Sels et Dérivés d’API
Les sels des Ingrédients Pharmaceutiques Actifs (API) sont des composés formés par la réaction d’un acide avec une base, aboutissant à un équilibre ionique. Ces sels améliorent souvent la solubilité et la stabilité des API, facilitant ainsi leur absorption par l’organisme. Les dérivés des API sont des variantes chimiques d’un principe actif qui peuvent présenter des propriétés améliorées ou modifiées afin d’optimiser leur efficacité thérapeutique. Les sels d’API sont utilisés dans la formulation de médicaments oraux, injectables et topiques. De plus, les dérivés d’API peuvent améliorer la pharmacocinétique des médicaments, notamment en permettant une libération contrôlée des substances actives.
Chez CymitQuimica, nous proposons des sels et dérivés d’API avec la pureté et la qualité requises pour la recherche et le développement de formulations pharmaceutiques.
79473 produits trouvés pour "Sels et Dérivés d’API"
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5,6-trans Travoprost
CAS :<p>Applications An 5,6-trans isomeric impurity of the selective FP prostaglandin receptor agonist Travoprost (T715600).<br></p>Formule :C26H35F3O6Couleur et forme :NeatMasse moléculaire :500.552-(3-Cyano-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic Acid Ethyl Ester
CAS :<p>Applications 2-(3-Cyano-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic Acid Ethyl Ester, can be used for the synthesis of Febuxostat (F229000), an antipodagrics.<br>References Zheng, F., et al.: Zhongguo Yiyao Gongye Zazhi, 40, 726 (2009);<br></p>Formule :C14H12N2O3SCouleur et forme :NeatMasse moléculaire :288.32Decarbonyl Rivaroxaban
CAS :<p>Applications Decarbonyl Rivaroxaban is an impurity of Rivaroxaban (R538000), which is a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.<br>References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),<br></p>Formule :C18H20ClN3O4SCouleur et forme :White To Off-WhiteMasse moléculaire :409.8915-Keto Travoprost
CAS :Produit contrôlé<p>Stability Light Sensitive<br>Applications An impurity of the selective FP prostaglandin receptor agonist Travoprost (T715600) used as an ocularly applied intraocular pressure reducing agent.<br></p>Formule :C26H33F3O6Couleur et forme :NeatMasse moléculaire :498.533-(4H-1,2,4-Triazol-4-yl)-1H-pyrazole-4-carboxamide
CAS :Produit contrôlé<p>Impurity Allopurinol EP Impurity C / Allopurinol USP Related Compound C<br>Applications 3-(4H-1,2,4-Triazol-4-yl)-1H-pyrazole-4-carboxamide (Allopurinol EP Impurity C) is an impurity of Allopurinol (A547300).<br></p>Formule :C6H6N6OCouleur et forme :Off-WhiteMasse moléculaire :178.15Ivermectin B1a (>85%)
CAS :Produit contrôlé<p>Applications Ivermectin B1a is a major component of Ivermectin (I940800), a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). An invitro inhibitor of SARS-CoV-2/ Covid-19.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chabala, J.C., et al.: J. Med. Chem., 23, 1134 (1980); Campbell, W.C., et al.: Science, 221, 823 (1983); Bennett, J.L., et al.: Parasitol. Today, 4, 226 (1988); Plaisier, A.P., et al.: J. Infect. Dis., 172, 204 (1995);; Caly, L., et al.: Antivir. Res., 178<br></p>Formule :C48H74O14Degré de pureté :>85%Couleur et forme :NeatMasse moléculaire :875.092-[2-[[4-[(5S)-5-[[[(5-Chloro-2-thienyl)carbonyl]amino]methyl]-2-oxo-3-oxazolidinyl]phenyl]amino]ethoxy]-acetic Acid Hydrochloride
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications 2-[2-[[4-[(5S)-5-[[[(5-chloro-2-thienyl)carbonyl]amino]methyl]-2-oxo-3-oxazolidinyl]phenyl]amino]ethoxy]-acetic Acid Hydrochloride is a metabolite of Rivaroxaban (R538000) which is a novel antithrombotic agent. Rivaroxaban is also a highly potent and selective, direct FXa inhibitor.<br>References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005)<br></p>Formule :C19H20ClN3O6S·HClCouleur et forme :White Light RedMasse moléculaire :453.9036462-[3-(Aminocarbonyl)-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic Acid
CAS :Produit contrôlé<p>Applications 2-[3-(Aminocarbonyl)-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic acid is an impurity of Febuxostat (F229000), an xanthine oxidase/xanthine dehydrogenase inhibitor used for the treatment of hyperuricemia and chronic gout.<br>References Kadivar, M.H., et al.: J. Pharma. Biomed. Anal., 56, 749 (2011);<br></p>Formule :C16H18N2O4SCouleur et forme :White To Off-WhiteMasse moléculaire :334.39Keto Diclofenac Sodium Salt
CAS :<p>Applications Keto Diclofenac Sodium Salt is an impurity of Diclofenac (D436450), a known nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor.<br>References Sun, S., et al.: J. Liq. Chroma., 17, 433 (1994); Kenny, J. R., et al.: J. Med. Chem., 47, 2816 (2004); Sasaki, A., et al.: J. Pharmacol. Sci., 108, 266 (2008); Dalvie, D., et al.: Chem. Res. Toxicol., 22, 357 (2009);<br></p>Formule :C14H8Cl2NO3·NaCouleur et forme :NeatMasse moléculaire :332.112-Oxo-ivabradine Hydrochloride
CAS :Produit contrôléFormule :C27H34N2O6·ClHCouleur et forme :NeatMasse moléculaire :519.034-[4-[(5S)-5-Phthalimidomethyl-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone
CAS :Produit contrôléFormule :C22H19N3O6Couleur et forme :NeatMasse moléculaire :421.405-Desisobutyl,5-(2-Methyl-prop-1-en-1-yl) Butalbital
CAS :Produit contrôlé<p>Applications 5-(2-Methyl-1-propen-1-yl)-5-(2-propen-1-yl)-2,4,6(1H,3H,5H)-pyrimidinetrione is a potential impurity of Butalbital (B690100), a controlled substance (depressant). Sedative, hypnotic.<br>References Inaba, T., et al.: Clin. Pharmacol. Ther., 18, 558 (1975), Fritch, D., et al.: J. Anal. Toxicol., 33, 569 (2009), Wille, S., et al.: Ther. Drug Monit., 31, 511 (2009),<br></p>Formule :C11H14N2O3Couleur et forme :NeatMasse moléculaire :222.241-Chloroethyl Cyclohexyl Carbonate
CAS :<p>Applications 1-Chloroethyl Cyclohexyl Carbonate is a genotoxic impurity used in the synthesis of Candesartan Cilexetil. an angiotensin II receptor antagonist.<br>References Kakasaheb, N. et al.: Int. J. Pharm. Sci., 6, 370 (2014); Mao, Y. et al.: Heterocycles, 81, 1503 (2010);<br></p>Formule :C9H15ClO3Couleur et forme :NeatMasse moléculaire :206.67Diclofenac Ethyl Ester
CAS :Produit contrôlé<p>Impurity Aceclofenac EP Impurity C<br>Applications A Diclofenac derivative as anti-inflammatory and analgesic agent. Aceclofenac EP Impurity C<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dannhardt, G., et al.: Eur. J. Med. Chem., 36, 109 (2001), Sorbera, L., et al.: Drug Future, 26, 133 (2001), Sorbera, L., et al.: Drug Future, 26, 133 (2001),<br></p>Formule :C16H15Cl2NO2Couleur et forme :White To Light BrownMasse moléculaire :324.202-Chloroethylamine Hydrochloride
CAS :Produit contrôlé<p>Applications 2-Chloroethylamine Hydrochloride is used as a reagent in the synthesis of 6-desfluoroquinolones as potential anti-HIV drugs. Also used as a reagent in the synthesis of ellipticine derivatives as anticancer agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sancineto, L., et al.: Bioorg. Med. Chem., 22, 4658 (2014); Mori, R., et al.: Eur. J. Med. Chem., 82, 16 (2014)<br></p>Formule :C2H6ClN·ClHCouleur et forme :NeatMasse moléculaire :115.992-Amino-5-(trifluoromethoxy)phenyl Thiocyanate
CAS :<p>Applications An impurity of Riluzole (R510000).<br></p>Formule :C8H5F3N2OSCouleur et forme :NeatMasse moléculaire :234.20Ramipril Methyl Ester(>85%)
CAS :<p>Applications Ramipril Methyl Ester is an impurity of Ramipril (R111000). Ramipril Impurity A.<br>References Eckert, H., et al.: Arzneim.-Forsch./Drug Res., 35, 1251 (1985), Aboul-Enein, H., et al.: Anal. Lett., 24, 2217 (1991), Bonazzi, D., et al.: J. Pharm. Biomed. Anal., 16, 431 (1997),<br></p>Formule :C22H30N2O5Degré de pureté :>85%Couleur et forme :NeatMasse moléculaire :402.48N,N’-Bis[Des(5-chloro-2-carvoxythienyl) Rivaroxaban] Urea
CAS :Produit contrôléFormule :C29H32N6O9Couleur et forme :WhiteMasse moléculaire :608.60N-Nitroso Propafenone (2,2,3,3,3-Propyl-D5)
Produit contrôléFormule :C21D5H21N2O4Couleur et forme :NeatMasse moléculaire :375.473Ticagrelor Acetonide
CAS :<p>Stability Hygroscopic<br>Applications 2-[[(3aS,4R,6S,6aa)-4-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-2,2-dimethyl-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-6-yl]oxy]ethanol is an intermediate in the synthesis of Ticagrelor (T437700) which is an anticoagulant.<br>References Qiao, D., et al.: Preparation of anticoagulant Ticagrelor, China Patent 104592237, May 6, 2015;<br></p>Formule :C26H32F2N6O4SCouleur et forme :NeatMasse moléculaire :562.63Deferasirox Methyl Ester
CAS :Produit contrôlé<p>Applications Deferasirox Methyl Ester is a derivative of Deferasirox (D228650); an orally active tridentate iron chelator.<br>References Hershko, C., et al.: Blood, 97, 1115 (2001); Galanello, R., et al.: J. Clin. Pharmacol., 43, 565 (2003); Nick, H., et al.: Curr. Med. Chem., 10, 1065 (2003)<br></p>Formule :C22H17N3O4Couleur et forme :White To BeigeMasse moléculaire :387.394-(4-Nitrophenyl)-3-morpholinone
CAS :Produit contrôléFormule :C10H10N2O4Couleur et forme :NeatMasse moléculaire :222.20(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (2R)-Hydroxy(phenyl)ethanoate
CAS :<p>Applications (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine is an intermediate in the preparation of orally active reversible P2Y12 receptor antagonists such as Ticagrelor (T437700)for the prevention of thrombosis.<br>References Springthorpe, B. et al.: Bioorg. Med. Chem. Lett., 17, 6013 (2007);<br></p>Formule :C9H9F2N·C8H8O3Couleur et forme :NeatMasse moléculaire :321.32Cyclosporin C
CAS :Produit contrôlé<p>Applications A group of nonpolar cyclic oligopeptides with immunosupppressant activity.<br>References van Wartburg, A., et al.: Prog. Med. Chem., 25, 1 (1988), Jorgensen, K.A., et al.: Scand. J. Imunol., 57, 93 (2003), Vollenbroeker, et al.: Transplant. Proc., 37, 1741 (2005),<br></p>Formule :C62H111N11O13Degré de pureté :>80%Couleur et forme :NeatMasse moléculaire :1218.614-(Trifluoromethyl)aniline
CAS :Produit contrôlé<p>Impurity Leflunomide EP Impurity A; Leflunomide USP Related Compound A<br>Applications 4-(Trifluoromethyl)aniline (Leflunomide EP Impurity A; Leflunomide USP Related Compound A) is a 4-Substituted aniline derivatives exert special hematotoxicity on the red blood cells and induce leukocytosis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Weber, W., et al.: Pharmacol. Rev., 37, 25 (1985), Hein, D., et al.: Carcinogenesis, 14, 1633 (1993), Payton, M., et al.: Microbiology, 147, 1137 (2001), Mushtaq, A., et al.: J. Biol. Chem., 277, 12175 (2002),<br></p>Formule :C7H6F3NCouleur et forme :NeatMasse moléculaire :161.125-Desmethyl-3-methyl Leflunomide
CAS :Produit contrôlé<p>Impurity Leflunomide EP Impurity E<br>Applications 5-Desmethyl-3-methyl Leflunomide (Leflunomide EP Impurity E) is the 3-methyl-isomer of Leflunomide (L322750), as a poisonous impurity.<br></p>Formule :C12H9F3N2O2Couleur et forme :NeatMasse moléculaire :270.214-Hydrazinobenzoic Acid
CAS :Produit contrôlé<p>Applications 4-Hydrazinobenzoic Acid, is an organic building block used for the synthesis of various chemical and pharmaceutical compounds. It can be used for the synthesis of Deferasirox (D228650), an orally active tridentate iron chelator.<br>References Ying, Ch., et al.: Xiandai Yaowu Yu Linchuang, 27, 446 (2012); Galanello, R., et al.: J. Clin. Pharmacol., 43, 565 (2003), Nick, H., et al.: Curr. Med. Chem., 10, 1065 (2003);<br></p>Formule :C7H8N2O2Couleur et forme :NeatMasse moléculaire :152.15Cyclophosphamide USP Related compound D
CAS :Formule :C7H18ClN2O4P(HCl)Masse moléculaire :260.7 : 2(36.46)Cefepime Dihydrochloride Monohydrate
CAS :Formule :C19H24N6O5S2(HCl)H2OMasse moléculaire :480.56 : 2(36.46) : 18.02
![2-[2-[[4-[(5S)-5-[[[(5-Chloro-2-thienyl)carbonyl]amino]methyl]-2-oxo-3-oxazolidinyl]phenyl]amino]e…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FC421840.webp&w=3840&q=75)
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