APIs pour la recherche et les impuretés

Please enquire for more information about 5-Amino-6-hydroxy-2-(propylthio)-4(3H)-pyrimidinone including the price, delivery time and more detailed product information at the technical inquiry form on this page

3-Hydroxy citalopram oxalate (3HCO) is a drug product that is used as an analytical standard and impurity standard. It is synthesized in the laboratory by reacting 3,4-dihydroxyphenylacetic acid with citalopram, followed by esterification with oxalic acid. The purity of the final product is typically >98%.

Please enquire for more information about 2-Amino-5-(2-bromoacetyl)benzonitrile hydrobromide including the price, delivery time and more detailed product information at the technical inquiry form on this page

9-Cis,13-cis-retinol 15-acetate is an impurity in drugs that are used to treat a variety of conditions including psoriasis, acne, and ichthyosis. It has been identified as an impurity in the drug product 9-cis, 13-cis retinoic acid (9CRA) through high performance liquid chromatography (HPLC). It has been found to be a metabolite of 9CRA and is not toxic.

N-Desmethyl-4-hydroxy tamoxifen β-D-glucuronide is a drug product that is used as an analytical reference for the identification and quantification of Metabolites in drug metabolism studies. It is synthesized from 4-hydroxytamoxifen, which has been shown to have antiestrogenic effects and inhibit the growth of estrogen receptor (ER)-positive breast cancer cells. N-Desmethyl-4-hydroxy tamoxifen β-D-glucuronide has been shown to be a metabolite of 4-hydroxytamoxifen. This impurity standard is available in both powder and liquid form with purity levels up to 99%. It can be custom synthesized upon request, with a lead time of 5 weeks.
NDA: N/A

PBDE 155 is an analog of PBDE, a kinase inhibitor that has shown potential as an anticancer agent. It induces apoptosis in cancer cells and inhibits the activity of kinases involved in tumor growth. PBDE 155 has been studied extensively in Chinese hamster ovary cells and human urine samples, where it has demonstrated potent anticancer activity. It has also been shown to be effective against a variety of cancer types and may be useful as a therapeutic agent for the treatment of cancer. Additionally, PBDE 155 has been found to have cysteamine-like properties, which may contribute to its ability to inhibit protein kinases and induce apoptosis.

2,2',3,3'-Tetrachlorobiphenyl is an inhibitor that has been shown to have anticancer properties. It inhibits the growth of tumor cells by blocking the activity of protein kinases, which are enzymes that regulate cell division and proliferation. This compound has been tested in Chinese hamster ovary cells and has been found to induce apoptosis in cancer cells. Additionally, 2,2',3,3'-Tetrachlorobiphenyl has analog inhibitors that have been tested in human urine samples and have shown potential as anticancer agents. These analogs inhibit cyclin-dependent kinases (CDKs), which play a crucial role in regulating the cell cycle. The inhibition of CDKs leads to the suppression of cancer cell growth and division, making this compound a promising candidate for future cancer treatments.

(-)-Nefopam is a medicinal compound that acts as an inhibitor of kinases, which are enzymes involved in many cellular processes. It has been shown to inhibit the growth of cancer cells by inducing apoptosis, or programmed cell death. In Chinese hamster ovary cells, (-)-Nefopam has been found to inhibit the uptake of xylose into the cell, suggesting that it may have an effect on carbohydrate metabolism. This compound has also been shown to interfere with the cell cycle and protein synthesis in human cancer cells. Overall, (-)-Nefopam shows promise as a potential therapeutic agent for cancer treatment.

Please enquire for more information about 16α-Methyl clobetasone butyrate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Apremilast is a drug product that belongs to the class of drugs called phosphodiesterase 4 inhibitors. It acts by inhibiting the enzyme phosphodiesterase 4 (PDE4) and therefore blocks the degradation of specific signaling molecules, such as cyclic adenosine monophosphate (cAMP). Apremilast has been shown to have anti-inflammatory properties in preclinical studies and is being developed for the treatment of inflammatory diseases, including rheumatoid arthritis. Apremilast is not active against gram-positive bacteria or some other types of bacteria. Apremilast has been shown to have a low potential for drug interactions with other drugs metabolized by cytochrome P450 enzymes.

Tirofiban impurity 8 is an analytical standard for HPLC. It is a research-grade, high purity, impurity standard for the drug product. Tirofiban impurity 8 is a metabolite of tirofiban that has been shown to be pharmacologically active in animal models and in vitro. Tirofiban impurity 8 has a natural or synthetic origin and its CAS number is 2250244-25-6.

Please enquire for more information about 7-Hydroxydibenz[b,f][1,4]oxazepin-11(10H)-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

Gemcitabine diphosphate triethylamine salt is an inhibitor that has been shown to be effective in the treatment of various forms of cancer. It works by inhibiting the activity of kinases, which are enzymes involved in the regulation of cell growth and division. Gemcitabine diphosphate triethylamine salt is a prodrug that is converted to its active form, gemcitabine, in vivo. This drug has been shown to inhibit the uptake of xylose by cancer cells, leading to decreased protein synthesis and induction of apoptosis. In addition, it has been found to be effective against human and Chinese medicinal tumor cells. Gemcitabine diphosphate triethylamine salt is a promising treatment option for patients with cancer who have not responded well to traditional chemotherapy or radiation therapy.

Please enquire for more information about 5-Hydroxydeferasirox including the price, delivery time and more detailed product information at the technical inquiry form on this page

Phenproxide is an analog of testosterone that has been used traditionally in Chinese medicine to treat tumors. It has been found to induce apoptosis in cancer cells by inhibiting kinases, which are enzymes that regulate cellular processes such as cell division and growth. Phenproxide has also been shown to inhibit the activity of somatostatin, a hormone that regulates the release of other hormones. This inhibition may contribute to its anti-cancer properties. In addition, Phenproxide has been shown to have an effect on hyaluronan metabolism, a substance involved in tissue repair and inflammation. It is excreted in urine and may be used as a potential biomarker for cancer diagnosis or monitoring.

Tilnoprofen arbamel is a synthetic drug with antipyretic and analgesic properties, which is made in the laboratory. It is a metabolite of tilnoprofen that has been synthesized to meet the pharmacopoeia standards for purity. Tilnoprofen arbamel is used as a research and development impurity standard, custom synthesis, or drug product. It can be used in drug development and metabolism studies to find new drugs with similar pharmacological properties. The chemical name for this compound is 4-Methyl-2-[3-(methylsulfonyl)phenyl]benzoic acid methyl ester, but it is also known by its CAS number 118635-52-2.

CAS No. 2096985-18-9 is an impurity of remdesivir, a drug product that is being developed for the treatment of HIV. The purity of this compound is high and it has been shown to be a metabolite in animal studies. Remdesivir impurity 11 has also been shown to have the same pharmacological activities as remdesivir. This compound may be used as an analytical standard or as a research and development tool.