APIs pour la recherche et les impuretés

Salmeterol ep impurity A is an API impurity in the drug product 1-(RS)-1-[4-hydroxy-3-(hydroxymethylphenyl]-2-[(4-phenylbutyl)aminoethanol. It is a synthetic, natural, and pharmacopoeia impurity standard. The CAS number for this compound is 1798014-51-3. Salmeterol ep impurity A has a molecular weight of 255.9 g/mol and chemical formula of C24H30ClNO5.

Tris(trifluoroacetoxy)iodine is an analog of iodine that has shown promise as an anticancer agent. It works by inhibiting kinase activity, which can disrupt the cell cycle and lead to apoptosis in cancer cells. Tris(trifluoroacetoxy)iodine has been found to be effective against a variety of human cancer cell lines, including those resistant to other anticancer agents. In addition, it has been shown to inhibit elastase activity and may have potential as an inhibitor of protein degradation in cancer cells. Overall, Tris(trifluoroacetoxy)iodine holds great potential as a new class of anticancer inhibitors with promising results for tumor treatment.

Desmethyl dabrafenib is a synthetic drug product that is used in research and development. It is an impurity standard for dabrafenib, a prodrug of dabrafenib which has been shown to inhibit the growth of cancer cells by inhibiting the synthesis of proteins. Desmethyl dabrafenib is metabolized through CYP3A4/5-mediated oxidation and glucuronidation. It also undergoes phase I metabolism through CYP1A2 and 2C19, leading to formation of a major metabolite with no activity. This compound has been shown to have natural sources in plants such as rhubarb and soybeans.

FR900359 is a drug product that is custom synthesized and characterized. It has a purity of 99% and CAS No. 107530-18-7. This product is used in metabolism studies, natural drug development, pharmacopoeia, and research and development. The impurity standard for this product is HPLC standard.

N-Nitroso N-hydroxy cyclohexanamine is an analog of betamethasone and a potent inhibitor of kinases. It has been shown to have anticancer properties by inducing apoptosis in cancer cells. This compound is excreted in urine and has been studied extensively in Chinese populations for its potential as an anticancer agent. N-Nitroso N-hydroxy cyclohexanamine inhibits the activity of kinases, which are important enzymes involved in cell signaling pathways that regulate cell growth and division. This inhibition leads to the suppression of tumor growth and the induction of apoptosis in cancer cells. Additionally, this compound has been found to be a potent inhibitor of vitamin D receptor (VDR) and may play a role in regulating VDR-mediated gene expression.

((E)-5-((M-[(2-Carboxyethyl)carbamoyl]phenyl)azo)-2-salicylic acid) is a drug product. It is a synthetic, white to off-white powder that has a molecular weight of 246.9 g/mol and an assay of 99%. The impurity standard for this product is (E)-5-(4-(methylsulfonyl)phenylazo)-2-salicylic acid.

1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-b enzimidazole is an impurity of a drug product. It is a metabolite that has been shown to be present in human plasma and urine. This compound is synthetically produced and is not found in nature. It has been shown to have niche applications in both analytical chemistry and pharmacopoeia.

Vortioxetine Impurity 25 is a drug product that is an analytical impurity. It is a natural impurity found in the synthetic process of Vortioxetine, which is an active pharmaceutical ingredient (API). It has been shown to have pharmacological effects in humans and animals. This compound has been synthesized for use as a standard for HPLC assays. The CAS number for this substance is 1639263-80-1.

Lamivudine is an antiviral drug that belongs to the group of nucleoside analogues. It is a prodrug that is activated by intracellular phosphorylation to form the active compound, lamivudine triphosphate (L-TTP). L-TTP inhibits viral replication by competing with natural substrates for incorporation into viral DNA. The antiviral activity of L-TTP has been shown in animals and humans with hepatitis B virus or human immunodeficiency virus type 1 (HIV-1) infections. Lamivudine S-oxide is a stereoselective form of lamivudine, which can be used for chemoprophylaxis against the pandemic H1N1 virus. This drug has shown to have a lower toxicity profile than other drugs used for this purpose.

Valganciclovir related compound G is a drug product. It has been synthesized in our lab. Valganciclovir related compound G is not an approved drug and is not currently available in the market. Valganciclovir related compound G is a high purity analytical standard that can be used for metabolism studies, natural product research, synthetic research, and pharmacopoeia. Valganciclovir related compound G is a metabolite of valganciclovir and can be used as an impurity standard for HPLC analysis.

Ibuprofen EP impurity H is an impurity of ibuprofen. It is a white crystalline powder with a melting point of 182-184°C and a molecular weight of 253.3. Ibuprofen EP impurity H can be synthesized in high purity by reacting 4-bromobenzenesulfonyl chloride with 2-hydroxybenzoic acid in the presence of triethylamine. This impurity has been used as a standard for drug product analysis, pharmacopoeia standards, drug development, and metabolism studies. Ibuprofen EP impurity H can be identified by HPLC using a retention time of 17.2 minutes and an UV absorption maximum at 254 nm.

Hexetidine impurity A is an impurity in the drug product that is not present in the natural extract. The compound has been synthesized for use as an analytical standard and pharmacopoeia reference material. Hexetidine impurity A can be used to develop a high-purity HPLC standard for hexetidine. The compound has been studied extensively in drug development research and development, and is also used as a synthetic intermediate in niche chemical synthesis.

4-Hydroxymethyl-5-methylimidazol (HMMI) is a corrosion inhibitor that is used in the production of nanomaterials. It has been shown to be an effective treatment for wastewater containing hydrochloric acid and organic solvents. The reaction between HMMI and the acids in wastewater forms a complex that prevents the corrosion of metal surfaces. HMMI can be synthesized by reacting aesculus with formaldehyde in an organic solvent, such as acetone or chloroform, at room temperature. HMMI has also been shown to have antiviral potency and is used in skin care products, such as lotions and shampoos, due to its ability to penetrate the skin barrier. Magnetic resonance spectroscopy (MRS) was used to study the effect of HMMI on skin cells, while electrochemical methods were used to investigate how it inhibits viral activity.

4-Oxo diazepam is an impurity that is found in the production of 4-oxodiazepam, a drug product. It has been used in analytical applications as a natural impurity and as an impurity standard. It has also been used in pharmacopoeia to develop high purity standards for HPLC.

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4-Hydroxy azithromycin is an impurity of Azithromycin that is a metabolite of the drug. 4-Hydroxy azithromycin is a synthetic product, which has been synthesized for use as an analytical standard for HPLC and LC-MS/MS. It has also been used as a pharmacopoeia standard for testing antibiotic purity and quality. Metabolism studies have shown that 4-hydroxy azithromycin is not absorbed from the gastrointestinal tract, but is found in the urine and feces.

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Ribosamine is a medicinal compound that has shown potential as an anticancer agent. It is a kinase inhibitor that targets specific proteins involved in cancer cell growth and survival. Ribosamine has been studied extensively in Chinese medicine and has been shown to induce apoptosis, or programmed cell death, in cancer cells. This compound has also demonstrated the ability to inhibit the growth of tumors by blocking the activity of certain enzymes involved in tumor progression. Ribosamine may also have therapeutic applications beyond cancer treatment, such as its ability to inhibit chitin synthesis and heparinase activity. Its unique properties make it a promising candidate for further research into novel cancer therapies.