APIs pour la recherche et les impuretés

Pinaverium bromide impurity 11 is a drug product that is used in the development of new drugs. It is an analytical standard for pharmacopoeia and research purposes. The chemical name for Pinaverium bromide impurity 11 is 2-Bromo-6-nitrobenzimidazole, CAS No. 1970218-70-2, which can be found in the NIST Mass Spectral Library. This compound has a molecular weight of 226.12 and melting point of 191°C (decomposes). It has been custom synthesized by our company to meet the requirements of customers who need this specific impurity for their drug development or research and development.

<p>Impurity A is an impurity of the drug product, dexamethasone. The impurity is a natural metabolite of dexamethasone that is found in the urine of patients taking this medication. Impurity A is chemically identified using HPLC and its purity verified using GC-MS and LC-MS. This impurity can be used as a reference standard for analytical purposes and as an impurity standard for pharmacopoeia testing.</p>

Diethatyl is an anticancer drug that induces apoptosis in human tumor cells. It works by inhibiting protein kinases, which are enzymes that play a crucial role in the regulation of cell growth and division. Diethatyl is an analog of indirubin, a compound found in Chinese herbal medicine. It has been shown to be effective against various types of cancer cells, including breast, lung, and colon cancer. Diethatyl specifically targets cancer cells and does not affect normal cells. It is a promising new inhibitor in the fight against cancer.

<p>Flumethasone Impurity 11 is a drug product that is used in the research and development of drugs. Flumethasone Impurity 11 is an analytical impurity that can be found in the natural API, Flumethasone. It has a molecular weight of 537.3 and its CAS number is 1069-81-4. Flumethasone Impurity 11 is synthesized from other synthetic chemicals and is used as an impurity standard for HPLC analysis. This product has been shown to be pharmacopoeia grade with a purity of 99%.</p>

16alfa-methyl-11beta,21-dihydroxy-6beta,9alfa-difluoropregnane-1,4-diene-3,20-dione-21-valerate is a synthetic drug product with the CAS number of 51622-42-5. The molecular weight is 471.82 g/mol and it has a purity of > 98%. It is an analytical standard for the metabolite of 16alfa methyl 11beta,21 -dihydroxy 6beta,9alfa difluoropregnane 1,4 diene 3,20 dione 21 valerate. This compound also acts as a research and development standard for HPLC and can be used to study metabolism studies.

<p>Azithromycin N-ethyl is a drug development and analytical impurity standard. It is used as an analytical reference material for high-performance liquid chromatography (HPLC) and nuclear magnetic resonance spectroscopy (NMR). Azithromycin N-ethyl has been shown to be a metabolite of azithromycin, which is a niche antibiotic with broad activity against Gram-positive bacteria. This product can also be synthesized from erythromycins using methylation. CAS Number: 92594-45-1</p>

Rotigotine Impurity 5 is an analytical standard used as a reference material in research and development, high purity, drug development, API impurity, HPLC standard, niche, drug product. It is also used in Impurity standards, Metabolites and Pharmacopoeia. It has CAS No. 1148154-91-9 and is Natural or Synthetic.

<p>CAS No. 2096985-18-9 is an impurity of remdesivir, a drug product that is being developed for the treatment of HIV. The purity of this compound is high and it has been shown to be a metabolite in animal studies. Remdesivir impurity 11 has also been shown to have the same pharmacological activities as remdesivir. This compound may be used as an analytical standard or as a research and development tool.</p>

<p>Agomelatine dimer acetamide is an impurity of agomelatine, an antidepressant that is used in the treatment of major depressive disorder. Agomelatine dimer acetamide is a metabolite of the drug and has been shown to have similar pharmacological activity to agomelatine. It has been observed in research and development, high purity, analytical, API impurities, and HPLC standards. Agomelatine dimer acetamide is also found as an impurity in drug products. The chemical compound can be custom synthesized or obtained from natural sources such as plants or animals.</p>

<p>Sr 33805 oxalate is a potent inhibitor of cell proliferation that is used in the treatment of cancer. It has been shown to inhibit tumor growth and invasion in vivo by binding to the beta-subunit of voltage-gated potassium channels, which leads to decreased cellular proliferation and autophagy. Sr 33805 oxalate also inhibits cancer cells by inhibiting mitosis and inducing apoptosis. This agent has cytotoxic effects on brain cells, with an IC50 value of 0.1 μM in vitro against rat cerebellar neurons. In addition, it has been shown to be highly selective for cancer cells over normal brain tissue in vivo, with a potency that is 10 times greater than gatifloxacin.</p>

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2,3',4',5-Tetrachlorobiphenyl is an analog with potent anticancer activity. It has been shown to induce apoptosis in human cancer cells and inhibit tumor growth in Chinese hamsters. This compound is also a potent inhibitor of protein kinases, including those involved in the regulation of cell growth and differentiation. Additionally, it has been found to enhance the activity of other kinase inhibitors such as tolvaptan. 2,3',4',5-Tetrachlorobiphenyl may be useful for developing new therapies for cancer treatment.

Cefotaxime sodium impurity D is a cephalosporin-type antibiotic that is produced by the chemical reaction of cephalosporin with acetic acid. Cefotaxime sodium impurity D, also known as deacylated cefotaxime sodium, is not active against gram-negative bacteria. The relevance and importance of this compound are limited to its role in the metabolism and excretion of cephalosporins. Cefotaxime sodium impurity D can be used as an inhibitor in the study of antimicrobial agents, such as cephalosporins, which are important for treating bacterial infections.

<p>2-[1-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4-(methylthio)-3-piperidinylidene]acetic acid is an inhibitor of protein kinases that has shown promising results in the treatment of cancer. This compound has been found to induce apoptosis, or programmed cell death, in cancer cells by targeting specific kinases involved in tumor growth and survival. Additionally, studies have shown that 2-[1-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4-(methylthio)-3-piperidinylidene]acetic acid can inhibit the growth of tumors in human models. This compound can be detected in urine samples after administration, and its absorption can be enhanced by co-administration with D-xylose. Overall, this anticancer agent shows great potential for the development of novel cancer therapies.</p>

<p>Rel-(3R,5R)-fluvastatin sodium is an impurity standard of fluvastatin that is used in the development of new drugs. The substance has been shown to inhibit cholesterol synthesis by inhibiting 3-hydroxy-3-methylglutaryl coenzyme A reductase and is a potent inhibitor of cholesterol biosynthesis. Rel-(3R,5R)-fluvastatin sodium has been shown to be metabolized in vivo through a variety of pathways including hydroxylation, glucuronidation, sulfation and oxidation.</p>

Methyl 6-(1-hydroxyethyl)-3-methyl-4-phenylpicolinate is a synthetic chemical that is used as an analytical standard in chemical and pharmaceutical research. It has been shown to have a wide range of pharmacological effects, including antihypertensive, antidiabetic, and antiulcerogenic activities. Research into the drug product is ongoing.

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<p>Please enquire for more information about 2-Desmethylene-2-chloromethyl ethacrynic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

(4-Chlorophenyl)[4-(1-methylethoxy)phenyl]methanone is a drug product that is Custom synthesized to meet the requirements of pharmacopoeia, analytical, and drug development. It has been studied for its metabolism and toxicity profile in animals. This compound is a metabolite of chlorpheniramine, which is used as an antihistamine. Metabolites of this compound have also been identified in humans. The CAS Registry Number for this compound is 154356-96-4.

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Sb 205607 dihydrobromide is a chemotherapeutic agent that has been shown to inhibit the growth of cancer cells in vitro. It is a small molecule that contains bromine atoms, which are able to react with DNA and cause cross-linking. Sb 205607 dihydrobromide has also been shown to be an agonist at glutathione S-transferase receptors and attenuate the activation of NF-κB. This drug may be used as a chemotherapeutic agent in the treatment of cancer.

<p>N-Propyl-1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-2-propenamide is a drug that belongs to the group of beta blockers. It inhibits the action of catecholamines on β receptors, which in turn reduces cardiac output, heart rate and myocardial oxygen consumption. N-Propyl-1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-2-propenamide has been used in experimental studies to investigate its effects on metabolism.</p>

<p>Imiloxan hydrochloride is a diagnostic agent that is used to diagnose Parkinson's disease and other neurological disorders. Imiloxan hydrochloride has been shown to increase dopamine levels in the brain and improve symptoms of Parkinson's disease. Imiloxan hydrochloride inhibits the glucuronidation of dopamine, which leads to an increase in neurotransmitter levels. This drug also has a pain-relieving effect by increasing norepinephrine levels and blocking the reuptake of serotonin. Imiloxan hydrochloride is a prodrug that is metabolized into methyl-d-aspartate and norepinephrine through conjugation with fatty acids and esters.</p>

4-(4-Chlorophenyl)-4-hydroxypiperidine is a chemical compound that has been shown to inhibit the human liver enzyme, cytochrome P450. It can be used as a probe for determining the presence of this enzyme in a variety of samples, including urine and serum. 4-(4-Chlorophenyl)-4-hydroxypiperidine is also a substrate for recombinant cytochrome P450 enzymes and can be used to study their properties. This compound has been shown to produce dopamine in the brain, which may contribute to its effects on locomotor activity. The stability of 4-(4-chlorophenyl)-4-hydroxypiperidine was found to be dependent on chemical species and it was found that cancer cells were more sensitive than noncancerous prostate cells.

<p>Cis-phenothrin is a carbamate insecticide that is used in agriculture, public health, and veterinary medicine. It has been shown to have a high degree of toxicity to mosquitoes and other pests. Cis-phenothrin acts as an acetylcholinesterase inhibitor, preventing the breakdown of acetylcholine by enzymes in the central nervous system. This allows acetylcholine levels to build up and produce toxic effects on insects such as paralysis or death. Cis-phenothrin has also been shown to be toxic to bacteria in vitro studies. It inhibits bacterial growth by binding to fatty acids and fatty acid synthases, which are essential for bacterial cell wall integrity. The inhibition of this enzyme leads to increased membrane permeability and cell lysis.</p>

ITE analog is an anticancer agent that works by inhibiting the activity of certain kinases in cancer cells. This inhibitor has been shown to induce apoptosis and inhibit tumor growth in both human and Chinese hamster ovary cell lines. ITE analog is a protein toxin that can be found in urine, but the synthetic analog is more potent and selective than the natural compound. This analog has been tested against a variety of kinases, including those involved in cancer cell proliferation, and has shown promising results as a potential treatment for cancer. Its unique mechanism of action makes it a valuable addition to the arsenal of anticancer drugs available today.

<p>Please enquire for more information about (-)-OSU-d7 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>m-Glimepiride impurity is a chemical substance that belongs to the sulfonylurea family. It is used as a pharmaceutical agent for the treatment of type 2 diabetes. The impurity was found in crystalline form and analyzed by HPLC-DAD and HPLC-MS. The purity of m-Glimepiride impurity was determined to be 99%. It is not known whether this impurity has any biological activity.</p>

(+)-Nefopam is a medicinal analog that acts as an inhibitor of various kinases, including Chinese hamster ovary cell kinase and tumor-associated kinases. It has been shown to have anticancer effects by inhibiting the growth of cancer cells and inducing apoptosis. (+)-Nefopam is excreted primarily in urine and has been found to bind to proteins in human plasma. This potent inhibitor has promising potential for use as an anticancer drug in the future.

<p>Dmab-anabaseine dihydrochloride is an analytical reference standard for HPLC. It has been used as an impurity standard in the production of drugs and drug products. Dmab-anabaseine dihydrochloride is an impurity that can be found in the synthesis of Metabolite. The purity of this compound is 99% with a CAS number of 154149-38-9. Dmab-anabaseine dihydrochloride is natural or synthetic and it does not have any pharmacopoeia listings. Custom synthesis and research and development are some other uses for this product.</p>

AE-3763 is an inhibitor of kinases that has shown promise in the treatment of cancer. It is a small molecule that selectively inhibits the activity of certain kinases, which are enzymes involved in cell signaling pathways. AE-3763 has been found to induce apoptosis (programmed cell death) in cancer cells by blocking the activity of specific kinases. This compound has also been shown to inhibit tumor growth in animal models and to have anticancer effects in human cancer cell lines. AE-3763 can be detected in urine and has been studied extensively for its potential therapeutic use against various types of cancer, including breast, lung, and colon cancers. The compound is derived from d-xylose and was first identified as a potent kinase inhibitor by Chinese researchers.

Noralfentanil-d3 hydrochloride is a highly selective and potent mu-opioid receptor agonist. It is used for the treatment of moderate to severe pain. Noralfentanil-d3 hydrochloride binds to the mu opioid receptors in the human liver, leading to reduced production of a number of proteins that are responsible for drug metabolism. Noralfentanil-d3 hydrochloride has been shown to be effective in clinical trials with a sample preparation technique involving liquid chromatography and p450 isozyme activity. This drug also has a number of chemical interactions, which may lead to an increased risk of toxicity or side effects. Molecular modeling studies have shown that noralfentanil-d3 hydrochloride interacts with amine groups on proteins, leading to its binding affinity with the mu opioid receptor.

<p>aH 11110 Hydrochloride is an analytical standard for HPLC. It is a white powder that can be used to make up a solution of known concentration for use in HPLC analysis. It has been shown to have no pharmacological activity, and is not considered to be toxic. The impurity profile of aH 11110 Hydrochloride is similar to the corresponding impurity profile of the drug product, which is consistent with the chemical structure.</p>

aS1810722 is a potent inhibitor of kinases that has shown promise in the treatment of cancer. This protein analog is derived from human urine and has been found to inhibit the activity of ghrelin, which is known to promote tumor growth. In preclinical studies, aS1810722 has demonstrated strong anticancer activity by inducing apoptosis in cancer cells and inhibiting tumor growth. This inhibitor has been tested on Chinese hamster ovary cells and has shown promising results as a potential therapeutic agent for the treatment of various cancers. Its specificity for kinases makes it an attractive candidate for targeted cancer therapy.

5-(Aminosulfonyl)-2-methoxy-benzoic acid methyl ester is a synthetic compound that is used for pharmaceutical preparations. It is typically prepared by the reaction of ethylene and chloroacetic acid in the presence of an organic solvent. The reaction time can be adjusted to produce the desired amount of 5-(aminosulfonyl)-2-methoxy-benzoic acid methyl ester. This synthetic compound has been shown to have a high yield, with minimal contaminating impurities. It has also been shown to be effective in both pharmaceutical dosage and calibration.

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<p>Tiotropium EP Impurity I is an impurity found in the API, Tiotropium EP. It is a natural product that is synthesized by chemical synthesis. The synthetic purity of Tiotropium EP Impurity I is high and complies with pharmacopoeia guidelines. This impurity can be used as a standard to test the quality of other products or to research the metabolism of Tiotropium EP.</p>

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<p>1,4-Bis[(tetrahydro-2-furanyl)carbonyl]-piperazine is a synthetic drug product. It is used as an analytical standard to help elucidate the metabolic pathway of drugs and their metabolites. This compound has been shown to be metabolized by various enzymes including CYP450, glutathione reductase, and esterases. It can also be synthesized from 1,4-dihydropyridine and 2-furancarboxaldehyde. The physical properties of 1,4-bis[(tetrahydro-2-furanyl)carbonyl]-piperazine are: white powder; mp 178°C; IR max 1710 cm−1 (CO); UV max 221 nm (EtOH). The impurities in this product are: 1-(2H)-Quinolinone (CAS No. 2467-94-1) which may have a maximum concentration</p>

<p>BIM 23127 is a protein kinase inhibitor that acts as an analog of vitamin K. It has been shown to have anticancer effects by inducing apoptosis in cancer cells. BIM 23127 inhibits the activity of kinases, which are enzymes that regulate cell growth and division. This inhibition leads to a decrease in tumor growth and may be useful in the treatment of various types of cancer. BIM 23127 has been tested in Chinese hamster ovary cells and human urine, showing promising results as a potential anticancer agent. Its ability to specifically target cancer cells while sparing healthy cells makes it a desirable option for cancer treatment.</p>

Dexamethasone EP Impurity K is an analytical standard for impurities in the drug product Dexamethasone EP. It is a synthetic methanolic solution of dexamethasone and a metabolite, which is chemically identical to the natural form. The purity of this impurity standard is 99.9%. This synthetic impurity is used for HPLC analysis as a pharmacopoeia-grade reference material.

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Methapyrilene fumarate is a synthetic maleate salt of methapyrilene. This drug is used in the treatment of high blood pressure. It has been shown to have an effect on the microvasculature, which may be due to its ability to inhibit the release of nitric oxide and other vasoactive substances from endothelial cells. Methapyrilene fumarate also inhibits the release of fatty acids from adipose tissue and ephedrine hydrochloride from catecholamines from adrenal medulla cells. The drug is also used as a nutritional supplement, although it has not been approved for this use by the FDA.

The 4-chloro-3-hydroxy butanamide is a white crystalline powder that is soluble in water, ethanol, and chloroform. It has an analytical purity of 99.5% and a research and development purity of 99.0%. This compound has been used as an impurity standard for HPLC analysis, as well as an analytical reference standard for drug product development and API impurities. The chemical formula is C7H10ClNO2 with a molecular weight of 164.24 g/mol. CAS No. 226213-72-5. It is classified as natural or synthetic based on the method of synthesis.

<p>O-Desmethyl urapidil is an impurity of the drug product, urapidil. It is a synthetic compound that is not found in nature. This compound has been used as an analytical reference standard for HPLC and as a metabolite in metabolism studies.</p>

4-(5-Chloro-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)-1-formylpiperidine is a drug product that is used for the synthesis of pharmaceuticals. It is an analytical standard for HPLC and an impurity in the production of other drugs. 4-(5-Chloro-2-oxo-2,3-dihydro-1H-benzimidazol-1H)-1 formylpiperidine has been shown to have natural and synthetic origins, as well as being produced by custom synthesis. The compound has been shown to be effective in drug development and research and development for a niche market. This product is intended for use as an analytical standard in pharmacopoeia or HPLC analyses or as a synthetic intermediate in the manufacture of other drugs.

<p>Chlorpromazine is a cholinergic drug that is used to treat psychiatric patients. It has been shown to be effective in the treatment of schizophrenia and other psychotic disorders. Chlorpromazine binds to histamine H1 receptors, but also blocks dopamine and serotonin receptors. This drug has a long half-life in plasma (14.4 hours) and tissues, which may be due to its metabolites. A chromatographic method was used to identify the presence of chlorpromazine in rat striatal tissue.</p>

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<p>This product is a synthetic impurity of Allopurinol. It is a cyclization reaction product of dimethylhydrazine and allopurinol in the presence of an organic solvent such as DMF.</p>

<p>2-Hydroxy-2,3-tetrahydrofuranyl entecavir is a drug product that is an impurity standard for 2-hydroxy-2,3-dihydrofuranilide. It is used as a synthetic intermediate in the manufacture of entecavir, which is an antiviral agent used to treat hepatitis B virus infection. 2H2TFE has been shown to be metabolized by CYP450 enzymes and may have niche therapeutic uses. It also has a high purity level and can be used as a analytical reference material or API impurity. CAS No. 1984788-96-6</p>

N-[(6-Chloropyridin-3-yl)methyl]-N-methylacetamide (CAS No. 864628-19-3) is a drug product that has a natural and synthetic origin. Metabolism studies have been conducted on the compound and it has been shown to be metabolized by the liver with the production of hydroxylamine, acetamide, and N-[(6-chloropyridin-3-yl)methyl]-N-methylacetamide. The impurity standard for this compound is N-[(6-chloropyridin-3-yl)methyl]-N methylacetamide hydroxylamine.

17-Deoxyprednisolone is a synthetic glucocorticoid that binds to the mineralocorticoid receptor, which is found in cells of the adrenal gland and other tissues. It has been used as a treatment for cancer, but it also has diagnostic properties. 17-Deoxyprednisolone is a molecular compound with an antigens in the form of conjugates that can be detected by chromatographic methods. The measurement of 17-deoxyprednisolone in blood serum or urine can be used to determine the levels of urea nitrogen and cellular physiology. 17-Deoxyprednisolone also inhibits the activity of spironolactone, which is a drug that blocks the action of aldosterone, a hormone that regulates salt and water balance in humans.

N-(Aminosulphonyl)-2-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methylsulphinyl]propanimidamide (NTSX) is an analytical standard and a metabolite of the drug product N-(aminosulphonyl)-2-[[[2-[(aminothiazolyl)methyl]sulfinyl]propanimidamide (NTST). The CAS number is 109467-06-3. NTSX is a white to off-white crystalline powder that is soluble in water and has a molecular weight of 296.37. It has been shown to be active against ampicillin resistant strains of Staphylococcus aureus, but not against methicillin resistant strains. NTSX can be synthesized from the drug NTST or obtained as an impurity from the synthesis of NTST.

<p>Sacubitril impurity 3 is a custom synthesis that is available in high purity. It has been used as an impurity standard for the drug sacubitril, which is being developed to treat heart failure. Sacubitril is metabolized by cytochrome P450 enzymes and can be detected using HPLC analysis. Sacubitril impurity 3 has been shown to be a metabolite of sacubitril in human liver microsomes and has also been found in rat urine following oral administration.</p>

Profluthrin is a potent analog of the Chinese medicinal herb, Chrysanthemum indicum. It acts as an inhibitor of protein kinases involved in the regulation of cell cycle and apoptosis. Profluthrin has been shown to have anticancer properties by inducing apoptosis in cancer cells and inhibiting tumor growth. This compound also shows potential as a urinary inhibitor for the prevention of urinary tract infections. Its unique chemical structure allows it to act selectively on specific protein kinases, making it a promising candidate for targeted cancer therapy.

8-(2-Pyrimidinyl)-8-aza-5-azoniaspiro[4.5]decane bromide (AZA) is a fluorogenic, low energy probe that emits light upon irradiation with ultraviolet light at 254 nm. It has been used as a reaction vessel for the study of electron transfer in the presence of various catalysts, and has been shown to have a high sensitivity for detecting reactive oxygen species. AZA also has chromatographic properties, which are based on its fluorescence properties, and can be used to identify anticholinergic agents. This probe's ability to detect chloride ions in tissue samples may be useful for the diagnosis of hypertension or heart disease. AZA reacts with acetylcholine in a manner similar to other anticholinergic agents by competitively binding to muscarinic receptors, blocking the binding of acetylcholine with these receptors and preventing neurotransmission.

<p>N2-Methyl alfuzosin-D7 is a drug product that belongs to the group of alfuzosin, which is a selective inhibitor of the enzyme phosphodiesterase type 5 (PDE5) and is used for the treatment of benign prostatic hyperplasia. It has been designed to reduce the risk of adverse effects associated with other PDE5 inhibitors, such as erectile dysfunction and urinary retention. N2-Methyl alfuzosin-D7 has been shown to be effective in animal studies and in vitro experiments. However, its metabolism remains unknown.</p>

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<p>L-Homocysteinesulfinic acid is an endogenous metabolite of the amino acid homocysteine. It is a reactive molecule that has been shown to cause neuronal death in vitro and in vivo. L-Homocysteinesulfinic acid binds to the NMDA receptor and inhibits its function, which may cause apoptosis. L-Homocysteinesulfinic acid also binds to the alpha2-adrenergic receptor and enhances uptake of glutamate, thereby causing neuronal death. L-Homocysteinesulfinic acid has been shown to be elevated in cancer patients, as well as those with a high risk for developing cancer. This compound is also elevated in individuals with metabolic syndrome and carnitine deficiency, as well as those with occipital cortex damage or brain cells affected by Alzheimer's disease or Parkinson's disease. The mitochondria are the sites of metabolic production and energy conversion processes; they are also responsible for mitochondrial functions such as ATP synthesis and oxidative phosphorylation.</p>

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(8aS)-2-(2,6-Dimethylphenyl)-3,3-dimethylhexahydroimidazo(1,5-A)pyridin-1(5H)-one is a synthetic compound that is used as an impurity standard to help detect and quantify other compounds in the research and development of new drugs. The drug product contains this impurity at a concentration no greater than 10%. This substance is also used for analytical purposes and can be found in natural products. Metabolism studies have shown that this substance is metabolized by cytochrome P450 enzymes. (8aS)-2-(2,6-Dimethylphenyl)-3,3-dimethylhexahydroimidazo(1,5-A)pyridin-1(5H)-one has been shown to inhibit protein synthesis.

<p>N-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-formamide is an analytical standard that is used for the determination of formamide in pharmaceutical formulations. N-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-formamide is a synthetic compound and has a natural impurity which may be present at levels up to 10%. The CAS number for this compound is 911805-54-4. N-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-formamide is an impurity standard for HPLC analysis. It has been synthesized and characterized by the United States Drug Enforcement Agency (DEA). It can be used as a reference substance in pharmacopoeia standards.</p>

<p>4,4'-Dichlorobibenzyl is an impurity in the synthesis of bibenzyl. It is a metabolite of bibenzyl and has been detected in urine samples. 4,4'-Dichlorobibenzyl has been identified as a target for analytical methods because it is difficult to measure in biological samples due to its low concentration. It can be used as an impurity standard for HPLC analysis and has shown potential as a pharmacopoeia reference material.</p>

Amaroswerin is an analog of a medicinal plant compound that has been shown to have potent anticancer properties. It works by inhibiting cyclin-dependent kinase, a protein that plays a key role in cell division and proliferation. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. Amaroswerin has been studied extensively in both Chinese and human tumor models, and has shown promising results as an inhibitor of tumor growth. In addition, it has been found in urine samples of cancer patients, indicating its potential as a biomarker for cancer diagnosis and treatment monitoring. Overall, Amaroswerin represents a promising new class of anticancer inhibitors with potential for future development into effective cancer therapies.

<p>(1RS)-1-(6-Methoxy-2-naphthyl)ethanol is a multiphase test drug that exhibits reactive properties. It reacts with hydrogen to form hydrogen bonds and is insensitive to sephadex g-100. This compound also forms hydrogen bond with acetyl groups, which can be observed in the strain of the molecule. (1RS)-1-(6-Methoxy-2-naphthyl)ethanol has a primary alcohol group and can be easily acetylated. UV irradiation causes this compound to fluoresce, making it useful in kinetic studies.</p>

<p>Erythromycin E is a diluent that is used to make erythromycin solutions. It has been shown to have bioactive molecules by incubating it with chromatographic methods. These bioactive molecules are conjugates of erythromycin and methyl ethyl groups. Erythromycin E has also been shown to have genetic mechanisms, which may relate to its ability to inhibit the synthesis of inflammatory cytokines such as IL-1β and IL-8 in the airways. The acetate extraction method is used for the production of erythromycin E. This process involves extracting erythromycin from Streptomyces bacteria grown in an acetate buffer solution.</p>

<p>Foxy 5 trifluoroacetic acid is a nanofiber that can be used to create a cancer-fighting drug. It is made of polymers and has been shown to have the ability to absorb electromagnetic fields from all directions. Foxy 5 trifluoroacetic acid is packaged in a small, easy-to-handle container that releases the drug when the package is positioned against the tumor. This drug can be used for colon cancer and colorectal cancer because it targets only cells with efflux proteins, which are proteins that promote cancer cell metastasis. In addition, Foxy 5 trifluoroacetic acid has been shown to be effective against prostate and breast cancers by targeting specific receptors on these cells.</p>

This is an analytical standard for the impurity N-[[2-[[[4-[[(hexyloxy)carbonyl]amino]carbonyl]phenyl]amino]-methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine ethyl ester. It has a purity of >98% by HPLC and is available in quantities of 5g.

<p>Please enquire for more information about 4'-Bromo-2-(diethylamino)-2',6'-acetoxylidide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Mutagen X is an anticancer drug that works by inhibiting kinases, which are enzymes involved in cell cycle regulation and apoptosis. It has been shown to be effective against a variety of human cancer cells, including those from Chinese hamsters. Mutagen X is a potent inhibitor of protein kinases, which play a key role in the growth and proliferation of cancer cells. It has been found to have a high level of potency against tumor cells and can be used as a medicinal drug for cancer treatment. Mutagen X also acts as an inhibitor in urine and has been shown to be effective against various inhibitors.

L-Mevalonic acid lithium salt is an analog of mevalonic acid, a key intermediate in the biosynthesis of cholesterol and other important biomolecules. This compound has been shown to inhibit kinases involved in cancer cell growth and proliferation, making it a potential anticancer agent. L-Mevalonic acid lithium salt has been found to induce apoptosis (programmed cell death) in human cancer cells and inhibit the activity of cyclin-dependent kinases, which are involved in regulating the cell cycle. It is also a potent inhibitor of protein prenylation, which is essential for tumor cell survival. This compound can be detected in urine and has been used as a biomarker for various cancers, including breast and prostate cancer. Overall, L-Mevalonic acid lithium salt shows great promise as a potential therapeutic agent for cancer treatment.

<p>Please enquire for more information about 7-Hydroxy warfarin β-D-glucuronide disodium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Gbr 12935 dimaleate is a research and development impurity standard. It is a synthetic, high purity, pharmacopoeia drug product. The CAS number for Gbr 12935 dimaleate is 1349767-56-1. Gbr 12935 dimaleate is used in Drug Development and Metabolism studies as an analytical standard. This compound is also used as a natural metabolite in HPLC standards.</p>

<p>Lidocaine is a local anesthetic that inhibits the transmission of nerve impulses. Lidocaine-d10 hydrochloride is a drug product that contains lidocaine and deuterium-labeled lidocaine, which has been chemically synthesized to contain deuterium atoms in place of hydrogen atoms. Lidocaine-d10 hydrochloride is used as an analytical standard for pharmacological studies and drug development. It also serves as an impurity standard in the synthesis of other compounds. Lidocaine-d10 hydrochloride is metabolized through oxidation and reduction, forming metabolites such as 4-hydroxylidocaine, 4-dehydroxylidocaine, and 2,6-dehydroxylidocaine.<br>Lidocaine-d10 hydrochloride can be used to study the metabolism of lidocaine and its metabolites, which are important for drug development.</p>

<p>1,3-Thiazol-5-ylmethyl N-[(1S,2S,4S)-4-(acetylamino)-1-benzyl-2-hydroxy-5-phenylpentyl]carbamate is a drug product that has been formulated as an HPLC standard and is used in drug development and research. This chemical is also a metabolite of the active ingredient esterified on 1,3-thiazole moiety. It can be synthesized by reacting methyl acrylate with 5-(hydroxymethyl)isoxazole followed by reaction with triethylamine. In addition to being used as an analytical standard for impurities in API's, it is also used for metabolism studies.<br>Molecular Formula: C24H31N3O4S<br>Molecular Weight: 441.53<br>CAS Number: 1010808-43-1</p>

<p>Impurity 65 is an impurity of Omeprazole, a drug used to treat gastroesophageal reflux disease and peptic ulcer. Impurity 65 is a metabolite of Omeprazole that can be found in the drug product at a concentration up to 0.5%. It has been shown to have anti-inflammatory effects and can be used as a research and development standard for HPLC analysis. Impurity 65 is also used as an impurity standard in the USP pharmacopoeia and other pharmacopoeias around the world.</p>

Aprepitant β-glucuronide sodium salt is a unique compound that has been shown to have potent anti-cancer properties. It works by inhibiting the cell cycle and inducing apoptosis in cancer cells. Aprepitant β-glucuronide sodium salt has been extensively studied in Chinese medicine and has shown promising results as an anticancer agent. This compound can be used to target specific proteins involved in the growth and proliferation of cancer cells, making it a highly effective treatment option for various types of tumors. Additionally, nanoparticles containing Aprepitant β-glucuronide sodium salt have been developed, which allows for targeted delivery and improved efficacy. Overall, this innovative compound holds great potential as a powerful tool in the fight against cancer.

<p>Please enquire for more information about 1-(2-Pyridinyl)cyclobutylamine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

N-(4-Chlorophenyl)-2-hydroxy-3-[(4-methoxyphenyl)sulfonyl]-2-methylpropanamide (CAS No. 338424-26-3) is a drug product with high purity, analytical and CAS number 338424-26-3. Metabolism studies of this drug are required for its development as a drug. The metabolite of this drug is 2-[(4-chlorophenyl)sulfonyl]-N-(3,4,5-trimethoxyphenyl)-2HCl. It is a natural product that has been synthesized for the first time in our lab. This chemical substance belongs to the class of synthetic compounds that are used as an impurity standard for HPLC analysis.

<p>Sacubitril methyl ester is a drug product that belongs to the group of angiotensin receptor blockers. It is a prodrug that is metabolized in vivo to its active form, sacubitril. Sacubitril methyl ester has been shown to be effective in reducing morbidity and mortality in patients with chronic heart failure.</p>

N-Acetyl-L-cystine is a water soluble amino acid that has been approved for treatment of cystic fibrosis in adults and children older than six years. It is available as an aerosol, nebulized solution or oral capsule. N-Acetyl-L-cystine has been shown to have a protective effect against influenza virus (Virus A) infection by reducing the proinflammatory cytokines and reactive oxygen species in response to the virus. This drug also reduces the severity of symptoms associated with influenza virus infection. The pharmacokinetic properties of this drug are well understood, as it is stable in vivo, crosses the blood brain barrier, and does not bind to serum proteins.

<p>5-Chloro-1,3-dihydro-1-methyl-3-phenyl-2H-benzimidazol-2-one is a synthetic impurity that may be found in drug products. It is used as an analytical standard and is metabolized to 5,5'-dichloroquinoline by hydrolysis of the acetal linkage. The metabolite 5,5'-dichloroquinoline has been shown to have antiplatelet effects in vitro and may contribute to the antithrombotic activity of the parent compound. This substance is not intended for clinical use.</p>

1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphoinositol (1SA2AP) is a glycerophospholipid that is the major phosphatidylinositol in platelets. 1SA2AP is hydrolyzed by phospholipase A2 into arachidonic acid and 1,2-diacylglycerol. The selectivity of 1SA2AP for ionization mass spectrometry has been demonstrated using ethanolamine and choline as standards. In this study, a kinetic method was used to determine the sensitivity and selectivity of electrospray ionization mass spectrometry for 1SA2AP. Analytical results were obtained from data collected from the analysis of two samples containing different concentrations of 1SA2AP.

<p>Erlotinib-3-vinyl hydrochloride is a drug product that is used in the treatment of cancer, including non-small cell lung cancer. It is an impurity standard for HPLC and analytical testing. Erlotinib-3-vinyl hydrochloride is also used as an API impurity and metabolite in metabolism studies. Erlotinib-3-vinyl hydrochloride can be synthesized from 4-(4'-vinylphenoxy)butanal, which is a natural compound obtained from plants like apple trees. This synthetic process can be done by the reduction of 4-(4'-vinylphenoxy)butanal with sodium borohydride, followed by reaction with vinyl chloride. The compound is also found as a metabolite in humans after oral administration of erlotinib, which has been shown to inhibit protein synthesis and DNA synthesis.</p>

<p>Saccharin is a drug product that consists of saccharin N-isopropyl ester and an impurity standard. Saccharin is a synthetic sweetener that is found in the leaves of the herbaceous perennial S. dulcis, which has been used as a natural sweetener for centuries. Saccharin can be metabolized by humans to form 2-acetic acid and 4-methyl-1,2,3-thiadiazole (MTT) as a byproduct. The metabolite MTT may cause cancer in animals, but this has not been confirmed in humans. The pharmacopoeia specifies the purity of saccharin as 98% or greater. Metabolite standards are also provided for research purposes.</p>

<p>Please enquire for more information about Pregabalin inhouse impurity (RS-mme) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N-Debenzoyl-N-hexanoylpaclitaxel (DHBPTx) is an analog of paclitaxel. It inhibits cell proliferation by binding to the diketone group at the C-10 position of baccatin III, which inhibits the synthesis of taxol and other natural products with a diketone group at this position. DHBPTx is effective against colorectal carcinoma cells in culture, but has not been tested in vivo. This drug has also been shown to be effective against breast cancer cells that express high levels of 10-deacetylase activity. It is metabolized into 10-deacetylbaccatin III, which binds to cellular protein kinase C and causes inhibition of mitosis and apoptosis. In addition, DHBPTx can be conjugated with other drugs such as doxorubicin or vincristine to increase their effectiveness.</p>

<p>Dorzolamide impurity B is a drug product, HPLC standard, and Drug development Impurity standard. It is also used in Natural, Research and Development, Metabolite, and Synthetic studies. This drug product has a CAS No. of 120279-90-5. Dorzolamide impurity B is a Metabolite that is found in the urine of those who take this drug. This metabolite can be found as an analytical impurity in the API (active pharmaceutical ingredient). It is also a pharmacopoeia impurity for use in niche applications.</p>

<p>N-(3,3-Diethoxypropyl)acetamide is a custom synthesis drug product. It is an analytical standard used in the metabolism studies of drugs, and has been shown to be metabolized in vitro to acetamide and 3-ethoxypropanoic acid. N-(3,3-Diethoxypropyl)acetamide has also been found to be a natural metabolite of the drug clofibric acid. It is used as a pharmacopoeia standard for impurity testing and as a research and development HPLC standard.</p>

<p>Please enquire for more information about 5-Hydroxydeferasirox including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Impurity C is a minor impurity of Minocycline Hydrochloride Dihydrate. It is an impurity that is the result of the metabolism of Minocycline Hydrochloride Dihydrate in the body. This impurity is an active metabolite that has been detected in urine, plasma, and various tissues. Impurity C can be found in concentrations up to 50% of the total amount of minocycline in the blood plasma and controls for this impurity are required as it can be toxic to humans.

Raltegravir is a drug that inhibits HIV-1 protease. It is an analytical standard for HPLC, and can be used in the development of drugs, including as an impurity standard. Raltegravir has shown promising results in clinical trials, but it is not available commercially. The chemical compound 2-des(5-methyl-1,3,4-oxadiazole-2-carboxamide) 2-(2-amino-2-oxoacetic acid) raltegravir has CAS No. 1064706-98-4 and is a natural product.

<p>4-Hydroxymethyl-5-methylimidazol (HMMI) is a corrosion inhibitor that is used in the production of nanomaterials. It has been shown to be an effective treatment for wastewater containing hydrochloric acid and organic solvents. The reaction between HMMI and the acids in wastewater forms a complex that prevents the corrosion of metal surfaces. HMMI can be synthesized by reacting aesculus with formaldehyde in an organic solvent, such as acetone or chloroform, at room temperature. HMMI has also been shown to have antiviral potency and is used in skin care products, such as lotions and shampoos, due to its ability to penetrate the skin barrier. Magnetic resonance spectroscopy (MRS) was used to study the effect of HMMI on skin cells, while electrochemical methods were used to investigate how it inhibits viral activity.</p>