Nucléosides et Nucléotides
Les nucléosides sont des composés formés par une base azotée liée à un sucre (ribose ou désoxyribose). Lorsqu’un groupe phosphate est ajouté au nucléoside, un nucléotide est formé. Ces composés sont essentiels en biologie cellulaire, car les nucléotides sont les blocs fondamentaux de l’ADN et de l’ARN, responsables du stockage et de la transmission de l’information génétique. Les nucléosides ont des applications dans le traitement des maladies virales, en tant qu’inhibiteurs de la réplication virale. Les nucléotides, en plus de leur rôle structurel dans les acides nucléiques, interviennent dans les processus énergétiques, comme la synthèse de l’ATP.
Chez CymitQuimica, nous proposons une large gamme de nucléosides et de nucléotides essentiels à la recherche en biologie moléculaire, virologie et pharmacologie.
3421 produits trouvés pour "Nucléosides et Nucléotides"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
Hypoxanthine
CAS :Produit contrôlé<p>Applications A naturally occurring purine derivative. Pharmaceuticals, Intermediates & Fine Chemicals<br>References Jansen, R., et al.: Clin. Biochem., 38, 362 (2005), Vorst, O., et al.: Metabolomics, 1, 169 (2005), Want, E., et al.: ChemBioChem., 6, 1941 (2005), van der Werf, M., et al.: Anal. Biochem., 370, 17 (2007),<br></p>Formule :C5H4N4OCouleur et forme :NeatMasse moléculaire :136.11Ademethionine 1,4-Butanedisulfonate
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Ademethionine 1,4-Butanedisulfonate is used in the synthesis of sulfonio-adenosyl-L-methionine (SAMe) salts.<br></p>Formule :C15H22N6O5S·3C4H10O6S2Couleur et forme :NeatMasse moléculaire :1451.62epi-Canagliflozin
CAS :Produit contrôlé<p>Applications epi-Canagliflozin is an epimeric impurity of Canagliflozin which is a sodium/glucose cotransporter 2 (SGLT2) inhibitor and is used in the treatment of type 2 diabetes and obesity.<br>References Chao, E. et al.: Drug Fut., 36, 351 (2011); Sha, S. et al.: Diab. Obes. Metab., 13, 669 (2011); Kipnes, M.S.: Clin. Invest., 1, 145 (2011);<br></p>Formule :C24H25FO5SCouleur et forme :NeatMasse moléculaire :444.52(1R,2R,5R)-2-Isopropyl-5-methylcyclohexanol
CAS :<p>Applications (1R,2R,5R)-2-Isopropyl-5-methylcyclohexanol is used in the tetrahydropyranylation of alcohols.<br>References Magyar, A. et al.: Catal. Lett., 145, 1876 (2015);<br></p>Formule :C10H20OCouleur et forme :NeatMasse moléculaire :156.275-Chlorocytidine
CAS :Produit contrôléFormule :C9H12ClN3O5Couleur et forme :NeatMasse moléculaire :277.66Creatinine-d3
CAS :Produit contrôlé<p>Applications Labelled Creatinine. The end product of creatine catabolism. Normal constituent of urine. Also found together with creatine in muscle tissues and blood. Occurs in all soils and in grain seeds and other vegetable matter. Has been found in certain fish and in crab meat extract.<br>References Folin, et al.: J. Biol. Chem., 17, 463 (1914),<br></p>Formule :C42H3H4N3OCouleur et forme :Off-WhiteMasse moléculaire :116.14Adenosine-3'-monophosphate
CAS :Produit contrôlé<p>Applications Adenosine-3'-monophosphate (cas# 84-21-9) is a useful research chemical.<br></p>Formule :C10H14N5O7PCouleur et forme :NeatMasse moléculaire :347.22125-(Hydroxymethyl)-2’-deoxycytidine
CAS :Produit contrôlé<p>Applications 4-(Hydroxymethyl)-2’-deoxycytidine is a modified pyrimidine that is capable of producing interstrand cross-links in duplex DNA. 4-(Hydroxymethyl)-2’-deoxycytidine can be analyzed to quantify DNA hydroxymethylation levels in biological samples<br>References Peng, X. et al.: J. Am. Chem. Soc., 130, 10299 (2008); Berkner, K. et al.: J. Biol. Chem., 252, 3185 (1977); Le, T. et al.: Anal. Biochem., 412, 203 (2011);<br></p>Formule :C10H15N3O5Couleur et forme :NeatMasse moléculaire :257.241’-epi-Entecavir
CAS :Produit contrôlé<p>Impurity Entecavir EP Impurity A<br>Applications An epimeric impurity of the antiviral drug Entecavir (E558900).<br></p>Formule :C12H15N5O3Couleur et forme :NeatMasse moléculaire :277.2796-Hydroxy-2,4,5-triaminopyrimidine, Sulfate
CAS :Produit contrôlé<p>Applications 6-Hydroxy-2,4,5-triaminopyrimidine, Sulfate (cas# 35011-47-3) is a compound useful in organic synthesis.<br></p>Formule :C4H7N5O·H2O·H2O4SCouleur et forme :NeatMasse moléculaire :257.22Peramivir
CAS :<p>Peramivir is a neuraminidase inhibitor used to treat influenza by preventing virus release from cells.</p>Formule :C15H28N4O4Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :328.41D-Ribose
CAS :Produit contrôlé<p>Applications D-Ribose is produced by microorganism fermentation of glucose in a fermentation culture medium without adding calcium carbonate.<br>References Ostrowski, S., et al.: Science, 305, 71 (2004), Vavilin, D., et al.: Biochim. Biophys. Acta, 1708, 91 (2005), Fletcher, J., et al.: Anal. Chem., 79, 2199 (2007), Weissleder, R., et al.: Nature, 452, 580 (2008),<br></p>Formule :C5H10O5Couleur et forme :NeatMasse moléculaire :150.132-Phenylamino Adenosine
CAS :Produit contrôlé<p>Applications A selective A2-adenosine receptor agonist. Coronary vasodilator, antihypertensive and antipsychotic following systemic administration in vivo.<br>References Martin, et al.: Pharmacol. Biochem. Behav., 45, 951 (1993<br></p>Formule :C16H18N6O4Couleur et forme :NeatMasse moléculaire :358.35Adenosine 2’,3’-Cyclic Phosphate Triethylammonium Salt
CAS :<p>Applications A 2',3'-cyclic nucleotide phosphodiester.<br>References Voegtli, W., et al.: Biochemistry, 39, 15365 (2000), Bernstein, N., et al.: Mol. Cell, 17, 657 (2005), Blondal, T., et al.: J. Biol. Chem., 280, 5188 (2005), Shenoy, A., et al.: J. Mol. Biol., 365, 211 (2007),<br></p>Formule :C16H27N6O6PCouleur et forme :NeatMasse moléculaire :430.42’-Deoxy-3’,5’-di-O-benzoyl-2’,2’-difluorocytidine
CAS :Produit contrôléFormule :C23H19F2N3O6Couleur et forme :NeatMasse moléculaire :471.418-Cyclopentyl-1,3-dipropylxanthine
CAS :Produit contrôlé<p>Applications DPCPX is a potent and very selective A1-adenosine receptor antagonist, with a Ki of 0.46 nM for A1 receptors in rat whole-brain membranes. Its 740-fold A1-selectivity is the highest reported for an adenosine antagonist.<br>References Gessi, S., et al.: Mol. Pharmacol., 67, 2137 (2005), Minor, T.R., et al.: Behav. Neurosci., 122, 1236 (2008), Gracia, E., et al.: J. Neurochem., 107, 161 (2008), Gessi, S., et al.: Biochem. Pharmacol., 75, 562 (2008),<br></p>Formule :C16H24N4O2Couleur et forme :NeatMasse moléculaire :304.391-Chloro-2-[(4-ethoxyphenyl)methyl]benzene
CAS :Produit contrôléFormule :C15H15ClOCouleur et forme :NeatMasse moléculaire :246.732Adenosine Monophosphate (mixture of 2'(3')-phosphate isomers)-13C5 Sodium Salt
CAS :Produit contrôlé<p>Applications Labelled AMP mixture<br>References Jackson, E.K. et al.: Hypertension, 56, 151 (2010); Jackson, E.K. et al: J. Bio. Chem., 284, 33097 (2009);<br></p>Formule :C513C5H14N5O7P•x(Na)Couleur et forme :NeatMasse moléculaire :352.182299Lamivudine-15N2,13C
CAS :Produit contrôléFormule :CC7H1115N2NO3SCouleur et forme :White To BeigeMasse moléculaire :232.241'-Epi 2',2'-Difluoro-2'-deoxyuridine
CAS :<p>Applications The epimer of the degradation product of Gemcitabine (G305000), a new antitumor agent.<br>References Anliker, S.L., et al.: J. Pharmaceut. Sci., 83, 716 (1994),<br></p>Formule :C9H10F2N2O5Couleur et forme :Light Yellow SolidMasse moléculaire :264.18Nicotinic Acid Riboside
CAS :Produit contrôlé<p>Applications An effective agent for increasing nicotinamide adenine dinucleotide (NAD) concentrations in mammalian cells.<br>References Yang, T. et al.: J. Med. Chem., 50, 6458 (2007);<br></p>Formule :C11H13NO6Couleur et forme :NeatMasse moléculaire :255.22Folic Acid-d2
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications A vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, it also acts as a cofactor in biological reactions involving folate.<br>References Xu, L., et al.: Mol. Pharm., 7, 1311 (2010), Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010), Alshatwi, A., et al.: Food, Chem., Toxicol., 48, 1881 (2010), McKay, D., et al.: Nut. J., 9 (2010),<br></p>Formule :C19H17D2N7O6Couleur et forme :NeatMasse moléculaire :443.415-Methoxyuracil
CAS :Produit contrôlé<p>Impurity Fluorouracil EP Impurity D<br>Applications 5-Methoxyuracil (Fluorouracil EP Impurity D) is methoxylated uracil, a component of nucleid acid. 5-Methoxyuracil is used in the preparation of nucleosides.<br>References Vorbrueggen, H. et al.: Chem. Ber., 114, 1279 (1981); Novacek, A. et al.: Coll. Czech. Chem. Comm., 32, 1045 (1967);<br></p>Formule :C5H6N2O3Couleur et forme :NeatMasse moléculaire :142.11Eritadenine
CAS :Produit contrôlé<p>Applications Hypocholesterolemic isolated from shiitake mushrooms, effecting phospholipid and linoleic acid metabolisms. Specifically, Eritadenine is a potent inhibitor of S-adenosyl-L-homocysteine hydrolase (SAHH), decreasing total cholesterol levels in plasma.<br>References Fukada, S., et al.: J. Nut., 136, 2797 (2006), Vilar, S., et al.: J. Med. Chem., 49, 1118 (2006), Yamada, T., et al.: Biochem. Pharmacol., 73, 981 (2007), Enman, J., et al.; J. Agric. Food Chem., 56, 2609 (2008),<br></p>Formule :C9H11N5O4Couleur et forme :Off White SolidMasse moléculaire :253.212',3'-Anhydroinosine
CAS :Produit contrôlé<p>Impurity Didanosine EP Impurity E<br>Applications 2',3'-Anhydroinosine (Didanosine EP Impurity E) is an impurity of the antiviral drug 2’,3’-Dideoxyinosine (D440950).<br>References Rao, D.V.N. et al.: J. Pharmac. Biomed.Anal., 45, 516 (2007);<br></p>Formule :C10H10N4O4Couleur et forme :NeatMasse moléculaire :250.21Acyclovir Acetate
CAS :<p>Impurity Valaciclovir EP Impurity I/ Aciclovir USP Related Compound A<br>Applications Acyclovir Acetate (Valaciclovir EP Impurity I) is an Acyclovir (A192400) impurity, Aciclovir EP Impurity A<br>References Goskonda, V., et al.: J. Pharm. Sci., 88, 180 (1999); Chang, J., et al.: Pharm. Res., 17, 670 (2000),<br></p>Formule :C10H13N5O4Couleur et forme :NeatMasse moléculaire :267.24(5-Bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone
CAS :Produit contrôléFormule :C15H12BrClO2Couleur et forme :NeatMasse moléculaire :339.6122-Amino-6-chloropurine
CAS :<p>Impurity Famciclovir USP Related Compound F<br>Applications Famciclovir USP Related Compound F<br></p>Formule :C5H4ClN5Couleur et forme :YellowMasse moléculaire :169.57(S)-N-[4-[[((S)-2-Amino-6,7,8,9-tetrahydro-8-methyl-4,9-dioxo-4H-pyrazino[1,2-a]-1,3,5-triazin-7-yl)
<p>Applications An impurity of Levomefolate (L375720), the natural form of folic acid.<br>References Verlinde, P.H.C.., et al.: J. Agr. Food. Chem., 57, 6803 (2009); Whiteley, J.M., et al.: Biochem. Biophy. Res. Comm., 101, 1259 (1981);<br></p>Formule :C20H23N7O7Couleur et forme :NeatMasse moléculaire :473.44Dapagliflozin-d5
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Dapagliflozin-D5 is a labelled analogue of Dapagliflozin (D185370), a selective sodium-glucose cotransporter-2 inhibitor that reduces renal glucose reabsorption and is used to treat patients with type 2 diabetes.<br>References List, J., et al.: Diabetes Care, 32, 650 (2009); Meng, W., et al.: J. Med. Chem., 51, 1145 (2008); Wilding, J., et al.: Diabetes Care, 32, 1656 (2009)<br></p>Formule :C21H20D5ClO6Couleur et forme :White To Off-WhiteMasse moléculaire :413.9Gemcitabine Monophosphate
CAS :<p>Applications Gemcitabine Monophosphate is a gemcitabine derivative. It is an antineoplastic agent.<br>References Balzarini, J., et al.: Biochem. Pharmacol., 37, 897 (1988), Abbruzzese, J., et al.: Investig. New Drugs, 7, 195 (1989), Balzarini, J., et al.: J. Biol. Chem., 264, 6127 (1989), Chu, C., et al.: Antimicrob. Agents Chemother., 39, 979 (1995)<br></p>Formule :C9H12F2N3O7PCouleur et forme :White To Off-WhiteMasse moléculaire :343.189-Oxofolic Acid
CAS :<p>Stability Hygroscopic<br>Applications 9-Oxofolic Acid is a derivative of Folic Acid (F680300) which is a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA. Folic Acid also acts as a cofactor in biological reactions involving folate.<br>References Xu, L., et al.: Mol. Pharm., 7, 1311 (2010), Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010), Alshatwi, A., et al.: Food, Chem., Toxicol., 48, 1881 (2010), McKay, D., et al.: Nut. J., 9 (2010),<br></p>Formule :C19H17N7O7Couleur et forme :NeatMasse moléculaire :455.38Dihydroxy Melphatalan
CAS :Produit contrôlé<p>Applications Dihydroxy Melphatalan is an analogue of Melphalan (M216900), an antineoplastic.<br>References Ross, W.C.J., et al.: Biochem. Pharmacol., 13, 969 (1964); Donelli, M.G., et al.: J. Pharm. Pharmacol., 18, 760 (1966), Furner, R.L., et al.: Cancer Treat. Rep., 64, 559 (1980);<br></p>Formule :C13H20N2O4Couleur et forme :NeatMasse moléculaire :268.31Folic Acid-d4
CAS :Produit contrôlé<p>Applications A vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, it also acts as a cofactor in biological reactions involving folate.<br>References Xu, L., et al.: Mol. Pharm., 7, 1311 (2010), Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010), Alshatwi, A., et al.: Food, Chem., Toxicol., 48, 1881 (2010), McKay, D., et al.: Nut. J., 9 (2010),<br></p>Formule :C192H4H15N7O6Couleur et forme :NeatMasse moléculaire :445.425-(Methyl-d3)tetrahydrofolic Acid (Mixture of Diastereomers)
CAS :Produit contrôléFormule :C20H22D3N7O6Couleur et forme :NeatMasse moléculaire :462.47T-705 Ribofuranose
CAS :<p>Applications T-705 Ribofuranose is a reagent used for the preparation of pyrazine-ribofuranose derivatives as antiviral agents that are useful in the treatment of viral infections.<br>References Zhong, B., et al.: Faming Zhuanli Shenqing, 2014:924257 (2014)<br></p>Formule :C10H12FN3O6Couleur et forme :NeatMasse moléculaire :289.22Ganciclovir-d5
CAS :Produit contrôléFormule :C9H8D5N5O4Couleur et forme :WhiteMasse moléculaire :260.266-Mercaptopurine Disulfide
CAS :Produit contrôlé<p>Applications 6-Mercaptopurine Disulfide is an impurity of 6-Mercaptopurine (M225450, monohydrate) which is an immunosuppressive drug used to treat leukemia. It is also used for pediatric non-Hodgkin’s lymphoma, polycythemia vera, and psoriatic arthritis.<br>References Zeng, H., et al.: Biochem. Pharmacol., 68, 911 (2004)<br></p>Formule :C10H6N8S2Couleur et forme :Yellow To Dark YellowMasse moléculaire :302.343'-[3-(3-Azido-2,3-dideoxy-β-D-erythro-pentofuranosyl)-3,6-dihydro-5-methyl-2,6-dioxo-1(2H)-pyrimidinyl]-3'-deoxy-thymidine
CAS :Produit contrôlé<p>Impurity Zidovudine USP Related Compound G<br>Stability Light Sensitive<br>Applications 3'-[3-(3-Azido-2,3-dideoxy-β-D-erythro-pentofuranosyl)-3,6-dihydro-5-methyl-2,6-dioxo-1(2H)-pyrimidinyl]-3'-deoxy-thymidine (Zidovudine USP Related Compound G) is used in the biological studies and in the preparation of N-3-substituted thymidine nucleosides as virucides as it has anti-HIV activity.<br>References Adams, D.R., et al.: J. Med. Chem., 40, 1550 (1997), Mainardes, R., et al.: J. Pharm. Sci., 98, 257 (2009),<br></p>Formule :C20H25N7O8Couleur et forme :NeatMasse moléculaire :491.45N-Acetyl Glyphosate
CAS :<p>Stability Very Hygroscopic<br>Applications A metabolite of the pesticide Glyphosphate (G765000).<br>References Siehl, D.L. et al.: J. Biol. Chem., 282, 11446 (2007); Env. Prot. Agen. EPA: Fed. Reg., 74, 67129 (2009);<br></p>Formule :C5H10NO6PCouleur et forme :White To Off-WhiteMasse moléculaire :211.11Adenosine-2’,3’-cyclic Monophosphate Sodium Salt
CAS :Produit contrôléFormule :C10H11N5O6P·NaCouleur et forme :NeatMasse moléculaire :351.188Gemcitabine Triphosphate Ditriethylamine
CAS :Produit contrôlé<p>Stability Hygroscopic, Temperature Sensitive<br>Applications Gemcitabine Triphosphate is a phosphorylated metabolite of Gemcitabine (G305000), an antineoplastic agent.<br>References Kennedy., E.P., et al.: J. Biol. Chem., 222, 193 (1956),<br></p>Formule :C21H44F2N5O13P3Couleur et forme :NeatMasse moléculaire :705.52Canagliflozin 3-Glucuronide
Produit contrôlé<p>Applications Canagliflozin 3-glucuronide is a derivative of Canagliflozin (C175190). Canagliflozin is a sodium-glucose cotransporter 2 inhibitor that is used to treat patients with type 2 diabetes. Canagliflozin lowers blood glucose by increasing the amount of glucose that exits the body through urinary excretion.<br>References Devineni, D., et al.: Diab. Obes. Metab., 14, 539 (2012); Nicolle, L., et al.: Curr. Med. Res. Opin., 28, 1167 (2012)<br></p>Formule :C30H33FO11SCouleur et forme :NeatMasse moléculaire :620.64(-)-Inosine-1',2',3',4',5'-13C5
CAS :<p>Stability Hygroscopic<br>Applications Isotope labelled analogue of (-)-Inosine (I661000), compound that exhibits neuroprotective properties by improving axonal wiring and has also been used to treat stroke patients to restore neural function.<br>References Vandemeulebroucke, A., et al.: Biochem., 49, 8999 (2010), Nestor, G., et al.: J. Agric. Food Chem., 58, 10799 (2010),<br></p>Formule :C513C5H12N4O5Couleur et forme :White To Off-WhiteMasse moléculaire :273.19Acetoguanide
CAS :Produit contrôlé<p>Applications Acetoguanide is a degradation product of the sulfonylurea herbicide Iodosulfuron.<br>References Pramauro, E., et al.: Environ. Sci. Technol., 27, 1790 (1993); Rouchard, J., et al.: Toxicol. Environ. Chem., 85, 103 (2003); Brigante, M., et al.: J. Agric. Food Chem., 53, 5347 (2005);<br></p>Formule :C4H6N4OCouleur et forme :White To Light YellowMasse moléculaire :126.12Adenosine 5'-Monophosphate-5',5''-d2 Disodium Salt
CAS :Produit contrôlé<p>Applications Isotope labelled analogue of Adenosine 5’-Monophosphate (A281790), a nucleotide that is used as a monomer in RNA.<br>References Watanabe, M., et al.: Arch. Dermatol., 127, 1689 (1991); Engelke, M., et al.: Br. J. Dermatol., 137, 219 (1997)<br></p>Formule :C10H10D2N5Na2O7PCouleur et forme :NeatMasse moléculaire :393.2Cytidine 2':3'-cyclic Monophosphate Monosodium Salt (>85%)
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Cytidine 2':3'-cyclic Monophosphate Monosodium Salt is a key compound in the enzymic synthesis of short oligoribonucleotides. Reagent in the amine catalyzed solid-phase synthesis of oligonucleotides.<br>References Gusenkova, N. M., et al.: Zhurnal Obshchei Khimii, 46, 939 (1976); Tomasz, J., et al.: Nucleic Acid Chem., 2, 875 (1978)<br></p>Formule :C9H11N3NaO7PDegré de pureté :>85%Couleur et forme :NeatMasse moléculaire :327.16(+)-Isomenthol
CAS :<p>Applications (+)-Isomenthol is a reagent that has been used in the preparation of a phosphine activator.<br>References Rajendran., K.V., et. al.: Tetrahedron Lett., 54, 7009 (2013)<br></p>Formule :C10H20OCouleur et forme :White To Off-WhiteMasse moléculaire :156.27(2R,5S)-L-Menthol-5-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylate
CAS :Produit contrôlé<p>Applications A Lamivudine (L172500) intermediate.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chang, C., et al.: J. Biol. Chem., 267, 13938 (1992), Jeong, L., et al.: J. Med. Chem., 36, 181 (1993).<br></p>Formule :C18H27N3O4SCouleur et forme :NeatMasse moléculaire :381.49N2,9-Diacetylguanine
CAS :Produit contrôlé<p>Impurity Acicclovir EP Impurity L<br>Applications N2,9-Diacetylguanine (Acicclovir EP Impurity L) is used to synthesize acyclic analogues of deoxyguanosine.<br>References Martin, J. C., et al.: J Med Chem. 26, 759 (1983)<br></p>Formule :C9H9N5O3Couleur et forme :NeatMasse moléculaire :235.20
![1-Chloro-2-[(4-ethoxyphenyl)methyl]benzene](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FC293450.webp&w=3840&q=75)
![(S)-N-[4-[[((S)-2-Amino-6,7,8,9-tetrahydro-8-methyl-4,9-dioxo-4H-pyrazino[1,2-a]-1,3,5-triazin-7-y…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FA629750.webp&w=3840&q=75)
