Nucléosides et Nucléotides
Les nucléosides sont des composés formés par une base azotée liée à un sucre (ribose ou désoxyribose). Lorsqu’un groupe phosphate est ajouté au nucléoside, un nucléotide est formé. Ces composés sont essentiels en biologie cellulaire, car les nucléotides sont les blocs fondamentaux de l’ADN et de l’ARN, responsables du stockage et de la transmission de l’information génétique. Les nucléosides ont des applications dans le traitement des maladies virales, en tant qu’inhibiteurs de la réplication virale. Les nucléotides, en plus de leur rôle structurel dans les acides nucléiques, interviennent dans les processus énergétiques, comme la synthèse de l’ATP.
Chez CymitQuimica, nous proposons une large gamme de nucléosides et de nucléotides essentiels à la recherche en biologie moléculaire, virologie et pharmacologie.
3413 produits trouvés pour "Nucléosides et Nucléotides"
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Methyl 2-deoxy-D-ribopyranoside
CAS :<p>Methyl 2-deoxy-D-ribopyranoside (2DDR) is a natural compound that can be found as an impurity in some pharmaceuticals. The chemical structure of 2DDR is similar to 6-fluoro-3-indoxyl beta-D-galactopyranoside, which is used to treat tuberculosis. The metabolism of 2DDR has been studied, and it has been found that this metabolite is excreted in the urine unchanged or conjugated with glucuronic acid. This product can be used for drug development and research and development. It can also be used as an impurity standard for HPLC analysis or as a custom synthesis for niche applications.</p>Formule :C6H12O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :148.16 g/molS19-1035
<p>S19-1035: potent AKR1C3 inhibitor with 3.04 nM IC50, useful for tumor research.</p>Formule :C19H17ClN2O3Degré de pureté :99.98%Couleur et forme :SoildMasse moléculaire :356.80Phox-I2
CAS :<p>Phox-I2 is an NOX2-specific inhibitor. Phox-I2 reverts ROS-accumulation and leads to refusion of mitochondrial networks.</p>Formule :C18H15N3O4Degré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :337.33N6-(2-Phenylethyl)adenosine
CAS :<p>N6-(2-Phenylethyl)adenosine (N6-Phenethyladenosine) is an adenosine derivative and an agonist of adenosine receptors with Ki values of 11.8 nM and 30.1 nM for</p>Formule :C18H21N5O4Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :371.39APX-115
CAS :<p>APX-115 (Ewha-18278) (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4).</p>Formule :C17H18ClN3ODegré de pureté :98.62%Couleur et forme :SolidMasse moléculaire :315.8Meropenem EP impurity A
CAS :<p>Meropenem EP impurity A is a heterocyclic nitro compound that is used to treat various infectious diseases. Meropenem EP impurity A is an inhibitor of the toll-like receptor, which is a protein that recognizes and binds to bacterial lipopolysaccharide and mediates inflammation. This drug may be effective in treating colorectal carcinoma, autoimmune diseases, chronic bronchitis, cancer, and other inflammatory diseases. Meropenem EP impurity A also has anti-cancer properties due to its structural similarity with the chemotherapeutic agent 5-fluorouracil. Meropenem EP impurity A inhibits the synthesis of proteins by binding to the aminoacyl-tRNA synthetase enzyme and blocking the production of proteins vital for cell division.</p>Formule :C17H27N3OS6Degré de pureté :95%NmrCouleur et forme :PowderMasse moléculaire :401.5 g/molEmtricitabine impurity 17
CAS :<p>Please enquire for more information about Emtricitabine impurity 17 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C8H10FN3O4SDegré de pureté :Min. 95%Masse moléculaire :263.24 g/molBrivudine monophosphate
CAS :<p>Brivudine monophosphate, a phosphate ester, inhibits DNA repair, induces apoptosis, and may downregulate STAT3 and chemoresistance genes.</p>Formule :C11H14BrN2O8PCouleur et forme :SolidMasse moléculaire :413.12GLX481304
CAS :<p>GLX481304 is a selective Nox-2 and Nox-4 inhibitor, exhibiting IC50 values of 1.25 μM.</p>Formule :C23H29N7OCouleur et forme :SolidMasse moléculaire :419.52AMPA receptor modulator-2
CAS :<p>AMPA receptor modulator-2 is a modulator of AMPA receptor. The pIC50 value for TARPγ2 dependent AMPA receptor is 10.1.</p>Formule :C15H6F6N4OSDegré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :404.29Zidovudine diphosphate
CAS :<p>Zidovudine diphosphate, an NRTI antiretroviral, treats HIV/AIDS by blocking reverse transcriptase, preventing viral DNA synthesis.</p>Formule :C10H15N5O10P2Couleur et forme :SolidMasse moléculaire :427.2NOX2-IN-2
CAS :<p>NOX2-IN-2 (compound 33) is a potent inhibitor of NOX2, disrupting the p47phox-p22phox protein-protein interaction with a dissociation constant (K i) of 0.24 μM.</p>Formule :C25H25N7O3Couleur et forme :SolidMasse moléculaire :471.51Emtricitabine triphosphate tetrasodium salt
CAS :<p>Emtricitabine triphosphate tetrasodium salt is the tetrasodium salt form of the phosphorylated anabolite (-)-Emtricitabine triphosphate, an active nucleoside</p>Formule :C8H9FN3Na4O12P3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :575.11ES 936
CAS :<p>ES 936 is a potent and selective NQO1 inhibitor, inhibiting more than 95% of NQO1 100 nM, with a cell line-dependent inhibition duration.</p>Formule :C18H16N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :356.33ML-090
CAS :<p>ML-090 is NOX1-specific inhibitor(IC50 = 90 nM) which is >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50s >10 μM).</p>Formule :C14H10N4Degré de pureté :98.55%Couleur et forme :SolidMasse moléculaire :234.26Carbovir
CAS :<p>Carbovir, an NRTI, induces mitochondrial toxicity in human liver cancer cells.</p>Formule :C11H13N5O2Couleur et forme :SolidMasse moléculaire :247.25Galidesivir dihydrochloride
CAS :<p>Galidesivir inhibits RdRP; has broad antiviral effects on various RNA viruses; effective against Ebola, Marburg in animals.</p>Formule :C11H17Cl2N5O3Couleur et forme :SolidMasse moléculaire :338.19Ganciclovir triphosphate
CAS :<p>Ganciclovir triphosphate: synthetic 2'-deoxy-guanosine analog, treats/prevents CMV, IC50 of 0.01 μM, effective across species.</p>Formule :C9H16N5O13P3Couleur et forme :SolidMasse moléculaire :495.17Sorivudine
CAS :<p>Sorivudine (BV-araU) is an antiviral blocking DNA synthesis in viruses like varicella, HSV-1, and Epstein-Barr.</p>Formule :C11H13BrN2O6Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :349.13GS 441524 triphosphate
CAS :<p>Triphosphorylated form of an antiviral nucleoside analog with activity against zoonotic feline infectious peritonitis virus (FIPV) and severe acute respiratory syndrome (SARS) virus from Coronaviridae family. The compound is the biologically active form of the GS 441524 prodrug and being triphosphorylated, it competes with natural nucleoside triphosphates in cells and interferes with viral RNA synthesis. Made to order.</p>Formule :C12H12N5O13P3·4NaDegré de pureté :(31P-Nmr) Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :531.20 g/molLobucavir
CAS :<p>Lobucavir (BMS-180194; SQ 34514) is a nucleoside analogue and an antiviral agent with broad-spectrum activity against various viruses, including HBV, HIV/AIDS, and α, β, and γ herpesviruses (including CMV, herpes simplex virus, varicella-zoster virus, and Epstein-Barr virus).</p>Formule :C11H15N5O3Couleur et forme :SolidMasse moléculaire :265.27Emtricitabine triphosphate
CAS :<p>Emtricitabine triphosphate is an active metabolite of Emtricitabine, a drug for HIV/HBV that inhibits reverse transcriptase.</p>Formule :C8H13FN3O12P3SCouleur et forme :SolidMasse moléculaire :487.19Galidesivir
CAS :<p>Galidesivir (BCX4430) is an antiviral compound that inhibits viral RNA-dependent RNA polymerase (RdRp) activity and reduces lung infections in infected animals.</p>Formule :C11H15N5O3Degré de pureté :96.73% - 99.13%Couleur et forme :SolidMasse moléculaire :265.27
