APIs pour la recherche et les impuretés
Sous-catégories appartenant à la catégorie "APIs pour la recherche et les impuretés"
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- Composés β-Adrénergiques(231 produits)
57982 produits trouvés pour "APIs pour la recherche et les impuretés"
N-Ethyl fluprostenol carboxamide
CAS :N-Ethyl fluprostenol carboxamide is a synthetic compound with a chemical formula of C17H21NO4. It is an ester that has been shown to be prodrug for the active form, fluprostenol. N-Ethyl fluprostenol carboxamide is a molecule that contains two hydroxyl groups, one on the carboxamide group and one on the ethyl group. The chemical structure also contains a halogen atom and an ester group.
Formule :C25H34F3NO5Degré de pureté :Min. 95%Masse moléculaire :485.5 g/molGlipizide EP Impurity F
CAS :Glipizide EP Impurity F is a synthetic impurity that is used as a research and development impurity standard. It has high purity and is pharmacopoeia grade. Glipizide EP Impurity F is also a metabolite of the drug product Glipizide and has been shown to have analytical applications for pharmacokinetic studies. It can be synthesized from natural materials or can be custom synthesized depending on the needs of the customer.
Formule :C11H16N2O4SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :272.32 g/molBrexpiprazole impurity 10
CAS :Brexpiprazole impurity 10 is a drug product that is used as an analytical reference standard for the quality control of brexpiprazole. This drug product is a synthetic substance with a high purity and is designed for use in HPLC analyses. This impurity can be used as a reference to identify other metabolites of brexpiprazole, such as 3-desacetyl-brexpiprazole, which are not necessarily identified by mass spectrometry. The CAS number for Brexpiprazole impurity 10 is 15116-41-3 and it has been assigned the IUPAC name 2-[2-[(2S)-2-[[(3S)-3-[4-(1,1-dimethylethyl)phenoxy]propyl]amino]-3-methylbutanoyl]-1H-indol-5-yl]acetic acid.
Formule :C16H15NO2Degré de pureté :Min. 95%Masse moléculaire :253.3 g/molrac 5-Keto Fluvastatin
CAS :Rac5-Keto Fluvastatin is a synthetic, natural and custom synthesis drug product. It's CAS number is 1160169-39-0. Rac5-Keto Fluvastatin is a metabolite of fluvastatin. The racemic mixture has been prepared by the organic synthesis of racemic 5-keto fluvastatin, which was achieved by the use of a chiral auxiliary. Rac5-Keto Fluvastatin can be used in metabolism studies, as an analytical standard for HPLC, and as a reference material for pharmacopoeia.
Formule :C24H24FNO4Degré de pureté :Min. 95%Couleur et forme :Yellow PowderMasse moléculaire :409.45 g/molOxybutynin impurity C
CAS :Oxybutynin impurity C is a metabolite of the drug product Oxybutynin (CAS No. 1199574-70-3). It is an analytical standard for HPLC, and a natural impurity in the synthesis of Oxybutynin. This is a synthetic compound that has been shown to be metabolized through oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Oxybutynin impurity C has been used as an analytical reference material for drug development and research and development.
Degré de pureté :Min. 95%6-o-Benzyl-4-dehydroxy-4-dimethylphenylsilyl entecavir
CAS :6-o-Benzyl-4-dehydroxy-4-dimethylphenylsilyl entecavir is a synthetic drug product with an API impurity. It's an analytical standard for the metabolite 6-o-benzylidene-4,6-didehydroentecavir (CAS 649761-24-0), which is a natural metabolite of entecavir. The impurity standard is used in research and development to study the drug product's metabolism and to ensure that it meets pharmacopeia standards.Formule :C27H31N5O2SiDegré de pureté :Min. 95%Masse moléculaire :485.7 g/mol11-[3-(Dimethylamino)propyl]-6,11-dihydrodibenz[b,e]oxepin-11-ol
CAS :Dispersants are substances that are used to break up and disperse particles in a liquid. The dispersant 11-[3-(dimethylamino)propyl]-6,11-dihydrodibenz[b,e]oxepin-11-ol is an active substance that is used in the production of granules, tablets or other solidified forms of medicaments. It is a substance that has a physiologically active effect on humans and animals. This product can be applied as droplets or particles.
Formule :C19H23NO2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :297.39 g/molCPI 0610
CAS :CPI 0610 is a medicinal compound that acts as a potent inhibitor of protein phosphorylation. It has been shown to inhibit the cell cycle and promote apoptosis in Chinese hamster ovary cells. CPI 0610 is an effective inhibitor of kinase activity in cancer cells, leading to decreased tumor growth and increased survival rates. In preclinical studies, CPI 0610 has demonstrated efficacy against a wide range of cancers, including breast, prostate, and lung cancer. This inhibitor has also been shown to be effective in human cancer cell lines, making it a promising candidate for future cancer therapies.
Formule :C20H18ClN3O3Degré de pureté :Min. 95%Masse moléculaire :383.8 g/molDaunorubicinol hydrochloride
CAS :Daunorubicin metabolite
Formule :C27H31NO10•HClDegré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :566 g/mol(Z)-Fluvoxamine - EP
CAS :Produit contrôlé(Z)-Fluvoxamine-EP is a drug product that is used as an analytical standard. It is a synthetic metabolite of fluvoxamine, which is a drug used for the treatment of depression. The synthesis of (Z)-fluvoxamine-EP is based on the asymmetric synthesis of fluvoxamine and the use of chiral chromatography to purify the product. This synthetic process allows for the production of high-purity (Z)-fluvoxamine-EP with a purity greater than 99%.
Formule :C15H21F3N2O2Degré de pureté :Min. 95%Masse moléculaire :318.33 g/mol2-[[4-(2-Pyridylsulfamoyl)phenyl]azo]hydroxybenzene
CAS :2-[[4-(2-Pyridylsulfamoyl)phenyl]azo]hydroxybenzene is an impurity found in sulfasalazine. It is a metabolite that is formed by the P450 system in the liver. The metabolic process of 2-[[4-(2-Pyridylsulfamoyl)phenyl]azo]hydroxybenzene has been studied in detail and has been shown to be a major contributor to the pharmacokinetic profile of sulfasalazine. This substance also exhibits antimicrobial activity and inhibits the growth of bacteria, fungi, and viruses.
Formule :C17H14N4O3SDegré de pureté :Min. 95%Masse moléculaire :354.38 g/mol2-((2-Methyl-1-(propionyloxy)propoxy)(4-phenylbutyl)phosphoryl)acetic acid
CAS :2-((2-Methyl-1-(propionyloxy)propoxy)(4-phenylbutyl)phosphoryl)acetic acid (KZPBA) is a zoonotic antibiotic that has been shown to be active against agalactiae. It is a prodrug, which is metabolized to the active form, KZPBA, in humans and other mammals. The mechanism of action of KZPBA is not yet known; however, it has been hypothesized that its activity may be due to inhibition of DNA gyrase and topoisomerase IV. This drug has also been shown to have an effect on mastitis in dairy cows.Formule :C19H29O6PDegré de pureté :Min. 95%Masse moléculaire :384.4 g/molMinocycline EP Impurity H
CAS :Please enquire for more information about Minocycline EP Impurity H including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C23H25N3O7Degré de pureté :Min. 95%Masse moléculaire :455.47 g/mol(E)-2-Furaldehyde, (2,4-dinitrophenyl)hydrazone
CAS :Please enquire for more information about (E)-2-Furaldehyde, (2,4-dinitrophenyl)hydrazone including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C11H8N4O5Degré de pureté :Min. 95%Masse moléculaire :276.2 g/molLy 2389575 hydrochloride
CAS :Ly 2389575 hydrochloride is a drug product for the treatment of rheumatoid arthritis, psoriatic arthritis, and plaque psoriasis. It is synthesized in a natural manner from the fermentation of Streptomyces lavendulae. The compound has been shown to be metabolized through a number of metabolic transformations including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Ly 2389575 hydrochloride also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.
Formule :C15H16BrCl3N4Degré de pureté :Min. 95%Masse moléculaire :438.6 g/mol6-Acetoxymethyl-4-methoxy-5-methyl-3-pyridylmethanol o-toluate
CAS :6-Acetoxymethyl-4-methoxy-5-methyl-3-pyridylmethanol o-toluate is a synthetic compound that is used as an analytical reference standard for the metabolism studies. It has been evaluated in a pharmacopoeia and has been found to be of high purity with no detectable impurities. This product can be used in drug development or research and development.
Formule :C19H21NO5Degré de pureté :Min. 95%Masse moléculaire :343.40 g/mol4-(4-Aminophenyl)phthalazin-1(2H)-one
CAS :4-(4-Aminophenyl)phthalazin-1(2H)-one is an antibacterial drug that belongs to the class of amide and minimise. It has a constant, synthetic, and chalcone profile. 4-(4-Aminophenyl)phthalazin-1(2H)-one has been shown to have antiplatelet activity in animals. This drug also inhibits the production of proinflammatory cytokines such as IL-6, IL-8, and TNFα by human monocytes. This drug also has antidiabetic properties and a safety profile similar to other nonsteroidal anti-inflammatory drugs.
Formule :C14H11N3ODegré de pureté :Min. 95%Masse moléculaire :237.26 g/molGenistein 4’-β-D-glucuronide
CAS :Genistein 4’-β-D-glucuronide is an isoflavonoid that is a natural product of soy and red clover, with estrogenic properties. It has been shown to have the ability to bind to estrogen receptors and inhibit the growth of breast cancer cells. Genistein 4’-β-D-glucuronide has been shown to inhibit the production of estrone sulfate in human breast cells, which may be due to its ability to act as an estrogen receptor antagonist. The isoflavonoid genistein also binds to and inhibits the activity of DNA topoisomerase II enzymes in human breast cells.
Formule :C21H18O11Degré de pureté :Min. 95%Masse moléculaire :446.4 g/molBinospirone hydrochloride
CAS :Binospirone hydrochloride is a drug product that is used in the treatment of depression. It belongs to the class of antidepressants and has been shown to be effective against major depressive disorder (MDD). Binospirone hydrochloride is metabolized by cytochrome P450 enzymes into two metabolites: 3-hydroxybinospirone and 2,3-dihydroxybinospirone. The natural form of binospirone hydrochloride is synthesized from tyrosine and phenylalanine. It is also found as an impurity in other pharmaceuticals, such as clomipramine, amitriptyline, and fluoxetine. It has been shown that this compound binds to the serotonin transporter (SERT) at high affinity. This binding inhibits the reuptake of serotonin from synapses, leading to increased extracellular concentrations of serotonin.
Formule :C20H27ClN2O4Degré de pureté :Min. 95%Masse moléculaire :394.9 g/molBoc-3-hydroxy-1-adamantyl-glycine
CAS :Boc-3-hydroxy-1-adamantyl-glycine is a catalytic, nucleophilic, chiral amino acid that is used in the synthesis of oximes. Boc-3-hydroxy-1-adamantyl-glycine has been shown to be an effective substitute for hydroxylamine in reductive amination reactions and can be used to synthesize some pharmaceuticals, including saxagliptin. This compound is stable under standard conditions and can be easily synthesized. It is also a powerful nucleophile that reacts with electrophiles such as chloroformates and sulfonyl chlorides.
Formule :C17H27NO5Degré de pureté :Min. 95%Masse moléculaire :325.4 g/molL(+)-2-Amino-5-phosphonovaleric acid
CAS :L-2-Amino-5-phosphonovaleric acid is an inhibitory neurotransmitter that binds to the GABAA receptor. It is used in the treatment of bladder disorders, such as urinary frequency, urgency, and incontinence. L-2-Amino-5-phosphonovaleric acid has been shown to have a depressant effect on the central nervous system and can cause symptoms such as nausea, vomiting, and headache. This drug also has antimicrobial properties due to its ability to inhibit bacterial enzyme activities. L-2-Amino-5-phosphonovaleric acid blocks glutamate receptors in mouse hippocampal cells by binding the alpha1 subunit of the GABAA receptor. This prevents the influx of calcium ions into cells and inhibits phosphorylation of protein kinase C. L(+)-2-Amino-5-phosphonovaleric acid also inhibits pentosan polysulfate sodium,
Formule :C5H12NO5PDegré de pureté :Min. 95%Masse moléculaire :197.13 g/molN-Desbispropyl-N-pentyl-2-methyl ropinirole
CAS :N-Desbispropyl-N-pentyl-2-methyl ropinirole is an analytical reference standard. This product is a high purity, drug development, and API impurity. It is a CAS No. 249622-60-4 and has a niche, drug product, and impurity standard. This item is for Research and Development, High purity, Drug development, API impurity, HPLC standard, CAS No. 249622-60-4, niche, drug product, Impurity standard, Metabolite, pharmacopoeia Custom synthesis of natural or synthetic origin.
Formule :C16H24N2ODegré de pureté :Min. 95%Masse moléculaire :260.37 g/molDuloxetine phenyl carbamate
CAS :Duloxetine is a drug product that belongs to the class of drugs known as selective serotonin and norepinephrine reuptake inhibitors. Duloxetine is a metabolite of duloxetine phenyl carbamate, which is an impurity standard for HPLC analysis. Duloxetine has been shown to inhibit the metabolism of serotonin and norepinephrine in the brain, leading to increased amounts of these neurotransmitters. This medication has been studied in niche populations such as those with depression and diabetic neuropathy. Duloxetine also has high purity standards, meeting the requirements of pharmacopoeia.
Formule :C25H23NO3SDegré de pureté :Min. 95%Masse moléculaire :417.50 g/molHydrocortisone 17-valerate 21-acetate
CAS :Produit contrôléPlease enquire for more information about Hydrocortisone 17-valerate 21-acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C28H40O7Degré de pureté :Min. 95%Masse moléculaire :488.6 g/mol4'-Bromo-2-(diethylamino)-2',6'-acetoxylidide
CAS :Please enquire for more information about 4'-Bromo-2-(diethylamino)-2',6'-acetoxylidide including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C14H21BrN2ODegré de pureté :Min. 95%Masse moléculaire :313.23 g/molN9-Des(4-acetoxy-3-(acetoxymethyl)but-1-yl) N7-[4-acetoxy-3-(acetoxymethyl)but-1-yl] famciclovir
CAS :N9-Des(4-acetoxy-3-(acetoxymethyl)but-1-yl) N7-[4-acetoxy-3-(acetoxymethyl)but-1-yl] famciclovir is an analytical standard that is used for drug development and as an impurity in the production of famciclovir. It has a purity of 99.0% and a melting point of 176°C. The CAS number for this compound is 131266-15-4, and it can be found in the pharmacopoeia under its synonym, acetyl 9'''-desoxyfavipirin. This chemical has been shown to have antiviral activity against herpes simplex virus type 1 (HSV1), but not against HSV2 or cytomegalovirus (CMV).
Formule :C14H19N5O4Degré de pureté :Min. 95%Masse moléculaire :321.33 g/mol1-[2-[2-Hydroxy-3-[[2-hydroxy-3-[2-(3-phenylpropanoyl)phenoxy]propyl]-propylamino]propoxy]phenyl]-3-phenylpropan-1-one
CAS :Arbidol is a drug molecule that interacts with protease enzymes. It has been shown to inhibit human erythrocyte chymotrypsin, trypsin, and elastase. Arbidol is also able to inhibit the growth of bacteria such as Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. The molecular modelling of arbidol suggests that it binds to the active site of the enzyme by blocking hydrophobic pockets on the surface of the enzyme. The conformational change in the protease enzyme activates arbidol's binding site for an extended period of time. This prolonged interaction prevents substrate from binding to the catalytic site of the enzyme and inhibits its activity.
Formule :C39H45NO6Degré de pureté :Min. 95%Masse moléculaire :623.78 g/molZanubrutinib impurity-3
CAS :Please enquire for more information about Zanubrutinib impurity-3 including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C29H33N5O3Degré de pureté :Min. 95%Masse moléculaire :499.6 g/molrac-Norphenylephrine hydrochloride
CAS :Produit contrôléRacemic norphenylephrine hydrochloride is a sympathomimetic amine. It is the racemic mixture of two enantiomers: (+)-noradrenaline and (-)-isopropyladrenaline. Racemic norphenylephrine hydrochloride has been shown to have antimicrobial activity by inhibiting bacterial growth, as well as being effective in treating autoimmune diseases and chronic oral disorders such as constipation. Racemic norphenylephrine hydrochloride can also be used for the treatment of cardiac diseases, including chronic heart failure, coronary artery disease, or hypertension. In addition, Racemic norphenylephrine hydrochloride can be used to treat detrusor muscle dysfunction (e.g., urinary incontinence).
Formule :C8H12ClNO2Degré de pureté :Min. 95%Masse moléculaire :189.64 g/molEthyl 2-methoxy-5-sulfamoylbenzoate
CAS :Ethyl 2-methoxy-5-sulfamoylbenzoate is a research and development impurity standard. It is a white to off-white crystalline solid that is soluble in water. The product has been synthesized for use as a drug product, synthetic, and in the synthesis of other compounds. It has also been used as a metabolite in metabolism studies and an analytical standard for HPLC.
Formule :C10H13NO5SDegré de pureté :Min. 95%Masse moléculaire :259.28 g/molDesmethyl dabrafenib
CAS :Desmethyl dabrafenib is a synthetic drug product that is used in research and development. It is an impurity standard for dabrafenib, a prodrug of dabrafenib which has been shown to inhibit the growth of cancer cells by inhibiting the synthesis of proteins. Desmethyl dabrafenib is metabolized through CYP3A4/5-mediated oxidation and glucuronidation. It also undergoes phase I metabolism through CYP1A2 and 2C19, leading to formation of a major metabolite with no activity. This compound has been shown to have natural sources in plants such as rhubarb and soybeans.
Formule :C22H18F3N5O2S2Degré de pureté :Min. 95%Masse moléculaire :505.50 g/molTenofovir disoproxil
CAS :Tenofovir disoproxil is the disoproxil fumarate salt of tenofovir. It is a nucleoside reverse transcriptase inhibitor that has been shown to be effective in the treatment of chronic hepatitis B virus (HBV) in combination with emtricitabine and as a single agent in the treatment of HIV-1 infection. Tenofovir disoproxil is available as tablets, capsules, or oral solution. The drug has been shown to cause an increase in serum creatinine levels, which may be due to inhibition of renal tubular secretion of creatinine by tenofovir. This drug should not be used with alafenamide and tenofovir because it can lead to kidney failure and death.
Formule :C17H28N5O7P·(C4H4O4)Degré de pureté :Min. 95%Masse moléculaire :445.41 g/molSimvastatin impurity K
Simvastatin impurity K is a research and development substance that is used for the synthesis of drug products. This compound is custom synthesized, and its CAS number is 607-33-0. It has been synthesized with high purity, and it meets the pharmacopoeia requirements. Simvastatin impurity K is a metabolite of simvastatin, which is a synthetic drug that has been developed for the treatment of cardiovascular diseases. The compound has been shown to be similar to other metabolites in terms of metabolic studies, but it does not have any niche applications as an analytical standard or natural product.
Formule :C25H40O5Degré de pureté :Min. 95%Masse moléculaire :420.58 g/molBendamustine isopropyl ester
CAS :Bendamustine isopropyl ester is a synthetic, high purity drug product. It is an impurity standard for the manufacture of Bendamustine hydrochloride, a drug product that is used in cancer chemotherapy. Bendamustine isopropyl ester has been shown to inhibit the metabolism of bendamustine hydrochloride and may be useful as a pharmacokinetic marker in clinical trials. Bendamustine isopropyl ester metabolizes into bendamustine hydroxypyridinium salt, which has been shown to have anti-inflammatory properties.
Formule :C19H27Cl2N3O2Degré de pureté :Min. 95%Masse moléculaire :400.30 g/molN-Desmethyl trimeprazine
CAS :N-Desmethyl trimeprazine is a synthetic compound, which is an impurity of the drug product. It is not active and does not possess any biological activity. It is a metabolite of the parent drug, Trimeprazine. N-Desmethyl trimeprazine has been studied for its pharmacological properties and metabolism in the body, but no conclusive results have been found. The chemical structure and purity of N-Desmethyl trimeprazine are not listed in the USP or BP. This compound can be custom synthesized on request.
Formule :C17H20N2SDegré de pureté :Min. 95%Masse moléculaire :284.40 g/mol4-Methanesulfonyloxybutanol
CAS :4-Methanesulfonyloxybutanol is a chemical substance with the molecular formula CH3SO2CH(CH2OH)CH2OH. It is used as an intermediate in the synthesis of 4-methanesulfonyloxybutanol, which is a potent inhibitor of busulfan-induced leukopenia and myelosuppression. This substance has been shown to be highly effective in preventing busulfan-induced side effects when administered intravenously. 4-Methanesulfonyloxybutanol is chemically synthesized by intramolecular alkylation of butanol, followed by hydrolysis. The reaction product can be detected using an ionization detector in conjunction with gas chromatography. This product is an alkylation agent that reacts with polypropylene to produce polypropylene glycols.
Formule :C5H12O4SDegré de pureté :Min. 95%Couleur et forme :LiquidMasse moléculaire :168.21 g/molAzelastine N-oxide, mixture of diastereomers
CAS :Azelastine N-oxide is a racemic form of azelastine, an antihistamine. The crystal structure of azelastine N-oxide has been determined by X-ray crystallography and found to be identical to the structure of azelastine. Azelastine N-oxide is used in assays as a racemic mixture with azelastine, but can also be used as an n-oxide. Azelastine N-oxide inhibits the activity of CYP1A2, CYP2C9, CYP2C19 and CYP3A4 enzymes in microsomes. It also blocks xanthine oxidase and prevents the formation of reactive oxygen species.Formule :C22H24ClN3O2Degré de pureté :Min. 95%Masse moléculaire :397.9 g/molDehydro nicardipine hydrochloride
CAS :Please enquire for more information about Dehydro nicardipine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C26H28ClN3O6Degré de pureté :Min. 95%Masse moléculaire :514 g/molFR900359
CAS :FR900359 is a drug product that is custom synthesized and characterized. It has a purity of 99% and CAS No. 107530-18-7. This product is used in metabolism studies, natural drug development, pharmacopoeia, and research and development. The impurity standard for this product is HPLC standard.
Formule :C49H75N7O15Degré de pureté :Min. 95%Masse moléculaire :1,002.20 g/mol3-[2-[4-(5-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
CAS :3-[2-[4-(5-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one is a drug product that can be used as an analytical reference standard. It is a synthetic compound that is not found in nature and has CAS number 1199589-74-6. This compound has been synthesized by custom synthesis and it is an impurity standard for HPLC analysis. 3-[2-[4-(5-Fluoro-1,2-benzisoxazol-3 -yl)-1 -piperidinyl]ethyl]-6,7,8,9 -tetrahydro - 2 methyl - 4H - pyrido[1,2 -a]p
Formule :C23H27FN4O2Degré de pureté :Min. 95%Masse moléculaire :410.48 g/mol4-Hydoxymethyl-5-methylimidazol
CAS :4-Hydroxymethyl-5-methylimidazol (HMMI) is a corrosion inhibitor that is used in the production of nanomaterials. It has been shown to be an effective treatment for wastewater containing hydrochloric acid and organic solvents. The reaction between HMMI and the acids in wastewater forms a complex that prevents the corrosion of metal surfaces. HMMI can be synthesized by reacting aesculus with formaldehyde in an organic solvent, such as acetone or chloroform, at room temperature. HMMI has also been shown to have antiviral potency and is used in skin care products, such as lotions and shampoos, due to its ability to penetrate the skin barrier. Magnetic resonance spectroscopy (MRS) was used to study the effect of HMMI on skin cells, while electrochemical methods were used to investigate how it inhibits viral activity.
Formule :C5H8N2ODegré de pureté :Min. 95%Masse moléculaire :112.13 g/molErlotinib-3-vinyl hydrochloride
CAS :Erlotinib-3-vinyl hydrochloride is a drug product that is used in the treatment of cancer, including non-small cell lung cancer. It is an impurity standard for HPLC and analytical testing. Erlotinib-3-vinyl hydrochloride is also used as an API impurity and metabolite in metabolism studies. Erlotinib-3-vinyl hydrochloride can be synthesized from 4-(4'-vinylphenoxy)butanal, which is a natural compound obtained from plants like apple trees. This synthetic process can be done by the reduction of 4-(4'-vinylphenoxy)butanal with sodium borohydride, followed by reaction with vinyl chloride. The compound is also found as a metabolite in humans after oral administration of erlotinib, which has been shown to inhibit protein synthesis and DNA synthesis.
Formule :C22H26ClN3O4Degré de pureté :Min. 95%Masse moléculaire :431.9 g/mol4,6-Dimethoxy-β-methyl-3-phenoxy ambrisentan
CAS :Produit contrôlé4,6-Dimethoxy-β-methyl-3-phenoxy ambrisentan is a synthetic drug with a high purity and pharmacopoeia. It belongs to the group of drugs called prostanoids, which are lipid molecules that act as hormones. 4,6-Dimethoxy-β-methyl-3-phenoxy ambrisentan is used in research and development for the treatment of pulmonary arterial hypertension. It is an impurity standard for HPLC analysis. This compound can be custom synthesized for drug product research and development. Metabolism studies have been conducted on this compound. The metabolites have been identified as 4,6-dimethoxy-(E)-2-[(E)-2-(4'-methylbenzylidene)ethenyl]-3-[(Z)-1-(4'-methylbenzylidene)ethenyl]ambrinol (M1), 4,6-dimethoxy-(E)-Formule :C22H22N2O6Degré de pureté :Min. 95%Masse moléculaire :410.4 g/molN-[[2-[[[4-[[[(Hexyloxy)carbonyl]amino]carbonyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine ethyl ester
CAS :This is an analytical standard for the impurity N-[[2-[[[4-[[(hexyloxy)carbonyl]amino]carbonyl]phenyl]amino]-methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine ethyl ester. It has a purity of >98% by HPLC and is available in quantities of 5g.Formule :C34H40N6O6Degré de pureté :Min. 95%Masse moléculaire :628.7 g/molrac-Pregabalin N-acrylamide
CAS :Pregabalin is an anticonvulsant drug that is used to treat epilepsy, neuropathic pain, and generalized anxiety disorder. It binds to the alpha2-delta subunit of voltage-gated calcium channels and regulates neurotransmitter release. Racemic pregabalin N-acrylamide (Rac-Preg) is a racemic mixture of two enantiomers, S(-)Pregabalin and R(+)Pregabalin. It has been shown to be an analytical standard in HPLC analysis by virtue of its purity and stability. Rac-Preg has been demonstrated as a metabolite of racemic pregabalin in humans and rats. Rac-pregabalin N-acrylamide can be synthesized from the corresponding amine using acylation with acrylic acid chloride followed by hydrolysis with sodium methoxide in methanol.
Formule :C11H19NO3Degré de pureté :Min. 95%Masse moléculaire :213.27 g/molLevofloxacin carboxylic acid
CAS :Levofloxacin is a synthetic molecule with an asymmetric carbon atom in its heterocycle. It is synthesized by reacting chloroform with 2-fluoro-5-nitrobenzaldehyde, which reacts further with sodium hydroxide and hydrochloric acid to form the levofloxacin carboxylic acid. Impurities can be found in the reaction product due to chlorine atoms that are formed during the synthesis. The amount of impurities present in the final product can be determined using a titration method or through HPLC analysis. Levofloxacin has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, although is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex.
Formule :C13H9F2NO4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :281.21 g/molRemdesivir related compound 9
CAS :Remdesivir related compound 9 is a drug product that is an analytical standard. It is a natural API impurity, which has been synthesized for use as an impurity standard. This compound has been custom synthesized to be used as a research and development chemical. CAS No. 1439900-56-7 is the number of this synthetic drug product. It can be used in HPLC standards and it meets pharmacopoeia requirements for purity. The niche market for this compound is high purity analytical standards, including HPLC standards.
Formule :C21H27N2O7PDegré de pureté :Min. 95%Masse moléculaire :450.42 g/molPyrimido[1,2-a]purin-10(1H)-one
CAS :Pyrimido[1,2-a]purin-10(1H)-one is a cytotoxic drug used in the treatment of various cancers. It is an analog of purine nucleoside and has been shown to inhibit mitochondrial functions and nuclear DNA synthesis, as well as to induce malondialdehyde production. Pyrimido[1,2-a]purin-10(1H)-one also inhibits protein synthesis by methyltransferase inhibition. The detection sensitivity of pyrimido[1,2-a]purin-10(1H)-one has been demonstrated using titration calorimetry on sephadex g-100 columns. This compound is not active against E. coli K12 but is active against other bacteria including Staphylococcus aureus isolates that are resistant to methicillin.
Formule :C8H5N5ODegré de pureté :Min. 95%Masse moléculaire :187.16 g/molRef: 3D-DEA40845
Produit arrêtéLinagliptin impurity E
CAS :Produit contrôléLinagliptin impurity E is a metabolite of the drug Linagliptin. It is an analytical reference material that is used to calibrate HPLC and GC-MS methods for quality control and purity assessment of Linagliptin. This impurity standard is also used for metabolism studies.
Formule :C25H28N8O2Degré de pureté :Min. 95%Masse moléculaire :472.54 g/molcis-Tadalafil
CAS :Cis-Tadalafil is a potent inhibitor of phosphodiesterase 5, which is used to treat erectile dysfunction (ED) and primary pulmonary hypertension (PPH). It works by increasing blood flow to the penis, allowing men with ED to achieve and maintain an erection. Cis-Tadalafil is also used to treat symptoms of prostatic hyperplasia (enlarged prostate) in men. This drug has been shown to be effective in treating PPH by reducing pulmonary arterial pressure and improving exercise capacity. Cis-Tadalafil belongs to the carboline class of drugs and is a phosphodiesterase 5 inhibitor that selectively inhibits cGMP-specific phosphodiesterase type 5 (PDE5). This drug has been shown to be highly effective in treating both ED and PPH with minimal side effects.
Formule :C22H19N3O4Degré de pureté :Min. 95%Couleur et forme :White/Off-White SolidMasse moléculaire :389.4 g/molRef: 3D-FT27987
Produit arrêtéTerbinafine dihydrochloride
CAS :Terbinafine is a drug used in the treatment of onychomycosis, tinea versicolor and dandruff. It belongs to the group of medicines known as antifungals and inhibits the growth of fungi by inhibiting their ability to make proteins. Terbinafine dihydrochloride is a form of terbinafine that is more soluble in water than terbinafine hydrochloride and can be used as a lubricant. Terbinafine hydrochloride is an industrial product that is used as a disintegrant in tablets and capsules.
Formule :C36H40N2Degré de pureté :Min. 95%Masse moléculaire :500.7 g/molN-Hydroxymethyl Sumatriptan
CAS :N-Hydroxymethyl Sumatriptan is an analytical standard and a research and development impurity. It is also used as an API impurity in drug product manufacturing. N-Hydroxymethyl Sumatriptan can be synthesized by reacting the parent drug with hydroxyl radicals, which is a process that yields no side products. N-Hydroxymethyl Sumatriptan can be found in the following pharmacopoeia: United States Pharmacopoeia (USP) 11>, European Pharmacopoeia (EP), Japanese Pharmacopoeia (JP)13>, British Pharmacopoeia (BP), and Chinese Pharmacopiae (CPC).
Formule :C15H23N3O3SDegré de pureté :Min. 95%Masse moléculaire :325.43 g/molLinagliptin impurity G
CAS :Linagliptin impurity G is an impurity in the drug product Linagliptin. It is a natural substance and its CAS number is 668270-11-9. Impurity G can be synthesized from L-phenylalanine and cyclohexane carboxaldehyde in a two step process. The first step involves the reaction of L-phenylalanine with cyclohexane carboxaldehyde to yield methylcyclohexanecarboxylate, which then undergoes hydrolysis to give phenylcyclohexanol. In the second step, phenylcyclohexanol reacts with hydrochloric acid to produce phenylcyclohexanone, which is then oxidized with hydrogen peroxide to yield impurity G. Impurity G can also be found in the pharmacopoeia as a high purity HPLC standard for linagliptin.
Formule :C25H28N8O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :472.54 g/molRef: 3D-FA146003
Produit arrêtéAcarbose Impurity E
CAS :Acarbose Impurity E is an impurity found in acarbose. It is a natural, API impurity and is a synthetic impurity standard. Acarbose Impurity E has been used in drug development research and development, as well as in the HPLC analysis of acarbose to generate a pharmacopoeia-grade purity standard.
Degré de pureté :Min. 95%Simvastatin acid
CAS :Simvastatin acid is the active form of simvastatin, a drug used to lower blood cholesterol levels. Simvastatin acid inhibits HMG-CoA reductase, the enzyme that converts HMG-CoA to mevalonate. This conversion is a rate-limiting step in the synthesis of cholesterol and other lipids. Simvastatin acid binds to polymerase chain and drug transporter proteins, which leads to cell lysis. The concentration–time curve for simvastatin acid is linear and the half-life is approximately 12 hours. When simvastatin acid is administered with drugs that are potent inducers of CYP3A4 or UGT1A1 enzymes, there may be an increased risk for drug interactions. Simvastatin acid has shown no significant human pharmacokinetic interactions with food or grapefruit juice at doses up to 200 mg/day. There are limited data on the pharmacokinetics of simvastatin
Formule :C25H40O6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :436.58 g/mol2-(2-Amino-5-bromobenzoyl)pyridine
CAS :2-(2-Amino-5-bromobenzoyl)pyridine (2ABBP) is a chemical compound with the molecular formula C10H7BrN3. It is a glucuronide conjugate of 2-amino-5-bromobenzoic acid and has been used as an immunological reagent in the form of a monoclonal antibody. 2ABBP binds to dryopteris, which is a plant species that contains polyphenols called pteridines. 2ABBP has been shown to have anti-inflammatory properties in rat liver microsomes and cell culture experiments. The mechanism of action may involve inhibition of cyclooxygenase enzymes, which are involved in prostaglandin synthesis. 2ABBP also binds to human serum albumin and chaperones, proteins that bind other proteins or small molecules. The biological activity of 2ABBP may be due to its ability to form coval
Formule :C12H9BrN2ODegré de pureté :Min. 95%Masse moléculaire :277.12 g/molRef: 3D-IA17613
Produit arrêtéPiperacilloic acid
CAS :Piperacilloic acid is a synthetic compound that exhibits antibacterial activity. It has been shown to be effective against human pathogens, including urothelial carcinoma and human serum. Piperacilloic acid binds to the amino acids lysine and arginine in bacterial proteins and inhibits protein synthesis by inhibiting the function of enzymes that require these amino acids for their activity. The potency of piperacillin is low, but it is activated by hydrolysis in the acidic environment of the stomach or intestinal tract. Piperacilloic acid also has potential as a contraceptive agent because it may inhibit transcriptional regulation of genes that are involved in sperm production.
Formule :C23H29N5O8SDegré de pureté :(Elemental Analysis) Min. 90 Area-%Couleur et forme :PowderMasse moléculaire :535.57 g/molRef: 3D-FP27061
Produit arrêtéSacubitril Impurity 2
CAS :Sacubitril Impurity 2 is a drug product that is an analytical impurity in Sacubitril. This impurity can be found in Sacubitril as a result of natural processes or as an API impurity during the synthesis process. Sacubitril Impurity 2 has been shown to have activity in Metabolism studies, Natural, and Custom synthesis. It has been shown to be a Synthetic impurity standard and HPLC standard. Sacubitril Impurity 2 is used for research and development purposes for the drug development industry, specifically for the niche market. It is also used as an analytical standard for pharmacopoeia methods.
Formule :C24H27NO4Degré de pureté :Min. 95%Masse moléculaire :393.48 g/molRef: 3D-IS181152
Produit arrêté(4-Chlorophenyl)diphenylmethanol
CAS :Please enquire for more information about (4-Chlorophenyl)diphenylmethanol including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C19H15ClODegré de pureté :Min. 95%Masse moléculaire :294.8 g/molTofacitinib dihydro impurity
CAS :Tofacitinib dihydro impurity is a research and development impurity standard for the synthesis of Tofacitinib. It is a custom synthesis with high purity, pharmacopoeia grade, and synthetic. This product is also used in drug development for metabolism studies and analytical applications.
Formule :C16H22N6ODegré de pureté :Min. 95%Masse moléculaire :314.39 g/molRef: 3D-QQC97235
Produit arrêtéN-Desacetyl thiocolchicoside
CAS :N-Desacetyl thiocolchicoside is a white crystalline powder that is soluble in water, methanol and acetone. It has a molecular weight of 320.2 and an empirical formula of C6H14O5. N-Desacetyl thiocolchicoside is used as an analytical standard for HPLC analysis, as a Research and Development (R&D) material for drug development, and as an impurity standard for the manufacture of pharmaceutical products. This compound has been shown to be a metabolite of thiocolchicoside and structurally similar to the drug product chitinase.
Formule :C25H31NO9SDegré de pureté :Min. 95%Masse moléculaire :521.58 g/molDicyclopropylamine hydrochloride
CAS :Dicyclopropylamine hydrochloride is a tyrosine kinase inhibitor that blocks the activity of jak2. It is an innovative molecule with the potential to be used in cancer treatment. Dicyclopropylamine hydrochloride has been shown to inhibit activation of tyrosine kinases, which are involved in cell signaling and proliferation. Dicyclopropylamine hydrochloride also has anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. This drug is not expected to have any toxicity or side effects because it can be easily metabolized by the liver.br>br> Dicyclopropylamine hydrochloride is a white solid with a melting point of 175°C. It has no detectable odor, and it is soluble in water and ethanol. The impurities found in this compound include myristic acid and amines, which can cause inflammatory diseases.br>br> D
Formule :C6H11N•HClDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :133.62 g/mol(S)-Rabeprazole sodium
CAS :(S)-Rabeprazole sodium is an anticancer drug that acts as a kinase inhibitor. It is an analog of Rabeprazole and has been shown to inhibit the growth of cancer cells in vitro and in vivo. (S)-Rabeprazole sodium inhibits the activity of kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. (S)-Rabeprazole sodium has been tested against various types of cancer, including Chinese hamster ovary cells and tumor xenografts in mice. It has also been shown to inhibit elastin degradation, which is important for preventing metastasis of cancer cells. (S)-Rabeprazole sodium may be a promising candidate for the development of new anticancer drugs that target specific kinases and proteins involved in cancer cell growth and survival.
Formule :C18H21N3O3S•NaDegré de pureté :Min. 95%Masse moléculaire :382.43 g/molIvermectin impurity I
CAS :Ivermectin impurity I is an analytical standard that is used for pharmacopoeia and custom synthesis. It is a natural metabolite of the drug Ivermectin, which has been shown to have anti-inflammatory properties in mice. Ivermectin impurity I binds to nicotinic acetylcholine receptors, leading to muscle paralysis and death. This compound is found in high purity for research and development purposes.
Formule :C48H74O14Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :875.09 g/molN-Benzyl albuterol
CAS :N-Benzyl albuterol is a drug product that is custom synthesized to be of high purity with an analytical standard. It is used in research and development, pharmaceutical development, and as a pharmacopoeia or analytical standard. N-Benzyl albuterol has been found to be a metabolite of the drug product Albuterol Sulfate. It is also used in metabolism studies and natural product research. The CAS number for this compound is 24085-03-8.
Formule :C20H27NO3Degré de pureté :Min. 95%Masse moléculaire :329.4 g/molPramipexole EP Impurity C
CAS :Pramipexole EP Impurity C is a synthetic impurity that is used as an impurity standard in the manufacture of Pramipexole EP. It is also used as a research and development tool for drug product, custom synthesis, CAS No. 1973461-14-1, and analytical studies. This compound has been shown to be a metabolite of Pramipexole EP and may have pharmacological properties. Pramipexole EP Impurity C has been found to inhibit the growth of certain bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA) isolates.
Formule :C20H32N6S2Degré de pureté :Min. 95%Ref: 3D-FP165425
Produit arrêtéOxacyclohexane open ring tacrolimus
CAS :Please enquire for more information about Oxacyclohexane open ring tacrolimus including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C44H71NO13Degré de pureté :Min. 95%Masse moléculaire :822.04 g/molRoflumilast Impurity A
CAS :Roflumilast impurity A is a metabolite of roflumilast. It is a drug product that is used as an analytical standard for the determination of roflumilast in HPLC analysis. Roflumilast impurity A is not natural and is synthetic. It has been shown to be a substrate for CYP1A2, CYP2C8, CYP2C9, and CYP3A4 enzymes. Studies have shown that it may be involved in the metabolism of roflumilast through hydroxylation and deamination.
Formule :C16H14Cl2N2O3Degré de pureté :Min. 95%Masse moléculaire :353.2 g/molRef: 3D-IR168438
Produit arrêtéEmpagliflozin S-furanose
CAS :Empagliflozin S-furanose is a Custom synthesis drug product. It is an analytical standard with CAS No. 1620758-32-8, and it is used in research and development of new drugs. Empagliflozin S-furanose has been found to be a metabolite of empagliflozin, a drug that is used to treat type 2 diabetes mellitus. It is also used as an impurity standard for HPLC analysis of empagliflozin because it does not have any biological activity.
Formule :C23H27ClO7Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :450.91 g/molCiprofloxacin ep impurity C
CAS :Ciprofloxacin ep impurity C is a synthetic compound. It is used as a research and development standard in the synthesis of ciprofloxacin. The purity of this compound is high, and it has been tested for metabolism studies. This impurity can be detected by HPLC using an analytical method with a natural reference substance. This impurity has not been evaluated for pharmacopoeia or CAS number.
Formule :C15H16FN3O3Degré de pureté :Min. 95%Masse moléculaire :305.30 g/molDesfluoro ezetimibe
CAS :Desfluoro ezetimibe is a synthetic cholesterol-lowering drug that inhibits intestinal cholesterol absorption. It is chemically synthesized, and the process includes the introduction of fluorine at the 3-position of the C-ring. Desfluoro ezetimibe is not metabolized in humans, but it may be subject to oxidative degradation. The product is also subject to oxidation by light and air, which may result in formation of impurities. The drug substance has been validated as well as its isomers and efficiencies in mass spectrometry detection.
Formule :C24H22FNO3Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :391.43 g/molRef: 3D-FD21193
Produit arrêtéN-Nitroso dorzolamide
N-Nitroso dorzolamide is a chemical compound used as an intermediate in the synthesis of dorzolamide, a carbonic anhydrase inhibitor used in the treatment of glaucoma and ocular hypertension.
Formule :C10H15N3O5S3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :353.44 g/molRocuronium Bromide EP Impurity F Bromide
CAS :Rocuronium Bromide EP Impurity F Bromide is an impurity found in Rocuronium Bromide EP. It is a natural component of the drug product, which is a synthetic drug. The metabolite of this impurity is also found in the natural product, although at much lower concentrations. This impurity has been shown to be present as an analytical impurity in the API and custom synthesis process. This impurity standard has been synthesized synthetically for use in drug development and research and development, as well as for use in HPLC standards.Formule :C34H55N2O4·BrDegré de pureté :Min. 95%Masse moléculaire :635.72 g/molRef: 3D-IR178405
Produit arrêté(3S,4R)-Tofacitinib
CAS :(3S,4R)-Tofacitinib is a rhombic and paramagnetic compound with a Curie point of approximately 10.6°C. It is soluble in nonpolar solvents such as benzene and toluene. (3S,4R)-Tofacitinib has been shown to have magnetic properties that are dependent on the temperature and the frequency of the applied magnetic field. The paramagnetic resonance spectra were observed at 18°C and 32°C, while the paramagnetic resonance spectrum was observed at -2°C. The octahedral interactions are likely due to the presence of six different types of iron ions in the crystal structure.
Formule :C16H20N6ODegré de pureté :Min. 95%Masse moléculaire :312.37 g/molRef: 3D-STB57848
Produit arrêté3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride
CAS :3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride is a versatile compound with various characteristics and applications. It has been found to have diverse effects on different biological processes. This compound has shown potential as an antimuscarinic agent, which means it can block the action of acetylcholine at muscarinic receptors in the body.
Formule :C19H25ClN2O2Degré de pureté :Min. 95%Masse moléculaire :348.9 g/molChlorthalidone impurity E
CAS :Chlorthalidone impurity E is an analytical standard for the HPLC analysis of chlorthalidone in pharmaceutical drug products and is a metabolite of chlorthalidone. Chlorthalidone impurity E is an API impurity that can be found in the synthesis of chlorthalidone, and it has been detected as a minor component in certain drug products. It is important to have an accurate specification for this compound, since it can affect the pharmacological properties of the drug product. The purity level of this compound must be at least 98% or greater to ensure that there are no contaminants present. This compound is also a metabolite of chlorthalidone and is used as a pharmacopoeia reference substance for testing equipment calibration.END>
Formule :C14H11ClN2O3SDegré de pureté :Min. 95%Masse moléculaire :322.77 g/molTriethylene glycol flufenamate
CAS :Etofenamate impurity
Formule :C20H22F3NO5Degré de pureté :Min. 95%Couleur et forme :Clear LiquidMasse moléculaire :413.39 g/molD-6-Cyano-6-norlysergic acid methyl ester
CAS :Please enquire for more information about D-6-Cyano-6-norlysergic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C17H15N3O2Degré de pureté :Min. 95%Masse moléculaire :293.32 g/molGS 441524 triphosphate
CAS :Triphosphorylated form of an antiviral nucleoside analog with activity against zoonotic feline infectious peritonitis virus (FIPV) and severe acute respiratory syndrome (SARS) virus from Coronaviridae family. The compound is the biologically active form of the GS 441524 prodrug and being triphosphorylated, it competes with natural nucleoside triphosphates in cells and interferes with viral RNA synthesis. Made to order.
Formule :C12H12N5O13P3·4NaDegré de pureté :(31P-Nmr) Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :531.20 g/molAtorvastatin calcium trihydrate EP Impurity G
CAS :Atorvastatin is a drug that belongs to the class of statins. It is used for the treatment of high cholesterol levels and other related diseases, such as cardiovascular disease. Atorvastatin calcium trihydrate EP Impurity G is an impurity that may be present in atorvastatin calcium trihydrate. This compound has not been found to have any pharmacological activity.
Formule :C34H37FN2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :572.67 g/molRef: 3D-IA182820
Produit arrêté
