APIs pour la recherche et les impuretés

Fonofos is a potent inhibitor that has been shown to induce apoptosis in Chinese hamster ovary cells. It is also known to inhibit chitin kinase, a protein that plays an important role in the biosynthesis of chitin, which is essential for the formation of cell walls in fungi and insects. Fonofos has medicinal properties and has been studied as a potential anticancer agent due to its ability to inhibit tumor growth. In vitro studies have shown that Fonofos can inhibit the growth of human cancer cells by inhibiting heparin-binding proteins. Additionally, it has been found to have inhibitory effects on several other enzymes involved in cancer development and progression. Although not approved for use in humans, Fonofos may hold promise as a therapeutic agent for the treatment of certain cancers.

(-)-Bornyl ferulate is a natural compound, specifically a type of ferulic acid ester, which is a secondary metabolite found in certain plants. Its source is primarily the essential oils and resins of various coniferous species, where it contributes to the plant's defense mechanisms. The mode of action of (-)-Bornyl ferulate involves its ability to scavenge free radicals, thus exhibiting antioxidant activity. It also modulates inflammatory pathways, suggesting possible anti-inflammatory effects.

o-Desmethyl venlafaxine N-dimer is a metabolite of venlafaxine that has been identified in human plasma. It is a white to off-white crystalline powder with a melting point of about 175°C. The purity of the product is more than 98%. It is soluble in methanol and ethanol, but insoluble in water. The o-desmethyl venlafaxine N-dimer was developed as an analytical reference standard for use in HPLC analysis of venlafaxine and its metabolites and impurities.

N-Formyl leurosine is an inhibitor of fatty acid synthesis. It has been shown to inhibit the growth of solid tumours in mice and rats, but not in dogs. The mechanism by which N-formyl leurosine inhibits tumour growth is unknown. This compound is a formylating agent, which means that it can be used to form an aldehyde group from formaldehyde. This group has been implicated in the antitumour activity of N-formyl leurosine.

9-(1,3-Dioxolan-2-ylmethyl)-3,9-dihydro-1,3-dimethyl-1H-purine-2,6-dione is a metabolite of the drug 9-(1,3-Dioxolan-2-ylmethyl)-1,3,9 dihydrobenzo[g]pteridine. It is an impurity in the synthesis of 9-(1,3 Dioxolan 2 ylmethyl)-3,9 dihydrobenzo [g]pteridine. The purity of this compound is > 99%, with a melting point range of 233 to 235 °C and a molecular weight of 244.24 g/mol. It is soluble in methanol and acetonitrile. This compound has been characterized by IR spectroscopy (ATR), 1H NMR (400 MHz) spectroscopy (CDCl 3 ), and mass spectrometry (HRMS

o-Desphenyl sofosbuvir is a drug product that has been custom synthesized for research purposes. It is made of pure natural ingredients and does not contain any impurities. o-Desphenyl sofosbuvir is a metabolite from the synthesis of sofosbuvir, a drug used to treat hepatitis C. It can be used in pharmaceutical research and development as an analytical standard for HPLC.

(E,Z)-Epalrestat methyl ester is a drug product that is custom-synthesized for research and development purposes. It is a natural metabolite of (E,Z)-epalrestat acid. The chemical name for this compound is 3-[(2-chlorophenyl)methyl]-N-(1H-indol-3-ylmethylene)malonamide. The molecular weight of this compound is 284.87 g/mol and it has an empirical formula of C24H27ClN2O2. It has been found to inhibit the activity of phosphodiesterase (PDE), which plays a role in the breakdown of cyclic nucleotides such as cAMP and cGMP. This product has high purity and analytical data that can be used for metabolism studies or clinical trials.