Nucléosides et Nucléotides
Les nucléosides sont des composés formés par une base azotée liée à un sucre (ribose ou désoxyribose). Lorsqu’un groupe phosphate est ajouté au nucléoside, un nucléotide est formé. Ces composés sont essentiels en biologie cellulaire, car les nucléotides sont les blocs fondamentaux de l’ADN et de l’ARN, responsables du stockage et de la transmission de l’information génétique. Les nucléosides ont des applications dans le traitement des maladies virales, en tant qu’inhibiteurs de la réplication virale. Les nucléotides, en plus de leur rôle structurel dans les acides nucléiques, interviennent dans les processus énergétiques, comme la synthèse de l’ATP.
Chez CymitQuimica, nous proposons une large gamme de nucléosides et de nucléotides essentiels à la recherche en biologie moléculaire, virologie et pharmacologie.
3420 produits trouvés pour "Nucléosides et Nucléotides"
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N6-(2-Phenylethyl)adenosine
CAS :<p>N6-(2-Phenylethyl)adenosine (N6-Phenethyladenosine) is an adenosine derivative and an agonist of adenosine receptors with Ki values of 11.8 nM and 30.1 nM for</p>Formule :C18H21N5O4Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :371.39S19-1035
<p>S19-1035: potent AKR1C3 inhibitor with 3.04 nM IC50, useful for tumor research.</p>Formule :C19H17ClN2O3Degré de pureté :99.98%Couleur et forme :SoildMasse moléculaire :356.80Emtricitabine impurity 17
CAS :<p>Please enquire for more information about Emtricitabine impurity 17 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C8H10FN3O4SDegré de pureté :Min. 95%Masse moléculaire :263.24 g/molMeropenem EP impurity A
CAS :<p>Meropenem EP impurity A is a heterocyclic nitro compound that is used to treat various infectious diseases. Meropenem EP impurity A is an inhibitor of the toll-like receptor, which is a protein that recognizes and binds to bacterial lipopolysaccharide and mediates inflammation. This drug may be effective in treating colorectal carcinoma, autoimmune diseases, chronic bronchitis, cancer, and other inflammatory diseases. Meropenem EP impurity A also has anti-cancer properties due to its structural similarity with the chemotherapeutic agent 5-fluorouracil. Meropenem EP impurity A inhibits the synthesis of proteins by binding to the aminoacyl-tRNA synthetase enzyme and blocking the production of proteins vital for cell division.</p>Formule :C17H27N3OS6Degré de pureté :95%NmrCouleur et forme :PowderMasse moléculaire :401.5 g/molPeldesine
CAS :<p>Peldesine (BCX 34), an oral purine nucleoside phosphorylase blocker, halts T-cell growth; used in CTCL, psoriasis, HIV research. IC50: 800 nM.</p>Formule :C12H11N5ODegré de pureté :99.27% - 99.9%Couleur et forme :SolidMasse moléculaire :241.252'-Deoxy-2',2'-difluorouridine
CAS :<p>Gemcitabine metabolite</p>Formule :C9H10F2N2O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :264.19 g/molAPX-115
CAS :<p>APX-115 (Ewha-18278) (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4).</p>Formule :C17H18ClN3ODegré de pureté :98.62%Couleur et forme :SolidMasse moléculaire :315.8Molnupiravir
CAS :<p>Molnupiravir (EIDD-2801) is an isopropyl ester prodrug of the ribonucleoside analog EIDD-1931 with oral bioavailability.Cost-effective and quality-assured.</p>Formule :C13H19N3O7Degré de pureté :99.81% - 99.98%Couleur et forme :SolidMasse moléculaire :329.31HTS07545
CAS :<p>HTS07545, an SQOR inhibitor (IC50: 30nM), slows H2S breakdown, researched for heart failure.</p>Formule :C22H18N2O3Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :358.396-Pterinyl folic acid
CAS :<p>6-Pterinyl folic acid is a chemical reagent that is used in the synthesis of pteridine derivatives. It is also used to prepare sulfates and esters of folic acid. 6-Pterinyl folic acid can be synthesized by reacting glutamic anhydride with trifluoroacetic acid and dimethylformamide. It reacts with sulfate ions to produce 6-pterinyl sulfate, which can then be hydrolyzed to release 6-pterinyl folic acid. The reagent can be used in the manufacture of fluoroquinolones, antibiotics that are used to treat a variety of bacterial infections including tuberculosis.</p>Formule :C26H24N12O7Degré de pureté :Min. 95%Masse moléculaire :616.55 g/molPSI 7976
CAS :<p>PSI 7976 is an analog of the nucleophilic attack drug, ribavirin. PSI 7976 inhibits the hepatitis C virus (HCV) replicon by inhibiting the function of the NS5B polymerase. In clinical studies, PSI 7976 has been shown to be active against HCV genotype 1 and 3. It has also been shown to inhibit replication of HIV-1 in vitro and to act synergistically with lamivudine against HIV-1 in human cells. PSI 7976 may be useful as a potential antiviral agent for treatment of other viral infections such as hepatitis B virus (HBV), herpes simplex virus type 2 (HSV-2), or cytomegalovirus (CMV).</p>Formule :C22H29FN3O9PDegré de pureté :Min. 95%Masse moléculaire :529.45 g/molPhox-I2
CAS :<p>Phox-I2 is an NOX2-specific inhibitor. Phox-I2 reverts ROS-accumulation and leads to refusion of mitochondrial networks.</p>Formule :C18H15N3O4Degré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :337.33Methyl 2-deoxy-D-ribopyranoside
CAS :<p>Methyl 2-deoxy-D-ribopyranoside (2DDR) is a natural compound that can be found as an impurity in some pharmaceuticals. The chemical structure of 2DDR is similar to 6-fluoro-3-indoxyl beta-D-galactopyranoside, which is used to treat tuberculosis. The metabolism of 2DDR has been studied, and it has been found that this metabolite is excreted in the urine unchanged or conjugated with glucuronic acid. This product can be used for drug development and research and development. It can also be used as an impurity standard for HPLC analysis or as a custom synthesis for niche applications.</p>Formule :C6H12O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :148.16 g/molDapagliflozin Impurity 26
CAS :<p>Dapagliflozin Impurity 26 is an impurity that is found in the chemical analysis of Dapagliflozin. It is a metabolite, which is not present in the drug product and does not have any biological activity. Dapagliflozin Impurity 26 has been shown to be a high purity, analytical standard for HPLC and can be used as an API impurity for drug development. This compound can also be synthesized by natural or synthetic means.</p>Degré de pureté :Min. 95%Zidovudine diphosphate
CAS :<p>Zidovudine diphosphate, an NRTI antiretroviral, treats HIV/AIDS by blocking reverse transcriptase, preventing viral DNA synthesis.</p>Formule :C10H15N5O10P2Couleur et forme :SolidMasse moléculaire :427.2ML-090
CAS :<p>ML-090 is NOX1-specific inhibitor(IC50 = 90 nM) which is >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50s >10 μM).</p>Formule :C14H10N4Degré de pureté :98.55%Couleur et forme :SolidMasse moléculaire :234.26AMPA receptor modulator-2
CAS :<p>AMPA receptor modulator-2 is a modulator of AMPA receptor. The pIC50 value for TARPγ2 dependent AMPA receptor is 10.1.</p>Formule :C15H6F6N4OSDegré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :404.29ES 936
CAS :<p>ES 936 is a potent and selective NQO1 inhibitor, inhibiting more than 95% of NQO1 100 nM, with a cell line-dependent inhibition duration.</p>Formule :C18H16N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :356.33GLX481304
CAS :<p>GLX481304 is a selective Nox-2 and Nox-4 inhibitor, exhibiting IC50 values of 1.25 μM.</p>Formule :C23H29N7OCouleur et forme :SolidMasse moléculaire :419.52Carbovir
CAS :<p>Carbovir, an NRTI, induces mitochondrial toxicity in human liver cancer cells.</p>Formule :C11H13N5O2Couleur et forme :SolidMasse moléculaire :247.25Emtricitabine triphosphate tetrasodium salt
CAS :<p>Emtricitabine triphosphate tetrasodium salt is the tetrasodium salt form of the phosphorylated anabolite (-)-Emtricitabine triphosphate, an active nucleoside</p>Formule :C8H9FN3Na4O12P3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :575.11Ganciclovir triphosphate
CAS :<p>Ganciclovir triphosphate: synthetic 2'-deoxy-guanosine analog, treats/prevents CMV, IC50 of 0.01 μM, effective across species.</p>Formule :C9H16N5O13P3Couleur et forme :SolidMasse moléculaire :495.17Galidesivir dihydrochloride
CAS :<p>Galidesivir inhibits RdRP; has broad antiviral effects on various RNA viruses; effective against Ebola, Marburg in animals.</p>Formule :C11H17Cl2N5O3Couleur et forme :SolidMasse moléculaire :338.19Brivudine monophosphate
CAS :<p>Brivudine monophosphate, a phosphate ester, inhibits DNA repair, induces apoptosis, and may downregulate STAT3 and chemoresistance genes.</p>Formule :C11H14BrN2O8PCouleur et forme :SolidMasse moléculaire :413.12NOX2-IN-2
CAS :<p>NOX2-IN-2 (compound 33) is a potent inhibitor of NOX2, disrupting the p47phox-p22phox protein-protein interaction with a dissociation constant (K i) of 0.24 μM.</p>Formule :C25H25N7O3Couleur et forme :SolidMasse moléculaire :471.51Sorivudine
CAS :<p>Sorivudine (BV-araU) is an antiviral blocking DNA synthesis in viruses like varicella, HSV-1, and Epstein-Barr.</p>Formule :C11H13BrN2O6Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :349.13GS 441524 triphosphate
CAS :<p>Triphosphorylated form of an antiviral nucleoside analog with activity against zoonotic feline infectious peritonitis virus (FIPV) and severe acute respiratory syndrome (SARS) virus from Coronaviridae family. The compound is the biologically active form of the GS 441524 prodrug and being triphosphorylated, it competes with natural nucleoside triphosphates in cells and interferes with viral RNA synthesis. Made to order.</p>Formule :C12H12N5O13P3·4NaDegré de pureté :(31P-Nmr) Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :531.20 g/molEmtricitabine triphosphate
CAS :<p>Emtricitabine triphosphate is an active metabolite of Emtricitabine, a drug for HIV/HBV that inhibits reverse transcriptase.</p>Formule :C8H13FN3O12P3SCouleur et forme :SolidMasse moléculaire :487.19Lobucavir
CAS :<p>Lobucavir (BMS-180194; SQ 34514) is a nucleoside analogue and an antiviral agent with broad-spectrum activity against various viruses, including HBV, HIV/AIDS, and α, β, and γ herpesviruses (including CMV, herpes simplex virus, varicella-zoster virus, and Epstein-Barr virus).</p>Formule :C11H15N5O3Couleur et forme :SolidMasse moléculaire :265.27Galidesivir
CAS :<p>Galidesivir (BCX4430) is an antiviral compound that inhibits viral RNA-dependent RNA polymerase (RdRp) activity and reduces lung infections in infected animals.</p>Formule :C11H15N5O3Degré de pureté :96.73% - 99.13%Couleur et forme :SolidMasse moléculaire :265.27
