APIs pour la recherche et les impuretés

<p>Tetrahydrofuran-3-yl 4-methylbenzenesulfonate is a synthetic compound that has been used as an impurity standard for the drug product and as a metabolite in pharmacopoeia. Tetrahydrofuran-3-yl 4-methylbenzenesulfonate is also used in research and development, including drug metabolism studies. Tetrahydrofuran-3-yl 4-methylbenzenesulfonate is a high purity and custom synthesis that is used as an analytical standard for HPLC.</p>

<p>3,4-Bis(2-methoxyethoxy)benzoic acid ethyl ester is a compound that has been shown to have bactericidal activity against Gram-positive bacteria. It is currently being evaluated for use in the preparation of samples for microbiological analysis and as an antimicrobial agent. 3,4-Bis(2-methoxyethoxy)benzoic acid ethyl ester has been shown to inhibit the growth of tumor cells in vitro and may be useful in the treatment of cancers. This compound also inhibits the production of nitric oxide by nitro groups and hydrogen bonds with amino acids on proteins or carbohydrates that are required for bacterial cell wall biosynthesis.</p>

<p>Amoxicillin EP Impurity K is a synthetic impurity found in amoxicillin. Amoxicillin is an antibiotic that inhibits the growth of bacteria by binding to the 50S ribosomal subunit. Amoxicillin EP Impurity K is a metabolite of amoxicillin, which has been shown to inhibit protein synthesis and cell division. This impurity can be used as a reference material for analytical purposes or as a standard in drug development.</p>

<p>(2S,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol is a synthetic drug product that has been found as an impurity in other drugs. It has a natural origin and can be synthesized by chemical methods. This compound is used in chemical analysis to determine the purity of the drug product. This compound is also used in research and development to develop drugs for niche markets. (2S,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol has high purity and meets pharmacopoeia standards.</p>

Furegrelate is an analytical reference standard for the hydroxylation of 4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl[(5S)-tetrahydro-5-methyl-2-furanyl]-methanone. Furegrelate is a synthetic drug product that has been used in pharmacological and toxicological research. It is a metabolite of the drug Furosemide, which is used to treat heart failure and high blood pressure. Furegrelate has also been found as an impurity in the API (active pharmaceutical ingredient) of other drugs such as Carvedilol and Metoprolol.

Sb 205607 dihydrobromide is a chemotherapeutic agent that has been shown to inhibit the growth of cancer cells in vitro. It is a small molecule that contains bromine atoms, which are able to react with DNA and cause cross-linking. Sb 205607 dihydrobromide has also been shown to be an agonist at glutathione S-transferase receptors and attenuate the activation of NF-κB. This drug may be used as a chemotherapeutic agent in the treatment of cancer.

<p>Imiloxan hydrochloride is a diagnostic agent that is used to diagnose Parkinson's disease and other neurological disorders. Imiloxan hydrochloride has been shown to increase dopamine levels in the brain and improve symptoms of Parkinson's disease. Imiloxan hydrochloride inhibits the glucuronidation of dopamine, which leads to an increase in neurotransmitter levels. This drug also has a pain-relieving effect by increasing norepinephrine levels and blocking the reuptake of serotonin. Imiloxan hydrochloride is a prodrug that is metabolized into methyl-d-aspartate and norepinephrine through conjugation with fatty acids and esters.</p>

4-(4-Chlorophenyl)-4-hydroxypiperidine is a chemical compound that has been shown to inhibit the human liver enzyme, cytochrome P450. It can be used as a probe for determining the presence of this enzyme in a variety of samples, including urine and serum. 4-(4-Chlorophenyl)-4-hydroxypiperidine is also a substrate for recombinant cytochrome P450 enzymes and can be used to study their properties. This compound has been shown to produce dopamine in the brain, which may contribute to its effects on locomotor activity. The stability of 4-(4-chlorophenyl)-4-hydroxypiperidine was found to be dependent on chemical species and it was found that cancer cells were more sensitive than noncancerous prostate cells.

4-(5-Chloro-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)-1-formylpiperidine is a drug product that is used for the synthesis of pharmaceuticals. It is an analytical standard for HPLC and an impurity in the production of other drugs. 4-(5-Chloro-2-oxo-2,3-dihydro-1H-benzimidazol-1H)-1 formylpiperidine has been shown to have natural and synthetic origins, as well as being produced by custom synthesis. The compound has been shown to be effective in drug development and research and development for a niche market. This product is intended for use as an analytical standard in pharmacopoeia or HPLC analyses or as a synthetic intermediate in the manufacture of other drugs.

2-Hydroxymethyl-3-(phenylsulfonyl)propanamide (HMPPA) is a metabolite of n-(2,4-dichlorophenyl)-2-hydroxy-2-methylpropanamide (DCPAMP), an impurity of the drug product. HMPPA can be synthesized and used as a research and development standard for DCPAMP with a purity of 99%. It is also used as a standard in pharmacopoeia and to develop drugs.

<p>Thiamine triphosphate is a coenzyme that plays an essential role in many biochemical reactions. It is a cofactor for pyruvate dehydrogenase, alpha-ketoglutarate dehydrogenase, and transketolase. Thiamine triphosphate is required for the production of acetyl-CoA from carbohydrates and amino acids. This coenzyme also participates in the synthesis of thiamin, which is necessary for maintaining normal nerve function. The x-ray crystal structures of thiamine triphosphate with its substrate molecule have been determined by X-ray crystallography. These structures are available at PDB ID 1TMP and 1THP. The reaction solution used to determine these structures was phosphate buffer, pH 7.0, at 30 degrees Celsius. The receptor activity of this enzyme has been studied using rat brain homogenates following incubation with various concentrations of prasugrel (a substrate molecule). Enzyme</p>

BAMEA-O16B is a human analog with potent anticancer properties. This Chinese medicinal compound has been shown to induce apoptosis in tumor cells and inhibit the growth of cancer cells. BAMEA-O16B acts as an inhibitor of protein kinases, which play a key role in cell cycle regulation and are often overexpressed in cancer cells. This compound has been found to be effective against a range of cancers, including breast, lung, and colon cancer. In addition, BAMEA-O16B has been shown to have low toxicity and is excreted primarily in urine. This makes it a promising candidate for further development as an anticancer therapy.

PBDE 194 is an analog of a kinase inhibitor that has shown potential as an anticancer agent. It has been found to inhibit the activity of kinases, which are enzymes involved in cell signaling pathways that can contribute to cancer growth and proliferation. PBDE 194 has been shown to induce apoptosis, or programmed cell death, in cancer cells. Additionally, it has been found to inhibit the growth of tumor cells in human and Chinese hamster models. This compound may be a promising candidate for the development of novel anticancer drugs. Urine samples have been used to detect protein inhibitors of PBDE 194, which could aid in the identification of patients who may benefit from this treatment.

<p>FR183998 is an anticancer drug that is derived from Chinese urine. It is a potent inhibitor of human tumor cell growth and has been shown to induce apoptosis in cancer cells. FR183998 works by inhibiting kinases, which are proteins that play a critical role in cell division and proliferation. This drug has been found to be effective against a wide range of cancers, including breast, lung, and colon cancer. Additionally, FR183998 has analogs that have been developed as kinase inhibitors for the treatment of various types of cancer. The use of FR183998 as an anticancer agent shows great promise in the development of new treatments for cancer patients.</p>

<p>Torasemide Impurity E is a drug product that belongs to the group of impurities. It is a natural product and can be found in the environment. Torasemide Impurity E has been shown to inhibit bacterial growth in vitro and also antimicrobial activity against gram-positive bacteria, such as Staphylococcus aureus. Torasemide Impurity E has been shown to have no cytotoxic effects on human erythrocytes.</p>

Quinovin is a Chinese medicinal compound that has been shown to have potent anticancer properties. It works by inhibiting kinases, which are enzymes that play a crucial role in the growth and proliferation of cancer cells. Quinovin has been found to induce apoptosis, or programmed cell death, in various types of cancer cells. This compound is an analog of other kinase inhibitors that have been developed for the treatment of cancer in humans. Quinovin has also been found to inhibit the growth of tumors in animal models and to be excreted in urine after administration. Overall, Quinovin represents a promising candidate for the development of new anticancer therapies.

<p>Impurity F is a metabolite of Fexofenadine. It is an impurity that can be found in the drug product and is used as a research and development standard for impurities. Impurity F has been shown to be a metabolite of Fexofenadine in human liver microsomes, and this metabolite has also been shown to have antihistamine properties. This impurity is used as a pharmacopoeia reference standard for HPLC analysis of fluoroquinolones, but it does not have any therapeutic value.</p>

<p>Pf9 tetrasodium is a high purity, HPLC standard. It is used as an analytical standard in metabolism studies and as a synthetic impurity standard. Pf9 tetrasodium is also used in drug development research and development to create new drugs and to optimize the production of existing drugs. This product is sold in quantities of 100 grams or more. Pf9 tetrasodium has CAS number 851265-78-6.</p>

<p>Vinorelbine N-methiodide is a drug product that is used for the treatment of various types of cancer. It is an active form of vinorelbine, which is an anti-cancer drug that belongs to the class of vinca alkaloids. Vinorelbine N-methiodide can be found as a natural product or can be synthesized in the laboratory. It has been shown to inhibit DNA synthesis, protein synthesis, and cell division with high specificity. This drug is administered intravenously and can cause nausea, vomiting, diarrhea, anemia, bone marrow suppression, and liver damage. The most common side effects are anemia and constipation.</p>

<p>Fosfomycin trometamol EP impurity A disodium is a research and development impurity standard. It is a custom synthesis that is used as a drug product, synthetic, high purity, pharmacopoeia, drug development, metabolite, niche, analytical and natural. Fosfomycin trometamol EP impurity A disodium has been shown to have an HPLC standard and CAS No. 84954-80-3(free base).</p>

Ivacaftor is a drug product that is used for the treatment of cystic fibrosis. It is an active ingredient of Kalydeco, which is a combination therapy to treat cystic fibrosis. Ivacaftor is the first FDA-approved drug for the treatment of CF in patients with specific mutations. The metabolism of ivacaftor has been studied by analytical methods and it has been shown to have natural impurities. The API impurity and synthetic impurity standards are available for custom synthesis and can be ordered from a specialty manufacturer. Ivacaftor requires high purity and pharmacopoeia-grade standards for research and development as well as niche markets, such as HPLC standard or high purity.

<p>4'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxylic acid (4BMBCA) is a chemical compound that is used as an analytical method in drug discovery and development. It has been shown to have contraceptive properties, which may be due to its ability to inhibit the synthesis of progesterone. 4BMBCA has also been shown to reduce the development of primary tumors in mice. The drug is also able to cause stomatitis and show antimicrobial resistance in humans. Symptoms of this drug include fever, nausea, vomiting, diarrhea, headache, and stomatitis. 4BMBCA has been found by plasma mass spectrometry to be effective against several bacteria types including Staphylococcus aureus and Escherichia coli.</p>

(R)-Imazamox is a medicinal compound that acts as a potent protein kinase inhibitor. It has been shown to be effective in the treatment of various types of cancer, including leukemia, by inducing apoptosis and inhibiting tumor cell growth. (R)-Imazamox specifically targets the cell cycle of cancer cells, preventing them from dividing and multiplying. It has also been found to have anti-inflammatory properties and is being studied for its potential use in treating inflammatory diseases such as arthritis. Chinese herbal medicine has long recognized the benefits of (R)-Imazamox, using it in traditional remedies to treat urinary issues and other ailments. Overall, (R)-Imazamox is a highly effective anticancer agent with promising potential for future medical applications.

<p>Chlorthalidone impurity A is an impurity in Chlorthalidone. It was found to be a flow rate marker with an analytical method that has been implemented and calibrated. The calibration curve is linear and the particle size of this compound is between 2-4 microns. This compound can be detected by using a particle size analyzer (PSA) or rp-hplc. In order to analyze this compound, the calibration must be done with ammonium acetate as the mobile phase and acetonitrile as the stationary phase. The wavelength for detection is 220 nm and the runtime is 1 minute. Analytical methods such as chromatographic methods, ultraviolet spectroscopy, nuclear magnetic resonance spectroscopy, and mass spectroscopy may also be used to identify this compound.</p>

<p>Taiwanin C is an analog of dabigatran, a potent inhibitor of kinases that has been shown to have anticancer properties. It has been found to inhibit the growth of tumor cells in vitro and in vivo, inducing apoptosis and reducing protein expression. Taiwanin C has also shown promising results in inhibiting the activity of various kinases involved in cancer cell proliferation and survival. This compound is derived from Chinese herbal medicine and can be detected in urine after administration. Its potential as an anticancer agent makes it a promising area for further research into new cancer therapies.</p>

<p>Flumethasone Impurity 11 is a drug product that is used in the research and development of drugs. Flumethasone Impurity 11 is an analytical impurity that can be found in the natural API, Flumethasone. It has a molecular weight of 537.3 and its CAS number is 1069-81-4. Flumethasone Impurity 11 is synthesized from other synthetic chemicals and is used as an impurity standard for HPLC analysis. This product has been shown to be pharmacopoeia grade with a purity of 99%.</p>

<p>L-741,742 Hydrochloride is an atypical antipsychotic drug that has been shown to inhibit the growth of malignant brain tumors in animal models. L-741,742 Hydrochloride has also been shown to be effective in treating schizophrenic patients who have not responded to typical antipsychotics and for whom the side effects are intolerable. It is a dopamine D4 receptor antagonist that inhibits the binding of dopamine to this receptor, thereby blocking its stimulatory effect on cells. This drug also has an inhibitory effect on the dopamine D4 receptor, which can reduce psychotic symptoms in schizophrenic patients. L-741,742 Hydrochloride binds with high affinity to CB1 and CB2 receptors in cell cultures and has shown anticancer efficacy in cancer cells.</p>

<p>N,N'-Dimethyl-2-nitro-1,1-ethendiamine is a protonated form of N,N'-dimethyl-2-nitroetheneamine. It has been shown to be an equilibrating agent for the equilibrium between the protonated and unprotonated forms of N,N'-dimethyl-2-nitroetheneamine in alkaline solution. In this way it can be used to determine the pH of an unknown solution. The equilibrium constant is 10^14 at 25 degrees Celsius. This constant varies with temperature and concentration of N,N'-dimethyl-2-nitroetheneamine. The electronic spectra show that this molecule is an anion.</p>

<p>Enantiomer of Perindopril t-Butylamine</p>

<p>Indenestrol-d3 is a synthetic, natural or semi-synthetic metabolite of indenestrol. It is an impurity in the drug product and is detectable by HPLC. Indenestrol-d3 has been shown to be metabolized by cytochrome P450 into 17β-hydroxyindenestrol, which is not active. This impurity can be used as a reference standard for HPLC analysis of indenestrol in pharmaceutical products.</p>

Please enquire for more information about 3-Desmethyl-3-(5-oxohexyl) pentoxifylline including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Salmeterol ep impurity A is an API impurity in the drug product 1-(RS)-1-[4-hydroxy-3-(hydroxymethylphenyl]-2-[(4-phenylbutyl)aminoethanol. It is a synthetic, natural, and pharmacopoeia impurity standard. The CAS number for this compound is 1798014-51-3. Salmeterol ep impurity A has a molecular weight of 255.9 g/mol and chemical formula of C24H30ClNO5.</p>

Rotogotine EP Impurity J is a synthetic drug that is metabolized to produce the active form, rotogotine. Rotogotine is used in the treatment of Parkinson's disease and restless leg syndrome. This impurity standard may be used as a reference for analytical methods such as HPLC or GC.

<p>N-Nitroso N-hydroxy cyclohexanamine is an analog of betamethasone and a potent inhibitor of kinases. It has been shown to have anticancer properties by inducing apoptosis in cancer cells. This compound is excreted in urine and has been studied extensively in Chinese populations for its potential as an anticancer agent. N-Nitroso N-hydroxy cyclohexanamine inhibits the activity of kinases, which are important enzymes involved in cell signaling pathways that regulate cell growth and division. This inhibition leads to the suppression of tumor growth and the induction of apoptosis in cancer cells. Additionally, this compound has been found to be a potent inhibitor of vitamin D receptor (VDR) and may play a role in regulating VDR-mediated gene expression.</p>

<p>((E)-5-((M-[(2-Carboxyethyl)carbamoyl]phenyl)azo)-2-salicylic acid) is a drug product. It is a synthetic, white to off-white powder that has a molecular weight of 246.9 g/mol and an assay of 99%. The impurity standard for this product is (E)-5-(4-(methylsulfonyl)phenylazo)-2-salicylic acid.</p>

<p>2-Oxo clopidogrel hydrochloride is a drug product that belongs to the class of drugs called platelet aggregation inhibitors. It is a prodrug that is metabolized in vivo to form the active metabolite, 2-oxo-clopidogrel acid. This compound inhibits ADP and collagen-induced platelet aggregation by blocking the binding of adenosine diphosphate (ADP) to its receptor on the surface of platelets. The drug has been shown to have antiplatelet activity and inhibit thrombus formation in humans, as well as in animal models of atherosclerosis and coronary artery disease.</p>

<p>Lamivudine is an antiviral drug that belongs to the group of nucleoside analogues. It is a prodrug that is activated by intracellular phosphorylation to form the active compound, lamivudine triphosphate (L-TTP). L-TTP inhibits viral replication by competing with natural substrates for incorporation into viral DNA. The antiviral activity of L-TTP has been shown in animals and humans with hepatitis B virus or human immunodeficiency virus type 1 (HIV-1) infections. Lamivudine S-oxide is a stereoselective form of lamivudine, which can be used for chemoprophylaxis against the pandemic H1N1 virus. This drug has shown to have a lower toxicity profile than other drugs used for this purpose.</p>

S-(9H-Fluoren-9-ylmethyl)-N-[(2-propen-1-yloxy)carbonyl]-L-cysteine is a drug product that is used as an analytical standard for HPLC. It can be used as a metabolite, impurity standard, or API impurity. This product is also used for research and development in the field of drug development. The purity of this compound is high and it has been shown to have niche applications in pharmacopoeia studies.

<p>2-Hydroxy-5-[2-[4-(2-imino-1(2H)-pyridinyl)phenyl]diazenyl]-benzoic acid (DPC) is a drug product that is used in pharmaceutical research and development. It is an impurity standard for HPLC analysis. DPC has been shown to be a metabolite of the drug product 2,6-dimethoxy-N-(3-methylphenyl)pyrimidine-4,6-diamine (DMX), which is used in the treatment of cancer. Impurities standards are important for ensuring the quality of drugs and ensuring that they are safe for human use. This product can also be synthesized from commercially available amino acids.</p>

Doxazosin-d8 hydrochloride is an analytical reference standard for HPLC and LCMS, and a drug development impurity. It is a metabolite of doxazosin that is used as an impurity in the manufacture of doxazosin. Doxazosin-d8 hydrochloride has been shown to be a substrate for CYP3A4, where it undergoes oxidation to form 2-(2-hydroxyphenyl)-N-[(1S)-1-[[(2R)-2-methylpropyl]sulfonyl]-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl]-N-(2,6 dimethylphenyl)acetamide (CYP3A4). This metabolite may contribute to the pharmacological activity of doxazosin.

(5E)-2,2-Dimethyl-7-[methyl(1-naphthalenylmethyl)amino]-5-hepten-3-ynoic acid is a drug product that has been custom synthesized. It is available in high purity (>98%) and with analytical data. This chemical is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. (5E)-2,2-Dimethyl-7-[methyl(1-naphthalenylmethyl)amino]-5-hepten-3-ynoic acid has been shown to have pharmacological activity on the central nervous system and may be used as an antidepressant drug candidate.

N-Demethyl pazopanib is a synthetic drug that has been researched and developed for the treatment of cancer. It is an impurity standard, custom synthesis, and drug product. Synthetic N-demethyl pazopanib is used in clinical trials as a research and development tool to explore the metabolism of this drug and its metabolites. High purity N-demethyl pazopanib is used as a pharmacopoeia reference material for HPLC analysis in pharmacological studies. The metabolite of N-demethyl pazopanib has been found to be carcinogenic in animal studies. Metabolism studies have shown that N-demethyl pazopanib undergoes extensive hydroxylation and glucuronidation, which are detoxification pathways for xenobiotics in mammals.

<p>N-(3-Trifluoromethylphenyl)-phenylamine is a research and development drug product that is used as an analytical impurity standard. It has a CAS number of 101-23-5 and is classified under the trade name 3TFPPA. The chemical formula for N-(3-Trifluoromethylphenyl)-phenylamine is C12H8F3NO. This compound can be synthesized from phenylamine, 3-trifluoromethylaniline, and hydrochloric acid. The molecular weight of this compound is 197.19 g/mol, which falls within the range of 195 to 200 g/mol. N-(3-Trifluoromethylphenyl)-phenylamine can be found in the following pharmacopoeia: USP (United States Pharmacopeia), EP (European Pharmacopoeia), JP (Japanese Pharmacopeia), BP</p>

Methyl 4-methyl-3-[2-(propylamino)acetamido]thiophene-2-carboxylate is an impurity that can be found in the drug product. It is a metabolite of clozapine, which is used to treat schizophrenia and other psychiatric disorders. This impurity can be detected by HPLC or LC/MS analysis and quantified using a calibration curve generated from standards. Methyl 4-methyl-3-[2-(propylamino)acetamido]thiophene-2-carboxylate may also be found in the urine as an indicator of clozapine use.

<p>(4R)-1-(4-O-b-D-Galactopyranosyl-b-D-glucopyranosyl)-4-(2-methylpropyl)-2-pyrrolidinone is a synthetic, impurity standard and research and development compound. (4R)-1-(4-O-b-D-Galactopyranosyl-b-D-glucopyranosyl)-4-(2-methylpropyl)-2pyrrolidinone is used as an analytical reference in the synthesis of other compounds. It is also used in drug development for the treatment of tuberculosis. This product has a high purity level and is pharmacopoeia grade.</p>

<p>Fexofenadine Impurity G is an impurity that is found in the drug Fexofenadine. This impurity can be identified and quantified using HPLC with a UV detector at 254 nm. Fexofenadine Impurity G has been classified as a natural metabolite of Fexofenadine. It is also considered to be a synthetic impurity because it can be synthesized in the laboratory.</p>

<p>2-Hydroxy-5-[2-[4-[[(6-methyl-2-pyridinyl)amino]sulfonyl]phenyl]diazenyl]benzoic acid is a synthetic drug product that has not been approved for clinical use. 2-Hydroxy-5-[2-[4-[[(6-methyl-2-pyridinyl)amino]sulfonyl]phenyl]- diazenyl]benzoic acid is a metabolite of the drug product, 3-(2,4,6,-trimethoxybenzoyl)-1-(pyridinium methyl) piperidine. This metabolite was isolated and characterized using high performance liquid chromatography (HPLC), gas chromatography (GC), and nuclear magnetic resonance spectroscopy.</p>

Act 373898 disodium (A37) is a custom synthesis drug product that is used as an analytical standard for the metabolism of actiomycin D. A37 is metabolized to form the natural metabolite, Act 373898 monosodium (A36). This drug product is also used in drug development and has been shown to be pharmacologically active. A37 has been shown in vitro to inhibit protein synthesis by binding to ribosomes and inhibiting peptidyl transferase activity. A37 is not a natural compound but it does possess niche properties. It has been shown to be synthesized from acetamide, acetic acid, and sodium hydroxide. The chemical structure of A37 may contain impurities such as sodium acetate and hydrochloric acid.

Diethyl 2-propylimidazole-4,5-dicarboxylate is a synthesized intermediate that can be used in the synthesis of other organic compounds. It is a diethyl ester of tartaric acid and an intermediate in the preparation of other organic compounds. The diethyl ester is made by nitrating diethyl to give diethyl nitrite, which is then reacted with tartaric acid to form the desired product. Diethyl 2-propylimidazole-4,5-dicarboxylate has been shown to be toxic, but it has not been shown to have any carcinogenic effects.

Monophenyl succinate is an organic compound that is a derivative of succinic acid. It contains a hydroxyl group, which reacts with hydrogen chloride to form a cross-linking agent. The diameters of the particles are between 1 and 100 nm. Monophenyl succinate can be used as a cross-linking agent in polymers and coatings, as well as an antihypertensive drug. The hydroxy group on the monophenyl group has ester linkages with the methyl and ethoxycarbonyl groups on the phenyl group. This compound also has methoxy groups and chlorine atoms attached to it. The reaction products of this compound are hydrogen chloride, hydroxyl group, and diameter.

Edoxaban 4-carboxylic acid hydrochloride is a drug product with high purity. It has been synthesized using natural ingredients and is an analytical standard. The metabolite of edoxaban 4-carboxylic acid hydrochloride is the substance CAS No. 834919-19-6, which is also a metabolite for other drugs. Edoxaban 4-carboxylic acid hydrochloride can be used in drug development and pharmacopoeia research, as well as in niche areas such as HPLC standards and analytical research.

<p>9-Hydroxymethyl-10-carbamoylacridan is an active metabolite of carbamazepine. It is a potent competitive inhibitor of the enzyme acetylcholinesterase, which leads to increased levels of acetylcholine in the human brain and causes decreased seizure threshold. 9-Hydroxymethyl-10-carbamoylacridan can be found in wastewater and it has been detected in the water supply and in human serum. 9-Hydroxymethyl-10-carbamoylacridan is also present in human urine and can be detected by high performance liquid chromatography (HPLC). This compound has been shown to cause epileptic seizures in humans.</p>

Please enquire for more information about 7-Hydroxy-furo[3,4-b]pyrazin-5-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Please enquire for more information about N-Acetyl o-benzyl 5’-epi lamivudine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3-Chloro-10-[3-(dimethylamino)propyl]-9(10H)-acridinone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

3,5-Dimethyl-2-(ethoxycarbonyl)-4-pyrone is a drug product that has been used as an HPLC standard. It has been used in the development of new drugs, and is a metabolite of many drugs including amoxicillin. 3,5-Dimethyl-2-(ethoxycarbonyl)-4-pyrone is also an impurity in some pharmaceuticals, such as the antibiotic cefazolin. This compound was synthesized for use as a research and development chemical. The synthesis of 3,5-dimethyl-2-(ethoxycarbonyl)-4-pyrone is based on the reaction between 2-chloroacetophenone and ethyl formate with potassium hydroxide. 3,5-dimethyl-2-(ethoxycarbonyl)-4-pyrone is an analytical standard for impurities in API compounds.

Ropivacaine N-Oxide is a synthetic drug used to relieve pain during surgery. It is metabolized by the liver, with metabolites excreted in the urine. Ropivacaine N-Oxide is used as an impurity standard and a research and development compound for custom synthesis. The chemical name of this product is 1-(3-Chlorophenyl)-N-[1-(2,6-dichloro-4-nitrophenyl)ethyl]propane-1,3 dione.

Tetrabromobisphenol A dimethyl ether is a high yield, biotransformed product that is synthesized from brominated phenols. It has been shown to be radiation-resistant and can be used as an extender for polymers in the hydroponic industry. Tetrabromobisphenol A dimethyl ether can also be used as a matrix metalloproteinase inhibitor, which is thought to inhibit the degradation of collagen during wound healing. This product has also been shown to have enzymatic activity in human serum.

<p>Flubendazole alcohol is a drug product that is an impurity standard for the synthesis of flubendazole. It is also used as a metabolite and an analytical reference material in drug development, natural product research and development, and metabolism studies. Flubendazole alcohol is considered to be high purity, with 98% purity by HPLC standards. The CAS number for this product is 82050-12-2.</p>

<p>2,4-Dicyano-3-isobutyl-glutaric acid is an impurity found in the synthesis of the drug product 2,4-D. It is a white solid that has been shown to have analytical properties. This compound has been used as a research and development standard and is used as an analytical reagent in HPLC. 2,4-Dicyano-3-isobutyl-glutaric acid can be custom synthesized or obtained from natural sources. Metabolites of 2,4-dicyano-3-isobutyl glutaric acid are not known at this time.</p>

<p>L-745,870 is a subchronic atypical antipsychotic agent that is a potent D4 receptor agonist. Its efficacy in treating various mental disorders has been demonstrated in clinical studies with animals. L-745,870 has shown antidyskinetic activity in animal models of Parkinson's disease and dyskinesia. The molecular target for this drug is the dopamine D4 receptor. Clinical development of L-745,870 has begun in human studies.</p>

Please enquire for more information about Di-destriazole desmethyl anastrozole dimer impurity including the price, delivery time and more detailed product information at the technical inquiry form on this page

2,3-Dimethyl-N-phenylbenzenamine is a medicinal compound that has been found in urine and has shown potential as an anticancer agent. It acts as a kinase inhibitor, specifically targeting proteins involved in cancer cell growth and survival. In Chinese hamster ovary cells, this compound has been shown to inhibit the activity of protein kinases and induce apoptosis, or programmed cell death. This analog also displays potent antitumor activity against leukemia cells in vitro. As a promising candidate for cancer treatment, 2,3-Dimethyl-N-phenylbenzenamine may serve as a valuable tool in developing novel inhibitors for various types of cancers.

Kaempferol di-O-methoxymethyl ether is a natural product that has been identified as a metabolite of kaempferol. It is an API impurity in the drug product and can also be found in the synthesis of kaempferol. Kaempferol di-O-methoxymethyl ether is a synthetic compound that can be used for drug development, research and development, and analytical purposes. It is an HPLC standard for pharmacopoeia.

Lamivudine is an antiviral drug that belongs to the group of nucleoside analogues. It can be used as a single agent or in combination with other antiviral drugs for the treatment of HIV infection. Lamivudine is a prodrug that is converted to its active form, which inhibits viral DNA synthesis by competing with natural substrates for incorporation into viral DNA by inhibiting viral polymerase activity and causing chain termination. The long-term toxicity of lamivudine has been studied in animals and humans. Although it does not cause any serious side effects, it can cause hepatitis and reactivation of hepatitis B virus (HBV). Lamivudine has been shown to inhibit the IL-2 receptor on T cells, which may contribute to its beneficial effect on HBV.

<p>(2S,2S,Trans)-saxagliptin is a drug product that has been developed as an oral anti-diabetic agent. It is a synthetic compound with the chemical name of (2S,2S,Trans)-4-[(1R)-1-[[(3Z)-3-(dimethylamino)-1-[(4-methylphenyl)sulfonyl]propanoyl]amino]-2-methylpropyl]-N-[4-(6-methoxy-3-pyridinyl)benzoyl]glycine. The synthesis of this drug is based on the natural amino acid sequence of the human insulin molecule. (2S,2S,Trans)-saxagliptin has been shown to be metabolized in vivo through hydroxylation and glucuronidation pathways and to have a half life of approximately 10 hours in humans. This drug product is intended for research and development purposes only</p>

Please enquire for more information about 2-(4-Nitro-1-oxoisoindolin-2-yl)pentanedioic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

(R)-1-Trichloromethyl-1,2,3,4-tetrahydro-β-carboline is a potent inhibitor of kinases that play key roles in cancer. It is an analog of a natural product found in human urine and has been shown to have anticancer activity in tumor models. This compound works by inhibiting the activity of protein kinases involved in cell proliferation and survival, leading to apoptosis or programmed cell death. (R)-1-Trichloromethyl-1,2,3,4-tetrahydro-β-carboline has potential as a medicinal agent for the treatment of cancer due to its ability to inhibit cancer cell growth and promote apoptosis. Its unique structure makes it a promising candidate for further development as a kinase inhibitor.

<p>6-Chloro-5-nitro-2-(propylthio)-4(1H)-pyrimidinone is a compound that is commonly used as an intermediate in the synthesis of various chemicals. It is known for its impurities, including methanol, sulfadiazine, and hydrochloric acid. This compound has been studied for its potential therapeutic applications, including its ability to activate interferon and promote hematopoiesis. Additionally, it has been found to exhibit antioxidant activity and can help prevent lipid peroxidation. 6-Chloro-5-nitro-2-(propylthio)-4(1H)-pyrimidinone also shows promise as a photodegradation agent for certain herbicides and prasugrel. Its reactive nature makes it suitable for various chemical reactions and applications in research and development.</p>

2-(Sulfoacetamido) dimoxystrobin acetic acid disodium is a drug product that is an impurity of the API 2,5-dimethoxy-4-hydroxyphenylacetic acid. The CAS number for this impurity is 1196157-87-5. It is an analytical standard that is used in Metabolism studies and Natural products research. This compound is a Synthetic and Custom synthesis. It has been shown to be effective against drug development and research and development, as well as niche markets. This compound also has pharmacopoeia standards, which are high purity levels.

<p>2-Amino-5,6-dichloro-3-(4H)-quinazoline acetic acid benzyl ester hydrobromide is a drug product that is used as an analytical reference standard for the identification of impurities in aminoglycosides. 2-Amino-5,6-dichloro-3-(4H)-quinazoline acetic acid benzyl ester hydrobromide is a synthetic compound that has been shown to be metabolized in vivo to 3-(2,4-dichlorophenoxy)propionic acid and 3-(2,4-dichlorophenoxy)acrylic acid. This product has been shown to have niche applications such as metabolism studies.</p>

Rhubofix is a medicinal product that contains xylose, a natural sugar found in human urine and protein. It has been shown to be an inhibitor of tumor kinases, which are enzymes involved in the growth and proliferation of cancer cells. Rhubofix has been found to induce apoptosis, or programmed cell death, in cancer cells, making it a potential treatment for various types of cancer. This product also acts as an inhibitor of the cell cycle, preventing cancer cells from dividing and multiplying. Rhubofix has been used traditionally in Chinese medicine as an inhibitor of kinase activity and has shown promising results in preclinical studies as a potential anti-cancer agent.

<p>N-Debenzoyl-N-hexanoylpaclitaxel (DHBPTx) is an analog of paclitaxel. It inhibits cell proliferation by binding to the diketone group at the C-10 position of baccatin III, which inhibits the synthesis of taxol and other natural products with a diketone group at this position. DHBPTx is effective against colorectal carcinoma cells in culture, but has not been tested in vivo. This drug has also been shown to be effective against breast cancer cells that express high levels of 10-deacetylase activity. It is metabolized into 10-deacetylbaccatin III, which binds to cellular protein kinase C and causes inhibition of mitosis and apoptosis. In addition, DHBPTx can be conjugated with other drugs such as doxorubicin or vincristine to increase their effectiveness.</p>

<p>5-Chloro-1,3-dihydro-1-methyl-3-phenyl-2H-benzimidazol-2-one is a synthetic impurity that may be found in drug products. It is used as an analytical standard and is metabolized to 5,5'-dichloroquinoline by hydrolysis of the acetal linkage. The metabolite 5,5'-dichloroquinoline has been shown to have antiplatelet effects in vitro and may contribute to the antithrombotic activity of the parent compound. This substance is not intended for clinical use.</p>

<p>N-Methyl amisulpride is a synthetic drug with antipsychotic properties. It is used in the treatment of schizophrenia and related psychotic disorders. N-Methyl amisulpride has been shown to be effective against the metabolites, such as naphthol and homovanillic acid, that are produced by dopamine and serotonin. This product can also be used as an impurity standard for the synthesis of other drugs or for HPLC analysis.</p>

Please enquire for more information about 7-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Amlodipine besilate impurity B is a metabolite of amlodipine besilate. It is an impurity that originates from the synthesis of amlodipine besilate, which is a calcium channel blocker used to treat high blood pressure. Amlodipine besilate impurity B can be synthesized or found in nature, depending on the desired purity and availability.</p>

<p>Peraquinsin is a potent anticancer drug that targets human protein kinases, which are enzymes involved in cell cycle regulation and apoptosis. It is an analog of a natural product found in urine, and has been shown to inhibit the activity of several kinases that are important for tumor growth. Peraquinsin is a promising inhibitor of cancer cell proliferation, with potential applications in medicinal chemistry. Its mechanism of action involves inhibiting the activity of specific protein kinases, leading to cell cycle arrest and apoptosis. This drug has shown great potential as an anticancer agent due to its ability to target multiple signaling pathways involved in cancer development and progression.</p>

Please enquire for more information about 2-(3,4-Diethoxyphenyl)-3-hydroxy-4H-1-benzopyran-4-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Carbocisteine is a drug that belongs to the class of non-steroidal anti-inflammatory drugs. It is used in the treatment of bronchial asthma, bronchitis, and chronic obstructive pulmonary disease. Carbocisteine has been shown to inhibit platelet aggregation and to reduce blood viscosity. Carbocisteine may also be classified as a drug that binds to octadecyl groups. In this way it can be used as an analytical reagent for substances with similar chemical structures.</p>

Roflumilast Impurity E is a reagent that is used to monitor the pharmacokinetic properties of roflumilast. Roflumilast Impurity E is an acidic component of roflumilast that may be synthesized from acetone and acid hydrolysis. It has been shown to be hepatotoxic, but it does not have any adverse effects on the liver when taken with other drugs such as erythromycin and phenytoin. This substance also has a spectrum of action that includes pulmonary disease, which makes it useful for treating bronchitis and asthma.

<p>5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]-methylene]-2,4-thiazolidinedione is a drug product that is used for the research and development of drugs. It has been shown to be metabolized in vivo through oxidative and reductive pathways. 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]-methylene]-2,4-thiazolidinedione has been found to have antimicrobial properties against Mycobacterium tuberculosis. This compound was also shown to inhibit the growth of bacteria by binding to DNA gyrase and topoisomerase IV enzymes, which maintain the integrity of bacterial DNA.</p>

<p>Please enquire for more information about Rosuvastatin impurity 42 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Bis(o-ethylbenzylamine) catechol dihydrochloride is a potent inhibitor of protein kinases that play a crucial role in the regulation of the cell cycle. It has been shown to induce apoptosis in various human cancer cell lines, including leukemia and Chinese hamster ovary cells. This compound inhibits the activity of several kinases, including indoleamine 2,3-dioxygenase (IDO), which is involved in tumor immune evasion. Bis(o-ethylbenzylamine) catechol dihydrochloride also acts as an inhibitor of other key proteins involved in the growth and proliferation of cancer cells. Its unique mode of action makes it a promising candidate for the development of novel anticancer therapies.

<p>Amoxicillin EP Impurity E is an impurity found in Amoxicillin EP, which is a β-lactam antibiotic. It belongs to the group of β-lactam antibiotics and has antibacterial activity. Amoxicillin EP Impurity E is found by applying validation methods to measure the concentration of this product. The analytical method used for this impurity is a wavelength measurement or a magnetic field measurement. This impurity can be determined using chromatographic or elution methods. The chromatographic methods used are high performance liquid chromatography (HPLC) and gas chromatography (GC). Method development is required for determining the level of this impurity, as well as validation procedures for measuring it with various methods.</p>

<p>6-Chloro-4-(2-chlorophenyl)-2-quinazolinecarboxylic acid (CA) is an impurity found in the drug lorazepam. It is a chemical intermediate that is not active as a pharmaceutical agent, but has been studied for use in treating epilepsy and other neurological disorders. CA is an excipient used to manufacture other drugs such as salicylic acid and the surfactant sodium lauryl sulfate. It has been shown to have acidic properties and can be used as a surfactant, which is helpful in chromatographic methods to separate molecules by size. CA also binds to chloride ions, which are necessary for the proper functioning of many cellular processes. CA's molecular weight is 322 daltons and it exhibits no pharmacological activity.</p>

<p>Pentalenolactone O is a natural product, which is used as an analytical standard for the determination of metabolites in drug development and research. It can be synthesized from pentalenolactone A by hydrogenation with Raney nickel catalyst. Pentalenolactone O is also a synthetic compound that has been developed as an impurity standard for HPLC analysis. The purity of this compound is high, and it complies with the requirements of pharmacopoeias such as USP and BP.</p>

2,6-Dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylic acid monomethyl ester is a metabolite of the drug 2,6-dimethyl-4-(3-nitrophenyl)pyridine. It has been shown to have an analytical purity greater than 98%. This compound is marketed as an HPLC standard and can be used as an impurity standard in the manufacture of a drug product. The CAS number for this compound is 64603-72-1.

2-Isopropoxy-5-phenyl-1,3,4-oxadiazole is a potent anticancer agent that has been extensively studied for its ability to inhibit tumor growth in humans. This compound belongs to the class of kinase inhibitors and has been shown to induce apoptosis in cancer cells. It is an analog of a medicinal compound that was first identified in Chinese herbal medicine. 2-Isopropoxy-5-phenyl-1,3,4-oxadiazole specifically inhibits certain protein kinases involved in cancer cell signaling pathways, leading to a decrease in cell proliferation and survival. This compound has demonstrated significant activity against various types of cancer cells and may have potential as a therapeutic agent for the treatment of cancer. Its presence can be detected in human urine after administration.

Avanafil 5'-desmethylpyrimidyl 5'-acid is a kinase inhibitor that has been shown to have anti-cancer properties. It inhibits kinases, which are enzymes involved in cell signaling pathways, and has been shown to inhibit the growth of cancer cells in vitro. Avanafil 5'-desmethylpyrimidyl 5'-acid may be used in combination with other drugs, such as rifampicin or methotrexate, for the treatment of cancer. Additionally, it has been found to induce apoptosis (programmed cell death) in human tumor cells. Chinese medicine has also used avanafil 5'-desmethylpyrimidyl 5'-acid analogs such as astaxanthin for its health benefits. This drug is excreted primarily through urine and shows promise as a potential inhibitor for various diseases.

<p>NMP-ACA is a metabolite of cefepime. It is a synthetic, impurity standard for use in HPLC. It has an analytical purity of &gt;98%. The metabolites of NMP-ACA are not known at this time.</p>

<p>Amoxicillin EP Impurity L is an impurity standard for amoxicillin. It is a synthetic compound that is used to ensure the quality of amoxicillin drug products. Amoxicillin EP Impurity L has been shown to be metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. This impurity has also been shown to have anti-inflammatory properties and may be due to its inhibition of prostaglandin synthesis.</p>