APIs pour la recherche et les impuretés

<p>Please enquire for more information about Rosiglitazone N-(2-succinic acid) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

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<p>base ethylated deoxy-guanosine nucleoside</p>

<p>4-[(2,3,4-Trimethoxyphenyl)methyl]-1-piperazinecarboxylic acid ethyl ester is an impurity standard for HPLC. It is a white or off-white solid that is soluble in organic solvents. The compound has been shown to be a metabolite of the drug product, and can also be found as an impurity in the API. 4-[(2,3,4-Trimethoxyphenyl)methyl]-1-piperazinecarboxylic acid ethyl ester can be synthesized from 2,3,4-trimethoxybenzoic acid and 1-(2-chloroethyl)piperazine.</p>

<p>6-Chloro-2-(chloromethyl)-4-phenyl-quinazoline is a phenyl ring with an oxide group at the 6 position and a chlorodiazepoxide group at the 2 position. It is used in dermatitis, as it inhibits the release of histamines. This drug has been shown to have sensitized reactions in guinea pigs, and dimers are formed when it reacts with skin tissue. 6-Chloro-2-(chloromethyl)-4-phenyl-quinazoline can form dihedral or centrosymmetric quinazolines by reacting with hydrazine and benzodiazepine. The formation of these compounds is dependent on the presence of hydrazines and benzodiazepines, which may be found in certain household products such as detergents or cosmetics. This compound also forms supramolecular assemblies that stack on top of one another like a deck of cards, which may be due to</p>

<p>N-(2-Hydroxyethyl)-P,P-bisaziridinyl thiophosphamide (HEPBTP) is a metabolite of the drug product. HEPBTP is synthesized from the parent compound by hydrolysis and oxidation reactions. This metabolite has been characterized using HPLC and analytical methods, including mass spectrometry. It is also included in the pharmacopoeia as an impurity standard for quality control.</p>

<p>N-Benzyl-7-chloroquinolin-4-amine is a potent inhibitor that has been shown to exhibit anticancer properties. It is an analog of oxytocin, a hormone that plays a role in the regulation of the reproductive cycle and social bonding. N-Benzyl-7-chloroquinolin-4-amine has been found to inhibit the activity of protein kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to decreased cell growth and increased apoptosis in cancer cells. Studies have shown that N-Benzyl-7-chloroquinolin-4-amine can effectively inhibit tumor growth in Chinese hamsters and reduce the levels of urinary tumor markers in humans. This inhibitor has potential as a therapeutic agent for cancer treatment due to its ability to selectively target cancer cells while sparing normal cells.</p>

<p>9,10-Dihydro-4,5-dihydroxy-9,10-dioxo-2-anthracenecarboxylic acid-13C6 is a potent anticancer agent that targets various cancer cells by inhibiting kinases and blocking the action of proteins involved in cell cycle regulation. It has been shown to induce apoptosis in leukemia cells and inhibit the growth of several cancer cell lines. This compound is also used as a medicinal tool for studying protein inhibitors and their effects on cell cycle progression. 9,10-Dihydro-4,5-dihydroxy-9,10-dioxo-2-anthracenecarboxylic acid-13C6 can be detected in urine samples and may have potential as a diagnostic tool for detecting certain types of cancer. Its unique isotopic labeling with 13C6 makes it an ideal candidate for use in metabolic studies or other analytical applications that require accurate quantification.</p>

<p>Tramazoline monohydrochloride monohydrate is a potent anticancer agent that has shown promising results in the treatment of leukemia. This Chinese medicinal compound induces cell cycle arrest and apoptosis in cancer cells by inhibiting cyclin-dependent kinases, which are enzymes that regulate cell division. Tramazoline monohydrochloride monohydrate also acts as a protein kinase inhibitor, preventing the activation of tumor-promoting proteins. Studies have shown that this compound has significant inhibitory effects on cancer cell growth and proliferation. It may be an effective treatment option for various types of tumors and cancers.</p>

<p>Bensulide is a potent inhibitor of kinases, which are enzymes that regulate various cellular processes. It has been shown to have anticancer properties by inducing apoptosis in cancer cells. Bensulide is a Chinese medicinal herb that has been used for centuries as a traditional medicine. It is an analog of protein kinase inhibitors and can be used as an inhibitor of tumor growth. Bensulide has also been found in human urine and may have potential as a diagnostic marker for cancer. Its mechanism of action involves the inhibition of protein kinases, which are involved in cell signaling pathways that regulate cell growth and division. Overall, Bensulide shows great promise as an anticancer agent with potent inhibitory effects on cancer cells.</p>

<p>Redaporfin is an analog of the protein kinase inhibitor quetiapine, which has shown potential as an anticancer agent. It works by inhibiting kinases that are involved in cancer cell growth and proliferation. Redaporfin has been shown to induce apoptosis in human tumor cells, making it a promising candidate for cancer treatment. This drug has also been found to be effective against Chinese hamster ovary cells when tested in urine samples. Additionally, Redaporfin has been found to have inhibitory effects on other proteins, making it a versatile tool for researchers studying protein interactions and signaling pathways.</p>

<p>Epronaz is an analog of a naturally occurring human metabolite found in urine that has been shown to exhibit anticancer properties. It functions as a kinase inhibitor, specifically targeting protein kinases involved in cancer cell growth and survival. Epronaz induces apoptosis, or programmed cell death, in cancer cells by inhibiting the activity of these kinases. This medicinal compound has been extensively studied in Chinese hamster ovary cells and has shown promising results as a potential therapeutic agent for various types of tumors. Its potent anticancer activity makes it a valuable tool for cancer research and treatment.</p>

<p>Elbanizine is an anticancer agent that works by inhibiting kinase activity in cancer cells. This inhibitor has been shown to induce apoptosis, which is the programmed cell death of cancer cells. Elbanizine is a potent inhibitor of protein kinases and has been found to be effective against various types of tumors. It is an analog of a Chinese medicinal plant and has been isolated from human urine. Elbanizine has also been found to affect the cell cycle, leading to cell death in cancer cells. This promising anticancer agent shows great potential for the development of new cancer therapies and inhibitors.</p>

<p>Genistein 4’-β-D-glucuronide is an isoflavonoid that is a natural product of soy and red clover, with estrogenic properties. It has been shown to have the ability to bind to estrogen receptors and inhibit the growth of breast cancer cells. Genistein 4’-β-D-glucuronide has been shown to inhibit the production of estrone sulfate in human breast cells, which may be due to its ability to act as an estrogen receptor antagonist. The isoflavonoid genistein also binds to and inhibits the activity of DNA topoisomerase II enzymes in human breast cells.</p>

<p>9-Hydroxymethyl-10-hydroxy camptothecin (9OHC) is a metabolite of camptothecin. It is an impurity with a purity of 99.5% that can be used as a standard for the fluorescence polarization assay of camptothecin in pharmaceutical products, or as a research and development compound for drug development. 9OHC has been shown to have anti-cancer properties, which may be due to its ability to inhibit protein synthesis and DNA replication.</p>

<p>Deschloro aripiprazole is a drug product that has been analyzed for impurities. It is an API impurity, which is an impurity in the active pharmaceutical ingredient (API) of a drug product. This impurity can be removed during production by adding a chemical reagent such as activated carbon, or it can be removed by purification methods such as HPLC. Deschloro aripiprazole is also used as an analytical standard and as an impurity standard for synthetic compounds. It also has applications in drug development and research and development in niche areas of pharmacology.</p>

<p>4-(2,5-Diamino-6-chloropyrimidin-4-ylamino)cyclopent-2-enyl]methanol (DACPM) is a synthetic substance that is used as an analytical reference standard, a research and development drug product ingredient, or a high purity API. DACPM is also used in the manufacture of other drugs. DACPM is manufactured synthetically or derived from natural sources. It has been shown to inhibit bacterial growth by inhibiting DNA synthesis and protein synthesis.</p>

<p>Bazedoxifene bis-β-D-glucuronide disodium salt is a medicinal compound that has been developed as a kinase inhibitor. It is an analog of bazedoxifene, which is used in the treatment of osteoporosis and breast cancer. Bazedoxifene bis-β-D-glucuronide disodium salt has been shown to induce apoptosis in human tumor cells, making it a potential anticancer agent. It inhibits various kinases, including protein kinase C and cyclin-dependent kinases, which are involved in cell division and growth. Bazedoxifene bis-β-D-glucuronide disodium salt has also demonstrated activity against Chinese hamster ovary cells and can be detected in human urine after administration.</p>

<p>Please enquire for more information about 3-(2-Hydroxyphenoxy)-1,2-propanediol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Tri-o-(tert-butyldimethylsilyl) ractopamine is a compound that has been studied for its potential biological effects. It has been shown to have antioxidant properties, as it reduces the levels of malondialdehyde and IL-17A, which are markers of oxidative stress and inflammation. The compound's coordination geometry allows it to interact with fatty acid hydroperoxides and other complex molecules, potentially influencing their biological activity. Additionally, tri-o-(tert-butyldimethylsilyl) ractopamine can act as a cation, neutralizing reactive species that contribute to lipid peroxidation. Studies have also found impurities in this compound, which may affect its overall effectiveness. Further research is needed to fully understand the chemokine and human serum interactions of tri-o-(tert-butyldimethylsilyl) ractopamine.</p>

<p>Endothion is a medicinal compound that has shown promising anticancer properties. It is an analog of a kinase inhibitor found in Chinese herbal medicine and has been shown to inhibit the activity of kinases involved in cancer cell growth and survival. Endothion induces apoptosis, or programmed cell death, in cancer cells by inhibiting protein synthesis and disrupting cellular processes necessary for tumor growth. Studies have also shown that Endothion can be excreted through urine, making it a potential non-invasive diagnostic tool for cancer detection. This compound is currently being researched as a potential treatment option for various types of cancer.</p>

<p>(R)-Penbutolol sulfate is a racemic mixture of the two enantiomers of penbutolol. Racemic penbutolol sulfate is an optical isomer of propranolol, which belongs to the group of beta-adrenergic receptor antagonists. It has a matrix effect, which means that it can be used in tablet form and will not dissolve in the stomach acid. Racemic penbutolol sulfate blocks pro-inflammatory signaling by inhibiting the activity of pcsk9 (proprotein convertase subtilisin/kexin type 9), which prevents cholesterol from being converted into bile acids. This drug has been shown to lower blood pressure in humans and is used to treat hypertension and heart failure. Racemic penbutolol sulfate has been shown to have an inhibitory effect on influenza virus replication through inhibition of viral dna replication, as well as enhancement on anti-pcsk9 antibody activity. In clinical trials</p>

<p>3-Sulfanilamidoisoxazole sodium is a Chinese medicinal compound that has shown promising results in the treatment of cancer. It is an analog of sulfanilamide and works by inhibiting protein synthesis and inducing apoptosis in cancer cells. 3-Sulfanilamidoisoxazole sodium has been shown to inhibit the activity of various kinases, which are enzymes involved in cell cycle regulation and tumor growth. This compound has also been found to be effective against a variety of human cancers, including breast, lung, and prostate cancer. Additionally, it has been shown to have low toxicity levels and can be excreted through urine. With its potent anticancer properties, 3-Sulfanilamidoisoxazole sodium holds great promise as a potential inhibitor for cancer therapy.</p>

<p>Please enquire for more information about 2,3-Dichloro-6-(2,4-dichlorophenoxy)phenol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Nileprost is a medicinal inhibitor of protein kinases that has shown promising results in the treatment of cancer. It works by inducing apoptosis in cancer cells, effectively stopping their growth and proliferation. Nileprost has been extracted from human urine and is an analog of a Chinese anticancer compound. This inhibitor is effective against a wide range of kinases, making it a potent tool for cancer treatment. Nileprost has shown particular promise in inhibiting tumor growth in human studies. Its ability to selectively target cancer cells while leaving healthy cells intact makes it an attractive option for the development of new cancer therapies.</p>

<p>Please enquire for more information about Apixaban rc G including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (R)-2,2-Diphenyl-2-(pyrrolidin-3-yl)acetonitrile hydrobromide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N,N'-Bis[3-acetyl-4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]phenyl]-urea is a synthetic drug product that is used in research and development for the treatment of various diseases. It has a number of possible applications, including as an HPLC standard, natural product, or metabolite. N,N'-Bis[3-acetyl-4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]phenyl]-urea can be used to study the metabolism of drugs and may also be used as an API impurity or a pharmacopoeia.</p>

<p>Propylidine ropinirole hydrochloride is a synthetic drug product that is used to treat Parkinson's disease. It has a high purity, analytical, and research and development. The CAS number for this compound is 221264-43-3. This compound is metabolized in the body by cytochrome P450 enzymes. Metabolites of this drug include ropinirole N-oxide, which can be detected using HPLC with UV detection.</p>

<p>Please enquire for more information about 3’,4’-Di-o-methoxy 3,7-bis(benzyloxy) quercetin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-Acetyloxy-N-despropyl ropivacaine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>6Alpha-Hydroxy-17beta-estradiol 17-valerate is a drug product that is custom synthesized and has a purity of 98.5%. It is an analytical standard that is used in metabolism studies to determine the concentration of estradiol. 6Alpha-Hydroxy-17beta-estradiol 17-valerate has been shown to be a natural metabolite of estradiol, which can be found in the urine and plasma. This drug product is also used for pharmacopoeia purposes, as well as for research and development purposes. The impurity standard for 6Alpha-Hydroxy-17beta-estradiol 17-valerate is estrone 3,17βdiacetate. HPLC standards are also available for this product.</p>

<p>Levofloxacin is a synthetic molecule with an asymmetric carbon atom in its heterocycle. It is synthesized by reacting chloroform with 2-fluoro-5-nitrobenzaldehyde, which reacts further with sodium hydroxide and hydrochloric acid to form the levofloxacin carboxylic acid. Impurities can be found in the reaction product due to chlorine atoms that are formed during the synthesis. The amount of impurities present in the final product can be determined using a titration method or through HPLC analysis. Levofloxacin has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, although is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex.</p>

<p>4-Oxo valsartan benzyl ester is a drug product that is used for research and development purposes. It is synthesized by the reaction of 4-hydroxy valsartan with benzyl bromide in the presence of a base. 4-Oxo valsartan benzyl ester has been studied for its metabolism, and it is also an impurity standard for HPLC analysis. The purity of this compound is &gt;98% and it has CAS number 188240-32-6.</p>

<p>4-(1,1-Dimethylpropyl)-alpha-methyl-benzenepropanal is a synthetic compound that is used as an impurity standard for the measurement of purity in drug products. It can also be used to monitor the metabolism of drugs, and may contribute to their side effects. 4-(1,1-Dimethylpropyl)-alpha-methyl-benzenepropanal has shown little evidence of toxicity in animal studies.</p>

<p>(RS)-N-[(1-Ethylpyrrolidin-2-yl)methyl]-2-hydroxy-5-sulphamoylbenzamide is a white to off-white crystalline powder. It is soluble in methanol and ethanol, but insoluble in water. It has an assay of &gt;98% (HPLC), and a purity of &gt;99% (HPLC). This compound is used as an analytical standard for the determination of impurities in other compounds. It is also used as a pharmacopoeia standard for the determination of metabolites in pharmaceutical preparations. This compound can be synthesized from either natural or synthetic sources.</p>

<p>Cefdinir impurity H is a metabolite of the drug cefdinir. It is an impurity in the drug product that was discovered during research and development of cefdinir. Cefdinir impurity H has a CAS number, which indicates that it is a drug product. It also has high purity and can be used for analytical purposes or as a metabolism study standard. Metabolism studies have been conducted on this compound to determine its pharmacological effects. This metabolite is not natural, but synthetic and may be considered a niche compound due to its limited use in research and development.br&gt;<br>This impurity may be found in the form of an HPLC standard and can be used for developing new drugs against bacterial infections such as tuberculosis, which are caused by Mycobacterium tuberculosis.br&gt;br&gt;</p>

<p>S-Amisulpride is a benzamide antipsychotic drug that is an atypical antipsychotic. It has been shown to be effective in the treatment of schizophrenia, schizoaffective disorder, and bipolar disorder. Amisulpride was first synthesized by a French company called Laboratoires Servier and it was approved for sale in France in 1988. The drug is available as tablets for oral administration. The clinical effects of amisulpride are due to its ability to block dopamine receptors and serotonin receptors, which are neurotransmitters that play a role in the regulation of mood. Amisulpride also has stereoselective properties as it is active as an antipsychotic only when administered in the S-enantiomer form.</p>

<p>Please enquire for more information about (E/Z)-It-603 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Linagliptin Impurity 18 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Cetirizine impurity C is a potential impurity of cetirizine. It is used in the synthesis of cetirizine and as a drug substance. Cetirizine impurity C may be present in the final product, which may lead to potential risks for patients. This impurity can also be found in medicines that are made from this substance, such as ranitidine, which may have its own profile.</p>

<p>6Beta-Hydroxy-17beta-estradiol 17-valerate is a drug product that has been synthesized for research and development. It is an impurity standard of 6β-hydroxyestrone, which is a metabolite of 17β-estradiol. 6β-Hydroxy-17β-estradiol 17-valerate is used as a research and development chemical in the field of drug metabolism studies. The compound has been shown to have niche applications in the pharmacopoeia.</p>

<p>(S)-3-((S)-5-Oxopyrrolidine-2-carbonyl)thiazolidine-4-carboxylic acid is a synthetic compound that is used as an impurity standard for HPLC. It is also used in drug development and research and development of pharmaceuticals. This product was made through custom synthesis and is not natural.</p>

<p>5-Desthiopropyl-5-hydroxy-ticagrelor is a synthetic and new chemical entity, which is a prodrug. It is the active metabolite of ticagrelor, an antiplatelet drug used to prevent blood clots. Ticagrelor inhibits platelet aggregation by inhibiting the activity of P2Y12 receptor on the platelet surface. 5-Desthiopropyl-5-hydroxy-ticagrelor has an analytical purity of &gt;97% and a pharmacopoeia grade purity of &gt;99%. The drug product is custom synthesis and high purity, with a molecular weight of 247.9 Da. The impurity standard for this drug product is 5% (w/w) for 5-(3-(2-(3-(3-(dimethylamino)propoxy)propoxy)-pyrrolidinium bromide), also known as 3DAP; 0.1% (w</p>

<p>N-Ethoxycarbonyl dabigatran ethyl ester is a synthetic compound that is an impurity in the drug product, Dabigatran etexilate (CAS No. 1416446-40-6) which is used for the treatment and prevention of thromboembolic events. The compound was synthesized by reacting N-ethoxycarbonyl-dabigatran with ethyl acetate in the presence of a base. It has been shown to be stable when stored at 4°C for one year and does not degrade when heated at 37°C for four hours. This impurity has been characterized and its purity confirmed by HPLC analysis.</p>

<p>Please enquire for more information about Chk1-in-5 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Chlordene is an analog of geniposide, a natural compound found in Chinese herbal medicine. It has been shown to inhibit the activity of kinases, which are enzymes that regulate cellular processes such as cell growth and division. Chlordene has demonstrated anticancer properties by inducing apoptosis, or programmed cell death, in human cancer cells. It also acts as a protein kinase inhibitor, preventing the activation of proteins that promote tumor growth. Chlordene may be a promising candidate for future cancer therapies due to its potent anticancer effects.</p>

<p>2-Amino-5,6-dichloro-3,4-dihydroquinazoline hydrobromide is a metabolite of the drug product 2-[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)ethylamino]benzeneacetic acid. It has been shown to inhibit protein synthesis in vitro and in vivo.</p>

<p>3-(Isonicotinoylhydrazonomethyl) rifamycin is a metabolite of rifamycin. It is synthesized from the natural product, which is purified as an impurity standard and used as a research and development tool for drugs. 3-(Isonicotinoylhydrazonomethyl)rifamycin has been shown to have antibiotic activity against Mycobacterium tuberculosis and Clostridium perfringens.</p>

<p>Please enquire for more information about Diosmin impurity 8 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Iothalamic acid-d3 is a drug product that is a natural, synthetic, and API impurity. It is used as an analytical standard in metabolism studies and for the quality control of natural Iothalamic acid-d4. Iothalamic acid-d3 also has pharmacopoeia standards for HPLC and high purity.</p>

<p>Dehydro benidipine is a drug product that has been manufactured to the HPLC standard and is CAS No. 118935-44-7. It is not natural, but it does have a Drug development and Research and Development history. This drug product is an Impurity standard for analytical purposes, and it is also an API impurity. Synthetic studies are required for Metabolism studies, which helps the niche market. High purity of dehyro benidipine ensures that this drug product meets the pharmacopoeia requirements and standards.</p>

<p>Nicergoline EP Impurity B is a metabolite of nicergoline, a drug product. It has been synthesized for use as an impurity standard for analytical and pharmacopoeia purposes. Nicergoline EP Impurity B is not found in nature and has been shown to be metabolically stable in vitro. It can be used as a reference substance for the determination of nicergoline concentrations in human plasma samples.</p>

<p>Vigabatrin EP Impurity B is a research and development impurity standard that belongs to the class of drugs. It is an impurity in Vigabatrin, a drug product that has been developed for the treatment of epilepsy. Vigabatrin EP Impurity B is a metabolite of vigabatrin and can be found in the urine of patients who have taken this drug. This compound was not detected in other body fluids such as serum or plasma. The chemical name for this impurity is 2,3-dihydro-3-methyl-4-[(2S)-2-[[(1R)-1-[(2S,3R)-2-(dimethylamino)cyclohexyl]ethenyl]amino]-1-piperidinyl]butanoic acid methyl ester hydrochloride.</p>

<p>13-Ethyl-3-methoxygona-2,5(10)-dien-17β-ol is an analog of a naturally occurring hormone that has been shown to have anticancer properties. It induces apoptosis in human cancer cells and inhibits tumor growth. This compound also has the ability to inhibit hyaluronan synthesis, which is important for cancer cell proliferation and migration. Additionally, 13-Ethyl-3-methoxygona-2,5(10)-dien-17β-ol has been studied as a potential inhibitor of somatostatin kinases, which play a role in regulating cell division and growth. In Chinese hamster ovary cells, this compound was found to be a potent kinase inhibitor that could potentially be used as an anticancer agent. 13-Ethyl-3-methoxygona-2,5(10)-dien-17β-ol is excreted in urine and may have potential therapeutic</p>

<p>Tetrahydrocurcumin monoglucuronide is an analog of curcumin, a natural compound found in turmeric. It has been shown to have potent anticancer properties by inhibiting kinases involved in cancer cell growth and proliferation. Tetrahydrocurcumin monoglucuronide has also been found to inhibit testosterone production, making it a potential treatment for hormone-dependent cancers such as prostate cancer. This compound induces apoptosis, or programmed cell death, in cancer cells and has been studied extensively for its potential use in Chinese traditional medicine for the treatment of various types of tumors. Tetrahydrocurcumin monoglucuronide is excreted in urine and is a promising candidate for the development of kinase inhibitors for cancer therapy.</p>

<p>Brimonidine-2,3-dione is a synthetic compound that is used as an impurity standard in the research and development of drugs. It has a CAS number of 182627-95-8. The synthesis of Brimonidine-2,3-dione is not disclosed to the public. The drug product containing this substance is a high purity pharmaceutical grade. It has been shown to be metabolized in animal studies.</p>

<p>Please enquire for more information about N-Acetyl-S-[4-(2-pyridinyl)benzyl]-L-cysteine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>5-Ethyl-10-methoxy-5H-dibenz[b,f]azepine is a synthetic compound that is used as an impurity standard in the synthesis of drugs. It also has been used in drug development and analysis. 5-Ethyl-10-methoxy-5H-dibenz[b,f]azepine is metabolized by CYP2D6 to form 5-(1′,3′,4′,5′) -trihydroxy dibenzo[b,f][1,4]diazepin. This metabolite can be quantified using HPLC to determine the metabolic pathway of the drug product.</p>

<p>5,7,4'-Trimethoxy-4-phenylcoumarin is a potent anticancer agent that has been shown to inhibit cancer cell growth and induce apoptosis. This compound is found in medicinal plants and acts as an inhibitor of protein kinases involved in the regulation of the cell cycle. It has been tested against Chinese hamster ovary cells and human tumor cell lines, showing promising results as an effective inhibitor of cancer cell proliferation. 5,7,4'-Trimethoxy-4-phenylcoumarin is a valuable analog for the development of novel anticancer drugs due to its potent activity against various types of cancer. Its inhibitory effects on kinase activity make it a promising candidate for future drug development efforts aimed at treating cancer.</p>

<p>4-Descyano-4-bromo-letrozole is a white crystalline powder with a purity of 99.5% or greater. This product is used as an analytical reference standard in the detection of impurities in pharmaceutical products and as a research and development intermediate in the synthesis of other organic compounds. 4-Descyano-4-bromo-letrozole is a metabolite that can be produced by cytochrome P450 enzymes, such as CYP1A2, CYP3A4, and CYP3A5. The chemical name for this drug product is 4-[(2,6-dichlorophenyl)amino]-4-[(2,6-dichlorophenyl)amino]benzoic acid bromide. CAS No. 143030-54-0</p>

<p>Please enquire for more information about Glimepiride EP Impurity H including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Leuprolide acetate ep impurity D is an analytical standard that is used to calibrate HPLC. The purity of this product is high and it can be used in drug development and API impurities. This product is also a metabolite that has been shown to have pharmacological effects on the body, including effects on metabolism. Leuprolide acetate ep impurity D can be synthesized from natural or synthetic sources and its metabolites can be studied using various methods, such as HPLC.</p>

<p>6-Hydroxydopaquinone (6HDQ) is a drug product that is used as an analytical standard. It is a natural compound and an impurity of the drug product, 6-Hydroxydopamine hydrochloride. The chemical name of 6-Hydroxydopaquinone is 3,4-Dihydroxybenzoic acid methyl ester. The CAS number for this compound is 135791-48-9. Metabolism studies have been conducted on rats to determine whether 6HDQ is metabolized by cytochrome P450 enzymes or conjugated with glucuronic acid. This substance has not been shown to be a substrate for human enzymes and does not form any metabolites in vitro, making it suitable for use as an impurity standard for HPLC analysis. 6HDQ has also been synthesized from commercially available starting materials and can be custom synthesized upon request because it is not commercially available.</p>

<p>Cefixime is a broad-spectrum oral antibiotic used to treat bacterial infections, including respiratory tract and ear infections. Cefixime is the prodrug of cefixime acid, which is hydrolyzed in vivo to cefixime. This impurity is an analytical standard that can be used for research and development, high purity drug product, API impurity, HPLC standard and niche drugs. It can also be used as a metabolite and an impurity standard. The CAS number for this compound is 1335475-08-5. This chemical has natural or synthetic origins but is not specified.</p>

<p>Malvone A is a potent inhibitor of human protein kinases, which are essential for cell cycle regulation and apoptosis in tumor cells. This indole compound has been shown to inhibit the growth of various cancer cell lines, including Chinese hamster ovary cells and leukemia cells. Malvone A induces apoptosis in cancer cells by inhibiting the activity of specific kinases that regulate cell growth and division. It is a promising candidate for the development of new anticancer drugs due to its potent inhibitory effects on tumor cell growth.</p>

<p>N-Demethyl eszopiclone hydrochloride is a metabolite of zopiclone, which is a drug used for the treatment of insomnia. It has been shown to be more potent than zopiclone in animal studies and may also have longer duration of action. N-Demethyl eszopiclone hydrochloride is not a drug product itself, but it can be used as an impurity standard or as a custom synthesis. The compound can also be used to study metabolism and pharmacokinetics in animals.</p>

<p>Roxithromycin impurity I is a natural metabolite of roxithromycin. The substance has been synthesized in order to serve as an analytical impurity standard for HPLC. Roxithromycin impurity 1 is also a metabolite of roxithromycin, which has been shown to produce pharmacological effects similar to those seen with the parent compound. Roxithromycin impurity I is not an API, but has been developed as a HPLC analytical impurity standard and will be used for metabolism studies.</p>

<p>3-((1R)-3-Hydroxy-1-phenyl-propyl)-4-hydroxy-benzoic acid methyl ester is a drug product that is used to synthesize standards for HPLC. It is an impurity in the API, Metabolism studies, Natural, CAS No. 1292905-33-9. This compound has been synthesized and can be custom synthesized. The purity of this compound is high with a purity of 99% or greater for the 3-(2′,4′-dihydroxyphenyl)propionic acid methyl ester.</p>

<p>The chemical name for (3R)-3,6-Dihydro-2H-1,4-thiazine-3,5-dicarboxylic acid 3-ethyl ester-d5 is 2-(2-(pyrrolidin-1-yl)ethoxy)ethanol. This compound is a drug product that has been custom synthesized and purified by HPLC. It is an analytical standard and impurity standard for HPLC. The CAS number for this compound is 944115-20-2.</p>

<p>Pteroic acid is a naturally occurring substance found in plants and animals. It has inhibitory activities against enzymes such as butyrate kinase, acetyl-CoA synthetase, and glutamate dehydrogenase. Pteroic acid is used to synthesize quinoxalines, which are used for the treatment of cancer. Pteroic acid also inhibits cell growth by inhibiting protein synthesis. This is done by conjugating with amino acids and inhibiting their uptake into the ribosome. The inhibition of glutamate dehydrogenase may be due to its ability to reduce levels of glutathione, which is an inhibitor of this enzyme.</p>

<p>Tenofovir dimer triethylammonium salt is a potent inhibitor of protein kinase that has been shown to induce apoptosis in cancer cells. This Chinese medicinal analog has been found to be effective against various types of cancer, including bladder, prostate, and breast cancer. Tenofovir dimer triethylammonium salt works by inhibiting the activity of enzymes involved in cell cycle regulation and inducing cell death through apoptotic pathways. This drug is also an effective inhibitor of HIV-1 replication and is used as an antiviral agent. In addition to being an anticancer and antiviral drug, Tenofovir dimer triethylammonium salt has also been reported to have potential therapeutic applications for other diseases such as hepatitis B virus infection and osteoporosis.</p>

<p>1,3-Dihydro-6-methylfuro[3,4-c]pyridin-7-ol is a compound that contains impurities such as fatty acids and uridine. It has been found to be an inhibitor of α-mangostin adduct formation with fatty acids. Additionally, it has been shown to inhibit the activity of GSK-3β, an enzyme involved in various cellular processes. This compound also exhibits inhibitory effects on monascus and safranal, two enzymes involved in the production of certain compounds. Furthermore, it has been found to inhibit calpain, an enzyme responsible for protein degradation. The compound can be used in various research applications involving electrode modification and polylysine immobilization. It may also have potential interactions with other drugs such as cefdinir.</p>

<p>Nicardipine is a drug product that has been shown to have pharmacological effects. It is an anti-anginal agent and vasodilator. Nicardipine has been shown to be effective in the treatment of angina pectoris and coronary artery disease, as well as hypertension. Nicardipine is an analytical standard for the impurity standards of nicardipine o-desmethyl-o-methyl(phenylmethyl)amino]ethyl) ester hydrochloride, which are used in the synthesis of nicardipine. Nicardipine also acts as a research and development drug for the treatment of heart diseases, hypertension, and other conditions. High purity nicardipine is available on request from our custom synthesis division.</p>

<p>1'-Epi-Gemcitabine 3',5'-dibenzoate is an analytical standard that is used in the drug development process. It is also a high purity, API impurity, HPLC standard, and drug product. 1'-Epi-Gemcitabine 3',5'-dibenzoate is an impurity of Gemcitabine, which is an anticancer drug. The impurity can be found in the methanolic fraction of the extract and it's an epimer of Gemcitabine. The pharmacopoeia for this compound are USP and EP. Custom synthesis and natural or synthetic are possible for this compound.</p>

<p>1-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-5-hydroxy-1-pentanone is a drug product that is used as an HPLC standard. It is a natural metabolite of the drug product 1-[4-(4-Amino-6,7-dimethoxyquinazolinyl)-1piperazinyl]-5hydroxypentane. The synthesis of this compound has been reported in the literature.<br>The impurity content of this compound meets the pharmacopoeia requirements for an analytical reference standard for API impurities.</p>

<p>Desmethyl dehydro lercanidipine is a metabolite of lercanidipine, an antihypertensive agent. Lercanidipine is a dihydropyridine calcium channel blocker that inhibits the influx of calcium ions into cardiac muscle cells and vascular smooth muscle cells. The desmethyl form of lercanidipine has been shown to have anti-inflammatory effects in rats with experimental arthritis. It has also been shown to inhibit the production of inflammatory cytokines in lipopolysaccharide-stimulated human peripheral blood mononuclear cells.</p>

<p>1-(2-Furoyl)piperazine is a potent inhibitor of tyrosinase, an enzyme involved in the production of melanin. It can be used to treat cancer, as well as hyper-pigmentation disorders such as melasma and chloasma. 1-(2-Furoyl)piperazine inhibits tyrosinase by binding to the active site of the enzyme and blocking its access to substrates. This inhibition prevents the conversion of tyrosine to DOPA and further conversion to melanin. 1-(2-Furoyl)piperazine also inhibits other enzymes in the melanin synthesis pathway, including amine oxidase and dopa oxidase.</p>

<p>2,2'-Methylenebis[4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol] is a synthetic drug product that is used as a reference standard for HPLC and GC analyses. It is also a metabolite of the drug product 2,2'-methylenebis[4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol], which is used in pharmaceuticals. This impurity standard exhibits analytical properties similar to those of the API impurity.<br>The chemical structure of this compound consists of an aromatic ring with two methyl groups and two methoxy groups attached to it.</p>

<p>Etoricoxib impurity 5 is an impurity of etoricoxib. Etoricoxib is a nonsteroidal anti-inflammatory drug (NSAID) that belongs to the class of selective COX-2 inhibitors. It inhibits the production of prostaglandins and has been shown to reduce inflammation, swelling, and pain in animal studies. Etoricoxib impurity 5 is an impurity standard for HPLC analysis. This compound has not been evaluated by the FDA or other regulatory agencies.</p>

<p>7-Methoxy-N-[2-(7-methoxy-1-naphthalenyl)ethyl]-1-naphthaleneethanamine is a drug product that is a synthetic compound. It has the following analytical data:</p>

<p>Please enquire for more information about rac-7-Oxo-pramipexole hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Deschloro aripiprazole is a drug that belongs to the class of antipsychotics. It is an atypical antipsychotic with a high affinity for human albumin and α1-acid glycoprotein, which are plasma proteins. 2-Deschloro aripiprazole has been shown to interact with human albumin and α1-acid glycoprotein in vitro, and it has been suggested that this interaction may be responsible for its pharmacological effects. 2-Deschloro aripiprazole has also been shown to bind to the dopamine D2 receptor, which is thought to be responsible for its therapeutic effects as an antipsychotic. The molecular interactions between 2-deschloro aripiprazole and human albumin have been studied using isothermal titration calorimetry (ITC) and molecular docking studies. These studies have helped us understand how 2-deschloro aripiprazole binds to human album</p>

<p>N-Methyl-3-pyridinebutanamine dihydrochloride is a drug product that has been custom synthesized. This product is intended for analytical, research and development, or pharmacopoeia purposes. The CAS number of this substance is 3000-74-6. This product includes impurities at levels below 1% (w/w). The purity level of this product is &gt;98% (w/w).</p>

<p>Please enquire for more information about Propamidine monoamide isethionate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about N-(4-Hydroxyphenyl)acetamide sulfate-d3 sodium including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Dasatinib is a cancer drug that is used to treat patients with chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia. It inhibits the activity of tyrosine kinases, in particular Bcr-Abl and Src. Dasatinib is a structural analog of imatinib, which has been shown to be effective against chronic myeloid leukemia by inhibiting the activity of Bcr-Abl. Dasatinib impurity is an unwanted substance found in dasatinib. It can be synthesized from formic acid, chloride and chlorine using a series of industrial processes. The salt form of dasatinib impurity is acidic and synthetic.</p>

<p>Carpropamide is a medicinal compound that acts as an analog of kinase inhibitors. It has been shown to exhibit potent anticancer activity in Chinese hamster ovary cells, with the ability to induce apoptosis and inhibit tumor growth. Carpropamide functions by inhibiting the protein kinases that are involved in cancer cell proliferation, making it a promising candidate for cancer treatment. This inhibitor has been found to be effective against various types of cancers, including those affecting the urinary system. Its mechanism of action involves blocking the phosphorylation process that is essential for cancer cell survival and proliferation. Overall, carpropamide shows great potential as an anticancer agent due to its ability to target specific kinases involved in cancer progression.</p>

<p>Dapsone N-β-D-glucuronide sodium salt is a drug product that is Custom synthesized for your research and development needs. It is available for sale as a white to off-white crystalline powder with a purity of 98%. Dapsone N-β-D-glucuronide sodium salt has CAS No. 54749-81-4, analytical, Metabolism studies, Drug development, Natural, Metabolite, pharmacopoeia, niche, Synthetic, Impurity standard and Research and Development. It is an HPLC standard in the form of a white to off-white crystalline powder with a purity of 98%.</p>