Monosaccharides

<p>N-acetyl D-glucosamine (GlcNAc) is an aldohexose (2-acetamido-2-deoxyglucose) in which the hydroxyl group at position 2 is replaced by NHAc (Collins, 2006). N-acetyl D-glucosamine forms the exoskeletons of molluscs and insects as the building block of the polysaccharide chitin (Rudrapatnam, 2003). N-acetyl D-glucosamine is a key component of N- and O-linked glycans, present in glycolipids and the glycosaminoglycan hyaluronic acid (Fallacara, 2018). A recent study has suggested that N-acetyl D-glucosamine may have therapeutic potential for COVID-19 as it affects the spike protein-ACE2 receptor interaction during the infection with SARS-CoV-2 virus (Baysal, 2021).</p>

<p>Glucal is a carbohydrate that is used as a synthon in organic synthesis. It has been shown to be anomeric and can be synthesized by acetylation of the corresponding aldose, or by the glycosidic bond reaction with borohydride reduction. Glucal is not stable at high pH and can undergo ring-opening reactions with nucleophiles such as sodium borohydride. Glucal also reacts with glycoconjugates to form new molecules, which are called glycosidic products.</p>

<p>Methyl β-D-maltopyranoside is a disaccharide that is an aglycon of maltosides. It has been shown to bind to the active site of alpha-d-glucopyranosidases, which are enzymes that hydrolyze alpha-d-glucopyranosides. Methyl β-D-maltopyranoside has also been shown to interact with dihedral angles and hydroxyl groups in the enzyme binding region, which may be due to conformational changes in the enzyme's active site. The kinetic constants for methyl β-D-maltopyranoside have been calculated by using an algorithm.</p>

<p>D-Glucose-13C6 is a complex carbohydrate, which is composed of a glucose molecule with one carbon atom labeled as C6. It is used to study the structure of carbohydrates and their interactions with proteins. D-Glucose-13C6 also has applications in the study of diseases such as Alzheimer's disease, Parkinson's disease, diabetes mellitus type 2, and cancer. In addition, this molecule can be used to measure plasma glucose concentrations in humans or animals. D-Glucose-13C6 is not active against bacteria such as Pseudomonas aeruginosa or Escherichia coli. The synthesis of D-glucose-13C6 requires anhydrous dextrose and unlabeled glucose.</p>

<p>Building block for polymers synthesis, ionic liquids and chiral auxiliaries</p>

<p>Phenyl-beta-D-thioglucuronic acid is a drug that is used to treat inflammatory diseases and autoimmune diseases. It is a basic structure that has been shown to have anti-estrogenic effects in vitro, although the mechanism of action is not well understood. Phenyl-beta-D-thioglucuronic acid can be crosslinked with proteins to form a matrix for wound healing. This drug has also been shown to be a potent inhibitor of proteases, and may inhibit other enzymes such as matrix metalloproteinases and serine proteases.</p>

<p>3-O-benzyl-diacetonide-d-glucose is a synthetic monosaccharide that can be used as a building block for oligosaccharides and polysaccharides. It is custom synthesized to meet your specific needs and can be modified with fluorination, methylation, or glycosylation. 3-O-benzyl-diacetonide-d-glucose has been shown to have high purity and is available in small quantities for custom synthesis.</p>

<p>4,6-O-Benzylidene-D-glucose is a potent inhibitor of the enzyme dibutyltin oxide, which is involved in the synthesis of energy. It has been shown to have clinical activity in rat cardiomyocytes and has been tested in clinical studies. 4,6-O-Benzylidene-D-glucose inhibits enzymes by forming hydrogen bonds with their substrates. This compound also interacts with hydrochloric acid to form a stable complex that prevents it from interacting with other molecules. 4,6-O-Benzylidene-D-glucose is rapidly broken down into glucose and benzaldehyde when it reacts with carbonyl groups or amines. The asymmetric synthesis of this compound can be achieved using an intramolecular hydrogen transfer reaction. <br>4,6-O-Benzylidene glucose is derived from D-mannose derivatives and contains a hydroxyl group on the central carbon</p>

<p>Canagliflozin is an oral diabetes drug that belongs to the class of sodium-glucose cotransporter 2 (SGLT2) inhibitors. It works by blocking reabsorption of glucose in the kidney, thereby lowering blood sugar levels. Canagliflozin has been shown to be a potent inhibitor of insulin resistance and has been used clinically in combination with metformin hydrochloride. The chemical stability of canagliflozin is dependent on its particle size, which can range from 10 micrometres to 100 micrometres. A number of analytical methods have been developed for canagliflozin, including high performance liquid chromatography with ultraviolet detection, gas chromatography with mass spectrometry detection, and dihedral angle analysis. Canagliflozin is an example of a polymorphic compound: it exists as two enantiomers due to chiral symmetry.</p>

<p>D-ido-Heptono-1,4-lactone is a glycosylation product of heptose with d-ido-D-glucofuranose and is a synthetic sugar. It has an Oligosaccharide, sugar, Synthetic, Fluorination, Custom synthesis, Methylation, Monosaccharide, Polysaccharide, saccharide Click modification. It has CAS No., Modification.</p>

<p>6-Deoxy-L-talose is a sugar that is found in the cell walls of bacteria. It is a component of glycan, which are long chains of sugar molecules linked together. Glycans are important for the structural integrity and function of bacterial cell walls. 6-Deoxy-L-talose is a monosaccharide that has been detected in the type strain of Bacillus subtilis and in wild-type strains of Pseudomonas aeruginosa. This sugar can be chemically analyzed using gas chromatography and mass spectrometry to determine its structure and chemical composition. 6-Deoxy-L-talose can be used to detect specific monoclonal antibodies against it, which could be useful for detecting bacterial infections or determining how antibiotics affect bacteria.</p>

<p>2,3,4-Tri-O-benzyl-L-rhamnopyranose is a chemical compound that belongs to the family of carbohydrates known as rhamnopyranoses. It is a derivative of L-rhamnose, which is a naturally occurring aldohexose sugar. The compound is often used as a glycosyl donor in the synthesis of oligosaccharides and glycoconjugates. The three benzyl groups in the molecule provide protection for the hydroxyl groups, allowing for selective deprotection and glycosylation. 2,3,4-Tri-O-benzyl-L-rhamnopyranose is also used as a precursor in the synthesis of various natural products.</p>

<p>Blue dextran is a high molecular weight (MW 2000000) polymer that has been used as a model compound in experimental studies of transport and control. It is an oxidant, which can be used to make hydroquinone in the presence of other chemicals. Blue dextran has also been used to study the environment, for mathematical modeling and chromatographic experiments. This polymer has been shown to have antimicrobial activity against some microorganisms. Experiments with blue dextran have shown that it can inhibit the growth of Lactobacillus acidophilus and other bacteria.</p>

<p>L-Daunosamine hydrochloride is a fluorinated sugar that is synthesized in the laboratory. It has been used for the modification of polysaccharides and other saccharides. L-Daunosamine hydrochloride is a monosaccharide that can be found in several complex carbohydrates. The CAS number for this chemical is 19196-51-1. This chemical has a high purity level, which makes it valuable for use as a synthetic material.</p>

<p>Inositol is a member of the B-vitamin family and is classified as a sugar alcohol. It has a structural similarity to glucose and can be synthesized by plants, bacteria, and mammals. Inositol is found in high concentrations in the brain and liver. Inositol has been shown to inhibit guanine nucleotide-binding proteins (G proteins) and ryanodine receptor channels in HL-60 cells. It also inhibits cancer cell proliferation and suppresses ovarian activity. Inositol appears to work by binding to the inositol-1,4,5-trisphosphate receptor on the surface of cells, thereby inhibiting intracellular calcium release from its storage site within the endoplasmic reticulum. The effects of inositol are mediated by dinucleotide phosphate or p-nitrophenyl phosphate.</p>

<p>Sophoricoside is a natural compound present in the fructus of Sophora flavescens and is used as an anti-diabetic medicine. It has been shown to have genotoxic effects, which may be due to its ability to induce reactive oxygen species (ROS) and DNA damage. Sophoricoside also has a matrix effect on radiation. This effect has been shown in rat cardiac cells and human serum. Sophoricoside also exhibits hepatoprotective properties by reducing hepatic steatosis, which may be due to its ability to inhibit lipogenesis and stimulate fat oxidation. In addition, sophoricoside has been shown to have anti-inflammatory activities.</p>

<p>1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-D-glucopyranose is a small molecule that binds to the D1 protein of the glycolytic enzyme phosphofructokinase and inhibits enzymatic activity. This inhibitor is used in diagnostic procedures to identify mutations in the gene encoding for this protein, which is associated with familial and sporadic aneurysms. The inhibitor is also used to study the pathogenic mechanism of aneurysms. 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy--D--glucopyranose has been shown to inhibit cell nuclei polymerase in vitro and prevents cell division in vivo.</p>

<p>1,2,3,4-Tetra-O-benzyl-a-D-mannopyranoside is an active drug that belongs to the group of thyromimetics. It is a prodrug that is hydrolyzed in vivo to 1,2,3,4-tetra-O-acetyl-a-D-mannopyranose. This drug has been shown to be effective in treating nervous system diseases such as sclerosis and endogenous disease. The acetylation of the benzyl group on this molecule prevents it from being metabolized by enzymes that are found in the liver. The unmodified form of this drug is rapidly absorbed into the blood and reaches high concentrations quickly.</p>

<p>Donor for Koenigs-Knorr type galactosylation and other anomeric substitutions</p>

<p>2,3,4,6-Tetra-O-benzyl-D-galactopyranose is a building block which can be used as both a galactosyl donor and acceptor in the synthesis of saccharides. The benzyl protecting groups can be readily and selectively cleaved but are stable to a variety of reaction conditions allowing chemical manipulations to be carried out on the rest of the saccharide. 2,3,4,6-Tetra-O-benzyl-D-galactopyranose has been used in the synthesis of potential cholera toxin inhibitors, analogues of α-galactosyl ceramide (iNKT agonist) and more recently in the synthesis of Scleropentaside A.</p>