APIs pour la recherche et les impuretés

Sodium picosulfate EP Impurity A is a drug product, analytical, Metabolism studies, Natural, API impurity, CAS No. 32500-19-9, Custom synthesis, Impurity standard, Synthetic, Drug development and Research and Development.

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Lactiflorin is a natural compound that has been found to have potent inhibitory effects on cancer cells. This medicinal plant extract is commonly used in Chinese traditional medicine as an anticancer agent. Lactiflorin has been shown to induce cell cycle arrest and promote apoptosis in human cancer cells by inhibiting the activity of protein kinases, which are essential for tumor growth and survival. Additionally, lactiflorin analogs have been developed with even greater potency against cancer cells. In preclinical studies, lactiflorin and its derivatives have demonstrated promising results as potential therapeutic inhibitors for various types of cancers. Furthermore, lactiflorin has also shown potential as a non-invasive biomarker for early detection of certain cancers through analysis of urine samples.

N-Ethoxycarbonyl dabigatran ethyl ester is a synthetic compound that is an impurity in the drug product, Dabigatran etexilate (CAS No. 1416446-40-6) which is used for the treatment and prevention of thromboembolic events. The compound was synthesized by reacting N-ethoxycarbonyl-dabigatran with ethyl acetate in the presence of a base. It has been shown to be stable when stored at 4°C for one year and does not degrade when heated at 37°C for four hours. This impurity has been characterized and its purity confirmed by HPLC analysis.

Amlodipine besilate impurity A is a low-energy impurity that is formed in the crystallization process. It is an amide compound that has a hydrogen bond with crotonic acid and amlodipine, and can be found in acidic environments. The structural formula for this impurity is C8H14NO2S·C4H6O4·CH3OH.

7-(But-2-yn-1-yl)-8-(3-(1,3-Dioxoisoindolin-2-yl)piperidin-1-yl)-3-methyl-1-(4-methylquinazolin-2(4H)-yl)methyl)-1H -purine-2,6(3H,7H)-dione is a synthetic drug that has been modified to have a higher flow rate. It is used in the synthesis of other drugs. The impurities of this drug are determined by the modifications made to its structure and are classified as either natural or synthetic. Linearity is the degree to which a chemical reaction proceeds in one direction without branching or doubling back on itself. This drug utilizes chromatography for quantification purposes and can be found in the form of either an acid or an ester. Formic acid and acetonitrile are two solvents that can be utilized for this drug's elution from

α-(4-Chlorophenyl)-2-ethyl-1,3-dioxolane-2-acetonitrile is a metabolite of the drug product α-[4-(chlorophenyl)phenoxy]ethanol. It has been used as an impurity standard for HPLC and as a pharmacopoeia.
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3-Des(2-methylpropyl)-3-N-butyl tetrabenazine is a synthetic drug product that has been studied in metabolism studies. It is an API impurity with the CAS No. 19328-35-9 and is a custom synthesis. 3DMBT has an analytical standard that can be used to measure its purity and quality. This drug product can be used for research and development, niche, or as a HPLC standard. The purity level of this drug is high and it complies with pharmacopoeia standards.

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Dimethrimol is a medicinal compound that has shown potential as an anticancer agent. It is an analog of inhibitors found in Chinese urine that have been used for their apoptotic effects on cancer cells. Dimethrimol has been shown to inhibit kinases, which are enzymes involved in cell signaling and proliferation. This inhibition leads to apoptosis, or programmed cell death, in human cancer cells. Dimethrimol is a promising inhibitor of tumor kinase activity and may be useful in the development of new anticancer therapies. Its protein kinase inhibitory activity makes it a valuable tool for studying the molecular mechanisms underlying cancer cell growth and survival.