrogenase (ALDH) related research.<br>References Struck, R.F., et al.: Cancer. Rsch., 34, 2933 (1947); Wheeler, A.G., et al.: Toxicol. Appl. Pharmacol., 4, 324 (1962); Fraiser, L.H., et al.: Drugs, 42, 781 (1991); Colvin, O.M., et al.: Curr. Pharmaceut. Design, 5, 555 (1999);<br></p>Formule :C8H18Cl2N5O3PDegré de pureté :80%Couleur et forme :NeatMasse moléculaire :334.14Diroximel Fumarate
CAS :Produit contrôléFormule :C11H13NO6Couleur et forme :NeatMasse moléculaire :255.22Captopril EP Impurity N
CAS :<p>Captopril EP Impurity N is a synthetic impurity found in Captopril EP, which is used as a drug product for the treatment of hypertension. The impurity standard for Captopril EP Impurity N is available on request.</p>Formule :C8H14O4S2Degré de pureté :Min. 95%Masse moléculaire :238.33 g/molEnalaprilat benzyl ester
CAS :<p>Enalaprilat benzyl ester is a drug product that is custom synthesized according to the customer's specifications. It is a white or off-white crystalline powder and has a purity of 99%. Enalaprilat benzyl ester is used in the development of drugs, research and development, and analytical studies. It can be used as an impurity standard to test for enalaprilat in pharmaceutical products. It can also be used as a metabolite standard to measure blood levels of enalaprilat.</p>Formule :C25H30N2O5Degré de pureté :Min. 95%Masse moléculaire :438.52 g/molCalcipotriol EP Impurity I
<p>Calcipotriol EP Impurity I is a metabolite of calcipotriol which acts as a natural, synthetic and analytical standard for the compound. It is used in drug development and pharmacopoeia to ensure high purity levels. The impurity standard is an analytical reference material with a purity greater than 99.5% and contains no more than 10% of any other impurity.</p>Formule :C27H40O3Degré de pureté :Min. 95%Masse moléculaire :412.6 g/mol(S)-3''-Hydroxy pravastatin sodium salt
CAS :<p>(S)-3''-Hydroxy pravastatin sodium salt is a drug product that is custom synthesized. It is the sodium salt of (S)-3''-hydroxypravastatin, which has been shown to be a natural product with high purity. The metabolite of (S)-3''-hydroxypravastatin sodium salt is 3'-hydroxypravastatin. This product can be used for analytical purposes as well as in pharmacopoeia, drug development, and research and development. It can also be used as an impurity standard for HPLC and GC analysis.</p>Formule :C23H35NaO8Degré de pureté :Min. 95%Masse moléculaire :462.51 g/molPravastatin 6-oxo Impurity
CAS :<p>Pravastatin 6-oxo Impurity is an impurity of Pravastatin, a drug used in the treatment of high cholesterol. The impurity has been identified through analytical methods and is characterized by HPLC analysis. This substance has been shown to be present in at least 0.1% of the drug product and may be present as a result of incomplete synthesis or a side-reaction during synthesis.</p>Formule :C23H34O7Degré de pureté :Min. 95%Masse moléculaire :422.51 g/mol3α-Hydroxy pravastatin sodium salt
CAS :<p>3alpha-Hydroxy pravastatin sodium salt is a white to off-white crystalline powder. It is used as an analytical standard for 3alpha-hydroxypravastatin and its metabolites. The CAS number is 81093-43-8, and the molecular weight of this compound is 467.6 g/mol. This product can be custom synthesized to meet your needs.</p>Formule :C23H35NaO7Degré de pureté :Min. 95%Couleur et forme :Off-White PowderMasse moléculaire :446.51 g/mol
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