Sulfamides et Dérivés

Applications Phthalide may be used in scaffolds for the design of high potency monoamine oxidase (MAO) inhibitors.
References Li, P.Z., et. al.: Med. Chem. Res., 23, 3624 (2014)

Applications N-Methyl(p-tosyl)carbamic Acid Methyl Ester is a methyl ester derivative of N-[(arylsulfonyl)methyl]carbamates that display intramolecular shielding.
References Van der Werf, S. et al.: Rec. Trav. Chim. Pays-Bas, 89, 423 (1970);

Applications 3-Methoxy Acetaminophen-d3 is deuterium labeled 3-Methoxy Acetaminophen (M226050). 3-Methoxy Acetaminophen is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).
References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)

Stability Hygroscopic, Moisture Sensitive
Applications 1-​[1-​(4-​Chlorobenzoyl)​-​5-​hydroxy-​2-​methyl-​1H-​indole-​3-​acetate]β-​D-​Glucopyranuronic Acid is an analog of Indomethacin Acyl-β-D-glucuronide a metabolite of Indomethacin (I641000). Acyl glucuronides have been implicated in the toxicity of many xenobiotics and marketed drugs.
References Abid, A., et al.: Biochem. Pharmacol., 50, 557 (1995), Gamage, N., et al.: Toxicol. Sci., 90, 5 (2006), Cerveny, L., et al.: Drug Metab. Dispos., 35, 1032 (2007), Hayeshi, R., et al.: Eur. J. Pharm. Sci., 35, 383 (2008),

Applications Ethyl Chlorthalidone is an impurity of Chlorthalidone (C427500). Chlorthalidone is used as a diuretic; an antihypertensive.
References Beisenherz, et al.: Arch. Int. Pharmacodyn. Ther., 161, 76 (1966), Zsoter, et al.: J. Pharmacol. Exp. Ther., 180, 723 (1972), Singer, J.M., et al.: Anal. Profiles Drug Subs., 14, 1 (1985),

Applications The major hydroxylated metabolite of Gliclazide (G409875).
References Miyazaki, H., et al.: Eur. J. Drug Metab. Pharmacokinet., 8, 117 (1983), Rieutord, A., et al.: Xenobiotica, 25, 1345 (1995),

Applications Intermediate in the preparation of Indomethacin
References Kalgutkar, A.S., et al.: Bioorg. Med. Chem., 13, 6810 (2005),

Applications BIS(4-NITROPHENYL) SULFONE (cas# 1156-50-9) is a useful research chemical.

Applications Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2 (COX-2). Etodolac displays anti-inflammatory effects in both adjuvant arthritic and normal rats. Etodolac is an anti-inflammatory; analgesic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Humber, L.G., et al.: Med. Res. Rev., 7, 1 (1987); Balfour, J.A, et al.: Drugs, 42, 274 (1991); Kato, et al.: J. Pharm. Pharmacol., 53 1679 (2001);

Stability Hygroscopic
Applications Mefenamic acid metabolite.
References Besunder, J., et al.: Clin. Pharmacokinet., 14, 261 (1988), Smith, P., et al.: Drug Metab. Dipos., 18, 639 (1990), Kraus, D., et al.: Clin. Pharmacol. Ther., 54, 351 (1993), Sato, J., et al.: Biol. Pharm. Bull., 16, 811 (1993),