Peptides et Protéines
Les peptides sont de courtes chaînes d'acides aminés reliées par des liaisons peptidiques, tandis que les protéines sont des chaînes d'acides aminés plus longues et complexes pouvant adopter des structures tridimensionnelles fonctionnelles. Ces deux types de composés sont essentiels à diverses fonctions biologiques, comme la catalyse des réactions (enzymes), la défense immunitaire (anticorps) et la signalisation cellulaire. Les protéines ont une structure hiérarchique comprenant la séquence d’acides aminés, ainsi que les structures secondaire, tertiaire et quaternaire. Les peptides sont utilisés dans les thérapies pharmaceutiques et cosmétiques pour leurs propriétés biologiques spécifiques, notamment dans le traitement des maladies métaboliques ou l’amélioration de la régénération cellulaire. Les protéines, quant à elles, ont des applications en biotechnologie, en nutrition et en médecine régénérative.
Chez CymitQuimica, nous proposons des peptides et des protéines de haute pureté pour la recherche en biotechnologie et les applications thérapeutiques.
3160 produits trouvés pour "Peptides et Protéines"
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Teriparatide-d10
CAS :Produit contrôléFormule :C181D10H281N55O51S2Couleur et forme :NeatMasse moléculaire :4127.72Dodecyl Polyoxyethylene (23) Aldehyde
CAS :Produit contrôlé<p>Applications Polyoxyethylene (23) Lauric Acid is an intermediate in the synthesis of Bril L-23 Proline (LIFETC1), a polyethylene glycol derivative of Proline (P755995), an amino acid and precursor (with vitamin C) for collagen, the building block of the structure of tendons, ligaments, arteries, veins and muscles.<br>References Bondarenko, L.B., et al.: Int. J. Peptides., 2, 1687 (2012); Rimer, T., et al.: Biomacromolecules, 13, 2110 (2012);<br></p>Formule :C14H28O2(C2H4O)nCouleur et forme :Neat(S,S)-Hydroperoxy Des(boric Acid) Bortezomib
CAS :Produit contrôlé<p>Impurity Bortezomib USP Impurity L<br>Stability Unstable in Methanol<br>Applications (R)-Hydroperoxy Des(boric Acid) Bortezomib is an impurity of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer.<br>References Nawrocki, S.T., et al: Cancer Research, 65, 11510 (2005); Drahl C.: Chem. and Eng. News, 87, 41 (2009);<br></p>Formule :C19H24N4O4Couleur et forme :White To Off-WhiteMasse moléculaire :372.42(S)-Hydroperoxy Des(boric Acid) Bortezomib
CAS :Produit contrôlé<p>Applications (S,S)-Hydroperoxy Des(boric Acid) Bortezomib is an impurity of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer.<br>References Nawrocki, S.T., et al: Cancer Research, 65, 11510 (2005); Drahl C.: Chem. and Eng. News, 87, 41 (2009);<br></p>Formule :C19H24N4O4Couleur et forme :NeatMasse moléculaire :372.42Daptomycin Impurity B1-I
<p>Applications Daptomycin Impurity B1-1 is an impurity of Daptomycin (D193350), cyclic lipopeptide antibiotic derived from a fermentation product of Streptomyces roseosporus; disrupts plasma membrane function in gram-positive bacteria. Antibacterial.<br>References Allen, N.E., et al.: Antimicrob. Agents Chemother., 31, 1093 (1987), Tully, F.P., et al.: Expert Opin. Invest. Drugs, 8, 1223 (1999),<br></p>Formule :C44H66N10O15•(C2HF3O2)Couleur et forme :Off White SolidMasse moléculaire :975.0511402N(1-(3-Methylbutanamido) N(1-Des(boric Acid)) Bortezomib
CAS :Produit contrôlé<p>Applications N(1-(3-Methylbutanamido) N(1-Des(boric Acid)) Bortezomib is an impurity of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer.<br>References Nawrocki, S.T., et al: Cancer Research, 65, 11510 (2005); Drahl C.: Chem. and Eng. News, 87, 41 (2009);<br></p>Formule :C19H22N4O3Couleur et forme :White To Off-WhiteMasse moléculaire :354.403(2S)-1-Nitrosopyrrolidine-2-carboxamide
CAS :Produit contrôléFormule :C5H9N3O2Couleur et forme :NeatMasse moléculaire :143.14(D-His2)-Leuprolide Trifluoroacetic Acid Salt
CAS :Produit contrôlé<p>Impurity Leuprolide Acetate EP Impurity B TFA salt<br>Applications Synthetic nonapeptide agonist analog of LH-RH. Antineoplastic (hormonal).<br>References Vilchez-Martinez, J.A., et al.: Biochem. Biophys. Res. Commun., 59, 1226 (1974), Sennello, L.T., et al.: J. Pharm. Sci., et al.: 75, 158 (1986), Wheeler, J.M., et al.: Am.J. Obstet. Gynecol., 167, 1367 (1992), Eri, L.M., et al.: J. Urol., 150, 359 (1993),<br></p>Formule :C59H84N16O12·x(C2HF3O2)Couleur et forme :NeatMasse moléculaire :1209.398Lysipressin Acetic Acid Salt
CAS :<p>Applications Lysipressin Acetic Acid Salt, is an analog of Vasopressin (A769550), a powerful vasopressor used to modulate blood pressure. An endogenous antidiuretic hormone in most mammalian species. It is released into the blood from nerve terminals in the posterior pituitary and median eminence. It is a neurotransmitter in the central nervous system and also implicated in a variety of physiological processes such as regulating water balance by antidiuretic action.<br>References Yamashita, K. et al.: Mol. Phylo., 67, 520 (2013); Hua F. et al.: J. Emerg. Med., 44, 434 (2013); Perucca, J. et al.: J. AM. Soc. Nephrol., 19, 1721 (2008); Toba, K. et al.: Prog. Brain Res., 119, 337 (1998); Berrada, K. et al.: J. Biol. Chem., 275, 27229 (2000);<br></p>Formule :C46H65N13O12S2·xC2H4O2Couleur et forme :White SolidMasse moléculaire :1056.23 + (60.05)xCyclosporin AM 4N
CAS :Produit contrôléFormule :C61H109N11O12Couleur et forme :NeatMasse moléculaire :1188.58Trofinetide (>90%)
CAS :Produit contrôlé<p>Applications Trofinetide is a synthetic analogue of the endogenous N-terminus tripeptide, Glycine-Proline-Glutamate (GPE), that has shown to be neuroprotective in animal models of brain injury.<br>References Wei, H.H. et al.: J Neuroinflammation. 2009 Aug 5;6:19.<br></p>Formule :C13H21N3O6Degré de pureté :>90%Couleur et forme :NeatMasse moléculaire :315.32Linear Daptomycin Hydrochloride Salt
CAS :<p>Applications Linear Daptomycin Hydrochloride Salt is the hydrochloride salt of L466470, which is the open-conformation of Daptomycin (D193350), cyclic lipopeptide antibiotic derived from a fermentation product of Streptomyces roseosporus; disrupts plasma membrane function in gram-positive bacteria. Antibacterial. Daptomycin Impurity<br>References Allen, N.E., et al.: Antimicrob. Agents Chemother., 31, 1093 (1987), Tully, F.P., et al.: Expert Opin. Invest. Drugs, 8, 1223 (1999),<br></p>Formule :C72H103N17O27·x(ClH)Degré de pureté :~80%Couleur et forme :NeatMasse moléculaire :1638.69 + x(36.46)(alphaR)-(1S,2S,3R,5S)-Pinanediol-1-amino-3-methylbutane-1-boronate Trifluoroacetic Acid Salt
CAS :Produit contrôlé<p>Applications Bortezomib (B675700) intermediate. A boronic acid dipeptide derivative as proteasome inhibitors.<br>References Kisselev, A., et al.: Chem. Biol., 8, 739 (2001), Kisselev, A., et al.: J. Biol. Chem., 278, 35869 (2003), Verdoes, M., et al.: Chem. Biol., 13, 1217 (2006),<br></p>Formule :C15H28BNO2·C2HF3O2Couleur et forme :NeatMasse moléculaire :379.22N-(1-Carboxy-3-phenylpropyl)-S-lisinopril (Mixture of diastereomers)
CAS :Produit contrôlé<p>Applications N-(1-Carboxy-3-phenylpropyl)-S-lisinopril (Mixture of diastereomers) is an impurity of lisinopril (L468985), an orally active angiotensin-converting enzyme (ACE) inhibitor.<br>References Shinde, V., et. al.: J. Pharm. Biomed. Anal., 43, 381 (2007); Goa, K.L., et al.: Drugs, 52, 564 (1996), Chaturvedi, N., et al.: Lancet, 351, 28 (1998)<br></p>Formule :C31H41N3O7Couleur et forme :NeatMasse moléculaire :567.672-((4S,7S,10S,13S,15R)-10-Benzyl-15-hydroxy-7,13-diisobutyl-15-methyl-1-morpholino-2,5,8,11,14,18-hexaoxo-4-phenethyl-17-oxa-3,6,9,12-tetraazanonadecan-19-yl)-2-hydroxysuccinic Acid
<p>Applications 2-((4S,7S,10S,13S,15R)-10-Benzyl-15-hydroxy-7,13-diisobutyl-15-methyl-1-morpholino-2,5,8,11,14,18-hexaoxo-4-phenethyl-17-oxa-3,6,9,12-tetraazanonadecan-19-yl)-2-hydroxysuccinic Acid is an impurity of Carfilzomib (C183460), which is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.<br>References Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);<br></p>Formule :C46H65N5O14Couleur et forme :White To Off-WhiteMasse moléculaire :912.033Lopinavir Metabolite M-3/M-4
CAS :Produit contrôlé<p>Applications A major metabolite of Lopinavir (L469480) . It is a COVID19-related research product.<br>References Molla, A., et al.: J. Virology, 250, 255 (1998), Sham, H., et al.: Antimicrob. Agents Chemother., 42, 3218 (1998), Kumar, G., et al.: Drug Metab. Dispos., 27, 86 (1999),<br></p>Formule :C37H48N4O6Couleur et forme :NeatMasse moléculaire :644.805-Oxo-L-proline-d5
CAS :Produit contrôlé<p>Applications 5-Oxo-L-proline-d5 is a labelled cyclized derivative of L-Glutamic Acid (G596960). The pyroglutamate core has potential application for synthesis of novel anti-bacterials.<br>References Mischo A. et al.: ChemBioChem., 13, 1421 (2012); Angelov P. et al.: Org. Biomol. Chem.: 10, 3472 (2012);<br></p>Formule :C52H5H2NO3Couleur et forme :White To Off-WhiteMasse moléculaire :134.14(AlphaS)-3-[2-(2,6-Dimethylphenoxy)acetyl]-N-[(1S,3S,4S)-4-[[2-(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide
CAS :Produit contrôlé<p>Impurity Lopinavir EP Impurity R<br>Applications (αS)-3-[2-(2,6-Dimethylphenoxy)acetyl]-N-[(1S,3S,4S)-4-[[2-(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide (Lopinavir EP Impurity R) is an impurity of Lopinavir (L469480), a selective HIV protease inhibitor.<br>References Chitturi, S.R., et al.: J. Pharma. Biomed. Anal., 48, 1430 (2008); Devi, A.S.L., et al.: Magnet. Reson. Chem., 45, 424 (2007);<br></p>Formule :C47H58N4O7Couleur et forme :NeatMasse moléculaire :791.0(alphaS)-α-Amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]-benzenepropanamide Monohydrochloride
CAS :Produit contrôlé<p>Applications (αS)-α-Amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]-benzenepropanamide Monohydrochloride is a Bortezomib (B675700) intermediate which is used in the evaluation of bone-targeted proteasome inhibitors for myeloma.<br>References Agyin, J.K., et al.: Bioorg. Med. Chem. Lett., 23, 6455 (2013); Traenckner, E., et al.: EMBO. J., 13, 5433 (1994)<br></p>Formule :C24H37BN2O3·ClHCouleur et forme :NeatMasse moléculaire :448.8341Boceprevir-d9
CAS :Produit contrôlé<p>Applications A labelled NS3 serine protease inhibitor of hepatitis C virus. It is a COVID19-related research product.<br>References Malcolm, B., et al.: Antimicrob. Agents Chemother., 50, 1013 (2006); Cubero, M., et al.: Virology, 370, 237 (2008); Venkatraman, S., et al.: J. Med. Chem., 49, 6074 (2006);<br></p>Formule :C272H9H36N5O5Couleur et forme :NeatMasse moléculaire :528.73
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