APIs pour la recherche et les impuretés
Les principes actifs pharmaceutiques (API) sont les substances présentes dans les médicaments qui sont responsables de leurs effets thérapeutiques. Dans cette section, vous trouverez une grande variété d'API destinés à un usage de recherche. Ces composés sont essentiels pour le développement, les tests et la validation de nouvelles formulations pharmaceutiques. Chez CymitQuimica, nous proposons des API de haute qualité pour soutenir la recherche dans la découverte et le développement de médicaments.
Sous-catégories appartenant à la catégorie "APIs pour la recherche et les impuretés"
- Acides Aminés et Dérivés(12.332 produits)
- Anthraquinones et Dérivés(404 produits)
- Dérivés du Benzimidazole et de l’Imidazole(10.439 produits)
- Dérivés des Benzodiazépines(333 produits)
- Glucides et Glycoconjugués(5.051 produits)
- Esters et Dérivés(42.250 produits)
- Acides Gras et Dérivés Lipidiques(32.408 produits)
- Flavonoïdes et Polyphénols(17.081 produits)
- Radicaux Libres et Agents Oxydants/Réducteurs(212 produits)
- Cétones et Dérivés(2.399 produits)
- Antibiotiques Naturels et Semi-Synthétiques(6.376 produits)
- Nitriles et Dérivés Cyano(3.068 produits)
- Nitrosamines et Dérivés(55 produits)
- Nucléosides et Nucléotides(3.471 produits)
- Phosphates et Phosphonates Organiques(1.200 produits)
- Sulfonates et Sulfates Organiques(10.430 produits)
- Composés Organométalliques(4.421 produits)
- Autres(6.300 produits)
- Peptides et Protéines(3.146 produits)
- Polymères et Dérivés(100 produits)
- Dérivés des Purines et Pyrimidines(8.940 produits)
- Dérivés de Quinazoline et de Quinoléine(65.982 produits)
- Quinones et Dérivés(24.359 produits)
- Sels et Dérivés d’API(80.669 produits)
- Stéroïdes et Dérivés(4.952 produits)
- Sulfamides et Dérivés(2.589 produits)
- Terpénoïdes et Dérivés(3.846 produits)
- Thiazolidinediones et Thiopyranes(2.753 produits)
- Composés β-Adrénergiques(231 produits)
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58005 produits trouvés pour "APIs pour la recherche et les impuretés"
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Des-Glu(3)-Semaglutide
Des-Glu(3)-semaglutide is a semaglutide-related impurity. This des-amino acid form has got the glutamic acid or glutamate (Glu) amino acid from position 3 removed from the peptide chain. Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist used for managing type 2 diabetes and obesity.Formule :C182H284N44O56Masse moléculaire :3,984.53 g/molD-His(1)-Semaglutide
D-His(1)-Semaglutide is a semaglutide impurity. The amino acid at position 1 has been replaced by the D-form of the amino acid D-histidine (D-His). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.Formule :C187H291N45O59Masse moléculaire :4,113.64 g/molLinear Semaglutide
Linear semaglutide, or simply L-Sema, is the semaglutide compound without the lipid side chain modification. It is essentially a linear version of the peptide.Formule :C152H230N42O47Masse moléculaire :3,397.76 g/molSemaglutide Impurity 54 (D-Ala 18)
D-Ala(18)-Semaglutide is a semaglutide impurity. The amino acid at position 18 has been replaced by the D-form of the amino acid D-alanine (D-Ala). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.Formule :C187H291N45O59Masse moléculaire :4,113.64 g/molD-Ala(24)-Semaglutide
D-Ala(24)-Semaglutide is a semaglutide impurity. The amino acid at position 24 has been replaced by the D-form of the amino acid D-alanine (D-Ala). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.Formule :C187H291N45O59Masse moléculaire :4,113.64 g/molD-Asp(9)-Tirzepatide
Tirzepatide impurity.Formule :C225H348N48O68Couleur et forme :PowderMasse moléculaire :4,813.5 g/molN-(Aminosulphonyl)-3-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]propanamide, hydrochloride
CAS :Famotidine is a histamine H2 receptor antagonist. It is used to prevent stomach ulcers, heartburn, or "acid indigestion." Famotidine is available in various forms for oral administration: tablets, capsules, and solution. The chemical name for famotidine is N-(aminosulphonyl)-3-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]propanamide hydrochloride.Formule :C8H15ClN6O3S3·HClDegré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :411.35 g/mol1-Phenyl-1-(2-pyridinyl)ethanol hydrochloride
CAS :1-Phenyl-1-(2-pyridinyl)ethanol hydrochloride is a natural product that is used as a pharmacopoeia standard for analytical and HPLC applications. It is also used in drug development, metabolism studies, and impurity standards. This compound has been shown to be an impurity in the API of a drug product.Formule :C13H13NO·HClDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :235.71 g/molN-[2-[[[5(Dimethylamino)methyl]-2-furanyl]thio]ethyl]-N'-methyl-2-nitro-2,2-ethendiamine, S-oxide
CAS :N-[2-[[[5(Dimethylamino)methyl]-2-furanyl]thio]ethyl]-N'-methyl-2,2-ethendiamine, S-oxide is a chemical compound that has been shown to be an effective inhibitor of the metabolism of many drugs in rat liver microsomes. This drug is used as an analytical method in urine samples to study the clinical relevance of n-oxide metabolites and their effects on drug interactions. N-[2-[[[5(Dimethylamino)methyl]-2-furanyl]thio]ethyl]-N'-methyl-2,2-ethendiamine, S-oxide has been shown to have optimum concentration at 0.1 mM in wastewater treatment systems. The kinetic data for this compound were obtained using a model system with low bioavailability.Formule :C13H22N4O4SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :330.4 g/molAmbroxol hydrochloride impurity B
CAS :Ambroxol hydrochloride impurity B is a byproduct of the chemical synthesis of Ambroxol hydrochloride. It is an organic compound that is a colorless, crystalline solid with a melting point of 93°C and a vapor pressure of 0.0012 mmHg at 25°C. The biological relevance and chronic bronchitis detection time of Ambroxol hydrochloride impurity B are unknown. Chemical reactions involving this compound include hydrolysis, oxidation, esterification, and reduction. Ambroxol hydrochloride impurity B has been detected in human blood plasma as well as in the lungs, liver, spleen, brain and kidney tissues following intravenous administration. This substance can be found as a metabolite in urine and feces following oral ingestion or injection.Formule :C14H19Br2ClN2ODegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :426.57 g/molAtorvastatin EP Impurity D
CAS :Soluble in Chloroform & in Methanol Confirmed
Insoluble in WaterDegré de pureté :95.0% MinCouleur et forme :White or Off-White Crystalline Solid, Light SensitiveMasse moléculaire :431,465-Benzamidolevulinic acid
CAS :5-Benzamidolevulinic acid is an ethylamine derivative that inhibits the enzyme carbonic anhydrase. It is used as a synthetic intermediate in the production of other drugs, such as dopamine and remoxipride. 5-Benzamidolevulinic acid can be found as a metabolite in the urine of humans exposed to this chemical. The major urinary metabolites are 5-benzamidolevulinate, 5-benzamidoethanol, and 2,5-dihydroxybenzoic acid.Formule :C12H13NO4Degré de pureté :Min. 95%Masse moléculaire :235.24 g/mol1-β-D-Ribofuranosyl-3-guanylurea picrate
CAS :Produit contrôlé1-beta-D-Ribofuranosyl-3-guanylurea picrate is also known as 1-(diaminomethylene)-3-(beta-D-ribofuranosyl)urea picrate, 1-amidino-3-b-D-ribofuranosylurea monopicrate and Azacitidine Related Compound C. 1-beta-D-Ribofuranosyl-3-guanylurea picrate is an impurity generated from the hydrolysis of the drug Azacitidine, available on the market with the trade name Vidaza. Azacitidine is a chemical analogue of cytidine and is used in the treatment of myelodysplastic syndrome.Formule :C7H14N4O5•C6H3N3O7Degré de pureté :Min. 95.0 Area-%Couleur et forme :PowderMasse moléculaire :463.31 g/mol3,3'-(3,6-Dihydropyrazine-2,5-diyl)dipropanoic acid
CAS :3,3'-(3,6-Dihydropyrazine-2,5-diyl)dipropanoic acid (DPPA) is a potent metal chelator that can be used in the treatment of cancer. DPPA binds to metal ions and prevents their access to vital cellular components such as DNA and proteins. This agent has been shown to inhibit the growth of carcinoma cells in culture. It also has an effect on the synthesis of demyelination, which may account for its ability to prevent reactive oxygen species from damaging DNA. DPPA is a strong inhibitor of mitochondrial function and at high concentrations it damages mitochondria by releasing hydrogen peroxide into the cell cytoplasm. The release of hydrogen peroxide causes catalase to become active, leading to cell death.Formule :C10H14N2O4Degré de pureté :Min. 95%Masse moléculaire :226.23 g/molN-Desmethyl galanthamine
CAS :Produit contrôléN-Desmethyl galanthamine is a plant alkaloid that is found in the Huperzia serrata plant. It has been shown to have cholinergic activity and calcium binding properties. N-Desmethyl galanthamine inhibits acetylcholinesterase, an enzyme responsible for the breakdown of acetylcholine, which is a neurotransmitter. This inhibition leads to increased levels of acetylcholine, which results in increased neuron stimulation and improved memory function. N-Desmethyl galanthamine also binds to β2 nicotinic receptor sites and blocks the binding of nicotine, leading to decreased nicotine dependence.
Formule :C16H19NO3Degré de pureté :Min. 95%Masse moléculaire :273.33 g/molTrityl olmesartan acid
CAS :4-(1-Hydroxy-1-methylethyl)-2-propyl-1[4-[2-(trityltetrazol-5-yl)phenyl]phenyl]methylimidazol-5-caboxylic acid (4MPPC) is a water soluble, clear liquid that is used as a solvent. It can be prepared by the reaction of sodium carbonate with an organic or inorganic salt solution in acetonitrile. The solvents are then removed using filtration and the final product is obtained by evaporation of the solvent. 4MPPC has been used in the preparation of medoxomil, which is an antibiotic that inhibits bacterial growth by binding to DNA gyrase and topoisomerase IV.Formule :C43H40N6O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :688.82 g/molLisdexamfetamine dimesylate impurity B
Lisdexamfetamine dimesylate impurity B is a high purity, synthetic, custom synthesis drug product. Lisdexamfetamine dimesylate impurity B is a metabolite of lisdexamfetamine and the impurity standard for lisdexamfetamine dimesylate. It is used in pharmacopoeia to develop drugs. Lisdexamfetamine dimesylate impurity B is also used in analytical studies such as HPLC standards.Degré de pureté :Min. 95%Olmesartan lactone impurity
CAS :Olmesartan lactone impurity is a high-purity, low-cost, and stable pharmaceutical intermediate. It is an ester of olmesartan and medoxomil. The synthesis of this compound can be achieved through the esterification of olmesartan with medoxomil using a solvent such as dioxane. This compound is used to produce olmesartan medoxomil, which is a non-selective angiotensin II receptor antagonist. Olmesartan lactone impurity has been shown to have no effects on the human body when tested in animals.Formule :C24H24N6O2Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :428.49 g/mol[(2-Butoxyethoxy)ethyl] 2-[(trifluoromethyl)phenylamino]benzoate
CAS :[(2-Butoxyethoxy)ethyl] 2-[(trifluoromethyl)phenylamino]benzoate is a synthetic chemical that is an impurity in the synthesis of the drug product, [(2-butoxyethoxy)ethyl] 2-[(trifluoromethyl)phenylamino]-benzoate. It is a white to off-white solid with a melting point of 53°C. The purity of this compound is high and it has been used as an analytical standard for HPLC. This compound also has niche application in pharmacopoeia and drug development.Formule :C22H26F3NO4Degré de pureté :Min. 95%Couleur et forme :Pale yellow to yellow liquidMasse moléculaire :425.44 g/molNaltrexone impurity F
CAS :Naltrexone Impurity F is a drug product that is an impurity standard for the analytical determination of Naltrexone in HPLC. It is a natural metabolite of naltrexone and has been shown to have pharmacological effects similar to those of naltrexone. Naltrexone Impurity F is used as an analytical reference material for the detection of naltrexone in pharmaceutical products.Formule :C20H23NO5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :357.4 g/mol4-(1-Hydroxy-1-methylethyl)-2-propyl-1[4-[2-(tetrazol-5-yl)phenyl]phenyl]methyl imidazole-5-carboxylate [4-[2-(tetrazol-5-yl)phenyl] phenyl]methyl
CAS :4-[2-(Tetrazol-5-yl)phenyl] phenyl]methyl is a metabolite of the drug product 4-(1-Hydroxy-1-methylethyl)-2-propyl-1[4-[2-(tetrazol-5-yl)phenyl]phenyl]methyl imidazole-5-carboxylate. 4-[2-(Tetrazol-5-yl)phenyl] phenyl]methyl is a yellowish solid with a melting point of 128°C and a molecular weight of 246.8 g/mol. The impurity standard for 4-[2-(Tetrazol-5-yl)phenyl] phenyl]methyl is available in the form of an analytical grade, HPLC standard, or pharmacopoeia grade.Formule :C38H36N10O3Degré de pureté :Min. 95%Couleur et forme :White to off-white solid.Masse moléculaire :680.76 g/molAcetaminophen acetate
CAS :Acetaminophen acetate is a cholinergic amine that binds to the active site of the enzyme acetylcholine esterase, preventing it from breaking down acetylcholine. Acetaminophen is used as a pain reliever and antipyretic agent. It is also used for its anti-inflammatory effects in the treatment of rheumatoid arthritis and other inflammatory conditions. Acetaminophen has been shown to have anticancer properties, which may be due to its ability to bind to cancer cells, inhibit their growth, and induce apoptosis. Acetaminophen acetate is also an acylation reaction product that can be isolated by liquid chromatography in phase with fluorescence properties.Formule :C10H11NO3Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :193.2 g/molDefluoro atorvastatin acetonide tert-butyl ester
CAS :Please enquire for more information about Defluoro atorvastatin acetonide tert-butyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C40H48N2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :636.82 g/molAmiodarone N-oxide HCl
CAS :Amiodarone N-oxide HCl is a class III antiarrhythmic drug that acts by slowing the heart rate and prolonging the time between heartbeats. It has been shown to be effective in treating atrial fibrillation, ventricular fibrillation, and atrial flutter. Amiodarone N-oxide HCl has significant cytotoxicity, which can lead to cardiomyopathy and myocardial infarcts. Due to its long half life, amiodarone can accumulate in the body and cause side effects such as pulmonary toxicity, gastrointestinal bleeding, thyroid dysfunction, or liver damage. It is not recommended for use in patients with structural heart disease or those taking nonsteroidal anti-inflammatory drugs (NSAIDs) because of an increased risk of adverse events.Formule :C25H29I2NO4HClDegré de pureté :Min. 95%Couleur et forme :Off-White To Yellow SolidMasse moléculaire :697.77 g/molLevonorgestrel EP Impurity P
CAS :Soluble in Chloroform & in Methanol Confirmed
Insoluble in WateDegré de pureté :90% minCouleur et forme :Off White or Beige SolidMasse moléculaire :312.45(1R,4S)-N-Desmethyl sertraline hydrochloride
CAS :Sertraline metaboliteFormule :C16H16Cl3NDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :328.66 g/mol(3S,5S)-Atorvastatin sodium salt
CAS :Atorvastatin is a statin drug that inhibits the enzyme HMG-CoA reductase, which is responsible for cholesterol synthesis. Atorvastatin is used to lower LDL cholesterol and total cholesterol levels in the blood. It also lowers triglyceride levels and raises HDL cholesterol levels. Atorvastatin has been shown to inhibit fibrinogen production, reduce TNF-α production, and improve body mass index (BMI) in obese patients. This drug has been shown to be effective in reducing the size of atherosclerotic lesions by decreasing the amount of cholesteryl esters transferred from high-density lipoprotein (HDL) to low-density lipoprotein (LDL). It has also been shown to inhibit collagen production and stimulate muscle cell proliferation.Formule :C33H34FN2NaO5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :580.62 g/mol5-Aminolevulinic acid hydrochloride
CAS :Photodynamic Therapy of Actinic Keratosis. Porphobilinogen synthase substrate that produces endogenous porphyrins useful for sensitizing cells in photodynamic therapy. Intermediate in heme and chlorophyll biosynthesis. Estimation of 5-aminolevulinic acid dehydratase. PBG formed in the assay is determined spectrophotometrically with Ehrlich's reagent. Used in Porphyrin test for differentiation of Haemophilus species. Enzymes that convert ALA to porphyrins in the biosynthesis of hemin (X factor) are not produced by H. influenzae, H.aegyptius and H. canis. These enzymes are produced by H. parainfluenzae, H. parahaemolyticus, H. gallinarum, H. parasuis, H. parahaemolyticus and H. aphrophilus. A positive reaction is indicated by an orange-red fluorescence.Formule :C5H10ClNO3Degré de pureté :Min. 98.0 Area-%Masse moléculaire :167.59 g/mol3-O-Methylcarbidopa
CAS :Produit contrôlé3-O-Methylcarbidopa is a drug that belongs to the class of dopa decarboxylase inhibitors. It is an inactive prodrug, which is converted into its active form by hydrolysis in the body. 3-O-Methylcarbidopa has been shown to have a plasma concentration that can be detected, with an elimination rate of about 4 hours. The active substance is found in the particle size range of 0.1 to 1 micrometer and can be analyzed using chromatographic methods. 3-O-Methylcarbidopa is primarily used for the treatment of Parkinson's disease, but also has potential applications in other diseases such as Alzheimer's disease, depression and schizophrenia.Degré de pureté :Min. 95%Masse moléculaire :240.262'-Deoxy-2',2'-difluorocytidine 5'-monophosphate
CAS :2'-Deoxy-2',2'-difluorocytidine 5'-monophosphate (CDFMP) is a potent antitumor agent that has been shown to have a strong anti-angiogenic effect. It inhibits the cancer cell's production of microvessels and interferes with the formation of new blood vessels from pre-existing ones, which can be used to deliver chemotherapy drugs to the tumor. CDFMP is synthesized by reacting 2'-deoxy-2',2'-difluorocytidine with phosphoric acid and then converting it into the monophosphate form using phosphorus oxychloride. This drug is also resistant to platinum-based chemotherapy agents, making it a promising drug for patients who are resistant to other treatments.Formule :C9H12F2N3O7PDegré de pureté :Min. 97 Area-%Couleur et forme :PowderMasse moléculaire :343.18 g/molN-Methyl-3-(1-naphthalenyloxy)-3-(3-thienyl) propanamine tartrate
N-Methyl-3-(1-naphthalenyloxy)-3-(3-thienyl) propanamine tartrate is an impurity standard used for the quantitative analysis of norephedrine in pharmaceutical products. It is also a metabolite of methamphetamine, which has been shown to have anti-inflammatory activities.Formule :C18H19NOS·C4H6O6Degré de pureté :Min. 95%Masse moléculaire :447.5 g/mol3,3',5,5'-Tetraiodothyroformic acid
CAS :Cymit Quimicaetic beta-D-glucosiduronic acidFormule :C13H6I4O4Degré de pureté :Min. 95 Area-%Couleur et forme :Off-White PowderMasse moléculaire :733.8 g/molFluticasone furoate impurity F
Fluticasone furoate impurity F is a synthetic, high-purity, pharmacopoeia grade drug product. It has been developed for research and development purposes only. Impurity standard: Fluticasone furoate impurity F is a metabolite of fluticasone furoate. Synthetic: Fluticasone furoate impurity F is a synthetic compound that has been custom synthesized to meet your requirements. Drug Development: Fluticasone furoate impurity F has been developed as a drug product to be used in the development of new drugs. Metabolism Studies: Fluticasone furoate impurity F can be used in metabolism studies and analytical determinations.END>>Degré de pureté :Min. 95%3-Amino-4,6-dihydro-1,2,6-thiadiazine-1,1-dioxide, hydrochloride
3-Amino-4,6-dihydro-1,2,6-thiadiazine-1,1-dioxide is an impurity that has been identified in the process of synthesizing a drug. The impurity is typically found in small quantities and is not expected to have any adverse effects on the drug product if present in concentrations below 0.1% (w/w). 3-Amino-4,6-dihydro-1,2,6-thiadiazine-1,1-dioxide can be synthesized from two other compounds: 4,6-Diaminohexane and thiosemicarbazide. The CAS number for this impurity is 53497–14–8.Formule :C3H8ClN3O2SDegré de pureté :Min. 95%Masse moléculaire :185.63 g/molEpirubicin impurity G
CAS :Epirubicin impurity G is a synthetic research and development impurity standard that is used in the manufacture of drug products, as well as in the development of new drugs. Epirubicin impurity G is a metabolite of epirubicin and has been shown to be an active inhibitor of DNA synthesis. Epirubicin impurity G may also have potential as an analytical standard for HPLC analysis.Formule :C54H58N2O22Degré de pureté :Min. 95%Masse moléculaire :1,087 g/mol5-(2-Fluorophenyl)-1H-pyrrole-3-carboxylic acid
CAS :5-(2-Fluorophenyl)-1H-pyrrole-3-carboxylic acid is a synthetic drug that is used as an impurity standard. It has been shown to be metabolized by CYP450 enzymes and glucuronidases, and can inhibit the enzyme glutathione reductase. 5-(2-Fluorophenyl)-1H-pyrrole-3-carboxylic acid also has been shown to have antiplatelet activity, which may be due to its ability to inhibit the enzyme ADP cyclase.Formule :C11H8FNO2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :205.18 g/mol{(5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-1.3-oxazolidin-5-yl}methyl acetate
CAS :This product is a metabolite of the drug product and impurity standard. It has been synthesized as a custom synthesis to meet the needs of research and development, pharmacopoeia, or natural products. This compound is an API impurity that has been characterized by HPLC. The purity of this product is high, with a minimum purity of 98%.Formule :C16H19FN2O5Degré de pureté :Min. 95%Couleur et forme :Off-White To Yellow SolidMasse moléculaire :338.33 g/molGliclazide impurity F
CAS :Gliclazide is a sulfonylurea drug that is used to treat type 2 diabetes. The impurity F, which is an impurity standard, can be synthesized by reacting 1-chloro-2,6-difluoroaniline with sodium methoxide in methanol. It is also an API impurity found in the synthesis of gliclazide and can be custom synthesized for research and development purposes. Gliclazide impurity F has a CAS number of 1076198-18-9 and the molecular formula C8H4ClF3NOS. This product has a purity of >99% and is classified as synthetic. It has been shown to have pharmacopoeia activity and can also be used for niche applications such as drug development.Formule :C15H21N3O3SDegré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :323.41 g/molAztreonam impurity D
CAS :Aztreonam impurity D is a metabolite of aztreonam. Aztreonam impurity D is an impurity standard for the pharmacopoeia and API industry, as well as for drug development and research. It has been shown that this compound inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Aztreonam impurity D also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.Formule :C13H17N5O5SDegré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :355.37 g/mol(RS)-Di-(2-methoxyethyl) 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate
CAS :(RS)-Di-(2-methoxyethyl) 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate is an impurity standard for the API (Active Pharmaceutical Ingredient) Impurity Standard. It may be used as a reference compound in HPLC analyses of analytical samples. This compound has been evaluated by the National Institute of Standards and Technology (NIST) to be a niche HPLC standard. It is also a metabolite of the drug product Metaxalone.Formule :C21H26N2O8Degré de pureté :Min. 95%Couleur et forme :Slightly Yellow PowderMasse moléculaire :434.44 g/mol2,6-Dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid isopropyl 2-methoxyethyl ester
CAS :Nimodipine is a calcium channel blocker that is used to treat subarachnoid hemorrhage and aneurysms. It is also used as a neuroprotective agent in the treatment of stroke, intracranial hypertension, and cerebral vasospasm. Nimodipine acts by blocking voltage-sensitive L-type calcium channels in the cell membrane, which leads to a decrease in intracellular calcium levels. This results in decreased synthesis of nitric oxide and vasodilation, which reduces blood pressure and improves circulation to the brain. Nimodipine is administered intravenously or orally for the treatment of aneurysms or subarachnoid hemorrhage. It may be given as an infusion or as tablets for prevention of stroke and other neurological disorders.Formule :C21H24N2O7Degré de pureté :Min. 95%Couleur et forme :Slightly Yellow PowderMasse moléculaire :416.42 g/molAtorvastatin lactam sodium salt impurity
CAS :Atorvastatin is a drug used for the treatment of hypercholesterolemia and cardiovascular diseases. Atorvastatin lactam, which is an impurity formed during the synthesis of atorvastatin, has been shown to inhibit cholesterol biosynthesis in a rat model. The in vivo metabolism of atorvastatin lactam was studied by HPLC-MS/MS and was found to be identical to that of the parent molecule. This impurity may be useful as a research and development or custom synthesis product, or as an impurity standard for HPLC analysis.
Formule :C33H34FN2NaO6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :596.62 g/molN-Methylnitroacetamide
CAS :N-Methylnitroacetamide is a pyridinium salt used as an additive in pharmaceutical preparations. It is also a drug substance that is used for oral dosage, and has been shown to be active in methylene chloride and organic solvents. This chemical has been found to have a number of impurities, including acidic compounds and organic solvents, which can cause it to degrade over time. The use of this compound requires validation and kinetic studies to ensure it meets the quality standards for its intended use.Formule :C3H6N2O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :118.09 g/molSildenafil N-Oxide
CAS :Sildenafil N-Oxide is a solvate, hydrate, and prodrug of sildenafil citrate. It is used for the treatment of erectile dysfunction or pulmonary hypertension. Sildenafil N-Oxide is an oral drug that is converted to its active form, sildenafil, in the liver by CYP3A4. Sildenafil N-Oxide's effects on human erection are thought to be due to its ability to block phosphodiesterase type 5 (PDE5), which increases the levels of cGMP in smooth muscle cells and causes relaxation of the corpus cavernosum. This leads to increased blood flow into the penis and an erection.Formule :C22H30N6O5SDegré de pureté :Min. 95%Masse moléculaire :490.58 g/molSitagliptin Diamide impurity
Sitagliptin Diamide Impurity is a drug product that is a white crystalline powder. It has been developed as an analytical standard for the impurity Sitagliptin Diamide. The impurity is a metabolite of sitagliptin, which is an oral antidiabetic drug used to treat type 2 diabetes. Sitagliptin Diamide Impurity can be used as a pharmaceutical intermediate and in research and development.Formule :C20H19F6N5O3Degré de pureté :Min. 95%Masse moléculaire :491.39 g/molDifluoro atorvastatin
CAS :Difluoro atorvastatin is a filtrate of atorvastatin, which is a cholesterol-lowering drug. It is synthesized by reacting butyric acid with atorvastatin in an organic solvent. The reaction solution was filtered to remove impurities and then purified by liquid chromatography. The product was characterized by diffraction and LC-MS analysis. Difluoro atorvastatin has a high purity and is suitable for further use in the preparation of pharmaceuticals.
Formule :C33H34F2N2O5Degré de pureté :Min. 95%Masse moléculaire :576.63 g/mol3-o-Methyl colterol
CAS :3-o-Methyl colterol is a synthetic drug product. It is an impurity found in the natural product colterol, which is used as a drug for the treatment of high blood pressure. 3-o-Methyl colterol can be prepared by reacting its dihydropyridine with methyl iodide and hydrochloric acid. The compound has been found to be an impurity in colterol, which prevents its use as a therapeutic agent. 3-o-Methyl colterol has been studied in Metabolism studies and has shown no toxic effects on animals or humans.Formule :C13H21NO3Degré de pureté :Min. 95%Masse moléculaire :239.31 g/molMethyl 4-hydroxy-2-methyl-(2H)-1,2-benzothiazine-3-carboxylate-1,1-dioxide
CAS :Methyl 4-hydroxy-2-methyl-(2H)-1,2-benzothiazine-3-carboxylate-1,1-dioxide is a centrosymmetric molecule with an aspergillus flavus conformation. It is an acetanilide derivative that has been shown to be an effective antioxidant and medicine for the treatment of cancer. This product is also used in the production of hydrogen bonds and linkers in organic synthesis. The yields are high and it can be oriented during irradiation.Formule :C11H11NO5SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :269.28 g/mol1,2,3,4-Tetrahydroisoquinoline-4,6,7-triol
CAS :1,2,3,4-Tetrahydroisoquinoline-4,6,7-triol is an analytical standard that has been synthesized using a custom synthesis. It is used to determine the purity of the drug product and as an impurity in the synthesis of other compounds. 1,2,3,4-Tetrahydroisoquinoline-4,6,7-triol is a product of natural origin and is found in plants such as licorice roots. This compound can be used for drug development research and development purposes.Formule :C9H11NO3Degré de pureté :Min. 95%Masse moléculaire :181.19 g/molChlorhexidine digluconate impurity K dihydrochloride
CAS :Chlorhexidine digluconate impurity K dihydrochloride is a drug product that is an analytical standard. It is a natural metabolite of chlorhexidine digluconate, which is a synthetic compound. Chlorhexidine digluconate impurity K dihydrochloride has been shown to have anti-inflammatory properties and to inhibit the production of prostaglandins in animal studies. The pharmacopoeia designation for this drug product is USP/NF.Formule :C22H29Cl2N9ODegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :506.43 g/molPentixafor
CAS :When bound with 68Ga is used in PET/CT as a diagnostic in multiple myeloma detection
Formule :C60H80N14O14Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :1,221.4 g/mol2'-Deoxy-2',2'-difluorocytidine 5'-triphosphate sodium, 10 mM aqueous solution
CAS :2'-Deoxy-2',2'-difluorocytidine 5'-triphosphate sodium, 10 mM aqueous solution is an analytical standard that is used in metabolism studies and as an impurity in some pharmaceuticals. This chemical is also used to develop drugs, such as antiviral and anti-inflammatory agents. 2'-Deoxy-2',2'-difluorocytidine 5'-triphosphate sodium, 10 mM aqueous solution has a CAS number of 1440537-37-0 and the molecular weight of 463.88 g/mol. This compound is soluble in water, ethanol, DMSO, acetone and acetonitrile at room temperature. The purity for this compound is > 99%.
Formule :C9H14F2N3O13P3•NaxDegré de pureté :Min. 95%Couleur et forme :Clear LiquidMasse moléculaire :503.14 g/molRemdesivir nucleoside monophosphate
CAS :Remdesivir is a nucleoside monophosphate that inhibits the HIV-1 reverse transcriptase and HIV-1 protease. This drug is used to treat human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS). Remdesivir blocks the viral life cycle by preventing the production of new viruses. It also has an affinity for polymerase and phosphatase, which are enzymes necessary for viral replication. Remdesivir is uncharged, so it can be taken orally.
Remdesivir does not work against all strains of HIV, but it does inhibit some strains more than others.Formule :C12H14N5O7PDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :371.24 g/molL-138,037
CAS :Please enquire for more information about L-138,037 including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C28H34N4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :426.6 g/mol2-[[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]thio]-1H-benzimidazole
CAS :Rabeprazole is a proton pump inhibitor that is used to treat acid-related disorders such as gastroesophageal reflux disease and peptic ulcers. Rabeprazole inhibits the production of gastric acid by blocking the hydrogen/potassium ATPase that is found in the parietal cells of the stomach. The main mechanism of action for rabeprazole is competitive inhibition of the proton pump, which leads to decreased gastric acid secretion. Rabeprazole can be administered orally or intravenously, with a half-life of about 2 hours. It has been shown to have an effect on human liver cytochrome P450s, but does not affect the activity of recombinant cytochrome P450 3A4 (CYP3A4). In clinical studies, rabeprazole was shown to have no adverse effects on CYP3A4 activity and may even increase it slightly.Formule :C18H21N3O2SDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :343.44 g/mol2,2-Bis(N-(a,a,a-trifluoro-m-tolyl)antranililoxi)diethylether
CAS :2,2-Bis(N-(a,a,a-trifluoro-m-tolyl)antranililoxi)diethylether is a natural compound that is an impurity in the drug 2,2-Bis(N-(a,a,a-trifluoro-m-tolyl)antranilic acid). It has been used as an analytical reference material and as a standard for HPLC. The synthesis of this compound has not been reported. It has been shown to be metabolized by hydrolysis to form 2-(4'-aminophenyl)-3H-[1]benzopyran and benzeneacetic acid. 2,2-Bis(N-(a,a,a-trifluoro-m-tolyl)antranililoxi)diethylether is also known as bis(4'-aminophenyl)-3H-[1Formule :C32H26F6N2O5Degré de pureté :Min. 95%Couleur et forme :Slightly Yellow Yellow Clear LiquidMasse moléculaire :632.55 g/molBiotin impurity E
Biotin impurity E is a metabolite of biotin that is produced by the metabolism of biotin in humans. It can be detected in urine, saliva, and blood. Biotin impurity E has been shown to be naturally occurring and is a metabolite of biotin found as an impurity in pharmaceutical products. The purity of this drug product was determined to be 98% by HPLC analysis with a detection limit of 0.1%.
Formule :C34H44N4O6S2Degré de pureté :Min. 95%Masse moléculaire :668.9 g/mol2-Acetamido-9-[[2-(acetyloxy)ethoxy]methyl]-6,9-dihydro-1H-purin-6-one
CAS :2-Acetamido-9-[2-(acetyloxy)ethoxy]methyl-6,9-dihydro-1H-purin-6-one (ademetionine) is a prodrug that is metabolized in the liver to form ademetionine. Ademetionine is a potent inhibitor of guanosine deaminase, which is an enzyme that breaks down guanosine into guanine and ammonia. Ademetionine has shown efficacy in cancer treatment and may also be used to treat tuberculosis. The metabolism of this drug takes place in the liver, where it undergoes oxidation by cytochrome P450 enzymes to form the active metabolite ademetionine. Metabolism of this drug can be inhibited by drugs such as trifluoromethanesulfonic acid (TFMS), which are used for the treatment of malaria. TFMS inhibits the formation of ademetionine but does not affect the formationFormule :C12H15N5O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :309.28 g/mol5-(2-Ethoxyphenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
CAS :Sildenafil is a selective PDE-5 inhibitor that is used in the treatment of erectile dysfunction. It has been shown to have anticancer activity in vitro and in vivo. Sildenafil inhibits the activity of cyclic guanosine monophosphate (cGMP) phosphodiesterase type 5 (PDE-5), which is found in the corpus cavernosum of the penis and inhibits cGMP degradation, leading to vasodilation and increased blood flow. Sildenafil has been shown to inhibit cancer cell proliferation by blocking the synthesis of both DNA and protein, as well as inhibiting the expression of genes encoding for anti-apoptotic proteins. Sildenafil binds to PDE-5 with high affinity, but does not bind to other PDEs or ion channels at therapeutic concentrations.Formule :C17H20N4O2Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :312.37 g/mol5-(2-Cyclopropyl-1-(3-fluorophenyl)-2-oxoethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate
CAS :5-(2-Cyclopropyl-1-(3-fluorophenyl)-2-oxoethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate is a substance that is used as a reference in high performance liquid chromatography (HPLC) methods. It is used to validate the method in accordance with the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH). The substance is also known as prasugrel hydrochloride and it is used as an antiplatelet agent.Formule :C20H20FNO3SDegré de pureté :Min. 95 Area-%Couleur et forme :Slightly Yellow PowderMasse moléculaire :373.44 g/molBisoprolol impurity K
CAS :Bisoprolol impurity K is a drug product that is an analytical standard used for the detection and identification of bisoprolol in pharmaceutical products. It is a synthetic impurity with CAS No. 864544-37-6 that does not have any pharmacological activity. Bisoprolol impurity K is a high purity HPLC standard that can be used to develop analytical methods for the determination of bisoprolol in pharmaceutical products.
Formule :C18H29NO5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :339.43 g/molN-tert-butyl-N-(((S)-3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide
CAS :N-tert-butyl-N-(((S)-3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide (CAS 1215006-11, API impurity) is a synthetic compound from the drug development process. This impurity has been identified in the natural product and is not an active ingredient. It is found as a Metabolite in the pharmacopoeia and analytical methods. This substance is used for research and development of drugs, such as for standardizing HPLC.Formule :C20H28FN3O4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :393.45 g/molRifaximin EP Impurity D
Rifaximin EP Impurity D is an analytical impurity that has been identified as a metabolite of the drug Rifaximin. It is a white crystalline powder with no characteristic odor. This product can be used as an HPLC standard, niche compound, or pharmacopoeia impurity. It can also be custom synthesized to meet the needs of your research and development project.
Degré de pureté :Min. 95%N,N',N''-Tris(4-chlorobenzylideneimino)guanidine hydrochloride
CAS :N,N',N''-Tris(4-chlorobenzylideneimino)guanidine hydrochloride is an analytical standard used to determine the purity of a drug product. It is also used as a pharmacopoeia standard and in research and development. N,N',N''-Tris(4-chlorobenzylideneimino)guanidine hydrochloride is synthesized from 4-chlorobenzaldehyde and 1,2,3-triazole. It has been shown that this chemical can be metabolized by CYP1A2, CYP2D6, CYP3A4, and CYP3A5 enzyme systems. This chemical has not been found to have any impurities.Formule :C22H17Cl3N6•(HCl)xDegré de pureté :Min. 95%Couleur et forme :White to off-white solid.Masse moléculaire :471.77 g/molN,N'-Bis(4-chlorobenzylidene)hydrazine
CAS :N,N'-Bis(4-chlorobenzylidene)hydrazine is an organic nitrogen compound that is used as a reagent in organic chemistry. It can be used to synthesize hydrazones, toluenes, and carbonyls. This reagent also has the ability to catalyze olefinations. N,N'-Bis(4-chlorobenzylidene)hydrazine can be crystallized from its aryldiazomethanes.
Formule :C14H10Cl2N2Degré de pureté :Min. 95%Masse moléculaire :277.15 g/mol(S)-(+)-4-Phenyl-2-oxazolidinone
CAS :(S)-(+)-4-Phenyl-2-oxazolidinone is a synthetic, white to off-white solid that is soluble in water and ethanol. It is used as an analytical standard for the determination of the drug product and impurities during development and manufacture. The CAS number for (S)-(+)-4-Phenyl-2-oxazolidinone is 99395-88-7.Formule :C9H9NO2Degré de pureté :Min. 95%Masse moléculaire :163.17 g/molN4-Acetyl sulfadoxine
CAS :N4-Acetyl sulfadoxine is a drug that is used to treat urinary tract infections in women and children. It is also used to treat bacterial infections of the skin, lungs, and joints. N4-Acetyl sulfadoxine may be effective against prostatitis caused by E. coli or Mycoplasma pneumoniae by inhibiting the production of prostaglandins. This drug works by binding to dihydropteroate synthase, which prevents folic acid from being incorporated into the bacterial cell wall, thereby inhibiting bacterial growth.Formule :C14H16N4O5SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :352.37 g/mol11-Piperazin-1-yl-dibenzo[b,f][1,4]thiazepine
CAS :11-Piperazin-1-yl-dibenzo[b,f][1,4]thiazepine is a drug used to treat schizophrenia and bipolar disorder. It is a member of the thiazepine class of antipsychotics that blocks dopamine receptors in the brain. 11-Piperazin-1-yl-dibenzo[b,f][1,4]thiazepine has been shown to be effective for treatment trials and toxicity studies in animals. This drug has also been shown to have an anti-inflammatory effect on cytokines such as il-10. The drug interacts with other drugs by inhibiting the activity of certain enzymes that metabolize it so it can be eliminated from the body more quickly. The elimination half life for this drug is about 6 hours. 11-Piperazin-1-yl-dibenzo[b,f][1,4]thiazepine binds to specific receptors in the brain which
Formule :C17H17N3SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :295.4 g/mol(S)-6-(Ethyl(2-(thiophen-2-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride
CAS :(S)-6-(Ethyl(2-(thiophen-2-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride is a synthetic compound that has been designed for use as an impurity standard in the validation of analytical methods. It is a custom synthesis product and is not commercially available. It is a white crystalline solid with a melting point of 170°C and its molecular formula is C14H12N2O3S. (S)-6-(Ethyl(2-(thiophen-2-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride has been shown to have no biological activity in rats.Formule :C18H24ClNOSDegré de pureté :Min. 95%Masse moléculaire :337.9 g/molAll-trans-retinol-d5
CAS :Produit contrôléAll-trans-retinol-d5 is a supplement that is used to protect the brain from oxidative damage and to help maintain healthy skin. It is an antioxidant that prevents free radicals from damaging cells and helps maintain the structural integrity of cell membranes. All-trans-retinol-d5 can be found in high concentrations in animal tissues, such as liver, lung, kidney, heart, brain, and eye. It can also be found in human urine. The presence of all-trans-retinol-d5 in urine has been correlated with neuroprotective effects. Retinol levels have been shown to be higher in children who are less obese than those who are obese or overweight. All-trans retinol has been shown to inhibit cancer cell proliferation and induce apoptosis by inhibiting protein synthesis at the level of transcription.
Formule :C20H25D5ODegré de pureté :(%) Min. 80%Couleur et forme :Clear Viscous LiquidMasse moléculaire :291.48 g/molN-(1-Oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-D-valine
CAS :N-(1-Oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-D-valine is a potent and selective inhibitor of the enzyme lipase. It prevents the hydrolysis of triglycerides by competitively binding to the active site of lipase. This inhibition leads to an increase in serum levels of triglycerides, which are associated with cardiometabolic risk factors. Novartis developed this drug as an alternative to sacubitril/valsartan, which is used for the treatment of heart failure. The pharmacokinetics and pharmacodynamics of this drug are similar to those of sacubitril/valsartan. N-(1-Oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-D-Formule :C24H29N5O3Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :435.52 g/molrac-2-Cyano-2-phenylbutanamide
CAS :Rac-2-cyano-2-phenylbutanamide is a synthetic molecule that is used as a growth regulator. It has been shown to be toxic to the arthropod Mollusca, with an LD50 of 1.6 µg/cm² (milligrams per square centimeter). Rac-2-cyano-2-phenylbutanamide also inhibits the growth of organisms such as Anisopliae and Metarhizium, and has been shown to have an asymmetric effect on tissue culture cells. Rac-2-cyano-2-phenylbutanamide is chemically related to the antibiotic subtilin, which belongs to the class of aminoglycoside antibiotics. Rac-2-cyano-2-phenylbutanamide may inhibit bacterial protein synthesis by binding to ribosomes and blocking the attachment of aminoacyl tRNA molecules during translation. This compound also inhibits DNA replication in bacteria by preventing DNAFormule :C11H12N2ODegré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :188.23 g/molN-Acetyldesloratadine
CAS :N-Acetyldesloratadine is a second generation antihistamine that has high affinity for histamine H1 receptors. It is an orally active drug that is used to treat allergic rhinitis, chronic idiopathic urticaria, and pruritus. N-Acetyldesloratadine has been shown to inhibit platelet aggregation in vitro and in vivo. This activity may be due to the drug's ability to bind with high affinity to histamine receptor sites on the membranes of platelets, thereby inhibiting the binding of adenosine diphosphate (ADP) to its receptor site. N-Acetyldesloratadine also inhibits the release of serotonin from mast cells and basophils in vitro.Formule :C21H21ClN2ODegré de pureté :Min. 95%Masse moléculaire :352.9 g/molN-Desmethyl cyamemazine maleate
CAS :Cyamemazine is an antipsychotic drug that has been used for the treatment of schizophrenia and other psychotic disorders. N-Desmethyl cyamemazine maleate, a metabolite of cyamemazine, has been shown to have neuroprotective effects in vitro.Formule :C18H19N3S·C4H4O4Degré de pureté :Min. 95%Masse moléculaire :425.5 g/molMolnupiravir Impurity 8
CAS :Produit contrôléMolnupiravir Impurity 8 is an impurity of molnupiravir, a drug product. It is a synthetic chemical compound that has not been found in nature. Molnupiravir Impurity 8 is the result of metabolism studies on the API (active pharmaceutical ingredient) and was observed to be more abundant than other impurities. Molnupiravir Impurity 8 is a white crystalline solid with CAS number 2492423-30-8. It is soluble in water, ethanol, acetone, and chloroform. The purity of this impurity is 99%.Formule :C13H19N3O7Degré de pureté :Min. 95%Masse moléculaire :329.31 g/mol3-(Dimethylamino)-1-(3-thienyl)propan-1-ol
CAS :3-(Dimethylamino)-1-(3-thienyl)propan-1-ol (DMAT) is an impurity that was identified in a drug product and that is not found in the natural form. DMAT is an intermediate of the synthesis of DMH, which is used as a research and development tool. DMAT has been shown to be metabolized by cytochrome P450 enzymes and other oxidative reactions, such as oxidation by cytochrome P450 enzymes or conjugation with glucuronic acid. DMAT also binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.
Formule :C9H15NOSDegré de pureté :Min. 95%Couleur et forme :White to yellow solid.Masse moléculaire :185.29 g/mol3-Oxo-1,2-benzisothiazole-2(3H)-acetic acid ethyl ester 1,1-dioxide
CAS :3-Oxo-1,2-benzisothiazole-2(3H)-acetic acid ethyl ester 1,1-dioxide is an impurity in the synthesis of a drug. It is not active and has no known therapeutic value. 3-Oxo-1,2-benzisothiazole-2(3H)-acetic acid ethyl ester 1,1-dioxide is used as a reference standard for HPLC and has been shown to be metabolized by cytochrome P450 enzymes.Formule :C11H11NO5SDegré de pureté :Min. 95%Couleur et forme :White to off-white solid.Masse moléculaire :269.27 g/mol2-(4-Butylphenyl)propionic acid, racemic
CAS :2-(4-Butylphenyl)propionic acid (p-butylhydratropic acid) is a known impurity of ibuprofen (Ibuprofen impurity B) which derives from an impurity present in the isobutylbenzene starting material and 2-(4-butylphenyl)propionic acid. p-Butylhydratropic acid is therefore used as a reference analytical standard.Formule :C13H18O2Degré de pureté :Min. 95%Couleur et forme :Colorless PowderMasse moléculaire :206.28 g/molPantoprazole sodium hydrate - Mixture of impurities D and F
CAS :Pantoprazole sodium hydrate is a custom synthesis that is used as a drug product. The CAS number for this compound is 624742-53-6. This compound has the following impurities: D and F. Pantoprazole sodium hydrate has been shown to be metabolized in vitro by human liver microsomes to its metabolites, including the following: (1) pantoprazol acid, (2) 4-hydroxypantoprazol acid, (3) 4-hydroxyisoxazole acid, and (4) 5-(4-hydroxyphenyl)-2H-1,2-benzoxazin-3(4H)-one. The metabolite 4-hydroxypantoprazol acid has been found to be pharmacologically active in animal models of gastric ulceration and healing.Formule :C17H17F2N3O4SDegré de pureté :Min. 95%Couleur et forme :Off-white to yellow powder.Masse moléculaire :397.4 g/molCisplatin impurity A
CAS :Cisplatin impurity A is a platinum-based chemotherapeutic agent that binds to DNA and inhibits the synthesis of cellular proteins. Cisplatin impurity A has been shown to inhibit the growth of cancer cells in vitro and in vivo. This compound also inhibits the production of epidermal growth factor, which may be due to its ability to bind dna at tetrazolium dye adducts. The coordination geometry of cisplatin impurity A is octahedral with two axial bidentate chelating ligands, which allows it to bind both DNA and tubule cells.Formule :(NH3)2Cl2PtCouleur et forme :PowderMasse moléculaire :300.05 g/molLisdexamfetamine dimesylate impurity C
Lisdexamfetamine dimesylate impurity C is a drug product that is an analytical standard. It is a synthetic impurity found in the drug Lisdexamfetamine Dimesylate, which is used for the treatment of ADHD and narcolepsy. Lisdexamfetamine Dimesylate Impurity C has been shown to be metabolized through oxidation by cytochrome P450 enzymes and conjugation with glucuronic acid. The impurity has been shown to have no effect on the pharmacological activity of the parent compound.
Degré de pureté :Min. 95%5-Benzoyl-7-bromo-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic
CAS :5-Benzoyl-7-bromo-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic is a drug product that is used for the research and development of drugs. It is manufactured synthetically. This compound has been shown to be metabolized in rats and humans. Studies have also shown that this compound may be an impurity in other drugs. The use of 5-Benzoyl-7-bromo-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic can be found in the USP/NF as a HPLC standard or as an analytical reference standard.Formule :C15H12BrO3NDegré de pureté :Min. 95%Masse moléculaire :334.16 g/molMontelukast ketone impurity
CAS :The impurity (2,6-dichlorobenzaldehyde) is a metabolite of montelukast. It is an analytical impurity that has been quantified in the drug product and has also been found to be present in the synthetic process. The impurity standard was developed using HPLC. It can be used as a high purity reference material for pharmacopoeia and custom synthesis.Formule :C29H26ClNO2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :455.97 g/mol(S,E)-N-(1-(3-Methylbut-1-enylamino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
CAS :R-N-(1-(3-methylbut-1-enyl)-1-oxo-3-phenylpropan-2-yl) pyrazine-2-carboxamide is a drug product that is used for the treatment of bacterial infections. The compound is an impurity in the synthesis of other compounds and is also used as an analytical standard. It is synthesized from commercially available starting materials and through custom synthesis. R-N-(1-(3-methylbut-1-enyl)-1--oxo--3--phenylpropan--2--yl)pyrazine--2--carboxamide has been shown to be metabolized by CYP450 enzymes, which are responsible for the metabolism of many drugs. R-(1-(3Methylbut 1Enylamino)-1Oxo 3Phenylpropan 2Yl)Pyrazine 2Carboxamide has not been evaluated as a drug product and therefore does notFormule :C19H22N4O2Degré de pureté :Min. 95%Masse moléculaire :338.4 g/moltrans-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine
CAS :The compound is a natural product and its structure is similar to that of the neurotransmitter dopamine. The compound has been used in pharmacological studies as a tool for understanding the neurotoxicity of dopamine and other drugs. This drug has also been used to investigate the level of dopamine receptor occupancy by various dopaminergic drugs.Formule :C13H18FNODegré de pureté :Min. 95%Masse moléculaire :223.29 g/mol4-[(2,4-Dihydroxy-3,3-dimethylbutanoyl)amino]-butanoic acid
CAS :4-[(2,4-Dihydroxy-3,3-dimethylbutanoyl)amino]-butanoic acid is a white to off-white solid that is soluble in water. It is used as an impurity standard for drug product and as a custom synthesis for research and development. This compound is metabolized by oxidation to form an alcohol and carboxylic acid. The oxidation products are excreted in the urine. 4-[(2,4-Dihydroxy-3,3-dimethylbutanoyl)amino]-butanoic acid has been used for metabolism studies with human liver microsomes.Formule :C20H38CaN2O11Degré de pureté :Min. 95%Masse moléculaire :522.6 g/molSimvastatin hydroxy acid ethyl ester
CAS :Simvastatin hydroxy acid ethyl ester is a solvated form of simvastatin, an investigational drug for the treatment of dyslipidemia. The ammonium salt was prepared by alcoholysis with ethanol. The elution process was carried out using an acetonitrile-water mixture and chromatography on silica gel. Preparation methods were investigated to determine the best preparative procedure that would yield pure material. This compound has been investigated as a possible therapeutic agent for the treatment of midbody diseases such as familial amyloidotic polyneuropathy and Alzheimer's disease.Formule :C27H44O6Degré de pureté :Min. 95%Couleur et forme :Colourless To Pale Yellow LiquidMasse moléculaire :464.63 g/molTyrosol glucuronide
CAS :Tyrosol is a phenolic compound found in olive oil and other plant sources. It has been shown to have antioxidant, anti-inflammatory, and anti-cancer activities. Tyrosol glucuronide is the main form of tyrosol found in urine samples. The absorption process of tyrosols is due to their uptake by the liver cells, where they are converted into fatty acids and then conjugated with glucuronic acid. Tyrosols are also metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Studies have shown that tyrosols can help lower blood pressure and improve insulin resistance in women.Formule :C14H18O8Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :314.29 g/mol3-(4-(4-Morpholinyl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one
CAS :3-(4-(4-Morpholinyl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one is an impurity in the drug development process. It is used as a standard for HPLC testing and a synthetic intermediate. It has been shown to have niche use in the pharmaceutical industry. 3-(4-(4-Morpholinyl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one has been found to be metabolized through oxidation and reduction reactions, leading to the formation of metabolites such as 2,6-dihydroxypyridine (DHP). Further metabolism studies are required for this substance.
Formule :C14H18N2O4Degré de pureté :Min. 95%Couleur et forme :White to off-white solid.Masse moléculaire :278.3 g/mol5,6-Dichloro-1,4-dihydro-2-quinazolinamine
CAS :5,6-Dichloro-1,4-dihydro-2-quinazolinamine (5,6-DCQ) is a small molecule that has been used in vitro to study postnatal development. 5,6-DCQ binds to magnesium and forms a cation complex. This binding inhibits the activity of various enzymes such as phosphodiesterase and acetylcholinesterase. 5,6-DCQ also blocks the proliferation of cancer cells in vitro by inhibiting colony-stimulating factor and other proteins required for cell division. 5,6-DCQ has been shown to be safe in clinical trials and may be an effective treatment for cancer.Formule :C8H7Cl2N3Degré de pureté :Min. 95%Masse moléculaire :216.07 g/mol1b-(4-Fluorophenyl)hexahydro-β,7-dihydroxy-7-(1-methylethyl)-1a-phenyl-7a-[(phenylamino)carbonyl]-3H-oxireno[3,4]pyrrolo[2,1-b][1,3] oxazine-3-butanoic acid sodium
CAS :Fluoxetine is a selective serotonin reuptake inhibitor that is used to treat major depressive disorder, obsessive-compulsive disorder (OCD), bulimia nervosa, panic disorder, premenstrual dysphoric disorder (PMDD), and social anxiety disorder. It is also used as an appetite suppressant in some countries. Fluoxetine inhibits the neuronal uptake of serotonin by blocking the presynaptic transporter protein. The most common adverse effects are nausea, diarrhea, drowsiness, dry mouth, blurred vision and sexual dysfunction.Formule :C33H35FN2O7•NaDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :613.63 g/mol(R)-5-Hydroxymethyl tolterodine
CAS :(R)-5-Hydroxymethyl tolterodine is a prodrug that is metabolized by cytochrome P450 3A4 (CYP3A4) in the liver to its active form, tolterodine. This drug can be used as an alternative for gabapentin in the treatment of detrusor muscle overactivity associated with neurogenic bladder dysfunction. The pharmacokinetic properties of (R)-5-hydroxymethyl tolterodine are similar to those of gabapentin, including the elimination half-life and volume of distribution. However, unlike gabapentin, which has been shown to increase the glomerular filtration rate (GFR) and renal blood flow, there is no evidence that this drug has any effect on GFR or renal blood flow. There is also no evidence that (R)-5-hydroxymethyl tolterodine causes any symptoms that may be attributed toFormule :C22H31NO2Degré de pureté :Min. 98 Area-%Couleur et forme :Off-White PowderMasse moléculaire :341.49 g/mol3-[[[2-[(Diaminomethylene)amino]-4-thiazolyl]methyl]thio]propanimidamide hydrochloride
CAS :3-[[[2-[(Diaminomethylene)amino]-4-thiazolyl]methyl]thio]propanimidamide hydrochloride is a Custom synthesis, drug product, Metabolite, Synthetic, Drug development, Impurity standard, Metabolism studies, API impurity, Natural and pharmacopoeia. 3-[[[2-[(Diaminomethylene)amino]-4-thiazolyl]methyl]thio]propanimidamide hydrochloride has CAS No. 76833-47-1 and is a High purity.Formule :C8H14N6S2·HClDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :294.83 g/molN,N'-Bis[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-nitroethene-1,1-diamine
CAS :N,N'-Bis[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-nitroethene-1,1-diamine is a drug development impurity that has been shown to be an API impurity in the synthesis of gatifloxacin. N,N'-Bis[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-nitroethene-1,1-diamine is often used as a HPLC standard and in research and development. It may have some pharmacopoeia use as an analytical standard. The structural formula is: CAS No.: 72126-78-4 Molecular Formula: C14H18N3O6S Molecular Weight: 328.38 Purity (GC): 99.9Formule :C22H35N5O4S2Degré de pureté :Min. 95%Couleur et forme :Red PowderMasse moléculaire :497.68 g/molTacrolimus Impurity 6
CAS :Tacrolimus Impurity 6 is a product that is custom-synthesized by our company. It is a high purity, analytical standard used in the study of drug metabolism. This impurity can be found in the natural form and as a synthetic compound. It has been shown to act as an inhibitor of protein synthesis, which may be due to its inhibition of methionine synthase activity.Formule :C44H71NO13Degré de pureté :Min. 95%Masse moléculaire :822.03 g/mol2-(N-Methyl-propanamine)-3-(2-naphthyl) thiophene
CAS :2-(N-Methyl-propanamine)-3-(2-naphthyl) thiophene is a synthetic compound that has been used as an impurity standard for the drug product and API. It has also been used for the pharmacopoeia, research and development, and analytical purposes. This compound is a metabolite of erythromycin.Formule :C18H19NOSDegré de pureté :Min. 95%Couleur et forme :White To Pink Or Yellow SolidMasse moléculaire :297.42 g/mol
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