Monosaccharides

<p>1-Deoxy-D-fructose is a sugar that is found in plants. It has been shown to stimulate insulin release from the pancreas and regulate glucose levels. 1-Deoxy-D-fructose has been used as a pharmaceutical preparation for the treatment of diabetes mellitus. 1-Deoxy-D-fructose is not metabolized by cells, but is taken up by cells and reacts with reactive oxygen species (ROS) to produce hydrogen peroxide. This reaction may be responsible for the biological effects of 1-deoxy-d-fructose.</p>

<p>2-Acetamido-2-deoxy-D-galacturonamide is a potential drug candidate that exhibits potent activity against gram-negative bacteria. It has been shown to exhibit structural similarity to the antigen in the outer membrane of bacteria, and is an amide with a potential use as a protein glycosylation inhibitor. 2-Acetamido-2-deoxy-D-galacturonamide has been shown to be effective against P. aeruginosa, which is a major cause of hospital acquired infections. This drug candidate inhibits the synthesis of proteins by interfering with the biosynthesis of peptidoglycan, which is an essential component of the bacterial cell wall and outer membrane. 2-Acetamido-2-deoxy-D-galacturonamide also can be used for detection sensitivity testing and identification of bacterial strains by hydrogen fluoride treatment or expressed recombinant proteins.</p>

<p>Taxol is a natural product that is isolated from the bark of the Pacific Yew tree. It has been found to have antitumor activity against human and murine sarcoma, as well as human cancer cell lines. Taxol has been shown to inhibit the growth of cancer cells by binding to the β-subunit of tubulin, preventing polymerization into microtubules and therefore affecting mitosis. Taxol also inhibits glucose uptake and utilization by cancer cells, which may in part account for its anti-tumor activity. Taxol also contains galloyl groups that are responsible for its antifungal activity.</p>

<p>(1S) -1- [(2S, 3R,4R) -N-Benzyl-3- benzyloxy- 4-hydroxymethyl-1- azetidinyl] -1, 2- ethanediol is a water soluble, white to off-white powder that can be used as a synthetic carbohydrate. It has the CAS number of 112065-78-8 and can be custom synthesized for specific modifications. The purity of this product is high and it is methylated and glycosylated. This product can be used in click chemistry to make other compounds.</p>

<p>3,4,6-Tri-O-acetyl-2-deoxy-2-fluoro-D-glucopyranosyl fluoride is a fluorine containing compound. It has been analyzed using spectroscopic techniques and found to be a white crystalline solid with an empirical formula of C12H14F3O11.</p>

<p>3,4:5,6-Di-O-Isopropylidene-L-idonic acid methyl ester (DIPIM) is a synthetic carbohydrate that is used in the modification of saccharides and oligosaccharides. DIPIM is a fluorinated monosaccharide that can be synthesized by the click chemistry reaction. It is highly pure, with a purity level of 99.9%. DIPIM has been shown to react with glycosyl acceptors to form glycosyl derivatives. This compound also has potential in the design of new therapeutic agents for cancer treatment.</p>

<p>Methyl 2,3-di-O-benzyl-a-D-galactopyranoside is a fluorination reagent that can be used to introduce fluorine atoms in the sugar backbone of a carbohydrate. It has been used for the synthesis of complex carbohydrates and oligosaccharides. Methyl 2,3-di-O-benzyl-a-D-galactopyranoside can also be used to modify glycosylation or polysaccharide structures by methylating or chlorinating the sugar moiety. The chemical is available from various suppliers at different purity levels.</p>

<p>Specific and potent inhibitor of lysosomal α-galactosidase with IC50 in nanomolar range. It acts as pharmacological chaperone and assists folding of the wild type and mutant versions of the enzyme. It places itself in the instable active site and prevents the damage to the enzyme during the passage through Golgi apparatus, endoplasmatic reticulum and lysosome axis. The exposure to this compound leads to increased levels of functional α-galactosidase in models for lysosomal storage disorders and brings therapeutic benefits to patients with Fabry disease.</p>

<p>1,2:5,6-Di-O-isopropylidene-D-mannitol is an organic compound that belongs to the group of mesoporous materials. It has a high surface area and is capable of absorbing large amounts of water. 1,2:5,6-Di-O-isopropylidene-D-mannitol has been shown to be able to absorb chloride ions in acidic environments due to its acidic hydrolysis properties. The water that is absorbed by this material can then be released when the solution becomes neutral again. This material can also act as a proton sponge and may have applications in the treatment of acid mine drainage or other industrial pollution. 1,2:5,6-Di-O-isopropylidene-D-mannitol may be used for chromatography techniques such as gas chromatography and liquid chromatography due to its functional groups that are sensitive to changes in pH levels.</p>

<p>3-Deoxy-D-glucose (3DG) is a molecule that belongs to the class of carbohydrates. It is an analog of D-glucose, which is the key substrate for the production of energy in mammalian cells. 3DG has been shown to inhibit the uptake of glucose by trypanosomes and also inhibits glycolysis in mammalian cells. The inhibition of glycolysis may be due to its ability to prevent the phosphorylation of glucose by hexokinase, thus blocking the conversion of glucose into glucose 6-phosphate. 3DG is biosynthesized from d-xylose, which is a five carbon sugar that can be oxidized to form CO2 and H2O.</p>

<p>1,2-ene-glucose is a methylated glucose that can be custom synthesized. It has been modified with a click modification and fluorination. It is an Oligosaccharide and Polysaccharide that is used as a Carbohydrate in the synthesis of complex carbohydrates. The purity of 1,2-ene-glucose is high and it can be modified with Monosaccharides or sugar.</p>

<p>This compound is a custom synthesis, modification and fluorination of an acetylated glycoside. It is a methylated monosaccharide with a saccharide at the reducing end. This product can be used in the synthesis of oligosaccharides, glycosylation and sugar modifications. The CAS number for this compound is 58907-27-3.</p>

<p>D-[UL-13C6]Galacturonic acid potassium salt is a fatty acid that is used as a feedstock in the production of monoclonal antibodies. The 13C isotope provides information on the structure and function of proteins, such as enzyme activities and covalent linkages. D-[UL-13C6]Galacturonic acid potassium salt has been shown to inhibit the growth of bacteria and can be used for the treatment of infectious diseases. D-[UL-13C6]Galacturonic acid potassium salt binds to bacterial cell surfaces by interacting with hydroxyl groups on lipopolysaccharides, which are found on the outer membrane of Gram-negative bacteria, preventing their replication and inhibiting their ability to form biofilms. D-[UL-13C6]Galacturonic acid potassium salt has also been shown to be effective against hyperproliferative disease cells, such as prostate cancer cells.</p>

<p>Methyl 2,3,4-tri-O-pivaloyl-6-O-triisopropylsilyl-a-D-mannopyranoside is a custom synthesis of an oligosaccharide with high purity. It is a complex carbohydrate that has been modified to have fluorination. The modification of the saccharide was done by Click chemistry, which is a type of radical reaction. Methyl 2,3,4-tri-O-pivaloyl-6-O-triisopropylsilyl-a-D-mannopyranoside is a monosaccharides and sugar that has been synthesized.</p>

<p>2,3:4,6-Di-O-cyclohexylidene-a-D-mannopyranose is a custom synthesis product. It can be modified with fluorination, methylation or monosaccharide substitution. The synthesis of 2,3:4,6-Di-O-cyclohexylidene-a-D-mannopyranose involves an oxidative coupling of glycerol and acetone to the corresponding 1,1,2,2 tetraacetate. The latter is then converted to the desired product by means of an acid catalyzed cyclization reaction. This compound is also synthetically derived from the sugar mannose via a series of reactions including methylation and glycosylation.</p>

<p>A protected glucofuranose.</p>

<p>Methyl 2,3,4-tri-O-pivaloyl-6-O-trityl-a-D-glucopyranoside is a custom synthesis of an oligosaccharide. The sugar is attached to the glycosylation site of the peptidoglycan cell wall of bacteria. This modification prevents bacterial growth by interfering with the cell wall biosynthesis that is required for protein synthesis and cell division.</p>

<p>5-O-Carbomethoxy-1,2-O-isopropylidene-3-O-p-toluenesulfonyl-a-D-xylofuranose is a synthetic chemical that is used in antiperspirant and deodorant products. It works by inhibiting the activity of the eccrine glands and causing a temporary blockage of sweat release. This chemical also decreases the production of bacteria on the skin surface, which can cause bad odors. 5OCMPTOSF is a combination product that includes both an antiperspirant and a deodorant.br&gt;<br>br&gt;<br>Antiperspirants are substances applied to the skin to prevent sweating. They work by blocking sweat from reaching the skin's surface or by masking body odor with their own fragrance. Antiperspirants are most effective when applied to dry skin and can be combined with other cosmetics such as moisturizers or sunscreens</p>

<p>Allyl 3-O-benzyl-2-O-chloroacetyl-a-L-rhamnopyranoside is a carbohydrate that belongs to the group of modified saccharides. It is a synthetic monosaccharide that can be used in the synthesis of complex carbohydrates and oligosaccharides. The fluorination at C1 position gives this compound high water solubility and improved stability. CAS No. 943307-50-4, Custom synthesis, High purity, Methylation, Glycosylation, Click modification.</p>

<p>4-Methoxyphenyl 6-O-tert-butyldimethylsilyl-2-deoxy-2-(2,2,2-trichloroethoxyformamido)-b-D-glucopyranoside is a synthetic oligosaccharide that is used as an intermediate in the synthesis of glycosylation products. This product can be custom synthesized and is provided with high purity. The CAS number for this product is 56874-06-1.</p>