APIs pour la recherche et les impuretés

Applications Can be used in the preparation of CCR5 antagonists, for treatment of HIV-1.
References Tallant, M. et al., Bioorg. Med. Chem. 21, 1394 (2011)

Applications Quinoline derivative used in the preparation of compounds with anticonvulsant activity as well as compounds with potent antibacterial activity against gram-positive pathogens.
References Guo, L. et al.: Eur. J. Med. Chem., 44, 954 (2009); Jarvest, R.L. et al.: J. Med. Chem., 45, 1959 (2002);

Applications A reactant used in the preparation of Methyl-D-erythritol Phosphate, a substrate in terpenoid biosynthesis.
References Koppisch, A. & Poulter, C.: J. Org. Chem., 67, 5416 (2002)

Applications N-[2-Hydroxy-1,1-bis(hydroxymethyl)ethyl]carbamic Acid Benzyl Ester is an intermediate used in the preparation of glycocluster peptides.
References Shaikh, H. et al.: Carbohydrate Res., 34, 1665 (2008)

Betamethasone EP Impurity G is an analytical impurity that is found in the drug product Betamethasone EP. It is also a natural, synthetic, and custom synthesis impurity that has been manufactured to be an impurity standard. Betamethasone EP Impurity G has a CAS number of 85700-75-0 and is a niche HPLC standard for research and development purposes. This high purity impurity may be synthesized from other chemical compounds or created synthetically.

1-Phenyl-1-(pyridin-4-yl)ethanol is an analytical standard that is used in drug development. It is a metabolite of the anti-inflammatory drug, ketorolac. The purity of 1-phenyl-1-(pyridin-4-yl)ethanol is >98% and it can be custom synthesized to meet specific requirements.

3-(N-Phenyl-N-methyl)aminoacrolein is a hydrophobic compound that has been shown to reversibly bind to serum albumin. This binding leads to a decrease in the lipid content of lipoproteins and a decrease in the rate of their metabolism. These effects are mediated by hydrophobic interactions with the hydrophobic regions of serum albumin. 3-(N-Phenyl-N-methyl)aminoacrolein also interacts with human serum albumin, which is involved in lipid transport and metabolism, and can be used as a contrast agent for X-ray diffraction studies.