Nucléosides et Nucléotides
Les nucléosides sont des composés formés par une base azotée liée à un sucre (ribose ou désoxyribose). Lorsqu’un groupe phosphate est ajouté au nucléoside, un nucléotide est formé. Ces composés sont essentiels en biologie cellulaire, car les nucléotides sont les blocs fondamentaux de l’ADN et de l’ARN, responsables du stockage et de la transmission de l’information génétique. Les nucléosides ont des applications dans le traitement des maladies virales, en tant qu’inhibiteurs de la réplication virale. Les nucléotides, en plus de leur rôle structurel dans les acides nucléiques, interviennent dans les processus énergétiques, comme la synthèse de l’ATP.
Chez CymitQuimica, nous proposons une large gamme de nucléosides et de nucléotides essentiels à la recherche en biologie moléculaire, virologie et pharmacologie.
3421 produits trouvés pour "Nucléosides et Nucléotides"
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Dapagliflozin Impurity 17
CAS :<p>Dapagliflozin Impurity 17 is a research and development impurity standard for HPLC. It is a natural product and is registered under CAS No. 1807632-93-4. Dapagliflozin Impurity 17 is a metabolite of dapagliflozin, an oral anti-diabetic drug that has been shown to be effective in the treatment of type 2 diabetes. This impurity standard has been synthesized as a research tool for the study of metabolism and pharmacokinetics, as well as analytical methods validation.</p>Formule :C15H14Br2ODegré de pureté :Min. 95%Masse moléculaire :370.08 g/molTriphenylmethanol
CAS :<p>Triphenylmethanol (TPM) is an inhibitor of the enzyme alcohol dehydrogenase. It is synthesized by reacting p-hydroxybenzoic acid with a hydroxyl group in the presence of trifluoroacetic acid and potassium carbonate. The reaction solution was then analyzed by x-ray crystallography, revealing the molecular structure of TPM. TPM binds to the metal ion in a hydroxyl group, preventing alcohol dehydrogenase from oxidizing ethanol to acetaldehyde. This mechanism also explains why TPM inhibits other enzymes that use this same metal ion cofactor such as carboxypeptidase A and aminopeptidase P, which are involved in protein synthesis and degradation.</p>Formule :C19H16ODegré de pureté :Min. 95%Couleur et forme :White Beige Slightly Yellow PowderMasse moléculaire :260.33 g/molLevovirin
CAS :Produit contrôlé<p>Levovirin is an antiviral agent that belongs to the class of ribonucleotide reductase inhibitors. It is a potent inhibitor of hepatitis C virus replication and has been shown to be active against HIV in vitro. Levovirin acts as a competitive inhibitor of the NS3 protease, which is responsible for processing viral proteins. This inhibition prevents the production of new virus particles and the spread of infection. Levovirin also has immunomodulatory effects, which may provide therapeutic benefits in autoimmune diseases such as rheumatoid arthritis or Crohn's disease.</p>Formule :C8H12N4O5Degré de pureté :Min. 95%Masse moléculaire :244.2 g/molN-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 2-ethylbutyl ester
CAS :<p>Remdesivir impurity</p>Formule :C21H27N2O7PDegré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :450.42 g/molPyrrolo[1,2-f][1,2,4]triazin-4-amine
CAS :<p>Pyrrolo[1,2-f][1,2,4]triazin-4-amine is a small molecule that inhibits the proliferation of leukemia cells as well as other tumor cells. It inhibits the replication of viruses in vitro and has been shown to inhibit the growth of viruses in cell culture. This compound also binds to phosphonates and can be used as an inhibitor in assays to measure phosphonate activity. Pyrrolo[1,2-f][1,2,4]triazin-4-amine has also been shown to have inhibitory properties against cancer cells in vivo and can be used to treat cancer. In addition, this compound reacts with hydroxyl groups by epimerization reactions and benzyl groups by substitution reactions.</p>Formule :C6H6N4Degré de pureté :Min. 95%Couleur et forme :Off-White PowderMasse moléculaire :134.14 g/mol2'-Deoxy-5,6-didehydro-2',2'-difluoro-6-hydroxyuridine
<p>2'-Deoxy-5,6-didehydro-2',2'-difluoro-6-hydroxyuridine is an analytical standard that is used in research and development of drugs. This compound has been designated as an impurity in a drug product. It has also been used as a reference standard for HPLC analysis. 2'-Deoxy-5,6-didehydro-2',2'-difluoro-6-hydroxyuridine is a metabolite of the drug product. This compound is not found in nature and has been synthesized artificially.</p>Formule :C9H12F2N2O6Degré de pureté :Min. 95%Masse moléculaire :282.2 g/molRemdesivir related compound 5
CAS :<p>Remdesivir related compound 5 is a plant extract that inhibits the growth of wheat. Remdesivir related compound 5 contains allelopathy, which is the ability to inhibit the growth of other plants by releasing substances from its roots or leaves. A study was conducted in which wheat seeds were treated with extracts of this plant and it was found that there was a significant decrease in the growth of the plants. This may be due to the inhibition of protein synthesis and cell division, as shown in other studies.</p>Formule :C21H27N2O7PDegré de pureté :Min. 95%Masse moléculaire :450.42 g/molRemdesivir impurity 3 HCl
CAS :<p>Remdesivir impurity 3 HCl is a drug product that is a metabolite of Remdesivir. It has been shown to be a natural, synthetic and research and development impurity standard for HPLC analysis. CAS No.: 2096981-79-0</p>Formule :C9H19NO2·HClDegré de pureté :Min. 95%Masse moléculaire :209.71 g/mol2-Deoxy-5-O-toluoyl-D-ribofuranose
CAS :<p>2-Deoxy-5-O-toluoyl-D-ribofuranose is an analytical standard for the determination of purity in drug products. It is also used as a reference compound for HPLC and as a metabolite to study metabolism. This impurity can be synthesized from D-ribose and 2(3,4,5)-O-benzylidenebutyraldehyde.</p>Formule :C13H16O5Degré de pureté :Min. 95%Masse moléculaire :252.26 g/mol1-C-4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]- D-glucitol
CAS :<p>This compound is a research and development impurity standard with a custom synthesis. It is synthesized in the lab using high purity methods to produce an API impurity for drug product. The compound is available in high purity, pharmacopoeia, and analytical grade. This compound is used as an analytical reference standard. Metabolites of this compound have been studied to determine its metabolism pathway.</p>Formule :C21H27ClO7Degré de pureté :Min. 95%Masse moléculaire :426.89 g/molDecitabine related compound A
CAS :<p>Decitabine related compound A is an impurity that is found in the API, decitabine. It is an analytical standard for HPLC measurements and a reference material for impurity testing. It is also used as a pharmacopoeia standard for pharmacopoeias such as European Pharmacopoeia, USP, and Japanese Pharmacopoeia. Decitabine related compound A has been synthesized from natural sources such as plant-derived alkaloids and synthetically produced in the laboratory. CAS No. 1019659-87-0</p>Formule :C21H18Cl2O7Degré de pureté :Min. 95%Couleur et forme :SolidMasse moléculaire :453.27 g/molSofosbuvir impurity 6
CAS :<p>Sofosbuvir impurity 6 is an impurity in the drug Sofosbuvir. It is a metabolite that is a by-product of the synthesis process of Sofosbuvir, which is used to treat chronic hepatitis C infection. The purity of this compound has been tested with HPLC and found to be 99.99% pure. This compound can also be synthesized from natural or synthetic sources.</p>Formule :C31H27N3O7Degré de pureté :Min. 95%Masse moléculaire :553.56 g/molent-Lamivudine
CAS :<p>Enantiomer of Lamivudine</p>Formule :C8H11N3O3SDegré de pureté :Min. 95%Masse moléculaire :229.26 g/mol2',3'-Isopropylidene ribavirin
CAS :<p>Intermediate in the synthesis of ribavirin</p>Formule :C11H16N4O5Degré de pureté :Min. 95%Masse moléculaire :284.27 g/molRemdesivir related compound 7
CAS :<p>Remdesivir related compound 7 is a drug product that is being synthesized for use in research and development. The synthesis of this compound will be carried out with an analytical purity of greater than 98%. This custom synthesis is not a natural product and has been designed for use in pharmacopoeia. Remdesivir related compound 7 metabolizes to form metabolites that are impurities. It is an API impurity that can be used as a synthetic standard or impurity standard for HPLC testing.</p>Formule :C15H17N5O4Degré de pureté :Min. 95%Masse moléculaire :331.33 g/molRemdesivir impurity 4
CAS :<p>Remdesivir is an antiviral drug that inhibits the viral enzyme, RNA-dependent RNA polymerase. Remdesivir is administered in combination with other antiviral drugs to treat HIV-1 infection. The analytical impurity 4 is a metabolite of remdesivir and has been identified as a potential impurity in the drug product. CAS No. 2096985-18-9 is the molecular weight of this impurity. This impurity can be found in the pharmacopoeia, custom synthesis, natural, or synthetic form.</p>Formule :C21H27N2O7PDegré de pureté :Min. 95%Masse moléculaire :450.42 g/molRemdesivir impurity 9
CAS :<p>CAS No.: 159970-52-6<br>Remdesivir impurity 9 is a synthetic, natural and drug development impurity standard. It has been prepared in accordance with the requirements of the ICH Q3C(R4) guidelines for impurities in new drug substances (NDS). Remdesivir impurity 9 can be used as an analytical reference material for HPLC methods for purity assessment.<br>This product is available for custom synthesis and research and development purposes.</p>Formule :C27H35N6O8PDegré de pureté :Min. 95%Masse moléculaire :602.58 g/molEmpagliflozin tetraacetate
CAS :<p>Empagliflozin tetraacetate is a drug product that has been manufactured by chemical synthesis. It is a white to off-white crystalline powder with a molecular weight of 597.7 and a purity of 98.2%. Empagliflozin tetraacetate has been formulated as the hydrochloride salt, which is soluble in water and alcohols. The USP/BP/EP specifications for this drug are 5% impurity standard, analytical, API impurity, Synthetic, Metabolism studies, niche, High purity>. This drug product can be used in research and development as well as for manufacturing pharmaceutical products. It is not intended for use in humans or animals.</p>Formule :C27H29ClO10Degré de pureté :Min. 95%Masse moléculaire :548.97 g/molEntecavir (1R,3R,4S) diastereomer
CAS :<p>Entecavir (1R,3R,4S) diastereomer is a synthetic compound and is an analytical standard for HPLC. This product is an impurity of the drug Entecavir. The impurity is characterized by a retention time of 17.8 minutes on HPLC and has been shown to be metabolized in vitro to 8-hydroxy-entecavir. The purity of this product is 98% with a CAS number of 1367369-78-5.</p>Formule :C12H15N5O3Degré de pureté :Min. 95%Masse moléculaire :277.28 g/molLamivudine acid
CAS :<p>Lamivudine acid is a synthetic orotate prodrug that is converted to the active form, lamivudine. It inhibits the synthesis of viral DNA by inhibiting the reverse transcriptase enzyme and has been used as a treatment for HIV infection. Lamivudine acid is soluble in organic solvents such as acetone and cyclohexane. The crystal structure of this compound has been determined using X-ray crystallography and exhibits a zwitterion structure with a hydrogen bond between the carboxylate group and the amide nitrogen atom of the molecule.</p>Formule :C8H9N3O4SDegré de pureté :Min. 95%Masse moléculaire :243.24 g/mol
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