Monosaccharides

1,2,3,4-Tetra-O-acetyl-6-deoxy-6-fluoro-a-D-glucopyranose is a synthetic sugar that contains four acetyl groups and one fluorine atom. It can be used for the synthesis of oligosaccharides and glycosylations. This product is custom synthesized according to customers' requirements, with high purity and good quality.

Glucose pentaacetate is a form of glucose that reacts with boron trifluoride etherate to produce anomers. This process can be used to synthesize the anomeric form of glucose, which is important for the biosynthesis of glycosides. Glucose pentaacetate has been shown to react with nitrate and trifluoride, forming conjugates with aluminum and chloride. The catalytic stereocontrol of this reaction allows for the production of disaccharides without hydrogen chloride or formylation.

(2R,3R,4S,5R,6S)-3,4,5-Trihydroxy-2-hydroxymethyl-7,9-diaza-1-oxa-spiro[4,5]decane-10-one-8-thione is a custom synthesis of a polysaccharide. It has been modified to include fluorination and methylation. The monosaccharides present are glucose and galactose. This polysaccharide also has a saccharide linkage to an oligosaccharide that contains glycosylation sites for sugar groups.

L-Daunosamine-b-methylglycoside hydrochloride is a high purity, custom synthesis of an oligosaccharide. This product is synthesized from D-mannose and L-daunosamine. The synthetic process begins with the click modification of the carbohydrate to introduce a methyl group onto the sugar. The resulting product is then glycosylated, fluorinated, and methylated to create the final product. L-Daunosamine-b-methylglycoside hydrochloride has been shown to act as a competitive inhibitor of bacterial dna gyrase, which helps maintain the integrity of bacterial DNA by preventing supercoiling. L-Daunosamine-b-methylglycoside hydrochloride has also been shown to inhibit protein synthesis in bacteria by binding to ribosomes, which are responsible for translating mRNA into proteins.

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Glcnacβ(1-3)GalNAc-α-Thr is a polysaccharide that is found in the human body, which is a complex carbohydrate. It is an oligosaccharide modification of galactose and alpha-threonine. Glcnacβ(1-3)GalNAc-α-Thr can be custom synthesized to order with high purity and monosaccharide content. This product is used for research purposes and has not been approved for therapeutic use. The CAS number for this compound is 286959-52-2.

Psicose diacetonide is a synthetic, custom-synthesized carbohydrate. It is a complex carbohydrate that is made of saccharides and has been modified to have a fluorinated monosaccharide. Psicose diacetonide is an oligosaccharide with a high purity and has been methylated and glycosylated.

D-Xylonic acid lithium salt is a redox potential regulator that belongs to the class of nucleotide phosphate. It has been shown to inhibit the transcriptional regulation of genes in Saccharomyces cerevisiae strain. D-Xylonic acid lithium salt inhibits the growth of bacteria by binding to a hydroxyl group on the surface of bacterial cells, which disrupts the cell membrane and causes cell death. This drug also has film-forming properties and can be used as a model system for studying glycolaldehyde, an intermediate in sugar metabolism.

O-(A-D-Galactopyranosyl)-D-galactose is a sugar that is used in the synthesis of complex carbohydrates. O-(A-D-Galactopyranosyl)-D-galactose can be fluorinated and methylated to produce o-(A-D-Galactopyranosyl)-2,6-dideoxy--glucose. This sugar has been shown to inhibit the growth of bacteria such as Mycobacterium tuberculosis and Mycobacterium avium complex. Synthesis of this sugar is done through a custom synthesis process with high purity and quality.

Nicotine-N-b-D-glucuronide hydrate is a metabolite of nicotine that is excreted in the urine as an organic anion. It has been shown to have anticancer activity against a variety of human cancer cell lines, including lung, stomach, colon, and prostate. Nicotine-N-b-D-glucuronide hydrate has also been shown to inhibit protein synthesis in vitro by interfering with the ability of cells to import amino acids such as tryptophan and phenylalanine. The same study also showed that this metabolite can cause symptoms similar to those caused by nicotine withdrawal.

O-topolin-9-glucoside is a custom synthesis of a sugar. It can be modified with fluorination, methylation, and click modification. O-topolin-9-glucoside is an oligosaccharide sugar that can be glycosylated or polysaccharided.

4-Epi-daunosamine is a glycopeptide antibiotic that is used to treat infections caused by Gram-positive bacteria. It binds to the cell wall of these bacteria and inhibits the synthesis of new cell walls. This causes the cells to burst and die, which leads to bacterial death. 4-Epi-daunosamine has been shown to be effective against animal pathogens such as Streptococcus pneumoniae, Haemophilus influenzae, and Clostridium perfringens. 4-Epi-daunosamine also has a low level of toxicity in humans, but can cause adverse effects such as nausea and vomiting if taken in large doses.

Nefopam is a compound that has been used as an analgesic and antipyretic. It is structurally related to the benzodiazepine class of drugs, but is not chemically equivalent to any other known drug. Nefopam has a low therapeutic index and can cause severe toxic effects in overdose. The most common adverse effects of nefopam are dizziness, drowsiness, headache, nausea and vomiting. An overdose can lead to death by respiratory paralysis or cardiac arrest.

Isosorbide is a naturally occurring sugar alcohol (polyol) that is found in small quantities in many plants and fruits. It is used as a pharmaceutical drug to treat angina pectoris, congestive heart failure, and high blood pressure. Isosorbide has been shown to inhibit the activity of matrix metalloproteinases (MMPs), which are enzymes that degrade extracellular matrix proteins. This effect may be beneficial for patients with disorders such as arthritis. Isosorbide also increases nitric oxide production, leading to vasodilation and improved blood flow. The therapeutic effect of isosorbide has been demonstrated in experimental models using mice with congestive heart failure due to myocardial infarction or chronic heart disease. Pharmacological treatment of these animals with isosorbide resulted in an improvement of left ventricular function, reduction of myocardial fibrosis, and reduced levels of cardiac markers.

Glufosfamide is a cytotoxic drug that is used in the treatment of some types of cancer. It is a prodrug that requires conversion to its active form, glufosfamid, by esterase enzymes before it can exert its genotoxic effects. Glufosfamide has shown to be active against platinum-resistant ovarian cancer and solid tumours. This drug also has been shown to inhibit the growth of prostate cancer cells and miapaca-2 cells, which are derived from pancreatic cancer. Glufosfamide has been found to have low toxicity in mice, but there may be adverse reactions when combined with other drugs such as erythromycin or ketoconazole.

Cis-Zeatin-9-glucoside is a plant hormone known as a cytokinin, which is primarily synthesized in plants such as Zea mays (corn) and other monocots. Cytokinins play a critical role in regulating plant growth and development by promoting cell division, influencing nutrient allocation, and delaying leaf senescence. The mode of action of cis-Zeatin-9-glucoside involves its role as a signaling molecule that interacts with specific receptors in plant cells, thereby triggering a cascade of gene expression changes that modulate physiological processes.

3-O-Triisopropylsilyl-D-glucal is a modified carbohydrate, which is a saccharide that has been modified by the addition of three isopropyl groups. This modification can be used to synthesize oligosaccharides and polysaccharides in order to obtain desired properties. 3-O-Triisopropylsilyl-D-glucal can also be used as a fluorinating agent in synthesis reactions. The compound is also custom synthesized and can be synthesized with high purity (>98%) or with methylation or glycosylation. 3-O-Triisopropylsilyl-D-glucal will react with nucleophiles like amines and alcohols to form adducts, which are then hydrolyzed to release the product.

3-Deoxy-3-fluoro-D-mannose (3DFM) is a synthetic sugar molecule that acts as an inhibitor of bacterial growth. It binds to the 6-phosphate group of nucleic acids, which prevents the addition of sugar molecules to ribose or deoxyribose groups. 3DFM also inhibits the synthesis of proteins and RNA, which are necessary for bacterial growth. 3DFM is a structural analog of mannose and glucose, and has been shown to be effective against chronic infections caused by bacteria that produce lectins, such as C. difficile. This drug can be used in combination with other antibiotics to enhance their effectiveness.