APIs pour la recherche et les impuretés
Sous-catégories appartenant à la catégorie "APIs pour la recherche et les impuretés"
- Acides Aminés et Dérivés(12.335 produits)
- Anthraquinones et Dérivés(405 produits)
- Dérivés du Benzimidazole et de l’Imidazole(10.451 produits)
- Dérivés des Benzodiazépines(334 produits)
- Glucides et Glycoconjugués(5.048 produits)
- Esters et Dérivés(42.251 produits)
- Acides Gras et Dérivés Lipidiques(32.417 produits)
- Flavonoïdes et Polyphénols(17.084 produits)
- Radicaux Libres et Agents Oxydants/Réducteurs(213 produits)
- Cétones et Dérivés(2.402 produits)
- Antibiotiques Naturels et Semi-Synthétiques(6.387 produits)
- Nitriles et Dérivés Cyano(3.068 produits)
- Nitrosamines et Dérivés(55 produits)
- Nucléosides et Nucléotides(3.484 produits)
- Phosphates et Phosphonates Organiques(1.201 produits)
- Sulfonates et Sulfates Organiques(10.435 produits)
- Composés Organométalliques(4.421 produits)
- Autres(6.307 produits)
- Peptides et Protéines(3.148 produits)
- Polymères et Dérivés(100 produits)
- Dérivés des Purines et Pyrimidines(8.948 produits)
- Dérivés de Quinazoline et de Quinoléine(66.045 produits)
- Quinones et Dérivés(24.363 produits)
- Sels et Dérivés d’API(80.490 produits)
- Stéroïdes et Dérivés(4.958 produits)
- Sulfamides et Dérivés(2.600 produits)
- Terpénoïdes et Dérivés(3.849 produits)
- Thiazolidinediones et Thiopyranes(2.754 produits)
- Composés β-Adrénergiques(231 produits)
57768 produits trouvés pour "APIs pour la recherche et les impuretés"
5-Desbromo, 5-chloro brimonidine
CAS :5-Desbromo, 5-chloro brimonidine is a drug product that is used as an analytical standard. It has been shown to be metabolized by CYP3A4 and CYP2D6 enzymes.
Formule :C11H10ClN5Degré de pureté :Min. 95%Masse moléculaire :247.68 g/molQuinidine methiodide
CAS :Quinidine is a drug that has been used in the treatment of cardiac arrhythmias and as an antiarrhythmic. It is an uncharged compound that can cross cell membranes by passive diffusion. Quinidine binds to the sodium ion channel, which is the pore through which sodium ions enter the cell, and causes it to close, thereby preventing them from entering the cell. This leads to decreased conductance of nerve impulses and a decrease in membrane potential. The effectiveness of quinidine is dependent on its concentration and on the duration of exposure to this drug.
Formule :C21H27IN2O2Degré de pureté :Min. 95%Masse moléculaire :466.4 g/molPhenothiazine S,S-dioxide
CAS :Phenothiazine S,S-dioxide is a fluorescent anion that can be used as a buffer. It has an absorption maximum at 514 nm in the visible region and a fluorescence emission maximum at 592 nm. Phenothiazine S,S-doxide blocks the emission of light from phosphor by absorbing the light and reemitting it at a longer wavelength. The luminescence intensity increases with increasing concentration of phenothiazine S,S-dioxide. This compound has been used to develop devices that detect anions in drinking water such as chloride ion. Phenothiazines are also known to have anti-inflammatory effects due to their ability to inhibit prostaglandin synthesis.
Formule :C12H9NO2SDegré de pureté :Min. 95%Masse moléculaire :231.27 g/molAmlodipine besilate impurity D
CAS :Amlodipine besilate impurity D is a diluent, additive, and stabilizer. It is used in the formulation of pharmaceuticals and other products to prevent particle agglomeration, maintain stability and provide uniformity. Amlodipine besilate impurity D is also used to manufacture bulk density stable pharmaceutical compositions that are suitable for hplc analysis. This product contains magnesium hydroxide as an impurity.
Formule :C20H23ClN2O5Degré de pureté :Min. 95%Masse moléculaire :406.86 g/molRef: 3D-IA63613
Produit arrêtéBenzathine ampicillin
CAS :Benzathine ampicillin is a penicillin antibiotic that belongs to the group of β-lactam antibiotics. It is used as an analytical reference standard in the pharmaceutical industry, and is also used as a high purity API impurity. Benzathine ampicillin has been shown to be metabolized by liver enzymes into penicillin G and 6-aminopenicillanic acid. The pharmacopoeia requires that benzathine ampicillin be at least 98% pure for its use in drug products.
Formule :C48H58N8O8S2Degré de pureté :Min. 95%Masse moléculaire :939.20 g/mol3,14-Dihydroxy 14β-estra-1,3,5(10)-trien-17-one
CAS :Produit contrôléPlease enquire for more information about 3,14-Dihydroxy 14β-estra-1,3,5(10)-trien-17-one including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C18H22O3Degré de pureté :Min. 95%Masse moléculaire :286.4 g/mol4,6-Dimethoxy-β-methyl-3-phenoxy ambrisentan
CAS :Produit contrôlé4,6-Dimethoxy-β-methyl-3-phenoxy ambrisentan is a synthetic drug with a high purity and pharmacopoeia. It belongs to the group of drugs called prostanoids, which are lipid molecules that act as hormones. 4,6-Dimethoxy-β-methyl-3-phenoxy ambrisentan is used in research and development for the treatment of pulmonary arterial hypertension. It is an impurity standard for HPLC analysis. This compound can be custom synthesized for drug product research and development. Metabolism studies have been conducted on this compound. The metabolites have been identified as 4,6-dimethoxy-(E)-2-[(E)-2-(4'-methylbenzylidene)ethenyl]-3-[(Z)-1-(4'-methylbenzylidene)ethenyl]ambrinol (M1), 4,6-dimethoxy-(E)-Formule :C22H22N2O6Degré de pureté :Min. 95%Masse moléculaire :410.4 g/molBrexpiprazole impurity 10
CAS :Brexpiprazole impurity 10 is a drug product that is used as an analytical reference standard for the quality control of brexpiprazole. This drug product is a synthetic substance with a high purity and is designed for use in HPLC analyses. This impurity can be used as a reference to identify other metabolites of brexpiprazole, such as 3-desacetyl-brexpiprazole, which are not necessarily identified by mass spectrometry. The CAS number for Brexpiprazole impurity 10 is 15116-41-3 and it has been assigned the IUPAC name 2-[2-[(2S)-2-[[(3S)-3-[4-(1,1-dimethylethyl)phenoxy]propyl]amino]-3-methylbutanoyl]-1H-indol-5-yl]acetic acid.
Formule :C16H15NO2Degré de pureté :Min. 95%Masse moléculaire :253.3 g/molN-Carboxylate-6-hydroxy melatonin ethyl ester
CAS :Please enquire for more information about N-Carboxylate-6-hydroxy melatonin ethyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C16H20N2O5Degré de pureté :Min. 95%Masse moléculaire :320.34 g/molPirtenidine
CAS :Pirtenidine is a potent and selective kinase inhibitor that has been shown to inhibit the activity of cyclin-dependent kinases. It has demonstrated promising results in preclinical studies as an anticancer agent, inducing apoptosis in cancer cells. Pirtenidine is an analog of protein kinase inhibitors, which have been used to treat various types of tumors. It has been found to be effective against human cancer cell lines and has shown significant tumor growth inhibition in animal models. Pirtenidine has also been reported to be a potent urine inhibitor of Chinese hamster ovary cells, making it a promising candidate for the treatment of urinary tract cancers.
Formule :C21H38N2Degré de pureté :Min. 95%Masse moléculaire :318.5 g/molMethyl mycophenolate impurity E
CAS :Methyl mycophenolate impurity E is a reactive, propargylamine-containing, monosodium salt with immunosuppressive properties. It is used in the treatment of cancer by inhibiting the production of white blood cells, which are needed to fight infection. Methyl mycophenolate impurity E has shown antitumor activity and can be used for the treatment of some types of cancer. It is metabolized in vivo to methyl mycophenolate and inhibits protein synthesis by alkylating DNA.
Formule :C18H22O6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :334.36 g/mol1-[2-[2-Hydroxy-3-[[2-hydroxy-3-[2-(3-phenylpropanoyl)phenoxy]propyl]-propylamino]propoxy]phenyl]-3-phenylpropan-1-one
CAS :Arbidol is a drug molecule that interacts with protease enzymes. It has been shown to inhibit human erythrocyte chymotrypsin, trypsin, and elastase. Arbidol is also able to inhibit the growth of bacteria such as Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. The molecular modelling of arbidol suggests that it binds to the active site of the enzyme by blocking hydrophobic pockets on the surface of the enzyme. The conformational change in the protease enzyme activates arbidol's binding site for an extended period of time. This prolonged interaction prevents substrate from binding to the catalytic site of the enzyme and inhibits its activity.
Formule :C39H45NO6Degré de pureté :Min. 95%Masse moléculaire :623.78 g/molDehydro nicardipine hydrochloride
CAS :Please enquire for more information about Dehydro nicardipine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C26H28ClN3O6Degré de pureté :Min. 95%Masse moléculaire :514 g/molN,5-Dibenzyl-5-hydroxy-indole-3-glyoxylamide
CAS :N,5-Dibenzyl-5-hydroxy-indole-3-glyoxylamide is a drug product that can be used as an analytical reference standard and an impurity standard. It is used in the development of drugs, including synthetic intermediates and metabolites. N,5-Dibenzyl-5-hydroxy-indole-3-glyoxylamide is a natural metabolite. It has been shown to have antihistamine activity and to inhibit prostaglandin synthesis.
Formule :C24H20N2O3Degré de pureté :Min. 95%Masse moléculaire :384.43 g/molRetinyl retinoate
CAS :Produit contrôléRetinyl retinoate is a synthetic retinoid that is chemically stable and has been shown to be effective in clinical studies. Retinyl retinoate is a lipophilic molecule with antioxidant properties, and it also has the ability to bind to hyaluronic acid and other natural compounds to maintain skin condition. This compound is synthesized by esterification of all-trans-retinoic acid with fatty acids, such as oleic acid or linoleic acid. The chemical structure of this compound can be determined by nuclear magnetic resonance spectroscopy.
Formule :C40H56O2Degré de pureté :Min. 95%Masse moléculaire :568.9 g/molVarenicline N-oxide
CAS :Varenicline N-oxide is a synthetic drug product. It is the metabolite of varenicline, which is used as an aid to smoking cessation. Varenicline N-oxide has shown anti-inflammatory properties in vitro and in vivo, and may be useful for treating inflammatory diseases. Varenicline N-oxide also has been shown to inhibit the production of nitric oxide in macrophages and prevent the release of tumor necrosis factor alpha by macrophages.
Formule :C13H13N3ODegré de pureté :Min. 95%Masse moléculaire :227.26 g/molRjr 2429 dihydrochloride
CAS :Rjr 2429 dihydrochloride is a tumor promoter that has been shown to induce tumor growth in tissues and in cell culture. It inhibits the proliferation of tumor cells by binding to retinol-binding protein, thereby preventing the uptake of vitamin A. Rjr 2429 dihydrochloride also induces the production of flavanones, which are known to be inhibitors of proliferative processes. This compound has been studied for its ability to prevent retinopathy and has been shown to inhibit light-induced photoreceptor degeneration in rats.
Formule :C12H18Cl2N2Degré de pureté :Min. 95%Masse moléculaire :261.19 g/molCp-66713 mesylate
CAS :Cp-66713 mesylate is a synthetic drug product with a molecular formula of C17H19NO2 and a molecular weight of 269.34. It has the following CAS number: 91896-58-1. The purity of this compound is >99% (HPLC).
Formule :C15H10ClN5Degré de pureté :Min. 95%Masse moléculaire :295.72 g/molIsopropyl (1S)-(+)-10-camphorsulfate
CAS :Isopropyl (1S)-(+)-10-camphorsulfate is an analytical standard that is used in the preparation of aqueous solutions with a purity of at least 99.5%. It can also be used as a reference material for the determination of impurities in drug products and API preparations. Isopropyl (1S)-(+)-10-camphorsulfate has been shown to inhibit bacterial growth, and may have anti-inflammatory properties. It has also been shown to bind to DNA and form adducts with guanine residues, which may lead to mutagenicity.
Formule :C13H22O4SDegré de pureté :Min. 95%Masse moléculaire :274.38 g/molDesisobutyl-N-butyl bortezomib
CAS :Desisobutyl-N-butyl bortezomib is a drug product that has been custom synthesized for the purpose of research and development. The synthetic compound is an impurity standard for the API Desisobutyyl-N-butyl bortezomib. This API is metabolized in both humans and rats, with metabolites being found in urine, feces, and exhaled air. The impurities in this drug product are a result of incomplete synthesis and are not of natural origin.
Formule :C19H25BN4O4Degré de pureté :Min. 95%Masse moléculaire :384.2 g/molDesmethyl dehydro lercanidipine
CAS :Desmethyl dehydro lercanidipine is a metabolite of lercanidipine, an antihypertensive agent. Lercanidipine is a dihydropyridine calcium channel blocker that inhibits the influx of calcium ions into cardiac muscle cells and vascular smooth muscle cells. The desmethyl form of lercanidipine has been shown to have anti-inflammatory effects in rats with experimental arthritis. It has also been shown to inhibit the production of inflammatory cytokines in lipopolysaccharide-stimulated human peripheral blood mononuclear cells.
Formule :C35H37N3O6Degré de pureté :Min. 95%Masse moléculaire :595.70 g/molRegadenoson Impurity 28
CAS :Regadenoson Impurity 28 is an analytical standard and research and development impurity. It is a high-purity, synthetic, drug product impurity that can be used as a reference material for HPLC. This drug impurity is also available in a custom synthesis service. Regadenoson Impurity 28 is an API impurity that can be used in the development of drugs. It has been shown to have pharmacopoeia purity standards and niche applications. Regadenoson Impurity 28 is metabolized by cytochrome P450 enzymes to form active metabolites that are not active against the beta-1 adrenergic receptor in rat heart cells, but are active against the alpha 1 adrenergic receptor in rat vascular smooth muscle cells.
Formule :C10H14N6O3Degré de pureté :Min. 95%Masse moléculaire :266.26 g/molCefdinir impurity E
CAS :Cefdinir impurity E is a research and development, impurity standard, custom synthesis, drug product, synthetic, high purity, pharmacopoeia, drug development and analytical standard. CAS No. 946573-41-7 is the metabolite of cefdinir. It is used to study metabolism of cefdinir in vitro and in vivo. HPLC standards are available for this compound.
Degré de pureté :Min. 95%Boc-3-hydroxy-1-adamantyl-glycine
CAS :Boc-3-hydroxy-1-adamantyl-glycine is a catalytic, nucleophilic, chiral amino acid that is used in the synthesis of oximes. Boc-3-hydroxy-1-adamantyl-glycine has been shown to be an effective substitute for hydroxylamine in reductive amination reactions and can be used to synthesize some pharmaceuticals, including saxagliptin. This compound is stable under standard conditions and can be easily synthesized. It is also a powerful nucleophile that reacts with electrophiles such as chloroformates and sulfonyl chlorides.
Formule :C17H27NO5Degré de pureté :Min. 95%Masse moléculaire :325.4 g/molL-745,870 Trihydrochloride
CAS :L-745,870 is a subchronic atypical antipsychotic agent that is a potent D4 receptor agonist. Its efficacy in treating various mental disorders has been demonstrated in clinical studies with animals. L-745,870 has shown antidyskinetic activity in animal models of Parkinson's disease and dyskinesia. The molecular target for this drug is the dopamine D4 receptor. Clinical development of L-745,870 has begun in human studies.
Formule :C18H22Cl4N4Degré de pureté :Min. 95%Masse moléculaire :436.2 g/molAnhydro galanthamine
CAS :Produit contrôléAnhydro galanthamine is a drug product that is custom synthesized to meet the needs of researchers. The purity of this compound can range from 99% to 99.99%. This molecule has been extensively studied and is found to be metabolized by CYP1A2, CYP3A4, and CYP2D6. Anhydro galanthamine also inhibits the synthesis of acetylcholine in the brain, which may lead to its use as a treatment for Alzheimer's disease.
Formule :C17H19NO2Degré de pureté :Min. 95%Masse moléculaire :269.34 g/mol3’-o-Desmethyl aliskiren hydrochloride
CAS :Please enquire for more information about 3’-o-Desmethyl aliskiren hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C29H51N3O6Degré de pureté :Min. 95%Masse moléculaire :537.7 g/mol1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]thio]-1H-benzi midazole
CAS :1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]thio]-1H-benzi midazole is a high purity analytical standard that is used to calibrate HPLC. It is found as an impurity in the drug product and as a metabolite. 1-[(3-Methyl-4-(2,2,2 -trifluoroethoxy) - 2 - pyridinyl) methyl] - 2 - [[[3 - methyl (4 ( 2 , 2 , 2 - trifluoroethoxy) - 2 pyridinyl) methyl] thio] - 1 H benzimidazole is the IUPAC name for this compound. This chemical has been synthesized
Formule :C25H22F6N4O2SDegré de pureté :Min. 95%Masse moléculaire :556.52 g/mol(E/Z)-It-603
CAS :Please enquire for more information about (E/Z)-It-603 including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C11H9BrN2O3SDegré de pureté :Min. 95%Masse moléculaire :329.17 g/molRef: 3D-SLA16890
Produit arrêtéVandetanib N-oxide
CAS :Vandetanib N-oxide is a drug product that is custom synthesized for research and development purposes. It has been shown to have high purity, analytical, and natural properties. Vandetanib N-oxide can be used as a metabolite or impurity standard in pharmacopoeias, such as the USP. The compound also has niche use in drug development and metabolism studies.
Formule :C22H24BrFN4O3Degré de pureté :Min. 95%Masse moléculaire :491.40 g/mol8-Benzyloxy-5-[(R)-2-bromo-1-(tertbutyldimethylsilyloxy)ethyl]-1H-quinolinone
CAS :8-Benzyloxy-5-[(R)-2-bromo-1-(tertbutyldimethylsilyloxy)ethyl]-1H-quinolinone is a drug product that is used as an analytical standard in metabolism studies. It has been shown to be a natural impurity in the API, and is found in the synthesis of a custom synthesis. 8-Benzyloxy-5-[(R)-2-bromo-1-(tertbutyldimethylsilyloxy)ethyl]-1H-quinolinone has been synthesized and characterized as an impurity standard for HPLC analysis. This substance has been used extensively in drug development and research as well as being a pharmacopoeia grade material.
Formule :C24H30BrNO3SiDegré de pureté :Min. 95%Masse moléculaire :488.5 g/mol[5-L-Aspartic Acid]-desmopressin
Desmopressin is a synthetic drug that is used to treat diabetes insipidus and bleeding in patients who are on anticoagulants. It is also used as a diagnostic agent to distinguish between central and nephrogenic diabetes insipidus. Desmopressin is a peptide hormone with amino acid sequence L-Asp-D-Phe-L-Arg-L-Phe. It is synthesized by the combination of two amino acids, L-Aspartic Acid and L-Phenylalanine, which are then linked together through an amide bond. The synthesis of desmopressin occurs in two steps: first, the coupling of amino acid L-Aspartic Acid with the peptide linkage (N-[3-(2'-aminoethyl) carbonyl]glycine) to form the intermediate N-[3-(2'-Aminoethyl) carbonyl]-L-Aspartic Acid; second
Degré de pureté :Min. 95%5-(4-Methoxyphenyl)-3-methyl-1-oxa-3-azaspiro[5.5]undecane
CAS :5-(4-Methoxyphenyl)-3-methyl-1-oxa-3-azaspiro[5.5]undecane is an analytical standard used in HPLC and GC. It can also be used as a research and development standard or impurity to aid in the identification of compounds with similar structures. 5-(4-Methoxyphenyl)-3-methyl-1-oxa-3-azaspiro[5.5]undecane has a purity of 99% and a melting point of 80°C. The CAS number for this compound is 93413-70-8, and it is available for custom synthesis, natural, or synthetic production.
Formule :C17H25NO2Degré de pureté :Min. 95%Masse moléculaire :275.39 g/mol4-Hydoxymethyl-5-methylimidazol
CAS :4-Hydroxymethyl-5-methylimidazol (HMMI) is a corrosion inhibitor that is used in the production of nanomaterials. It has been shown to be an effective treatment for wastewater containing hydrochloric acid and organic solvents. The reaction between HMMI and the acids in wastewater forms a complex that prevents the corrosion of metal surfaces. HMMI can be synthesized by reacting aesculus with formaldehyde in an organic solvent, such as acetone or chloroform, at room temperature. HMMI has also been shown to have antiviral potency and is used in skin care products, such as lotions and shampoos, due to its ability to penetrate the skin barrier. Magnetic resonance spectroscopy (MRS) was used to study the effect of HMMI on skin cells, while electrochemical methods were used to investigate how it inhibits viral activity.
Formule :C5H8N2ODegré de pureté :Min. 95%Masse moléculaire :112.13 g/molLinagliptin impurity E
CAS :Produit contrôléLinagliptin impurity E is a metabolite of the drug Linagliptin. It is an analytical reference material that is used to calibrate HPLC and GC-MS methods for quality control and purity assessment of Linagliptin. This impurity standard is also used for metabolism studies.
Formule :C25H28N8O2Degré de pureté :Min. 95%Masse moléculaire :472.54 g/molcis-Tadalafil
CAS :Cis-Tadalafil is a potent inhibitor of phosphodiesterase 5, which is used to treat erectile dysfunction (ED) and primary pulmonary hypertension (PPH). It works by increasing blood flow to the penis, allowing men with ED to achieve and maintain an erection. Cis-Tadalafil is also used to treat symptoms of prostatic hyperplasia (enlarged prostate) in men. This drug has been shown to be effective in treating PPH by reducing pulmonary arterial pressure and improving exercise capacity. Cis-Tadalafil belongs to the carboline class of drugs and is a phosphodiesterase 5 inhibitor that selectively inhibits cGMP-specific phosphodiesterase type 5 (PDE5). This drug has been shown to be highly effective in treating both ED and PPH with minimal side effects.
Formule :C22H19N3O4Degré de pureté :Min. 95%Couleur et forme :White/Off-White SolidMasse moléculaire :389.4 g/molRef: 3D-FT27987
Produit arrêtéTofacitinib dihydro impurity
CAS :Tofacitinib dihydro impurity is a research and development impurity standard for the synthesis of Tofacitinib. It is a custom synthesis with high purity, pharmacopoeia grade, and synthetic. This product is also used in drug development for metabolism studies and analytical applications.
Formule :C16H22N6ODegré de pureté :Min. 95%Masse moléculaire :314.39 g/molRef: 3D-QQC97235
Produit arrêté3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride
CAS :3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride is a versatile compound with various characteristics and applications. It has been found to have diverse effects on different biological processes. This compound has shown potential as an antimuscarinic agent, which means it can block the action of acetylcholine at muscarinic receptors in the body.
Formule :C19H25ClN2O2Degré de pureté :Min. 95%Masse moléculaire :348.9 g/molRocuronium Bromide EP Impurity F Bromide
CAS :Rocuronium Bromide EP Impurity F Bromide is an impurity found in Rocuronium Bromide EP. It is a natural component of the drug product, which is a synthetic drug. The metabolite of this impurity is also found in the natural product, although at much lower concentrations. This impurity has been shown to be present as an analytical impurity in the API and custom synthesis process. This impurity standard has been synthesized synthetically for use in drug development and research and development, as well as for use in HPLC standards.Formule :C34H55N2O4·BrDegré de pureté :Min. 95%Masse moléculaire :635.72 g/molRef: 3D-IR178405
Produit arrêtéSimvastatin acid
CAS :Simvastatin acid is the active form of simvastatin, a drug used to lower blood cholesterol levels. Simvastatin acid inhibits HMG-CoA reductase, the enzyme that converts HMG-CoA to mevalonate. This conversion is a rate-limiting step in the synthesis of cholesterol and other lipids. Simvastatin acid binds to polymerase chain and drug transporter proteins, which leads to cell lysis. The concentration–time curve for simvastatin acid is linear and the half-life is approximately 12 hours. When simvastatin acid is administered with drugs that are potent inducers of CYP3A4 or UGT1A1 enzymes, there may be an increased risk for drug interactions. Simvastatin acid has shown no significant human pharmacokinetic interactions with food or grapefruit juice at doses up to 200 mg/day. There are limited data on the pharmacokinetics of simvastatin
Formule :C25H40O6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :436.58 g/molIvermectin impurity I
CAS :Ivermectin impurity I is an analytical standard that is used for pharmacopoeia and custom synthesis. It is a natural metabolite of the drug Ivermectin, which has been shown to have anti-inflammatory properties in mice. Ivermectin impurity I binds to nicotinic acetylcholine receptors, leading to muscle paralysis and death. This compound is found in high purity for research and development purposes.
Formule :C48H74O14Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :875.09 g/molN-Desacetyl thiocolchicoside
CAS :N-Desacetyl thiocolchicoside is a white crystalline powder that is soluble in water, methanol and acetone. It has a molecular weight of 320.2 and an empirical formula of C6H14O5. N-Desacetyl thiocolchicoside is used as an analytical standard for HPLC analysis, as a Research and Development (R&D) material for drug development, and as an impurity standard for the manufacture of pharmaceutical products. This compound has been shown to be a metabolite of thiocolchicoside and structurally similar to the drug product chitinase.
Formule :C25H31NO9SDegré de pureté :Min. 95%Masse moléculaire :521.58 g/molRoflumilast Impurity A
CAS :Roflumilast impurity A is a metabolite of roflumilast. It is a drug product that is used as an analytical standard for the determination of roflumilast in HPLC analysis. Roflumilast impurity A is not natural and is synthetic. It has been shown to be a substrate for CYP1A2, CYP2C8, CYP2C9, and CYP3A4 enzymes. Studies have shown that it may be involved in the metabolism of roflumilast through hydroxylation and deamination.
Formule :C16H14Cl2N2O3Degré de pureté :Min. 95%Masse moléculaire :353.2 g/molRef: 3D-IR168438
Produit arrêtéLinagliptin impurity G
CAS :Linagliptin impurity G is an impurity in the drug product Linagliptin. It is a natural substance and its CAS number is 668270-11-9. Impurity G can be synthesized from L-phenylalanine and cyclohexane carboxaldehyde in a two step process. The first step involves the reaction of L-phenylalanine with cyclohexane carboxaldehyde to yield methylcyclohexanecarboxylate, which then undergoes hydrolysis to give phenylcyclohexanol. In the second step, phenylcyclohexanol reacts with hydrochloric acid to produce phenylcyclohexanone, which is then oxidized with hydrogen peroxide to yield impurity G. Impurity G can also be found in the pharmacopoeia as a high purity HPLC standard for linagliptin.
Formule :C25H28N8O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :472.54 g/molRef: 3D-FA146003
Produit arrêtéSacubitril Impurity 2
CAS :Sacubitril Impurity 2 is a drug product that is an analytical impurity in Sacubitril. This impurity can be found in Sacubitril as a result of natural processes or as an API impurity during the synthesis process. Sacubitril Impurity 2 has been shown to have activity in Metabolism studies, Natural, and Custom synthesis. It has been shown to be a Synthetic impurity standard and HPLC standard. Sacubitril Impurity 2 is used for research and development purposes for the drug development industry, specifically for the niche market. It is also used as an analytical standard for pharmacopoeia methods.
Formule :C24H27NO4Degré de pureté :Min. 95%Masse moléculaire :393.48 g/molRef: 3D-IS181152
Produit arrêtéN-Benzyl albuterol
CAS :N-Benzyl albuterol is a drug product that is custom synthesized to be of high purity with an analytical standard. It is used in research and development, pharmaceutical development, and as a pharmacopoeia or analytical standard. N-Benzyl albuterol has been found to be a metabolite of the drug product Albuterol Sulfate. It is also used in metabolism studies and natural product research. The CAS number for this compound is 24085-03-8.
Formule :C20H27NO3Degré de pureté :Min. 95%Masse moléculaire :329.4 g/molTerbinafine dihydrochloride
CAS :Terbinafine is a drug used in the treatment of onychomycosis, tinea versicolor and dandruff. It belongs to the group of medicines known as antifungals and inhibits the growth of fungi by inhibiting their ability to make proteins. Terbinafine dihydrochloride is a form of terbinafine that is more soluble in water than terbinafine hydrochloride and can be used as a lubricant. Terbinafine hydrochloride is an industrial product that is used as a disintegrant in tablets and capsules.
Formule :C36H40N2Degré de pureté :Min. 95%Masse moléculaire :500.7 g/molN-Nitroso dorzolamide
N-Nitroso dorzolamide is a chemical compound used as an intermediate in the synthesis of dorzolamide, a carbonic anhydrase inhibitor used in the treatment of glaucoma and ocular hypertension.
Formule :C10H15N3O5S3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :353.44 g/molDicyclopropylamine hydrochloride
CAS :Dicyclopropylamine hydrochloride is a tyrosine kinase inhibitor that blocks the activity of jak2. It is an innovative molecule with the potential to be used in cancer treatment. Dicyclopropylamine hydrochloride has been shown to inhibit activation of tyrosine kinases, which are involved in cell signaling and proliferation. Dicyclopropylamine hydrochloride also has anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. This drug is not expected to have any toxicity or side effects because it can be easily metabolized by the liver.br>br> Dicyclopropylamine hydrochloride is a white solid with a melting point of 175°C. It has no detectable odor, and it is soluble in water and ethanol. The impurities found in this compound include myristic acid and amines, which can cause inflammatory diseases.br>br> D
Formule :C6H11N•HClDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :133.62 g/molCiprofloxacin ep impurity C
CAS :Ciprofloxacin ep impurity C is a synthetic compound. It is used as a research and development standard in the synthesis of ciprofloxacin. The purity of this compound is high, and it has been tested for metabolism studies. This impurity can be detected by HPLC using an analytical method with a natural reference substance. This impurity has not been evaluated for pharmacopoeia or CAS number.
Formule :C15H16FN3O3Degré de pureté :Min. 95%Masse moléculaire :305.30 g/molAcarbose Impurity E
CAS :Acarbose Impurity E is an impurity found in acarbose. It is a natural, API impurity and is a synthetic impurity standard. Acarbose Impurity E has been used in drug development research and development, as well as in the HPLC analysis of acarbose to generate a pharmacopoeia-grade purity standard.
Degré de pureté :Min. 95%Pramipexole EP Impurity C
CAS :Pramipexole EP Impurity C is a synthetic impurity that is used as an impurity standard in the manufacture of Pramipexole EP. It is also used as a research and development tool for drug product, custom synthesis, CAS No. 1973461-14-1, and analytical studies. This compound has been shown to be a metabolite of Pramipexole EP and may have pharmacological properties. Pramipexole EP Impurity C has been found to inhibit the growth of certain bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA) isolates.
Formule :C20H32N6S2Degré de pureté :Min. 95%Ref: 3D-FP165425
Produit arrêté2-(2-Amino-5-bromobenzoyl)pyridine
CAS :2-(2-Amino-5-bromobenzoyl)pyridine (2ABBP) is a chemical compound with the molecular formula C10H7BrN3. It is a glucuronide conjugate of 2-amino-5-bromobenzoic acid and has been used as an immunological reagent in the form of a monoclonal antibody. 2ABBP binds to dryopteris, which is a plant species that contains polyphenols called pteridines. 2ABBP has been shown to have anti-inflammatory properties in rat liver microsomes and cell culture experiments. The mechanism of action may involve inhibition of cyclooxygenase enzymes, which are involved in prostaglandin synthesis. 2ABBP also binds to human serum albumin and chaperones, proteins that bind other proteins or small molecules. The biological activity of 2ABBP may be due to its ability to form coval
Formule :C12H9BrN2ODegré de pureté :Min. 95%Masse moléculaire :277.12 g/molRef: 3D-IA17613
Produit arrêtéPiperacilloic acid
CAS :Piperacilloic acid is a synthetic compound that exhibits antibacterial activity. It has been shown to be effective against human pathogens, including urothelial carcinoma and human serum. Piperacilloic acid binds to the amino acids lysine and arginine in bacterial proteins and inhibits protein synthesis by inhibiting the function of enzymes that require these amino acids for their activity. The potency of piperacillin is low, but it is activated by hydrolysis in the acidic environment of the stomach or intestinal tract. Piperacilloic acid also has potential as a contraceptive agent because it may inhibit transcriptional regulation of genes that are involved in sperm production.
Formule :C23H29N5O8SDegré de pureté :(Elemental Analysis) Min. 90 Area-%Couleur et forme :PowderMasse moléculaire :535.57 g/molRef: 3D-FP27061
Produit arrêtéDesfluoro ezetimibe
CAS :Desfluoro ezetimibe is a synthetic cholesterol-lowering drug that inhibits intestinal cholesterol absorption. It is chemically synthesized, and the process includes the introduction of fluorine at the 3-position of the C-ring. Desfluoro ezetimibe is not metabolized in humans, but it may be subject to oxidative degradation. The product is also subject to oxidation by light and air, which may result in formation of impurities. The drug substance has been validated as well as its isomers and efficiencies in mass spectrometry detection.
Formule :C24H22FNO3Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :391.43 g/molRef: 3D-FD21193
Produit arrêtéOxacyclohexane open ring tacrolimus
CAS :Please enquire for more information about Oxacyclohexane open ring tacrolimus including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C44H71NO13Degré de pureté :Min. 95%Masse moléculaire :822.04 g/molN-Hydroxymethyl Sumatriptan
CAS :N-Hydroxymethyl Sumatriptan is an analytical standard and a research and development impurity. It is also used as an API impurity in drug product manufacturing. N-Hydroxymethyl Sumatriptan can be synthesized by reacting the parent drug with hydroxyl radicals, which is a process that yields no side products. N-Hydroxymethyl Sumatriptan can be found in the following pharmacopoeia: United States Pharmacopoeia (USP) 11>, European Pharmacopoeia (EP), Japanese Pharmacopoeia (JP)13>, British Pharmacopoeia (BP), and Chinese Pharmacopiae (CPC).
Formule :C15H23N3O3SDegré de pureté :Min. 95%Masse moléculaire :325.43 g/mol(4-Chlorophenyl)diphenylmethanol
CAS :Please enquire for more information about (4-Chlorophenyl)diphenylmethanol including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C19H15ClODegré de pureté :Min. 95%Masse moléculaire :294.8 g/molEmpagliflozin S-furanose
CAS :Empagliflozin S-furanose is a Custom synthesis drug product. It is an analytical standard with CAS No. 1620758-32-8, and it is used in research and development of new drugs. Empagliflozin S-furanose has been found to be a metabolite of empagliflozin, a drug that is used to treat type 2 diabetes mellitus. It is also used as an impurity standard for HPLC analysis of empagliflozin because it does not have any biological activity.
Formule :C23H27ClO7Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :450.91 g/mol(S)-Rabeprazole sodium
CAS :(S)-Rabeprazole sodium is an anticancer drug that acts as a kinase inhibitor. It is an analog of Rabeprazole and has been shown to inhibit the growth of cancer cells in vitro and in vivo. (S)-Rabeprazole sodium inhibits the activity of kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. (S)-Rabeprazole sodium has been tested against various types of cancer, including Chinese hamster ovary cells and tumor xenografts in mice. It has also been shown to inhibit elastin degradation, which is important for preventing metastasis of cancer cells. (S)-Rabeprazole sodium may be a promising candidate for the development of new anticancer drugs that target specific kinases and proteins involved in cancer cell growth and survival.
Formule :C18H21N3O3S•NaDegré de pureté :Min. 95%Masse moléculaire :382.43 g/mol(3S,4R)-Tofacitinib
CAS :(3S,4R)-Tofacitinib is a rhombic and paramagnetic compound with a Curie point of approximately 10.6°C. It is soluble in nonpolar solvents such as benzene and toluene. (3S,4R)-Tofacitinib has been shown to have magnetic properties that are dependent on the temperature and the frequency of the applied magnetic field. The paramagnetic resonance spectra were observed at 18°C and 32°C, while the paramagnetic resonance spectrum was observed at -2°C. The octahedral interactions are likely due to the presence of six different types of iron ions in the crystal structure.
Formule :C16H20N6ODegré de pureté :Min. 95%Masse moléculaire :312.37 g/molRef: 3D-STB57848
Produit arrêtéChlorthalidone impurity E
CAS :Chlorthalidone impurity E is an analytical standard for the HPLC analysis of chlorthalidone in pharmaceutical drug products and is a metabolite of chlorthalidone. Chlorthalidone impurity E is an API impurity that can be found in the synthesis of chlorthalidone, and it has been detected as a minor component in certain drug products. It is important to have an accurate specification for this compound, since it can affect the pharmacological properties of the drug product. The purity level of this compound must be at least 98% or greater to ensure that there are no contaminants present. This compound is also a metabolite of chlorthalidone and is used as a pharmacopoeia reference substance for testing equipment calibration.END>
Formule :C14H11ClN2O3SDegré de pureté :Min. 95%Masse moléculaire :322.77 g/molTriethylene glycol flufenamate
CAS :Etofenamate impurity
Formule :C20H22F3NO5Degré de pureté :Min. 95%Couleur et forme :Clear LiquidMasse moléculaire :413.39 g/molD-6-Cyano-6-norlysergic acid methyl ester
CAS :Please enquire for more information about D-6-Cyano-6-norlysergic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C17H15N3O2Degré de pureté :Min. 95%Masse moléculaire :293.32 g/molAtorvastatin calcium trihydrate EP Impurity G
CAS :Atorvastatin is a drug that belongs to the class of statins. It is used for the treatment of high cholesterol levels and other related diseases, such as cardiovascular disease. Atorvastatin calcium trihydrate EP Impurity G is an impurity that may be present in atorvastatin calcium trihydrate. This compound has not been found to have any pharmacological activity.
Formule :C34H37FN2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :572.67 g/molRef: 3D-IA182820
Produit arrêtéGS 441524 triphosphate
CAS :Triphosphorylated form of an antiviral nucleoside analog with activity against zoonotic feline infectious peritonitis virus (FIPV) and severe acute respiratory syndrome (SARS) virus from Coronaviridae family. The compound is the biologically active form of the GS 441524 prodrug and being triphosphorylated, it competes with natural nucleoside triphosphates in cells and interferes with viral RNA synthesis. Made to order.
Formule :C12H12N5O13P3·4NaDegré de pureté :(31P-Nmr) Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :531.20 g/mol
