APIs pour la recherche et les impuretés

Hydrochlorothiazide is a sulfonamide that inhibits the activity of the enzyme, angiotensin-converting enzyme (ACE), which is responsible for converting angiotensin I to the potent vasoconstrictor, angiotensin II. It also has antihypertensive effects by blocking the production of aldosterone, which causes sodium retention and leads to high blood pressure. It is a byproduct in reactions with substances such as valsartan. Hydrochlorothiazide may react chemically with other medicines such as ampicillin and cefaclor.

Tenofovir disoproxil is the disoproxil fumarate salt of tenofovir. It is a nucleoside reverse transcriptase inhibitor that has been shown to be effective in the treatment of chronic hepatitis B virus (HBV) in combination with emtricitabine and as a single agent in the treatment of HIV-1 infection. Tenofovir disoproxil is available as tablets, capsules, or oral solution. The drug has been shown to cause an increase in serum creatinine levels, which may be due to inhibition of renal tubular secretion of creatinine by tenofovir. This drug should not be used with alafenamide and tenofovir because it can lead to kidney failure and death.

4-(Acetylamino)-3-bromobenzenesulfonyl chloride is a white crystalline powder that is soluble in water, ethanol and chloroform. It has an analytical standard purity of 99% or greater. This compound can be used for research and development purposes as well as for the synthesis of pharmaceuticals. The impurity profile of 4-(acetylamino)-3-bromobenzenesulfonyl chloride includes 3-acetylbenzenesulfonic acid, sodium acetate, ammonium chloride, sodium sulfite, potassium bromide, potassium iodide, potassium carbonate, and potassium citrate.

Please enquire for more information about 2,5-Dioxabicyclo[2.2.1]heptane α-D-galactopyranoside including the price, delivery time and more detailed product information at the technical inquiry form on this page

Bensulide is a potent inhibitor of kinases, which are enzymes that regulate various cellular processes. It has been shown to have anticancer properties by inducing apoptosis in cancer cells. Bensulide is a Chinese medicinal herb that has been used for centuries as a traditional medicine. It is an analog of protein kinase inhibitors and can be used as an inhibitor of tumor growth. Bensulide has also been found in human urine and may have potential as a diagnostic marker for cancer. Its mechanism of action involves the inhibition of protein kinases, which are involved in cell signaling pathways that regulate cell growth and division. Overall, Bensulide shows great promise as an anticancer agent with potent inhibitory effects on cancer cells.

Alpha-[4-(2-dimethylaminoethoxy)phenyl]stilbene (DS) is a synthetic, analytical standard that is used as an impurity in the manufacture of pharmaceutical products. DS is also sold as a reference material for HPLC and GC/MS analysis.

Tri-o-(tert-butyldimethylsilyl) ractopamine is a compound that has been studied for its potential biological effects. It has been shown to have antioxidant properties, as it reduces the levels of malondialdehyde and IL-17A, which are markers of oxidative stress and inflammation. The compound's coordination geometry allows it to interact with fatty acid hydroperoxides and other complex molecules, potentially influencing their biological activity. Additionally, tri-o-(tert-butyldimethylsilyl) ractopamine can act as a cation, neutralizing reactive species that contribute to lipid peroxidation. Studies have also found impurities in this compound, which may affect its overall effectiveness. Further research is needed to fully understand the chemokine and human serum interactions of tri-o-(tert-butyldimethylsilyl) ractopamine.

Please enquire for more information about Deaminoethyl fluvoxamine β-D-glucuronide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 3,5-Diiodo-4-hydroxy-DL-phenyllactic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Trans-trans-4,4'-Iminodimethylenedi(cyclohexanecarboxylic acid) is a hydrophobic particle that is soluble in water. It has an average particle diameter of 20 nm and a viscosity of 10 cps. Trans-trans-4,4'-Iminodimethylenedi(cyclohexanecarboxylic acid) is used in skin care products as a thickener and viscosity enhancer. It provides a silky feel to the skin and improves the skin's elasticity. This product also helps to protect the skin from UV radiation by forming a barrier on the surface of the skin. The natural polymer can be produced from glycerin or amide to produce different properties for different applications. Trans-trans-4,4'-Iminodimethylenedi(cyclohexanecarboxylic acid) is an amphoteric molecule that can react with both acidic

(7Alpha,17Alpha)- 9,17-Dihydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic acid di-gamma-lactone is a synthetic analogue of progesterone. It is used as a drug product for research and development purposes. The product has been shown to be metabolized through the 3beta hydroxysteroid dehydrogenase pathway or the side chain cleavage enzyme pathways. This product has not been evaluated in humans and should not be used for any human applications. (7Alpha,17Alpha)- 9,17-Dihydroxy-3-oxo-pregn-4-ene-7,21 -dicarboxylic acid di gamma lactone is an impurity standard for HPLC analysis of progesterone in urine.

(S)-3-((S)-5-Oxopyrrolidine-2-carbonyl)thiazolidine-4-carboxylic acid is a synthetic compound that is used as an impurity standard for HPLC. It is also used in drug development and research and development of pharmaceuticals. This product was made through custom synthesis and is not natural.

This is a white crystalline compound that has been shown to be effective against glutamic acid-sensitive L-amino acid decarboxylase. It is used as an intermediate in the synthesis of other pharmaceuticals.

N-Ethoxycarbonyl dabigatran ethyl ester is a synthetic compound that is an impurity in the drug product, Dabigatran etexilate (CAS No. 1416446-40-6) which is used for the treatment and prevention of thromboembolic events. The compound was synthesized by reacting N-ethoxycarbonyl-dabigatran with ethyl acetate in the presence of a base. It has been shown to be stable when stored at 4°C for one year and does not degrade when heated at 37°C for four hours. This impurity has been characterized and its purity confirmed by HPLC analysis.

Iothalamic acid-d3 is a drug product that is a natural, synthetic, and API impurity. It is used as an analytical standard in metabolism studies and for the quality control of natural Iothalamic acid-d4. Iothalamic acid-d3 also has pharmacopoeia standards for HPLC and high purity.

Please enquire for more information about o-Methyl malathion α-monoacid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Tetrahydrocurcumin monoglucuronide is an analog of curcumin, a natural compound found in turmeric. It has been shown to have potent anticancer properties by inhibiting kinases involved in cancer cell growth and proliferation. Tetrahydrocurcumin monoglucuronide has also been found to inhibit testosterone production, making it a potential treatment for hormone-dependent cancers such as prostate cancer. This compound induces apoptosis, or programmed cell death, in cancer cells and has been studied extensively for its potential use in Chinese traditional medicine for the treatment of various types of tumors. Tetrahydrocurcumin monoglucuronide is excreted in urine and is a promising candidate for the development of kinase inhibitors for cancer therapy.

1-[2,3-O-Isopropylidene-b-D-ribofuranosyl]-1,2,4-triazole-3-carboxylic acid methyl ester is a synthetic compound that has been shown to inhibit the growth of Mycobacterium tuberculosis in culture. The metabolite is used as an impurity standard for HPLC analysis of this active compound. It has not yet been approved for use as a drug product.