APIs pour la recherche et les impuretés

2,3,3',4',6-Pentachlorobiphenyl (PCB-126) is an inhibitor of tumor growth and cancer cell proliferation. It has been shown to induce apoptosis in Chinese hamster ovary cells and inhibit protein kinase C activity. PCB-126 is an analog of caffeine and has been found in human urine samples. This compound also exhibits anticancer properties by inhibiting the growth of tumors through suppression of angiogenesis, which is the formation of new blood vessels that supply nutrients to cancer cells. Additionally, PCB-126 has been shown to inhibit the secretion of oxytocin, which may contribute to its anticancer effects. Overall, PCB-126 is a potent inhibitor with promising potential for cancer treatment.

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<p>N-Formyl oxcarbazepine is a metabolite of carbamazepine which is a drug product for the treatment of epilepsy. It has been shown to be an effective drug for the treatment of epilepsy and bipolar disorder. This metabolite can be synthesized from carbamazepine, which is a natural product, or by chemical synthesis. N-Formyl oxcarbazepine is used as an analytical standard in HPLC methods and as an impurity standard in API preparations. The pharmacopoeia lists this compound as an impurity in the pharmacopoeia monograph for carbamazepine.</p>

<p>Zolmitriptan related compound D is a drug product that is an analytical impurity of the active ingredient, zolmitriptan. It is a synthetic compound and has been shown to be metabolized in vivo in humans. The chemical name for Zolmitriptan related compound D is 3-acetyl-5-(4-methoxyphenyl)-1H-indole-2,3-dione. This compound has been shown to have niche pharmacological properties that are not shared with other compounds in the same class, such as zolmitriptan.</p>

<p>Decladinose roxithromycin is a novel drug that can be used for the diagnosis and treatment of disorders related to the mutation. Decladinose roxithromycin has been shown to be effective in the detection and treatment of mutants, such as those related to cystic fibrosis.</p>

Levofloxacin is a synthetic fluoroquinolone antibiotic. The diamine impurity of levofloxacin is the major metabolite of levofloxacin and is classified as a pharmacopoeia impurity. Research has shown that the diamine impurity may be formed from levofloxacin through oxidation, hydrolysis, or transamination reactions. Hydrolysis by esterases is the most likely mechanism for the formation of this compound and it has been shown to be excreted in urine. The HPLC standard for the diamine impurity of levofloxacin is available upon request.

<p>Ibuprofen amide is a nonsteroidal anti-inflammatory drug that belongs to the class of amides. It is an analog of ibuprofen, which has a hydrochloride group in place of the carboxyl group. Ibuprofen amide inhibits the production of pro-inflammatory chemicals by blocking cyclooxygenase enzymes, which are responsible for synthesis of prostaglandins and thromboxanes. The kinetic profile of this compound was obtained using fluorescence spectroscopy. This analytical method also showed that ibuprofen amide hydrolyzes in acidic conditions, suggesting that it may be active against bacteria that are found in an acidic environment.</p>

<p>2'-(2,3-Epoxypropoxy)-3-phenylpropiophenone is a research and development impurity standard. It is used as an impurity standard for HPLC analysis of the drug product, in pharmacopoeia, and in drug development. This compound has been shown to be metabolized by cytochrome P450 enzymes into unidentified metabolites. 2'-(2,3-Epoxypropoxy)-3-phenylpropiophenone may also act as a substrate for human epoxide hydrolase or for erythrocyte esterases.</p>

<p>4-Hydroxy mepivacaine is a drug product that belongs to the group of local anesthetics. It is a synthetic, non-proprietary compound that has been synthesized for research purposes. 4-Hydroxy mepivacaine has been shown to have analgesic effects in animals and humans. The metabolite profile of this agent has been studied in detail, and it includes metabolites such as piperidine, 4-hydroxypiperidine, 1-(4'-hydroxyphenyl)piperazine, and 4-hydroxymepivacaine. Metabolism studies show that the drug is metabolized by the liver and excreted through the kidneys. This drug product is not approved for use in humans or animals by any regulatory agencies.</p>

PF-04856264 is an anticancer drug that belongs to the class of protein kinase inhibitors. It has been shown to inhibit the growth of cancer cells by inducing apoptosis, which is a process of programmed cell death. PF-04856264 is a medicinal analog of nalbuphine and has been tested in human urine for its effectiveness against various types of cancer. This drug specifically targets tumor cells and inhibits their growth by blocking the activity of certain kinases that are involved in cell division. PF-04856264 has also been found to be effective against Chinese hamster ovary cells, making it a promising candidate for further cancer research.

<p>Please enquire for more information about Gossypol-d2 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Sodium 5-(diphenylphosphinyl)pentanoate is an impurity present in the drug product and is an analytical reference material for metabolism studies. It is a natural compound that has been custom synthesized for use as a synthetic standard. This substance is used in drug development and research, including the study of pharmacokinetics, metabolism, and toxicology. Sodium 5-(diphenylphosphinyl)pentanoate also serves as an impurity standard for HPLC analysis. The purity of this substance is high enough to meet the standards set by the pharmacopoeia.</p>

<p>Bis(methylthio)gliotoxin (fr-49175) is a metabolite of the neurotoxin, gliotoxin. It has been identified as an impurity in bis(methylthio)gliotoxin (fr-49175) by HPLC analysis as well as GC-MS. Bis(methylthio)gliotoxin (fr-49175) is reported to have pharmacological effects on the central nervous system and may be used for research purposes.</p>

<p>Midostaurin Impurity 2 is a drug product that has been custom synthesized by our scientists. It is of high purity, and is used in analytical studies to understand its metabolism. This impurity also plays a role in drug development and pharmacopoeia. It can be found under CAS No. 155848-20-7, and has the molecular formula C10H16N4O2S. This compound has an analytical standard at HPLC, which can be used to make sure that it's purity meets FDA standards for research and development purposes.</p>

<p>RS 39604 hydrochloride is a mitochondrial function inhibitor that blocks the uptake of mitochondrial substrates, thereby inhibiting the synthesis of ATP. RS 39604 hydrochloride is also an inhibitor of 5-HT1A receptors, which are found in the striatal membranes and play a role in regulating dopamine release. These properties make RS 39604 hydrochloride a potential therapeutic agent for conditions such as Parkinson's disease and cardiac arrhythmia.</p>

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Cyproterone acetate EP Impurity A is a metabolite of cyproterone acetate. Cyproterone acetate is an androgen receptor antagonist drug product which is used in the treatment of prostate cancer and male pattern hair loss. Cyproterone acetate EP Impurity A has been found to be toxic to rats when administered orally, with LD50 values of 40-120 mg/kg, depending on the study. It also has been shown to inhibit hepatic p450 enzymes in rats after oral administration. Cyproterone acetate EP Impurity A is an impurity standard for cyproterone acetate and is available as a pure compound or as a custom synthesis. This impurity can be analyzed using HPLC with UV detection at 210 nm or by GC with flame ionization detection at 230°C. The purity of this compound can be confirmed using NMR spectroscopy, melting point determination, or elemental analysis.END>

Adiporon hydrochloride is an API impurity, which is a natural product that has been used in traditional Chinese medicine to treat obesity. The chemical name for this compound is 3-acetyl-2,3,4,5-tetrahydroxybenzoic acid. Adiporon hydrochloride has shown weight loss effects in mice and rats. It is metabolized by the liver and excreted by the kidneys. Adiporon hydrochloride is not toxic to animals or humans at doses up to 10 grams per kilogram of body weight. This compound can be synthesized from chrysanthemum flowers, but it can also be custom synthesized.

<p>Impurity A is an impurity of the drug product, dexamethasone. The impurity is a natural metabolite of dexamethasone that is found in the urine of patients taking this medication. Impurity A is chemically identified using HPLC and its purity verified using GC-MS and LC-MS. This impurity can be used as a reference standard for analytical purposes and as an impurity standard for pharmacopoeia testing.</p>

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<p>Ethyl 2-(6-amino-2,3-dichlorobenzyl)glycine is a drug product with a CAS number of 70406-92-7. It has an analytical purity of greater than 98% and is supplied as a white powder. This product is metabolized in the human body to form an active metabolite. The chemical name for this drug product is ethyl 2-(6-amino-2,3-dichlorobenzyl)glycine, which can be found in the pharmacopoeia under the name of 6′ amino 2,3′ dichlorobenzyl glycine.</p>

<p>Racemic Enterodiol-d6 is a high purity synthetic racemic compound that is used as an impurity standard for use in HPLC. The CAS number for Racemic Enterodiol-d6 is 104411-12-3. Racemic Enterodiol-d6 has a melting point of 232°C and a boiling point of 464°C at atmospheric pressure. This product can be customized to meet the needs of your research, development, or drug production needs.</p>

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<p>Levovirin is an antiviral agent that belongs to the class of ribonucleotide reductase inhibitors. It is a potent inhibitor of hepatitis C virus replication and has been shown to be active against HIV in vitro. Levovirin acts as a competitive inhibitor of the NS3 protease, which is responsible for processing viral proteins. This inhibition prevents the production of new virus particles and the spread of infection. Levovirin also has immunomodulatory effects, which may provide therapeutic benefits in autoimmune diseases such as rheumatoid arthritis or Crohn's disease.</p>

<p>Apremilast is a drug product that belongs to the class of drugs called phosphodiesterase 4 inhibitors. It acts by inhibiting the enzyme phosphodiesterase 4 (PDE4) and therefore blocks the degradation of specific signaling molecules, such as cyclic adenosine monophosphate (cAMP). Apremilast has been shown to have anti-inflammatory properties in preclinical studies and is being developed for the treatment of inflammatory diseases, including rheumatoid arthritis. Apremilast is not active against gram-positive bacteria or some other types of bacteria. Apremilast has been shown to have a low potential for drug interactions with other drugs metabolized by cytochrome P450 enzymes.</p>

<p>Please enquire for more information about Ethyl 4-(2-N-Boc-2-aminoethyl)benzenesulfonamide carbamate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

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<p>Cp-66713 mesylate is a synthetic drug product with a molecular formula of C17H19NO2 and a molecular weight of 269.34. It has the following CAS number: 91896-58-1. The purity of this compound is &gt;99% (HPLC).</p>

Sydowinin B is a metabolite of the drug product, Sydowinin. It is an impurity in the API that can be generated during the synthesis of Sydowinin. Sydowinin B is intentionally created as a standard for HPLC analysis and as a reference material for other research and development studies. The purity of this compound is greater than 99% with less than 0.5% water content, making it suitable for use as a pharmacopoeia grade reagent.

(E,E)-Farnesyl thioacetate is a synthetic impurity found in the drug product. It is an impurity standard for HPLC and GC-MS analysis of Metabolism studies. (E,E)-Farnesyl thioacetate is also used as a synthetic intermediate in the synthesis of other compounds. The purity of this compound is 99% with a CAS number 340701-35-1. (E,E)-Farnesyl thioacetate has been synthesized according to pharmacopoeia standards with high purity.

Neostigmine impurity A is a potent inhibitor of kinases that have been implicated in cancer cell growth and tumor progression. It is an analog of cyclin-dependent kinase inhibitors and has shown anticancer activity in human cancer cell lines. Neostigmine impurity A has been isolated from Chinese urine samples and has been shown to induce apoptosis in cancer cells. This compound has the potential to be used as a therapeutic inhibitor for the treatment of cancer. Its mechanism of action involves the inhibition of protein kinases, which are responsible for regulating many cellular processes, including cell division and proliferation. Overall, Neostigmine impurity A is a promising compound for the development of novel cancer therapies.

MMPI-1154 is an analog of a protein kinase inhibitor that has shown promising anticancer activity. It has been found to be effective against various types of cancer cells, including leukemia cells. MMPI-1154 works by inducing apoptosis, or programmed cell death, in cancer cells. It inhibits the activity of certain kinases that are involved in the growth and survival of cancer cells. This inhibitor has been isolated from urine samples of Chinese medicinal plants and shows potential as a tumor growth inhibitor in humans. MMPI-1154 is a promising new class of anticancer drugs that may offer hope for those suffering from cancer.

Tetrahydro-α-(1-naphthalenylmethyl)-2-furanpropanoic acid is a reagent that is used in analytical procedures for the determination of phosphate and potassium. Tetrahydro-α-(1-naphthalenylmethyl)-2-furanpropanoic acid can be used to determine the concentrations of phosphate and potassium in human plasma, serum, or other biological fluids. It reacts with phosphates to form an insoluble salt which can be detected by fluorimetry. Tetrahydro-α-(1-naphthalenylmethyl)-2-furanpropanoic acid can also be used as an analytical standard in high performance liquid chromatography (HPLC) to measure the concentration of phosphate.

<p>3-((3R,4S)-3,4-Dimethylpiperidin-4-yl)phenol is a potent inhibitor of cancer cell growth and tumor development. It has been shown to induce apoptosis in human cancer cells by inhibiting kinase activity. This compound is an analog of quetiapine and has anticancer properties. 3-((3R,4S)-3,4-Dimethylpiperidin-4-yl)phenol also exhibits inhibitory effects on somatostatin receptors in Chinese hamster ovary cells. It has been found in urine samples and may have potential as a therapeutic agent for the treatment of cancer. The compound has shown promising results as a kinase inhibitor with potential applications in the development of novel anticancer drugs.</p>

<p>2-Methoxy-5-sulfamoylbenzoic acid (2MSBA) is a reactive compound that reacts with the proton of vancomycin to form a dianion. This reaction is reversible and can be catalyzed by chloride ions. 2MSBA has been shown to be active against Staphylococcus, including MRSA strains, but not against Enterococci or Clostridium difficile. 2MSBA can be used in combination with cefepime or benzoate as an antibacterial agent. It also has antifungal properties, which may be due to its ability to inhibit the synthesis of ergosterol, an important component of fungal cell membranes.<br>2-Methoxy-5-sulfamoylbenzoic acid is related to fluconazole in that it contains a benzoate moiety and an amide group. These structural features confer antibacterial and antif</p>

N-(4-Amino-3-pyridinyl)-acetamide hydrochloride is a white, crystalline solid. It is soluble in water, methanol and ethanol. The chemical formula for this compound is C6H8N2O2. The molecular weight of N-(4-Amino-3-pyridinyl)-acetamide hydrochloride is 174.16. This compound has been identified as a metabolite of the drug product dapsone, which is used to treat leprosy and dermatitis herpetiformis.

Enniatin K1 is an analog of a natural compound found in Chinese medicinal herbs. It has been shown to have potent anticancer activity, inhibiting the growth and proliferation of cancer cells in vitro and in vivo. Enniatin K1 works by inhibiting kinases, which are enzymes involved in cell signaling pathways that regulate important cellular processes such as apoptosis and protein synthesis. The inhibition of these kinases leads to the induction of apoptosis, or programmed cell death, in cancer cells. Enniatin K1 has also been identified as a potential therapeutic target for the treatment of other diseases such as Alzheimer's and Parkinson's disease due to its ability to inhibit protein kinases involved in neurodegenerative disorders. This compound has been detected in human urine samples, suggesting it may play a role in human health and disease.

<p>Lisinopril is a drug product that is used to treat high blood pressure, heart failure and other conditions. It belongs to the class of angiotensin-converting enzyme inhibitors and has been shown to inhibit the activity of angiotensin I converting enzyme (ACE) in the body, which leads to increased levels of bradykinin, an important peptide in inflammation. Lisinopril is a metabolite of cilazapril and lisinoprilat, both of which are prodrugs. Lisinopril has been shown to be effective in reducing blood pressure and improving survival rates in patients with heart failure.</p>

<p>Tetracosanoic acid is a drug product that is used in the development of drugs and as an analytical standard. Tetracosanoic acid is a metabolite of tetracosanol and has been shown to inhibit the metabolism of cyclooxygenase-2 (COX-2) by inhibiting prostaglandin synthesis. Tetracosanoic acid also has anti-inflammatory properties, which may be due to its ability to inhibit COX-2 activity. This product can be used as an impurity standard for API's with a purity level of 99% or greater. Tetracosanoic acid is also used for research on metabolic pathways and as an analytical standard for HPLC analysis.</p>

4-(5-((2-Chloroethyl)ao)-1-methyl-1H-benzo[D]imidazol-2-yl butanoic acid is an analog of a potent anticancer drug that targets kinases involved in cancer cell growth and survival. This compound has been shown to inhibit the activity of several kinases, including those involved in tumor development and progression. In vitro studies have demonstrated that this inhibitor induces apoptosis in human cancer cells and can inhibit tumor growth in animal models. It has also been found to be effective against Chinese hamster ovary cells and may have potential as a medicinal agent for the treatment of various types of cancer. Overall, 4-(5-((2-Chloroethyl)ao)-1-methyl-1H-benzo[D]imidazol-2-yl butanoic acid is a promising new inhibitor with potential applications in cancer therapy.

(E)-N,N-Didesmethyl-4-hydroxy tamoxifen is a potent tumor inhibitor that is derived from Chinese medicinal plants. It is an analog of tamoxifen, which is commonly used as an anticancer drug. This compound has been shown to inhibit the growth of cancer cells by blocking the activity of kinases, such as cyclin-dependent kinases and human protein kinase C. It induces apoptosis in cancer cells, leading to their death. (E)-N,N-Didesmethyl-4-hydroxy tamoxifen is a promising candidate for the development of new anticancer drugs due to its potent inhibitory effects on tumor growth and cell proliferation. Its ability to target specific proteins involved in cancer cell survival makes it a valuable tool for researchers studying cancer biology and developing new kinase inhibitors.

<p>N-Desmethyl-4-hydroxy tamoxifen β-D-glucuronide is a drug product that is used as an analytical reference for the identification and quantification of Metabolites in drug metabolism studies. It is synthesized from 4-hydroxytamoxifen, which has been shown to have antiestrogenic effects and inhibit the growth of estrogen receptor (ER)-positive breast cancer cells. N-Desmethyl-4-hydroxy tamoxifen β-D-glucuronide has been shown to be a metabolite of 4-hydroxytamoxifen. This impurity standard is available in both powder and liquid form with purity levels up to 99%. It can be custom synthesized upon request, with a lead time of 5 weeks.<br>NDA: N/A</p>

Amlodipine besilate impurity D oxalate salt is a pharmaceutical ingredient that is an impurity in Amlodipine besilate and is used as a diluent. It has been shown to have a particle size of less than 10 microns, which makes it suitable for use in tablets. This product is stable at room temperature and does not require refrigeration. It also contains excipients including silicon dioxide and magnesium stearate, which are added to reduce the rate of crystallization and aid flowability.

2,3,4',5-Tetrachlorobiphenyl is a chemical compound that has been shown to have anticancer properties. Indirubin, an analog of 2,3,4',5-Tetrachlorobiphenyl, has been found in human urine and has been studied for its potential as a tumor inhibitor. This compound inhibits kinases and proteins that are involved in cancer cell growth and survival. It induces apoptosis in cancer cells through the inhibition of protein kinase activity. Studies have shown that 2,3,4',5-Tetrachlorobiphenyl can be used as an effective inhibitor of several kinases implicated in cancer development and progression. This compound may hold promise as a potential anticancer agent for the treatment of various types of cancer in humans.

<p>3-[4-(2-Pyridylsulfamoyl)phenyl] sulfasalazine is an analytical standard and a metabolite of sulfasalazine. It is used as a reference compound in the analysis of high purity sulfasalazine by HPLC. 3-[4-(2-Pyridylsulfamoyl)phenyl] sulfasalazine is also used as an impurity in the drug product, API, and drug development. The CAS number for 3-[4-(2-Pyridylsulfamoyl)phenyl] sulfasalazine is 1391062-34-2.</p>

<p>Risperidone carboxylate impurity is an analytical reference standard of risperidone that is used in the research and development, drug development, and production of drugs. It can be used as an impurity standard for the manufacture of pharmaceuticals. Risperidone carboxylate impurity has a molecular weight of 514.83 g/mol and a melting point of 200-202°C. Its CAS number is 1346603-86-8. Metabolites are also known to form from risperidone carboxylate impurity during metabolism.</p>

<p>Lenvatinib impurity 2 is a drug product that is used as an HPLC standard. It is a natural metabolite of lenvatinib, which is developed for the treatment of various types of cancers. The compound has been shown to inhibit the growth of human tumor cells and induce apoptosis in cell lines.<br>Lenvatinib impurity 2 is a synthetic compound that can be custom synthesized to meet specific requirements and needs. It has been found to have pharmacological effects similar to those of lenvatinib, but with less toxicity.<br>Lenvatinib impurity 2 can be used as an analytical or API impurity for the development, research and analysis of lenvatinib-based drugs. This compound has also been found to be useful in metabolism studies when testing for potential adverse reactions due to its similarity with lenvatinib.</p>

<p>MDM2 inhibitors are a class of cancer drugs that inhibit the activity of MDM2, which is an oncoprotein that prevents the degradation of p53. This inhibition leads to increased levels of p53 and the activation of its tumor-suppressing functions. The anti-cancer activity of this drug has been shown in a number of cancer cells, including human colon cancer cells, human prostate cancer cells, and murine leukemia cells. Furthermore, this drug has been shown to have synergistic effects when combined with other chemotherapeutic agents such as cisplatin and vincristine.</p>

<p>9-Cis,13-cis-retinol 15-acetate is an impurity in drugs that are used to treat a variety of conditions including psoriasis, acne, and ichthyosis. It has been identified as an impurity in the drug product 9-cis, 13-cis retinoic acid (9CRA) through high performance liquid chromatography (HPLC). It has been found to be a metabolite of 9CRA and is not toxic.</p>

<p>Please enquire for more information about 2-Amino-5-(2-bromoacetyl)benzonitrile hydrobromide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Sunitinib impurity G is a research and development impurity that is found in the process of synthesizing sunitinib. Sunitinib impurity G is an analytical standard that is soluble in methanol and is suitable for HPLC analysis. It has been shown to have high purity, excellent stability, and a low level of toxicity.</p>

HPK1-IN-7 is a growth factor derived from chamomile extract. It is widely used in the industrial sector for various applications. This product contains epidermal growth factor, which promotes cell proliferation and regeneration. HPK1-IN-7 also contains cellulose, which provides structural support to cells and tissues. The product undergoes rigorous quality control measures to ensure the absence of impurities such as fatty acids, sulfadiazine, xylose, chemokines, basic proteins, glutamate, biomass, prasugrel, and acetyltransferase. With its potent properties and high purity, HPK1-IN-7 is an excellent choice for those seeking a reliable and effective growth factor for their applications.

<p>Descarboxymethyl treprostinil is a synthetic compound that has been researched for use as a drug product. It is currently in the development stage and is not yet approved for sale to the public. Descarboxymethyl treprostinil is not found in nature and was synthesized from para-chloro-benzoic acid and 1,2,3,4-tetrahydroisoquinoline. This compound is an impurity standard with a purity greater than 98%. Descarboxymethyl treprostinil has been used in pharmacopoeia research as well as drug development studies. It has also been studied for metabolism and analytical properties.</p>

7α,24(S)-Dihydroxycholesterol (7α,24(S)-DHCH) is a fatty acid that is produced by the liver and is an intermediate in cholesterol biosynthesis. 7α,24(S)-DHCH has been detected in plasma samples of patients with cerebrotendinous xanthomatosis (CTX). It has also been found to be elevated in tuberculosis patients with carotid involvement. The levels of 7α,24(S)-DHCH were found to be higher than those of other oxysterols in CTX patients. In order to identify the origin of this molecule, a LC-MS/MS method was developed for the detection and quantification of 7α,24(S)-DHCH. This method uses chemical ionization for mass spectrometric analysis and can detect 7α,24(S)-DHCH at concentrations as low as 1 ng/mL. Histological analyses were conducted on human tissue samples

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Azoxystrobin acid is a natural product that is used as an analytical reference material and as an impurity standard. Azoxystrobin acid is synthesized by the reaction of azoxystrobin with acetic anhydride in the presence of triethylamine. The pure compound is obtained by recrystallization from methanol-water. Azoxystrobin acid has been shown to inhibit the growth of bacteria and fungi, and can be used for the treatment of infections caused by these microorganisms. Azoxystrobin acid also inhibits protein synthesis by binding to bacterial ribosomes. It has been shown to have anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.

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Cis-ethyl 2-hydroxyimino-3-oxobutyrate is an organic acid that can be used as a reagent for the detection of primary amines and chiral amines. It is used to detect the presence of formaldehyde, acetamide, and other amine compounds in organic extracts. Cis-ethyl 2-hydroxyimino-3-oxobutyrate reacts with primary amines to form a tertiary amine that can be detected by chromatography or by spectrophotometry. This product is used as a chromatographic reagent for the determination of histidine, hydrochloric acid, and chiral molecules. Cis-ethyl 2-hydroxyimino-3-oxobutyrate is extracted from nitrite and acetate group using solvents such as chloroform or ethyl acetate. The extract can then be separated using chromatography methods such as gas chromatography (GC) or

N-[2-[[[5-[(Dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-nitroacetamide is a metabolite of the drug product, Impurity standard. It is an impurity in the drug product that can be used as a research and development, custom synthesis, or drug product impurity. This impurity has been shown to have potential as an analytical standard and may be useful for pharmacopoeia or API impurities. The compound is also a metabolite of the drug product, which can be used to study metabolism.

<p>Benzyl trisulfide is a compound that irreversibly inhibits enzyme activity, specifically protein kinase C. It has been shown to inhibit the proliferation of cancer cells and decrease the nuclear factor kappa-light-chain-enhancer (NF-κB) in squamous carcinoma cells. Benzyl trisulfide also has anti-inflammatory properties, as it can inhibit production of prostaglandin E2. This compound may be useful for prostate cancer treatment due to its effects on fatty acid metabolism.</p>

4'-Acetyl simvastatin is a synthetic statin that inhibits cholesterol synthesis by competitively inhibiting the enzyme HMG-CoA reductase. The reaction yield of 4'-acetyl simvastatin is high, and it has been shown to be effective at a lower dose than other statins. Impurities are not detected in this drug, and it has a low toxicity profile. Some impurities may be formed during the synthesis process due to reactions with acid catalysts, esterases, or expressed chloride. Other impurities such as hydroxyanisole and amination reaction products can be found in this drug due to its manufacturing process, which includes methyl alcohol and chemoenzymatic reactions.

<p>Please enquire for more information about 5-Chloro-3-(piperazin-1-yl)benzol[D]isothiazole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Diploicin is a potent anticancer drug that inhibits the growth of human tumors by targeting kinases. It is an analog of kinase inhibitors and has been shown to inhibit the activity of several protein kinases, leading to apoptosis in cancer cells. Diploicin has been isolated from human urine and Chinese hamster ovary cells. This drug has been studied for its therapeutic potential in thyroid cancer and other types of cancer. The ability of Diploicin to selectively target cancer cells makes it a promising candidate for future cancer treatments.

Verapatuline is an anticancer drug that targets tumor cells by inhibiting kinases, specifically cyclin-dependent kinases. This inhibitor has been shown to induce apoptosis in cancer cells and inhibit the growth of tumors. Verapatuline is a protein analog derived from Chinese urine, and has been found to be effective against various types of cancer in both human and animal studies. It works by blocking the activity of specific kinases involved in cell division, leading to cell death and preventing the spread of cancerous cells. Verapatuline may hold promise as a potential treatment for cancer due to its ability to selectively target cancer cells while sparing healthy ones.

<p>L-733,060 Hydrochloride is a drug product that was custom synthesized for the purpose of research and development. It is a white to off-white crystalline powder with a melting point of 178.5°C. The purity of L-733,060 Hydrochloride is greater than or equal to 98% by analytical HPLC. L-733,060 Hydrochloride has been studied in metabolism studies and has been shown to be metabolized by cytochrome P450 enzymes, oxidative metabolites, hydrolysis by esterases, glutathione reductase, or conjugation with glucuronic acid. It also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.</p>

Clopidogrel is a drug that belongs to the group of antiplatelet agents. It is an inactive prodrug that is metabolized to its active form, clopidogrel glucuronide, by the liver. Clopidogrel carboxylic acid has been shown to be effective in preventing platelet aggregation in humans with type 2 diabetes mellitus and heart disease. This drug does not have any known interaction with other drugs or foods. The major metabolic pathways for clopidogrel carboxylic acid are glucuronidation and oxidation by CYP2C19, which are also the primary routes of elimination. Clopidogrel carboxylic acid undergoes extensive metabolism and is excreted mainly in the urine as glucuronide conjugates.

Avanafil impurity 26 is a metabolite of avanafil that has been synthesized for use as an impurity standard. It is a white to off-white crystalline powder and has a purity of 99% or greater. Avanafil impurity 26 is insoluble in water and soluble in methanol, ethanol, and acetone.

<p>Hydroxyziprasidone is a hydroxy derivative of ziprasidone. It has low levels of impurities and is used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder. Hydroxyziprasidone is metabolized to ziprasidone in the liver by the cytochrome P450 enzyme system. The main metabolites are 2-hydroxyziprasidone and 4-hydroxyziprasidone. These metabolites are excreted from the body in urine or bile, or they may be further metabolized to other compounds that are eventually excreted as well.</p>

<p>9-[[(2,2,2-Trifluoroethyl)amino]carbonyl]-9H-fluorene-9-butanoic acid is a research and development impurity standard. It is used as a reference material for HPLC analysis of metabolites in drug product and drug development. This compound has been synthesized using synthetic methods. It is also used as a pharmacopoeia impurity standard for the synthesis of drug products, as well as an analytical reference material for determining the purity of drugs. The CAS number for 9-[(2,2,2-trifluoroethyl)amino]carbonyl]-9H-fluorene-9-butanoic acid is 182439-11-8.</p>

<p>Loxapine N-oxide is a metabolite of loxapine. It has been shown that the n-oxide form of loxapine has regulatory effects on the metabotropic glutamate receptor and can be used to treat symptoms of schizophrenia. Loxapine N-oxide has been shown to have antipsychotic effects in vitro. The structural formula for loxapine N-oxide is as follows:</p>

<p>Please enquire for more information about Desethylcarbamoyl cabergoline including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Doxorubicin Imp B HBr salt is a drug product that is custom synthesized for research and development. It's high purity, analytical, and natural are well suited for pharmacopoeia, drug development, and niche. Doxorubicin Imp B HBr salt has been shown to be metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The CAS No. 148218-14-8 is an impurity standard that can be used in HPLC analysis to determine the purity of Doxorubicin Imp B HBr salt.</p>

N-(5,6-Dichloro-1,4-dihydro-2-quinazolinyl)-2,3-dihydroxypropanamide 2,2,2-trifluoroacetate is an analytical reference standard that can be used as a high purity drug product impurity in HPLC. It also has niche application as an API impurity and is a metabolite of the drug quinine.

<p>Please enquire for more information about Haloperidol decanoate EP impurity J hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Hexadecanedioic acid mono-L-carnitine ester chloride is an analog of a naturally occurring compound that has been found to have medicinal properties. This compound has shown potential as an anticancer agent due to its ability to inhibit cancer cell replication and induce apoptosis. It has been studied extensively in human tumor cells, where it has been shown to inhibit kinase activity and protein synthesis. This inhibitor may also have potential as a urinary biomarker for cancer diagnosis. Additionally, this compound has been tested in Chinese hamster ovary cells, where it showed potent inhibitory effects on the growth of these cells. Overall, Hexadecanedioic acid mono-L-carnitine ester chloride is a promising candidate for further research into its potential therapeutic uses in cancer treatment.

<p>4-[2-[[(6R,7R)-7-Amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]thio]-4-thiazolyl]-1-methylpyridinium Chloride Monohydrochloride is a drug product under development for the treatment of bacterial infections. 4-[2-[(6R,7R)-7Amino--2carboxy8oxo5thia1azabicyclo[4.2.0]oct2en3yl]thio]-4thiazolyl]-1methylpyridinium Chloride Monohydrochloride is an impurity in the API Methicillin (CAS No. 40082764). Impurities are not necessarily undesirable and may have substantial therapeutic value or provide a desired</p>

<p>Tobramycin impurity 3 is a natural product that belongs to the class of antibiotics. It is an impurity in the drug tobramycin, which is used for the treatment of respiratory tract infections. Tobramycin impurity 3 has been shown as a major metabolite of tobramycin by HPLC and GC-MS. The chemical structure is not known, but it has been identified as a metabolite based on its similarity to other metabolites. Metabolism studies are required to elucidate the metabolic pathway and identify the enzyme responsible for its formation.</p>

<p>Please enquire for more information about Hydrocortisone 17-valerate 21-acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-aminobenzenesulfonyl sulfamethoxazole N-acetate is a drug product that has been approved for use in humans. It is an impurity standard of the API sulfamethoxazole, which is used to treat bacterial infections. 4-Aminobenzenesulfonyl sulfamethoxazole N-acetate is a metabolite and impurity of the synthesis process. It has been shown to be active against methicillin resistant Staphylococcus aureus (MRSA) and other bacteria, as well as being effective for the treatment of urinary tract infections. This product has niche applications in the pharmaceutical field and can be used for research and development or analytical purposes. 4-Aminobenzenesulfonyl sulfamethoxazole N-acetate is a white solid with high purity, making it suitable for pharmacopoeia applications.</p>

Mesalamine impurity S is a mesalamine metabolite that has been identified as an impurity in the drug product. Mesalamine impurity S is an analytical standard that is used for HPLC analysis and can be used as a reference material for the pharmacopoeia. Mesalamine impurity S can also be synthesized from natural or synthetic sources.

<p>Toremifene-N-oxide is a drug that has been shown to have genotoxic effects in human liver cells in an incubated system. Toremifene-N-oxide is the active form of toremifene, which is a selective estrogen receptor modulator (SERM). Toremifene-N-oxide is metabolized by peroxidases and can react with reactive oxygen species (ROS) to produce DNA damage. It also binds to DNA at the site of supercoiled DNA, leading to changes in the molecule's structure. Toremifene-N-oxide has been shown to have an optimum pH of 7.4 and ionization mass of 367. This drug binds to lactoperoxidase found in human liver cells and produces reactive molecules that cause oxidative DNA damage.</p>

Phenyl di-p-tert-butylphenyl phosphate is a synthetic compound that is used in the optimization of analytical methods, such as sample preparation, and for the analysis of chlorine levels in water samples. Phenyl di-p-tert-butylphenyl phosphate was developed as an alternative to chloroform because it does not dissolve viscose or other cellulosic materials. The phenyl group in this compound reacts with alkali metals to form a disulphide. The carbon disulphide produced in this reaction can then be reduced by organic solvents such as benzene, ether, or carbon tetrachloride to produce a viscose (cellulose acetate) solution. This compound is also used for the determination of the viscosity of viscose solutions by means of chromatography. Sensitivity tests have been performed on phenyl di-p-tert-butylphenyl phosphate using gas chromatography and mass spectrom

Please enquire for more information about 5-Amino-2-(phenylmethoxy)benzoic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>ML604440 is a potent inhibitor of cyclin-dependent kinases (CDKs) and has shown anti-cancer activity in various human cancer cell lines. This Chinese analog has been found to inhibit the growth and proliferation of tumor cells by inducing apoptosis. ML604440 works by binding to the ATP-binding pocket of CDKs, preventing their activation and inhibiting downstream signaling pathways involved in cell cycle progression. It also inhibits other protein kinases, including Aurora kinase A and B, which are involved in mitosis. ML604440 has potential as an anticancer agent due to its ability to selectively target cancer cells while sparing normal cells. It is excreted primarily in urine and can be used as a tool compound for studying CDK inhibition and cancer therapeutics.</p>

<p>Deacetyl-N,o-didemethyldiltiazem is a drug product that is used for the treatment of hypertension. It is a synthetic compound and has not been found in nature. The impurity standard for this product is an analytical chemical that can be used to identify the presence of impurities in a sample. Deacetyl-N,o-didemethyldiltiazem can be synthesized from commercially available starting materials using custom synthesis methods. It is an API impurity and can be developed into a drug by researching and developing it as a niche therapy for hypertension. This compound has high purity and can be used as an HPLC standard.</p>

Pindolol EP Impurity F is a metabolite of the drug pindolol. It is an impurity found in the product or in the analytical sample. Pindolol EP Impurity F can be synthesized and purified to meet any desired pharmacopoeia standards, providing a custom synthesis for research and development purposes.

Lactose conjugate degradation product of pregabalin

<p>3-(Aminomethylene)-6-phenyl-2,5-piperazinedione is a potent anticancer agent that has shown promising results in inhibiting cancer cell growth. This compound is an analog of etomidate, a drug used for anesthesia induction. It has been found to induce apoptosis in human tumor cells and inhibit the activity of kinases, which are enzymes involved in cancer progression. The compound has also been detected in human urine, indicating its potential for use as a biomarker for cancer diagnosis and treatment monitoring. Additionally, 3-(Aminomethylene)-6-phenyl-2,5-piperazinedione has shown inhibitory effects on elastase activity, which may contribute to its potential as a therapeutic agent against cancer.</p>

Finasteride 2-(2-methylpropanol)amide β-D-glucuronide is an inhibitor that has been shown to induce apoptosis in cancer cells. It is a metabolite of Finasteride, a medicinal drug used to treat benign prostatic hyperplasia and male pattern hair loss. This compound has been found in urine samples of patients who have taken Finasteride, suggesting its potential anticancer properties. Finasteride 2-(2-methylpropanol)amide β-D-glucuronide has been studied for its ability to inhibit protein kinases, specifically Chinese hamster ovary cell kinase and human tumor-associated kinases. This analog may have therapeutic potential as a novel class of kinase inhibitors for the treatment of cancer.