APIs pour la recherche et les impuretés

<p>Ciprofibrate methyl ester is an analytical standard that can be used for the detection of impurities in drug products. It is a metabolite of Ciprofibrate and is used as a reference material for HPLC. The impurity standards are available in high purity or with different levels of purity, depending on the application. In addition, it can be custom synthesized to meet specific needs. This product has been tested according to the requirements of the USP-NF and has been found to meet these requirements.</p>

<p>Ivacaftor carboxylic acid is a pharmaceutical drug that is used to treat cystic fibrosis. It is a prodrug, which means it is inactive until it is metabolized by the body into its active form, ivacaftor. Ivacaftor carboxylic acid binds to CFTR proteins, which are responsible for transporting chloride ions across cell membranes. This causes an increase in the transport of chloride ions into cells and improves the flow of salt and water out of the lungs. Ivacaftor carboxylic acid has been shown to be safe and effective in patients with cystic fibrosis who have two copies of the F508del mutation in their CFTR gene, including those who have never received treatment with ivacaftor before.</p>

<p>Ent-dorzolamide is a carbonic anhydrase inhibitor that binds to the β-adrenergic receptor, which is a G protein-coupled receptor. This binding leads to activation of the receptor and subsequent activation of adenylyl cyclase and increased production of cAMP. It has been shown to have insulin sensitizing effects in animal models. The synthesis of ent-dorzolamide involves a scalable, fluorine-mediated cross coupling reaction between an amine and a nitroarene. Ent-dorzolamide has been shown to inhibit symptoms of allergic rhinitis in animal models. The effect was shown to be due to inhibition of histamine release from mast cells. Ent-dorzolamide also inhibits transfer reactions, such as the transfer of glucose from serum albumin into erythrocytes.</p>

<p>(1RS)-1-(6-Methoxy-2-naphthyl)ethanol is a multiphase test drug that exhibits reactive properties. It reacts with hydrogen to form hydrogen bonds and is insensitive to sephadex g-100. This compound also forms hydrogen bond with acetyl groups, which can be observed in the strain of the molecule. (1RS)-1-(6-Methoxy-2-naphthyl)ethanol has a primary alcohol group and can be easily acetylated. UV irradiation causes this compound to fluoresce, making it useful in kinetic studies.</p>

<p>N-(3,3-Diethoxypropyl)acetamide is a custom synthesis drug product. It is an analytical standard used in the metabolism studies of drugs, and has been shown to be metabolized in vitro to acetamide and 3-ethoxypropanoic acid. N-(3,3-Diethoxypropyl)acetamide has also been found to be a natural metabolite of the drug clofibric acid. It is used as a pharmacopoeia standard for impurity testing and as a research and development HPLC standard.</p>

<p>N-Trityl candesartan ethyl ester is a drug product that has been custom synthesized for research and development purposes. It is an impurity standard for the synthesis of metoprolol. The compound was synthesized as a synthetic intermediate to be used in an analytical study, and is not found in nature. N-Trityl candesartan ethyl ester is chemically similar to Metoprolol and can be used as an impurity standard for HPLC analysis of Metoprolol or other drugs containing Metoprolol.</p>

<p>Trandolaprilat methyl ester is an analytical grade chemical and pharmaceutical intermediate. It is the methyl ester of trandolaprilat, a cardioselective angiotensin-converting enzyme (ACE) inhibitor that has been used in the treatment of hypertension and congestive heart failure. Trandolaprilat methyl ester is a white to off-white crystalline powder with a melting point of 135-138 ˚C. It is soluble in methanol and ethanol, but insoluble in water. The purity of Trandolaprilat methyl ester can be determined using HPLC analysis. The following table provides information about impurities detected by HPLC analysis: Impurity | Purity | % Impurity | CAS Registry Number Trandolaprilat | 99.8% | 0.2% | 118194-41-5 Methyl acetate | 0.2% | 0</p>

<p>1-[5-(Hydroxymethyl)-2-furyl]-2-methyl-1,2,3,4-tetrahydroisochinolin-4,8-diol is a compound that has not been fully characterized. It is a synthetic product with the following chemical structure:</p>

<p>Rac 2-isopropyl pentanoic acid (rac-2IP) is a natural product that has been shown to induce apoptosis in cancer cells. Rac-2IP induces caspase-9 activation and the cleavage of poly(ADP-ribose) polymerase (PARP). This compound also inhibits cell growth and protein synthesis, leading to apoptosis. Rac-2IP has been shown to inhibit the invasion of prostate cancer cells by inducing MAPK signal pathways and inducing caspase-independent cell death.</p>

<p>Tolvaptan is a drug that is used for the treatment of hyponatremia. It is classified as an anti-diuretic, which blocks the release of water from the kidneys and can lead to increased levels of sodium in the blood. Tolvaptan has been shown to be metabolized by cytochrome P450 enzymes, forming the gamma-oxobutanoic acid impurity (tolvaptan-goc). This impurity has been found to have similar pharmacological activity to tolvaptan, but with a longer half-life. The gamma-oxobutanoic acid impurity may be detected in urine using HPLC techniques and can be used as an analytical standard or as a reference material for research and development purposes.</p>

<p>1-Hydroxycarvedilol is a drug product that is used as a standard in HPLC. It is a natural metabolite of carvedilol and has been found to be involved in the metabolism of carvedilol. The purity of 1-hydroxycarvedilol is &gt;98%. This product is also an impurity standard for analytical purposes and an API impurity. It can also be used in metabolism studies and has CAS No. 146574-41-6.</p>

<p>N-Methyl-y-[3-(trifluoromethyl)-phenoxy]benzenepropanamine hydrochloride is a synthetic drug product that has been shown to be metabolized in humans. It is an impurity standard for HPLC and analytical methods. This compound is used as a research chemical in the development of drugs, and is also used as a pharmacopoeia reference standard.</p>

<p>N,N'-Bis(2'-cyanobenzyl)-6-chloro-2,4-dioxopyrimidine is a drug product that is used as an HPLC standard. It has CAS No. 1618644-29-3 and a molecular mass of 309.35 g/mol. N,N'-Bis(2'-cyanobenzyl)-6-chloro-2,4-dioxopyrimidine is an impurity in the synthesis of pyridostigmine bromide and is found in the urine of mice treated with this drug. This impurity can be determined by GC/MS and LC/MS techniques. N,N'-Bis(2'-cyanobenzyl)-6-chloro-2,4-dioxopyrimidine is also found as a metabolite in rats and humans as well as being an analytical reference material for API impurities. The metabolite may be formed</p>

<p>N-Ethylcarbamic acid 3-[(1S)-1-(dimethylamino)ethyl]phenyl ester-d6 is a drug product that is used as an analytical standard for the determination of natural and synthetic impurities in API. It is also used to synthesize other compounds, such as N-methylcarbamic acid 3-[(1S)-1-(dimethylamino)ethyl]phenyl ester-d6. The CAS number for this compound is 1070660-34-2. This compound has a purity level of 99% and can be purchased from Sigma Aldrich with a purity level of 98%.</p>

<p>(6-Hydroxy-2-(4-hydroxyphenyl)-7-[4-(2-piperidin-1-yl-ethoxy)benzoyl]-benzo[b]thien-3-yl]-[4-[2-(1-piperidinyl)ethoxy]phenyl]methano ne) is a synthetic drug product that has been custom synthesized for the purpose of research and development. This compound is not found in nature, but it may be present as a metabolite. The main impurity in this compound is (5,7,8,9,10,11,12)-(6H)-5H-[1]benzopyrano-[2,3:6,7][2]oxathiazine. Metabolism studies have been done on rats and humans to determine how the compound is broken down. It was determined that the liver enzyme CYP3A4 was responsible for the</p>

<p>Please enquire for more information about α-Glycerophosphoric acid dicyclohexylammonium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-[(R)-[(1S)-2-Methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetic acid is a metabolite of the drug product, 2-[(S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinic acid. It is an impurity standard for the analytical determination of 2-[(S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinic acid in both drug products and in synthetic intermediates. The pharmacopoeia states that this compound should be present at less than or equal to 1% in drug products. This metabolite has been shown to have antiinflammatory activity.</p>

<p>Please enquire for more information about Diphenyl sulfone-3,3'-disulfonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Remdesivir impurity 5 is a metabolite that is generated in the body following metabolism and excretion of remdesivir. It has been shown to be present in urine, plasma, and cerebrospinal fluid following administration of remdesivir. Remdesivir impurity 5 binds to the active site of HIV reverse transcriptase with a Kd value of 0.5 nM. The chemical name for this compound is (5R)-3-[[3-[(2S,4R)-2-amino-4-(2-methylpropyl)piperidin-1-yl]-1H-indol-6-yl]carbonyl]benzoic acid methyl ester.</p>

<p>Sinalexin is an anticancer drug that targets human protein kinases. It is an analog of saxagliptin and has been shown to inhibit the growth of tumor cells in vitro. Sinalexin works by inhibiting the activity of protein kinases, which are enzymes that play a critical role in cell division and proliferation. In addition to its anticancer properties, Sinalexin has also been shown to induce apoptosis in cancer cells. This drug is excreted primarily in urine and has potential as a novel class of kinase inhibitors for the treatment of various types of cancer.</p>

<p>2-Methoxy-5-sulfamoylbenzamide is a white crystalline solid that is soluble in water. This compound has been shown to be an antiemetic agent, and also possesses antidopaminergic properties. It is used as an antiemetic, but has not been studied extensively for this indication. 2-Methoxy-5-sulfamoylbenzamide has also been shown to be effective in the treatment of Parkinsonism.</p>

<p>Please enquire for more information about 6β-Hydroxy 21-acetyloxy budesonide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>The human red blood cell (RBC) is a non-nucleated cell in the human blood that carries oxygen to the body's cells. The erythrocyte is characterized by its biconcave shape and its lack of organelles. It has a volume of about 80 fL, and a diameter of about 7 micrometers. The RBCs are produced in bone marrow from precursor cells that differentiate into erythroid progenitor cells. This drug binds to the hemoglobin molecules in the red blood cells and alters their shape, causing an increase in their deformability. In addition, this drug decreases the viscosity of the plasma outside of the red blood cell, which increases its extravascular sensitivity. Evaluations have been performed on low doses to evaluate sensitivities within capillaries with microscopy parameters such as magnification and resolution. These evaluations have shown that this drug can be used for quantifying changes in capillary size due to low doses (</p>

<p>Defluoropitavastatin calcium salt is a synthetic, high purity, pharmacopoeia drug product. It is a metabolite of pitavastatin and has been shown to have similar pharmacological activity. Defluoropitavastatin calcium salt has a niche in the analytical industry due to its high purity and stability. It has been used as an impurity standard for HPLC analysis. Defluoropitavastatin calcium salt is not found in nature and can be synthesized with the help of our Custom Synthesis service.</p>

<p>Bisoprolol impurity G is a metabolite of bisoprolol. It is the standard for bisoprolol impurities and is used as an analytical reference material for the quality control of bisoprolol.</p>

<p>Oxybutynin EP impurity B is a metabolite of oxybutynin and is a natural product. It is used as an analytical reference substance, to develop new drugs, and in pharmacopoeia in order to measure the purity of oxybutynin. The compound is synthesized by chemical synthesis and can be used as a standard for HPLC analysis.</p>

<p>Palbociclib Impurity F is a high purity synthetic intermediate for the production of Palbociclib. It is made by reacting 4-chloro-3-[4-(4-methylpiperidinium)butyl]benzoic acid with 3,5-dichloro-2-hydroxybenzaldehyde in the presence of triethylamine and 2,6-diisopropylaniline. This product has been shown to be metabolized through an oxidation process to form metabolites that are structurally similar to those found in urine. The chemical structure of this impurity can be found in CAS No. 851067-56-6.</p>

<p>Please enquire for more information about (R)-L 888607 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

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<p>Metformin EP Impurity B Dinitrate is a metabolite of metformin. Metformin is a drug product that belongs to the class of anti-diabetes drugs. It is used in the treatment of type II diabetes mellitus and has been shown to be effective in reducing blood sugar levels, as well as improving insulin sensitivity and lowering cholesterol levels. Metformin EP Impurity B Dinitrate is a synthetic impurity standard for HPLC analysis of metformin. This impurity is an analytical impurity in the drug product, but it does not have any clinical significance.</p>

<p>N,N-dimethyl-2-[(3-methylphenyl)phenylmethoxy]ethanamine is a metabolite of amphetamine. It is a synthetic drug that is used in the research and development of drugs. Its chemical name is 2-[(3-methylphenyl)phenylmethoxy]N,N-dimethyl ethanamine. It is also known as 3,4-dihydroxyphenethylamine and N,N-dimethylamphetamine. This compound has been found to be an impurity standard in amphetamine products. The CAS number for this compound is 21945-86-8.</p>

<p>3-O-Desethyl-5-O-desmethyl amlodipine is a drug product that can be used as an analytical reference standard. It is metabolized in vivo to form 5-O-desmethyl amlodipine, which is the active form of this drug. 3-O-Desethyl-5-O-desmethyl amlodipine is also an impurity in the drug product Amlodipine besylate and its CAS number is 1821498-25-2. The synthetic route for this compound starts with the reaction of 2,3,4,6 trichlorobenzeneethanol with sodium hydroxide followed by hydrogenation of the intermediate to yield 3-(2,6 dichlorophenyl) propanoic acid. This acid was then reacted with methylamine to yield 3-(2,6 dichlorophenyl)-N-[(methylamino) methyl]propionamide.</p>

<p>Please enquire for more information about 2,2',3,4,4',5,6,6'-Octabromodiphenyl ether including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Etifoxine-d3 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Bendamustine deschloro dimer impurity is a Chinese medicinal compound that acts as an inhibitor of kinases, which are enzymes that play a crucial role in the regulation of cell growth and division. It has been shown to induce apoptosis, or programmed cell death, in tumor cells and has anticancer properties. Bendamustine deschloro dimer impurity works by inhibiting the activity of protein kinases, which are involved in signaling pathways that control cell proliferation and survival. This compound has been identified as an analog of other kinase inhibitors and can be detected in urine samples from human patients receiving cancer treatment with bendamustine. In preclinical studies, it has demonstrated potent anti-tumor effects against various types of cancer cells.</p>

<p>25-Hydroxy vitamin D3 3-sulfate sodium salt is a unique compound that exhibits various characteristics and functions. It is derived from dimethyl fumarate, tenofovir, dopamine, and other substances. This compound acts as a steroid and plays a crucial role in maintaining the body's overall health.</p>

<p>Deiodo amiodarone hydrochloride is an analog of the drug amiodarone, which is used to treat cardiac arrhythmias. It has been shown to be a potent inhibitor of the nalbuphine-induced activation of human kinases, which are involved in cancer cell proliferation and survival. Deiodo amiodarone hydrochloride has been found to induce apoptosis in cancer cells by inhibiting protein kinase activity. This medicinal compound has also been tested for its anticancer properties in Chinese hamster ovary cells and urine tumor models, where it demonstrated significant inhibition of tumor growth. Overall, deiodo amiodarone hydrochloride shows great potential as an effective inhibitor for various types of cancers.</p>

<p>BMS 326412 is an analog inhibitor of several kinases that have been implicated in cancer. It induces apoptosis, or programmed cell death, in tumor cells by inhibiting the activity of specific proteins involved in cancer cell growth and proliferation. BMS 326412 has shown promise as an anticancer agent in both preclinical and clinical studies, with Chinese medicinal urine being used as a source for its synthesis. This compound has the potential to be a valuable addition to current cancer therapies due to its ability to selectively target cancer cells while leaving healthy cells unharmed.</p>

<p>Please enquire for more information about Losartan azide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Hydroxy cephalexin is a metabolite of cephalexin. It is an impurity that is present in the final drug product. 2-Hydroxy cephalexin has been used as an analytical standard and as a HPLC standard for quantification of cephalexin. 2-Hydroxy cephalexin is also used as a research and development tool for drug development.</p>

<p>Pemetrexed is a drug product that belongs to the group of drugs called antifolate agents. It is used in the treatment of cancer and is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The impurity C is a natural metabolite that can be found in urine as well as in plasma. This impurity has not been identified as a major metabolite of pemetrexed.</p>

<p>7-O-methyl ivermectin is a drug product that is an analytical standard for the impurity 7-O-methyl ivermectin B1a. Impurity 7-O-methyl ivermectin B1a is a natural API that is found in the synthesis of Ivermectin. It has a CAS number of 90589-08-4 and is produced through custom synthesis. This impurity can be used as an analytical standard for HPLC methods, such as high purity and pharmacopoeia grade. 7-O-methyl ivermectin B1a has shown to have little or no activity against bacteria, fungi, or parasites.</p>

<p>Methyl 4-[(5-amino-1-methylindol-3-yl)methyl]-3-methoxybenzoate is a metabolite of the drug methyl 3-[(5-amino-1-methylindol-3-yl)methyl]benzoate. It is a white solid that is soluble in alcohol, acetone, and chloroform. Methyl 4-[(5-amino-1-methylindol-3-yl)methyl]-3 methoxybenzoate has been used as an impurity standard for HPLC analysis of methyl 3-[(5 aminio 1 methyl indol 3 yl) methyl] benzoate. This chemical has also been investigated for its antiinflammatory properties.</p>

<p>13-Ethyl-17-hydroxy-18,19-dinor-17a-pregn-5(10)-en-20-yn-3-one EP is an analytical standard and an impurity. It is used as the reference substance for HPLC drug analysis. It is also a metabolite that can be found in drugs such as metoprolol, clonidine, and propranolol. 13EP was first synthesized by a custom synthesis company to meet the needs of niche drug products. The synthetic compound has been shown to be natural and it is not chemically related to any other compounds.</p>

<p>Hydrocortisone impurity G is a hydrocortisone derivative that has been shown to be an inhibitor of the estradiol dehydrogenase, which is responsible for converting estradiol to estrone. It also inhibits the conversion of cortisol to cortisone and can thus be used as a model system in order to study the effects of corticosteroids on oxidation reactions. Hydrocortisone impurity G is present in animal products, such as meat, milk, and eggs, at concentrations of up to 2.5%. This impurity can also be found in vegetable oils and fats at concentrations of up to 1%. The presence of this compound has been confirmed by gas chromatography-mass spectrometry (GC-MS). Hydrocortisone impurity G is not known to have any adverse effects on humans.</p>

<p>4-Methyl-3-[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide is a synthetic compound that has been used as an impurity standard to determine the purity of drugs. It is also used in research and development, drug product, and custom synthesis. 4-Methyl-3-[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide has a CAS number of 851137-91-2 and is on the list of pharmacopoeias. This compound is not found in nature, but it can be synthesized in the laboratory. Metabolism studies have been conducted for this drug to identify its metabolites, which can be determined through HPLC analysis.</p>

<p>Racemic norphenylephrine hydrochloride is a sympathomimetic amine. It is the racemic mixture of two enantiomers: (+)-noradrenaline and (-)-isopropyladrenaline. Racemic norphenylephrine hydrochloride has been shown to have antimicrobial activity by inhibiting bacterial growth, as well as being effective in treating autoimmune diseases and chronic oral disorders such as constipation. Racemic norphenylephrine hydrochloride can also be used for the treatment of cardiac diseases, including chronic heart failure, coronary artery disease, or hypertension. In addition, Racemic norphenylephrine hydrochloride can be used to treat detrusor muscle dysfunction (e.g., urinary incontinence).</p>

<p>Please enquire for more information about 3-(1,1-Difluoro-2-propen-1-yl)-2(1H)-quinoxalinone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Amiodarone is a drug product that is used in the treatment of various heart conditions. It contains impurity G and HCL. Impurity G is a metabolite that is found in the urine of patients who have taken Amiodarone and can be detected by HPLC. Impurity G has not been shown to be toxic to humans, but it may interfere with the metabolism of other drugs. The impurity standard for Amiodarone includes Impurity G, which is an analytical impurity, and Impurity HCL, which is an API impurity.</p>

<p>Dibenzhydryl disulfide is a compound that includes sulfide and olefinic groups. It is an impurity in the reaction products of sulfide with olefins, which may be removed by washing, distillation, and crystallization. Dibenzhydryl disulfide has been shown to react with nucleophiles (e.g., OH-, CO2) to form an anion or proton. The reaction mechanism for this product is not well understood, but it most likely proceeds through the intermediacy of diphenylmethane. The product can also undergo a transfer reaction with butyllithium or thiobenzophenone to form methylbenzene, ethylbenzene, or propylbenzene respectively.</p>

<p>Methocarbamol-d5 β-D-glucuronide is a synthetic drug product. It has CAS number 56305-74-9. This product is a metabolite and an impurity standard for methocarbamol. The material is a white powder that contains no detectable amount of nitrogen or water, with a purity greater than 99%. The product is intended for use in metabolism studies, natural products research and development, drug development, and pharmacopoeia.</p>

<p>Valdecoxib 3'-sulfonamide is a synthetic, non-naturally occurring drug product that has been custom synthesized for the purposes of research and development. It is not a natural API nor is it an impurity standard. This compound has been developed as a new lead compound for pharmacological studies and drug development, with an emphasis on high purity standards. The CAS number for this compound is 1373038-56-2.</p>

<p>4,6-Dimethoxy-β-methyl-3-phenoxy ambrisentan is a synthetic drug with a high purity and pharmacopoeia. It belongs to the group of drugs called prostanoids, which are lipid molecules that act as hormones. 4,6-Dimethoxy-β-methyl-3-phenoxy ambrisentan is used in research and development for the treatment of pulmonary arterial hypertension. It is an impurity standard for HPLC analysis. This compound can be custom synthesized for drug product research and development. Metabolism studies have been conducted on this compound. The metabolites have been identified as 4,6-dimethoxy-(E)-2-[(E)-2-(4'-methylbenzylidene)ethenyl]-3-[(Z)-1-(4'-methylbenzylidene)ethenyl]ambrinol (M1), 4,6-dimethoxy-(E)-</p>

<p>5,6-Dehydro-17beta-dutasteride is a synthetic drug product that is used as an analytical standard for the determination of metabolites and impurities in pharmaceuticals. It also has been used as a natural metabolite, which can be found in human urine. 5,6-Dehydro-17beta-dutasteride is a metabolite of dutasteride, which is an antiandrogen medication for the treatment of benign prostatic hyperplasia (BPH). It is also known to inhibit the metabolism of other drugs such as ketoconazole and metoprolol.</p>

<p>11-Cis-3,4-didehydro retinal is an analog of retinal that has been shown to inhibit apoptosis in human cells. It is a protein kinase inhibitor that has potential anticancer properties. This compound has been found in urine and has been studied for its ability to inhibit the growth of cancer cells. 11-Cis-3,4-didehydro retinal is a potent inhibitor of kinases such as nifedipine-sensitive protein kinase and Chinese hamster ovary cell kinase. Studies have shown that this compound can induce apoptosis in tumor cells and may have potential as an anticancer agent.</p>

<p>Please enquire for more information about 8-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-1-octen-4-ol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (2S)-2-Amino-3-methoxy-N-(phenylmethyl)propanamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3,3’-Carbonylbis(oxy)bis(2-phenylpropane-3,1-diyl) dicarbamate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Oxo-mirabegron N-carbamoylglucuronide (2OMGC) is an impurity of mirabegron, a drug used to treat overactive bladder. 2OMGC is a metabolite of mirabegron that is created through the hydrolysis of the carbamate group on the nitrogen atom. This impurity can be detected in HPLC and GC/MS analyses and has been found in the urine of patients taking mirabegron. The detection limit for this impurity is 10 ng/mL. 2OMGC exhibits pharmacological activity similar to that of its parent compound, mirabegron, which is purported to have antispasmodic and anal sphincter relaxant properties.</p>

<p>Ys-035 hydrochloride is a drug product that is custom synthesized and has no CAS number. It has a high purity and analytical results, as well as metabolism studies. This chemical is natural and the drug development stage is Pharmacopoeia or Metabolite. Synthetic and impurity standards are available for research and development, HPLC standard.</p>

<p>Apomorphine is a medicinal compound that has shown potential as an anticancer agent. It works by inhibiting protein kinases, which are enzymes that play a crucial role in the regulation of cell cycle and apoptosis. Apomorphine has been shown to induce apoptosis in human cancer cells, including leukemia cells. It also acts as an inhibitor of angiogenesis, which is the formation of new blood vessels that are necessary for tumor growth. In addition, apomorphine has been studied for its potential to enhance the effectiveness of other cancer treatments, such as nintedanib. Its ability to target cancer cells while sparing healthy cells makes it a promising candidate for cancer therapy.</p>

<p>5-Desbromo, 5-chloro brimonidine is a drug product that is used as an analytical standard. It has been shown to be metabolized by CYP3A4 and CYP2D6 enzymes.</p>

<p>N-Ethyl fluprostenol carboxamide is a synthetic compound with a chemical formula of C17H21NO4. It is an ester that has been shown to be prodrug for the active form, fluprostenol. N-Ethyl fluprostenol carboxamide is a molecule that contains two hydroxyl groups, one on the carboxamide group and one on the ethyl group. The chemical structure also contains a halogen atom and an ester group.</p>

<p>PBB 154 is a medicinal compound that has shown promising results in the treatment of cancer. This analog of a kinase inhibitor has been found to inhibit the activity of kinases, which are enzymes that regulate cell cycle progression and play a critical role in tumor growth. PBB 154 has been shown to induce apoptosis, or programmed cell death, in cancer cells. This compound has also been found to be effective against various types of cancer, including breast, prostate, and lung cancer. PBB 154 is an anticancer agent that works by inhibiting the activity of proteins involved in cell division and promoting apoptosis in cancer cells. It can be detected in urine and has potential for use as a diagnostic tool for detecting early stages of cancer.</p>

<p>Please enquire for more information about CXCR2-IN-2 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Dehydronitrosonisoldipine is a pyridine-containing compound that has been synthesized from dehydronitrosodiphenylamine. It is an ionic liquid with a melting point of 114°C and a boiling point of 272°C. Dehydronitrosonisoldipine has been shown to be active against some bacterial strains, but not others. It is effective for the treatment of infectious diseases such as H. influenzae, M. tuberculosis, and Listeria monocytogenes in animal studies. This compound also shows efficacy against some bacteria that are resistant to antibiotics such as penicillin and erythromycin in vitro. The molecular weight of dehydronitrosonisoldipine is 262.2 g/mol and its molecular formula is C12H14N2O4S2D6N2O6.</p>

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<p>base ethylated deoxy-guanosine nucleoside</p>

<p>4-(Acetylamino)-3-bromobenzenesulfonyl chloride is a white crystalline powder that is soluble in water, ethanol and chloroform. It has an analytical standard purity of 99% or greater. This compound can be used for research and development purposes as well as for the synthesis of pharmaceuticals. The impurity profile of 4-(acetylamino)-3-bromobenzenesulfonyl chloride includes 3-acetylbenzenesulfonic acid, sodium acetate, ammonium chloride, sodium sulfite, potassium bromide, potassium iodide, potassium carbonate, and potassium citrate.</p>

<p>Please enquire for more information about 2,5-Dioxabicyclo[2.2.1]heptane α-D-galactopyranoside including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>6,6-Dibromopenicillanic acid S,S-dioxide (DBPA) is an inorganic compound that is used as an antibiotic. It inhibits the growth of bacteria by binding to the 50S ribosomal subunit and preventing the formation of a complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division. DBPA degrades lactamase enzymes that are necessary for resistance to this antibiotic. This chemical also has a high degree of stability against hydrochloric acid, which makes it useful in organic solvents. It is resistant to many resistant bacteria due to its mechanism of action and lack of substrate specificity.</p>

<p>Vandetanib N-oxide is a drug product that is custom synthesized for research and development purposes. It has been shown to have high purity, analytical, and natural properties. Vandetanib N-oxide can be used as a metabolite or impurity standard in pharmacopoeias, such as the USP. The compound also has niche use in drug development and metabolism studies.</p>

<p>N-(2-Hydroxyethyl)-P,P-bisaziridinyl thiophosphamide (HEPBTP) is a metabolite of the drug product. HEPBTP is synthesized from the parent compound by hydrolysis and oxidation reactions. This metabolite has been characterized using HPLC and analytical methods, including mass spectrometry. It is also included in the pharmacopoeia as an impurity standard for quality control.</p>

<p>Please enquire for more information about N-Formyl-3,5-diiodo-L-tyrosine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Oxodesmosine is an analog of a protein found in Chinese urine that has shown promise as an anticancer agent. It works by inhibiting kinases, which are enzymes that play a key role in cancer cell growth and survival. Oxodesmosine has been shown to induce apoptosis, or programmed cell death, in tumor cells both in vitro and in vivo. This compound may be useful as a therapeutic agent for the treatment of various types of cancer in humans. Additionally, Oxodesmosine has been studied for its potential synergistic effects with other kinase inhibitors such as mirtazapine. Overall, Oxodesmosine represents a promising new avenue for the development of novel anticancer therapies.</p>

<p>Rotigotine is a drug that belongs to the group of pharmaceutical formulations. It is an unlabeled drug that has been shown to be effective in the treatment of depression. Rotigotine may be administered through a transdermal patch or by iontophoresis, which is a technique used to administer drugs through the skin. The mechanism of action is not known, but it may involve the inhibition of monoamine reuptake and/or alteration of intracellular levels of catecholamines. Rotigotine sulfate has a high affinity for dopamine receptors and increases plasma concentrations of dopamine by inhibiting its reuptake into presynaptic neurons. This leads to increased concentrations of dopamine in synaptic clefts and an increase in postsynaptic receptor binding.</p>

<p>Alpha-[4-(2-dimethylaminoethoxy)phenyl]stilbene (DS) is a synthetic, analytical standard that is used as an impurity in the manufacture of pharmaceutical products. DS is also sold as a reference material for HPLC and GC/MS analysis.</p>

<p>Please enquire for more information about 3’-Epi gemcitabine 3’,5’-dibenzoate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Tri-o-(tert-butyldimethylsilyl) ractopamine is a compound that has been studied for its potential biological effects. It has been shown to have antioxidant properties, as it reduces the levels of malondialdehyde and IL-17A, which are markers of oxidative stress and inflammation. The compound's coordination geometry allows it to interact with fatty acid hydroperoxides and other complex molecules, potentially influencing their biological activity. Additionally, tri-o-(tert-butyldimethylsilyl) ractopamine can act as a cation, neutralizing reactive species that contribute to lipid peroxidation. Studies have also found impurities in this compound, which may affect its overall effectiveness. Further research is needed to fully understand the chemokine and human serum interactions of tri-o-(tert-butyldimethylsilyl) ractopamine.</p>

<p>Endothion is a medicinal compound that has shown promising anticancer properties. It is an analog of a kinase inhibitor found in Chinese herbal medicine and has been shown to inhibit the activity of kinases involved in cancer cell growth and survival. Endothion induces apoptosis, or programmed cell death, in cancer cells by inhibiting protein synthesis and disrupting cellular processes necessary for tumor growth. Studies have also shown that Endothion can be excreted through urine, making it a potential non-invasive diagnostic tool for cancer detection. This compound is currently being researched as a potential treatment option for various types of cancer.</p>

<p>Please enquire for more information about Defluoro pitavastatin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(R)-Penbutolol sulfate is a racemic mixture of the two enantiomers of penbutolol. Racemic penbutolol sulfate is an optical isomer of propranolol, which belongs to the group of beta-adrenergic receptor antagonists. It has a matrix effect, which means that it can be used in tablet form and will not dissolve in the stomach acid. Racemic penbutolol sulfate blocks pro-inflammatory signaling by inhibiting the activity of pcsk9 (proprotein convertase subtilisin/kexin type 9), which prevents cholesterol from being converted into bile acids. This drug has been shown to lower blood pressure in humans and is used to treat hypertension and heart failure. Racemic penbutolol sulfate has been shown to have an inhibitory effect on influenza virus replication through inhibition of viral dna replication, as well as enhancement on anti-pcsk9 antibody activity. In clinical trials</p>

<p>3-Sulfanilamidoisoxazole sodium is a Chinese medicinal compound that has shown promising results in the treatment of cancer. It is an analog of sulfanilamide and works by inhibiting protein synthesis and inducing apoptosis in cancer cells. 3-Sulfanilamidoisoxazole sodium has been shown to inhibit the activity of various kinases, which are enzymes involved in cell cycle regulation and tumor growth. This compound has also been found to be effective against a variety of human cancers, including breast, lung, and prostate cancer. Additionally, it has been shown to have low toxicity levels and can be excreted through urine. With its potent anticancer properties, 3-Sulfanilamidoisoxazole sodium holds great promise as a potential inhibitor for cancer therapy.</p>

<p>Please enquire for more information about Apixaban rc G including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>