
Nucléosides et Nucléotides
3485 produits trouvés pour "Nucléosides et Nucléotides"
Remdesivir impurity 14
Remdesivir impurity 14 is a research and development product that belongs to the class of drugs. It is a synthetic metabolite with high purity. Remdesivir impurity 14 meets the pharmacopoeia standard for drug products and drug development. It has been synthesized to be used as an analytical standard for HPLC analysis of remdesivir. This product also has niche applications in metabolism studies, because it is a natural metabolite with its own metabolic pathway.Formule :C18H18N5O7PDegré de pureté :Min. 95%Masse moléculaire :447.34 g/molLevovirin
CAS :Produit contrôléLevovirin is an antiviral agent that belongs to the class of ribonucleotide reductase inhibitors. It is a potent inhibitor of hepatitis C virus replication and has been shown to be active against HIV in vitro. Levovirin acts as a competitive inhibitor of the NS3 protease, which is responsible for processing viral proteins. This inhibition prevents the production of new virus particles and the spread of infection. Levovirin also has immunomodulatory effects, which may provide therapeutic benefits in autoimmune diseases such as rheumatoid arthritis or Crohn's disease.Formule :C8H12N4O5Degré de pureté :Min. 95%Masse moléculaire :244.2 g/mol2'-Epi-lamivudine
CAS :2'-Epi-lamivudine is a chiral, racemic mixture of the two enantiomers of lamivudine. The synthesis and purification of 2'-epi-lamivudine is achieved by using a chiralpak column to separate the optical isomers from each other and then an immunoaffinity column to remove the undesired enantiomer (the S-enantiomer). The final product is a mixture of both enantiomers in a 1:1 ratio, which has been shown to have antiviral activity against HIV. 2'-Epi-lamivudine has been shown to be more potent than its parent compound lamivudine and is less toxic. This antiviral agent inhibits HIV replication by inhibiting reverse transcriptase, which is an enzyme that synthesizes viral DNA from viral RNA. It also has anti-inflammatory properties that may be due to inhibition of prostaglandin synthesis.Formule :C8H11N3O3SDegré de pureté :Min. 95%Masse moléculaire :229.26 g/mol5'-O-Acetyl ribavirin
CAS :Produit contrôlé5'-O-Acetyl ribavirin is an impurity of ribavirin, a drug product that belongs to the group of antiviral drugs. It is used in the treatment of chronic hepatitis C and influenza. 5'-O-Acetyl ribavirin is found in natural products such as plants, honey, and wine. The CAS number for this impurity is 58151-87-4. This compound can be synthesized through custom synthesis or by using a high purity HPLC standard as an impurity standard.Formule :C10H14N4O6Degré de pureté :Min. 95%Masse moléculaire :286.24 g/mol1-(2-Deoxy-beta-D-xylofuranosyl)-5-methyluracil
CAS :1-(2-Deoxy-beta-D-xylofuranosyl)-5-methyluracil (1DXP) is a nucleoside that inhibits the enzyme UDP glucose pyrophosphorylase. This enzyme is involved in the synthesis of uridine nucleotides, which are required for RNA and DNA synthesis. 1DXP has been shown to be effective against hepatitis B virus and lymphocytic leukemia cells in vitro. The mechanism of action of 1DXP is not well understood, but it may be related to the inhibition of protein synthesis or cellular metabolism. It may also inhibit the enzyme amino transferase, which is important for the synthesis of aromatic amino acids such as phenylalanine and tyrosine.Formule :C10H14N2O5Degré de pureté :Min. 95%Masse moléculaire :242.23 g/mol4-Amino-1-[3,5-di-O-(4-chlorobenzoyl)-2-deoxy-α-D-ribofuranosyl]-1,3,5-triazin-2(1H)-one
CAS :4-Amino-1-[3,5-di-O-(4-chlorobenzoyl)-2-deoxy-α-D-ribofuranosyl]-1,3,5-triazin-2(1H)-one (4AAT) is an analytical chemical that is used for research and development purposes. 4AAT is a metabolite of the antibiotic ampicillin and has been identified as an impurity in the drug product. It can be synthesized from 2-(4'-chlorophenyl)benzaldehyde, 3,5'-di-O-(4'-chlorobenzoyl)-2',3'-dideoxyribose and sodium azide in a two step process with 98% purity. 4AATs are also found to be present in natural products such as honey or sugar cane juice.
Formule :C22H18Cl2N4O6Degré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :505.31 g/molDecitabine related compound A
CAS :Decitabine related compound A is an impurity that is found in the API, decitabine. It is an analytical standard for HPLC measurements and a reference material for impurity testing. It is also used as a pharmacopoeia standard for pharmacopoeias such as European Pharmacopoeia, USP, and Japanese Pharmacopoeia. Decitabine related compound A has been synthesized from natural sources such as plant-derived alkaloids and synthetically produced in the laboratory. CAS No. 1019659-87-0Formule :C21H18Cl2O7Degré de pureté :Min. 95%Couleur et forme :SolidMasse moléculaire :453.27 g/mol2-Deoxy-5-O-toluoyl-D-ribofuranose
CAS :2-Deoxy-5-O-toluoyl-D-ribofuranose is an analytical standard for the determination of purity in drug products. It is also used as a reference compound for HPLC and as a metabolite to study metabolism. This impurity can be synthesized from D-ribose and 2(3,4,5)-O-benzylidenebutyraldehyde.Formule :C13H16O5Degré de pureté :Min. 95%Masse moléculaire :252.26 g/molRemdesivir related compound 12
CAS :Remdesivir related compound 12 is a synthetic drug product. It is an impurity standard used for the production of the active pharmaceutical ingredient, remdesivir. The substance is a custom synthesis and can be synthesized to meet customer specifications. Remdesivir related compound 12 has been studied in animal models for metabolism studies and human pharmacokinetic studies. This substance is also used for research and development, as well as niche drug development.
Formule :C21H27N2O7PDegré de pureté :Min. 95%Masse moléculaire :450.42 g/mol1'-Epi gemcitabine 3',5'-dibenzoate
CAS :1'-Epi-Gemcitabine 3',5'-dibenzoate is an analytical standard that is used in the drug development process. It is also a high purity, API impurity, HPLC standard, and drug product. 1'-Epi-Gemcitabine 3',5'-dibenzoate is an impurity of Gemcitabine, which is an anticancer drug. The impurity can be found in the methanolic fraction of the extract and it's an epimer of Gemcitabine. The pharmacopoeia for this compound are USP and EP. Custom synthesis and natural or synthetic are possible for this compound.Formule :C23H19F2N3O6Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :471.41 g/molRemdesivir impurity 1
CAS :Remdesivir impurity 1 is a drug product, analytical and Metabolism studies. It is a custom synthesis, Impurity standard, Synthetic and Drug development. Remdesivir impurity 1 is an API impurity that is a natural and has CAS No. 1355049-95-4. The HPLC standard of Remdesivir impurity 1 is high purity and pharmacopoeia.Formule :C12H13N5O4Degré de pureté :Min. 95%Masse moléculaire :291.26 g/mol2-Hydroxy-2,3-tetrahydrofuranyl entecavir
CAS :2-Hydroxy-2,3-tetrahydrofuranyl entecavir is a drug product that is an impurity standard for 2-hydroxy-2,3-dihydrofuranilide. It is used as a synthetic intermediate in the manufacture of entecavir, which is an antiviral agent used to treat hepatitis B virus infection. 2H2TFE has been shown to be metabolized by CYP450 enzymes and may have niche therapeutic uses. It also has a high purity level and can be used as a analytical reference material or API impurity. CAS No. 1984788-96-6
Formule :C12H15N5O4Degré de pureté :Min. 95%Masse moléculaire :293.28 g/molAcyclovir EP Impurity Q
Acyclovir EP Impurity Q is a drug product that is used as the impurity standard for Acyclovir EP. It is a natural metabolite of acyclovir and may be found in the urine of patients taking this drug. Acyclovir EP Impurity Q has shown to have antiviral activity against herpes simplex virus type 1 and type 2. The structure of this compound has been determined by nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry.Degré de pureté :Min. 95%a-Ribavirin (impurity B)
CAS :Produit contrôléRibavirin is an antiviral drug that inhibits the synthesis of RNA and DNA. It is used to treat human immunodeficiency virus (HIV) infection, hepatitis B, and influenza A. Ribavirin is a nucleoside analog that acts as an antimetabolite by inhibiting acid synthesis in the host cell and therefore blocking viral replication. Ribavirin has been shown to inhibit dna viruses like herpes simplex virus type 1 and 2, as well as RNA viruses like influenza A and respiratory syncytial virus. Ribavirin also binds to the ribonucleotide reductase enzyme, which is necessary for the production of deoxyribonucleotides from ribonucleotides during DNA synthesis, thereby interfering with DNA replication.Formule :C8H12N4O5Degré de pureté :Min. 95%Masse moléculaire :244.2 g/molMethyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-a-D-glucopyranoside
CAS :Methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-alpha-D-glucopyranoside is an impurity of Dapagliflozin.
Formule :C22H27ClO7Degré de pureté :Min. 95%Masse moléculaire :438.9 g/mol1'-Epi gemcitabine, hydrochloride
CAS :Gemcitabine hydrochloride is an analog of the natural nucleoside cytidine. It is a chemotherapeutic drug that is used in the treatment of pancreatic, lung and breast cancer. Gemcitabine hydrochloride is metabolized to its active form by deamination of cytosine residues in DNA. This conversion is catalyzed by the enzyme cytidine deaminase. Gemcitabine hydrochloride has been shown to be effective against metastatic pancreatic cancer and advanced-stage non-small cell lung cancer, as well as early-stage breast cancer. Gemcitabine hydrochloride has also been shown to be effective against certain types of lymphoma and leukemia.
Formule :C9H12ClF2N3O4Degré de pureté :Min. 95%Masse moléculaire :299.66 g/molEmpagliflozin tetraacetate
CAS :Empagliflozin tetraacetate is a drug product that has been manufactured by chemical synthesis. It is a white to off-white crystalline powder with a molecular weight of 597.7 and a purity of 98.2%. Empagliflozin tetraacetate has been formulated as the hydrochloride salt, which is soluble in water and alcohols. The USP/BP/EP specifications for this drug are 5% impurity standard, analytical, API impurity, Synthetic, Metabolism studies, niche, High purity>. This drug product can be used in research and development as well as for manufacturing pharmaceutical products. It is not intended for use in humans or animals.Formule :C27H29ClO10Degré de pureté :Min. 95%Masse moléculaire :548.97 g/molSofosbuvir impurity 2
CAS :Sofosbuvir impurity 2 is a synthetic compound that is used as an impurity standard for the HPLC assay of sofosbuvir. It is a white to off-white crystalline solid at room temperature.Formule :C22H29ClN3O9PDegré de pureté :Min. 95%Masse moléculaire :545.91 g/molCapecitabine 2',3'-cyclic carbonate
CAS :Capecitabine is a prodrug that is converted to 5-fluorouracil in the body. It has been used for many years in the treatment of breast cancer and colorectal cancer. Capecitabine 2',3'-cyclic carbonate is an analytical standard, research and development tool, high purity drug product, and impurity standard for HPLC analysis. This compound is also used as a pharmacopoeia reference material for quality control testing. Capecitabine 2',3'-cyclic carbonate can be custom synthesized or purified from natural or synthetic sources.Formule :C16H20FN3O7Degré de pureté :Min. 95%Masse moléculaire :385.34 g/molAcyclovir Impurity K
CAS :Acyclovir Impurity K is a drug product that is used as an analytical reference standard for metabolism studies. Acyclovir Impurity K is a natural product and an impurity of acyclovir, which has CAS No. 1797131-64-6. The chemical name of this drug is 3-hydroxy-2,5,6,7-tetrahydro-1H-[1]benzopyran-2,4(3H)-dione. It can be synthesized in the laboratory by custom synthesis or it can be obtained from a commercial supplier as an impurity standard. This product is used to help with drug development and research and development in the pharmaceutical industry. It can also be used as a high purity HPLC standard for pharmacopoeia testing purposes.
Formule :C17H22N10O6Degré de pureté :Min. 95%Masse moléculaire :462.42 g/molRemdesivir impurity 8
Remdesivir impurity 8 is a metabolite of remdesivir, a drug product that belongs to the class of synthetic compounds. Remdesivir impurity 8 has been used as a research and development standard for HPLC analysis. It is also used as an impurity standard in pharmacopoeia and drug development. This impurity has shown natural activity in metabolism studies, but it is not known if this activity is due to the compound itself or an artifact from its synthesis.
Formule :C30H39N6O8PDegré de pureté :Min. 95%Masse moléculaire :642.64 g/molAdefovir Dipivoxyl Impurity I
CAS :Adefovir Dipivoxyl Impurity I is a white crystalline powder with a melting point of 232–234 °C. It is soluble in water, and insoluble in organic solvents. Adefovir Dipivoxyl Impurity I is used as an impurity standard for Adefovir Dipivoxyl and has been shown to be metabolized by CYP3A4 and UGT1A9. This impurity also has the potential to inhibit DNA synthesis in cells.Formule :C21H34N5O9PDegré de pureté :Min. 95%Masse moléculaire :531.5 g/molValacyclovir Related Compound D
CAS :Valacyclovir Related Compound D is a synthetic metabolite of Valacyclovir. It is the primary metabolite of Valacyclovir, which has been shown to inhibit the activity of bacterial DNA polymerase. Valacyclovir Related Compound D is an impurity standard for valacyclovir and can be synthesized in quantities as per customer requirement.Formule :C15H24N6O4Degré de pureté :Min. 95%Masse moléculaire :352.39 g/mol2'-Deoxy-5,6-didehydro-2',2'-difluoro-6-hydroxyuridine
2'-Deoxy-5,6-didehydro-2',2'-difluoro-6-hydroxyuridine is an analytical standard that is used in research and development of drugs. This compound has been designated as an impurity in a drug product. It has also been used as a reference standard for HPLC analysis. 2'-Deoxy-5,6-didehydro-2',2'-difluoro-6-hydroxyuridine is a metabolite of the drug product. This compound is not found in nature and has been synthesized artificially.Formule :C9H12F2N2O6Degré de pureté :Min. 95%Masse moléculaire :282.2 g/mol5'-Epi lamivudine
CAS :Lamivudine epimerFormule :C8H11N3O3SDegré de pureté :Min. 95%Masse moléculaire :229.26 g/molRemdesivir impurity 11
CAS :CAS No. 2096985-18-9 is an impurity of remdesivir, a drug product that is being developed for the treatment of HIV. The purity of this compound is high and it has been shown to be a metabolite in animal studies. Remdesivir impurity 11 has also been shown to have the same pharmacological activities as remdesivir. This compound may be used as an analytical standard or as a research and development tool.
Formule :C21H23N6O8PDegré de pureté :Min. 95%Masse moléculaire :518.42 g/molSofosbuvir impurity 3
CAS :Sofosbuvir impurity 3 is a research and development, impurity standard, custom synthesis, drug product, synthetic, high purity, pharmacopoeia, drug development and analytical. Sofosbuvir impurity 3 is a metabolite of sofosbuvir which has been studied in metabolism studies using HPLC. This compound has also been shown to inhibit the growth of some bacteria.Formule :C22H29FN3O9PDegré de pureté :Min. 95%Masse moléculaire :529.45 g/mol3,9-Dihydro-9-[(2-hydroxyethoxy)methyl]-1H-Purine-2,6-dione
CAS :3,9-Dihydro-9-[(2-hydroxyethoxy)methyl]-1H-Purine-2,6-dione is an impurity found in the synthesis of a drug product. It is also used as an analytical standard for HPLC methods and as a pharmacopoeia standard. 3,9-Dihydro-9-[(2-hydroxyethoxy)methyl]-1H-Purine-2,6-dione has been shown to be produced by the metabolism of other drugs such as caffeine. This impurity is not expected to have any therapeutic effects when administered to humans.Formule :C8H10N4O4Degré de pureté :Min. 95%Masse moléculaire :226.19 g/mol4-Dehydroxy-4-dimethylhydroxysilyl entecavir
CAS :4-Dehydroxy-4-dimethylhydroxysilyl entecavir is an impurity standard for the drug product Entecavir. It is a synthetic drug that inhibits the production of human immunodeficiency virus (HIV) by binding to reverse transcriptase and blocking its activity. The metabolite of 4-dehydroxy-4-dimethylhydroxysilyl entecavir, entecavir, is also used as a treatment for HIV. Synthetic 4-dehydroxy-4-dimethylhydroxysilyl entecavir is used in clinical trials as a drug product and metabolite of entecavir to measure the concentration of the active ingredient in plasma and other body fluids. 4DDSILENT has been shown to have antiviral properties against HIV due to its ability to inhibit transcriptional activation by binding to reverse transcriptase, which prevents RNA from being synthesized into DNA.Formule :C14H21N5O3SiDegré de pureté :Min. 95%Masse moléculaire :335.43 g/molEntecavir (1S,3S,4S) diastereomer
CAS :Entecavir is a drug product that is custom synthesized to order. It has a purity of >98% and is made up of the 1S,3S,4S diastereomer. Entecavir is an antiviral drug that belongs to the nucleoside analog family and inhibits viral replication by inhibiting DNA polymerase α. The metabolism studies for entecavir have been completed and it was found that entecavir undergoes hydrolysis by esterases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Entecavir also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.Formule :C12H15N5O3Degré de pureté :Min. 95%Masse moléculaire :277.28 g/molRemsesivir related compound 11
CAS :Remsesivir related compound 11 is a research and development chemical that is used as an analytical, drug development, or impurity standard. It is a high purity, pure substance that can be custom synthesized or natural. Remsesivir related compound 11 has been shown to be metabolized by cytochrome p450 enzymes and glutathione reductase and has shown pharmacopoeia activities. Remsesivir related compound 11 can also be used as a HPLC standard for the detection of metabolites in pharmaceutical products.Formule :C15H23Cln04pDegré de pureté :Min. 95%Masse moléculaire :347.78 g/molTriphenylmethanol
CAS :Triphenylmethanol (TPM) is an inhibitor of the enzyme alcohol dehydrogenase. It is synthesized by reacting p-hydroxybenzoic acid with a hydroxyl group in the presence of trifluoroacetic acid and potassium carbonate. The reaction solution was then analyzed by x-ray crystallography, revealing the molecular structure of TPM. TPM binds to the metal ion in a hydroxyl group, preventing alcohol dehydrogenase from oxidizing ethanol to acetaldehyde. This mechanism also explains why TPM inhibits other enzymes that use this same metal ion cofactor such as carboxypeptidase A and aminopeptidase P, which are involved in protein synthesis and degradation.
Formule :C19H16ODegré de pureté :Min. 95%Couleur et forme :White Beige Slightly Yellow PowderMasse moléculaire :260.33 g/molRemdesivir impurity 4
CAS :Remdesivir is an antiviral drug that inhibits the viral enzyme, RNA-dependent RNA polymerase. Remdesivir is administered in combination with other antiviral drugs to treat HIV-1 infection. The analytical impurity 4 is a metabolite of remdesivir and has been identified as a potential impurity in the drug product. CAS No. 2096985-18-9 is the molecular weight of this impurity. This impurity can be found in the pharmacopoeia, custom synthesis, natural, or synthetic form.Formule :C21H27N2O7PDegré de pureté :Min. 95%Masse moléculaire :450.42 g/mol(S)-AMPA
CAS :(S)-AMPA is an active isomer of AMPA and a selective agonist of AMPA.Formule :C7H10N2O4Couleur et forme :SolidMasse moléculaire :186.17Sarcolysine hydrochloride
CAS :Sarcolysine hydrochloride, also known as Melphalan HCl, is a nitrogen mustard and alkylating agent that has been studied for use in multiple myeloma therapy.Formule :C13H19Cl3N2O2Couleur et forme :SolidMasse moléculaire :341.661-Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium
CAS :Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium (18:1 Lyso-PS) modulates macrophage G2A for neutrophil inflammation resolution.Formule :C24H45NNaO9PCouleur et forme :SolidMasse moléculaire :545.586Gemcitabine monophosphate
CAS :R306465, a potent HDAC1/8 inhibitor, has broad antitumor effects (IC50: 30-300 nM) on solid and blood cancers.Formule :C9H12F2N3O7PCouleur et forme :SolidMasse moléculaire :343.18Apadenoson
CAS :Apadenoson: potent A2 agonist, A3 inhibitor (IC 45 nM), anti-inflammatory, for neurological research.Formule :C23H30N6O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :486.52Adefovir diphosphate
CAS :Adefovir monophosphate: antiviral ANP active against HBV, herpes; ntRTI for hepatitis B, not HIV-1 effective.Formule :C8H13N5O7P2Couleur et forme :SolidMasse moléculaire :353.17Galidesivir triphosphate
CAS :Galidesivir triphosphate halts viral RNA replication by inhibiting RDRP and NS5B, and combats Ebola in mice; derived from prodrug Galidesivir.Formule :C11H18N5O12P3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :505.21Creatine monohydrate
CAS :Creatine monohydrate powers ATP for short, high-intensity activities in muscles and brain.Formule :C4H11N3O3Degré de pureté :99.87%Couleur et forme :White SolidMasse moléculaire :149.15(R)-Oxiracetam
CAS :(R)-Oxiracetam is the (R)-enantiomer of the nootropic drug oxiracetam. Oxiracetam is a nootropic drug of the racetam family and stimulant.Formule :C6H10N2O3Couleur et forme :SolidMasse moléculaire :158.16Diapocynin
CAS :Diapocynin (Dehydrodiacetovanillone), a dimer of Apocynin, acts as an orally administered inhibitor of NADPH oxidase.Formule :C18H18O6Couleur et forme :SolidMasse moléculaire :330.33CNV-2197944
CAS :CNV-2197944 is a novel, small molecule, state-dependent calcium channel blocker, designed to selectively inhibit highly active Cav2.2 channels.Formule :C19H20F3N3O3SCouleur et forme :SolidMasse moléculaire :427.44LY450108
CAS :LY450108 is a potentiator of the AMPA receptor that can be used in Parkinson's disease studies.Formule :C19H22F2N2O3SDegré de pureté :98.87% - 99.91%Couleur et forme :SolidMasse moléculaire :396.45S07-2010
CAS :S07-2010 is a pan-Aldo-Keto Reductase 1C3 (AKR1C3) inhibitor with potential anti-cancer activity, inducing apoptosis in A549/DDP cells.Formule :C19H21N3O3SDegré de pureté :98.13%Couleur et forme :SolidMasse moléculaire :371.45Molnupiravir
CAS :Molnupiravir (EIDD-2801) is an isopropyl ester prodrug of the ribonucleoside analog EIDD-1931 with oral bioavailability.Cost-effective and quality-assured.Formule :C13H19N3O7Degré de pureté :99.81% - 99.98%Couleur et forme :SolidMasse moléculaire :329.31Ref: TM-T60951
5mg38,00€10mg57,00€1mL*10mM (DMSO)63,00€25mg74,00€50mg113,00€100mg177,00€200mg334,00€500mg710,00€1g973,00€Emtricitabine impurity 17
CAS :Please enquire for more information about Emtricitabine impurity 17 including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C8H10FN3O4SDegré de pureté :Min. 95%Masse moléculaire :263.24 g/mol2'-Deoxy-2',2'-difluorouridine
CAS :Gemcitabine metaboliteFormule :C9H10F2N2O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :264.19 g/molHTS07545
CAS :HTS07545, an SQOR inhibitor (IC50: 30nM), slows H2S breakdown, researched for heart failure.
Formule :C22H18N2O3Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :358.39

