APIs pour la recherche et les impuretés
Les principes actifs pharmaceutiques (API) sont les substances présentes dans les médicaments qui sont responsables de leurs effets thérapeutiques. Dans cette section, vous trouverez une grande variété d'API destinés à un usage de recherche. Ces composés sont essentiels pour le développement, les tests et la validation de nouvelles formulations pharmaceutiques. Chez CymitQuimica, nous proposons des API de haute qualité pour soutenir la recherche dans la découverte et le développement de médicaments.
Sous-catégories appartenant à la catégorie "APIs pour la recherche et les impuretés"
- Acides Aminés et Dérivés(12.317 produits)
- Anthraquinones et Dérivés(402 produits)
- Dérivés du Benzimidazole et de l’Imidazole(10.383 produits)
- Dérivés des Benzodiazépines(324 produits)
- Glucides et Glycoconjugués(5.045 produits)
- Esters et Dérivés(42.241 produits)
- Acides Gras et Dérivés Lipidiques(32.368 produits)
- Flavonoïdes et Polyphénols(17.070 produits)
- Radicaux Libres et Agents Oxydants/Réducteurs(210 produits)
- Cétones et Dérivés(2.394 produits)
- Antibiotiques Naturels et Semi-Synthétiques(6.310 produits)
- Nitriles et Dérivés Cyano(3.068 produits)
- Nitrosamines et Dérivés(55 produits)
- Nucléosides et Nucléotides(3.427 produits)
- Phosphates et Phosphonates Organiques(1.193 produits)
- Sulfonates et Sulfates Organiques(10.416 produits)
- Composés Organométalliques(4.417 produits)
- Autres(6.266 produits)
- Peptides et Protéines(3.130 produits)
- Polymères et Dérivés(99 produits)
- Dérivés des Purines et Pyrimidines(8.893 produits)
- Dérivés de Quinazoline et de Quinoléine(65.624 produits)
- Quinones et Dérivés(24.336 produits)
- Sels et Dérivés d’API(81.450 produits)
- Stéroïdes et Dérivés(4.911 produits)
- Sulfamides et Dérivés(2.556 produits)
- Terpénoïdes et Dérivés(3.830 produits)
- Thiazolidinediones et Thiopyranes(2.752 produits)
- Composés β-Adrénergiques(227 produits)
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58824 produits trouvés pour "APIs pour la recherche et les impuretés"
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(S)-Rexamino
CAS :Produit contrôlé(S)-Rexamino is an analog of kinases that acts as a potent inhibitor of protein kinase. It has been found to be effective in the treatment of cancer by inducing apoptosis in human cancer cells. (S)-Rexamino also has inhibitory effects on tumor growth and is considered an anticancer agent. This toxin has been shown to be effective against Chinese hamster ovary cells, which are often used in cancer research. Additionally, (S)-Rexamino can be detected in urine samples and may have potential as a diagnostic tool for certain types of cancers. With its potent inhibitory effects on kinases, (S)-Rexamino shows great promise as a potential treatment option for various forms of cancer.Formule :C9H10N2ODegré de pureté :Min. 95%Masse moléculaire :162.19 g/mol25-Hydroxy previtamin D3
CAS :25-Hydroxy previtamin D3 is a metabolite of vitamin D3. It is a natural compound that is synthesized in the skin by exposure to sunlight. 25-Hydroxylase activity converts vitamin D3 to 25-hydroxyvitamin D3, which then undergoes hydroxylation at position 1 by cytochrome P450 enzymes in the liver and kidney. 25-Hydroxy previtamin D3 can be used as an impurity standard for HPLC analysis of vitamin D compounds.Degré de pureté :85%Min3-(Aminomethylene)-6-phenyl-2,5-piperazinedione
CAS :3-(Aminomethylene)-6-phenyl-2,5-piperazinedione is a potent anticancer agent that has shown promising results in inhibiting cancer cell growth. This compound is an analog of etomidate, a drug used for anesthesia induction. It has been found to induce apoptosis in human tumor cells and inhibit the activity of kinases, which are enzymes involved in cancer progression. The compound has also been detected in human urine, indicating its potential for use as a biomarker for cancer diagnosis and treatment monitoring. Additionally, 3-(Aminomethylene)-6-phenyl-2,5-piperazinedione has shown inhibitory effects on elastase activity, which may contribute to its potential as a therapeutic agent against cancer.
Formule :C11H11N3O2Degré de pureté :Min. 95%Masse moléculaire :217.22 g/molRacecadotril Impurity G
CAS :Racecadotril Impurity G is an analytical impurity found in the drug Racecadotril. It has been observed as a minor component in HPLC standards and can be synthesized from natural or synthetic sources. Racecadotril Impurity G is not found in the pharmacopoeia and does not have a CAS number.Formule :C19H21NO3SDegré de pureté :Min. 95%Masse moléculaire :343.44 g/mol5-[4’-Carboxy-(1,1’-biphenyl)-2-yl]-2-triphenylmethyltetrazole
CAS :5-[4’-Carboxy-(1,1’-biphenyl)-2-yl]-2-triphenylmethyltetrazole is a versatile compound with various applications. It has been found to exhibit steroid-like properties and interacts with dopamine receptors. Additionally, it has shown antiviral activity against certain viruses such as tenofovir and blonanserin.
Formule :C33H24N4O2Degré de pureté :Min. 95%Masse moléculaire :508.6 g/molAG-024322
CAS :AG-024322 is an analog of a Chinese medicinal herb that has been found to have potent anticancer properties. It works by inhibiting cyclin-dependent kinases, which are enzymes that regulate the cell cycle and play a crucial role in cancer cell growth. AG-024322 has been shown to induce apoptosis, or programmed cell death, in cancer cells. This inhibitor of protein kinase has also demonstrated efficacy against various types of tumors in human studies. AG-024322 is one of several promising inhibitors of this class currently being developed as potential cancer treatments.Formule :C23H20F2N6Degré de pureté :Min. 95%Masse moléculaire :418.4 g/molN1-Losartanyl-losartan
CAS :N1-Losartanyl-losartan is a new nonpolar, innovative pharmaceutical agent that fulfills the needs of pharmacological research. It has been shown to be pharmacologically active in vivo and in vitro. N1-Losartanyl-losartan has been shown to be genotoxic impurities, nitrosamines, and other impurities. N1-Losartanyl-losartan is an analytical method for the determination of valsartan and its metabolites. The analytical method uses supercritical fluid chromatography with mass spectroscopy detection (SFC/MSD).Formule :C44H44Cl2N12ODegré de pureté :95%NmrMasse moléculaire :827.81 g/molN-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 2-ethylbutyl ester
CAS :Remdesivir impurityFormule :C21H27N2O7PDegré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :450.42 g/mol[[5-[[(2-Aminoethyl)thio]methyl]furan-2-yl]methyl]dimethylamine, hemifumarate
CAS :Ai Product Descriptions 50 CreativeFormule :C10H18N2OS·2C4H4O4Degré de pureté :Min. 95%Masse moléculaire :446.47 g/molBenz[A]anthracene-7-acetic acid methyl ester
CAS :Please enquire for more information about Benz[A]anthracene-7-acetic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C21H16O2Degré de pureté :Min. 95%Masse moléculaire :300.3 g/molRedaporfin
CAS :Redaporfin is an analog of the protein kinase inhibitor quetiapine, which has shown potential as an anticancer agent. It works by inhibiting kinases that are involved in cancer cell growth and proliferation. Redaporfin has been shown to induce apoptosis in human tumor cells, making it a promising candidate for cancer treatment. This drug has also been found to be effective against Chinese hamster ovary cells when tested in urine samples. Additionally, Redaporfin has been found to have inhibitory effects on other proteins, making it a versatile tool for researchers studying protein interactions and signaling pathways.Formule :C48H38F8N8O8S4Degré de pureté :Min. 95%Masse moléculaire :1,135.1 g/mol1,4-Di-2-furoylpiperazine
CAS :1,4-Di-2-furoylpiperazine is a synthetic compound that has been shown to have anti-inflammatory and analgesic properties. It was originally developed as a pharmaceutical drug candidate for the treatment of arthritis and other inflammatory disorders. 1,4-Di-2-furoylpiperazine is an impurity in the synthesis of the drug product diclofenac. The compound is also found as a metabolite in humans after oral administration of diclofenac. 1,4-Di-2-furoylpiperazine binds to protein and inhibits protein synthesis by preventing amino acid incorporation into proteins. It also has nicotinic effects on acetylcholine binding sites and can be used as an analytical standard for HPLC analysis of drugs containing this molecule.Formule :C14H14N2O4Degré de pureté :Min. 95%Masse moléculaire :274.27 g/molErythromycin EP impurity L
CAS :Erythromycin EP impurity L is a metabolite of erythromycin that is found in the urine of patients taking erythromycin. It is a white to light yellow crystalline powder. Erythromycin EP impurity L has been used as an analytical standard for HPLC and GC-MS, and as a pharmacopoeia reference material. Erythromycin EP impurity L is also known to have anti-inflammatory properties.Degré de pureté :Min. 95%ITE analog
CAS :ITE analog is an anticancer agent that works by inhibiting the activity of certain kinases in cancer cells. This inhibitor has been shown to induce apoptosis and inhibit tumor growth in both human and Chinese hamster ovary cell lines. ITE analog is a protein toxin that can be found in urine, but the synthetic analog is more potent and selective than the natural compound. This analog has been tested against a variety of kinases, including those involved in cancer cell proliferation, and has shown promising results as a potential treatment for cancer. Its unique mechanism of action makes it a valuable addition to the arsenal of anticancer drugs available today.Formule :C15H12N2O2SDegré de pureté :Min. 95%Masse moléculaire :284.3 g/molFluorometholone delta 9,11
CAS :Produit contrôléFluorometholone delta 9,11 is a drug product that is used as an analytical reference standard for the quantitative determination of impurities in drugs. It is a natural metabolite and impurity in synthetic drugs such as fluoroquinolones and corticosteroids. Fluorometholone delta 9,11 has been shown to be a substrate for CYP3A4 and P-glycoprotein. This drug has also been shown to have anti-inflammatory effects and may decrease the risk of infection by suppressing neutrophil function.Formule :C22H28O3Degré de pureté :Min. 95%Masse moléculaire :340.46 g/molMilrinone impurity 7
CAS :Milrinone impurity 7 is a synthetic impurity of Milrinone. It is a white, crystalline solid that is soluble in water and methanol. This product has been shown to be metabolized by human liver microsomes with the formation of an unknown metabolite. Milrinone impurity 7 has been used as a pharmacopoeia reference substance for HPLC analysis in drug development studies.Formule :C14H13N3ODegré de pureté :Min. 95%Masse moléculaire :239.27 g/molRS 45041-190 hydrochloride
CAS :RS 45041-190 hydrochloride is a selective antagonist of the imidazoline receptor, which is a type of receptor ligand. RS 45041-190 hydrochloride blocks the binding of dopamine to its receptors in the cerebral cortex and blood pressure regulation. This drug also blocks adrenoceptors and 5-hydroxytryptamine (5-HT) receptors. RS 45041-190 hydrochloride is an equated drug that has been shown to be effective for inflammatory pain caused by nerve injury. It has not been proven to be effective for other types of pain.
Formule :C11H13Cl2N3Degré de pureté :Min. 95%Masse moléculaire :258.14 g/molPantoprazole N-oxide
CAS :Pantoprazole is a proton pump inhibitor that inhibits the gastric acid secretion by blocking the hydrogen/potassium ATPase enzyme in the stomach. Pantoprazole N-oxide, a prodrug of pantoprazole, is converted to pantoprazole after administration and has been shown to be more stable than pantoprazole. It has been shown to have tissue-specific effects, with high concentrations found in gastrointestinal tissues such as the abomasum, ileum, and colon. Pantoprazole N-oxide is also found in plasma samples at low levels. This drug may be useful for ulceration because it prevents heartburn caused by excess stomach acid.Formule :C16H15F2N3O5SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :399.37 g/mol(E)-4-(2,6-Dimethoxystyryl)-3-methoxyphenol-d6
CAS :Please enquire for more information about (E)-4-(2,6-Dimethoxystyryl)-3-methoxyphenol-d6 including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C17H18O4Degré de pureté :Min. 95%Masse moléculaire :286.32 g/molMacrophin
CAS :Macrophin is a promising drug candidate for cancer treatment that has shown potent antiproliferative activity against various cancer cell lines, including human lung and ovarian cancer cells. It works by inhibiting the production of proteins vital for cell division, thereby preventing cancer cells from multiplying. Macrophin's molecular mechanisms have been extensively studied, and it has been found to induce apoptosis in cancer cells. In addition to its anti-cancer properties, Macrophin also exhibits antifungal activity and can be used as a potential treatment for fungal infections. This drug is produced in high yield, making it an attractive option for drug development. Its inhibitory activity against cancer cells makes it a valuable tool in the fight against cancer.Formule :C17H20O8Degré de pureté :Min. 95%Masse moléculaire :352.3 g/molCalcipotriol EP Impurity I
Calcipotriol EP Impurity I is a metabolite of calcipotriol which acts as a natural, synthetic and analytical standard for the compound. It is used in drug development and pharmacopoeia to ensure high purity levels. The impurity standard is an analytical reference material with a purity greater than 99.5% and contains no more than 10% of any other impurity.Formule :C27H40O3Degré de pureté :Min. 95%Masse moléculaire :412.6 g/molClarithromycin impurity O
CAS :Clarithromycin impurity O is a crystalline form of clarithromycin that is obtained by the sulfation of the free base. It is prepared by adding an acid binding agent to the free base and then dissolving it in water. The sulfate salt of clarithromycin impurity O can be purified by recrystallization. Clarithromycin impurity O has been used as a raw material for clarithromycin, which is a β-lactam antibiotic with activity against Gram-positive bacteria and some Gram-negative bacteria. Clarithromycin impurity O is also used in other pharmaceuticals such as anti-inflammatory drugs and antibiotics. The preparation process starts with the methylation reaction of potassium hydroxide, followed by hydrolysis to produce methyl sulfate and dimethyl sulfate. The methylated product is purified through distillation, vacuum drying, or crystallization, yielding a pure form of methylated product that can be further processed into otherFormule :C39H72N2O13Degré de pureté :Min. 95%Masse moléculaire :776.99 g/mol(+)-Geosmin
CAS :(+)-Geosmin is a protein that has shown promising medicinal properties as an inhibitor of tumor growth and apoptosis inducer in human Chinese hamster ovary cells. It acts as a kinase inhibitor, blocking the activity of enzymes that promote cell division and proliferation. Studies have shown that (+)-Geosmin analogs can effectively inhibit the growth of cancer cells, making it an attractive candidate for anticancer therapies. Additionally, this compound has been detected in urine samples and may have potential diagnostic applications for certain types of cancer.Formule :C12H22ODegré de pureté :Min. 95%Masse moléculaire :182.3 g/molClindamycin phosphate EP impurity G
Clindamycin phosphate EP impurity G is a metabolite of clindamycin that can be found in the urine of patients taking clindamycin. It is a white to off-white crystalline solid with a melting point of about 205°C. Clindamycin phosphate EP impurity G has been used as an analytical reference standard for clindamycin, and it is also used as a synthetic intermediate in the drug development process. The CAS number for this compound is 719-72-4.
Formule :C18H33N2O8PSDegré de pureté :Min. 95%Masse moléculaire :468.5 g/mol(3α)-Allopregnanolone sulfate
CAS :(3α)-Allopregnanolone sulfate is a medicinal compound with potential anticancer properties. It is an analog of the natural hormone allopregnanolone and has been shown to inhibit kinases involved in cancer cell proliferation and survival. This compound induces apoptosis, or programmed cell death, in cancer cells by targeting proteins that regulate cell growth and division. (3α)-Allopregnanolone sulfate has been studied as a potential inhibitor of tumor growth in human cancer cells and has shown promising results. It can be detected in urine samples and has also been used in Chinese traditional medicine for its medicinal properties.
Formule :C21H34O5SDegré de pureté :Min. 95%Masse moléculaire :398.6 g/mol6-Chloro-2-(chloromethyl)-4-phenyl-quinazoline
CAS :6-Chloro-2-(chloromethyl)-4-phenyl-quinazoline is a phenyl ring with an oxide group at the 6 position and a chlorodiazepoxide group at the 2 position. It is used in dermatitis, as it inhibits the release of histamines. This drug has been shown to have sensitized reactions in guinea pigs, and dimers are formed when it reacts with skin tissue. 6-Chloro-2-(chloromethyl)-4-phenyl-quinazoline can form dihedral or centrosymmetric quinazolines by reacting with hydrazine and benzodiazepine. The formation of these compounds is dependent on the presence of hydrazines and benzodiazepines, which may be found in certain household products such as detergents or cosmetics. This compound also forms supramolecular assemblies that stack on top of one another like a deck of cards, which may be due toFormule :C15H10Cl2N2ODegré de pureté :Min. 95%Masse moléculaire :305.2 g/molNaringenin 4'-o-β-D-glucuronide sodium
CAS :Naringenin 4'-o-β-D-glucuronide sodium salt is an analog of naringenin, a flavonoid found in Chinese herbs and citrus fruits. It has been shown to possess potent anticancer activity by inhibiting cyclin-dependent kinases (CDKs) and inducing apoptosis in cancer cells. Naringenin 4'-o-β-D-glucuronide sodium salt acts as a protein kinase inhibitor that disrupts the signaling pathways involved in tumor growth and metastasis. This compound has been found to be effective against various types of cancer, including breast, lung, prostate, and colon cancer. It is excreted in human urine and can be used as a biomarker for evaluating the efficacy of cancer treatment. Overall, this sodium salt has great potential as an inhibitor of tumor cell proliferation and may be a promising therapeutic agent for cancer treatment.
Formule :C21H20O11•NaxDegré de pureté :Min. 95%Masse moléculaire :448.4 g/mol4-[(2,3,4-Trimethoxyphenyl)methyl]-1-piperazinecarboxylic acid ethyl ester
CAS :4-[(2,3,4-Trimethoxyphenyl)methyl]-1-piperazinecarboxylic acid ethyl ester is an impurity standard for HPLC. It is a white or off-white solid that is soluble in organic solvents. The compound has been shown to be a metabolite of the drug product, and can also be found as an impurity in the API. 4-[(2,3,4-Trimethoxyphenyl)methyl]-1-piperazinecarboxylic acid ethyl ester can be synthesized from 2,3,4-trimethoxybenzoic acid and 1-(2-chloroethyl)piperazine.Formule :C17H26N2O5Degré de pureté :Min. 95%Masse moléculaire :338.4 g/molNps alx 4a dihydrochloride
CAS :NPS-ALX-4A is a drug, which has been shown to have cognition-enhancing effects in mice. It is a 5-HT6 receptor antagonist and can be used as an animal model for human cognitive disorders. NPS-ALX-4A was administered orally to control mice and the animals were tested for learning and memory. The study showed that NPS-ALX-4A improved spatial memory in the mouse model. This drug has not been tested on humans, but it has shown cognitive benefits in the mouse model with no significant side effects.Formule :C25H27Cl2N3O2SDegré de pureté :Min. 95%Masse moléculaire :504.5 g/molThymol sulfate potassium
CAS :Thymol sulfate potassium salt is a drug product that has been used in the clinical setting for over 40 years. It is an analytical standard, and an impurity in various drugs. It is also a natural compound found in many plants (e.g., thyme) and foods (e.g., oregano). Thymol sulfate potassium salt is synthesized from thymol by sulfation with potassium hydroxide and sulfuric acid. The drug development process includes researching and developing new drugs, as well as testing them to ensure they are safe and effective.Formule :C10H14O4S•KDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :269.38 g/molN4-(5-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine
CAS :N4-(5-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine is a synthetic compound that is used as an impurity standard in the synthesis of a number of drugs. It is also used for research and development purposes. N4-(5-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine can be used as an analytical reference material for high performance liquid chromatography (HPLC) methods. This compound was synthesized from 5-(chloromethyl)quinoline and diethylamine.Formule :C18H26ClN3Degré de pureté :Min. 95%Masse moléculaire :319.9 g/mol7-Hydroxy chlorpromazine hydrochloride
CAS :Chlorpromazine is a cholinergic drug that is used to treat psychiatric patients. It has been shown to be effective in the treatment of schizophrenia and other psychotic disorders. Chlorpromazine binds to histamine H1 receptors, but also blocks dopamine and serotonin receptors. This drug has a long half-life in plasma (14.4 hours) and tissues, which may be due to its metabolites. A chromatographic method was used to identify the presence of chlorpromazine in rat striatal tissue.Formule :C17H20Cl2N2OSDegré de pureté :Min. 95%Masse moléculaire :371.32 g/molMethapyrilene fumarate
CAS :Methapyrilene fumarate is a synthetic maleate salt of methapyrilene. This drug is used in the treatment of high blood pressure. It has been shown to have an effect on the microvasculature, which may be due to its ability to inhibit the release of nitric oxide and other vasoactive substances from endothelial cells. Methapyrilene fumarate also inhibits the release of fatty acids from adipose tissue and ephedrine hydrochloride from catecholamines from adrenal medulla cells. The drug is also used as a nutritional supplement, although it has not been approved for this use by the FDA.Formule :C40H50N6O12S2Degré de pureté :Min. 95%Masse moléculaire :871 g/mol(10E,12E)-10,12-Hexadecadienol
CAS :(10E,12E)-10,12-Hexadecadienol is an analog of a Chinese herbal compound that has been shown to have anticancer properties. It acts as an inhibitor of kinases, which are enzymes involved in cell signaling pathways that regulate cell growth and division. This compound has been found to induce apoptosis, or programmed cell death, in cancer cells. (10E,12E)-10,12-Hexadecadienol has also been shown to inhibit the growth of tumors in human studies. Additionally, this compound has been identified in urine samples from individuals taking the diabetes medication vildagliptin, suggesting its potential use as a biomarker for drug efficacy. Overall, (10E,12E)-10,12-Hexadecadienol shows promising potential as a natural anticancer agent with multiple therapeutic applications.Formule :C16H30ODegré de pureté :Min. 95%Masse moléculaire :238.41 g/molDorzolamide impurity C hydrochloride
Impurity C is a by-product of dorzolamide hydrochloride. It is used as an analytical reference material, in drug development and as an impurity standard for HPLC. It is also used to generate a pharmacopoeia monograph. The CAS number for Impurity C is 70585-27-5.Degré de pureté :Min. 95%Fijimycin B
CAS :Fijimycin B is a medicinal compound that acts as an inhibitor of kinases, which are proteins that play a crucial role in cancer cell growth and proliferation. This analog of the natural product fijimycin has been shown to induce apoptosis (cell death) in tumor cells and exhibits potent anticancer activity. Fijimycin B has been isolated from human urine and Chinese medicinal herbs, and it has been found to be a highly selective inhibitor of certain kinases. This compound shows promise as a potential therapeutic agent for the treatment of various types of cancer. Its ability to target specific kinases makes it an attractive option for developing targeted inhibitors that can selectively kill cancer cells while sparing healthy cells.Formule :C42H66N8O11Degré de pureté :Min. 95%Masse moléculaire :859 g/molCefpodoxime proxetil impurity E
CAS :Cefpodoxime proxetil impurity E is an active compound that belongs to the group of mixtures. It has been shown to have a film-forming property and it may contain sugar.
Formule :C22H27N5O10S2Degré de pureté :Min. 95%Masse moléculaire :585.61 g/molCaptopril-cysteine disulfide
CAS :Captopril-cysteine disulfide is an inhibitor that has been shown to induce apoptosis in cancer cells. It is a potent anticancer agent and has been found in human urine. This compound is an analog of capsaicin, which is known for its anticancer properties. Captopril-cysteine disulfide inhibits the activity of protein kinases, which are enzymes involved in cell growth and division. It has been shown to be effective against a variety of cancer types, including those of the lung, breast, and prostate. In Chinese hamster ovary cells, this compound inhibited the growth of tumor cells by up to 50%. Captopril-cysteine disulfide may have potential as a therapeutic agent for cancer treatment.Formule :C12H20N2O5S2Degré de pureté :Min. 95%Masse moléculaire :336.4 g/mol(2S,2R,Cis)-saxagliptin
CAS :(2S,2R,Cis)-saxagliptin is a drug product that has been developed for the treatment of type II diabetes. It is an orally active DPP-4 inhibitor that inhibits the degradation of GLP-1 and GIP and lowers blood glucose levels in patients with type II diabetes mellitus. It binds to the serine/threonine protein phosphatase catalytic site of DPP-4. (2S,2R,Cis)-saxagliptin can be used as a standard for HPLC analysis and as a research and development compound in the study of its metabolism. This drug product is not on the World Health Organization's list of essential medicines. (2S,2R,Cis)-saxagliptin is also not on the United States Pharmacopeia’s list of approved drugs.Formule :C18H25N3O2Degré de pureté :Min. 95%Masse moléculaire :315.40 g/mol2-(((4-Methyl-7-oxyooctyl)oxy)carbonyl)cyclohexanecarboxylic acid
CAS :2-(((4-Methyl-7-oxyooctyl)oxy)carbonyl)cyclohexanecarboxylic acid (2MEOCA) is a metabolite of progesterone which has been detected in human urine. 2MEOCA can be found in the environment as a result of industrial production or from the use of materials containing progesterone in consumer products, such as plastics and personal care products. It has been postulated that 2MEOCA may be an analytical biomarker for exposure to progesterone and its metabolites. 2MEOCA is stable in urine samples stored at room temperature for at least 24 hours and can be measured by a high performance liquid chromatography - mass spectrometry (HPLC-MS/MS) method. The median concentration of 2MEOCA was found to be 0.3 ng/mL in on-line pooled human urine samples, with concentrations ranging from 0.1 ng/mLFormule :C17H28O5Degré de pureté :Min. 95%Masse moléculaire :312.4 g/mol[4-(4-Amino-6-hydroxy-7-methoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)-methanone
CAS :4-(4-Amino-6-hydroxy-7-methoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)-methanone (CAS No. 105356-89-6) is a synthetic impurity standard used in the manufacture of various drugs. Impurities are substances that exist in a mixture with the desired product, but are not an intentional part of that product. Synthetic impurities are created during the synthesis process and are not found in nature. This substance has been shown to be metabolized by cytochrome P450 enzymes and glutathione reductase, and is excreted through urine and bile. It also binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.Formule :C18H23N5O4Degré de pureté :Min. 95%Masse moléculaire :373.41 g/mol25-Hydroxy vitamin d3 3-sulfate sodium salt
CAS :25-Hydroxy vitamin D3 3-sulfate sodium salt is a unique compound that exhibits various characteristics and functions. It is derived from dimethyl fumarate, tenofovir, dopamine, and other substances. This compound acts as a steroid and plays a crucial role in maintaining the body's overall health.Formule :C27H44O5SDegré de pureté :Min. 95%Masse moléculaire :480.7 g/molSb 205607 dihydrobromide
CAS :Sb 205607 dihydrobromide is a chemotherapeutic agent that has been shown to inhibit the growth of cancer cells in vitro. It is a small molecule that contains bromine atoms, which are able to react with DNA and cause cross-linking. Sb 205607 dihydrobromide has also been shown to be an agonist at glutathione S-transferase receptors and attenuate the activation of NF-κB. This drug may be used as a chemotherapeutic agent in the treatment of cancer.Formule :C23H26Br2N2ODegré de pureté :Min. 95%Masse moléculaire :506.3 g/mol4-(4-Chlorophenyl)-4-hydroxypiperidine
CAS :4-(4-Chlorophenyl)-4-hydroxypiperidine is a chemical compound that has been shown to inhibit the human liver enzyme, cytochrome P450. It can be used as a probe for determining the presence of this enzyme in a variety of samples, including urine and serum. 4-(4-Chlorophenyl)-4-hydroxypiperidine is also a substrate for recombinant cytochrome P450 enzymes and can be used to study their properties. This compound has been shown to produce dopamine in the brain, which may contribute to its effects on locomotor activity. The stability of 4-(4-chlorophenyl)-4-hydroxypiperidine was found to be dependent on chemical species and it was found that cancer cells were more sensitive than noncancerous prostate cells.Formule :C11H14ClNODegré de pureté :Min. 95%Masse moléculaire :211.69 g/molN’-(4-Aminophenyl)-N,N-dimethylacetamidine
CAS :N’-(4-Aminophenyl)-N,N-dimethylacetamidine (ADAA) is a cholinergic anthelmintic drug that is effective against endoparasites. It has been shown to be effective against caenorhabditis, resistant mutants and acetylcholine receptor. ADAA is administered to animals and humans orally or intravenously. The pharmacokinetics of ADAA have been studied in rats, mice, pigs and humans. ADAA has a long half-life in rats and mice but not in humans.Formule :C10H15N3Degré de pureté :Min. 95%Masse moléculaire :177.25 g/molPregabalin impurity PD 0312236 and Pregabalin impurity PD 0312237 (mixture of tautomeric isomers)
CAS :Lactose conjugate degradation product of pregabalinFormule :C20H35NO11Degré de pureté :Min. 95%Masse moléculaire :465.49 g/molCefazolin EP Impurity G
CAS :Cefazolin EP Impurity G is a synthetic, impure drug product of cefazolin. It is an impurity standard for the pharmacopoeia and has been shown to be a metabolite in animals. The purity of this compound is unknown. Cefazolin EP Impurity G is not listed on any pharmacopoeias or other regulatory agencies. CAS No.: 1172998-53-6Formule :C11H10N6O4SDegré de pureté :Min. 95%Masse moléculaire :322.3 g/mol(aR)-a-Methyl-N-[3-[4-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine
CAS :(aR)-a-Methyl-N-[3-[4-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine is a synthetic drug product that is used in research and development. It has been shown to have an analytical purity of 99.8%.
Formule :C22H22F3NDegré de pureté :Min. 95%Masse moléculaire :357.41 g/molMe 1207E
CAS :Me 1207E is a potent protein kinase inhibitor that has shown promising results in the treatment of various types of cancer. This analog of a Chinese medicinal compound has been found to induce apoptosis and inhibit cell replication in human cancer cells. Me 1207E has also been shown to be effective as an anticancer agent in animal models, with significant tumor growth inhibition observed in mice. This inhibitor can be detected in urine after administration, making it a convenient option for monitoring therapeutic levels. With its potent activity against cancer cells and promising preclinical data, Me 1207E represents a promising avenue for the development of novel cancer therapies.Formule :C25H28N6O7S3Degré de pureté :Min. 95%Masse moléculaire :620.7 g/mol3-Descyano febuxostat ethyl ester
CAS :3-Descyano febuxostat ethyl ester is a synthetic, natural, and API impurity. 3-Descyano febuxostat ethyl ester is used as an analytical standard in drug development. It is also used as a custom synthesis, impurity standard and analytical reference material.
Formule :C17H21NO3SDegré de pureté :Min. 95%Masse moléculaire :319.40 g/mol
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