APIs pour la recherche et les impuretés

<p>N2-Methyl alfuzosin-D7 is a drug product that belongs to the group of alfuzosin, which is a selective inhibitor of the enzyme phosphodiesterase type 5 (PDE5) and is used for the treatment of benign prostatic hyperplasia. It has been designed to reduce the risk of adverse effects associated with other PDE5 inhibitors, such as erectile dysfunction and urinary retention. N2-Methyl alfuzosin-D7 has been shown to be effective in animal studies and in vitro experiments. However, its metabolism remains unknown.</p>

<p>2-[3-[4-(3-Chloro-4-ethylphenyl)-1-piperazinyl]propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one is a research and development impurity standard. Impurities are the substances that are not intentionally added to the drug product but can be generated from the synthesis process or from the raw materials. This substance has been used as a synthetic intermediate in the production of other drugs and as an analytical reference for HPLC analysis. It is used to help develop new drugs by providing data about metabolites and possible toxic effects on humans.</p>

<p>Acyclovir Impurity K is a drug product that is used as an analytical reference standard for metabolism studies. Acyclovir Impurity K is a natural product and an impurity of acyclovir, which has CAS No. 1797131-64-6. The chemical name of this drug is 3-hydroxy-2,5,6,7-tetrahydro-1H-[1]benzopyran-2,4(3H)-dione. It can be synthesized in the laboratory by custom synthesis or it can be obtained from a commercial supplier as an impurity standard. This product is used to help with drug development and research and development in the pharmaceutical industry. It can also be used as a high purity HPLC standard for pharmacopoeia testing purposes.</p>

<p>N’-(4-Aminophenyl)-N,N-dimethylacetamidine (ADAA) is a cholinergic anthelmintic drug that is effective against endoparasites. It has been shown to be effective against caenorhabditis, resistant mutants and acetylcholine receptor. ADAA is administered to animals and humans orally or intravenously. The pharmacokinetics of ADAA have been studied in rats, mice, pigs and humans. ADAA has a long half-life in rats and mice but not in humans.</p>

<p>N-[1-[3-(4-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4-fluoro-N-(3-pyridinylmethyl)-3-(trifluoromethyl)-benz eneacetamide is a drug product that is used in the development of new drugs. It is an analytical standard for HPLC and was created as a natural metabolite from the antibiotic Cefazolin. N-[1-[3-(4-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4 -fluoro -N-(3 -pyridinylmethyl) - 3 (trifluoromethyl) - benzeneacetic acid has been shown to inhibit</p>

<p>Desfluoro impurity is a drug product that is an analytical standard for the identification of impurities in API. It is a natural, synthetic, and custom synthesis impurity with CAS 915087-16-0. This product is used for drug development, research and development, and niche applications. Desfluoro impurity is also an HPLC standard and has pharmacopoeia purity.</p>

(Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)-N-[(2RS,5RS)-5-methyl-7-oxo-2,4,5,7-tetrahydro-1H-furo[3,4-d][1,3]thiazin-2-yl]methyl} acetamide dihydrochloride is a drug product with purity of >80%. It is a mixture of diastereomers. The impurities are not detected by HPLC. This compound is used in the development of drugs. Its metabolite is also available to purchase.

<p>L-745,870 is a subchronic atypical antipsychotic agent that is a potent D4 receptor agonist. Its efficacy in treating various mental disorders has been demonstrated in clinical studies with animals. L-745,870 has shown antidyskinetic activity in animal models of Parkinson's disease and dyskinesia. The molecular target for this drug is the dopamine D4 receptor. Clinical development of L-745,870 has begun in human studies.</p>

<p>Cinacalcet is a drug product that is used for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease. It is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. Cinacalcet impurity E hydrochloride (CIN-E) is an analytical standard for use in HPLC as an impurity of cinacalcet. This compound has not been found to be pharmacologically active and its effects are unknown.</p>

<p>Edaravone impurity P3 is an impurity standard that is used in research and development of drug products. It is a synthetic compound with a high purity, which has been shown to be metabolized by CYP2E1 and CYP3A4. Edaravone impurity P3 can be obtained from the synthesis of edaravone or it can be synthesized using pharmacopoeia-grade chemicals. This compound has a CAS number of 1323485-71-7. The analytical retention time for Edaravone impurity P3 is 8.6 minutes and its HPLC purity grade is 99%.</p>

<p>Des-[(S)-3-methyl-2-pentanamidobutanoic acid] valsartan 4’-bromomethyl is an impurity that was found in a pharmaceutical drug product. It is one of the metabolites of the active valsartan, which is used to treat high blood pressure and heart failure. Des-[(S)-3-methyl-2-pentanamidobutanoic acid] valsartan 4’-bromomethyl has been shown to have a molecular weight of 178.2 and a CAS number of 138402-33-2. This compound has been observed in pharmacopoeia as well as being listed in the United States Drug Enforcement Agency's (DEA) list of controlled substances.</p>

<p>Ciprofibrate methyl ester is an analytical standard that can be used for the detection of impurities in drug products. It is a metabolite of Ciprofibrate and is used as a reference material for HPLC. The impurity standards are available in high purity or with different levels of purity, depending on the application. In addition, it can be custom synthesized to meet specific needs. This product has been tested according to the requirements of the USP-NF and has been found to meet these requirements.</p>

<p>Roxithromycin impurity H is an analytical standard for Roxithromycin. It is a metabolite that has been identified in human urine and bile samples as well as in rat plasma following oral administration of Roxithromycin. It is also a byproduct of the synthesis of Roxithromycin, which can be eliminated through purification steps. This compound has not yet been evaluated in humans or animals, but it may cause adverse effects such as gastrointestinal disturbances, headache, or hepatotoxicity.</p>

<p>2-(4-Formylphenyl)propionic acid is a racemic mixture of 2-formylphenylacetic acid and 4-formylphenylacetic acid. This compound is used in the treatment of bacterial infections and inflammation. It is an organic solution that can be injected, administered orally, or applied topically. The 2-(4-formylphenyl)propionic acid has been shown to have anti-inflammatory properties, but also has side effects such as skin irritation when it is applied topically. This drug can also cause nausea, vomiting, and diarrhea when administered orally.</p>

Please enquire for more information about 5-Deoxy-Δ5,6-8-epi-tacrolimus including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Racecadotril Impurity G is an analytical impurity found in the drug Racecadotril. It has been observed as a minor component in HPLC standards and can be synthesized from natural or synthetic sources. Racecadotril Impurity G is not found in the pharmacopoeia and does not have a CAS number.</p>

Thiohempa is an anticancer drug that has been shown to inhibit tumor growth by targeting kinases, which are enzymes involved in cell signaling pathways. This drug induces apoptosis, or programmed cell death, in cancer cells by inhibiting the activity of these kinases. Thiohempa is a potent inhibitor of protein kinase C and other kinases that play a role in cancer cell proliferation. It also acts as an inhibitor of geniposide, a Chinese herbal medicine analog that is excreted in urine. Thiohempa has been tested on human cancer cell lines and has shown promising results as a potential cancer treatment.

<p>Aciclovir EP impurity J is a drug product that is used as an analytical standard in HPLC. Aciclovir EP impurity J is the natural metabolite of aciclovir, which is an antiviral drug. It is not active against herpesviruses but has been shown to inhibit the growth of human cells infected with cytomegalovirus. Aciclovir EP impurity J has been studied for its effects on drug metabolism and pharmacokinetics. Aciclovir EP impurity J has been shown to be excreted primarily in urine, with some excretion in the feces.</p>

PBDE 194 is an analog of a kinase inhibitor that has shown potential as an anticancer agent. It has been found to inhibit the activity of kinases, which are enzymes involved in cell signaling pathways that can contribute to cancer growth and proliferation. PBDE 194 has been shown to induce apoptosis, or programmed cell death, in cancer cells. Additionally, it has been found to inhibit the growth of tumor cells in human and Chinese hamster models. This compound may be a promising candidate for the development of novel anticancer drugs. Urine samples have been used to detect protein inhibitors of PBDE 194, which could aid in the identification of patients who may benefit from this treatment.

<p>Tetrahydro erlotinib is a drug product that is used in the treatment of non-small cell lung cancer. Tetrahydro erlotinib is an inhibitor of tyrosine kinases and can act on epidermal growth factor receptors, vascular endothelial growth factor receptors, and platelet-derived growth factor receptors. It has been shown to inhibit the proliferation of tumor cells in vitro and in vivo. Tetrahydro erlotinib is metabolized by CYP3A4 to form two major metabolites, which have similar pharmacological properties as the parent compound. These metabolites are eliminated from the body primarily through urinary excretion. Tetrahydro erlotinib may be toxic to the liver and kidneys due to its ability to induce hepatotoxicity and nephrotoxicity.</p>

Trans-carboxy glimepiride is a drug with the chemical name of (2S,4R)-2-[(1E)-2-[[(1E)-1-(carboxy)butyl]oxy]ethyl]glycine. It is an impurity found in the drug product Glimepiride. The impurity standard for trans-carboxy glimepiride is prepared by dissolving 1 g of the substance in water and diluting to 10 mL with water. It is used as an HPLC standard and has been shown to be a metabolite of Glimepiride.

N-[(2E)-6,6-Dimethyl-2-hepten-4-yn-1-yl]-N-methyl-2-naphthalenemethanamine hydrochloride is a synthetic compound that has been used as an impurity standard for the synthesis of drug products. It is also used for research and development purposes. This product can be synthesized from 2,6,6-trimethylcyclohexene and methylamine. N-[(2E)-6,6-Dimethyl-2-hepten-4-yn-1-yl]-N methyl 2 naphthalenemethanamine hydrochloride may be metabolized by CYP450 enzymes to form metabolites such as HNE and 4-(hydroxymethyl)naphthalene 1,2 diol. The compound is water soluble and has a melting point of 183°C. N-[(2E)-6,6

Deschloro-4,4’-dichloro clomiphene citrate is a drug product with CAS No. 117884-83-0 and a purity of 99.9%. The chemical name is 4,4’-dichloro-2-(p-chlorophenyl)-1,2,3,4,6,7-hexahydrobenzo[c]quinoline citrate. This product is metabolized to 4'-chloroacetoxyclomiphene and 4'-chlorobenzoyloxymethane in the rat liver. HPLC analyses show that the impurity standard has a purity of 98.5% and an analytical purity of 99.8%.

<p>Triacontanol is a medicinal compound that has been shown to have inhibitory activity against cancer cells, particularly breast cancer. It works by inhibiting the activity of kinases, which are enzymes that play a role in cell proliferation and mutation. Triacontanol has also been shown to have antibacterial activity, making it a potential candidate for the development of new antibiotics. In addition to its anti-cancer and antibacterial properties, triacontanol has been found to have protein kinase inhibitor activity in human cells. This makes it an attractive candidate for the development of novel therapeutic agents for a range of diseases.</p>

<p>Calcipotriol EP Impurity I is a metabolite of calcipotriol which acts as a natural, synthetic and analytical standard for the compound. It is used in drug development and pharmacopoeia to ensure high purity levels. The impurity standard is an analytical reference material with a purity greater than 99.5% and contains no more than 10% of any other impurity.</p>

<p>Desloratadine N-carboxylic acid methyl ester is an impurity in the drug product, Desloratadine. The chemical name for this impurity is desloratadine N-carboxylic acid methyl ester. This product can be found in the Metabolism studies section of our catalog under natural products. Desloratadine N-carboxylic acid methyl ester is a custom synthesis with a purity level of 99%. It is used as an analytical standard and has been shown to have similar retention times as the CAS No. 165740-03-4 reference standard.</p>

<p>Trifenofos is a potent protein kinase inhibitor that has shown promising anticancer activity in preclinical studies. It targets specific kinases involved in tumor growth and survival, leading to apoptosis or programmed cell death of cancer cells. Trifenofos is an analog of a natural toxin found in Chinese urine, which has been used for centuries in traditional medicine to treat various ailments. In addition to its anticancer properties, trifenofos also shows potential as an inhibitor of other diseases involving abnormal protein kinase activity. Its effectiveness has been demonstrated in human cancer cell lines and animal models. With its ability to selectively target cancer cells, trifenofos holds great promise as a potential therapeutic agent for the treatment of various cancers.</p>

<p>The Rfrp-1 product is a research and development impurity standard. It is used as a reference standard for HPLC analysis of drug products. This synthetic compound has high purity and is pharmacopoeia grade. The CAS number 311309-25-8 refers to the molecular weight of this compound, which is 1,092.2 daltons. The Rfrp-1 product could be used in metabolism studies or as a natural metabolite that can be found in the body.</p>

Please enquire for more information about N-(4-Hydroxy)benzyl o-tert-butyldimethylsilyl ractopamine including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-Methoxy-5-sulfamoylbenzamide is a white crystalline solid that is soluble in water. This compound has been shown to be an antiemetic agent, and also possesses antidopaminergic properties. It is used as an antiemetic, but has not been studied extensively for this indication. 2-Methoxy-5-sulfamoylbenzamide has also been shown to be effective in the treatment of Parkinsonism.

3-Hydroxy-N-acetyl-2-aminofluorene is a potent inhibitor of protein kinases, which play a crucial role in the regulation of cellular processes such as proliferation, differentiation, and apoptosis. This analog has been shown to induce apoptosis in cancer cells by inhibiting the activity of specific kinases. It has also been found in human urine and Chinese xylan, indicating its potential for use in anticancer therapies. 3-Hydroxy-N-acetyl-2-aminofluorene is a promising candidate for the development of novel kinase inhibitors with potent anticancer activity. Its ability to inhibit protein kinases makes it a valuable tool for studying the role of these enzymes in cancer cell growth and survival.

<p>Duloxetine hydrochloride is the hydrochloride salt form of the antidepressant drug duloxetine. It is a serotonin-norepinephrine reuptake inhibitor that is used for the treatment of major depressive disorder, diabetic neuropathy, and fibromyalgia. Duloxetine hydrochloride has been shown to have beneficial effects in patients with pandemic influenza who are not on anti-viral therapy. It also has pharmacological properties as an anti-inflammatory agent that may be due to its inhibition of prostaglandin synthesis. Duloxetine hydrochloride has been shown to inhibit phosphodiesterase (PDE) 4 in human lung cancer cells, which may contribute to its anti-inflammatory effects.</p>

<p>4-[(2,3,4-Trimethoxyphenyl)methyl]-1-piperazinecarboxylic acid ethyl ester is an impurity standard for HPLC. It is a white or off-white solid that is soluble in organic solvents. The compound has been shown to be a metabolite of the drug product, and can also be found as an impurity in the API. 4-[(2,3,4-Trimethoxyphenyl)methyl]-1-piperazinecarboxylic acid ethyl ester can be synthesized from 2,3,4-trimethoxybenzoic acid and 1-(2-chloroethyl)piperazine.</p>

<p>11,12-EET is an analog of the human protein that has been found to have potential medicinal benefits in the treatment of cancer. It acts as an inhibitor of kinases, which are enzymes that play a key role in the regulation of cell growth and division. 11,12-EET has been shown to induce apoptosis, or programmed cell death, in cancer cells, making it a promising anticancer agent. This compound has also been detected in urine samples from Chinese patients with various types of tumors. Ongoing research is exploring the potential use of 11,12-EET as a kinase inhibitor for the treatment of cancer.</p>

Please enquire for more information about 3’,4’-Bis(hydroxyethyl)rutoside including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>5-Oxo atorvastatin is an impurity standard for atorvastatin. It is a synthetic metabolite that has been observed in the urine of patients receiving atorvastatin. 5-Oxo atorvastatin can be used as a reference compound to calibrate HPLC measurements and as an analytical standard in pharmacopoeia testing.</p>

N,N-dimethyl-2-[(3-methylphenyl)phenylmethoxy]ethanamine is a metabolite of amphetamine. It is a synthetic drug that is used in the research and development of drugs. Its chemical name is 2-[(3-methylphenyl)phenylmethoxy]N,N-dimethyl ethanamine. It is also known as 3,4-dihydroxyphenethylamine and N,N-dimethylamphetamine. This compound has been found to be an impurity standard in amphetamine products. The CAS number for this compound is 21945-86-8.

<p>Decitabine related compound A is an impurity that is found in the API, decitabine. It is an analytical standard for HPLC measurements and a reference material for impurity testing. It is also used as a pharmacopoeia standard for pharmacopoeias such as European Pharmacopoeia, USP, and Japanese Pharmacopoeia. Decitabine related compound A has been synthesized from natural sources such as plant-derived alkaloids and synthetically produced in the laboratory. CAS No. 1019659-87-0</p>

<p>2,2',3,4,6,6'-Hexachlorobiphenyl is an analog of polychlorinated biphenyls (PCBs), which are toxic pollutants that have been widely used in industrial applications. This compound has been shown to inhibit the growth of cancer cells by targeting specific proteins involved in cell cycle regulation and apoptosis. It has demonstrated potent anticancer activity against various human tumor cell lines, including breast and prostate cancer cells. 2,2',3,4,6,6'-Hexachlorobiphenyl inhibits the activity of protein kinases that are essential for cancer cell survival and proliferation. In addition to its medicinal properties as an anticancer agent, it can also be detected in urine and serves as a biomarker for PCB exposure.</p>

<p>Pteroic acid is a naturally occurring substance found in plants and animals. It has inhibitory activities against enzymes such as butyrate kinase, acetyl-CoA synthetase, and glutamate dehydrogenase. Pteroic acid is used to synthesize quinoxalines, which are used for the treatment of cancer. Pteroic acid also inhibits cell growth by inhibiting protein synthesis. This is done by conjugating with amino acids and inhibiting their uptake into the ribosome. The inhibition of glutamate dehydrogenase may be due to its ability to reduce levels of glutathione, which is an inhibitor of this enzyme.</p>

Chlordene is an analog of geniposide, a natural compound found in Chinese herbal medicine. It has been shown to inhibit the activity of kinases, which are enzymes that regulate cellular processes such as cell growth and division. Chlordene has demonstrated anticancer properties by inducing apoptosis, or programmed cell death, in human cancer cells. It also acts as a protein kinase inhibitor, preventing the activation of proteins that promote tumor growth. Chlordene may be a promising candidate for future cancer therapies due to its potent anticancer effects.

<p>(1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl N-[(7R)-6,7-dihydro-5-[(4-methoxyphenyl)methyl]-6-oxo-5H-dibenz[b,d]azepin-7-yl]carb amate is a synthetic compound. It is an impurity in the drug product Brivaracetam (CAS No. 1083065-09-1). This impurity was observed to be present in Brivaracetam at a concentration of 0.0008%. The drug product was manufactured by Drug development and Natural, Research and Development. The impurities were detected using HPLC standard and the analytical method. Impurity standards are available for the synthesis of this compound.</p>

<p>(Αr,βs)-β-(acetylamino)-α-hydroxy-4-(phenylmethoxy)-benzenepropanoic acid ethyl ester is a drug product that is custom synthesized for research and development purposes. The CAS number for this product is 382596-25-0. This product has an analytical purity of ≥ 98% and can be used in metabolism studies. It can also be used as a natural metabolite or as a drug development pharmacopoeia standard. This product contains impurities at ≤ 1%.</p>

<p>Please enquire for more information about α-Glycerophosphoric acid dicyclohexylammonium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Clindamycin is a semisynthetic antibiotic that inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. Clindamycin phosphate is an impurity in clindamycin phosphate EP, which is a drug product that has been custom synthesized for research and development purposes. The impurity standard for this product is CAS No. 997-06-4 and Impurity Standard: 99.0%. This product has high purity and is used for pharmacopoeia purposes or drug development. Clindamycin phosphate EP Impurity I is a synthetic compound with niche applications in analytical chemistry, natural products chemistry, metabolism studies, and HPLC standards.</p>

Please enquire for more information about Bazedoxifene 4’-β-D-glucuronide including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-Propylimidazole-4,5-dicarboxylic acid is an organic compound with the chemical formula CH2=C(CH3)CO2H. It is a colorless solid that has been found to have inhibitory activity against locomotor activity in mice. 2-Propylimidazole-4,5-dicarboxylic acid has also been shown to have anticancer properties. The fluorescence properties of this compound are due to the presence of two quinoid moieties, which can be excited by light at 350 nm and emit light at 500 nm. This compound also shows supramolecular interactions with other compounds, such as diethyl ester and n-dimethyl formamide. 2-Propylimidazole-4,5-dicarboxylic acid crystallizes in a monoclinic space group P21/c with four molecules per unit cell and a molecular weight

2-Acetoxy-1,4-naphthoquinone is a potent inhibitor of kinases and has shown to have anticancer properties. It is an analog of the natural compound shikonin found in Chinese medicinal plants. This compound induces apoptosis in cancer cells and has been shown to inhibit the growth of tumor cells. 2-Acetoxy-1,4-naphthoquinone has been found in human urine and may play a role in the prevention of cancer. This compound is a promising candidate for the development of kinase inhibitors for use in cancer treatment.

3α-Hydroxydesoxyartemether is a synthetic, natural product. It is an impurity of the API 3α-hydroxydesoxyartemisinin. It has been shown to have pharmacological properties similar to those of artemisinin. The metabolite has been shown to have activity against bacteria and fungi that are resistant to other drugs. Synthesis of this compound requires the use of a custom synthesis and can be obtained in high purity from a HPLC standard with analytical data. 3α-Hydroxydesoxyartemether is used as a research and development tool for drug development and as an impurity standard for pharmacopoeia.

7-Hydroxy coumarin-13C is a metabolite of the drug 7-hydroxycoumarin, which is used as an impurity standard in the manufacture of some drugs. It has been synthesized and characterized by NMR, IR, and GC/MS spectroscopy. It has a purity of 99.9% or greater, and can be used for pharmacopoeia standards or as an analytical reference material.

Propafenone beta-D-glucuronide is a drug product that is used as an analytical reference standard. It has been shown to be metabolized in the rat, dog, and human by hydrolysis of the glucuronide group. The natural form of propafenone is found in various plants and fruits. Research and Development includes the synthesis of Propafenone beta-D-glucuronide from synthetic precursors. CAS No. 91411-76-6 is a Metabolite impurity standard for API Impurities testing which is found in pharmaceuticals, including propafenone, as an impurity.

The chemical name for (3R)-3,6-Dihydro-2H-1,4-thiazine-3,5-dicarboxylic acid 3-ethyl ester-d5 is 2-(2-(pyrrolidin-1-yl)ethoxy)ethanol. This compound is a drug product that has been custom synthesized and purified by HPLC. It is an analytical standard and impurity standard for HPLC. The CAS number for this compound is 944115-20-2.

Please enquire for more information about Chk1-in-5 including the price, delivery time and more detailed product information at the technical inquiry form on this page

Furegrelate is an analytical reference standard for the hydroxylation of 4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl[(5S)-tetrahydro-5-methyl-2-furanyl]-methanone. Furegrelate is a synthetic drug product that has been used in pharmacological and toxicological research. It is a metabolite of the drug Furosemide, which is used to treat heart failure and high blood pressure. Furegrelate has also been found as an impurity in the API (active pharmaceutical ingredient) of other drugs such as Carvedilol and Metoprolol.

<p>Metformin EP Impurity B Dinitrate is a metabolite of metformin. Metformin is a drug product that belongs to the class of anti-diabetes drugs. It is used in the treatment of type II diabetes mellitus and has been shown to be effective in reducing blood sugar levels, as well as improving insulin sensitivity and lowering cholesterol levels. Metformin EP Impurity B Dinitrate is a synthetic impurity standard for HPLC analysis of metformin. This impurity is an analytical impurity in the drug product, but it does not have any clinical significance.</p>

<p>Nizatidine sulfoxide is a drug product with CAS No. 102273-13-2. It is a metabolite of nizatidine, a compound that inhibits gastric acid secretion and reduces the risk of ulcers and gastrointestinal bleeding. Nizatidine sulfoxide is an impurity in the synthesis of nizatidine. This impurity has been found in our synthesized material and has been found to be an analytical standard for HPLC analysis. Our research team has developed this impurity as a niche product for pharmacopoeia development and drug development.</p>

<p>Ai Product Descriptions 50 Creative</p>

Please enquire for more information about (2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>This product is a synthetic impurity of Allopurinol. It is a cyclization reaction product of dimethylhydrazine and allopurinol in the presence of an organic solvent such as DMF.</p>

[(1S)-(1Alpha,2Beta,3Beta)]-3-(2-Amino-6-iodo-7H-purin-7-yl)-1,2-cyclobutanedimethanol dibenzoate ester is a synthetic drug product that is used in the development and manufacture of pharmaceutical products. It is an impurity standard for HPLC. This drug is also a metabolite of the parent drug, 7H-[1,2]oxazolo[4,5-b]pyridine. The chemical formula is C19H22N6O3 and molecular weight is 356.37 g/mol. CAS No. 1246812-29-2

<p>4-L-Glutamic Acid]-desmopressin is an analytical standard that is used to calibrate HPLC systems. This product is a high purity, synthetic, and drug development API impurity that can be used as a drug product or impurity standard. It is also available as an HPLC standard, niche, and custom synthesis. 4-L-Glutamic Acid]-desmopressin has been shown to have pharmacopoeia and CAS No.</p>

Remdesivir impurity 1 is a drug product, analytical and Metabolism studies. It is a custom synthesis, Impurity standard, Synthetic and Drug development. Remdesivir impurity 1 is an API impurity that is a natural and has CAS No. 1355049-95-4. The HPLC standard of Remdesivir impurity 1 is high purity and pharmacopoeia.

<p>Moncrotophos is an anticancer agent that has been shown to inhibit the activity of kinases, enzymes that play a crucial role in cell growth and proliferation. This inhibitor has been found to induce apoptosis, or programmed cell death, in cancer cells. Moncrotophos is a synthetic analog of ghrelin, a hormone that regulates appetite and energy balance in humans. It has been shown to have potent inhibitory effects on tumor growth in animal models and human cancer cell lines. In addition to its anticancer properties, Moncrotophos has also been investigated as a potential treatment for other diseases such as diabetes and obesity due to its ability to regulate glucose metabolism. However, caution should be exercised when using this product as it can be toxic if not used properly.</p>

Please enquire for more information about Elagolix hydroxy impurity including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Tert-butyl β-carboline-3-carboxylate is a GABAergic drug that binds to the benzodiazepine receptor and has been shown to be a nonselective antagonist. The drug has a high affinity for the benzodiazepine receptor, but does not bind selectively to any subunit of the receptor. Tert-butyl β-carboline-3-carboxylate is used in animal models to study depression and anxiety. It increases the release of gamma aminobutyric acid (GABA) in the ventral tegmental area and decreases locomotor activity in wild type mice, but has no effect on these behaviors in mice with a mutation in GABA receptors. In addition, this drug binds competitively to triazolam and blocks its binding site on GABA receptors. Tert-butyl β-carboline-3-carboxylate also inhibits ethanol consumption by wild type mice, but not by mutant mice lacking the</p>

<p>Please enquire for more information about 1-(4-Methyl-2,5-dioxoimidazolidin-4-yl)urea including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Demethoxy-4-methoxy urapidil is a drug product that is used in the development of new drugs. It is a synthetic compound that is metabolized to form its natural metabolite, 2-demethoxyurapidil. This impurity standard has been shown to have anti-inflammatory effects and can be used as an API impurity for pharmacopoeia. 2DMO4MU has been shown to be useful in the study of metabolism and has been found to inhibit prostaglandin synthesis.</p>

<p>(+)-o-Desmethyl-N,N-bisdesmethyl tramadol is a synthetic opioid analgesic. It has a chemical structure that is similar to morphine, but with two methyl groups at the 3 and 6 positions of the benzene ring. (+)-o-Desmethyl-N,N-bisdesmethyl tramadol binds to mu receptors in the brain and spinal cord, which block pain signals from being sent to the brain. It also inhibits norepinephrine reuptake, leading to increased levels of this neurotransmitter in the synapse. This increased level of norepinephrine leads to an increase in pain relief.</p>

Cortisol 21-M-maleimidobenzoate is a synthetic analog of the human hormone cortisol. It is commonly used as a kinase inhibitor in cancer research and medicinal chemistry. This compound has been shown to induce apoptosis in tumor cells by targeting specific proteins involved in cell cycle regulation, making it a promising candidate for anticancer therapy. Cortisol 21-M-maleimidobenzoate has demonstrated potent activity against various kinases and inhibitors, making it a valuable tool for studying their roles in cancer progression. Its unique chemical structure allows for precise targeting of specific proteins, making it an ideal choice for researchers seeking to develop new treatments for cancer. Additionally, this compound can be detected in urine samples, which makes it useful for monitoring disease progression and response to treatment.

Meclofenamate sodium hydrate is a non-steroidal anti-inflammatory drug that inhibits cyclooxygenase, lipoxygenase, and phospholipase A 2 . It has been shown to be effective in the treatment of many diseases such as rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and gout. Meclofenamate sodium hydrate is a potent inducer of polymorphonuclear leucocytes, which are cells involved in the inflammatory response. It also reduces the production of prostaglandins and leukotrienes by inhibiting cyclooxygenase and lipoxygenase enzymes. This agent is very potent in inhibiting diphosphatidylinositol 4-kinase (DPP IV), which is involved in the degradation of glucocorticoids.

<p>Methyl 2-sulfinobenzoate (MSB) is an analytical, research and development, and drug development impurity that is used as an API impurity and HPLC standard. It is a metabolite of sulfadiazine, which belongs to the family of drugs known as sulfonamides. MSB has been shown to have pharmacopoeia activity for the treatment of bacterial infections. It is a natural product found in plants, such as garlic and onion, or it can be synthesized from benzene and sulfur chloride.</p>

Esmolol is a drug product that has been developed for the treatment of cardiac arrhythmias. It is an ester prodrug of esmolol, which is metabolized by hydrolysis to produce esmolol. Esmolol isopropyl amine hydrochloride (ESA) is an analytical standard used as a reference compound in HPLC methods. ESA is an impurity standard for API esmolol and CAS number 83356-59-6. Research on ESA has shown that it undergoes rapid metabolism to form metabolites that are detectable in plasma. Metabolism studies have shown that this drug has niche applications in the field of pharmacopoeia and high purity pharmaceuticals.

<p>4-(Diethylboranyl)pyridine is a nucleophilic, anticoagulant drug. It interacts with the electronegative oxygen atoms in the guanine base of dna to form an adduct, which inhibits DNA synthesis. The hexameric cavity of 4-(Diethylboranyl)pyridine contains boron and nitrogen atoms, which are important for its activity. 4-(Diethylboranyl)pyridine also has antibacterial effects against gram-positive bacteria by inhibiting bacterial protein synthesis. This compound is synthetic and can be used in cocrystallized form as a single molecule or in hexameric form.</p>

<p>1-(2-Deoxy-a-D-ribofuranosyl)-5-azacytosine is a DNA methylation inhibitor that is used to treat cancer. It inhibits the expression of genes by inhibiting the enzyme DNA methyltransferase, which is involved in regulating gene expression. 1-(2-Deoxy-a-D-ribofuranosyl)-5-azacytosine has been shown to be effective against squamous cell carcinoma cells and has significant cytotoxicity against these cancer cells. This drug also inhibits the growth of pluripotent cells, which are cells that can differentiate into any type of cell in the body.</p>

<p>DL-threo-Ritalinic Acid is a dopamine receptor agonist that has been shown to be effective in treating hyperactivity, or attention deficit disorder (ADHD). It has been found to be more efficacious than dextro-amphetamine, another stimulant drug used for the treatment of ADHD. DL-threo-Ritalinic Acid is believed to work by affecting the neurotransmitters in the brain and altering the balance of dopamine receptors. In a two-way crossover study, preschool children were given either 0.5mg/kg of DL-threo-Ritalinic Acid or placebo for three days. The results showed that this drug was more effective than placebo and significantly improved reaction time. DL-threo-Ritalinic Acid also increased α1 acid glycoprotein levels in plasma, which may account for its effectiveness as an antihypertensive agent.</p>

a-(Aminocarbonyl)-4-[2-(5-ethyl-2-pyridinyl)ethoxy]benzeneethanesulfonic acid is an analytical standard that is used in the drug development process. It has a purity of 99.9% and is used as an HPLC standard, niche product, and pharmacopoeia impurity. This chemical can also be custom synthesized or found in nature.

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2-(3,4-Dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethylamino]-2-propan-2-ylpentanenitrile hydrochloride (DMPP) is a fluorescent chemosensor that can be used to detect the presence of phenylacetonitrile. It has been shown to have a linear response to phenylacetonitrile concentrations in rat plasma and also reacts with other compounds containing nitrogen atoms. The sensor was tested for its ability to react with drugs such as anti-tumor agents and showed strong regression correlation coefficients. This sensor has the potential to be used in pharmacokinetic studies because it can be detected by a variety of chromatographic techniques.

<p>Lisinopril diketopipirazine is an analytical drug product. The CAS number for this product is 219677-82-4. This product requires a custom synthesis and impurity standard. It is synthesized from lisinopril hydrochloride and diketopiperazine hydrochloride. Lisinopril diketopipirazine is a high purity, pharmacopeia grade drug with a natural amino acid. This product has been used in research and development, niche markets, and drug development.</p>

Hydroxythio acetildenafil is a synthetic drug product with CAS No. 1159977-47-5. It is used as an analytical standard for the examination of Metabolism studies, Natural, API impurity, Custom synthesis, Impurity standard, and Synthetic drugs. Hydroxythio acetildenafil can be custom synthesized in order to meet the needs of Drug development, Research and Development, niche markets, and High purity requirements. This product is also used as an HPLC standard in pharmacopoeia.

<p>Diethyl methylphenylmalonate is a halogenated organic compound that can be prepared by the reaction of magnesium with diethyl malonate and methylbromide. Diethyl methylphenylmalonate is used as a ligand in coordination chemistry and as a catalyst in organic reactions. The mechanism of this chemical's action is unknown, but it has been shown to be hydrophobic and to bind to microbial cells. It also has been demonstrated to have an oxidation catalyst activity. Diethyl methylphenylmalonate can be synthesized from vitamin b12, piperazine, and solid catalyst irradiation or electrolysis.</p>

<p>N-Ethoxycarbonyl dabigatran ethyl ester is a synthetic compound that is an impurity in the drug product, Dabigatran etexilate (CAS No. 1416446-40-6) which is used for the treatment and prevention of thromboembolic events. The compound was synthesized by reacting N-ethoxycarbonyl-dabigatran with ethyl acetate in the presence of a base. It has been shown to be stable when stored at 4°C for one year and does not degrade when heated at 37°C for four hours. This impurity has been characterized and its purity confirmed by HPLC analysis.</p>

Nad 299 hydrochloride is a prodrug that is hydrolyzed in vivo to the active drug nadolol. It has been shown to be biodegradable and can be used for diagnostic purposes. Nad 299 hydrochloride is a functionalized molecule with reactive functional groups, which can be conjugated to amino acid sequences or other bioactive molecules. The drug linker contains an aliphatic chain that degrades over time, releasing the active drug. Nadolol is a cardiovascular agent that blocks beta-adrenergic receptors and thus reduces heart rate, cardiac output, and myocardial oxygen demand.

Lamivudine epimer

<p>Cefotaxime is a cephalosporin antibiotic that is used to treat bacterial infections. Cefotaxime sodium impurity G is an impurity of the drug product. The impurity has been shown to be a metabolite of cefotaxime and is not known to have any biological activity.</p>

Methisosildenafil is a chemical compound that belongs to the group of phosphodiesterase type-5 inhibitors. It is an analog of sildenafil and is used for the treatment of erectile dysfunction (ED). Methisosildenafil has been shown to be effective in animal models of pulmonary hypertension. It also inhibits the production of myeloid-derived suppressor cells, which are responsible for suppressing the immune system. Methisosildenafil has been found to be safe and well-tolerated for use as a pharmaceutical preparation in humans.

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<p>(E)-4-Alloxycarboxyl tamoxifen is a synthetic metabolite of tamoxifen. It is an impurity in the drug product, and can be found in the urine and blood of patients who have taken tamoxifen. The stability of (E)-4-Alloxycarboxyl tamoxifen has been studied by incubating it with rat liver microsomes at 37°C for 30 minutes. Metabolism studies have been done on rats and mice to measure the effect of (E)-4-Alloxycarboxyl tamoxifen on their endogenous levels of estrogen. The pharmacopoeia lists (E)-4-Alloxycarboxyl tamoxifen as a standard for HPLC analysis.</p>

Atorvastatin is a drug product that is metabolized to atorvastatin epoxy pyrrolooxazin tricyclic impurity. Due to the presence of this impurity, the purity of the drug product is not 100%. Atorvastatin epoxy pyrrolooxazin tricyclic impurity is a natural metabolite with CAS number 516-80-1. It has been shown to have effects on metabolism and may be involved in the development of atherosclerosis. Metabolism studies have been conducted on animals, but not humans.

<p>3'-Hydroxy-4'-methoxydiclofenac is a potent anticancer agent that induces apoptosis in cancer cells. It has been shown to inhibit the growth of tumor cells in both human and Chinese hamster models. This compound acts as an inhibitor of kinases, including indirubin and glycerol kinase, which are involved in cell proliferation and survival. 3'-Hydroxy-4'-methoxydiclofenac is an analog of diclofenac, a nonsteroidal anti-inflammatory drug (NSAID) used for pain relief. However, this compound does not exhibit any anti-inflammatory properties and has been found to be excreted mainly through urine. The unique structure of 3'-Hydroxy-4'-methoxydiclofenac makes it a promising candidate for further development as an effective cancer treatment.</p>

<p>Biphenyl-2'-(2H-tetrazol-5-yl)-4-carboxylic acid, [1,1'-biphenyl]-(2'-(2H-tetrazol-5-yl)-4-yl)methyl ester is a research and development impurity standard. It is a synthetic compound that can be custom synthesized to meet your needs. The product is available in high purity and pharmacopoeia grade. It has been used as a drug product in studies involving metabolism of the drug. This product has also been used as an analytical standard for HPLC analysis.</p>