APIs pour la recherche et les impuretés

Applications 2,2'-AZOBIS-(2-METHYLBUTYRONITRILE) (cas# 13472-08-7) is a useful research chemical.
Dangerous Goods Info This compound is forbidden to ship by air under IATA regulations.

Dicyclopropylamine is a molecule that has been clinically developed as a drug. It is an inhibitor of the enzyme tyrosinase, which is involved in the production of melanin, and has been shown to have anti-cancer properties. Dicyclopropylamine hydrochloride has been shown to be effective against aliphatic hydrocarbons such as hexane and cyclohexane, as well as aromatic compounds such as benzene and toluene. This drug can also bind to coordination complexes with high kinetic energy, which may be useful for tumor treatment. Dicyclopropylamine hydrochloride can be used for the clinical treatment of human epidermoid carcinoma.

Naltrexone impurity A is a synthetic, high-purity drug product that is used as an analytical reference standard in the development and manufacture of pharmaceuticals. It is also used as a pharmacopoeia reference standard and to study metabolism. Naltrexone impurity A has been shown to be a major metabolite of naltrexone and can be found in the urine at concentrations of 1-2% following oral administration. This impurity is not active when given orally, but may have activity if injected intravenously or intramuscularly.

Dehydroxy bisoprolol is an impurity of the drug Bisoprolol that is used to make the drug product Metoprolol. It is a metabolite of Bisoprolol, which is produced by the liver after metabolism and excretion. Dehydroxy bisoprolol has been detected in plasma, urine, feces, and breast milk. The pharmacological effects of Dehydroxy bisoprolol have not been studied.

N-Nitroso-N-methyl-4-aminobutyric acid (NMBA) is a solid with a low melting point which has been identified as a potentially carcinogenic component of both tobacco and tobacco smoke. NMBA is also one of a number of nitrosamine impurities which have been found to be present in angiotensin II receptor blocker (ARB) drugs used to treat high blood pressure.

2-[[[(4-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole is a protonated sulfonamide that is used as an analytical method to detect the presence of other drugs in human liver tissue. It has been shown to inhibit the activity of cytochrome P450 3A4 (CYP3A4), one of the enzymes responsible for metabolizing many drugs. Bromoenol lactone and powder diffraction spectrum are two additional analytical methods that can be used to detect 2-[([(4-methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole.

Dapagliflozin Impurity 4 is a research and development impurity standard for the drug Dapagliflozin. Dapagliflozin Impurity 4 is a white crystalline solid with a molecular weight of 646.5 and an empirical formula of C20H22N2O2. It is soluble in water, methanol, ethanol, and acetonitrile. The compound has a melting point of 181°C with decomposition and a boiling point of 254°C at 760 mm Hg. It is not oxidizable under aerobic conditions and does not react with acid or alkali to form any ionizable species.