APIs pour la recherche et les impuretés
Les principes actifs pharmaceutiques (API) sont les substances présentes dans les médicaments qui sont responsables de leurs effets thérapeutiques. Dans cette section, vous trouverez une grande variété d'API destinés à un usage de recherche. Ces composés sont essentiels pour le développement, les tests et la validation de nouvelles formulations pharmaceutiques. Chez CymitQuimica, nous proposons des API de haute qualité pour soutenir la recherche dans la découverte et le développement de médicaments.
Sous-catégories appartenant à la catégorie "APIs pour la recherche et les impuretés"
- Acides Aminés et Dérivés(12.439 produits)
- Anthraquinones et Dérivés(407 produits)
- Dérivés du Benzimidazole et de l’Imidazole(10.464 produits)
- Dérivés des Benzodiazépines(335 produits)
- Glucides et Glycoconjugués(5.389 produits)
- Esters et Dérivés(42.306 produits)
- Acides Gras et Dérivés Lipidiques(32.486 produits)
- Flavonoïdes et Polyphénols(17.100 produits)
- Radicaux Libres et Agents Oxydants/Réducteurs(214 produits)
- Cétones et Dérivés(2.693 produits)
- Antibiotiques Naturels et Semi-Synthétiques(6.406 produits)
- Nitriles et Dérivés Cyano(3.070 produits)
- Nitrosamines et Dérivés(55 produits)
- Nucléosides et Nucléotides(3.491 produits)
- Phosphates et Phosphonates Organiques(1.203 produits)
- Sulfonates et Sulfates Organiques(10.450 produits)
- Composés Organométalliques(4.425 produits)
- Autres(6.338 produits)
- Peptides et Protéines(3.163 produits)
- Polymères et Dérivés(100 produits)
- Dérivés des Purines et Pyrimidines(8.972 produits)
- Dérivés de Quinazoline et de Quinoléine(66.194 produits)
- Quinones et Dérivés(24.378 produits)
- Sels et Dérivés d’API(92.808 produits)
- Stéroïdes et Dérivés(4.986 produits)
- Sulfamides et Dérivés(2.607 produits)
- Terpénoïdes et Dérivés(3.860 produits)
- Thiazolidinediones et Thiopyranes(2.755 produits)
- Composés β-Adrénergiques(231 produits)
Affichez 21 plus de sous-catégories
66898 produits trouvés pour "APIs pour la recherche et les impuretés"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
5-Benzamidolevulinic acid
CAS :5-Benzamidolevulinic acid is an ethylamine derivative that inhibits the enzyme carbonic anhydrase. It is used as a synthetic intermediate in the production of other drugs, such as dopamine and remoxipride. 5-Benzamidolevulinic acid can be found as a metabolite in the urine of humans exposed to this chemical. The major urinary metabolites are 5-benzamidolevulinate, 5-benzamidoethanol, and 2,5-dihydroxybenzoic acid.Formule :C12H13NO4Degré de pureté :Min. 95%Masse moléculaire :235.24 g/molN-Methylnitroacetamide
CAS :N-Methylnitroacetamide is a pyridinium salt used as an additive in pharmaceutical preparations. It is also a drug substance that is used for oral dosage, and has been shown to be active in methylene chloride and organic solvents. This chemical has been found to have a number of impurities, including acidic compounds and organic solvents, which can cause it to degrade over time. The use of this compound requires validation and kinetic studies to ensure it meets the quality standards for its intended use.Formule :C3H6N2O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :118.09 g/molAcetylenedicarboxylic acid methyl ester
CAS :Acetylenedicarboxylic acid methyl ester (ADME) is a potent inhibitor of kinases that play a crucial role in cancer cell growth and apoptosis. It has been shown to exhibit anticancer activity against various tumor cell lines, including Chinese hamster ovary cells and human bladder carcinoma cells. ADME has also been found in urine samples from healthy individuals, indicating its presence in the human body. This compound specifically targets D-xylose kinases, which are overexpressed in certain cancer cells, leading to their growth inhibition and apoptosis induction. As an inhibitor of these kinases, ADME has potential as a therapeutic agent for the treatment of cancer.Formule :C5H4O4Degré de pureté :Min. 95%Masse moléculaire :128.08 g/molN-Methyl-3-(4-naphthol)-3-(2-thienyl) propanamine hydrochloride
CAS :N-Methyl-3-(4-naphthol)-3-(2-thienyl) propanamine hydrochloride is a custom synthesis that has been shown to be a metabolite of naphthalene. It has been used as an impurity standard for N-methyl-3-(4-naphthol)-2-[(5-nitrofuran-2-yl)methyl] propanamine and in metabolism studies.Formule :C18H19NOS•HClDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :333.88 g/mol3-N-didesmethyl-3-N-tosyl azithromycin
3-N-didesmethyl-3-N-tosyl azithromycin is an impurity of azithromycin. It is a white crystalline solid that is soluble in methanol and acetone, but insoluble in water. 3-N-didesmethylazithromycin has been shown to be a metabolite of azithromycin, which can be found as an impurity in the drug product.Formule :C45H79N3O15SDegré de pureté :Min. 95%Masse moléculaire :934.19 g/molMethyl 2-disazobenzoate hydrochloride
CAS :Methyl 2-disazobenzoate hydrochloride is a drug product that is used as an HPLC standard and as a metabolite in the development of drugs. It has been found to be naturally occurring and is a research and development metabolite. Methyl 2-disazobenzoate hydrochloride is also an impurity of API, which can be quantified in analytical studies. It is a synthetic compound with CAS No. 35358-78-2 and it can be used to manufacture high purity pharmaceuticals. Methyl 2-disazobenzoate hydrochloride has been shown to have niche pharmacological effects, such as anti-inflammatory activities.Formule :C8H7N2O2ClDegré de pureté :Min. 95%Masse moléculaire :198.61 g/molAtorvastatin methyl ester
CAS :Atorvastatin methyl ester is a statin drug that inhibits the synthesis of cholesterol and other lipids in the body. It is used to reduce high levels of low-density lipoprotein (LDL) cholesterol, which may lead to heart disease or stroke. Atorvastatin methyl ester has been shown to be effective in reducing the uptake of LDL cholesterol into cells by preventing the formation of LDL particles. This drug also decreases the production of biphosphate-containing phospholipids, which are essential for dendritic cell maturation. The crystalline polymorphs have been characterized by X-ray diffraction and microscopy. Impurities can be detected using ultraviolet spectroscopy, infrared spectroscopy, or nuclear magnetic resonance spectroscopy.
Formule :C34H37FN2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :572.67 g/molN-Despropyl ropinirole hydrochloride
CAS :N-Despropyl ropinirole hydrochloride is a synthetic drug product that is used as a research and development impurity standard. It is also used in the synthesis of other drugs and has been shown to have an analytical purity of 99%. N-Despropyl ropinirole hydrochloride is not active against bacteria, fungi, or viruses.Formule :C13H19ClN2ODegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :254.75 g/molOxytocin
CAS :Natriuretic hormone; induces uterine contraction and lactation
Formule :C43H66N12O12S2Degré de pureté :Min. 98 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :1,007.19 g/mol4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid, ethyl ester 1,1-dioxide
CAS :4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid, ethyl ester 1,1-dioxide (4HMBC) is an organic compound that is used as a precursor in the synthesis of other chemicals. 4HMBC is used to produce xylene, sulfoxide and diethyl ether by reacting with magnesium and ethylene. It is also used in the production of dimethylformamide, a solvent that is useful for the manufacture of many products including pharmaceuticals. 4HMBC reacts with methyl iodide to form 4-(dimethylamino)pyridine which can be used for the synthesis of piroxicam. The chemical has been shown to be effective as an insecticide against ants and cockroaches. It can also be used to synthesize dyes or pigments. The chemical can be obtained by methylating 4HBC with methanol in the presenceFormule :C12H13NO5SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :283.3 g/molDesfluoro atorvastatin
CAS :Desfluoro atorvastatin is a crystalline polymorph of atorvastatin that has been shown to have improved flowrate and dissolution profile compared with the conventional form. Desfluoro atorvastatin is synthesized by adding a fluorine atom to a specific position in the molecule. The synthesis procedure includes chromatographic purification and analysis of impurities, which are then eliminated by diode laser irradiation. Impurities may also be eliminated through hydrogenation or recrystallization.Formule :C33H36N2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :540.65 g/mol1-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethyl-2-(1-piperazinyl)ethoxyethanol
CAS :1-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethyl-2-(1-piperazinyl)ethoxyethanol is a synthetic drug that is used as an analytical reference standard and as an impurity standard for drug development. It is a metabolite of the benzodiazepine diazepam, which has been shown to produce significant changes in the activity of GABA receptors. This product has not been evaluated by the FDA and should be used in laboratory research only.Formule :C29H41N5O3SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :539.73 g/molCalcipotriol EP Impurity H
Calcipotriol EP Impurity H is an impurity found in calcipotriol EP. It is a metabolite of calcipotriol EP, which is the active ingredient in Dovonex. Calcipotriol EP Impurity H can be detected by HPLC with a retention time of 11.5 minutes and its purity can be determined by UV spectroscopy at 254 nm with a purity of >98%. Calcipotriol EP Impurity H can also be synthesized from natural or synthetic sources.Formule :C54H78O5Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :807.19 g/mol4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinecarboxaldehyde
CAS :4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinecarboxaldehyde is a synthetic chemical compound that has not been approved by the FDA. It is a metabolite of the drug product 4-(4-amino-6,7-dimethoxyquinazolin-2yl)-1-piperazinecarboxylic acid hydrochloride. The CAS number for this chemical is 102714-74-9. This product has been synthesized in our laboratory and is available for purchase at Custom Synthesis. This product can be used as an impurity standard for HPLC analysis or as a research and development chemical for drug development and pharmacopoeia purposes.Formule :C15H19N5O3Degré de pureté :Min. 95%Masse moléculaire :317.34 g/mol2-Phenylbutyric acid
CAS :2-Phenylbutyric acid is a product of the oxidation of phenylacetic acid by flavus. 2-Phenylbutyric acid is an inhibitor of contactor reactions that use α1-acid glycoprotein as a chromatographic support. It has been shown to inhibit the reaction mechanism of extractants (e.g., butamirate citrate) with enantiomeric compounds (e.g., creatine). It also inhibits subclinical mastitis in cows and fatty acid synthesis, leading to decreased cholesterol synthesis in humans.
Formule :C10H12O2Degré de pureté :Min. 95%Masse moléculaire :164.2 g/molAmoxicillin impurity 33
CAS :Amoxicillin impurity 33 is a drug product that is used as an analytical standard for impurities in amoxicillin. It is a natural metabolite of amoxicillin, which is obtained from the fermentation of bacteria. This metabolite has been found to be present in human urine and has been detected in commercial preparations of amoxicillin. Amoxicillin impurity 33 is a white powder with a melting point of about 180-185°C.Degré de pureté :Min. 95%(S)-N2-(Methoxymethyl)-N6-proply-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6 diamine)
(S)-N2-(Methoxymethyl)-N6-proply-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6 diamine) is an API impurity. CAS No. for this product is not available. This product is a custom synthesis and can be purchased as a research and development product. It has been shown to inhibit the activity of bacterial DNA gyrase and topoisomerase IV, which maintains the integrity of bacterial DNA. The chemical name for this product is (S)-N2-(Methoxymethyl)-N6-proply-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6 diamine).Formule :C12H23N3OSDegré de pureté :Min. 95%Masse moléculaire :257.4 g/mol2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone
CAS :2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone is a synthetic building block which can undergo reaction with nucleophilic carbon species to afford C-ribosides (via the corresponding hemiacetal). Treatment of 2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone with stronger reducing agents, such as sodium borohydride, affords ring opened products with a stereo-defined poly-oxygenated carbon chain backbone.Formule :C26H26O5Degré de pureté :Min. 98 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :418.48 g/mol5-Methoxy-2-[[(4-Chloro-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-5-methoxy-1H-benzimidazole
CAS :5-Methoxy-2-[(4-chloro-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-5-methoxy-1H benzimidazole is a synthetic drug product. It has been used as a positive control in metabolism studies and as an impurity standard. 5-Methoxy 2-[(4-chloro 3,5 dimethyl 2 pyridinyl)methyl]sulfinyl]-5 methoxy 1H benzimidazole is also a metabolite of the active pharmaceutical ingredient (API) which is used to develop drugs. This chemical is synthesized by custom synthesis and can be obtained at high purity levels. The metabolite of this compound is 5 methoxy 2-[(4 chloro 3,5 dimethyl 2 pyridinyl)methyl]sulfonyl]-5 methoxy 1H benzimidazole.
Formule :C16H16ClN3O2SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :349.84 g/molAcyclovir
CAS :Acyclovir is an antiviral drug that inhibits the replication of herpes viruses by selectively inhibiting viral DNA polymerase. The drug is active against a broad range of herpes viruses, including both types of herpes simplex virus (HSV-1 and HSV-2) and varicella zoster virus. Acyclovir has also been shown to be effective against aciclovir-resistant mutants. This drug can be used as a prophylaxis or in combination with other antiviral agents for the treatment of active infections. Acyclovir can cause headaches, nausea, vomiting, and diarrhea when taken orally. It should not be taken with certain medicines such as aminoglycosides or high doses of aspirin because this may increase the risk for kidney problems.
Formule :C8H11N5O3Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :225.2 g/mol
![1-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethyl-2-(1-piperazinyl)ethoxyethanol](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FID57891.webp&w=3840&q=75)
![5-Methoxy-2-[[(4-Chloro-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-5-methoxy-1H-benzimidazole](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FIM57916.webp&w=3840&q=75)
