Nucléosides et Nucléotides
Les nucléosides sont des composés formés par une base azotée liée à un sucre (ribose ou désoxyribose). Lorsqu’un groupe phosphate est ajouté au nucléoside, un nucléotide est formé. Ces composés sont essentiels en biologie cellulaire, car les nucléotides sont les blocs fondamentaux de l’ADN et de l’ARN, responsables du stockage et de la transmission de l’information génétique. Les nucléosides ont des applications dans le traitement des maladies virales, en tant qu’inhibiteurs de la réplication virale. Les nucléotides, en plus de leur rôle structurel dans les acides nucléiques, interviennent dans les processus énergétiques, comme la synthèse de l’ATP.
Chez CymitQuimica, nous proposons une large gamme de nucléosides et de nucléotides essentiels à la recherche en biologie moléculaire, virologie et pharmacologie.
3421 produits trouvés pour "Nucléosides et Nucléotides"
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cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)- pyrimidinedione
CAS :<p>cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione is a drug product that has been custom synthesized for use as an analytical reference material and an impurity standard. It is a synthetic compound and has not been approved for any medicinal purposes. The pharmacopoeia it falls under is the United States Pharmacopeia (USP) and the European Pharmacopoeia (EP). cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione is used to determine the purity of active pharmaceutical ingredients in finished drug products. It can also be used as a research and development tool to study metabolism studies of natural compounds.</p>Formule :C8H9FN2O4SDegré de pureté :Min. 95%Masse moléculaire :248.23 g/molRemdesivir impurity 14
<p>Remdesivir impurity 14 is a research and development product that belongs to the class of drugs. It is a synthetic metabolite with high purity. Remdesivir impurity 14 meets the pharmacopoeia standard for drug products and drug development. It has been synthesized to be used as an analytical standard for HPLC analysis of remdesivir. This product also has niche applications in metabolism studies, because it is a natural metabolite with its own metabolic pathway.</p>Formule :C18H18N5O7PDegré de pureté :Min. 95%Masse moléculaire :447.34 g/molRemdesivir impurity 5
CAS :<p>Remdesivir impurity 5 is a metabolite that is generated in the body following metabolism and excretion of remdesivir. It has been shown to be present in urine, plasma, and cerebrospinal fluid following administration of remdesivir. Remdesivir impurity 5 binds to the active site of HIV reverse transcriptase with a Kd value of 0.5 nM. The chemical name for this compound is (5R)-3-[[3-[(2S,4R)-2-amino-4-(2-methylpropyl)piperidin-1-yl]-1H-indol-6-yl]carbonyl]benzoic acid methyl ester.</p>Formule :C21H27N2O7PDegré de pureté :Min. 95%Masse moléculaire :450.42 g/mol3'-[3-(3-Azido-2,3-dideoxy-b-D-erythro-pentofuranosyl)-3,6-dihydro-5-methyl-2,6-dioxo-1(2H)-pyrimidinyl]-3'-deoxy-thymidine
CAS :<p>3'-[3-(3-Azido-2,3-dideoxy-b-D-erythro-pentofuranosyl)-3,6-dihydro-5-methyl-2,6-dioxo-1(2H)-pyrimidinyl]-3'-deoxythymidine is an analytical standard used in the R&D and drug development of 3'-azido derivatives of thymidine. It is a synthetic intermediate that has been shown to be a potent inhibitor of human immunodeficiency virus type 1 (HIV) replication and to inhibit intracellular HIV type 2 (HIV2) production in cultured cells. 3'-[3-(3-Azido-2,3,-dideoxy--b erythro--pentofuranosyl)-3,6--dihydro--5--methyl--2,6--dioxo--1(2H)--pyrimidinyl]-</p>Formule :C20H25N7O8Degré de pureté :95%NmrMasse moléculaire :491.45 g/molAciclovir EP impurity J
CAS :<p>Aciclovir EP impurity J is a drug product that is used as an analytical standard in HPLC. Aciclovir EP impurity J is the natural metabolite of aciclovir, which is an antiviral drug. It is not active against herpesviruses but has been shown to inhibit the growth of human cells infected with cytomegalovirus. Aciclovir EP impurity J has been studied for its effects on drug metabolism and pharmacokinetics. Aciclovir EP impurity J has been shown to be excreted primarily in urine, with some excretion in the feces.</p>Formule :C14H16N10O4Degré de pureté :Min. 95%Masse moléculaire :388.34 g/molRemdesivir impurity 1
CAS :<p>Remdesivir impurity 1 is a drug product, analytical and Metabolism studies. It is a custom synthesis, Impurity standard, Synthetic and Drug development. Remdesivir impurity 1 is an API impurity that is a natural and has CAS No. 1355049-95-4. The HPLC standard of Remdesivir impurity 1 is high purity and pharmacopoeia.</p>Formule :C12H13N5O4Degré de pureté :Min. 95%Masse moléculaire :291.26 g/mol1-(2-Deoxy-β-D-xylofuranosyl)-5-methyluracil
CAS :<p>1-(2-Deoxy-beta-D-xylofuranosyl)-5-methyluracil (1DXP) is a nucleoside that inhibits the enzyme UDP glucose pyrophosphorylase. This enzyme is involved in the synthesis of uridine nucleotides, which are required for RNA and DNA synthesis. 1DXP has been shown to be effective against hepatitis B virus and lymphocytic leukemia cells in vitro. The mechanism of action of 1DXP is not well understood, but it may be related to the inhibition of protein synthesis or cellular metabolism. It may also inhibit the enzyme amino transferase, which is important for the synthesis of aromatic amino acids such as phenylalanine and tyrosine.</p>Formule :C10H14N2O5Degré de pureté :Min. 95%Masse moléculaire :242.23 g/molSarcolysine hydrochloride
CAS :<p>Sarcolysine hydrochloride, also known as Melphalan HCl, is a nitrogen mustard and alkylating agent that has been studied for use in multiple myeloma therapy.</p>Formule :C13H19Cl3N2O2Couleur et forme :SolidMasse moléculaire :341.66Adefovir diphosphate
CAS :<p>Adefovir monophosphate: antiviral ANP active against HBV, herpes; ntRTI for hepatitis B, not HIV-1 effective.</p>Formule :C8H13N5O7P2Couleur et forme :SolidMasse moléculaire :353.17Diapocynin
CAS :<p>Diapocynin (Dehydrodiacetovanillone), a dimer of Apocynin, acts as an orally administered inhibitor of NADPH oxidase.</p>Formule :C18H18O6Couleur et forme :SolidMasse moléculaire :330.33Creatine monohydrate
CAS :<p>Creatine monohydrate powers ATP for short, high-intensity activities in muscles and brain.</p>Formule :C4H11N3O3Degré de pureté :99.87%Couleur et forme :White SolidMasse moléculaire :149.15S07-2010
CAS :<p>S07-2010 is a pan-Aldo-Keto Reductase 1C3 (AKR1C3) inhibitor with potential anti-cancer activity, inducing apoptosis in A549/DDP cells.</p>Formule :C19H21N3O3SDegré de pureté :98.13%Couleur et forme :SolidMasse moléculaire :371.45LY450108
CAS :<p>LY450108 is a potentiator of the AMPA receptor that can be used in Parkinson's disease studies.</p>Formule :C19H22F2N2O3SDegré de pureté :98.87% - 99.91%Couleur et forme :SolidMasse moléculaire :396.45CNV-2197944
CAS :<p>CNV-2197944 is a novel, small molecule, state-dependent calcium channel blocker, designed to selectively inhibit highly active Cav2.2 channels.</p>Formule :C19H20F3N3O3SCouleur et forme :SolidMasse moléculaire :427.44Galidesivir triphosphate
CAS :<p>Galidesivir triphosphate halts viral RNA replication by inhibiting RDRP and NS5B, and combats Ebola in mice; derived from prodrug Galidesivir.</p>Formule :C11H18N5O12P3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :505.21(S)-AMPA
CAS :<p>(S)-AMPA is an active isomer of AMPA and a selective agonist of AMPA.</p>Formule :C7H10N2O4Couleur et forme :SolidMasse moléculaire :186.17(R)-Oxiracetam
CAS :<p>(R)-Oxiracetam is the (R)-enantiomer of the nootropic drug oxiracetam. Oxiracetam is a nootropic drug of the racetam family and stimulant.</p>Formule :C6H10N2O3Couleur et forme :SolidMasse moléculaire :158.16Apadenoson
CAS :<p>Apadenoson: potent A2 agonist, A3 inhibitor (IC 45 nM), anti-inflammatory, for neurological research.</p>Formule :C23H30N6O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :486.52Gemcitabine monophosphate
CAS :<p>R306465, a potent HDAC1/8 inhibitor, has broad antitumor effects (IC50: 30-300 nM) on solid and blood cancers.</p>Formule :C9H12F2N3O7PCouleur et forme :SolidMasse moléculaire :343.18Peldesine
CAS :<p>Peldesine (BCX 34), an oral purine nucleoside phosphorylase blocker, halts T-cell growth; used in CTCL, psoriasis, HIV research. IC50: 800 nM.</p>Formule :C12H11N5ODegré de pureté :99.27% - 99.9%Couleur et forme :SolidMasse moléculaire :241.25
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