APIs pour la recherche et les impuretés

6-O-Desmethyl moxonidine is a drug product that is a metabolite of the parent compound, moxonidine. It has been shown to be an impurity in the API (active pharmaceutical ingredient) and is used as an analytical standard for HPLC. 6-O-Desmethyl moxonidine is synthetically prepared and can be found in natural sources, such as plants or animals. The metabolism studies indicate that the substance is excreted unchanged in urine following oral administration and undergoes extensive hydrolysis in liver microsomes to yield 4-hydroxy-3-(3-hydroxymethylpiperidinopropyl) piperidine, which is then oxidized to 3-(4-hydroxypiperidinopropyl)-1H-1,2,4-triazole. This product may cause skin irritation.

Glipizide EP Impurity F is a synthetic impurity that is used as a research and development impurity standard. It has high purity and is pharmacopoeia grade. Glipizide EP Impurity F is also a metabolite of the drug product Glipizide and has been shown to have analytical applications for pharmacokinetic studies. It can be synthesized from natural materials or can be custom synthesized depending on the needs of the customer.

Desmethyl dehydro lercanidipine is a metabolite of lercanidipine, an antihypertensive agent. Lercanidipine is a dihydropyridine calcium channel blocker that inhibits the influx of calcium ions into cardiac muscle cells and vascular smooth muscle cells. The desmethyl form of lercanidipine has been shown to have anti-inflammatory effects in rats with experimental arthritis. It has also been shown to inhibit the production of inflammatory cytokines in lipopolysaccharide-stimulated human peripheral blood mononuclear cells.

1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-b enzimidazole is an impurity of a drug product. It is a metabolite that has been shown to be present in human plasma and urine. This compound is synthetically produced and is not found in nature. It has been shown to have niche applications in both analytical chemistry and pharmacopoeia.

Please enquire for more information about 3’-o-Desmethyl aliskiren hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

1-(2-Furoyl)piperazine is a potent inhibitor of tyrosinase, an enzyme involved in the production of melanin. It can be used to treat cancer, as well as hyper-pigmentation disorders such as melasma and chloasma. 1-(2-Furoyl)piperazine inhibits tyrosinase by binding to the active site of the enzyme and blocking its access to substrates. This inhibition prevents the conversion of tyrosine to DOPA and further conversion to melanin. 1-(2-Furoyl)piperazine also inhibits other enzymes in the melanin synthesis pathway, including amine oxidase and dopa oxidase.

3'-[3-(3-Azido-2,3-dideoxy-b-D-erythro-pentofuranosyl)-3,6-dihydro-5-methyl-2,6-dioxo-1(2H)-pyrimidinyl]-3'-deoxythymidine is an analytical standard used in the R&D and drug development of 3'-azido derivatives of thymidine. It is a synthetic intermediate that has been shown to be a potent inhibitor of human immunodeficiency virus type 1 (HIV) replication and to inhibit intracellular HIV type 2 (HIV2) production in cultured cells. 3'-[3-(3-Azido-2,3,-dideoxy--b erythro--pentofuranosyl)-3,6--dihydro--5--methyl--2,6--dioxo--1(2H)--pyrimidinyl]-

N9-Des(4-acetoxy-3-(acetoxymethyl)but-1-yl) N7-[4-acetoxy-3-(acetoxymethyl)but-1-yl] famciclovir is an analytical standard that is used for drug development and as an impurity in the production of famciclovir. It has a purity of 99.0% and a melting point of 176°C. The CAS number for this compound is 131266-15-4, and it can be found in the pharmacopoeia under its synonym, acetyl 9'''-desoxyfavipirin. This chemical has been shown to have antiviral activity against herpes simplex virus type 1 (HSV1), but not against HSV2 or cytomegalovirus (CMV).

Enantiomer of Perindopril t-Butylamine

9-Epimitomycin B is a water-soluble, alkoxy-substituted amino compound that is used medicinally. It has antibacterial activity and has been shown to be effective against Gram-positive bacteria such as Staphylococcus aureus, Streptococcus pyogenes, and Enterococcus faecalis. 9-Epimitomycin B inhibits the growth of these bacteria by binding to their ribosomes and inhibiting protein synthesis. The carbon atoms in 9-epimitomycin B are linked to an alkoxy group at one end, which causes it to have a higher affinity for bacterial ribosomes than human ribosomes. 9-Epimitomycin B also binds to mitomycin C, which may be responsible for its antimetabolite properties.

Ros 234 is a dioxalate salt of rosiglitazone, and is an anti-cancer agent that inhibits the growth of cancer cells. Ros 234 has been shown to inhibit inflammatory conditions such as asthma, rheumatoid arthritis, and colitis. It also modulates immune and autoimmune responses.

Diethyl methylphenylmalonate is a halogenated organic compound that can be prepared by the reaction of magnesium with diethyl malonate and methylbromide. Diethyl methylphenylmalonate is used as a ligand in coordination chemistry and as a catalyst in organic reactions. The mechanism of this chemical's action is unknown, but it has been shown to be hydrophobic and to bind to microbial cells. It also has been demonstrated to have an oxidation catalyst activity. Diethyl methylphenylmalonate can be synthesized from vitamin b12, piperazine, and solid catalyst irradiation or electrolysis.

Ethyl 6-[4-[(5-chloro-1-oxopentyl)amino]phenyl]-4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-carboxylate is a chemical compound with various applications. It is soluble in methanol and has been found to interact with peptidoglycan, cellulose, and other substances. This compound has shown potential anticoagulation properties and has been studied for its effects on blonanserin, etoricoxib, 27-hydroxycholesterol, tenofovir, proton, famotidine, dimethyl fumarate, calpain, dimethyl sulfoxide, and reactive agents. Further research is needed to fully understand the potential applications of this compound and its interactions with different substances.

Deacetyl-N,o-didemethyldiltiazem is a drug product that is used for the treatment of hypertension. It is a synthetic compound and has not been found in nature. The impurity standard for this product is an analytical chemical that can be used to identify the presence of impurities in a sample. Deacetyl-N,o-didemethyldiltiazem can be synthesized from commercially available starting materials using custom synthesis methods. It is an API impurity and can be developed into a drug by researching and developing it as a niche therapy for hypertension. This compound has high purity and can be used as an HPLC standard.

Deschloro amlodipine is a drug that is used for the treatment of high blood pressure. It belongs to a group of drugs called calcium channel blockers. Amlodipine has been shown to bind to and inhibit the activity of voltage-gated calcium channels in heart muscle, thereby lowering blood pressure. Deschloro amlodipine is an impurity standard for pharmacopoeia and analytical laboratories. The synthesis of deschloro amlodipine can be customized according to customer requirements. This product will be shipped as soon as possible after purchase.br> br> Desloro amlodipine is metabolized by cytochrome P450 enzymes, including CYP3A4, CYP2C9, and CYP2D6, which are found in the liver and intestines. These enzymes convert desloro amlodipine into two metabolites: 4-hydroxyamlodipine and 4

Ivermectin is a drug that belongs to the anthelmintic class of drugs. It is active against roundworms, pinworms, and hookworms. Ivermectin has been shown to have an effect on autoimmune diseases such as multiple sclerosis, systemic lupus erythematosus, and rheumatoid arthritis by inhibiting the inflammatory response. The drug has been shown to inhibit matrix metalloproteinases in vitro and in vivo. The matrix effect is seen when the drug binds to proteins in the blood plasma or tissue matrix, where it inhibits their activity. This inhibition prevents the degradation of collagen, which can lead to tissue damage or renal failure. Ivermectin also binds to striatal dopamine receptors and inhibits dry weight gain in animals infected with Ostertagia ostertagi. Ivermectin is given orally in a single dose of 200 micrograms/kg body weight for treatment of intestinal worms (roundworm,

(2S,4R)-Fosinopril sodium salt is a prodrug that is converted to the active form fosinopril in the body. It is used to treat high blood pressure and heart failure. Fosinopril inhibits angiotensin-converting enzyme (ACE) and blocks the conversion of angiotensin I to angiotensin II. This leads to an increase in the production of a vasodilator called nitric oxide, which relaxes and widens blood vessels. Fosinopril also has been shown to have adverse effects on liver function, including increased liver enzymes and liver damage, as well as drug interactions with other nonsteroidal anti-inflammatory drugs (NSAIDs).

CPI 0610 is a medicinal compound that acts as a potent inhibitor of protein phosphorylation. It has been shown to inhibit the cell cycle and promote apoptosis in Chinese hamster ovary cells. CPI 0610 is an effective inhibitor of kinase activity in cancer cells, leading to decreased tumor growth and increased survival rates. In preclinical studies, CPI 0610 has demonstrated efficacy against a wide range of cancers, including breast, prostate, and lung cancer. This inhibitor has also been shown to be effective in human cancer cell lines, making it a promising candidate for future cancer therapies.

Ciprofibrate methyl ester is an analytical standard that can be used for the detection of impurities in drug products. It is a metabolite of Ciprofibrate and is used as a reference material for HPLC. The impurity standards are available in high purity or with different levels of purity, depending on the application. In addition, it can be custom synthesized to meet specific needs. This product has been tested according to the requirements of the USP-NF and has been found to meet these requirements.

Pidotimod Diketopiperazine is a test substance that is a phosphoric acid salt of pidotimod with a diketopiperazine group. Pidotimod Diketopiperazine has an elution time of approximately 3 minutes, on the Agilent HPLC column. It is soluble in water and has a pH of around 1.5-2.5. Pidotimod Diketopiperazine is used to solubilize phosphoric acid and can be used as an eluant for phosphoric acid in HPLC analysis.

1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]thio]-1H-benzi midazole is a high purity analytical standard that is used to calibrate HPLC. It is found as an impurity in the drug product and as a metabolite. 1-[(3-Methyl-4-(2,2,2 -trifluoroethoxy) - 2 - pyridinyl) methyl] - 2 - [[[3 - methyl (4 ( 2 , 2 , 2 - trifluoroethoxy) - 2 pyridinyl) methyl] thio] - 1 H benzimidazole is the IUPAC name for this compound. This chemical has been synthesized

Remdesivir related compound 7 is a drug product that is being synthesized for use in research and development. The synthesis of this compound will be carried out with an analytical purity of greater than 98%. This custom synthesis is not a natural product and has been designed for use in pharmacopoeia. Remdesivir related compound 7 metabolizes to form metabolites that are impurities. It is an API impurity that can be used as a synthetic standard or impurity standard for HPLC testing.

4-[2-[[(6R,7R)-7-Amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]thio]-4-thiazolyl]-1-methylpyridinium Chloride Monohydrochloride is a drug product under development for the treatment of bacterial infections. 4-[2-[(6R,7R)-7Amino--2carboxy8oxo5thia1azabicyclo[4.2.0]oct2en3yl]thio]-4thiazolyl]-1methylpyridinium Chloride Monohydrochloride is an impurity in the API Methicillin (CAS No. 40082764). Impurities are not necessarily undesirable and may have substantial therapeutic value or provide a desired

Amoxicillin EP Impurity L is an impurity standard for amoxicillin. It is a synthetic compound that is used to ensure the quality of amoxicillin drug products. Amoxicillin EP Impurity L has been shown to be metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. This impurity has also been shown to have anti-inflammatory properties and may be due to its inhibition of prostaglandin synthesis.

Fosfomycin trometamol EP impurity A disodium is a research and development impurity standard. It is a custom synthesis that is used as a drug product, synthetic, high purity, pharmacopoeia, drug development, metabolite, niche, analytical and natural. Fosfomycin trometamol EP impurity A disodium has been shown to have an HPLC standard and CAS No. 84954-80-3(free base).

4,7-Dihydro megestrol acetate is a drug product that has been custom synthesized for research and development purposes. It is an analytical standard with a purity of ≥99% and a CAS number of 14994-27-5. Metabolism studies have been conducted in both rats and mice to determine the metabolic pathway of 4,7-dihydro megestrol acetate. The metabolites found in this study were 4,7-dihydro megestrol and the acetate ester of 4,7-dihydro megestrol. Metabolite standards are used to identify substances produced by metabolism or chemical reactions in biological samples. These standards are used as reference points for measuring the concentration or quantity of other substances in biological samples. Pharmacopoeia standards are used to verify the quality of drugs, food additives, ingredients, and other substances. They also serve as reference points for identifying impurities in substances that may be harmful

Please enquire for more information about Pregabalin inhouse impurity (RS-mme) including the price, delivery time and more detailed product information at the technical inquiry form on this page

3-Keto fluvastatin sodium is a high purity, analytical, API impurity, HPLC standard, Drug development, niche, drug product and Impurity standard. 3-Keto fluvastatin sodium is used in the research and development of drugs. It is also used in the analysis of pharmaceuticals and other chemicals. 3-Keto fluvastatin sodium has been shown to have pharmacological properties with respect to lowering cholesterol levels.

Carfilzomib is a drug product that belongs to the class of drugs called proteasome inhibitors. It has been used in the treatment of multiple myeloma, and is also being studied for use in other diseases such as chronic obstructive pulmonary disease and cystic fibrosis. Carfilzomib is an impurity standard for HPLC analysis and an analytical reference material. It is also used as a pharmacopoeia reference material. Carfilzomib is a natural product, with the synthetic route being developed by researchers at Pfizer. The drug product contains 2R,4S-diol as its main metabolite and impurity.

Desfluoro impurity is a drug product that is an analytical standard for the identification of impurities in API. It is a natural, synthetic, and custom synthesis impurity with CAS 915087-16-0. This product is used for drug development, research and development, and niche applications. Desfluoro impurity is also an HPLC standard and has pharmacopoeia purity.

Boc-3-hydroxy-1-adamantyl-glycine is a catalytic, nucleophilic, chiral amino acid that is used in the synthesis of oximes. Boc-3-hydroxy-1-adamantyl-glycine has been shown to be an effective substitute for hydroxylamine in reductive amination reactions and can be used to synthesize some pharmaceuticals, including saxagliptin. This compound is stable under standard conditions and can be easily synthesized. It is also a powerful nucleophile that reacts with electrophiles such as chloroformates and sulfonyl chlorides.

Rac5-Keto Fluvastatin is a synthetic, natural and custom synthesis drug product. It's CAS number is 1160169-39-0. Rac5-Keto Fluvastatin is a metabolite of fluvastatin. The racemic mixture has been prepared by the organic synthesis of racemic 5-keto fluvastatin, which was achieved by the use of a chiral auxiliary. Rac5-Keto Fluvastatin can be used in metabolism studies, as an analytical standard for HPLC, and as a reference material for pharmacopoeia.

Sunitinib impurity G is a research and development impurity that is found in the process of synthesizing sunitinib. Sunitinib impurity G is an analytical standard that is soluble in methanol and is suitable for HPLC analysis. It has been shown to have high purity, excellent stability, and a low level of toxicity.

6-Acetoxymethyl-4-methoxy-5-methyl-3-pyridylmethanol o-toluate is a synthetic compound that is used as an analytical reference standard for the metabolism studies. It has been evaluated in a pharmacopoeia and has been found to be of high purity with no detectable impurities. This product can be used in drug development or research and development.

Valganciclovir related compound G is a drug product. It has been synthesized in our lab. Valganciclovir related compound G is not an approved drug and is not currently available in the market. Valganciclovir related compound G is a high purity analytical standard that can be used for metabolism studies, natural product research, synthetic research, and pharmacopoeia. Valganciclovir related compound G is a metabolite of valganciclovir and can be used as an impurity standard for HPLC analysis.

Lisinopril is a drug product that is used to treat high blood pressure, heart failure and other conditions. It belongs to the class of angiotensin-converting enzyme inhibitors and has been shown to inhibit the activity of angiotensin I converting enzyme (ACE) in the body, which leads to increased levels of bradykinin, an important peptide in inflammation. Lisinopril is a metabolite of cilazapril and lisinoprilat, both of which are prodrugs. Lisinopril has been shown to be effective in reducing blood pressure and improving survival rates in patients with heart failure.

Remdesivir impurity 3 HCl is a drug product that is a metabolite of Remdesivir. It has been shown to be a natural, synthetic and research and development impurity standard for HPLC analysis. CAS No.: 2096981-79-0

N-[1-[3-(4-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4-fluoro-N-(3-pyridinylmethyl)-3-(trifluoromethyl)-benz eneacetamide is a drug product that is used in the development of new drugs. It is an analytical standard for HPLC and was created as a natural metabolite from the antibiotic Cefazolin. N-[1-[3-(4-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4 -fluoro -N-(3 -pyridinylmethyl) - 3 (trifluoromethyl) - benzeneacetic acid has been shown to inhibit

Oxybutynin EP impurity A is a metabolite of oxybutynin, an antispasmodic drug. It has been shown to have immunomodulatory effects in a rat model of adjuvant arthritis. Oxybutynin EP impurity A is the major metabolite of oxybutynin and has been shown to be pharmacologically active in humans.

Please enquire for more information about (E)-2-Furaldehyde, (2,4-dinitrophenyl)hydrazone including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-[[4-(2-Pyridylsulfamoyl)phenyl]azo]hydroxybenzene is an impurity found in sulfasalazine. It is a metabolite that is formed by the P450 system in the liver. The metabolic process of 2-[[4-(2-Pyridylsulfamoyl)phenyl]azo]hydroxybenzene has been studied in detail and has been shown to be a major contributor to the pharmacokinetic profile of sulfasalazine. This substance also exhibits antimicrobial activity and inhibits the growth of bacteria, fungi, and viruses.

Remdesivir impurity 5 is a metabolite that is generated in the body following metabolism and excretion of remdesivir. It has been shown to be present in urine, plasma, and cerebrospinal fluid following administration of remdesivir. Remdesivir impurity 5 binds to the active site of HIV reverse transcriptase with a Kd value of 0.5 nM. The chemical name for this compound is (5R)-3-[[3-[(2S,4R)-2-amino-4-(2-methylpropyl)piperidin-1-yl]-1H-indol-6-yl]carbonyl]benzoic acid methyl ester.

Doxorubicin impurity 15 is a natural product that is used as an analytical reference standard in pharmacopoeia. It has been synthesized for use in drug development and research and development, and is available as a high-purity HPLC standard. Doxorubicin impurity 15 has a CAS number of 131086-18-5.

N-Desmethyl trimeprazine is a synthetic compound, which is an impurity of the drug product. It is not active and does not possess any biological activity. It is a metabolite of the parent drug, Trimeprazine. N-Desmethyl trimeprazine has been studied for its pharmacological properties and metabolism in the body, but no conclusive results have been found. The chemical structure and purity of N-Desmethyl trimeprazine are not listed in the USP or BP. This compound can be custom synthesized on request.

Cervicarcin is a potent inhibitor of human kinases and a promising analog for the treatment of tumors. This compound has been shown to induce apoptosis in cancer cells and inhibit the growth of tumors in Chinese hamsters. Cervicarcin is an anticancer agent that inhibits the activity of specific kinases involved in cell proliferation, differentiation, and survival. It has been shown to be effective against a variety of cancers, including cervical cancer, breast cancer, and lung cancer. The mechanism of action involves the inhibition of ghrelin-induced kinase activation, which leads to the suppression of tumor growth. Cervicarcin is obtained from cellulose by extraction from urine and has shown great potential as an inhibitor for the treatment of various types of cancer.

Sr 33805 oxalate is a potent inhibitor of cell proliferation that is used in the treatment of cancer. It has been shown to inhibit tumor growth and invasion in vivo by binding to the beta-subunit of voltage-gated potassium channels, which leads to decreased cellular proliferation and autophagy. Sr 33805 oxalate also inhibits cancer cells by inhibiting mitosis and inducing apoptosis. This agent has cytotoxic effects on brain cells, with an IC50 value of 0.1 μM in vitro against rat cerebellar neurons. In addition, it has been shown to be highly selective for cancer cells over normal brain tissue in vivo, with a potency that is 10 times greater than gatifloxacin.

Pyrrolo[1,2-f][1,2,4]triazin-4-amine is a small molecule that inhibits the proliferation of leukemia cells as well as other tumor cells. It inhibits the replication of viruses in vitro and has been shown to inhibit the growth of viruses in cell culture. This compound also binds to phosphonates and can be used as an inhibitor in assays to measure phosphonate activity. Pyrrolo[1,2-f][1,2,4]triazin-4-amine has also been shown to have inhibitory properties against cancer cells in vivo and can be used to treat cancer. In addition, this compound reacts with hydroxyl groups by epimerization reactions and benzyl groups by substitution reactions.

(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is a chiral molecule with four stereocenters. It is synthesized by the reaction of sulfamic acid and cyclohexene in the presence of p-toluenesulfonic acid. The product formed is then dehydrogenated to produce (R)-1-phenyl-1,2,3,4-tetrahydroisoquinoline. This compound is soluble in organic solvents such as benzene and ethane and can be used as an acceptor for chiral stationary phases.

Tenofovir disoproxil is the disoproxil fumarate salt of tenofovir. It is a nucleoside reverse transcriptase inhibitor that has been shown to be effective in the treatment of chronic hepatitis B virus (HBV) in combination with emtricitabine and as a single agent in the treatment of HIV-1 infection. Tenofovir disoproxil is available as tablets, capsules, or oral solution. The drug has been shown to cause an increase in serum creatinine levels, which may be due to inhibition of renal tubular secretion of creatinine by tenofovir. This drug should not be used with alafenamide and tenofovir because it can lead to kidney failure and death.

Please enquire for more information about 2-[4-(Dimethylamino)-1-(2-methylphenyl)butyl]-phenol including the price, delivery time and more detailed product information at the technical inquiry form on this page

Methyl 2-hydrazinecarboxylate, also known as methylene diazohydroxide, is a synthetic compound. It has been used in research and development as an analytical standard and impurity standard for HPLC methods.

(3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl[(2-hydroxy-2-methylpropyl)sulfonyl]amino]-5-pyrimidinyl]-3,5-dihydroxy- 6-heptenoic acid sodium salt is a synthetic drug product. It is an impurity standard in the synthesis of Metabolism studies. The CAS number is 1714147-50-8 and the chemical name is (3R,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl[(2-hydroxy-2 methylpropyl)sulfonyl]amino]-5-pyrimidinyl]-3,5dihydroxyheptenoic acid sodium salt. The molecular weight is 781

Please enquire for more information about N-Carboxylate-6-hydroxy melatonin ethyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page

Pseudomonic acid D sodium is a drug product that is used for the development of novel drugs. It is a natural metabolite of pseudomonic acid A, which is found in the fungus Pseudomonas sp. Pseudomonic acid D sodium is used as an analytical standard to aid in the identification of pseudomonic acid A and its metabolites. Pseudomonic acid D sodium can be synthesized by reacting 2-chloro-4-nitrobenzene with sodium bisulfate. The synthesis proceeds through a sequence of three reactions, namely nucleophilic substitution, electrophilic substitution, and hydrolysis. The structure of pseudomonic acid D sodium has been confirmed using nuclear magnetic resonance spectroscopy (NMR) and mass spectrometry (MS).

Lysolecithin is an analog of the phospholipid lecithin that has been shown to have anticancer properties. It works by inhibiting kinases, which are enzymes that play a crucial role in cell signaling and regulation. Lysolecithin promotes apoptosis, or programmed cell death, in cancer cells, making it a promising medicinal agent for the treatment of tumors. Studies have also shown that lysolecithin can inhibit protein kinase activity in human urine and inhibit the growth of cancer cells in Chinese hamsters. This compound may prove to be a valuable tool in the development of kinase inhibitors for cancer therapy.

Please enquire for more information about (S)-Carisbamate β-D-o-glucuronide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Acrolein-d4 including the price, delivery time and more detailed product information at the technical inquiry form on this page

Alpha-Desmethyl anastrozole is a synthetic chemical that has been used as an impurity standard for the drug product, Anastrozole (Arimidex). This compound is metabolized in humans and is a metabolite of Arimidex. Alpha-Desmethyl anastrozole exhibits high purity and can be synthesized using custom synthesis. The CAS number for this compound is 1215780-15-6.

Tolterodine S-enantiomer is a drug product that belongs to the class of prodrugs. It is metabolized in vivo to the active form, tolterodine. Tolterodine S-enantiomer has been shown to have a natural origin and can be found in plants and animals. Metabolism studies of this compound have been conducted in human liver microsomes, with the major metabolite being tolterodine. Tolterodine S-enantiomer also has pharmacopoeia standards, including an analytical standard and an impurity standard, as well as an HPLC standard for research and development purposes.

Hydroxy cyclophosphamide semicarbazone-d4 is an analytical standard used to monitor the purity of a drug product. It can be used as a reference compound to determine the identity of impurities in a drug product. Hydroxy cyclophosphamide semicarbazone-d4 has been found to be an impurity in some drugs, such as dihydroxycyclophosphamide and hydroxyclorambucil. The chemical name for this substance is 4-[bis(2-chloroethyl)amino]benzoic acid hydroxycyclobutyl ester, and it is used in the synthesis of 3-(1-naphthyl)propionic acid semicarbazide and 2-methyl-2-nitropropane sulfonate. Hydroxy cyclophosphamide semicarbazone-d4 is also a metabolite that is formed when hydroxy cyclophosphamide is broken down by the liver or kidney.

Quetiapine is a drug that belongs to the class of sulfoxides. It is usually administered orally, but can also be given intravenously or intramuscularly. Quetiapine has been studied for its clinical use in the treatment of schizophrenia and bipolar disorder. The plasma concentrations of quetiapine are determined by high-performance liquid chromatography (HPLC) with tandem mass spectrometry (LC-MS/MS) detection. Validation studies have shown that the HPLC-MS/MS method is accurate and precise, with good linearity over a range of concentrations. Analysis was performed on plasma samples from healthy volunteers who were administered either 2 mg or 10 mg doses of quetiapine by intravenous injection. Concentrations were calculated and compared to those found in patients with schizophrenia and bipolar disorder who had been given oral doses of 300 mg per day for four weeks, yielding a therapeutic plasma concentration range from 100 to 300 ng/mL.

Cis-Tadalafil is a potent inhibitor of phosphodiesterase 5, which is used to treat erectile dysfunction (ED) and primary pulmonary hypertension (PPH). It works by increasing blood flow to the penis, allowing men with ED to achieve and maintain an erection. Cis-Tadalafil is also used to treat symptoms of prostatic hyperplasia (enlarged prostate) in men. This drug has been shown to be effective in treating PPH by reducing pulmonary arterial pressure and improving exercise capacity. Cis-Tadalafil belongs to the carboline class of drugs and is a phosphodiesterase 5 inhibitor that selectively inhibits cGMP-specific phosphodiesterase type 5 (PDE5). This drug has been shown to be highly effective in treating both ED and PPH with minimal side effects.

Sacubitril Impurity 2 is a drug product that is an analytical impurity in Sacubitril. This impurity can be found in Sacubitril as a result of natural processes or as an API impurity during the synthesis process. Sacubitril Impurity 2 has been shown to have activity in Metabolism studies, Natural, and Custom synthesis. It has been shown to be a Synthetic impurity standard and HPLC standard. Sacubitril Impurity 2 is used for research and development purposes for the drug development industry, specifically for the niche market. It is also used as an analytical standard for pharmacopoeia methods.

N-Nitroso dorzolamide is a chemical compound used as an intermediate in the synthesis of dorzolamide, a carbonic anhydrase inhibitor used in the treatment of glaucoma and ocular hypertension.

Acarbose Impurity E is an impurity found in acarbose. It is a natural, API impurity and is a synthetic impurity standard. Acarbose Impurity E has been used in drug development research and development, as well as in the HPLC analysis of acarbose to generate a pharmacopoeia-grade purity standard.

Linagliptin impurity G is an impurity in the drug product Linagliptin. It is a natural substance and its CAS number is 668270-11-9. Impurity G can be synthesized from L-phenylalanine and cyclohexane carboxaldehyde in a two step process. The first step involves the reaction of L-phenylalanine with cyclohexane carboxaldehyde to yield methylcyclohexanecarboxylate, which then undergoes hydrolysis to give phenylcyclohexanol. In the second step, phenylcyclohexanol reacts with hydrochloric acid to produce phenylcyclohexanone, which is then oxidized with hydrogen peroxide to yield impurity G. Impurity G can also be found in the pharmacopoeia as a high purity HPLC standard for linagliptin.

Please enquire for more information about (4-Chlorophenyl)diphenylmethanol including the price, delivery time and more detailed product information at the technical inquiry form on this page

N-Hydroxymethyl Sumatriptan is an analytical standard and a research and development impurity. It is also used as an API impurity in drug product manufacturing. N-Hydroxymethyl Sumatriptan can be synthesized by reacting the parent drug with hydroxyl radicals, which is a process that yields no side products. N-Hydroxymethyl Sumatriptan can be found in the following pharmacopoeia: United States Pharmacopoeia (USP) 11>, European Pharmacopoeia (EP), Japanese Pharmacopoeia (JP)13>, British Pharmacopoeia (BP), and Chinese Pharmacopiae (CPC).

N-Benzyl albuterol is a drug product that is custom synthesized to be of high purity with an analytical standard. It is used in research and development, pharmaceutical development, and as a pharmacopoeia or analytical standard. N-Benzyl albuterol has been found to be a metabolite of the drug product Albuterol Sulfate. It is also used in metabolism studies and natural product research. The CAS number for this compound is 24085-03-8.

Desfluoro ezetimibe is a synthetic cholesterol-lowering drug that inhibits intestinal cholesterol absorption. It is chemically synthesized, and the process includes the introduction of fluorine at the 3-position of the C-ring. Desfluoro ezetimibe is not metabolized in humans, but it may be subject to oxidative degradation. The product is also subject to oxidation by light and air, which may result in formation of impurities. The drug substance has been validated as well as its isomers and efficiencies in mass spectrometry detection.

Ivermectin impurity I is an analytical standard that is used for pharmacopoeia and custom synthesis. It is a natural metabolite of the drug Ivermectin, which has been shown to have anti-inflammatory properties in mice. Ivermectin impurity I binds to nicotinic acetylcholine receptors, leading to muscle paralysis and death. This compound is found in high purity for research and development purposes.

Simvastatin acid is the active form of simvastatin, a drug used to lower blood cholesterol levels. Simvastatin acid inhibits HMG-CoA reductase, the enzyme that converts HMG-CoA to mevalonate. This conversion is a rate-limiting step in the synthesis of cholesterol and other lipids. Simvastatin acid binds to polymerase chain and drug transporter proteins, which leads to cell lysis. The concentration–time curve for simvastatin acid is linear and the half-life is approximately 12 hours. When simvastatin acid is administered with drugs that are potent inducers of CYP3A4 or UGT1A1 enzymes, there may be an increased risk for drug interactions. Simvastatin acid has shown no significant human pharmacokinetic interactions with food or grapefruit juice at doses up to 200 mg/day. There are limited data on the pharmacokinetics of simvastatin

N-Desacetyl thiocolchicoside is a white crystalline powder that is soluble in water, methanol and acetone. It has a molecular weight of 320.2 and an empirical formula of C6H14O5. N-Desacetyl thiocolchicoside is used as an analytical standard for HPLC analysis, as a Research and Development (R&D) material for drug development, and as an impurity standard for the manufacture of pharmaceutical products. This compound has been shown to be a metabolite of thiocolchicoside and structurally similar to the drug product chitinase.

Please enquire for more information about Oxacyclohexane open ring tacrolimus including the price, delivery time and more detailed product information at the technical inquiry form on this page

Roflumilast impurity A is a metabolite of roflumilast. It is a drug product that is used as an analytical standard for the determination of roflumilast in HPLC analysis. Roflumilast impurity A is not natural and is synthetic. It has been shown to be a substrate for CYP1A2, CYP2C8, CYP2C9, and CYP3A4 enzymes. Studies have shown that it may be involved in the metabolism of roflumilast through hydroxylation and deamination.

2-(2-Amino-5-bromobenzoyl)pyridine (2ABBP) is a chemical compound with the molecular formula C10H7BrN3. It is a glucuronide conjugate of 2-amino-5-bromobenzoic acid and has been used as an immunological reagent in the form of a monoclonal antibody. 2ABBP binds to dryopteris, which is a plant species that contains polyphenols called pteridines. 2ABBP has been shown to have anti-inflammatory properties in rat liver microsomes and cell culture experiments. The mechanism of action may involve inhibition of cyclooxygenase enzymes, which are involved in prostaglandin synthesis. 2ABBP also binds to human serum albumin and chaperones, proteins that bind other proteins or small molecules. The biological activity of 2ABBP may be due to its ability to form coval

Ciprofloxacin ep impurity C is a synthetic compound. It is used as a research and development standard in the synthesis of ciprofloxacin. The purity of this compound is high, and it has been tested for metabolism studies. This impurity can be detected by HPLC using an analytical method with a natural reference substance. This impurity has not been evaluated for pharmacopoeia or CAS number.

Piperacilloic acid is a synthetic compound that exhibits antibacterial activity. It has been shown to be effective against human pathogens, including urothelial carcinoma and human serum. Piperacilloic acid binds to the amino acids lysine and arginine in bacterial proteins and inhibits protein synthesis by inhibiting the function of enzymes that require these amino acids for their activity. The potency of piperacillin is low, but it is activated by hydrolysis in the acidic environment of the stomach or intestinal tract. Piperacilloic acid also has potential as a contraceptive agent because it may inhibit transcriptional regulation of genes that are involved in sperm production.

Empagliflozin S-furanose is a Custom synthesis drug product. It is an analytical standard with CAS No. 1620758-32-8, and it is used in research and development of new drugs. Empagliflozin S-furanose has been found to be a metabolite of empagliflozin, a drug that is used to treat type 2 diabetes mellitus. It is also used as an impurity standard for HPLC analysis of empagliflozin because it does not have any biological activity.

Terbinafine is a drug used in the treatment of onychomycosis, tinea versicolor and dandruff. It belongs to the group of medicines known as antifungals and inhibits the growth of fungi by inhibiting their ability to make proteins. Terbinafine dihydrochloride is a form of terbinafine that is more soluble in water than terbinafine hydrochloride and can be used as a lubricant. Terbinafine hydrochloride is an industrial product that is used as a disintegrant in tablets and capsules.

(S)-Rabeprazole sodium is an anticancer drug that acts as a kinase inhibitor. It is an analog of Rabeprazole and has been shown to inhibit the growth of cancer cells in vitro and in vivo. (S)-Rabeprazole sodium inhibits the activity of kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. (S)-Rabeprazole sodium has been tested against various types of cancer, including Chinese hamster ovary cells and tumor xenografts in mice. It has also been shown to inhibit elastin degradation, which is important for preventing metastasis of cancer cells. (S)-Rabeprazole sodium may be a promising candidate for the development of new anticancer drugs that target specific kinases and proteins involved in cancer cell growth and survival.

Tofacitinib dihydro impurity is a research and development impurity standard for the synthesis of Tofacitinib. It is a custom synthesis with high purity, pharmacopoeia grade, and synthetic. This product is also used in drug development for metabolism studies and analytical applications.

(3S,4R)-Tofacitinib is a rhombic and paramagnetic compound with a Curie point of approximately 10.6°C. It is soluble in nonpolar solvents such as benzene and toluene. (3S,4R)-Tofacitinib has been shown to have magnetic properties that are dependent on the temperature and the frequency of the applied magnetic field. The paramagnetic resonance spectra were observed at 18°C and 32°C, while the paramagnetic resonance spectrum was observed at -2°C. The octahedral interactions are likely due to the presence of six different types of iron ions in the crystal structure.

Dicyclopropylamine hydrochloride is a tyrosine kinase inhibitor that blocks the activity of jak2. It is an innovative molecule with the potential to be used in cancer treatment. Dicyclopropylamine hydrochloride has been shown to inhibit activation of tyrosine kinases, which are involved in cell signaling and proliferation. Dicyclopropylamine hydrochloride also has anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. This drug is not expected to have any toxicity or side effects because it can be easily metabolized by the liver.br>br> Dicyclopropylamine hydrochloride is a white solid with a melting point of 175°C. It has no detectable odor, and it is soluble in water and ethanol. The impurities found in this compound include myristic acid and amines, which can cause inflammatory diseases.br>br> D

Pramipexole EP Impurity C is a synthetic impurity that is used as an impurity standard in the manufacture of Pramipexole EP. It is also used as a research and development tool for drug product, custom synthesis, CAS No. 1973461-14-1, and analytical studies. This compound has been shown to be a metabolite of Pramipexole EP and may have pharmacological properties. Pramipexole EP Impurity C has been found to inhibit the growth of certain bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA) isolates.