APIs pour la recherche et les impuretés

O-Desethyl Dapagliflozin is a white powder that is a synthetic drug product. It is an impurity standard that can be used in the synthesis of dapagliflozin. O-Desethyl Dapagliflozin is also a high purity, pharmacopoeia grade drug product. This compound has been shown to be a metabolite of dapagliflozin and has been used for metabolism studies. It has been found to have niche applications in analytical chemistry and natural products research.

This product is an organic compound that has a molecular formula of C6H7N3O2. It is a white solid with a melting point of 76.5 °C and an elution time of 7 minutes (range, 1-10 minutes). The detection method is based on the color change from yellow to blue in the presence of dimethylformamide (DMF). This product is used as a solvent for various chemical reactions and can be used in the synthesis of other products. 3-(Formylamino)-1H-pyrazole-4-carboxamide is used in analytical chemistry to determine substances such as pH, ionic strength, and concentration. In addition, this product can be used to quantify substances such as drugs or pharmaceuticals.

Aceclofenac ethyl ester is a prodrug of diclofenac. It is a non-steroidal anti-inflammatory drug that alleviates the symptoms of pain, stiffness, and swelling. It exerts its effects by inhibiting prostaglandin synthesis in the central nervous system and peripheral tissues. Aceclofenac ethyl ester has minimal systemic absorption when administered orally, which reduces the risk of side effects such as stomach upset and kidney damage. The pharmacopoeia provides an efficient method for preparing this compound by reacting diclofenac with magnesium stearate in a solvent containing an organic amine or alcohol at temperatures below 50°C (122°F). Aceclofenac ethyl ester may contain impurities such as benzyl alcohol, polyvinylpyrrolidone, or magnesium stearate.

3,4-Diphenylmethylidene luteolin is a synthetic compound with pharmacological activity. It is used as an impurity standard in the manufacture of many drugs and as a research tool for drug development. 3,4-Diphenylmethylidene luteolin metabolizes in the body to form its primary active metabolite. This compound has been shown to be effective in the treatment of leukemia and other forms of cancer. 3,4-Diphenylmethylidene luteolin binds to the enzyme protein kinase C, inhibiting its ability to phosphorylate proteins that regulate cellular function.

Naltrexone Impurity G is a synthetic impurity found in naltrexone. It is used as an impurity standard and can be custom synthesized to meet the needs of researchers, developers, and manufacturers of drug products. Naltrexone Impurity G is a metabolite that has been shown to have pharmacological effects similar to those of naltrexone. It is used in metabolism studies. Naltrexone Impurity G has a purity level of 99% or higher and can be ordered as a methanol solution or powder.

Diornithine is a medicinal compound that has been identified as an analog of ornithine, a non-essential amino acid found in human urine. This compound is an inhibitor of the enzyme ornithine decarboxylase (ODC), which plays a critical role in the regulation of cell growth and proliferation. Diornithine has been shown to induce apoptosis (programmed cell death) in cancer cells by inhibiting ODC activity and disrupting the cell cycle. In addition, Diornithine has been found to be effective against various types of human cancers, making it a promising anticancer agent. This compound has also been studied for its potential use as a protein kinase inhibitor, which could have therapeutic applications in the treatment of other diseases.

Heptamethylcyclotetrasiloxane is a medicinal compound that has been found to have anticancer properties. It acts as an inhibitor of kinases, which are proteins that play a key role in cancer cell growth and proliferation. Heptamethylcyclotetrasiloxane has been shown to induce apoptosis (programmed cell death) in cancer cells, making it a potential treatment for various types of tumors. This compound is an analog of other kinase inhibitors and has been tested in both Chinese and human cancer cell lines with promising results. Its ability to inhibit kinases makes it a potential candidate for further development as an anticancer drug.

Everolimus related compound 3 is a chemical compound that contains xylose, chamomile extract, cellulose, sulfadiazine, and other ingredients. It is commonly used in industrial applications and has various properties and uses. This compound has been found to have interactions with glutamate, basic proteins, tocopherol, biomass, ticagrelor, chemokines, P. aeruginosa, and other substances. It may also contain impurities such as growth factors and fatty acids. Its specific applications and benefits will depend on the intended use in different industries.

Valdecoxib dimer is a drug product that has been custom synthesized to meet the customer's requirements. It is an analytical standard and is available in high purity. Valdecoxib dimer has been shown to be metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Valdecoxib dimer also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture. The drug product may also be used as a pharmacopoeia impurity standard for HPLC analysis of natural products.

2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid is a synthetic compound that is being researched as a potential drug product. It is an impurity standard for HPLC and has been used in the past to develop drugs. The chemical structure of this compound closely resembles that of the natural metabolite 4,5-dimethoxybenzoic acid, which is found in plants such as thyme. 2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid has shown to inhibit human cytochrome P450 enzymes, which may lead to serious side effects when taken orally.

Polyethylene glycol monoisotridecyl ether (PEG-DTAE) is a polymer that can be used as an antimicrobial agent. It is active against Gram-positive bacteria but not against Gram-negative bacteria. PEG-DTAE has anti-angiogenic effects, which may be due to its ability to inhibit the growth of new blood vessels and thereby prevent the spread of infection. In vitro assays have shown that PEG-DTAE can induce cell lysis and hemolysis in test samples. PEG-DTAE has been shown to have hemolytic activity in vivo in rats, with histology sections showing inflammation and necrosis in the spleen and liver. This polymer also causes symptoms such as fever, chills, rigors, and hypotension in patients with chronic renal failure who are undergoing dialysis.