APIs pour la recherche et les impuretés

<p>Rotigotine is a drug that belongs to the group of pharmaceutical formulations. It is an unlabeled drug that has been shown to be effective in the treatment of depression. Rotigotine may be administered through a transdermal patch or by iontophoresis, which is a technique used to administer drugs through the skin. The mechanism of action is not known, but it may involve the inhibition of monoamine reuptake and/or alteration of intracellular levels of catecholamines. Rotigotine sulfate has a high affinity for dopamine receptors and increases plasma concentrations of dopamine by inhibiting its reuptake into presynaptic neurons. This leads to increased concentrations of dopamine in synaptic clefts and an increase in postsynaptic receptor binding.</p>

<p>Alpha-[4-(2-dimethylaminoethoxy)phenyl]stilbene (DS) is a synthetic, analytical standard that is used as an impurity in the manufacture of pharmaceutical products. DS is also sold as a reference material for HPLC and GC/MS analysis.</p>

<p>AG-024322 is an analog of a Chinese medicinal herb that has been found to have potent anticancer properties. It works by inhibiting cyclin-dependent kinases, which are enzymes that regulate the cell cycle and play a crucial role in cancer cell growth. AG-024322 has been shown to induce apoptosis, or programmed cell death, in cancer cells. This inhibitor of protein kinase has also demonstrated efficacy against various types of tumors in human studies. AG-024322 is one of several promising inhibitors of this class currently being developed as potential cancer treatments.</p>

<p>Digitoxigenin mono-β-D-digitoxoside is a potent inhibitor of tumor growth and cancer cell proliferation. It is an analog of the cardiac glycoside digitoxin, which is known for its anticancer properties. Digitoxigenin mono-β-D-digitoxoside has been shown to induce apoptosis in human cancer cells by inhibiting protein kinases such as AKT and ERK1/2. This drug also has potential therapeutic applications in the treatment of ghrelin-related diseases, as it has been shown to inhibit the activity of ghrelin, a hormone that stimulates appetite and promotes weight gain. Additionally, digitoxigenin mono-β-D-digitoxoside exhibits high water solubility due to its cellulose-based structure, making it ideal for use in urine-based diagnostic tests for cancer detection.</p>

<p>Please enquire for more information about Deaminoethyl fluvoxamine β-D-glucuronide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2,4-Dihydroxy-6-propylbenzaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Losartan is a drug product that belongs to the class of losartan impurity. It is an impurity standard for research and development, as well as a custom synthesis. Losartan is also used in the synthesis of other drugs, such as losartan potassium, which is classified as a niche compound. Losartan impurity has been shown to be metabolized by several enzymes including CYP2C9 and CYP3A4. The metabolite identified from this study was N-desmethyl losartan.</p>

<p>Please enquire for more information about L-Trans-1-methyl-4-propyl-2-pyrrolidinecarboxamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>AAK1-IN-1 is a potent inhibitor of the AAK1 kinase, which plays a crucial role in regulating cell cycle progression and apoptosis. This inhibitor has shown promising results in pre-clinical studies for the treatment of cancer, particularly leukemia. AAK1-IN-1 has been found to effectively inhibit the growth of human cancer cell lines and Chinese medicinal tumor cells by blocking the activity of AAK1 kinase. This protein is involved in several cellular processes, including signal transduction pathways and protein trafficking, making it an attractive target for cancer therapy. The use of AAK1-IN-1 as a novel kinase inhibitor may offer new opportunities for developing effective treatments against various types of cancer.</p>

<p>Please enquire for more information about 3,5-Diiodo-4-hydroxy-DL-phenyllactic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-Acetyloxy-N-despropyl ropivacaine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>o-Desisopropyl-o-ethyl cefpodoxime proxetil is a drug product that is used in the treatment of infections caused by bacteria. It is a synthetic, high purity, and natural metabolite that has been developed for the treatment of bacterial infections. This drug product has been shown to have an analytical purity of &gt;99.5% and a pharmacopoeia purity of &gt;99%. o-Desisopropyl-o-ethyl cefpodoxime proxetil is also a metabolite that was synthesized to be used as an impurity standard for HPLC analysis.</p>

<p>Cefdinir impurity H is a metabolite of the drug cefdinir. It is an impurity in the drug product that was discovered during research and development of cefdinir. Cefdinir impurity H has a CAS number, which indicates that it is a drug product. It also has high purity and can be used for analytical purposes or as a metabolism study standard. Metabolism studies have been conducted on this compound to determine its pharmacological effects. This metabolite is not natural, but synthetic and may be considered a niche compound due to its limited use in research and development.br&gt;<br>This impurity may be found in the form of an HPLC standard and can be used for developing new drugs against bacterial infections such as tuberculosis, which are caused by Mycobacterium tuberculosis.br&gt;br&gt;</p>

<p>Please enquire for more information about (5Z,9Z,13E)-Geranylgeranylacetone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Linagliptin Impurity 18 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Pregabalin is an anticonvulsant drug that is used to treat epilepsy, neuropathic pain, and generalized anxiety disorder. It binds to the alpha2-delta subunit of voltage-gated calcium channels and regulates neurotransmitter release. Racemic pregabalin N-acrylamide (Rac-Preg) is a racemic mixture of two enantiomers, S(-)Pregabalin and R(+)Pregabalin. It has been shown to be an analytical standard in HPLC analysis by virtue of its purity and stability. Rac-Preg has been demonstrated as a metabolite of racemic pregabalin in humans and rats. Rac-pregabalin N-acrylamide can be synthesized from the corresponding amine using acylation with acrylic acid chloride followed by hydrolysis with sodium methoxide in methanol.</p>

<p>(S)-3-((S)-5-Oxopyrrolidine-2-carbonyl)thiazolidine-4-carboxylic acid is a synthetic compound that is used as an impurity standard for HPLC. It is also used in drug development and research and development of pharmaceuticals. This product was made through custom synthesis and is not natural.</p>

<p>Pralnacasan is an inhibitor that has been shown to induce apoptosis in cancer cells. It is an analog of a urinary inhibitor and has been found to inhibit the activity of various kinases, including human cancer cell kinases. Pralnacasan has potential as an anticancer drug due to its ability to inhibit tumor growth by interfering with the activity of certain proteins involved in cancer cell proliferation. This medicinal compound has shown promise in Chinese hamster ovary cells and may have applications for treating various types of cancer.</p>

<p>This is a white crystalline compound that has been shown to be effective against glutamic acid-sensitive L-amino acid decarboxylase. It is used as an intermediate in the synthesis of other pharmaceuticals.</p>

<p>5-Desthiopropyl-5-hydroxy-ticagrelor is a synthetic and new chemical entity, which is a prodrug. It is the active metabolite of ticagrelor, an antiplatelet drug used to prevent blood clots. Ticagrelor inhibits platelet aggregation by inhibiting the activity of P2Y12 receptor on the platelet surface. 5-Desthiopropyl-5-hydroxy-ticagrelor has an analytical purity of &gt;97% and a pharmacopoeia grade purity of &gt;99%. The drug product is custom synthesis and high purity, with a molecular weight of 247.9 Da. The impurity standard for this drug product is 5% (w/w) for 5-(3-(2-(3-(3-(dimethylamino)propoxy)propoxy)-pyrrolidinium bromide), also known as 3DAP; 0.1% (w</p>

<p>Cefpodoxime proxetil impurity D is a cephalosporin antibiotic that is an oral prodrug. It is used to treat infections of the mouth, throat, skin, and respiratory tract caused by gram-positive bacteria such as Streptococcus pyogenes (group A), Streptococcus pneumoniae (group B), or Staphylococcus aureus. Cefpodoxime proxetil impurity D can be converted into the active form cefpodoxime in the body. The oral absorption of this drug has been found to be rapid and complete in humans with streptococcal pharyngitis. This drug has been shown to have antibacterial efficacy against penicillin-resistant strains of group A streptococci and Staphylococcus aureus.</p>

<p>1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]thio]-1H-benzi midazole is a high purity analytical standard that is used to calibrate HPLC. It is found as an impurity in the drug product and as a metabolite. 1-[(3-Methyl-4-(2,2,2 -trifluoroethoxy) - 2 - pyridinyl) methyl] - 2 - [[[3 - methyl (4 ( 2 , 2 , 2 - trifluoroethoxy) - 2 pyridinyl) methyl] thio] - 1 H benzimidazole is the IUPAC name for this compound. This chemical has been synthesized</p>

<p>(3S,5R)-Atorvastatin calcium is an analytical standard for the drug atorvastatin. It has a purity of 99.9% and is manufactured in accordance with the requirements of the pharmacopoeia. The product is available as a white crystalline powder and is soluble in water, acetone, and ethanol. (3S,5R)-Atorvastatin calcium has been used in drug development and as an impurity standard for HPLC analysis. It also serves as a metabolite to characterize the production process of atorvastatin.</p>

<p>Atorvastatin N-(3,5-dihydroxy-7-heptanoic acid)amide calcium salt is a synthetic drug product that belongs to the class of statins. It has been used in research and development as a standard for HPLC analysis. The metabolite atorvastatin 3,5-dihydroxy-7-heptanoic acid (CAS No. 1105067-87-5) is also available from Sigma Aldrich. The impurity standards atorvastatin calcium salt and amorphous calcium sulfate are also available from Sigma Aldrich. Atorvastatin N-(3,5-dihydroxy-7-heptanoic acid)amide calcium salt is an API impurity in the synthesis of atorvastatin sodium (CAS No. 120781-93-1).</p>

<p>7-o-Benzyl luteolin is a synthetic compound that is used as an impurity standard for the pharmaceutical industry. It is also a metabolite of luteolin, which can be found in plants such as parsley and sage. The structure of 7-o-benzyl luteolin has been determined using X-ray crystallography. This compound is used in drug development to study metabolism and to develop new drugs with fewer side effects. 7-o-Benzyl luteolin has been shown to have antiinflammatory properties, which may be due to its inhibition of prostaglandin synthesis.END&gt;</p>

<p>Dehydro benidipine is a drug product that has been manufactured to the HPLC standard and is CAS No. 118935-44-7. It is not natural, but it does have a Drug development and Research and Development history. This drug product is an Impurity standard for analytical purposes, and it is also an API impurity. Synthetic studies are required for Metabolism studies, which helps the niche market. High purity of dehyro benidipine ensures that this drug product meets the pharmacopoeia requirements and standards.</p>

<p>Vigabatrin EP Impurity B is a research and development impurity standard that belongs to the class of drugs. It is an impurity in Vigabatrin, a drug product that has been developed for the treatment of epilepsy. Vigabatrin EP Impurity B is a metabolite of vigabatrin and can be found in the urine of patients who have taken this drug. This compound was not detected in other body fluids such as serum or plasma. The chemical name for this impurity is 2,3-dihydro-3-methyl-4-[(2S)-2-[[(1R)-1-[(2S,3R)-2-(dimethylamino)cyclohexyl]ethenyl]amino]-1-piperidinyl]butanoic acid methyl ester hydrochloride.</p>

<p>Please enquire for more information about N-Acetyl-S-[4-(2-pyridinyl)benzyl]-L-cysteine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ssr 180711 hydrochloride is a synthetic compound with a molecular weight of 557.5. It has been used as an analytical reference standard in the development of drugs and as a natural product in research and development. Ssr 180711 hydrochloride is metabolized to form its active form, Ssr 180711, which is an antibiotic that kills bacteria by inhibiting protein synthesis and DNA replication. This drug also inhibits the growth of Mycobacterium tuberculosis, Mycobacterium avium complex, and Staphylococcus aureus. The purity of this product is 99.0% pure (HPLC).</p>

<p>Please enquire for more information about Rel-M-nitro-threo-chloramphenicol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(R,R)-Solifenacin succinate is a pharmaceutical agent that acts as an antimuscarinic drug. It has been shown to be effective in wastewater treatment, where it was found to reduce the amount of solifenacin and optimised organic chemicals in the water. This drug has also been shown to have antagonist properties against the muscarinic receptor M3.</p>

<p>(R)-Diphenyl (((1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate is a high purity, analytical, API impurity, HPLC standard, drug development, niche and drug product. It is an impurity standard for the pharmacopoeia. It is also synthesized from natural or synthetic sources.</p>

<p>Please enquire for more information about Ethyl 2-cyano-4-methylpent-2-enoate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Methyl 4-[[1-(ethoxycarbonyl)-2-oxocyclopentyl]methyl]-α-methylbenzeneacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>6-Bromo-1-hydroxypyrene is a natural metabolite of the aromatic hydrocarbon benzo[a]pyrene. It has been used as an analytical standard for HPLC and GC analyses, and as a research and development (R&amp;D) drug product in pharmacopoeia. 6-Bromo-1-hydroxypyrene has been shown to have anti-inflammatory activities in mouse skin. It also inhibits liver microsomal cytochrome P450 enzymes, suggesting that it may be useful in the treatment of disorders such as Alzheimer's disease.</p>

<p>Hyoscyamine related compound A is a pure, synthetic chemical compound that is used as an impurity standard and can be custom synthesized to meet the requirements of a customer's research and development. Hyoscyamine related compound A is also known as a metabolite in the body, which means it is created from another substance. It is created from the breakdown of Hyoscyamine, which is found in plants such as jimson weed, mandrake, and henbane. Hyoscyamine related compound A has a CAS number of 537-29-1. It can be used to create drug product or pharmacopoeia standards. It has been classified as a custom synthesis by the FDA because it has not been approved for use in humans or animals.</p>

<p>Buprenorphine is a semi-synthetic opioid that is used to treat pain. It has been shown to have high purity, when compared to other synthetic opioids, and is often used as an analytical standard. Buprenorphine furanyl impurity is an impurity in buprenorphine that can be detected by high-performance liquid chromatography (HPLC). It is also a metabolite of the drug and can be used as a pharmacopoeia reference material.</p>

<p>Cefixime is a broad-spectrum oral antibiotic used to treat bacterial infections, including respiratory tract and ear infections. Cefixime is the prodrug of cefixime acid, which is hydrolyzed in vivo to cefixime. This impurity is an analytical standard that can be used for research and development, high purity drug product, API impurity, HPLC standard and niche drugs. It can also be used as a metabolite and an impurity standard. The CAS number for this compound is 1335475-08-5. This chemical has natural or synthetic origins but is not specified.</p>

<p>(1R,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid methyl ester is a drug product that has not yet been approved for use in humans. It is a synthetic compound and its structure is similar to the 1H indole derivative. It is metabolized in both rats and humans by oxidation of the methyl ester side chain. Metabolites have been identified in urine and feces following administration of radiolabeled (1R,3S)-1-(1,3-benzodioxol-5-yl)-2-(2 chloroacetyl)-2,3,4,9 tetrahydro 1H pyrido[3,4 b]indole 3 carboxylic</p>

<p>Pteroic acid is a naturally occurring substance found in plants and animals. It has inhibitory activities against enzymes such as butyrate kinase, acetyl-CoA synthetase, and glutamate dehydrogenase. Pteroic acid is used to synthesize quinoxalines, which are used for the treatment of cancer. Pteroic acid also inhibits cell growth by inhibiting protein synthesis. This is done by conjugating with amino acids and inhibiting their uptake into the ribosome. The inhibition of glutamate dehydrogenase may be due to its ability to reduce levels of glutathione, which is an inhibitor of this enzyme.</p>

<p>6-O-Desmethyl moxonidine is a drug product that is a metabolite of the parent compound, moxonidine. It has been shown to be an impurity in the API (active pharmaceutical ingredient) and is used as an analytical standard for HPLC. 6-O-Desmethyl moxonidine is synthetically prepared and can be found in natural sources, such as plants or animals. The metabolism studies indicate that the substance is excreted unchanged in urine following oral administration and undergoes extensive hydrolysis in liver microsomes to yield 4-hydroxy-3-(3-hydroxymethylpiperidinopropyl) piperidine, which is then oxidized to 3-(4-hydroxypiperidinopropyl)-1H-1,2,4-triazole. This product may cause skin irritation.</p>

<p>Fluticasone furoate EP impurity E is an analytical reference standard for pharmacopoeia and research. It is a synthetic fluticasone furoate EP impurity that has been custom synthesized for use as a high-purity, HPLC-grade standard. Fluticasone furoate EP impurity E is characterized by its natural origin and purity, making it appropriate for use in drug development and research. The CAS number for this product is 398454-97-2.</p>

<p>Labetalol EP impurity D is a metabolite of labetalol that is used as an impurity standard for HPLC. This impurity has been identified in the drug product and also in the drug development process. Labetalol EP impurity D is one of many metabolites that can be formed by cytochrome P450 enzymes. Labetalol EP impurity D is a natural metabolite of labetalol, which can be found in the urine of humans and other mammals. It is also present in various plants and fungi, including mushrooms, lichens, yeast, and barley. Synthetic labetalol EP impurity D can also be produced by various chemical reactions.</p>

<p>Rac-Benzyl phenylephrone hydrochloride is a synthetic compound that is not found in nature. It can be used as an analytical standard or a pharmacopoeia impurity standard. Rac-Benzyl phenylephrone hydrochloride has been shown to inhibit the activity of CYP3A4, an enzyme which metabolizes many drugs. As a result, it may be useful for drug development and research and could have applications in niche markets such as natural products.</p>

<p>Epi-canagliflozin is a drug product that is manufactured by HPLC. It is a natural, synthetic drug development and research and development of the API impurity standard for analytical. The metabolite of this synthetic API impurity standard is used as an analytical impurity in the pharmacopoeia. This synthetic API impurity standard can be custom synthesized to meet your needs.</p>

<p>Salbutamol EP Impurity C is an impurity of Salbutamol EP, which is an active pharmaceutical ingredient. It is a hydrophilic interaction chromatography and reverse-phase high-performance liquid chromatography method that can be used to screen for the presence of impurities in this product. The detection method is based on the use of a diode array detector with a synchronous detection mode. The column used in this screening process is a liquid chromatography column with a particle size of 5 microns and a length of 250 mm, which has been packed with 5% phenyl-95% dimethyl polysiloxane stationary phase. This process requires acetonitrile as the mobile phase, and the detection wavelength ranges from 220 nm to 240 nm.</p>

<p>N-Methyl-3-pyridinebutanamine dihydrochloride is a drug product that has been custom synthesized. This product is intended for analytical, research and development, or pharmacopoeia purposes. The CAS number of this substance is 3000-74-6. This product includes impurities at levels below 1% (w/w). The purity level of this product is &gt;98% (w/w).</p>

<p>Please enquire for more information about Propamidine monoamide isethionate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Dasatinib is a cancer drug that is used to treat patients with chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia. It inhibits the activity of tyrosine kinases, in particular Bcr-Abl and Src. Dasatinib is a structural analog of imatinib, which has been shown to be effective against chronic myeloid leukemia by inhibiting the activity of Bcr-Abl. Dasatinib impurity is an unwanted substance found in dasatinib. It can be synthesized from formic acid, chloride and chlorine using a series of industrial processes. The salt form of dasatinib impurity is acidic and synthetic.</p>

<p>N,N'-Carbonylbis[L-glutamic acid] is a metal chelate that has been used as a fluorescent marker for diagnostic purposes. It has been shown to bind to prostate-specific antigen (PSA) and radiolabelled with positron emitters. This ligand has also been used in the design of novel diagnostic and therapeutic agents for cancer treatment.</p>

<p>N-[4-[2-[[(2R)-2-Hydroxy-2-phenylethyl]amino]ethyl]phenyl]-acetamide is a synthetic drug product that belongs to the class of drugs called acetamides. It is an impurity in the API, Acetaminophen, which is used to treat pain and reduce fever. N-[4-[2-[[(2R)-2-Hydroxy-2-phenylethyl]amino]ethyl]phenyl]-acetamide is also used as a research and development chemical for drug discovery. The compound is made by reacting 4-(aminophenyl)benzeneacetic acid with 2-(hydroxyphenyl)ethanol in the presence of sodium methoxide or lithium chloride. The resulting product has been shown to have antiinflammatory properties and may be useful for treating heart diseases or diabetes.</p>

<p>5-Dimethylaminobutyryl citalopram is a metabolite of the antidepressant drug, Citalopram. It is used as an analytical impurity standard for Citalopram in HPLC and LCMS analysis. 5-Dimethylaminobutyryl citalopram is also a natural product of metabolism and may be found in humans. 5-Dimethylaminobutyryl citalopram has been shown to have similar pharmacological properties to Citalopram in animal studies, which include antihistamine effects and analgesic effects. This compound may be useful as a niche treatment for some patients who are resistant to other drugs.</p>

<p>2-Deoxy-5-O-toluoyl-D-ribofuranose is an analytical standard for the determination of purity in drug products. It is also used as a reference compound for HPLC and as a metabolite to study metabolism. This impurity can be synthesized from D-ribose and 2(3,4,5)-O-benzylidenebutyraldehyde.</p>

<p>Please enquire for more information about PBT Impurity 2 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ethyl 2-methoxy-5-sulfamoylbenzoate is a research and development impurity standard. It is a white to off-white crystalline solid that is soluble in water. The product has been synthesized for use as a drug product, synthetic, and in the synthesis of other compounds. It has also been used as a metabolite in metabolism studies and an analytical standard for HPLC.</p>

<p>Dihydrexidine hydrochloride is a phosphate ion transport inhibitor that binds to the acetylcholine transporter, and inhibits the uptake of acetylcholine in the brain. It is used as an opioid analgesic, as well as to treat depression, cognitive disorders, and Parkinson's disease. Dihydrexidine hydrochloride binds to the catechol-O-methyltransferase (COMT) enzyme and prevents it from breaking down dopamine. This leads to increased levels of dopamine in the synapse and enhanced transmission of nerve impulses between neurons. Dihydrexidine hydrochloride also has been shown to bind to antigen molecules on cells, which may be important for its antiviral properties.</p>

<p>Diclofenac isopropyl ester is a synthetic, non-natural drug product. It has been shown to be metabolized by the liver to produce diclofenac acid and sulfate conjugates. The drug product can be used as an analytical standard or impurity control in HPLC measurements of drug products that contain diclofenac. Diclofenac isopropyl ester is also used for research and development purposes and has niche applications for pharmacopoeia purposes.</p>

<p>2-Oxo ticlopidine oxalic acid is a synthetic compound that has been used as an impurity standard in the synthesis of other compounds. The CAS number for this compound is 89481-79-8. 2-Oxo ticlopidine oxalic acid can be custom synthesized to meet specific requirements. It is typically used as a drug product or pharmacopoeia and can be used for research and development purposes. Metabolism studies have been conducted on 2-oxo ticlopidine oxalic acid, which has shown it to be metabolized through oxidation and conjugation with glutathione, glucuronide, or sulphate. HPLC standards for this compound are available at Sigma Aldrich.</p>

<p>Iso propyl ether abiraterone is a medicinal compound that has shown promising results in the treatment of cancer. It is an inhibitor of CYP17A1, which is a protein involved in the production of androgens such as testosterone. By inhibiting this protein, iso propyl ether abiraterone can reduce the levels of androgens in the body, which can slow or stop the growth of certain types of cancer cells. This compound has been shown to induce apoptosis (cell death) in cancer cells and has demonstrated anticancer activity in both human and Chinese hamster ovary cell lines. Iso propyl ether abiraterone is an analog of other kinase inhibitors and has potential for use in combination with other anticancer drugs.</p>

<p>6,7-Dehydrohyoscyamine (6,7DHHA) is a synthetic alkaloid that is produced by the dehydration of hyoscyamine. It has been shown to be an effective anti-inflammatory agent in both in vitro and in vivo experiments. 6,7DHHA also has a skeleton that is similar to the neurotransmitter acetylcholine, which may account for its effectiveness as an anti-spasmodic drug. This compound has been shown to inhibit the transfer of nerve impulses across synapses by blocking presynaptic acetylcholine receptors. It does this by binding with high affinity to these receptors and preventing them from being activated. 6,7DHHA binds noncompetitively to the receptor site on the acetylcholine receptor and can cross the blood-brain barrier because it is lipid soluble. The biosynthesis of 6,7DHHA starts with two molecules of L-phenylalanine condensed together with one molecule of L-</p>

<p>Aripiprazole impurity is a synthetic impurity that is used as an impurity standard for the pharmaceutical industry. It is used to test the purity of drug products and to assess the quality of raw materials. Aripiprazole impurity is also used in metabolite profiling studies, analytical testing, and pharmacopoeia research and development. This compound has a CAS number of 1797983-65-3.</p>

<p>Brobactam is a potent inhibitor of beta-lactamase enzymes and is often used in combination with other antibiotics to enhance their efficacy. It has been shown to be effective against gram-negative bacteria, including those that are resistant to other antibiotics. Brobactam has also been investigated for its potential use in cancer treatment. Studies have shown that brobactam can induce apoptosis in cancer cells by inhibiting kinase activity, which is essential for cell survival and proliferation. In addition, brobactam analogs have been developed that show promising anticancer activity against human cancer cell lines and Chinese hamster ovary cells. Overall, brobactam has the potential to be a valuable tool in the fight against both bacterial infections and cancer.</p>

<p>3-Descyano febuxostat ethyl ester is a synthetic, natural, and API impurity. 3-Descyano febuxostat ethyl ester is used as an analytical standard in drug development. It is also used as a custom synthesis, impurity standard and analytical reference material.</p>

<p>16alfa-methyl-11beta,21-dihydroxy-6beta,9alfa-difluoropregnane-1,4-diene-3,20-dione-21-valerate is a synthetic drug product with the CAS number of 51622-42-5. The molecular weight is 471.82 g/mol and it has a purity of &gt; 98%. It is an analytical standard for the metabolite of 16alfa methyl 11beta,21 -dihydroxy 6beta,9alfa difluoropregnane 1,4 diene 3,20 dione 21 valerate. This compound also acts as a research and development standard for HPLC and can be used to study metabolism studies.</p>

<p>Loxapine N-oxide is a metabolite of loxapine. It has been shown that the n-oxide form of loxapine has regulatory effects on the metabotropic glutamate receptor and can be used to treat symptoms of schizophrenia. Loxapine N-oxide has been shown to have antipsychotic effects in vitro. The structural formula for loxapine N-oxide is as follows:</p>

<p>Avanafil impurity 26 is a metabolite of avanafil that has been synthesized for use as an impurity standard. It is a white to off-white crystalline powder and has a purity of 99% or greater. Avanafil impurity 26 is insoluble in water and soluble in methanol, ethanol, and acetone.</p>

<p>N-[2-[[[5-[(Dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-nitroacetamide is a metabolite of the drug product, Impurity standard. It is an impurity in the drug product that can be used as a research and development, custom synthesis, or drug product impurity. This impurity has been shown to have potential as an analytical standard and may be useful for pharmacopoeia or API impurities. The compound is also a metabolite of the drug product, which can be used to study metabolism.</p>

<p>Cis-ethyl 2-hydroxyimino-3-oxobutyrate is an organic acid that can be used as a reagent for the detection of primary amines and chiral amines. It is used to detect the presence of formaldehyde, acetamide, and other amine compounds in organic extracts. Cis-ethyl 2-hydroxyimino-3-oxobutyrate reacts with primary amines to form a tertiary amine that can be detected by chromatography or by spectrophotometry. This product is used as a chromatographic reagent for the determination of histidine, hydrochloric acid, and chiral molecules.<br>Cis-ethyl 2-hydroxyimino-3-oxobutyrate is extracted from nitrite and acetate group using solvents such as chloroform or ethyl acetate. The extract can then be separated using chromatography methods such as gas chromatography (GC) or</p>

<p>3-[4-(2-Pyridylsulfamoyl)phenyl] sulfasalazine is an analytical standard and a metabolite of sulfasalazine. It is used as a reference compound in the analysis of high purity sulfasalazine by HPLC. 3-[4-(2-Pyridylsulfamoyl)phenyl] sulfasalazine is also used as an impurity in the drug product, API, and drug development. The CAS number for 3-[4-(2-Pyridylsulfamoyl)phenyl] sulfasalazine is 1391062-34-2.</p>

<p>Cp-66713 mesylate is a synthetic drug product with a molecular formula of C17H19NO2 and a molecular weight of 269.34. It has the following CAS number: 91896-58-1. The purity of this compound is &gt;99% (HPLC).</p>

<p>Impurity A is an impurity of the drug product, dexamethasone. The impurity is a natural metabolite of dexamethasone that is found in the urine of patients taking this medication. Impurity A is chemically identified using HPLC and its purity verified using GC-MS and LC-MS. This impurity can be used as a reference standard for analytical purposes and as an impurity standard for pharmacopoeia testing.</p>

<p>N-Formyl oxcarbazepine is a metabolite of carbamazepine which is a drug product for the treatment of epilepsy. It has been shown to be an effective drug for the treatment of epilepsy and bipolar disorder. This metabolite can be synthesized from carbamazepine, which is a natural product, or by chemical synthesis. N-Formyl oxcarbazepine is used as an analytical standard in HPLC methods and as an impurity standard in API preparations. The pharmacopoeia lists this compound as an impurity in the pharmacopoeia monograph for carbamazepine.</p>

<p>N-Methyltaxol C is an amide derivative of the taxane family. It has been shown to increase systolic pressure in animal models and acts as a cardiac depressant. N-Methyltaxol C also has arrhythmogenic properties, which may be due to its ability to inhibit the inward flow of potassium ions through the cardiac membrane. This drug is being studied for its potential use in cancer treatment, specifically for cancer that arises from breast cells. N-Methyltaxol C has been shown to inhibit the growth of human breast cancer cells in vitro and to induce apoptosis in these cells. The mechanism by which it does this is not yet known, but it is thought that it may work by interfering with cell cycle progression or DNA synthesis by inhibiting protein synthesis or DNA replication.</p>

<p>Haloperidol is a drug belonging to the group of typical antipsychotics. Haloperidol nonanoate is a haloperidol prodrug that is administered in an oily solution and hydrolyzed to release the active form, haloperidol, in vivo. Haloperidol nonanoate has been shown to be an impurity standard for HPLC analyses and as such may be used as a reference compound for quality control purposes. It is also used as an analytical reference material for the determination of natural or synthetic impurities in APIs. Haloperidol nonanoate has been developed by custom synthesis and research and development, with the goal of producing high purity pharmaceuticals.</p>

<p>Indacaterol is a drug product that belongs to the class of drugs known as beta-adrenergic agonists. It is used for the treatment of asthma and COPD. Indacaterol impurity 3 (ID3) is an impurity found in indacaterol, which has been identified as a metabolite of indacaterol. ID3 is not active against bacteria. ID3 has been shown to be synthesized by human liver microsomes and erythrocytes in vitro. ID3 can be purified from indacaterol by HPLC with a purity greater than 99%.</p>

<p>Midostaurin Impurity 1</p>

<p>3-[2-[4-(6-Fluoro-2-benzoxazolyl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one is a synthetic compound that functions as a drug product. It is not found in nature and has been synthesized for use as an API impurity. The CAS number for this compound is 1005191-81-0. 3-[2-[4-(6-Fluoro-2 -benzoxazolyl)-1 -piperidinyl]ethyl]-6,7,8,9 tetrahydro 2 methyl 4H pyrido 1 2 a pyrimidin 4 one has been studied in metabolism studies. It is also known to have niche applications in analytical chemistry and research and development.</p>

<p>8-Methyl etodolac is an impurity of etodolac that is used in the drug development and analytical chemistry industry. It is a synthetic metabolite of etodolac, which is an analgesic agent that belongs to the group of non-steroidal anti-inflammatory drugs (NSAIDs). 8-Methyl etodolac is primarily excreted unchanged in urine and has been used as an HPLC standard for this purpose. It also serves as a pharmacopoeia reference material for the determination of purity and impurities in drug products.</p>

<p>Please enquire for more information about Rivaroxaban impurity 79 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ketoconazole Impurity A is a synthetic impurity of Ketoconazole, which is used as an anti-fungal agent. Ketoconazole Impurity A can be found in ketoconazole formulations and also in ketoconazole synthesized by the body. Ketoconazole Impurity A is a metabolite of Ketoconazole and has been shown to have cytotoxic effects on human cells in vitro. Ketoconazole Impurity A has been shown to inhibit RNA synthesis and protein synthesis, leading to cell death. The cytotoxic effects of this drug are due to its ability to bind DNA and inhibit DNA synthesis. It also inhibits the activity of beta-lactamase, an enzyme that breaks down penicillin antibiotics.</p>

<p>Bupropion impurity 9 is a diphosphate and it has novel, high quality, DNA. CAS No. 2133460-43-0 Nucleosides are modified by phosphoramidites and synthesized from deoxyribonucleosides. Antiviral, anticancer, and antiproliferative ribonucleosides are synthetic. It is of high purity and it is used as a chemical intermediate for the production of nucleic acids and antivirals.</p>

<p>Didesmethylchlorpromazine hydrochloride is an antitumor agent that is resistant to multidrug resistance. It is a potent inhibitor of DNA synthesis and has been shown to sensitize resistant cells to other drugs. Didesmethylchlorpromazine hydrochloride was found to have cytotoxic activity against various human tumor cell lines, including multidrug-resistant cells. However, it did not show any significant activity against normal cells.</p>

<p>Mono(3-hydroxybutyl)phthalate-d4 is a research and development, impurity standard, custom synthesis, drug product, synthetic and high purity chemical that is used as an analytical standard in the pharmacopoeia. Mono(3-hydroxybutyl)phthalate-d4 is also a metabolite of monobutyl phthalate. This product has been shown to be an active substrate for human cytochrome P450 enzymes and has been used to study the metabolism of this compound. Mono(3-hydroxybutyl)phthalate-d4 can be synthesized from commercial chemicals such as pivalic acid, naphthalene or 2-(2'-methylpropoxy)-ethanol with butyric acid in the presence of aluminum chloride. The CAS number for this compound is 57074-43-8 and it should be stored at -20°C.</p>

<p>Capecitabine is a prodrug that is converted to 5-fluorouracil in the body. It has been used for many years in the treatment of breast cancer and colorectal cancer. Capecitabine 2',3'-cyclic carbonate is an analytical standard, research and development tool, high purity drug product, and impurity standard for HPLC analysis. This compound is also used as a pharmacopoeia reference material for quality control testing. Capecitabine 2',3'-cyclic carbonate can be custom synthesized or purified from natural or synthetic sources.</p>

<p>Metabolite of mupirocin</p>

<p>Sofosbuvir impurity 6 is an impurity in the drug Sofosbuvir. It is a metabolite that is a by-product of the synthesis process of Sofosbuvir, which is used to treat chronic hepatitis C infection. The purity of this compound has been tested with HPLC and found to be 99.99% pure. This compound can also be synthesized from natural or synthetic sources.</p>