Nucléosides et Nucléotides
Les nucléosides sont des composés formés par une base azotée liée à un sucre (ribose ou désoxyribose). Lorsqu’un groupe phosphate est ajouté au nucléoside, un nucléotide est formé. Ces composés sont essentiels en biologie cellulaire, car les nucléotides sont les blocs fondamentaux de l’ADN et de l’ARN, responsables du stockage et de la transmission de l’information génétique. Les nucléosides ont des applications dans le traitement des maladies virales, en tant qu’inhibiteurs de la réplication virale. Les nucléotides, en plus de leur rôle structurel dans les acides nucléiques, interviennent dans les processus énergétiques, comme la synthèse de l’ATP.
Chez CymitQuimica, nous proposons une large gamme de nucléosides et de nucléotides essentiels à la recherche en biologie moléculaire, virologie et pharmacologie.
3427 produits trouvés pour "Nucléosides et Nucléotides"
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Dideoxy Adenosine
CAS :Produit contrôléFormule :C10H13N5O2Couleur et forme :NeatMasse moléculaire :235.2432,3-Dichloropropionyl Chloride
CAS :Produit contrôlé<p>Stability Moisture Sensitive<br>Applications 2,3-Dichloropropionyl Chloride is used as a reagent in the synthesis of 6-chloro-5-cyclohexyl-1-indancarboxylic acid, a potent analgesic, antipyretic, and antiinflammatory agent, and its related compounds.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sawa, Y., et al.: Yakugaku Zasshi, 96, 653 (1976)<br></p>Formule :C3H3Cl3OCouleur et forme :NeatMasse moléculaire :161.41(1R,2S,5R)-Menthol-5R-hydroxy-[1,3]-oxathiolane-2R-carboxylate
CAS :Produit contrôléFormule :C14H24O4SCouleur et forme :NeatMasse moléculaire :288.40Emtricitabine Carboxylic Acid
CAS :Produit contrôlé<p>Impurity Emtricitabine Carboxylic Acid Impurity<br>Applications Emtricitabine Carboxylic Acid is an impurity of the antiviral agent Emtricitabine (E525035).<br>References Pendela, M. et al.: Talanta, 82, 125 (2010);<br></p>Formule :C8H8FN3O4SCouleur et forme :NeatMasse moléculaire :261.232-Hydroxyethyl Benzoate(Ethylene Glycol Monobenzoate)
CAS :Produit contrôlé<p>Applications Ethylene Glycol Monobenzoate, is a reagent that can be used as an intermediate in a variety of chemical and biochemical reactions. It is used as an intermediate in the preparation of 1,2-Ethanediol Disodium Salt (E890125), which is the result of the nucleophilic attack on its carbonyl group.<br>References Khouri, F. et al.: J. Am. Chem. Soc., 108, 6683 (1986);<br></p>Formule :C9H10O3Couleur et forme :NeatMasse moléculaire :166.17Bis Valacyclovir (~90%)
CAS :Produit contrôlé<p>Impurity Valaciclovir EP Impurity P<br>Stability Light Sensitive, Temperature Sensitive<br>Applications Bis Valacyclovir (~90%) (Valaciclovir EP Impurity P) is an impurity is listed in Ph. Eur. monograph for Valaciclovir HCl as impurity P and Bis-valaciclovir in USP monograph (impurity K).<br></p>Formule :C27H40N12O8Degré de pureté :~90%Couleur et forme :Off White SolidMasse moléculaire :660.682’-Monodehydroxy-2’-chloro Ganciclovir
CAS :Produit contrôlé<p>Impurity Ganciclovir EP Impurity C<br>Applications 2’-Monodehydroxy-2’-chloro Ganciclovir is an Impurity of Ganciclovir (G235000). 2’-Monodehydroxy-2’-chloro Ganciclovir is a sugar modified acyclic analogue of guanosine (G837900). Studies have shown 2’-Monodehydroxy-2’-chloro Ganciclovir has potential to exhibit virucidal activity. Iso mono chloro ganciclovir<br>References Martin, J.C., et al.: J. Med. Chem., 29, 1384 (1986);<br></p>Formule :C9H12ClN5O3Couleur et forme :White SolidMasse moléculaire :273.682-Deoxy-3,5-di-O-p-toluoyl-a-L-ribofuranosyl Chloride
CAS :<p>Stability Moisture Sensitive, Unstable in Solution<br>Applications 2-Deoxy-3,5-di-O-p-toluoyl-α-L-ribofuranosyl Chloride (cas# 141846-57-3) is a compound useful in organic synthesis.<br></p>Formule :C21H21ClO5Couleur et forme :NeatMasse moléculaire :388.84rac 4-Hydroxy-2-pyrrolidinone
CAS :<p>Applications An intermediate in the preparation of Oxiracetam (O846905).<br>References Kondepudi, D., et al.: Science, 250 975 (1990), Di Silvestro, G., et al.: J. Pharm. Sci., 82, 758 (1993),<br></p>Formule :C4H7NO2Couleur et forme :NeatMasse moléculaire :101.10Peramivir
CAS :<p>Applications A new antiviral agent for influenza treatment; it can be used as neuraminidase inhibitor for treating human and avian influenza.<br>References Whitley, R., et al.: Pediatr. Infect. Dis. J., 20, 127 (2001), Bright, R., et al.: Lancet., 366, 1175 (2005), Deyde, V., et al.: J. Infect. Dis., 196, 249 (2007), Lee, N., et al.: Clin. Infect. Dis., 46, 1323 (2008),<br></p>Formule :C15H28N4O4Couleur et forme :NeatMasse moléculaire :328.413,4-Dihydro-3-oxo-2-pyrazinecarboxamide
CAS :Produit contrôléFormule :C5H5N3O2Couleur et forme :NeatMasse moléculaire :139.11ent-Emtricitabine
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications A reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine (L172500).<br>References Mellors, J., et al.: Science, 72, 1167 (1996), Reimann, K., et al.: J. Virol., 79, 8878 (2005), Rose, J., et al.: J. Biol. Chem., 280, 7413 (2005), Acierno, P., et al.: J. Immunol., 176, 5338 (2006),<br></p>Formule :C8H10FN3O3SCouleur et forme :NeatMasse moléculaire :247.25L-Tetrahydrofolic Acid-d4 (Major) (>70% when packaged)
CAS :Produit contrôlé<p>Applications L-Tetrahydrofolic Acid-d4 (Major) is a folic acid derivative and coenzyme involved in the metabolism of amino and nucleic acids.<br>References Prinz-Langenohl, R., et al.: Brit. J. Pharmacol., 158, 2014 (2009), Martin, H., et al.: Anal. Biochem., 402, 137 (2010), Dasarathy, J., et al.: Am. J. Clin. Nut., 91, 357 (2010), Karas-Kuzelicki, N., et al.: Clin. Biochem., 43, 37 (2010),<br></p>Formule :C19H19D4N7O6Couleur et forme :Light BrownMasse moléculaire :449.455'-Deoxy-5'-chloroadenosine
CAS :<p>Applications 5'-Deoxy-5'-chloroadenosine is an intermediate in the synthesis of 5'-Deoxy-5'-(methylthio)adenosine (D242600), a substrate to study the specificity and kinetics of 5′-methylthioadenosinephosphorylase (MTAP) (EC2.4.2.28), a tumor suppressor gene expressed enzyme that supports the S-adenosylmethionine (AdoMet) and methionine salvage pathways.<br>References Olopade, O., et al.: Cancer Res., 53, 2410 (1993), Hartmann, S., et al.: Clin. Chem., 52, 1127 (2006), Penner, N., et al.: J. Pharm. Biomed. Anal., 52, 534 (2010),<br></p>Formule :C10H12ClN5O3Couleur et forme :NeatMasse moléculaire :285.687Remdesivir impurity 11
CAS :<p>CAS No. 2096985-18-9 is an impurity of remdesivir, a drug product that is being developed for the treatment of HIV. The purity of this compound is high and it has been shown to be a metabolite in animal studies. Remdesivir impurity 11 has also been shown to have the same pharmacological activities as remdesivir. This compound may be used as an analytical standard or as a research and development tool.</p>Formule :C21H23N6O8PDegré de pureté :Min. 95%Masse moléculaire :518.42 g/molAciclovir EP impurity J
CAS :<p>Aciclovir EP impurity J is a drug product that is used as an analytical standard in HPLC. Aciclovir EP impurity J is the natural metabolite of aciclovir, which is an antiviral drug. It is not active against herpesviruses but has been shown to inhibit the growth of human cells infected with cytomegalovirus. Aciclovir EP impurity J has been studied for its effects on drug metabolism and pharmacokinetics. Aciclovir EP impurity J has been shown to be excreted primarily in urine, with some excretion in the feces.</p>Formule :C14H16N10O4Degré de pureté :Min. 95%Masse moléculaire :388.34 g/molMethyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-a-D-glucopyranoside
CAS :<p>Methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-alpha-D-glucopyranoside is an impurity of Dapagliflozin.</p>Formule :C22H27ClO7Degré de pureté :Min. 95%Masse moléculaire :438.9 g/mol1-C-4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]- D-glucitol
CAS :<p>This compound is a research and development impurity standard with a custom synthesis. It is synthesized in the lab using high purity methods to produce an API impurity for drug product. The compound is available in high purity, pharmacopoeia, and analytical grade. This compound is used as an analytical reference standard. Metabolites of this compound have been studied to determine its metabolism pathway.</p>Formule :C21H27ClO7Degré de pureté :Min. 95%Masse moléculaire :426.89 g/mol2'-Epi-lamivudine
CAS :<p>2'-Epi-lamivudine is a chiral, racemic mixture of the two enantiomers of lamivudine. The synthesis and purification of 2'-epi-lamivudine is achieved by using a chiralpak column to separate the optical isomers from each other and then an immunoaffinity column to remove the undesired enantiomer (the S-enantiomer). The final product is a mixture of both enantiomers in a 1:1 ratio, which has been shown to have antiviral activity against HIV.<br>2'-Epi-lamivudine has been shown to be more potent than its parent compound lamivudine and is less toxic. This antiviral agent inhibits HIV replication by inhibiting reverse transcriptase, which is an enzyme that synthesizes viral DNA from viral RNA. It also has anti-inflammatory properties that may be due to inhibition of prostaglandin synthesis.</p>Formule :C8H11N3O3SDegré de pureté :Min. 95%Masse moléculaire :229.26 g/mol
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